CN220530462U - Atomization drug administration simulation device - Google Patents
Atomization drug administration simulation device Download PDFInfo
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- CN220530462U CN220530462U CN202321684232.4U CN202321684232U CN220530462U CN 220530462 U CN220530462 U CN 220530462U CN 202321684232 U CN202321684232 U CN 202321684232U CN 220530462 U CN220530462 U CN 220530462U
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- control module
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- atomizing cup
- air pump
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- 238000004088 simulation Methods 0.000 title claims abstract description 19
- 238000000889 atomisation Methods 0.000 title abstract description 22
- 238000001647 drug administration Methods 0.000 title abstract description 13
- 230000029058 respiratory gaseous exchange Effects 0.000 claims abstract description 60
- 230000000241 respiratory effect Effects 0.000 claims abstract description 39
- 239000003814 drug Substances 0.000 claims abstract description 36
- 238000000034 method Methods 0.000 claims abstract description 22
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 238000001179 sorption measurement Methods 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000012377 drug delivery Methods 0.000 claims description 19
- 238000000105 evaporative light scattering detection Methods 0.000 claims description 6
- 238000012360 testing method Methods 0.000 abstract description 17
- 229940079593 drug Drugs 0.000 description 8
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 4
- 238000004891 communication Methods 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 238000002663 nebulization Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 241001330002 Bambuseae Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 230000009325 pulmonary function Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
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- Medicinal Preparation (AREA)
Abstract
The embodiment of the application belongs to the technical field of medical equipment, and relates to an atomization drug administration simulation device, which comprises: the device comprises an air pump, an atomizing cup, a breathing filter, a breathing impedance simulator and a breathing tube; the air pump, the atomizing cup, the breathing filter, the breathing impedance simulator and the breathing cylinder are connected through an air path pipe in sequence; the liquid medicine is placed in the atomizing cup, a push-pull rod is arranged on the breathing tube, in the process of controlling the push-pull rod to simulate inhalation, flowing gas generated by the air pump passes through the atomizing cup to generate atomized air flow, and the atomized air flow sequentially passes through the breathing filter and the breathing impedance simulator to enter the breathing tube; the respiratory filter is provided with an adsorption device, and the adsorption device is used for adsorbing atomized liquid medicine and water vapor in gas. The technical scheme that this application provided provides a testing arrangement that can simulate the atomizing process of dosing, can replace the tester to carry out the test of dosing that atomizes.
Description
Technical Field
The application relates to the technical field of medical instruments, and more particularly relates to an atomization drug administration simulation device.
Background
With the rise of respirators and pulmonary function medical equipment, diagnosis and treatment of respiratory diseases by an atomized drug administration device have become a new trend, and in order to improve the diagnosis precision and obtain a better treatment effect, the precision of the atomized drug administration process is further required.
When the atomized medicine is administered, a tester needs to breathe after accessing the suction nozzle of the atomized medicine administration device, and the atomized medicine is inhaled when inhaling. For accurate control of the dosing process, it becomes critical to determine relevant parameters of the aerosolized dosing device during the dosing process, such as the rate of nebulization of the nebulization pump, which require extensive testing of the aerosolized dosing device to accurately determine.
However, when testing the atomized drug delivery device, the tester cannot excessively inhale the drug, and cannot meet the requirements of multiple tests and continuous tests, so it is highly desirable to design a testing device capable of simulating the atomized drug delivery process so as to replace the tester to perform the atomized drug delivery test.
Disclosure of Invention
The technical problem to be solved by the embodiment of the application is how to provide a testing device capable of simulating an atomization drug administration process so as to replace a tester to perform atomization drug administration test.
