CN220443852U - Liquid separating device - Google Patents
Liquid separating device Download PDFInfo
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- CN220443852U CN220443852U CN202321950378.9U CN202321950378U CN220443852U CN 220443852 U CN220443852 U CN 220443852U CN 202321950378 U CN202321950378 U CN 202321950378U CN 220443852 U CN220443852 U CN 220443852U
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- liquid separation
- liquid
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- separation tube
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- 238000000926 separation method Methods 0.000 claims abstract description 159
- 238000001802 infusion Methods 0.000 claims description 9
- 230000002209 hydrophobic effect Effects 0.000 claims description 3
- 230000004044 response Effects 0.000 abstract description 9
- 238000012546 transfer Methods 0.000 abstract description 6
- 239000007921 spray Substances 0.000 abstract description 5
- 230000005284 excitation Effects 0.000 description 9
- 239000003153 chemical reaction reagent Substances 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 230000009471 action Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000032765 Device extrusion Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The embodiment of the utility model provides a liquid separating device, and relates to the technical field of liquid separation. The liquid separation device comprises a liquid separation tube body and a piezoelectric device, wherein the piezoelectric device is arranged on the liquid separation tube body, the piezoelectric device deforms under the condition of being electrified, the liquid separation tube body can be deformed, the shape of the liquid separation tube body can be changed through the piezoelectric device, for example, the liquid separation tube body is extruded to enable the liquid separation tube body to spray out liquid drops, or after the liquid separation tube body is pulled to deform, when the liquid separation tube body is restored to an initial state, the liquid separation function is realized, pneumatic liquid transfer in the prior art is replaced, a high-frequency valve and a compressed air source are not needed, the structure of the liquid separation device is simplified, the volume of the liquid separation device is reduced, the response rate of the piezoelectric device can reach tens of microseconds to a few milliseconds, and the liquid separation of other types of high-frequency and nano-grade is realized.
Description
Technical Field
The utility model relates to the technical field of liquid separation, in particular to a liquid separation device.
Background
In biochemical experiments, it is often necessary to accurately quantify minute amounts of liquid reagents or samples, so that accurate and rapid control of their split amounts is critical to the success of the experiment. In the experimental process, the laboratory workers need to utilize highly advanced and precise instruments, such as pipettes, automatic sample processing systems and the like, to realize accurate and high-speed liquid separation of trace liquid.
In the prior art, a pneumatic liquid separation method adopted by high-speed quantitative liquid separation can realize the distribution of micro liter and sub micro liter liquid reagents or samples, but pneumatic liquid transfer relies on a high-frequency valve and a compressed air source, so that the whole liquid separation device has higher complexity and larger volume, and cannot realize the liquid separation requirement of nano-upgrading due to the limitation of valve opening time.
Disclosure of Invention
The utility model provides a liquid separating device, which can simplify the structure of the liquid separating device, reduce the volume of the liquid separating device and realize nano-liter liquid separation.
Embodiments of the utility model may be implemented as follows:
the utility model provides a liquid separation device, comprising:
a liquid separation pipe body; and
and the piezoelectric device is arranged on the liquid separation pipe body.
In an alternative embodiment, the piezoelectric device is of an annular structure, and the piezoelectric device is sleeved on the outer wall of the liquid separation pipe body.
In an alternative embodiment, the piezoelectric device is in an arc structure, and the piezoelectric device surrounds the outer wall of the liquid separation pipe body along the axis of the liquid separation pipe body.
In an alternative embodiment, the piezoelectric device is fixedly connected to the outer wall of the liquid separation tube body.
In an alternative embodiment, the inner wall of the liquid separation tube body is provided with a hydrophobic layer.
In an alternative embodiment, the liquid separation device further comprises an adjustable voltage source, and the adjustable voltage source is electrically connected with the piezoelectric device.
In an alternative embodiment, the liquid separating device further comprises a liquid container and a liquid delivering pipeline, wherein the liquid container is communicated with a liquid inlet of the liquid delivering pipeline, and a liquid outlet of the liquid delivering pipeline is communicated with the liquid separating pipeline body.
In an optional embodiment, the liquid separation device further comprises a connector, and the liquid outlet of the infusion pipeline is communicated with the liquid separation pipe body through the connector.
In an alternative embodiment, the liquid separation device further comprises a liquid separation controller, and the liquid separation controller is electrically connected with the piezoelectric device.
