CN220405589U - Integrated device for magnetic bead production - Google Patents
Integrated device for magnetic bead production Download PDFInfo
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- CN220405589U CN220405589U CN202321443468.9U CN202321443468U CN220405589U CN 220405589 U CN220405589 U CN 220405589U CN 202321443468 U CN202321443468 U CN 202321443468U CN 220405589 U CN220405589 U CN 220405589U
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- control panel
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- 239000011324 bead Substances 0.000 title claims abstract description 41
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 35
- 238000003756 stirring Methods 0.000 claims abstract description 49
- 238000006243 chemical reaction Methods 0.000 claims abstract description 31
- 230000002572 peristaltic effect Effects 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 238000002604 ultrasonography Methods 0.000 claims description 4
- 230000005540 biological transmission Effects 0.000 claims description 3
- 238000013019 agitation Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000006555 catalytic reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000008204 material by function Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- -1 polytetrafluoroethylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The utility model discloses an integrated device for magnetic bead production, which is characterized by comprising a reactor main box, a reaction kettle (701) which is assembled on the reactor main box and is provided with a feed inlet (702), a stirring assembly, an ultrasonic assembly, a temperature control assembly, a feed assembly and a power switch (801); the stirring assembly is assembled above the reaction kettle (701); the feeding component is connected with the reaction kettle (701); the ultrasonic assembly, the temperature control assembly, the stirring assembly and the feeding assembly are all in circuit connection with the power switch (801). The integrated device for magnetic bead production disclosed by the utility model can simultaneously realize multiple functions in the magnetic bead production process, is simple and convenient to operate, and ensures the stability among magnetic bead batches.
Description
Technical Field
The utility model belongs to the technical field of magnetic bead production, and particularly relates to an integrated device for magnetic bead production.
Background
With the development of nano science and technology, the nano magnetic beads have great application prospects in the fields of chemical industry, biology, medicine, catalysis, environmental protection, spinning, aerospace, cultural relics protection and the like due to the remarkable surface and volume effects and the characteristic of controllable movement under an external magnetic field. Particularly, as researchers carry out surface modification on different nano magnetic beads, a plurality of biological functional materials are prepared and widely applied to the biomedical fields of pathology, physiology, pharmacology, microorganism, biochemistry, molecular genetics and the like. The requirements on the quantity and the quality of the nano magnetic beads are increasingly strict, so that how to realize the efficient, batch and automatic stable production of the nano magnetic beads is the research focus in the fields of materials and biological medicines at present.
In the production reaction process of the current nanometer magnetic beads, the simultaneous processing of functions such as ultrasonic, stirring, sample adding and temperature control is involved, however, the existing equipment cannot realize simultaneous performance of a plurality of functions, the operation process is complex and time-consuming, the production efficiency of the magnetic beads is greatly reduced, excessive instruments and equipment occupy a production workshop, the waste of manpower and space is caused, and the cost is also greatly increased.
Disclosure of Invention
The utility model aims to provide an integrated device for magnetic bead production.
The utility model provides an integrated device for magnetic bead production, which comprises a reactor main box, a reaction kettle (701) which is assembled on the reactor main box and is provided with a feed inlet (702), a stirring assembly, an ultrasonic assembly, a temperature control assembly, a feed assembly and a power switch (801); the stirring assembly is assembled above the reaction kettle (701); the feeding component is connected with the reaction kettle (701); the ultrasonic assembly, the temperature control assembly, the stirring assembly and the feeding assembly are all in circuit connection with the power switch (801).
Preferably, the main tank of the reactor is surrounded by a first side plate (401), a second side plate (403), a third side plate (404), a fourth side plate and a first bottom plate (402) to form a tank structure with one open surface; -a base (902) is secured to the top of the first base plate (402); the reaction kettle (701) is fixed at the top of the base (902); the temperature control assembly comprises a compressor unit (603), a temperature sensor (602) and a temperature control panel (601); the temperature control panel (601) is assembled on the outer wall of the second side plate (403); the temperature sensor (602) is assembled on the inner wall of the fourth side plate; the unit (603) is arranged on the inner wall of the first side plate (401); the temperature control panel (601) is respectively connected with the unit (603), the temperature sensor (602) and the power switch (801) in a circuit mode.
