CN220265707U - Immune cell in-vitro culture device - Google Patents
Immune cell in-vitro culture device Download PDFInfo
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- CN220265707U CN220265707U CN202320603046.7U CN202320603046U CN220265707U CN 220265707 U CN220265707 U CN 220265707U CN 202320603046 U CN202320603046 U CN 202320603046U CN 220265707 U CN220265707 U CN 220265707U
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- immune cell
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- 210000002865 immune cell Anatomy 0.000 title claims abstract description 20
- 238000000338 in vitro Methods 0.000 title claims abstract description 16
- 238000007789 sealing Methods 0.000 claims description 20
- 238000009434 installation Methods 0.000 claims description 12
- 238000003860 storage Methods 0.000 claims description 10
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 9
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 9
- 241001330002 Bambuseae Species 0.000 claims description 9
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 9
- 239000011425 bamboo Substances 0.000 claims description 9
- 239000000463 material Substances 0.000 description 11
- 210000004027 cell Anatomy 0.000 description 9
- 238000012258 culturing Methods 0.000 description 4
- 238000004113 cell culture Methods 0.000 description 3
- 210000004698 lymphocyte Anatomy 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000028993 immune response Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000010146 3D printing Methods 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 239000002801 charged material Substances 0.000 description 1
- 238000003501 co-culture Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 210000004443 dendritic cell Anatomy 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 238000012606 in vitro cell culture Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
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- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses an immune cell in-vitro culture device which comprises a culture device, wherein a plurality of uniformly arranged mounting blocks are arranged on two sides of the inside of the culture device, T-shaped clamping blocks are fixedly arranged on one side of the inside of the mounting blocks, telescopic cylinders are arranged inside the T-shaped clamping blocks, telescopic rods are arranged at two ends of each telescopic cylinder, inserting blocks are fixedly arranged at one ends of each telescopic rod, springs sleeved outside the telescopic rods are arranged between the inserting blocks and the telescopic cylinders, a culture disc is arranged between the two mounting blocks, T-shaped clamping grooves are formed in two sides of the inside of the culture disc, the T-shaped clamping blocks are clamped into the T-shaped clamping grooves, clamping grooves positioned in the culture disc are formed in two ends of the T-shaped clamping grooves, fixed U-shaped stop blocks are clamped into the clamping grooves, and slots are formed in two ends of the inside of the fixed U-shaped stop blocks. The integrated cultivation disk can be conveniently taken and placed, so that the stability of the integrated cultivation disk is improved, and meanwhile, the cultivation efficiency is improved.
Description
Technical Field
The utility model relates to the technical field of immune cell in-vitro culture devices, in particular to an immune cell in-vitro culture device.
Background
Immune cells refer to cells involved in or associated with an immune response. Including lymphocytes, dendritic cells, monocytes macrophages, granulocytes, mast cells, and the like. Immune cells can be divided into a variety of classes, and various immune cells play an important role in humans. Immune cells are commonly known as leukocytes and include congenital lymphocytes, various phagocytes, etc., and lymphocytes that recognize antigens, produce specific immune responses, etc.
The culture of immune cells refers to a method for simulating in-vivo environment (such as sterility, proper temperature, pH value, a certain nutrition condition and the like) in vitro to enable the immune cells to survive, grow, reproduce and maintain main structures and functions, and the cell culture device can be used for in-vitro culture of cell tissues and is widely applied to research and production in the scientific fields of microorganisms, medicine, pharmacy, environmental protection, food, livestock and the like.
Although the field of biological tissue engineering has been developed very rapidly, many materials are subjected to in vitro cell culture by means of 3D printing and other techniques, the processed scaffold material is mainly placed in a culture dish for co-culture, and performance evaluation or differentiation research is performed by "seeding" cells or tissues on the scaffold material. The above method is feasible for most materials that can be directly immersed in a liquid, but has limitations for the use of some already formed film materials, charged materials, materials that cannot be directly contacted with a liquid to be encapsulated, materials that cannot be well fixed at the bottom of a culture dish, etc.