In order to solve the above technical problems, the embodiment of the present application provides an atomization administration simulation device, which adopts the following technical scheme:
the device comprises an air pump, an atomizing cup, a breathing filter, a breathing impedance simulator and a breathing tube;
the air pump, the atomizing cup, the breathing filter, the breathing impedance simulator and the breathing cylinder are connected through an air path pipe in sequence;
the liquid medicine is placed in the atomizing cup, a push-pull rod is arranged on the breathing tube, in the process of controlling the push-pull rod to simulate inhalation, flowing gas generated by the air pump passes through the atomizing cup to generate atomized air flow, and the atomized air flow sequentially passes through the breathing filter and the breathing impedance simulator to enter the breathing tube;
the respiratory filter is provided with an adsorption device, and the adsorption device is used for adsorbing atomized liquid medicine and water vapor in the atomized airflow.
In some possible implementations, the aerosolized drug delivery device further includes a control module, the control module being electrically connected to the air pump.
In some possible implementations, the atomized medicine feeding device further includes a control module, an electromagnetic valve is further arranged on the air path between the air pump and the atomizing cup, and the control module is electrically connected with the electromagnetic valve.
In some possible implementations, the atomizing cup further includes a mass detection module electrically connected with the control module, the mass detection module configured to detect a mass of the atomizing cup.
In some possible implementations, a control module is disposed on the push-pull rod, and the control module is electrically connected with the control module, and is used for controlling the push-pull rod by using the control module.
In some possible implementations, a flow sensor may be further disposed on the gas path between the atomizing cup and the respiratory filter, and the control module is electrically connected with the flow sensor.
Compared with the prior art, the embodiment of the application has the following main beneficial effects:
the atomizing simulation device of dosing that this application embodiment provided is including air pump, atomizing cup, breathe filter, breathe impedance simulator and breathe the section of thick bamboo, and communicates through the gas circuit pipe between each subassembly. Wherein, the liquid medicine has been placed in the atomizing cup, is provided with the push-and-pull rod on the breathing tube, and in the simulation of controlling the push-and-pull rod and inhaling the in-process, the flow gas that the air pump produced produces the atomizing air current behind the atomizing cup, and the atomizing air current gets into in the breathing tube after breathing filter and breathing impedance simulator in proper order. The breathing filter is provided with the adsorption device, and the adsorption device can adsorb atomized liquid medicine and water vapor in gas, so that the atomized liquid medicine is prevented from entering the breathing cylinder. Therefore, the atomization drug administration simulation device can simulate the breathing process of a human body, and replaces a tester to perform atomization drug administration test.
Drawings
For a clearer description of the solution of the present application, a brief introduction will be given to the drawings needed in the description of the embodiments, which are some embodiments of the present application, and from which other drawings can be obtained for a person skilled in the art without the inventive effort.
FIG. 1 is a schematic view of an embodiment of an aerosolized drug delivery simulation device according to an embodiment of the present application;
fig. 2 is a schematic view of another embodiment of an aerosolized drug delivery simulation device according to an embodiment of the present application.
Reference numerals: 110. an air pump; 120. an atomizing cup; 130. a respiratory filter; 140. a respiratory impedance simulator; 150. a respiratory tube; 160. a control module; 170. electromagnetic valve
Description of the embodiments
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used in the description of the applications herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application; the terms "comprising" and "having" and any variations thereof in the description and claims of the present application and in the description of the figures above are intended to cover non-exclusive inclusions. The terms first, second and the like in the description and in the claims or in the above-described figures, are used for distinguishing between different objects and not necessarily for describing a sequential or chronological order.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the present application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.
In order to better understand the technical solutions of the present application, the following description will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the accompanying drawings.
As shown in fig. 1, fig. 1 is a schematic diagram of an embodiment of an aerosolized drug administration simulation device according to an embodiment of the present application, including:
an air pump 110, an atomizing cup 120, a respiratory filter 130, a respiratory impedance simulator 140, and a respiratory cartridge 150;
the air pump 110, the atomizing cup 120, the breathing filter 130, the breathing impedance simulator 140 and the breathing tube 150 are connected in sequence through an air pipe;
the liquid medicine is placed in the atomizing cup 120, a push-pull rod is arranged on the breathing tube 150, in the process of controlling the push-pull rod to simulate inhalation, the flowing gas generated by the air pump 110 passes through the atomizing cup 120 to generate atomized air flow, and the atomized air flow sequentially passes through the breathing filter 130 and the breathing impedance simulator 140 and then enters the breathing tube 150;
the respiratory filter 130 is provided with an adsorption device, and the adsorption device is used for adsorbing atomized liquid medicine and water vapor in the atomized airflow.