Preferably, the stirring assembly comprises a stirring paddle (102), an adjustable stirring paddle chuck (103) and a stirring control panel (101); the top of the stirring paddle (102) is in transmission connection with the adjustable stirring paddle chuck (103), and the other end of the stirring paddle is arranged in the reaction kettle (701); the adjustable stirring paddle chuck (103) is arranged above the reaction kettle (701); the stirring control panel (101) is respectively connected with the adjustable stirring paddle clamping head (103) and the power switch (801) in a circuit way.
Preferably, the feeding assembly comprises a timed dosing peristaltic pump (301) provided with a peristaltic pump control panel (302) and a connecting hose (303); one end of the connecting hose (303) is connected with the timing quantitative feeding peristaltic pump (301), and the other end of the connecting hose is connected with a feeding port (702) of the reaction kettle (701); the peristaltic pump control panel (302) is respectively connected with the timing quantitative feeding peristaltic pump (301) and the power switch (801) in a circuit manner.
Preferably, the ultrasonic assembly comprises a vibrator (502) and an ultrasonic control panel (501); the ultrasonic control panel (501) is respectively connected with the vibrator (502) and the power switch (801) in a circuit manner; the vibrator (502) is assembled on the inner wall of the third side plate (404); the ultrasonic control panel (501) is assembled on the outer wall of the second side plate (403).
Preferably, the integrated device for magnetic bead production provided by the utility model further comprises a fixed box body surrounded by a fifth side plate (203), a sixth side plate, a seventh side plate (206), an eighth side plate (205), a second bottom plate (204) and a top plate (201); the reactor main tank is placed in the fixed tank.
Preferably, the top plate (201) includes a first plate body (2011) and a second plate body (2012); one side of the first plate body (2011) and one side of the second plate body (2012) are respectively provided with grooves (2013) with the same positions and shapes.
Preferably, the first plate body (2011) and the second plate body (2012) are slidably arranged at the top of the fixed box body.
Preferably, a water valve (405) is arranged near the bottom of the first side plate (401).
Preferably, the power switch (801) is mounted on an outer wall of the seventh side plate (206).
Preferably, the bottoms of the first bottom plate (402) and the second bottom plate (204) are both provided with universal wheels (901).
Preferably, both ends of the first plate body (2011) and the second plate body (2012) are provided with fixed catches (202); and locking grooves matched with the fixed lock catches (202) are formed near the tops of the fifth side plate (203) and the seventh side plate (206).
Preferably, a through hole (2014) is further formed in the second plate body (2012); the connecting hose (303) penetrates through the through hole (2014).
The integrated device for magnetic bead production provided by the utility model integrates the functions of ultrasonic, stirring, sample adding, temperature control and the like, can simultaneously realize multiple functions in the magnetic bead production process, is simple and convenient to operate, ensures the stability of magnetic beads among batches, realizes the efficient, batch and automatic stable production of magnetic beads, and meets the requirements of the current market on high yield and high quality of nano magnetic beads.
Drawings
FIG. 1 is a schematic cross-sectional view of an integrated apparatus for magnetic bead production according to the present utility model;
FIG. 2 is a schematic cross-sectional structure of the reaction vessel provided by the utility model after being assembled into a main reactor tank;
fig. 3 is a top view of a top plate according to the present utility model.