In an alternative embodiment, the liquid separation device further comprises a temperature sensor, the temperature sensor is arranged on the outer wall of the liquid separation tube body, and the temperature sensor is electrically connected with the liquid separation controller.
The liquid separation device provided by the embodiment of the utility model has the beneficial effects that:
the utility model provides a liquid separation device, which comprises a liquid separation tube body and a piezoelectric device, wherein the piezoelectric device is arranged on the liquid separation tube body, the piezoelectric device deforms under the condition of electrifying, so that the liquid separation tube body can be deformed, and the shape of the liquid separation tube body can be changed through the piezoelectric device, for example, the liquid separation tube body is extruded to spray liquid drops, or after the liquid separation tube body is pulled to deform, the liquid separation tube body is enabled to spray liquid drops when the liquid separation tube body is restored to an initial state, so that the liquid separation function is realized, the pneumatic liquid transfer in the prior art is replaced, a high-frequency valve and a compressed air source are not needed, the structure of the liquid separation device is simplified, the volume of the liquid separation device is reduced, the response speed of the piezoelectric device can reach the level of tens of microseconds to several milliseconds, and the liquid separation of high-frequency and nano-level is realized.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present utility model and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of a liquid separation device provided in an embodiment of the present utility model;
FIG. 2 is a schematic view of a piezoelectric device extrusion liquid separation tube provided in an embodiment of the present utility model;
FIG. 3 is a schematic diagram of a power supply excitation signal output by an adjustable voltage source according to an embodiment of the present utility model;
FIG. 4 is a schematic diagram of a piezoelectric device pulling a liquid separation tube provided in an embodiment of the present utility model;
fig. 5 is a first cross-sectional view of a piezoelectric device having a ring structure provided in an embodiment of the present utility model sleeved on a liquid separation tube;
fig. 6 is a second cross-sectional view of the piezoelectric device of the ring structure provided in the embodiment of the present utility model sleeved on the liquid separation tube body;
FIG. 7 is a first cross-sectional view of a piezoelectric device having an arc structure according to an embodiment of the present utility model sleeved on a liquid separation tube;
fig. 8 is a second cross-sectional view of the piezoelectric device with the arc structure provided in the embodiment of the utility model sleeved on the liquid separation pipe body.
Icon: 100-liquid separation pipe body; 200-piezoelectric devices; 300-an adjustable voltage source; 400-liquid container; 500-transfusion pipeline; 600-connecting head; 700-a liquid separation controller; 800-a temperature sensor; 10-droplets; 20-liquid.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments of the present utility model. The components of the embodiments of the present utility model generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the utility model, as presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
In the description of the present utility model, it should be noted that, if the terms "upper", "lower", "inner", "outer", and the like indicate an azimuth or a positional relationship based on the azimuth or the positional relationship shown in the drawings, or the azimuth or the positional relationship in which the inventive product is conventionally put in use, it is merely for convenience of describing the present utility model and simplifying the description, and it is not indicated or implied that the apparatus or element referred to must have a specific azimuth, be configured and operated in a specific azimuth, and thus it should not be construed as limiting the present utility model.
Furthermore, the terms "first," "second," and the like, if any, are used merely for distinguishing between descriptions and not for indicating or implying a relative importance.
It should be noted that the features of the embodiments of the present utility model may be combined with each other without conflict.
As mentioned in the background, in biochemical experiments, it is often necessary to accurately quantify minute amounts of liquid reagents or samples, so that accurate and rapid control of their split amounts is critical to the success of the experiment. In the experimental process, the laboratory workers need to utilize highly advanced and precise instruments, such as pipettes, automatic sample processing systems and the like, to realize accurate and high-speed liquid separation of trace liquid.
By the technical means, a large amount of samples can be processed in a short time, so that the research is rapidly advanced. In summary, quantifying and high-speed pipetting of minute amounts of liquid reagents or samples in biochemical experiments is a critical technique that is of great importance for research progress and reproducibility and reliability of experimental data.
In the prior art, a pneumatic liquid separation method adopted by high-speed quantitative liquid separation can realize the distribution of micro liter and sub micro liter liquid reagents or samples, but pneumatic liquid transfer relies on a high-frequency valve and a compressed air source, so that the whole liquid separation device has higher complexity and larger volume, and cannot realize the liquid separation requirement of nano-upgrading due to the limitation of valve opening time.
