CN220183197U - Circulating tumor cell enrichment experiment box - Google Patents
Circulating tumor cell enrichment experiment box Download PDFInfo
- Publication number
- CN220183197U CN220183197U CN202321564283.3U CN202321564283U CN220183197U CN 220183197 U CN220183197 U CN 220183197U CN 202321564283 U CN202321564283 U CN 202321564283U CN 220183197 U CN220183197 U CN 220183197U
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- CN
- China
- Prior art keywords
- box body
- fixedly connected
- tumor cell
- circulating tumor
- wall
- Prior art date
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- 208000005443 Circulating Neoplastic Cells Diseases 0.000 title claims abstract description 21
- 238000002474 experimental method Methods 0.000 title claims abstract description 12
- 230000007246 mechanism Effects 0.000 claims abstract description 29
- 238000010438 heat treatment Methods 0.000 claims abstract description 26
- 239000010445 mica Substances 0.000 claims abstract description 11
- 229910052618 mica group Inorganic materials 0.000 claims abstract description 11
- 238000001816 cooling Methods 0.000 claims description 14
- 239000000428 dust Substances 0.000 claims description 12
- 239000004065 semiconductor Substances 0.000 claims description 12
- 238000009434 installation Methods 0.000 claims description 9
- 238000012360 testing method Methods 0.000 claims description 8
- 239000004519 grease Substances 0.000 claims description 6
- 229920001296 polysiloxane Polymers 0.000 claims description 6
- 239000002390 adhesive tape Substances 0.000 claims description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 4
- 229910052782 aluminium Inorganic materials 0.000 claims description 4
- 238000005192 partition Methods 0.000 claims description 4
- 239000004576 sand Substances 0.000 claims description 4
- 238000003149 assay kit Methods 0.000 claims 9
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 210000004027 cell Anatomy 0.000 abstract description 5
- 210000004881 tumor cell Anatomy 0.000 abstract description 4
- 230000009467 reduction Effects 0.000 abstract description 2
- 238000011160 research Methods 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 238000009423 ventilation Methods 0.000 description 3
- 238000005057 refrigeration Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000007664 blowing Methods 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
- Y02B30/00—Energy efficient heating, ventilation or air conditioning [HVAC]
Landscapes
- Devices For Use In Laboratory Experiments (AREA)
Abstract
The utility model discloses a circulating tumor cell enrichment experiment box, which relates to the technical field of tumor cell experiments, and the technical scheme is as follows: including the box body, the inside fixedly connected with baffle of box body, the baffle top is equipped with adjustable rack of placing height, but baffle bottom is equipped with the drawer of outside pull-out, drawer internally mounted has centrifuge, the inside top both ends of box body are equipped with heating mechanism and refrigerating mechanism respectively, heating mechanism includes fan, ring and mica frame, mounting groove a has been seted up to box body top one end, the inner wall top at mounting groove a is fixed to the fan, the ring is fixed in the inner wall bottom of mounting groove a, the beneficial effect of a circulating tumor cell enrichment experiment box is: according to the utility model, the heating mechanism and the refrigerating mechanism are arranged, so that the temperature rise and the temperature reduction treatment can be respectively carried out on the inside of the box body, the corresponding temperature regulation function can be provided according to the living environment of different circulating tumor cells, and the utility model can be expanded to other cell research fields and has strong universality.
Description
Technical Field
The utility model relates to the technical field of tumor cell experiments, in particular to a circulating tumor cell enrichment experiment box.
Background
The Chinese patent with publication number of CN210427592U discloses a circulating tumor cell enrichment experiment box, wherein the heating pipe is used for heating distilled water in the water pipe to achieve the heating effect of the upper cavity; and a centrifugal machine is arranged and fixed in the lower cavity, the tumor cells are centrifuged by the centrifugal machine, and then the tumor cells are placed in the upper cavity for storage, so that the contact with the external environment is reduced as much as possible.
However, when the device is used, the device only has the heating and temperature rising functions, and does not have the refrigerating and temperature lowering functions, so that a proper environment cannot be provided for a cell sample well, meanwhile, the centrifugal machine is fixedly arranged in the lower cavity, and the centrifugal machine needs to be operated in the box body during centrifugation, so that the movable space is limited, and improvement is needed.