A stirring control panel 101; a stirring paddle 102; an adjustable paddle clamp 103; a top plate 201; a fixed latch 202; a fifth side plate 203; second floor 204; an eighth side plate 205; a seventh side plate 206; a timed dosing peristaltic pump 301; peristaltic pump control panel 302; a connection hose 303; a first side plate 401; a first base plate 402; a second side plate 403; a third side plate 404; a water valve 405; an ultrasonic control panel 501; a vibrator 502; a temperature control panel 601; a temperature sensor 602; a unit 603; a reaction vessel 701; a feed inlet 702; a power switch 801; a universal wheel 901; a base 902.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments of the present utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
As shown in fig. 1 to 3, the integrated device for magnetic bead production provided in this embodiment includes a main reactor tank, a reaction kettle 701 provided with a feed inlet 702 and assembled on the main reactor tank, a stirring assembly, an ultrasonic assembly, a temperature control assembly, a feed assembly and a power switch 801; the stirring assembly is assembled above the reaction kettle 701; the feeding component is connected with the reaction kettle 701; the ultrasonic assembly, the temperature control assembly, the stirring assembly and the feeding assembly are all in circuit connection with the power switch 801. It can be appreciated by those skilled in the art that the integrated device for magnetic bead production provided by the embodiment integrates functions of ultrasound, stirring, sample adding, temperature control and the like, can simultaneously realize multiple functions in the magnetic bead production process, is simple and convenient to operate, ensures the stability of magnetic beads among batches, and therefore realizes efficient, batch and automatic stable production of magnetic beads, and meets the requirements of the current market on high yield and high quality of nano magnetic beads. Those skilled in the art will appreciate that the reaction vessel 701 is well known in the art and will not be described in detail herein.
Further, the main reactor tank is surrounded by a first side plate 401, a second side plate 403, a third side plate 404, a fourth side plate and a first bottom plate 402 to form a tank structure with one open surface; a base 902 is fixed on top of the first base plate 402; the reaction kettle 701 is fixed on the top of the base 902; the temperature control component comprises a compressor unit 603, a temperature sensor 602 and a temperature control panel 601 of the refrigerator; the temperature control panel 601 is assembled on the outer wall of the second side plate 403; the temperature sensor 602 is mounted on the inner wall of the fourth side plate; the unit 603 is disposed on an inner wall of the first side plate 401; the temperature control panel 601 is respectively connected with the unit 603, the temperature sensor 602 and the power switch 801 in a circuit manner. It can be appreciated by those skilled in the art that pure water can be added into the main tank cavity of the reactor, and the temperature of the unit 603 is controlled by the temperature control panel 601, so that the water temperature required by the reaction kettle 701 is controlled, and the problem of unstable production caused by overhigh temperature in the reaction process is solved.
Further, the stirring assembly comprises a stirring paddle 102, an adjustable stirring paddle chuck 103 and a stirring control panel 101; the top of the stirring paddle 102 is in transmission connection with the adjustable stirring paddle chuck 103, and the other end of the stirring paddle is arranged in the reaction kettle 701; the adjustable stirring paddle clamping head 103 is arranged above the reaction kettle 701; the stirring control panel 101 is respectively connected with the adjustable stirring paddle clamping head 103 and the power switch 801 in a circuit way. Those skilled in the art will appreciate that the desired agitation rate of the reactor 701 may be controlled by parameter setting of the agitation control panel 101. The stirring paddle 102 is made of polytetrafluoroethylene materials. The adjustable paddle clip 103 is prior art in the art and is not described in detail herein.
Further, the feeding assembly comprises a timed dosing peristaltic pump 301 provided with a peristaltic pump control panel 302 and a connecting hose 303; one end of the connecting hose 303 is connected with the timing and quantitative feeding peristaltic pump 301, and the other end is connected with a feeding port 702 of the reaction kettle 701; the peristaltic pump control panel 302 is respectively connected with the timing quantitative feeding peristaltic pump 301 and the power switch 801 in a circuit manner. Those skilled in the art will appreciate that the peristaltic pump control panel 302 can be set to time and quantitatively feed the peristaltic pump 301 parameters, so as to solve the instability factor of artificial sample feeding, liberate labor force and save labor cost. Meanwhile, a peristaltic pump with timing and quantitative can be placed, and space is saved. Those skilled in the art will appreciate that the timing and dosing peristaltic pump 301 is not described in detail herein for the prior art.
