CN220194132U - Single Kong Yan type filter for batch adsorption - Google Patents
Single Kong Yan type filter for batch adsorption Download PDFInfo
- Publication number
- CN220194132U CN220194132U CN202321313744.XU CN202321313744U CN220194132U CN 220194132 U CN220194132 U CN 220194132U CN 202321313744 U CN202321313744 U CN 202321313744U CN 220194132 U CN220194132 U CN 220194132U
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- CN
- China
- Prior art keywords
- clamp
- filter
- joint
- main body
- device main
- Prior art date
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- 238000001179 sorption measurement Methods 0.000 title claims abstract description 13
- 238000007789 sealing Methods 0.000 claims abstract description 17
- 229920002943 EPDM rubber Polymers 0.000 claims description 3
- 239000003513 alkali Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 2
- 239000010935 stainless steel Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000006228 supernatant Substances 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 8
- 238000000926 separation method Methods 0.000 abstract description 3
- 239000000499 gel Substances 0.000 description 17
- 239000007788 liquid Substances 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 229960000074 biopharmaceutical Drugs 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000013019 agitation Methods 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000007863 gel particle Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002510 pyrogen Substances 0.000 description 1
Landscapes
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
The utility model relates to a single Kong Yan type filter for batch adsorption, which is used between adsorption and supernatant collection, combines a filter bag with a proper aperture to achieve the purpose of fully intercepting gel, can improve the separation speed and solves the problem that the gel pollutes the next process. The Shan Kongyan filter comprises the following components: device main part (1), clamp (2), blind plate (3) with first flush joint of clamp, joint sealing washer (4), snap ring (5), baffle (6), butterfly head (7), second flush joint of clamp (8).
Description
Technical Field
The utility model relates to the technical field of separation and purification equipment, in particular to a single Kong Yan type filter for batch adsorption.
Background
In the field of biopharmaceuticals, gels are commonly used for batch adsorption purification of proteins of interest. After the gel is stirred and adsorbed in batches, the gel is separated from the feed liquid in a mode of arranging a lower sieve plate under the feed liquid to intercept and filter the gel, and the gel is used for preparing and producing different products. The method is simple and has lower technical requirements, but gel gradually sinks and gathers on the surface of the sieve plate in the process of passing through the lower sieve plate, the sieve plate holes are blocked, the liquid flowing speed is rapidly attenuated, the process step time is long, and the risk of microbial pollution is increased. On the other hand, although the supernatant may be collected from the upper part by siphoning after the agitation adsorption by separating the gel from the liquid, there is a problem in siphoning the partially suspended gel particles to the next step.
Based on this, the present utility model has been proposed.
Disclosure of Invention
The utility model provides a single Kong Yan filter, which is used between adsorption and supernatant collection and is combined with a filter bag with a proper aperture to achieve the purpose of fully intercepting gel, improve the separation speed and solve the problem that the gel pollutes the next process.
The components of the single Kong Yan filter are as follows:
device main part (1), clamp (2), blind plate (3) with first flush joint of clamp, joint sealing washer (4), snap ring (5), baffle (6), butterfly head (7), clamp formula second flush joint (8) (structural schematic view see figure 1).
The device is characterized in that the device body (1), the clamp (2), the blind plate (3) with the clamp type first flat joint, the baffle (6), the butterfly-shaped sealing head (7) and the clamp type second flat joint (8) are made of S316 or S304 stainless steel.
The clamping joint sealing ring (4) is made of high-temperature-resistant, steam-resistant and alkali-resistant materials, preferably ethylene propylene diene monomer rubber and the like.
The clamp (2) connects the blind plate (3) with the clamp type first flat joint and the clamping joint sealing ring (4) with the device main body (1), and the clamping joint sealing ring (4) keeps the connection of the parts in a sealing state;
the supernatant enters the filter from a blind plate (3) with a clamp type flat joint;
the clamping ring (5) is used for fixing a filter bag with a proper aperture, the filter bag does not fall off after the supernatant enters, and the clamping ring is positioned on the diameter of the device main body (1) and has an angle of 33 degrees (the schematic diagram is shown in figure 2);
the baffle plate (6) is welded on the device main body (1) and plays a role in supporting the filter bag, the height of the filter bag can be determined according to the length of the filter bag, and uniform holes are distributed on the baffle plate (6) (the schematic diagram is shown in figure 3);
the butterfly seal head (7) is adopted at the lower part of the main body (1), so that dead angles of equipment are reduced, and cleaning is facilitated;
the clamp type second flat joint (8) is a filter outlet.