Disclosure of Invention
Therefore, the utility model provides a circulating tumor cell enrichment experiment box, which can adjust proper temperature according to the requirement of a cell sample by arranging a refrigerating mechanism and a heating mechanism, and can pull out a centrifugal machine outwards by arranging a movable drawer, thereby being convenient for operation and solving the problems in the background technology.
In order to achieve the above object, the present utility model provides the following technical solutions: the utility model provides a circulating tumor cell enrichment experiment box, includes the box body, the inside fixedly connected with baffle of box body, the baffle top is equipped with adjustable rack of placing height, the baffle bottom is equipped with the drawer that can outwards pull out, drawer internally mounted has the centrifuge, the inside both ends of top are equipped with heating mechanism and refrigerating mechanism respectively;
the heating mechanism comprises a fan, a circular ring and a mica frame, wherein one end of the top of the box body is provided with a mounting groove a, the fan is fixed on the top of the inner wall of the mounting groove a, the circular ring is fixed at the bottom of the inner wall of the mounting groove a, the mica frame is fixedly connected with the inner wall of the circular ring, heating wires are uniformly wound on the mica frame, and the inner bottom wall of the mounting groove a is fixedly connected with a grid air port a;
the cooling mechanism comprises a connecting ring, a supporting plate, a radiator and a cooling fan, wherein the top of the box body is far away from one end of the installation groove a and is provided with an installation groove b, the connecting ring is fixedly connected with the inner wall of the installation groove b, the supporting plate is fixedly connected with the inner wall of the connecting ring, a semiconductor cooling piece is fixedly embedded in the middle of the supporting plate, the top of the semiconductor cooling piece is adhered with a heat conduction aluminum sheet through heat conduction silicone grease, the bottom of the semiconductor cooling piece is adhered with a heat conduction block through heat conduction silicone grease, the radiator is fixedly arranged at the top of the supporting plate, the cooling fan is fixedly connected with the bottom of the inner wall of the installation groove b, and a grid air port b is fixedly connected with the inner bottom wall of the installation groove b.
Preferably, a door body is arranged on one side of the box body, one side of the door body is hinged with the box body, and the door body is connected with the box body through a magnetic adhesive tape.
Preferably, the uniform body in test-tube rack both ends is connected with the sand grip, at least two slide ways that supply the sand grip to slide have all been seted up to box body both ends inner wall.
Preferably, the ends of the two raised strips are fixedly embedded with a magnetic block a, the positions of the inner wall of one side of the box body corresponding to the sliding groove ports are fixedly embedded with a magnetic block b, and the magnetic block b and the magnetic block a are magnetically adsorbed.
Preferably, one side of the drawer is fixedly connected with a handle, and the other side of the drawer is in an opening shape.
Preferably, the sleeve is fixedly connected with two ends of the top of the box body, and the grid net is fixedly connected with the top of the sleeve.
Preferably, the top of the sleeve is provided with a dust cover, and the dust cover is in threaded connection with the sleeve.
Preferably, a handle is fixedly connected to one side of the top of the box body.
Preferably, a temperature and humidity sensor is fixedly connected to the inner top wall of the box body.
Preferably, the door body is fixedly embedded with a control panel, the temperature and humidity sensor is electrically connected with the control panel, and the control panel is used for displaying temperature and humidity data in the box body in real time and can respectively control the heating mechanism and the refrigerating mechanism.
The embodiment of the utility model has the following advantages:
1. according to the utility model, the heating mechanism and the refrigerating mechanism are arranged, so that the temperature rise and the temperature reduction treatment can be respectively carried out on the inside of the box body, the corresponding temperature regulation function can be provided according to the living environment of different circulating tumor cells, and the utility model can be expanded to other cell research fields and has strong universality.
2. According to the utility model, the movable drawer is arranged, and one side of the drawer is also provided with the opening, so that the drawer can be pulled out of the box body to operate when the centrifugal machine is needed, the centrifugal machine is not far away from the box body, the contact between a cell sample and the external environment is reduced, and a wider operation space is provided, so that the practicability is strong.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It will be apparent to those skilled in the art from this disclosure that the drawings described below are merely exemplary and that other embodiments may be derived from the drawings provided without undue effort.