In this embodiment, the air pump 110, the atomizing cup 120, the respiratory filter 130, the respiratory impedance simulator 140 and the respiratory tube 150 are connected through the air passage pipe in sequence, so as to realize the air passage conduction between each component.
The air pump 110 may also be referred to as an air compressor or a compressor, and the atomizer may also be referred to as an atomizing cup 120 or an atomizing device. The air pump 110 is used for pumping air to generate flowing air, and the atomizer is used for containing liquid medicine and atomizing administration. In the atomization operation process, the air pump 110 is controlled to output flowing air to the atomizer, and the flowing air causes the liquid medicine in the atomizer to be atomized at the moment due to the pressure difference between the input port and the output port of the atomizer, so that the medicine is atomized and output to the respiratory filter 130 from the mist outlet of the atomizing cup 120, and the atomization administration effect is achieved.
The breathing filter 130 is provided with an adsorption device, such as a gauze structure, one end of the breathing filter 130 is connected to the mist outlet of the atomizing cup 120, the other end is connected to the breathing impedance simulator 140, and the adsorption device can be used for adsorbing the medicament and the water vapor in the atomized airflow, so that the medicament and the water vapor are prevented from entering the breathing tube 150, the equipment is polluted, and the breathing filter 130 can be replaced as required.
The respiratory impedance simulator 140 is connected to the front end opening of the respiratory tube 150, and different respiratory impedance values can be simulated by replacing different respiratory impedance simulators 140 or setting the caliber of the respiratory impedance simulators 140. The impedance value Z1 of the integrated respiratory filter 130, the impedance value Z2 of the air duct of the integrated air duct system and the impedance value Z3 simulated by the respiratory impedance simulator 140 can obtain an integrated impedance value, and the respiratory impedance value of different types of patients can be simulated by adjusting the respiratory impedance simulator 140 to indirectly adjust the integrated impedance value. If the aperture size of the respiratory impedance simulator 140 is adjusted, the comprehensive impedance value is set to simulate the situation of a patient with chronic obstructive pulmonary disease (chronic obstructive pulmonary disease, COPD), so as to simulate the respiratory condition of the patient with COPD, the result of the nebulized administration test can be more accurate.
The breathing tube 150 can adopt a metal tube body and push-pull rod structure, the push-pull rod can adopt a metal material, the breathing tube 150 is of variable volume, the breathing tube 150 can be operated to adjust any volume in a measuring range by operating the push-pull rod, the breathing condition of a human body is simulated, for example, when the push-pull rod is pulled, the volume of the breathing tube 150 is increased, the air pressure in the tube is reduced, and the outside air is simulated to be inhaled in the air suction process; when the push-pull rod is pushed, the volume of the breathing cylinder 150 is reduced, the air pressure in the cylinder is increased, and the process of exhaling is simulated to discharge air to the outside.
In the process of controlling the push-pull rod to simulate inhalation, the flowing gas generated by the air pump 110 passes through the atomizing cup 120 to generate atomized air flow, and the atomized air flow sequentially passes through the respiratory filter 130 and the respiratory impedance simulator 140 to enter the respiratory tube 150, so that the test process of atomized drug delivery is completed. In the process, part of the liquid medicine in the atomizing cup 120 is atomized, and the atomization amount can be determined by measuring the mass change of the atomizing cup 120 or the mass of the liquid medicine attached to the respiratory filter 130, so that the atomization rate of the atomizing pump formed by the air pump 110 and the atomizing cup 120 during atomization is determined.