Specifically, the switching time depends on the response speed of the electromagnet, the valve structure and other factors, and can only realize millisecond level, and the accurate switching valve control of microsecond level is difficult to realize, so that the nano-upgrading liquid separation requirement cannot be realized.
In view of this, please refer to fig. 1-8, a liquid separating device according to an embodiment of the present utility model can solve this problem, and a detailed description will be given below.
Referring to fig. 1, in an embodiment of the present utility model, a liquid separation device is provided, where the liquid separation device includes a liquid separation tube 100 and a piezoelectric device 200, and the piezoelectric device 200 is disposed on the liquid separation tube 100, where the piezoelectric device 200 deforms under the condition of being electrified, so that the liquid separation tube 100 can be deformed.
Since the shape of the liquid separation tube body 100 can be changed through the piezoelectric device 200, for example, the liquid separation tube body 100 is extruded, so that the liquid drop 10 is sprayed out of the liquid separation tube body 100, or after the liquid separation tube body 100 is pulled to deform, when the liquid separation tube body 100 is restored to an initial state, the liquid separation tube body 100 is enabled to spray out the liquid drop 10, so that the liquid separation function is realized, pneumatic liquid transfer in the prior art is replaced, a high-frequency valve and a compressed air source are not needed, the structure of the liquid separation device is simplified, the volume of the liquid separation device is reduced, the response rate of the piezoelectric device 200 can reach the level of tens of microseconds to several milliseconds, and the liquid separation of high-frequency and nano-grade types is realized.
In this embodiment, the piezoelectric device 200 may be a piezoelectric ceramic device, so that a response rate of tens of microseconds to several milliseconds may be achieved, which not only may realize micro-liter level liquid separation control, but also may realize nano-level liquid separation requirements.
With continued reference to fig. 2 and 3, for convenience in powering the piezoelectric device 200, the liquid separation apparatus further includes an adjustable voltage source 300, where the adjustable voltage source 300 is electrically connected to the piezoelectric device 200, and the adjustable voltage source 300 may provide a power excitation signal as shown in fig. 3.
As can be seen from fig. 3, the voltage (volt) increases with time (T), then stabilizes and finally decreases, the time of the entire excitation signal for supplying power to the piezoelectric device 200 is T, and the voltage supplied to the piezoelectric device 200 is V 1 。
In fig. 2, the adjustable voltage source 300 outputs the power excitation signal in fig. 3, the piezoelectric device 200 deforms, the compression deformation acts on the outer wall of the pipeline, and the liquid separation pipe 100 is extruded to deform, specifically, the liquid separation pipe 100 is extruded along the radial direction of the liquid separation pipe 100, and the liquid 20 in the liquid separation pipe 100 has incompressibility, so that the liquid drop 10 is ejected from the liquid outlet end of the liquid separation pipe 100 under the action of pressure.
Then, in the voltage drop stage of the whole excitation signal, the piezoelectric device 200 is restored to the initial state, the deformation of the liquid separation tube 100 is restored, and the liquid 20 is replenished to the liquid inlet end of the liquid separation tube 100 under the action of air pressure.
It should be noted that, in this embodiment, the liquid separation tube 100 is a flexible tube, the inner wall of the liquid separation tube 100 is provided with a hydrophobic layer, such as a Teflon (Teflon) coating, and the port caliber of the liquid outlet end of the liquid separation tube 100 is smaller than the port caliber of the liquid inlet end of the liquid outlet tube.
Of course, in other embodiments, referring to fig. 4, the liquid droplet 10 may be ejected from the liquid outlet end of the liquid separation tube 100 by pulling the liquid separation tube 100.
Specifically, when the adjustable voltage source 300 outputs a power supply excitation signal as shown in fig. 3, the piezoelectric device 200 deforms, the piezoelectric device 200 pulls the outer wall of the liquid separation tube 100 along the radial direction of the liquid separation tube 100, a negative pressure is generated in the liquid separation tube 100, under the action of the negative pressure, the liquid inlet end of the liquid separation tube 100 enters the liquid 20, and in the stage of voltage drop in the whole excitation signal, the piezoelectric device 200 returns to the initial state, and because the liquid 20 has incompressibility, more liquid 20 in the liquid separation tube 100 is ejected from the liquid outlet end of the liquid separation tube 100.
