CN220424018U - Device is put into to mouse uterus medicine stick - Google Patents

Device is put into to mouse uterus medicine stick Download PDF

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Publication number
CN220424018U
CN220424018U CN202321974973.6U CN202321974973U CN220424018U CN 220424018 U CN220424018 U CN 220424018U CN 202321974973 U CN202321974973 U CN 202321974973U CN 220424018 U CN220424018 U CN 220424018U
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China
Prior art keywords
section
penetrating
rod
mouse
medicine
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CN202321974973.6U
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Chinese (zh)
Inventor
刘志勇
师伟
王信
石雅馨
曹涵
王子璐
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Affiliated Hospital of Shandong University of Traditional Chinese Medicine
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Affiliated Hospital of Shandong University of Traditional Chinese Medicine
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Abstract

The utility model relates to the technical field of medical equipment, in particular to a device for placing a mouse uterine drug rod, which comprises: a sleeve and a binding wire; the sleeve comprises a penetrating section, the end part of the penetrating section is provided with a spike part for penetrating the uterus of a mouse, the penetrating section is internally provided with a containing cavity, and the inner diameter of the containing cavity is larger than the outer diameter of the medicine rod; the binding wire penetrates through the medicine rod, two ends of the binding wire extend out of two ends of the medicine rod, and two ends of the binding wire can be bound on the uterus of a mouse to fix the medicine rod. The utility model solves the problem that the tough medicine stick is difficult to be placed into a soft uterus, and can fix the medicine stick at a specific position of the mouse uterus.