Further, the ultrasonic assembly includes a vibrator 502 and an ultrasonic control panel 501; the ultrasonic control panel 501 is respectively connected with the vibrator 502 and the power switch 801 in a circuit manner; the vibrator 502 is assembled on the inner wall of the third side plate 404; the ultrasonic control panel 501 is mounted on the outer wall of the second side plate 403. Those skilled in the art will appreciate that the ultrasound assembly is well known in the art and will not be described in detail herein. Setting ultrasonic parameters and starting an ultrasonic assembly. The vibrator is a prior art in the field and is not described in detail herein.
Further, the integrated apparatus for magnetic bead production provided in this embodiment further includes a fixed box enclosed by a fifth side plate 203, a sixth side plate (not shown), a seventh side plate 206, an eighth side plate 205, a second bottom plate 204, and a top plate 201; the reactor main tank is placed in the fixed tank. It will be appreciated by those skilled in the art that placing the reactor main tank in a fixed tank can provide a thermal insulation effect to the reactor main tank and isolate noise problems generated by the reaction vessel 701.
Further, the top plate 201 includes a first plate body 2011 and a second plate body 2012; one side of the first plate 2011 and one side of the second plate 2012 are provided with grooves 2013 with the same positions and shapes. It can be appreciated by those skilled in the art that when the first plate 2011 and the second plate 2012 are covered, the stirring shaft hole or the feeding hole is reserved through the groove, so that the use of the integrated device for magnetic bead production provided in this embodiment is not affected.
Further, the first plate 2011 and the second plate 2012 are slidably disposed on top of the fixed housing. As will be appreciated by those skilled in the art, the first plate 2011 and the second plate 2012 can be slidably disposed on top of the fixed housing, so that the main housing of the reactor can be easily disassembled.
Further, a water valve 405 is mounted near the bottom of the first side plate 401. Those skilled in the art will appreciate that the pure water in the main tank of the reactor can be conveniently discharged, and the pure water can be conveniently replaced.
Further, the power switch 801 is mounted on the outer wall of the seventh side plate 206.
Further, the bottoms of the first base plate 402 and the second base plate 204 are each equipped with a universal wheel 901. It will be appreciated by those skilled in the art that the universal wheels 901 facilitate movement of the reactor main and stationary tanks.
Further, both ends of the first plate 2011 and the second plate 2012 are provided with fixing catches 202; locking grooves (not shown) matched with the fixed lock 202 are arranged near the tops of the fifth side plate 203 and the seventh side plate 206. As will be appreciated by those skilled in the art, after the first plate 2011 and the second plate 2012 are covered, the top plate 201 is locked to the fifth side plate 203 and the seventh side plate 206 by the fixing buckle 202. The fixing latch 202 is well known in the art and will not be described in detail herein.
Further, a through hole 2014 is further formed in the second plate 2012; the connection hose 303 is inserted through the through hole 2014.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and are not limiting; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present utility model.
Claims (10)
1. An integrated device for magnetic bead production is characterized by comprising a reactor main box, a reaction kettle (701) which is assembled on the reactor main box and provided with a feed inlet (702), a stirring assembly, an ultrasonic assembly, a temperature control assembly, a feed assembly and a power switch (801); the stirring assembly is assembled above the reaction kettle (701); the feeding component is connected with the reaction kettle (701); the ultrasonic assembly, the temperature control assembly, the stirring assembly and the feeding assembly are all in circuit connection with the power switch (801).
