CN220327544U - Tracheal intubation device for rats and mice - Google Patents

Abstract

The application relates to the field of experimental equipment, in particular to a rat tracheal intubation device. The device comprises an operation table, an inclined plate detachably connected with the operation table and a light source device arranged on the operation table; the operation table comprises a base and a positioning plate which are movably connected; the positioning plate is provided with a soft cushion, the soft cushion is provided with a head and neck fixing assembly and a trunk fixing assembly, one surface of the positioning plate opposite to the soft cushion is provided with a plurality of protruding inserting blocks, and slots of the inclined plate are formed between every two adjacent inserting blocks; the soft cushion is provided with an incisor fixing piece and a lingual clamp; one end of the inclined plate is connected with the base, and the other end of the inclined plate is arranged at the slot. The application has the advantages of reducing complications such as long-time operation warming, limb ischemia, pressure sore and the like of animals; better exposing the animal glottic structures; fixing the body positions of mice with different sizes; a movable adjustment; easy storage and the like.

Description

Tracheal intubation device for rats and mice

Technical Field

The application relates to the field of experimental equipment, in particular to a rat and mouse trachea cannula device.

Background

The 1999 Brown et al (Brown RH, walters DM, greenberg RS, et al A method of endotracheal intubation and pulmonary functional assessment for repeated studies in mice [ J ]. J Appl Physiol,1999, 87:2362-2365) published a method for tracheal intubation of mice, which is widely used in the fields of airway administration, pulmonary function determination, viral infection, and lung injury modeling. In the establishment of a plurality of models, the mice need to be repeatedly subjected to tracheal intubation for a plurality of times, so that the risk of injury to the trachea of the mice is increased. There is therefore a need for a simple portable, single person operable, non-invasive endotracheal intubation console for rats.

The existing mouse intubation bed has the following defects: the surface is not covered with the soft cushion, which is easy to cause limb ischemia of the big and small animals; the heat preservation of the big mouse and the small mouse cannot be carried out; the brightness of the cold light source is not adjustable, and the requirements of animals with different sizes under different conditions cannot be met; the animal can not reach the required body position of the intubation when intubating; the body position stability of the big mouse and the small mouse is poor; the surface of the cannula bed is easy to pollute; is not easy to be stored. Therefore, the design is needed to reduce complications such as long-time operation hypothermia, limb ischemia, pressure sore and the like of animals; better exposing the animal glottic structures; fixing the body positions of mice with different sizes; a movable adjustment; easy to store; the success rate of trachea cannula is higher, and big mouse trachea cannula bed that single can operate.

Disclosure of Invention

In view of the above drawbacks of the prior art, an object of the present application is to provide a rat tracheal intubation device for solving the problems in the prior art.

To achieve the above and other related objects, according to one aspect of the present utility model, there is provided a rat tracheal intubation device, comprising an operation table, a sloping plate detachably connected to the operation table, and a light source device disposed on the operation table; the operation table comprises a base and a positioning plate which are movably connected; the positioning plate is provided with a soft cushion, the soft cushion is provided with a head and neck fixing assembly and a trunk fixing assembly, one surface of the positioning plate opposite to the soft cushion is provided with a plurality of protruding inserting blocks, and slots of the inclined plate are formed between every two adjacent inserting blocks; the soft cushion is provided with an incisor fixing piece and a lingual clamp; one end of the inclined plate is connected with the base, and the other end of the inclined plate is arranged in the slot.

In any embodiment of the present application, the head and neck fixation assembly comprises a neck pad having a neck collar thereon, the neck pad and neck collar being connected by a neck collar fixation.

In any embodiment of the present application, the torso fixing assembly includes a torso clamp and a torso guide post connected.

In any embodiment of the application, the positioning plate is provided with one or more sliding rails, the head and neck fixing component is provided with head adjusting sliding blocks corresponding to the sliding rails one by one, the trunk fixing component is provided with trunk adjusting sliding blocks corresponding to the sliding rails one by one, and the head adjusting sliding blocks and the trunk adjusting sliding blocks can slide along the sliding rails respectively; the neck pad is connected with each head adjusting slide block through a head guide post respectively, and the trunk clamp is connected with each trunk adjusting slide block through a trunk guide post respectively.