Compared with the prior art, the embodiment of the application has the following main beneficial effects:
the atomization drug delivery simulation device provided by the embodiment of the application comprises an air pump 110, an atomization cup 120, a respiratory filter 130, a respiratory impedance simulator 140 and a respiratory tube 150, and all components are communicated through an air channel pipe. Wherein, the liquid medicine is placed in the atomizing cup 120, the breathing tube 150 is provided with a push-pull rod, and in the process of controlling the push-pull rod to simulate inhalation, the flowing gas generated by the air pump 110 generates atomized air flow after passing through the atomizing cup 120, and the atomized air flow sequentially passes through the breathing filter 130 and the breathing impedance simulator 140 and then enters the breathing tube 150. The respiratory filter 130 is provided with an adsorption device, and the adsorption device can adsorb atomized liquid medicine and water vapor in the gas, so that the atomized liquid medicine is prevented from entering the respiratory tube 150. Therefore, the atomization drug administration simulation device can simulate the breathing process of a human body, and replaces a tester to perform atomization drug administration test.
In some possible implementations, as shown in fig. 2, fig. 2 is a schematic diagram of another embodiment of an aerosolized drug delivery simulation device provided in an embodiment of the present application, where the aerosolized drug delivery device further includes a control module 160, and the control module 160 is electrically connected to the air pump 110.
In embodiments of the present application, the aerosolized drug delivery device may further include a control module 160, which control module 160 may employ a micro-control unit (microcontroller unit, MCU) or field programmable gate array (field programmable gate array, FPGA) chip, or other types of control modules 160 or control chips, etc. The control module 160 is in communication with the air pump 110. In performing the nebulization test, a given flow value may be set to the air pump 110 by the control module 160, so that the air pump 110 outputs a given flow value of the flowing gas to the nebulizer.
In some possible implementations, the atomized medicine feeding device further includes a control module 160, a solenoid valve 170 is further disposed on the air path between the air pump 110 and the atomizing cup 120, and the control module 160 is electrically connected with the solenoid valve 170.
In the embodiment of the present application, the aerosolized drug delivery device may further include a control module 160, where the control module 160 may employ an MCU chip or an FPGA chip, or other types of control modules 160 or control chips, etc. An electromagnetic valve 170 can be further arranged in the middle of the air path between the air pump 110 and the atomizing cup 120, the electromagnetic valve 170 is in communication connection with the control module 160, and the control module 160 can be utilized to control the running state of the electromagnetic valve 170, so that the conduction state of the air path is controlled. For example, during simulated inhalation, solenoid valve 170 is opened to allow the air path to be opened, so that inhalation cartridge 150 can inhale the aerosolized medicament for aerosolized drug delivery testing.
In some possible implementations, the atomizing cup 120 further includes a mass detection module electrically connected to the control module 160 for detecting the mass of the atomizing cup 120.
In this embodiment of the present application, the atomizing cup 120 may further include a quality detection module, where the quality detection module may be in communication connection with the control module 160, and the quality detection module may detect the quality of the atomizing cup 120, obtain the quality variation condition of the atomizing cup 120 in the process of atomization administration test, and report the quality variation condition to the control module 160, so as to determine the atomization dosage, and further determine the atomization rate of the atomizing pump according to the atomization dosage.
In some possible implementations, a control module is disposed on the push-pull rod, the control module 160 is electrically connected to the control module, and the control module 160 is configured to control the push-pull rod by using the control module.
In this embodiment of the present application, the push-pull rod may further be provided with a control module to control the movement of the push-pull rod, for example, a driving motor may be connected to the push-pull rod, and the movement of the push-pull rod is driven and controlled by the driving motor. The control module can be in communication connection with the control module 160, so that the control module 160 can utilize the control module to control the movement of the push-pull rod, and the accurate control of the exhalation and inhalation processes of the exhalation tube 150 can be realized.
In some possible implementations, a flow sensor may be further disposed on the gas path between the atomizing cup and the respiratory filter, and the control module is electrically connected with the flow sensor.