The structures, proportions, sizes, etc. shown in the present specification are shown only for the purposes of illustration and description, and are not intended to limit the scope of the utility model, which is defined by the claims, so that any structural modifications, proportional changes, or adjustments of size, which do not affect the efficacy of the utility model or the objects achieved, should fall within the scope of the utility model.
FIG. 1 is a schematic view of the overall structure provided by the present utility model;
FIG. 2 is an exploded view of a partial structure according to the present utility model;
FIG. 3 is a diagram showing the internal structure of the case provided by the utility model;
FIG. 4 is an exploded view of the top structure of the case provided by the present utility model;
fig. 5 is an enlarged view of the structure of the portion a in fig. 4 according to the present utility model.
In the figure: 1. a case body; 2. a partition plate; 3. a test tube rack; 4. a drawer; 5. a centrifuge; 6. a blower; 7. a circular ring; 8. a mica frame; 9. a heating wire; 10. a grille tuyere a; 11. a connecting ring; 12. a support plate; 13. a heat sink; 14. a heat radiation fan; 15. a semiconductor refrigeration sheet; 16. a heat conducting aluminum sheet; 17. a cold guide block; 18. a grille tuyere b; 19. a door body; 20. a convex strip; 21. a chute; 22. a magnetic block a; 23. a magnetic block b; 24. a sleeve; 25. a dust cover; 26. a handle; 27. a temperature and humidity sensor; 28. and a control panel.
Detailed Description
Other advantages and advantages of the present utility model will become apparent to those skilled in the art from the following detailed description, which, by way of illustration, is to be read in connection with certain specific embodiments, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-5, the circulating tumor cell enrichment experiment box provided by the utility model comprises a box body 1, wherein a baffle plate 2 is fixedly connected inside the box body 1, a test tube rack 3 with adjustable placing height is arranged at the top of the baffle plate 2, a drawer 4 capable of being pulled out is arranged at the bottom of the baffle plate 2, a centrifugal machine 5 is arranged inside the drawer 4, and heating mechanisms and refrigerating mechanisms are respectively arranged at two ends of the inner top of the box body 1;
the heating mechanism comprises a fan 6, a circular ring 7 and a mica frame 8, wherein a mounting groove a is formed in one end of the top of the box body 1, the fan 6 is fixed on the top of the inner wall of the mounting groove a, the circular ring 7 is fixed at the bottom of the inner wall of the mounting groove a, the mica frame 8 is fixedly connected with the inner wall of the circular ring 7, heating wires 9 are uniformly wound on the mica frame 8, and a grid air port a10 is fixedly connected with the inner bottom wall of the mounting groove a;
the refrigerating mechanism comprises a connecting ring 11, a supporting plate 12, a radiator 13 and a cooling fan 14, wherein one end, far away from a mounting groove a, of the top of the box body 1 is provided with a mounting groove b, the connecting ring 11 is fixedly connected with the inner wall of the mounting groove b, the supporting plate 12 is fixedly connected with the inner wall of the connecting ring 11, a plurality of ventilation grooves are uniformly formed in the supporting plate 12, a semiconductor refrigerating sheet 15 is fixedly embedded in the middle of the supporting plate 12, the top of the semiconductor refrigerating sheet 15 is adhered with a heat conducting aluminum sheet 16 through heat conducting silicone grease, the bottom of the semiconductor refrigerating sheet 15 is adhered with a heat conducting block 17 through heat conducting silicone grease, the radiator 13 is fixedly arranged at the top of the supporting plate 12, the cooling fan 14 is fixedly connected with the bottom of the inner wall of the mounting groove b, and the inner bottom wall of the mounting groove b is fixedly connected with a grid air port b18;
in this embodiment, the inside of the casing constituting the case 1 is provided with a heat-insulating interlayer.