Description

Device is put into to mouse uterus medicine stick
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a device for placing a mouse uterine drug stick.
Background
The disclosure of this background section is only intended to increase the understanding of the general background of the utility model and is not necessarily to be construed as an admission or any form of suggestion that this information forms the prior art already known to those of ordinary skill in the art.
The intervention of the medicine stick into the uterus of the mice is an innovative experimental method, and certain diseases or symptoms are treated by putting the medicine stick or other substances into the uterus of the mice, so as to study the physiological and pathological changes of the uterus of the mice.
In the experiment, the medicine stick is put into the uterus of a mouse, and the medicine stick can release medicine in the uterus of the mouse for intervention. However, some medicine sticks have a tough texture, and the uterus of a mouse is soft, and the thickness of the medicine sticks is not different from that of the uterus of the mouse, so that the medicine sticks are difficult to put into the uterus of the mouse. In addition, the drug stick is not easy to fix at a specific position of the uterus after being put into the uterus of a mouse.
Disclosure of Invention
Aiming at the defects existing in the prior art, the embodiment of the utility model aims to provide a device for placing a medicine rod in a uterus of a mouse, so as to solve the problem that the tough medicine rod is difficult to place in the uterus of the mouse, and the medicine rod can be fixed at a specific position of the uterus of the mouse.
In order to achieve the above object, the embodiment of the present utility model provides the following technical solutions:
a mouse uterine drug stick placement device comprising: a sleeve and a binding wire; the sleeve comprises a penetrating section, the end part of the penetrating section is provided with a spike part for penetrating the uterus of a mouse, the penetrating section is internally provided with a containing cavity, and the inner diameter of the containing cavity is larger than the outer diameter of the medicine rod; the binding wire penetrates through the medicine rod, two ends of the binding wire extend out of two ends of the medicine rod, and two ends of the binding wire can be bound on the uterus of a mouse to fix the medicine rod.
Preferably, the sleeve further has a holding section connected with the penetrating section, the holding section and the penetrating section are both circular, and the outer diameter of the holding section is larger than the outer diameter of the penetrating section.
Preferably, the sleeve further has a transition section, the transition section is conical, the conical transition section is arranged between the holding section and the penetrating section, the first end of the transition section is connected with the holding section, and the second end of the transition section is connected with the penetrating section.
Preferably, the penetrating segment and the gripping segment are detachably connected.
Preferably, one side of the spike part is provided with an inclined plane, and the inclined plane and the axis of the penetrating section form an included angle of 15-20 degrees.
Preferably, the penetrating segment is made of metal.
Preferably, the inner diameter of the spike is 1.5mm and the length of the spike is 3mm.
Preferably, the device further comprises a push core, wherein the push core is provided with a push rod, and the end part of the push rod is provided with a spherical surface.
Preferably, a first baffle ring is arranged at one end of the sleeve, which is far away from the spike part, and a second baffle ring is arranged at one end of the push core, which is far away from the spherical surface.
Preferably, the binding wire is a surgical wire.
One or more technical solutions provided in the embodiments of the present utility model at least have the following technical effects or advantages:
the medicine rod is smoothly placed into the uterus of the mouse through the sleeve of the placement device, the problem that the flexible medicine rod is difficult to place into the soft uterus is solved, the binding wires at the two ends of the medicine rod are used for knotting, the medicine rod is ensured to be fixed at a specific position of the uterus of the mouse, and the optimal treatment effect is realized.
Additional aspects of the utility model will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the utility model.
In order to make the above objects, features and advantages of the present utility model more comprehensible, preferred embodiments accompanied with figures are described in detail below.
Drawings
The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the utility model.
FIG. 1 is a schematic diagram of a mouse uterine configuration;
FIG. 2 is a schematic illustration of a solid drug stick according to an embodiment of the present utility model mounted in a cannula;
FIG. 3 is a schematic illustration of a sleeve and push core provided by an embodiment of the present utility model;
fig. 4 is a schematic view of a binding-wire-embedded drug rod according to an embodiment of the present utility model;
FIG. 5 is a schematic illustration of an implant device according to an embodiment of the present utility model penetrating a mouse uterus;
FIG. 6 is a schematic illustration of a drug stick according to an embodiment of the present utility model being secured in a mouse uterus;
in the figure: 1. a sleeve; 11. a grip section; 12. a transition section; 13. a penetration section; 14. a spike; 15. a first baffle ring; 2. pushing the core; 21. a push rod; 22. a second baffle ring; 3. binding wires; 4. a medicine stick; 5. uterus of mice; 51. uterine horns; 52. a uterine body; 53. a cervix;
the mutual spacing or dimensions are exaggerated for the purpose of showing the positions of the various parts, and the schematic illustrations are used for illustration only.
Detailed Description
It should be noted that the following detailed description is illustrative and is intended to provide further explanation of the utility model. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the present utility model. As used herein, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the utility model clearly indicates otherwise, and it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.
The mouse is a mammal, the gene is similar to human, the reproductive capacity is strong, the placenta type is very similar to human, and the mouse modeling is more scientific, so the mouse becomes an experimental material for reproductive medicine research.
As shown in fig. 1, the construction of the mouse uterus 5 is described: the livestock uterus is divided into three parts, namely a uterine horn 51, a uterine body 52 and a cervix 53. From the anterior end of the cervix 53 to the base of the uterus is the uterus 52. The anterior end of the cervix 53 is in communication with the uterus 52 and the posterior end protrudes into the vagina, referred to as the vaginal portion of the cervix 53. The tissue structure is serosa, myolayer and mucous membrane from outside to inside.