In embodiments of the present application, a flow sensor may be disposed in the gas path between the atomizing cup 120 and the respiratory filter 130, which may be an electrochemical sensor, an ultrasonic sensor, or other types of flow sensors. The flow sensor may detect the flow of nebulized gas output by nebulizing cup 120 to respiratory filter 130, determine the volume of nebulized gas over a period of time, and report to the control module. Because of the differences between the different air pumps 110 or the atomizing cups 120, the amount of the administered air corresponding to the different actually measured atomizing gas volumes may be different. For this purpose, the first correspondence between the nebulized gas volume and the corresponding drug dose may be fitted according to the range of the drug dose contained in the nebulizing cup 120 by actually measuring the nebulized gas volume corresponding to the drug dose in the system, for example, how many grams of drug dose are corresponding to the 1L nebulized gas volume, how many grams of drug dose are corresponding to the 2L nebulized gas volume, how many grams of drug dose are corresponding to the 3L nebulized gas volume, and so on. The first correspondence may be different when the characteristics of the atomizing cup 120 and the air pump 110 are different. By measuring the first correspondence, the atomized gas volume is obtained, and then converted into a drug dose according to the first correspondence. And it should be noted that, the higher the requirement on calculating the dosage accuracy of the medicine, the higher the accuracy on calculating the volume of the atomized gas, and correspondingly, the higher the sampling frequency of the flow. Therefore, the high flow sampling frequency can be set as much as possible within the allowable range to improve the accuracy.
It is apparent that the embodiments described above are only some embodiments of the present application, but not all embodiments, the preferred embodiments of the present application are given in the drawings, but not limiting the patent scope of the present application. This application may be embodied in many different forms, but rather, embodiments are provided in order to provide a more thorough understanding of the present disclosure. Although the present application has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing, or equivalents may be substituted for elements thereof. All equivalent structures made by the specification and the drawings of the application are directly or indirectly applied to other related technical fields, and are also within the protection scope of the application.
Claims (6)
1. An aerosolized drug delivery simulation device, comprising:
the device comprises an air pump, an atomizing cup, a breathing filter, a breathing impedance simulator and a breathing tube;
the air pump, the atomizing cup, the breathing filter, the breathing impedance simulator and the breathing cylinder are connected through an air path pipe in sequence;
the liquid medicine is placed in the atomizing cup, a push-pull rod is arranged on the breathing tube, in the process of controlling the push-pull rod to simulate inhalation, flowing gas generated by the air pump passes through the atomizing cup to generate atomized air flow, and the atomized air flow sequentially passes through the breathing filter and the breathing impedance simulator to enter the breathing tube;
the respiratory filter is provided with an adsorption device, and the adsorption device is used for adsorbing atomized liquid medicine and water vapor in the atomized airflow.
2. The aerosolized drug delivery simulation device of claim 1, further comprising a control module, wherein the control module is electrically connected to the air pump.
3. The atomized drug delivery simulator of claim 1, further comprising a control module, wherein an electromagnetic valve is further arranged on the air path between the air pump and the atomizing cup, and the control module is electrically connected with the electromagnetic valve.
4. A nebulized drug delivery simulation device according to claim 2 or 3, wherein the nebulized cup further comprises a mass detection module, the mass detection module being electrically connected to the control module, the mass detection module being adapted to detect the mass of the nebulized cup.
5. An atomized drug delivery simulation device according to claim 2 or 3, wherein a control module is arranged on the push-pull rod, the control module is electrically connected with the control module, and the control module is used for controlling the push-pull rod by using the control module.
6. The aerosolized drug delivery simulation device of claim 2 or 3, wherein a flow sensor is further disposed on the gas path between the aerosolizing cup and the respiratory filter, and the control module is electrically connected to the flow sensor.
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CN202321684232.4U CN220530462U (en) | 2023-06-29 | 2023-06-29 | Atomization drug administration simulation device |
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CN202321684232.4U CN220530462U (en) | 2023-06-29 | 2023-06-29 | Atomization drug administration simulation device |
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