In any embodiment of the present application, the trunk adjusting slider is provided with a first adjuster for adjusting the height of the trunk guide post relative to the cushion.

In any embodiment of the present application, the trunk adjusting slide block is further provided with a first fixing member, which is used for fixing the position of the trunk adjusting slide block on the slide rail.

In any embodiment of the present application, the head adjusting slider is provided with a second adjuster for adjusting the height of the head guide post relative to the cushion.

In any embodiment of the present application, the head adjusting slider is further provided with a second fixing member, which is used for fixing the position of the head adjusting slider on the sliding rail.

In any embodiment of the present application, each of the head adjustment sliders is symmetrically disposed with respect to the neck ring.

In any embodiment of the present application, each of the torso adjustment sliders is symmetrically disposed with respect to the neck ring.

In any embodiment of the present application, the cushion is detachably connected to the positioning plate, and in the connection state, a gap is left between the cushion and the edge of the positioning plate.

In any embodiment of the present application, the light source device includes a fixing button, a lamp arm, and a light source head connected in sequence.

In any embodiment of the present application, the base is provided with a cold light source brightness cold light source adjusting knob for controlling the light source head, a heating knob for adjusting the temperature of the soft cushion, and a thermometer for displaying the temperature of the soft cushion.

In any embodiment of the present application, the light arm is a plastic hose.

In any embodiment of the present application, the base is provided with a hollow structure for accommodating the positioning plate.

Compared with the prior art, the beneficial effects of this application are:

1. the inclination angle of the operation table is changed by adjusting the insertion blocks of the saw-tooth structure on the lower side surface of the positioning plate, so that the operation table is simple, convenient and high in stability.

2. When the lamp is used, the cold light source lamp arm is adjusted to enable light to directly penetrate through the front neck region, so that glottis exposure is clearer, the failure rate of intubation is reduced, the brightness of the glottis is adjusted through the light source adjusting knob after the light position is fixed, and the requirements of mice with different body types are met.

3. The movable neck pad can better enable the heads of the rats and the mice to lean backwards, and the glottic exposure degree is increased.

4. The sliding rail design can better increase the stability of the trunk clamp and the neck pad, and can also increase the possibility of accessories for meeting different operation demands.

5. During specific experiments, the surface of the soft cushion can be wrapped with sterile cloth and replaced regularly, so that the possibility of infection of rats and mice in the experiments is reduced.

6. The junction of the locating plate and the base adopts a knob design, and the locating plate can be stored after the experiment is finished.

7. The trunk clamp and the neck ring are added, so that the stability of the mice is improved, and the risks of trachea cannula slipping and trachea injury caused by body position change in the intubation process and after intubation are prevented.

Drawings

Fig. 1 shows a side view of the present application.

Fig. 2 shows an operational face view of the present application.

Figure 3 is a detailed view of the torso retaining assembly of the present application.

Fig. 4 is a detail view of the head and neck fixation assembly of the present application.

Description of element numbers:

1. operating table

11. Cushion for soft mattress

111. Incisor fixing piece

112. Tongue clip

12. Plug-in block

13. Base seat

131. Cold light source adjusting knob

132. Heating knob

133. Thermometer with a temperature sensor

14. Positioning plate

141. Sliding rail

2. Head and neck fixing assembly

21. Neck pad

22. Neck ring

23. Neck ring fixing part

24. Head guide post

25. Head adjusting slide block

251. Second regulator

252. Second fixing piece

3. Torso fixing assembly

31. Trunk clamp

32. Trunk guide post

33. Trunk adjusting slide block

331. First regulator

332. First fixing piece

4. Light source device

41. Fixing button

42. Lamp arm

43. Light source

5. Sloping plate

Detailed Description

The following detailed description of the embodiments of the present application is provided in further detail with reference to the accompanying drawings. These embodiments are merely illustrative of the present application and are not limiting of the present application.