The utility model has the beneficial effects that: gel and supernatant can be rapidly separated, the process time is shortened, and the production cost is reduced. Gel is fully intercepted, and the pollution risk of the gel to the next process is reduced.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present utility model;
FIG. 2 is a schematic diagram of a snap ring structure according to the present utility model;
FIG. 3 is a schematic view of a baffle plate according to the present utility model.
In the drawings, the list of components represented by the various numbers is as follows: the device comprises a device main body (1), a clamp (2), a blind plate with a clamp type first flat joint (3), a clamp joint sealing ring (4), a clamp ring (5), a baffle plate (6), a butterfly-shaped sealing head (7) and a clamp type second flat joint (8).
Detailed Description
The principles and features of the present utility model are described below with reference to the drawings, the examples are provided for illustration only and are not intended to limit the scope of the utility model.
The blind plate (3) with the clamp type first flat joint is connected with the device main body (1) through the clamp (2), and the middle is sealed by the clamp joint sealing ring (4), so that liquid leakage is avoided.
When the filter bag net is installed, the clamp (2) is disassembled, the specifications of the filter bag are matched according to the types of gel, the blind plate (3) with the clamp type first flat joint is connected with the siphon pipeline of the batch adsorption tank, and the supernatant mixed with the gel enters the device main body (1) of the filter of the utility model through the flat joint and then flows into the filter bag net fixed on the clamp ring (5).
With the increase of the filtering amount of the supernatant liquid, the gel is gradually accumulated on the filter screen bag, the bearing is gradually increased, and the baffle (6) provides support, so that the filter screen bag can be prevented from falling off from the clamping ring (5).
The gel was intercepted and the supernatant filtered through. And the feed pipe in the next step is connected with a clamp type flat joint (8). The supernatant filtering flow without gel passes through a butterfly end socket (7) and a clamp type second flat joint (8) to enter the next working procedure.
The component of the utility model adopts S316 or S304 and ethylene propylene diene monomer rubber materials, and is resistant to alkali treatment, thereby reducing the biopharmaceutical pyrogen. The design shape is succinct, no dead angle, the cleanness of being convenient for reduces the pollution risk.
Claims (4)
1. A single Kong Yan filter for mass adsorption, comprising:
the device comprises a device main body (1), a clamp (2), a blind plate (3) with a clamp type first flat joint, a clamp joint sealing ring (4), a clamp ring (5), a baffle (6), a butterfly-shaped sealing head (7) and a clamp type second flat joint (8);
the clamp (2) connects the blind plate (3) with the clamp type first flat joint and the clamping joint sealing ring (4) with the device main body (1), and the clamping joint sealing ring (4) keeps the connection of the parts in a sealing state;
the clamping ring (5) is used for fixing the filter bag and is positioned on the diameter of the device main body (1);
the baffle plate (6) is welded on the device main body (1) to play a supporting role on the filter bag, and uniform holes are distributed on the baffle plate (6);
the lower part of the main body (1) adopts a butterfly seal head (7);
the clamp type second flat joint (8) is a filter outlet.
2. The single Kong Yan filter for mass adsorption of claim 1, wherein the device body (1), the clip (2), the blind plate (3) with the clip type first flat connector, the baffle (6), the butterfly head (7), and the clip type second flat connector (8) are made of S316 or S304 stainless steel.
3. The single Kong Yan filter for mass adsorption according to claim 1 or 2, wherein the bayonet sealing ring (4) is made of a material resistant to high temperature, water vapor and alkali.
4. A single Kong Yan filter for mass adsorption according to claim 3, wherein the bayonet sealing ring (4) is made of ethylene propylene diene monomer rubber.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202321313744.XU CN220194132U (en) | 2023-05-26 | 2023-05-26 | Single Kong Yan type filter for batch adsorption |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202321313744.XU CN220194132U (en) | 2023-05-26 | 2023-05-26 | Single Kong Yan type filter for batch adsorption |
Publications (1)
Publication Number | Publication Date |
---|---|
CN220194132U true CN220194132U (en) | 2023-12-19 |
Family
ID=89146133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202321313744.XU Active CN220194132U (en) | 2023-05-26 | 2023-05-26 | Single Kong Yan type filter for batch adsorption |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN220194132U (en) |
-
2023
- 2023-05-26 CN CN202321313744.XU patent/CN220194132U/en active Active
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