2. The integrated device for magnetic bead production according to claim 1, wherein the reactor main tank is surrounded by a first side plate (401), a second side plate (403), a third side plate (404), a fourth side plate and a first bottom plate (402) to form an open-sided tank structure; -a base (902) is secured to the top of the first base plate (402); the reaction kettle (701) is fixed at the top of the base (902); the temperature control assembly comprises a compressor unit (603), a temperature sensor (602) and a temperature control panel (601); the temperature control panel (601) is assembled on the outer wall of the second side plate (403); the temperature sensor (602) is assembled on the inner wall of the fourth side plate; the unit (603) is arranged on the inner wall of the first side plate (401); the temperature control panel (601) is respectively connected with the unit (603), the temperature sensor (602) and the power switch (801) in a circuit mode.
3. The integrated device for magnetic bead production of claim 2, wherein the stirring assembly comprises a stirring paddle (102), an adjustable stirring paddle clamp (103), and a stirring control panel (101); the top of the stirring paddle (102) is in transmission connection with the adjustable stirring paddle chuck (103), and the other end of the stirring paddle is arranged in the reaction kettle (701); the adjustable stirring paddle chuck (103) is arranged above the reaction kettle (701); the stirring control panel (101) is respectively connected with the adjustable stirring paddle clamping head (103) and the power switch (801) in a circuit way.
4. An integrated device for the production of magnetic beads according to claim 3, characterized in that the feeding assembly comprises a timed dosing peristaltic pump (301) provided with a peristaltic pump control panel (302) and a connection hose (303); one end of the connecting hose (303) is connected with the timing quantitative feeding peristaltic pump (301), and the other end of the connecting hose is connected with a feeding port (702) of the reaction kettle (701); the peristaltic pump control panel (302) is respectively connected with the timing quantitative feeding peristaltic pump (301) and the power switch (801) in a circuit manner.
5. The integrated device for magnetic bead production according to claim 4, wherein the ultrasound assembly comprises a vibrator (502) and an ultrasound control panel (501); the ultrasonic control panel (501) is respectively connected with the vibrator (502) and the power switch (801) in a circuit manner; the vibrator (502) is assembled on the inner wall of the third side plate (404); the ultrasonic control panel (501) is assembled on the outer wall of the second side plate (403).
6. The integrated apparatus for magnetic bead production according to claim 5, further comprising a fixed case surrounded by the fifth side plate (203), the sixth side plate, the seventh side plate (206), the eighth side plate (205), the second bottom plate (204), and the top plate (201); the reactor main tank is placed in the fixed tank.
7. The integrated device for magnetic bead production according to claim 6, wherein the top plate (201) comprises a first plate body (2011) and a second plate body (2012); one side of the first plate body (2011) and one side of the second plate body (2012) are respectively provided with grooves (2013) with the same positions and shapes.
8. An integrated device for the production of magnetic beads according to claim 7, characterized in that a water valve (405) is fitted near the bottom of the first side plate (401);
the power switch (801) is assembled on the outer wall of the seventh side plate (206).
9. An integrated device for the production of magnetic beads according to claim 8, characterized in that the bottoms of the first base plate (402) and the second base plate (204) are each equipped with a universal wheel (901).
10. The integrated device for magnetic bead production according to claim 9, wherein the first plate (2011) and the second plate (2012) are slidingly arranged on top of the fixed box; both ends of the first plate body (2011) and the second plate body (2012) are provided with fixed lock catches (202); locking grooves matched with the fixed lock catches (202) are formed near the tops of the fifth side plate (203) and the seventh side plate (206);
a through hole (2014) is further formed in the second plate body (2012); the connecting hose (303) penetrates through the through hole (2014).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321443468.9U CN220405589U (en) | 2023-06-07 | 2023-06-07 | Integrated device for magnetic bead production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321443468.9U CN220405589U (en) | 2023-06-07 | 2023-06-07 | Integrated device for magnetic bead production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220405589U true CN220405589U (en) | 2024-01-30 |
Family
ID=89640665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321443468.9U Active CN220405589U (en) | 2023-06-07 | 2023-06-07 | Integrated device for magnetic bead production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220405589U (en) |
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2023
- 2023-06-07 CN CN202321443468.9U patent/CN220405589U/en active Active
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