The terms "center," "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used for convenience in describing and simplifying the description based on the orientation or positional relationship shown in the drawings, and do not denote or imply that the devices or elements referred to must have a particular orientation, be configured and operated in a particular orientation, and thus should not be construed as limiting the present application. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present application, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the terms in this application will be understood by those of ordinary skill in the art as the case may be.

Furthermore, in the description of the present application, unless otherwise indicated, the meaning of "a plurality" is two or more.

As shown in fig. 1, the present application provides a rat tracheal intubation device, which comprises an operation table, a sloping plate 5 detachably connected with the operation table 1, and a light source device 4 arranged on the operation table 1. The operating platform 1 comprises a base 13 and a positioning plate 14 which are movably connected. In some embodiments, the base 13 and the positioning plate 14 may be hingedly connected.

The positioning plate 14 is provided with a soft cushion 11, the soft cushion 11 is provided with a head and neck fixing assembly 2 and a trunk fixing assembly 3, one surface of the positioning plate 14 opposite to the soft cushion 11 is provided with a plurality of protruding inserting blocks 12, and a slot 15 of the inclined plate 5 is formed between every two adjacent inserting blocks 12. One end of the sloping plate 5 is connected with the base 13, and the other end is arranged in the slot 15. In a preferred embodiment of the present application, when the lower edge of the swash plate 5 abuts against the highest insert 12, a baffle is disposed on the positioning plate 14 near the highest insert 12 for fixing the position of the swash plate 5. The swash plate 5 of the present application may be interposed between different inserts 12 as required for the experiment. In a specific embodiment of the present application, the plurality of insert blocks 12 form a saw-tooth structure, and by adjusting the position of the inclined plate 5, the inclination angle of the console 1 can be changed, so that the device of the present application is simple and convenient and has high stability.

As shown in fig. 1 and 2, the cushion 11 is provided with an incisor holder 111 and a tongue clip 112. In a preferred embodiment of the present application, the incisor fasteners 111 and lingual clips 112 are disposed adjacent the head and neck fixation assembly 2. In a specific embodiment of the present application, the incisor fasteners 111 may be hooks, for example, zigzag hooks, by suspending upper row incisors of the mice by zigzag hooks, and moving the hook positions according to the body shape and desired positions of the mice.

As shown in fig. 2, in the tracheal intubation device for a rat and a mouse provided by the application, the head and neck fixing component 2 comprises a neck pad 21, a neck ring 22 is arranged on the neck pad 21, and the neck pad 21 and the neck ring 22 are connected through a neck ring fixing piece 23. In one embodiment of the present application, the end of the collar 22 and the collar securing member 23 may be, for example, gear structures, so that the collar 22 can be conveniently adjusted to the length of the neck of the mouse according to the body shape of the mouse, and the collar is fixed by the engagement between the gears.

As shown in fig. 3, in the tracheal intubation device for a rat and a mouse provided in the present application, the trunk fixing assembly 3 includes a trunk clamp 31 and a trunk guide post 32 which are connected. In this application embodiment, accessible sticky tape mode such as fixed big mouse four limbs during the experiment, on this basis trunk body anchor clamps 31 press from both sides and locate the armpit of mouse, and the inboard reason body of trunk body anchor clamps 31 is watery to paste big mouse truck, is convenient for fix the center truck of mouse, has increased the stability of big mouse, prevents in intubate in-process and intubate back position change and the risk of trachea intubate slippage and damage trachea that leads to.

As shown in fig. 2 to 4, in the tracheal intubation device for mice provided by the present application, one or more sliding rails 141 are provided on the positioning plate 14, head adjusting sliders 25 corresponding to the sliding rails 141 one to one are provided on the head and neck fixing assembly 2, torso adjusting sliders 33 corresponding to the sliding rails 141 one to one are provided on the torso fixing assembly 3, and the head adjusting sliders 25 and the torso adjusting sliders 33 can slide along the sliding rails 141 respectively. The slide rail design of this application can adjust the position of trunk anchor clamps 31 and neck pad 31 better, also realizes increasing the possibility of accessory for satisfying different operation demands to improve holistic stability. The sliding of the head adjusting sliding block 25 relative to the sliding rail 141 is controlled, so that the neck pad 21 can move on the soft cushion 11, and the neck of a rat and a mouse can be well bent back, so that the glottis can be better exposed. It should be well known to those skilled in the art that the slide rail may also be hinged, gear, electromagnetically, etc. to effect movement and fixation of the head and neck fixation assembly 2 and torso fixation assembly 3.