In order to achieve the aim of sealing protection, the device is realized by adopting the following technical scheme: a door body 19 is arranged on one side of the box body 1, one side of the door body 19 is hinged with the box body 1, the door body 19 is connected with the box body 1 through a magnetic adhesive tape, the magnetic adhesive tape is in a frame shape and is matched with the box body 1, and the refrigerator door can be referred to for specific structure in the prior art;
in order to achieve the purpose of stable connection, the device is realized by adopting the following technical scheme: the two ends of the test tube rack 3 are integrally connected with raised strips 20, the inner walls of the two ends of the box body 1 are provided with at least two sliding grooves 21 for the raised strips 20 to slide, the ends of the two raised strips 20 are fixedly embedded with magnetic blocks a22, the positions, corresponding to the ports of the sliding grooves 21, of the inner walls of one side of the box body 1 are fixedly embedded with magnetic blocks b23, the magnetic blocks b23 and the magnetic blocks a22 are magnetically adsorbed, the placing height of the test tube rack 3 can be adjusted according to the lengths of test tubes through the plurality of sliding grooves 21, and the test tube rack 3 can be more stable in placing and cannot easily slip through the magnetic blocks b23 and the magnetic blocks a 22;
in order to achieve the purpose of being convenient to operate, the device is achieved by adopting the following technical scheme: one side of the drawer 4 is fixedly connected with a handle, the other side of the drawer 4 is in an opening shape, and the opening shape is designed to be more convenient for operating the centrifugal machine 5;
in order to achieve the purposes of ventilation and sealing, the device is achieved by adopting the following technical scheme: the two ends of the top of the box body 1 are fixedly connected with sleeves 24, the tops of the sleeves 24 are fixedly connected with grid nets, dust covers 25 are arranged at the tops of the sleeves 24, threads are uniformly formed on the outer walls of the tops of the sleeves 24 and the inner walls of the dust covers 25, the dust covers 25 are in threaded connection with the sleeves 24, the two sleeves 24 respectively correspond to a mounting groove a and a mounting groove b, the grid nets are used for air suction and ventilation of a refrigerating mechanism and a heating mechanism in use, and the dust covers 25 are used for dust protection in idle;
in order to achieve the purpose of portability, the device is achieved by adopting the following technical scheme: a handle 26 is fixedly connected to one side of the top of the box body 1;
in order to achieve the aim of being convenient to operate and control, the device is achieved by adopting the following technical scheme: the inner top wall of the box body 1 is fixedly connected with a temperature and humidity sensor 27, a control panel 28 is fixedly embedded in the door body 19, the temperature and humidity sensor 27 is electrically connected with the control panel 28, and the control panel 28 is used for displaying temperature and humidity data in the box body 1 in real time and can respectively control a heating mechanism and a refrigerating mechanism.
The application process of the utility model is as follows: when heating is needed, firstly unscrewing the dust cover 25 of the sleeve 24 corresponding to the top of the mounting groove a, then starting the fan 6 through the control panel 28, electrifying the heating wire, and blowing the heat of the heating wire 9 to the box body 1 by the fan 6 so as to improve the internal temperature of the box body 1; when refrigeration is needed, the dust cover 25 of the sleeve 24 corresponding to the top of the mounting groove b can be unscrewed, then the radiator 13 and the cooling fan 14 are started through the control panel 28, and the semiconductor refrigerating sheet 15 is electrified, the radiator 13 blows cold air of the semiconductor refrigerating sheet 15 to the cooling fan 14, and the cooling fan 14 blows the cold air into the box body 1, so that the cooling of the box body 1 can be realized.
The above description is of the preferred embodiments of the present utility model, and any person skilled in the art may modify the present utility model or make modifications to the present utility model with the technical solutions described above. Therefore, any simple modification or equivalent made according to the technical solution of the present utility model falls within the scope of the protection claimed by the present utility model.