Aiming at the prior patent number CN202011415857.1, the cell in-vitro culture device is disclosed, the cell in-vitro culture device is adopted to have advantages in the research field of applying the membrane material to cell differentiation and compatibility test, the cell culture membrane can realize full material coverage, the problem that the traditional membrane material is fixed on the bottom surface of a culture dish to cause uneven bottom surface or the property of the fixed material interferes with experiments is solved, the prior culture device is divided into a plurality of culture trays for culturing cells, the culture trays are cultured by the small culture trays, the culture trays are placed to drop and damage the cells if shaking, the culture trays are influenced, and the phenomenon is reduced by the existing integrated detachable culture trays; therefore, the existing requirements are not met, and an in vitro immune cell culture device is provided.
Disclosure of Invention
The utility model aims to provide an immune cell in-vitro culture device, which aims to solve the problems that the existing culture device is divided into a plurality of culture trays for culturing when culturing cells, the culture trays are all cultured through small-sized culture trays, the culture trays are placed to shake to cause falling damage and influence the culturing of cells, the existing integrated detachable culture trays are used, the occurrence of the phenomenon is reduced, and the like.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides an immune cell external culture apparatus, includes culture apparatus, the inside both sides of culture apparatus are equipped with a plurality of evenly arranged's installation piece, the inside one side of installation piece is fixed and is equipped with T type fixture block, the inside of T type fixture block is equipped with flexible section of thick bamboo, the both ends of flexible section of thick bamboo all are equipped with the telescopic link, two the one end of telescopic link is all fixed and is equipped with the inserted block, be equipped with the cover between inserted block and the flexible section of thick bamboo and establish the outside spring of telescopic link, two be equipped with the cultivation dish between the installation piece, the inside both sides of cultivation dish all are equipped with T type draw-in groove, T type fixture block card is gone into T type draw-in groove, the both ends of T type draw-in groove all are equipped with fixed U type dog, fixed U type dog card is gone into in the draw-in groove, the slot has all been seted up at the inside both ends of fixed U type dog, two the inserted block all inserts in two slots.
Preferably, the upper end face of the cultivation disk is provided with a plurality of storage tanks, a sealing cover is arranged above the storage tanks, and an auxiliary handle is fixedly arranged on the upper end face of the sealing cover.
Preferably, the four end feet of the storage groove are provided with positioning grooves positioned on the upper end face of the cultivation disk, the four end feet of the sealing cover are fixedly provided with positioning blocks, and the four positioning blocks are clamped into the four positioning grooves.
Preferably, the inside top of culture apparatus is equipped with the temperature regulation lamp, the inside both sides of culture apparatus all are equipped with a plurality of LED lamps, four terminal feet of culture apparatus below all are equipped with the universal wheel, four the universal wheel all is equipped with the locking piece.
Preferably, a console is arranged above the culture device, a control button is arranged on the front end face of the console, a sealing door is arranged on the front end face of the culture device, a handle is arranged on the front end face of the sealing door, an observation window is arranged on the front end face of the sealing door, and a hinge is connected between the sealing door and the culture device.
Compared with the prior art, the utility model has the beneficial effects that:
according to the utility model, when the fixing U-shaped baffle block is taken out through disassembly, the insert blocks in the slots at the two ends of the inner part of the fixing U-shaped baffle block are pulled outwards by the driving of the pulling force, so that the springs with one ends sleeved outside the telescopic rods are compressed, the telescopic rods and the telescopic cylinders stretch out and draw back, the insert blocks are separated from the slots, the fixing U-shaped baffle block is separated from the clamping slots in the cultivating plate, when the cultivating plate is pulled outwards, the T-shaped clamping blocks on one side of the mounting block slide in the T-shaped clamping slots in the two sides of the cultivating plate, the cultivating plate is taken down, the T-shaped clamping blocks are aligned with the T-shaped clamping slots in the two sides of the cultivating plate during installation, then the fixing U-shaped baffle block is clamped into the clamping slots in the cultivating plate for fixing, meanwhile, the bevel edge structures of the fixing U-shaped baffle block are mutually contacted with the bevel edge structures of the insert blocks in the fixing U-shaped baffle block to extrude one ends, and the telescopic rods between the insert blocks and the telescopic cylinders and the springs sleeved outside are in the telescopic adjusting motion, when the inserting slots reach the slots, and the springs are released for elastic and the insert blocks are inserted into the slots for fixing.