As shown in fig. 3 to 4, in the tracheal intubation device for a rat and a mouse provided in the present application, a trunk clamp 31 and each trunk adjusting slider 33 are respectively connected through a trunk guide post 32. The trunk adjusting slide 33 is provided with a first adjuster 331 for adjusting the height of the trunk guiding pillar 32 relative to the cushion 11. The body adjusting slider 33 is further provided with a first fixing member 332 for fixing the position of the body adjusting slider 33 on the slide rail 141. In one embodiment of the present application, the side of the trunk adjusting slider 33 near the sliding rail 141 is provided with a groove, so as to move along the sliding rail 141 and be fixed by the first fixing member 332.

As shown in fig. 4, in the tracheal intubation device for a rat and a mouse provided in the present application, the cervical pad 21 and each head adjusting slider 25 are respectively connected through the head guide post 24. The head adjusting slider 25 is provided with a second adjuster 251 for adjusting the height of the head guide post 24 relative to the cushion 11. The head adjusting slide 25 is further provided with a second fixing piece 252 for fixing the position of the head adjusting slide 25 on the slide rail 141.

In some embodiments, the first adjuster 331 or the second adjuster 251 is provided with a cavity for accommodating the trunk guide post 32 or the head guide post 24, so that the trunk guide post 32 or the head guide post 24 slides therein, and is adjusted to a proper position according to experimental requirements, and is fixed respectively, for example, by a combination of a screw and a bolt when fixed.

It should be well known to those skilled in the art that the first fixing member 332 or the second fixing member 252 may be, for example, a screw fastener such as a combination of a screw and a bolt, a beam fixing member, or a fitting suitable for fixing such as a metal plate and a panel fastener.

As shown in fig. 2, in the tracheal intubation device for mice provided in the present application, each head adjusting slider 25 is symmetrically distributed with respect to the neck ring 22, and each trunk adjusting slider 33 is symmetrically distributed with respect to the neck ring 22. In one embodiment of the present application, during use, the height of the head adjusting sliders 25 on both sides of the console 1 is consistent with respect to the base 13, so that the mouse can better finish neck recline and better expose glottis. The trunk adjusting sliding blocks 33 on the two sides of the operation table 1 are consistent in height relative to the base 13, so that the trunk of a rat can be fixed better.

As shown in fig. 1, in the tracheal intubation device for a rat and a mouse provided in the present application, the cushion 11 is detachably connected with the positioning plate 14. In the connected state, a gap is left between the cushion 11 and the edge of the positioning plate 14. In a specific embodiment of the present application, the central position of the cushion 11 and the positioning plate 14 is adhered by the magic tape, so that a gap is left between the cushion 11 and the edge of the positioning plate 14, and during specific experiments, the surface of the cushion 11 can be wrapped with sterile cloth, and the sterile cloth is plugged into the gap for fixation, so that the sterile cloth is not easy to shift. The sterile cloth can be replaced every time of experiments, so that the possibility of infection of mice and rats in the experiments is reduced.

As shown in fig. 1, in the tracheal intubation device for a rat and a mouse provided in the present application, the light source device 4 includes a fixing button 41, a light arm 42 and a light source head 43 which are sequentially connected. The base 13 is provided with a cold light source adjusting knob 131 for controlling the brightness of the cold light source of the light source 43, a warming knob 132 for adjusting the temperature of the cushion 11, and a thermometer 133 for displaying the temperature of the cushion 11. In a specific embodiment of the present application, the tunable cold light source may be implemented by a capacitor series type, a diode series type, a resistor series type, an autotransformer type, a thyristor type, a transistor type, or the like. The heatable cushion 11 can adopt heating modes such as heat conduction wire heating, circulating water heating and the like to realize the heat preservation of the mice, prevent the occurrence of hypothermia in the operation of the mice and reduce complications such as postoperative shivering of the mice.