It should be noted that, in order to facilitate pulling or extruding the outer wall of the liquid separation tube body 100, the piezoelectric device 200 is fixedly connected to the outer wall of the liquid separation tube body 100, for example, the piezoelectric device 200 may be connected to the outer wall of the liquid separation tube body 100 by an adhesive manner, so as to ensure that the liquid separation tube body 100 moves along with the piezoelectric device 200 during deformation or recovery of the piezoelectric device 200.
Of course, in other embodiments, the piezoelectric device 200 may be integrally formed with the liquid separation tube 100, so as to fixedly connect the piezoelectric device 200 to the outer wall of the liquid separation tube 100, so as to ensure that the liquid separation tube 100 moves along with the piezoelectric device 200 during deformation or recovery of the piezoelectric device 200.
The change in the volume of the liquid 20 discharged from the liquid-dividing pipe body 100, that is, the change in the deformation amount of the piezoelectric device 200, can be achieved by changing the deformation amount of the piezoelectric device 200, for example, the larger the deformation amount of the piezoelectric device 200 is, the larger the deformation amount of the liquid-dividing pipe body 100 is, the larger the volume of the liquid 20 discharged is, or the smaller the deformation amount of the piezoelectric device 200 is, the smaller the deformation amount of the liquid-dividing pipe body 100 is, and the smaller the volume of the liquid 20 discharged is.
Referring to fig. 1 again, in order to facilitate the supply of the liquid 20 to the liquid inlet end of the liquid dispensing tube 100, the liquid dispensing device further includes a liquid container 400 and an infusion tube 500, wherein the liquid container 400 is communicated with the liquid inlet of the infusion tube 500, and the liquid outlet of the infusion tube 500 is communicated with the liquid dispensing tube 100.
The liquid container 400 is used to store a liquid 20, and the liquid 20 may be a liquid reagent or a sample.
Meanwhile, in order to facilitate connection of the liquid container 400 and the liquid inlet of the infusion line 500, the liquid separation device further comprises a connector 600, and the liquid outlet of the infusion line 500 is communicated with the liquid separation tube 100 through the connector 600.
In addition, in order to conveniently control the power supply of the piezoelectric device 200 and realize the deformation or recovery of the piezoelectric device 200, the liquid separation device further comprises a liquid separation controller 700, and the liquid separation controller 700 is electrically connected with the piezoelectric device 200.
Meanwhile, in order to improve pipetting accuracy, the pipetting device further comprises a temperature sensor 800, the temperature sensor 800 is arranged on the outer wall of the pipetting tube 100, the temperature sensor 800 is electrically connected with the pipetting controller 700, and the temperature sensor 800 is used for detecting the tube wall temperature of the pipetting tube 100 so as to calibrate the control parameters of the piezoelectric device 200 and ensure the consistency of pipetting volumes at different working temperatures.
Specifically, in order to ensure consistency of the pipetting volumes due to the thermal expansion and contraction characteristics of the liquid, the control parameters of the piezoelectric device 200 may be adjusted under different temperatures, where the control parameters of the piezoelectric device 200 may be understood as the power supply excitation signal shown in fig. 3, and control of the piezoelectric device 200 is achieved by adjusting the duration or the maximum value of the voltage of the power supply excitation signal, so as to finally achieve consistency of the pipetting volumes under different working temperatures.
For example, the higher the temperature, the higher the liquid volume, the larger the voltage, so that the deformation amount of the piezoelectric device 200 is reduced, and the consistency of the pipetting volume is maintained.
When the temperature is lower, the liquid volume is reduced to a certain extent, and the maximum value of the voltage can be increased, so that the deformation of the piezoelectric device 200 is increased, and the consistency of the pipetting volume is maintained.
In addition, in order to facilitate the ejection of the liquid droplets 10 from the liquid separation tube 100, the piezoelectric devices 200 may be distributed in the radial direction of the liquid separation tube 100, and may be partially wrapped or fully wrapped.
Referring to fig. 5 and 6, the piezoelectric device 200 may have a ring structure, and the piezoelectric device 200 is sleeved on the outer wall of the liquid separation tube 100.
Referring to fig. 7 and 8, the piezoelectric device 200 may also have an arc structure, and the piezoelectric device 200 surrounds the outer wall of the liquid separation tube 100 along the axis of the liquid separation tube 100, for example, the piezoelectric device 200 has a semi-annular structure.