Drawings
FIG. 1 is a schematic view of the overall structure of the present utility model;
FIG. 2 is a schematic view of the overall internal structure of the present utility model;
FIG. 3 is a schematic view showing a partial structure of the cultivating plate of the present utility model;
FIG. 4 is a schematic view showing a partial structure of the fixation of the cultivating plate of the present utility model.
In the figure: 1. a culture device; 2. a console; 3. a temperature regulating lamp; 4. an LED lamp; 5. a mounting block; 6. a cultivating tray; 7. a storage tank; 8. sealing cover; 9. a positioning block; 10. a positioning groove; 11. a T-shaped clamping groove; 12. a telescopic cylinder; 13. a telescopic rod; 14. inserting blocks; 15. a spring; 16. a T-shaped clamping block; 17. fixing a U-shaped stop block; 18. a slot; 19. a clamping groove.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments.
Referring to fig. 1 to 4, an embodiment of the present utility model provides: the utility model provides an immune cell external culture device, including culture apparatus 1, culture apparatus 1 inside both sides are equipped with a plurality of evenly arranged's installation piece 5, the inside one side of installation piece 5 is fixed and is equipped with T type fixture block 16, the inside of T type fixture block 16 is equipped with flexible section of thick bamboo 12, the both ends of flexible section of thick bamboo 12 all are equipped with telescopic link 13, the one end of two telescopic links 13 is all fixed and is equipped with the inserted block 14, be equipped with the cover between inserted block 14 and the flexible section of thick bamboo 12 and establish at the outside spring 15 of telescopic link 13, be equipped with between two installation pieces 5 and cultivate dish 6, cultivate the inside both sides of dish 6 all and be equipped with T type draw-in groove 11, T type fixture block 16 card goes into T type draw-in groove 11, the both ends of T type draw-in groove 11 all are equipped with and are located the draw-in groove 19 of cultivating dish 6, the both sides of cultivateing dish 6 all are equipped with fixed U type dog 17, fixed U type dog 17 card goes into draw-in groove 19, slot 18 has all been seted up at the inside both ends of fixed U type dog 17, two inserted block 14 all insert into in two slots 18.
Wherein, a plurality of storage tanks 7 have been seted up to the up end of cultivating dish 6, and the top of storage tank 7 is equipped with sealed lid 8, and the up end of sealed lid 8 is fixed to be equipped with auxiliary handle.
Through adopting above-mentioned technical scheme, when taking out through dismantling, will fix U type dog 17 outside pulling for the inside inserted block 14 of its inside both ends slot 18 is extruded by tensile drive, then makes its one end cover establish at the outside spring 15 of telescopic link 13 compressed.
The four end feet of the storage groove 7 are provided with positioning grooves 10 positioned on the upper end face of the cultivation disk 6, the four end feet of the sealing cover 8 are fixedly provided with positioning blocks 9, and the four positioning blocks 9 are clamped into the four positioning grooves 10; the inside top of culture apparatus 1 is equipped with temperature regulation lamp 3, and the inside both sides of culture apparatus 1 all are equipped with a plurality of LED lamps 4, and four terminal feet of culture apparatus 1 below all are equipped with the universal wheel, and four universal wheels all are equipped with the locking piece.
The top of culture apparatus 1 is equipped with controls platform 2, and the preceding terminal surface of controlling platform 2 is equipped with control button, and culture apparatus 1's preceding terminal surface is equipped with sealing door, and sealing door's preceding terminal surface is equipped with the handle, and sealing door's preceding terminal surface is equipped with the observation window, is connected with the hinge between sealing door and the culture apparatus 1.