In some embodiments, the base 13 and the positioning plate 14 may be hinged, and the fixing between the positioning plate 14 and the base 13 is achieved by the fixing button 41. The lamp arm 42 is a plastic hose, for example, a plastic hose can be used, and plastic materials such as silica gel can be used, so that the lamp arm can be bent and deformed in the use process and can be fixed after being bent and deformed, the plastic hose material used in the lamp arm is adopted by those skilled in the art conventionally, and the plastic hose for the lamp arm can ensure the stability of lamplight in the intubation process. In use, the lamp arm 42 is adjusted to enable light to directly penetrate through the anterior cervical region, so that glottis exposure is clearer, and the failure rate of intubation is reduced. After the position of the light source 43 is fixed, the glottal brightness is adjusted through the cold light source adjusting knob 131, so that different experimental requirements are met.

As shown in fig. 1, in the tracheal intubation device for mice provided in the present application, a hollow structure for accommodating the positioning plate 14 is provided on the base 13. In a specific embodiment of the present application, when the device is used, the sloping plate 5 can be detached, and the fixing button 41 can be unscrewed, so that the positioning plate 14 falls into the base 13, and the device is in a box-packed structure, so that the device is convenient to store.

The big mouse trachea cannula device that this application provided can satisfy: reducing complications such as long-time operation warming, limb ischemia, pressure sore and the like of animals; better exposing the animal glottic structures; fixing the body positions of mice with different sizes; a movable adjustment; easy to store; the trachea cannula has higher success rate, single person operability and other conditions, and has good application scene on the trachea cannula of the rats and the mice.

The application process of the rat trachea cannula device comprises the following steps:

after anesthesia, the upper incisors of the rats are hooked by the zigzag hooks on the incisor holders 111 by placing the rats on the cushion 11. The limbs of the mice were fixed to the cushion 11 by tape bonding. The neck pad 21 is placed under the neck of the big mouse by adjusting the head guide post 24, so that the neck of the big mouse is in an overstretched position, the tongue of the big mouse is clamped by the tongue clamp 112 and pulled to one side of the oral cavity, and the tongue is ensured not to influence the observation of the glottic structure by an experimenter. The collar 22 was adjusted so that the collar 22 could fix the cervical position of the rat and not affect the patency of the rat airway. The trunk guide post 32 and the first adjuster 331 are adjusted so that the upper edge of the trunk clamp 31 can be just placed under the armpits of the big and small mice, and the inner edge of the trunk clamp 31 is placed at the waist of the big and small mice, so that the stability of the trunk parts of the big and small mice is ensured. The cold light source lamp arm 42 which can be shaped is adjusted so that the light of the cold light source can just pass through the skin of the cervical region of the rat and the skin of the mouse, and the brightness of the cold light source is adjusted through the cold light source adjusting knob 131, so that the definition of a glottic structure is ensured. The opening and closing movement of the glottis of the large and small mice can be clearly observed through the oral cavity of the large and small mice, the handheld tracheal catheter is inserted into the glottis when the glottis are opened, the tracheal catheter is fixed at a proper depth and connected with a breathing machine, and the breathing movement of the large and small mice is observed through methods such as double-lung auscultation to judge whether the intubation is successful or not. The temperature of the heat preservation pad is adjusted by the heating knob 132 when necessary to prevent the mice from losing temperature.

In conclusion, the application has the advantages of reducing complications such as long-time operation hypothermia, limb ischemia, pressure sore and the like of animals; better exposing the animal glottic structures; fixing the body positions of mice with different sizes; a movable adjustment; easy storage and the like.

In conclusion, the method and the device effectively overcome various defects in the prior art and have high industrial utilization value.