In summary, the liquid separation device includes the liquid separation tube 100 and the piezoelectric device 200, where the piezoelectric device 200 is disposed on the liquid separation tube 100, and the piezoelectric device 200 deforms under the condition of being electrified, so that the liquid separation tube 100 can be deformed.
Because the shape of the liquid separation tube body 100 can be changed through the piezoelectric device 200, for example, the liquid separation tube body 100 is extruded, so that the liquid drop 10 is sprayed out of the liquid separation tube body 100, or after the liquid separation tube body 100 is pulled to deform, when the liquid separation tube body is restored to an initial state, the liquid separation tube body 100 is enabled to spray out the liquid drop 10, the liquid separation function is realized, pneumatic liquid transfer in the prior art is replaced, a high-frequency valve and a compressed air source are not needed, the structure of the liquid separation device is simplified, the volume of the liquid separation device is reduced, the response rate of the piezoelectric device 200 can reach tens of microseconds to a few milliseconds, and the liquid separation of the high-frequency and nano-grade types is realized.
The response rate of the piezoelectric device 200 may reach tens of microseconds to several milliseconds, and a high-speed, high-precision and micro-scale liquid separation device is provided in the embodiment.
In addition, in the liquid separation operation of the liquid separation device, the only executive component is the piezoelectric device 200, and the response speed of the piezoelectric device 200 is high and can reach the level of tens of microseconds to several milliseconds, so that the liquid separation of high-frequency and nano-level grades can be realized.
In addition, the piezoelectric device 200 has good response repeatability, can realize the liquid separation function with high precision and repeatability, does not need to depend on a high-frequency valve and a compressed air source, has a simple structure and a small volume, and realizes the liquid separation function with high speed, high precision and other nano-level.
The foregoing is merely illustrative of the present utility model, and the present utility model is not limited thereto, and any changes or substitutions easily contemplated by those skilled in the art within the scope of the present utility model should be included in the present utility model. Therefore, the protection scope of the present utility model shall be subject to the protection scope of the claims.
Claims (10)
1. A liquid separation device, comprising:
a liquid separation pipe body (100); and
and the piezoelectric device (200) is arranged on the liquid separation tube body (100).
2. The liquid separating device according to claim 1, wherein the piezoelectric device (200) has a ring-shaped structure, and the piezoelectric device (200) is sleeved on the outer wall of the liquid separating tube body (100).
3. The liquid separating device according to claim 1, wherein the piezoelectric device (200) has an arc-shaped structure, and the piezoelectric device (200) surrounds the outer wall of the liquid separating tube body (100) along the axis of the liquid separating tube body (100).
4. The liquid separation device according to claim 1, wherein the piezoelectric device (200) is fixedly connected to the outer wall of the liquid separation tube body (100).
5. The liquid separation device according to claim 1, characterized in that the inner wall of the liquid separation tube body (100) is provided with a hydrophobic layer.
6. The liquid separation device according to claim 1, further comprising an adjustable voltage source (300), the adjustable voltage source (300) being electrically connected to the piezoelectric device (200).
7. The liquid separation device according to claim 1, further comprising a liquid container (400) and an infusion line (500), wherein the liquid container (400) is in communication with a liquid inlet of the infusion line (500), and wherein a liquid outlet of the infusion line (500) is in communication with the liquid separation tube (100).
8. The liquid separation device according to claim 7, further comprising a connector (600), wherein the liquid outlet of the liquid delivery line (500) is communicated with the liquid separation tube body (100) through the connector (600).
9. The liquid separation device according to claim 1, further comprising a liquid separation controller (700), wherein the liquid separation controller (700) is electrically connected to the piezoelectric device (200).
10. The liquid separation device according to claim 9, further comprising a temperature sensor (800), wherein the temperature sensor (800) is arranged on an outer wall of the liquid separation tube body (100), and wherein the temperature sensor (800) is electrically connected to the liquid separation controller (700).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321950378.9U CN220443852U (en) | 2023-07-24 | 2023-07-24 | Liquid separating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321950378.9U CN220443852U (en) | 2023-07-24 | 2023-07-24 | Liquid separating device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220443852U true CN220443852U (en) | 2024-02-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321950378.9U Active CN220443852U (en) | 2023-07-24 | 2023-07-24 | Liquid separating device |
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| Country | Link |
|---|---|
| CN (1) | CN220443852U (en) |
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2023
- 2023-07-24 CN CN202321950378.9U patent/CN220443852U/en active Active
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