In summary, this culture apparatus is when using, when taking out through dismantling, pull the fixed U type dog 17 outside, make its inside inserted block 14 of both ends slot 18 by tensile drive extrusion, then make its one end cover establish at the outside spring 15 of telescopic link 13 compressed, simultaneously telescopic link 13 carries out telescopic motion with telescopic tube 12, make inserted block 14 break away from slot 18, simultaneously fixed U type dog 17 also break away from the inside draw-in groove 19 of cultivation dish 6, in the T type draw-in groove 11 that makes the T type fixture block 16 of installing block 5 one side in cultivation dish 6 both sides are when sliding through pulling cultivation dish 6 outside, will cultivate dish 6 take off can, with T type fixture block 16 aim at the T type draw-in groove 11 slip joint of cultivation dish 6 both sides during the installation, then fix the inside draw-in groove 19 of fixed U type dog 17 card income cultivation dish 6 in, simultaneously the hypotenuse structure of fixed U type dog 17 contacts each other with its inside inserted block 14 and extrudees to one end, simultaneously, the hypotenuse structure between inserted block 14 and telescopic tube 12 and set up spring 13 and set up outside spring 15 and then the inside spring 15 and arrive at the inside slot 18 when adjusting, can be fixed in the time, the flexible slot 18 is reached.
It will be evident to those skilled in the art that the utility model is not limited to the details of the foregoing illustrative embodiments, and that the present utility model may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the utility model being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (5)
1. An immune cell in vitro culture device, comprising a culture device (1), characterized in that: the utility model discloses a cultivation device, including cultivation device (1), including installation piece (5) of cultivation device (1), installation piece (5), inside one side of installation piece (5) is fixed to be equipped with T type fixture block (16), the inside of T type fixture block (16) is equipped with flexible section of thick bamboo (12), the both ends of flexible section of thick bamboo (12) all are equipped with telescopic link (13), two the one end of telescopic link (13) is all fixed to be equipped with inserted block (14), be equipped with the cover between inserted block (14) and flexible section of thick bamboo (12) and establish spring (15) outside telescopic link (13), two be equipped with between installation piece (5) cultivation dish (6), the inside both sides of cultivation dish (6) all are equipped with T type draw-in groove (11), T type fixture block (16) card is gone into T type draw-in groove (11), the both ends of T type draw-in groove (11) all are equipped with and are located cultivation dish (19) inside, the both sides of cultivation dish (6) all are equipped with fixed U type dog (17), fixed U type dog (17) are gone into in two both ends (18) and insert slot (18).
2. An immune cell in vitro culture device according to claim 1, wherein: a plurality of storage tanks (7) are arranged on the upper end face of the cultivation disk (6), a sealing cover (8) is arranged above the storage tanks (7), and an auxiliary handle is fixedly arranged on the upper end face of the sealing cover (8).
3. An immune cell in vitro culture device according to claim 2, wherein: positioning grooves (10) positioned on the upper end face of the cultivation disk (6) are formed in four end feet of the storage groove (7), positioning blocks (9) are fixedly arranged on four end feet of the sealing cover (8), and the four positioning blocks (9) are clamped into the four positioning grooves (10).
4. An immune cell in vitro culture device according to claim 1, wherein: the inside top of culture apparatus (1) is equipped with temperature regulation lamp (3), the inside both sides of culture apparatus (1) all are equipped with a plurality of LED lamps (4), four terminal feet of culture apparatus (1) below all are equipped with the universal wheel, four the universal wheel all is equipped with the locking piece.
5. An immune cell in vitro culture device according to claim 1, wherein: the top of culture apparatus (1) is equipped with control platform (2), the preceding terminal surface of controlling platform (2) is equipped with control button, the preceding terminal surface of culture apparatus (1) is equipped with sealing door, sealing door's preceding terminal surface is equipped with the handle, sealing door's preceding terminal surface is equipped with the observation window, sealing door with be connected with the hinge between culture apparatus (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320603046.7U CN220265707U (en) | 2023-03-24 | 2023-03-24 | Immune cell in-vitro culture device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320603046.7U CN220265707U (en) | 2023-03-24 | 2023-03-24 | Immune cell in-vitro culture device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220265707U true CN220265707U (en) | 2023-12-29 |
Family
ID=89318077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320603046.7U Active CN220265707U (en) | 2023-03-24 | 2023-03-24 | Immune cell in-vitro culture device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220265707U (en) |
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2023
- 2023-03-24 CN CN202320603046.7U patent/CN220265707U/en active Active
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