Claims (10)
1. The utility model provides a circulating tumor cell enrichment experiment box, includes box body (1), its characterized in that: the device is characterized in that a partition plate (2) is fixedly connected inside the box body (1), a test tube rack (3) with adjustable placing height is arranged at the top of the partition plate (2), a drawer (4) capable of being pulled out outwards is arranged at the bottom of the partition plate (2), a centrifugal machine (5) is arranged inside the drawer (4), and heating mechanisms and refrigerating mechanisms are respectively arranged at two ends of the inner top of the box body (1);
the heating mechanism comprises a fan (6), a circular ring (7) and a mica frame (8), wherein an installation groove a is formed in one end of the top of the box body (1), the fan (6) is fixed at the top of the inner wall of the installation groove a, the circular ring (7) is fixed at the bottom of the inner wall of the installation groove a, the mica frame (8) is fixedly connected with the inner wall of the circular ring (7), heating wires (9) are uniformly wound on the mica frame (8), and a grid air port a (10) is fixedly connected with the inner bottom wall of the installation groove a;
the refrigerating mechanism comprises a connecting ring (11), a supporting plate (12), a radiator (13) and a cooling fan (14), wherein the top of the box body (1) is far away from one end of a mounting groove a and is provided with a mounting groove b, the connecting ring (11) is fixedly connected with the inner wall of the mounting groove b, the supporting plate (12) is fixedly connected with the inner wall of the connecting ring (11), a semiconductor refrigerating sheet (15) is fixedly embedded in the middle of the supporting plate (12), a heat conducting aluminum sheet (16) is adhered to the top of the semiconductor refrigerating sheet (15) through heat conducting silicone grease, a heat conducting block (17) is adhered to the bottom of the semiconductor refrigerating sheet (15) through heat conducting silicone grease, the radiator (13) is fixedly arranged at the top of the supporting plate (12), the cooling fan (14) is fixedly connected with the bottom of the inner wall of the mounting groove b, and a grid air outlet b (18) is fixedly connected with the inner bottom wall of the mounting groove b.
2. The circulating tumor cell enrichment assay kit of claim 1, wherein: the novel box is characterized in that a door body (19) is arranged on one side of the box body (1), one side of the door body (19) is hinged to the box body (1), and the door body (19) is connected with the box body (1) through a magnetic adhesive tape.
3. The circulating tumor cell enrichment assay kit of claim 1, wherein: the test tube rack (3) both ends homogeneity body coupling has sand grip (20), at least two slide ways (21) that supply sand grip (20) to slide have all been seted up to box body (1) both ends inner wall.
4. A circulating tumor cell enrichment assay kit according to claim 3, wherein: the ends of the two raised strips (20) are fixedly embedded with magnetic blocks a (22), the positions, corresponding to the ports of the sliding grooves (21), of the inner wall of one side of the box body (1) are fixedly embedded with magnetic blocks b (23), and the magnetic blocks b (23) and the magnetic blocks a (22) are magnetically adsorbed.
5. The circulating tumor cell enrichment assay kit of claim 1, wherein: one side of the drawer (4) is fixedly connected with a handle, and the other side of the drawer (4) is in an opening shape.
6. The circulating tumor cell enrichment assay kit of claim 1, wherein: sleeve (24) are fixedly connected to two ends of the top of the box body (1), and grid nets are fixedly connected to the top of the sleeve (24).
7. The circulating tumor cell enrichment assay kit of claim 6, wherein: the top of the sleeve (24) is provided with a dust cover (25), and the dust cover (25) is in threaded connection with the sleeve (24).
8. The circulating tumor cell enrichment assay kit of claim 1, wherein: a handle (26) is fixedly connected to one side of the top of the box body (1).
9. The circulating tumor cell enrichment assay kit of claim 2, wherein: the inner top wall of the box body (1) is fixedly connected with a temperature and humidity sensor (27).
10. The circulating tumor cell enrichment assay kit of claim 9, wherein: the door body (19) is fixedly embedded with a control panel (28), the temperature and humidity sensor (27) is electrically connected with the control panel (28), and the control panel (28) is used for displaying temperature and humidity data in the box body (1) in real time and can respectively control the heating mechanism and the refrigerating mechanism.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321564283.3U CN220183197U (en) | 2023-06-19 | 2023-06-19 | Circulating tumor cell enrichment experiment box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321564283.3U CN220183197U (en) | 2023-06-19 | 2023-06-19 | Circulating tumor cell enrichment experiment box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220183197U true CN220183197U (en) | 2023-12-15 |
Family
ID=89104003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321564283.3U Active CN220183197U (en) | 2023-06-19 | 2023-06-19 | Circulating tumor cell enrichment experiment box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220183197U (en) |
-
2023
- 2023-06-19 CN CN202321564283.3U patent/CN220183197U/en active Active
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