The foregoing embodiments are merely illustrative of the principles of the present application and their effectiveness, and are not intended to limit the application. Modifications and variations may be made to the above-described embodiments by those of ordinary skill in the art without departing from the spirit and scope of the present application. Accordingly, it is intended that all equivalent modifications and variations which may be accomplished by persons skilled in the art without departing from the spirit and technical spirit of the disclosure be covered by the claims of this application.

Claims (10)

1. The rat trachea cannula device is characterized by comprising an operation table (1), a sloping plate (5) detachably connected with the operation table (1), and a light source device (4) arranged on the operation table (1); the operation table (1) comprises a base (13) and a positioning plate (14) which are movably connected; the positioning plate (14) is provided with a soft cushion (11), the soft cushion (11) is provided with a head and neck fixing assembly (2) and a trunk fixing assembly (3), one surface of the positioning plate (14) opposite to the soft cushion (11) is provided with a plurality of protruding inserting blocks (12), a slot (15) of the inclined plate (5) is formed between every two adjacent inserting blocks (12), one end of the inclined plate (5) is connected with the base (13), and the other end of the inclined plate (5) is arranged in the slot (15); the soft cushion (11) is provided with an incisor fixing piece (111) and a lingual clamp (112).

2. The rat tracheal intubation device of claim 1, wherein the head and neck fixation assembly (2) comprises a neck pad (21), the neck pad (21) having a neck collar (22), the neck pad (21) and neck collar (22) being connected by a neck collar fixation (23);

and/or, the trunk fixing assembly (3) comprises a trunk clamp (31) and a trunk guide post (32) which are connected.

3. The tracheal intubation device of the rat and mouse according to claim 2, wherein the positioning plate (14) is provided with one or more sliding rails (141), the head and neck fixing assembly (2) is provided with head adjusting sliding blocks (25) which are in one-to-one correspondence with the sliding rails (141), the trunk fixing assembly (3) is provided with trunk adjusting sliding blocks (33) which are in one-to-one correspondence with the sliding rails (141), and the head adjusting sliding blocks (25) and the trunk adjusting sliding blocks (33) can respectively slide along the sliding rails (141); the neck pad (21) is connected with each head adjusting slide block (25) through a head guide post (24), and the trunk clamp (31) is connected with each trunk adjusting slide block (33) through a trunk guide post (32).

4. A rat tracheal intubation device according to claim 3, characterized in that said trunk adjusting slide (33) is provided with a first adjuster (331) for adjusting the height of said trunk guiding post (32) with respect to said cushion (11);

and/or, the trunk adjusting slide block (33) is further provided with a first fixing piece (332) for fixing the position of the trunk adjusting slide block (33) on the sliding rail (141).

5. A rat tracheal intubation device according to claim 3, characterized in that said head adjustment slider (25) is provided with a second adjuster (251) for adjusting the height of said head guide post (24) with respect to said cushion (11);

and/or, the head adjusting slide block (25) is also provided with a second fixing piece (252) for fixing the position of the head adjusting slide block (25) on the slide rail (141).

6. A rat tracheal intubation device according to claim 3, characterized in that each of said head-adjusting slides (25) is symmetrically distributed with respect to said collar (22);

and/or, each of said torso adjustment sliders (33) is symmetrically distributed with respect to said neck ring (22).

7. A rat tracheal intubation device as in claim 1, wherein said cushion (11) is detachably connected to said positioning plate (14); in the connection state, a gap is reserved between the soft cushion (11) and the edge of the positioning plate (14).

8. A rat tracheal intubation device according to claim 1, characterized in that the light source device (4) comprises a fixed button (41), a lamp arm (42) and a light source head (43) connected in sequence.

9. A rat tracheal intubation device according to claim 8, wherein the base (13) is provided with a cold light source adjustment knob (131) for controlling the brightness of the cold light source of the light source head (43), a warming knob (132) for adjusting the temperature of the cushion (11), and a thermometer (133) for displaying the temperature of the cushion (11);

and/or the lamp arm (42) is a plastic hose.

10. A rat tracheal intubation device according to claim 1, characterized in that said base (13) is provided with a hollow structure for housing said positioning plate (14).