The medicine rod 4 is a medicine-containing solid rod, and the medicine rod 4 is placed into the uterus 5 of the mouse to directly act on the uterus 5 of the mouse, so that the therapeutic effect is achieved. Because some medicine sticks 4 are tough in texture and the mouse uterus 5 is soft in texture, and the thickness of the medicine sticks 4 is not very different from that of the mouse uterus 5, the medicine sticks 4 are difficult to put into the mouse uterus 5, and the medicine sticks 4 are not easy to fix at specific positions of the uterus. In order to solve the technical problems, the utility model provides a device for placing a medicine rod 4 into a mouse uterus 5.
As shown in fig. 2-4, in one embodiment of the present utility model, a device for inserting a medicine stick 4 into a uterus 5 of a mouse is provided, comprising: a sleeve 1 and a binding wire 3; the sleeve 1 comprises a penetrating section 13, a spike part 14 for penetrating the uterus 5 of a mouse is arranged at the end part of the penetrating section 13, a containing cavity is arranged in the penetrating section 13, and the inner diameter of the containing cavity is larger than the outer diameter of the medicine rod 4; the binding wire 3 penetrates through the medicine rod 4, two ends of the binding wire 3 protrude out of two ends of the medicine rod 4, and two ends of the binding wire 3 can be bound on the uterus 5 of the mouse to fix the medicine rod 4.
The sleeve 1 is a hollow sleeve 1 with a harder tip, the medicine rod 4 is a medicine-containing solid rod, the binding wire 3 is an operation wire (absorbable) embedded in the middle of the medicine rod 4, as shown in fig. 4, the position of the solid rod can be adjusted by pulling the binding wire 3, and after the solid rod is placed into the uterus 5 of a mouse, both ends of the operation wire can be knotted, so that the fixing effect is achieved.
When in use, the solid stick is put into the sleeve 1, as shown in figure 2, the spike part 14 of the sleeve 1 penetrates through the uterine wall to enter the cavity, the sleeve 1 is slowly moved forward to enable the traditional Chinese medicine stick 4 to enter a fixed position on one side of the uterus, then the sleeve 1 is continuously pushed forward, the spike part 14 penetrates through the uterine wall, the binding wire 3 is pulled on the opposite side to slowly withdraw the sleeve 1, the medicine stick 4 is remained in the uterus 5 of a mouse, the binding wires 3 at two ends of the medicine stick 4 are used for knotting, and the position of the medicine stick 4 is fixed.
Therefore, the medicine rod 4 is smoothly placed into the uterus 5 of the mouse through the sleeve 1 of the placement device, the problem that the flexible medicine rod 4 is difficult to place into the soft uterus is solved, the binding wires 3 at the two ends of the medicine rod 4 are used for knotting, the medicine rod 4 is ensured to be fixed at a specific position of the uterus 5 of the mouse, and the optimal treatment effect is realized.
Since the penetrating portion pierces the uterus 5 of the mouse, the diameter of the penetrating portion is generally small, which makes it difficult for a worker to hold the sleeve 1, and therefore, the sleeve 1 of the present utility model further has a holding section 11, as shown in fig. 3, the holding section 11 is connected to the penetrating section 13, the holding section 11 and the penetrating section 13 are both circular, and the outer diameter of the holding section 11 is larger than the outer diameter of the penetrating section 13. Through setting up the great section of gripping 11 of diameter, make things convenient for the staff to hold between the fingers, improved the simple operation nature.
Further, the sleeve 1 further has a transition section 12, the transition section 12 is conical, the conical transition section 12 is disposed between the holding section 11 and the penetrating section 13, the diameter of the first end of the transition section 12 is the same as and connected to the diameter of the holding section 11, and the diameter of the second end of the transition section 12 is the same as and connected to the diameter of the penetrating section 13. The sleeve 1 of this embodiment connects the holding section 11 and the penetrating section 13 through the middle conical transition section 12, and is convenient to place the medicine rod 4 into the penetrating section 13, avoiding the medicine rod 4 to be clamped in the middle, and in addition, being beneficial to pushing the inner pushing core 2.
As shown in fig. 3, one side of the spike 14 of the penetrating segment 13 has an inclined plane, and the inclined plane forms an angle of 15-20 degrees with the axis of the penetrating segment 13, so as to facilitate the penetrating part to smoothly penetrate into the uterus 5 of the mouse and penetrate.
It can be appreciated that the penetrating section 13 and the holding section 11 may be an integral structure, or the penetrating section 13 and the holding section 11 may be a separate structure, and the penetrating section 13 and the holding section 11 may be detachably connected by threads or plugging.
When the penetrating segment 13 and the holding segment 11 are in a split structure, the penetrating segment 13 is made of metal, such as stainless steel 304 or 316L, and the two materials have the advantages of strong hardness, tough texture, high elasticity, and difficult corrosion. The grip section 11 may be made of medical non-toxic transparent soft polyvinyl chloride plastic or high performance polyolefin thermoplastic elastomer (TPE) material.
Further, the inner diameter of the spike 14 is 1.5mm, and the length of the spike 14 is 3mm.
The device for placing the medicine sticks 4 in the uterus 5 of the mouse further comprises a pushing core 2, as shown in fig. 3, the pushing core 2 is provided with a pushing rod 21, the end part of the pushing rod 21 is provided with a spherical surface, and the medicine sticks 4 are conveniently pushed out of the penetrating section 13 of the sleeve 1 through the arrangement of the pushing core 2. Through the cooperation of pushing end sphere and sleeve 1 conical transition section 12, prevent to take place the jamming when pushing, guarantee to push away core 2 and can pour into penetrating segment 13 smoothly and then promote medicine stick 4.
Further, a first baffle ring 15 is arranged at one end of the sleeve 1 far away from the spike part 14, a second baffle ring 22 is arranged at one end of the push core 2 far away from the spherical surface, and the push core 2 is convenient to move relative to the sleeve 1 through the arrangement of the first baffle ring 15 and the second baffle ring 22.
The using process of the imbedding device comprises the following steps:
firstly, a solid rod is placed into a sleeve 1, as shown in fig. 2, a spike part 14 of the sleeve 1 penetrates through the uterine wall to enter a cavity gap, the sleeve 1 is slowly moved forward to enable a traditional Chinese medicine rod 4 to enter a fixed position on one side of the uterus, then the sleeve 1 is continuously pushed forward, the spike part 14 penetrates through the uterine wall, as shown in fig. 5, a binding wire 3 is pulled on the opposite side of a mouse uterus 5 with the aid of a pushing core 2 to slowly withdraw the sleeve 1, the medicine rod 4 is remained in the mouse uterus 5, and then the binding wires 3 at two ends of the medicine rod 4 are used for knotting, so that the medicine rod 4 is fixed, as shown in fig. 6.
While the foregoing description of the embodiments of the present utility model has been presented in conjunction with the drawings, it should be understood that it is not intended to limit the scope of the utility model, but rather, it is intended to cover all modifications or variations within the scope of the utility model as defined by the claims of the present utility model.

Claims (9)

1. A mouse uterine drug stick placement device, comprising: a sleeve and a binding wire;
the sleeve comprises a penetrating section, the end part of the penetrating section is provided with a spike part for penetrating the uterus of a mouse, the penetrating section is internally provided with a containing cavity, and the inner diameter of the containing cavity is larger than the outer diameter of the medicine rod;
the binding wire penetrates through the medicine rod, two ends of the binding wire extend out from two ends of the medicine rod, and the two ends of the binding wire can be bound on the uterus of the mouse to fix the medicine rod;
the medicine rod pushing device is characterized by further comprising a pushing core, the pushing core is provided with a pushing rod, the end part of the pushing rod is provided with a spherical surface, and the pushing core is used for pushing out the medicine rod from the penetrating section of the sleeve.
2. The device of claim 1, wherein the sleeve further comprises a grip section, the grip section is connected to the penetrating section, the grip section and the penetrating section are both circular, and an outer diameter of the grip section is greater than an outer diameter of the penetrating section.
3. The mouse uterine drug rod placement device of claim 2, wherein the sleeve further has a transition section, the transition section being conical, the conical transition section being disposed between the grip section and the penetration section, the transition section first end being connected to the grip section, the transition section second end being connected to the penetration section.
4. The mouse uterine drug rod placement device of claim 2, wherein the penetrating segment and the gripping segment are detachably connected.
5. The device for inserting a mouse uterine drug stick according to claim 1, wherein one side of the spike is provided with an inclined plane, and an included angle between the inclined plane and the axis of the penetrating segment is 15-20 degrees.
6. The device of claim 5, wherein the penetrating segment is metallic.
7. The mouse uterine drug rod placement device of claim 1, wherein the inner diameter of the spike is 1.5mm and the length of the spike is 3mm.
8. The mouse uterine drug rod placement device of claim 1, wherein a first baffle ring is disposed at an end of the sleeve distal to the spike, and a second baffle ring is disposed at an end of the push core distal to the sphere.
9. The mouse uterine drug rod placement device of claim 1, wherein the binding wire is a surgical wire.
CN202321974973.6U 2023-07-25 2023-07-25 Device is put into to mouse uterus medicine stick Active CN220424018U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202321974973.6U CN220424018U (en) 2023-07-25 2023-07-25 Device is put into to mouse uterus medicine stick

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202321974973.6U CN220424018U (en) 2023-07-25 2023-07-25 Device is put into to mouse uterus medicine stick

Publications (1)

Publication Number Publication Date
CN220424018U true CN220424018U (en) 2024-02-02

Family

ID=89693425

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202321974973.6U Active CN220424018U (en) 2023-07-25 2023-07-25 Device is put into to mouse uterus medicine stick

Country Status (1)

Country Link
CN (1) CN220424018U (en)

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