CN220181635U

CN220181635U - Biological sample storage library

Info

Publication number: CN220181635U
Application number: CN202321611967.4U
Authority: CN
Inventors: 王杰; 刘占杰; 赵洪滨; 谢玉刚; 刘辉
Original assignee: Qingdao Haier Biomedical Co Ltd
Current assignee: Qingdao Haier Biomedical Co Ltd
Priority date: 2023-06-21
Filing date: 2023-06-21
Publication date: 2023-12-15
Anticipated expiration: 2033-06-21

Abstract

The utility model belongs to the technical field of biological sample storage, and particularly provides a biological sample storage library. The automatic storage device aims at solving the problem that the sample is easy to damage due to tube picking operation in the process of storing and taking the frozen storage tubes of the existing automatic storage device. The biological sample storage warehouse comprises a box body, a lifting and transferring device, a code scanning device, a tube picking device and a freezing box transferring device, wherein a storage room, a tube picking room and a sample receiving room are arranged in the box body, the tube picking room is communicated with the storage room, the upper part of the tube picking room in the sample receiving room is communicated with the tube picking room through a first inlet and a second inlet, and the sample receiving room is communicated with the external environment of the box body through a second inlet and a second outlet; the lifting and transferring device is arranged in the sample receiving room; the code scanning device, the tube picking device and the frozen box transferring device are arranged in the tube picking room. The tube picking and storing room is communicated, so that the temperatures of the tube picking and storing room are consistent, a sample cannot be deactivated in the tube picking operation process, and the sample deactivation risk is reduced.

Description

Biological sample storage library

Technical Field

The utility model belongs to the technical field of biological sample storage, and particularly provides a biological sample storage library.

Background

The development of life science research and the progress of disease analysis detection and treatment and health care technologies in the clinical medical field have promoted the increasingly wide demand for biological samples, and have also put higher demands on the storage technology and equipment of biological samples, including demands on the safety, reliability and stability of stored samples, and the accuracy, efficiency and scientificity of sample access processes and procedures. Long-term storage of biological samples generally requires the use of as low a temperature as possible to reduce the biochemical reactions within the sample and to increase the stability of the various components within the sample. The development and use of automated cryogenic or ultra-cryogenic biological sample access devices is a necessary development in order to achieve long-term, stable, reliable storage and sampling of large volumes of biological samples.

The existing automated storage equipment for low-temperature storage generally comprises a cache area and a main library area, wherein the cache area is used for receiving the frozen storage boxes and picking and managing the frozen storage pipes into the corresponding frozen storage boxes through a pipe picking device. However, in the existing buffer area, since the sample is conveyed by being communicated with the external environment, in order to ensure smooth operation of the internal device and avoid the frosting phenomenon in the buffer area from being reduced in the process of transferring the freezing box by being communicated with the external environment, the temperature difference between the buffer area and the external environment area needs to be reduced, so that the temperature in the buffer area is generally set to be minus 20 ℃ or minus 30 ℃.

However, when the tube picking operation is required, the time required for the tube picking operation is long, which can prolong the storage time of the frozen tube in the buffer area, and the frozen tube stays in the buffer area at minus 30 ℃ or above for a long time, so that the sample is easy to deteriorate, and the loss is caused.

Accordingly, there is a need in the art for a new solution to the above-mentioned technical problems.

Disclosure of Invention

The utility model aims to solve the technical problems, namely the problem that the sample is easy to damage due to tube picking operation in the process of storing and taking the frozen tube by the existing automatic storage equipment.

The utility model provides a biological sample storage library, which comprises a box body, wherein a storage room, a picking pipe room and a sample receiving room are arranged in the box body, the picking pipe room is communicated with the storage room and distributed along the Y-axis direction, the sample receiving room is positioned above the picking pipe room and is communicated with the picking pipe room through a first inlet and a second inlet, and the sample receiving room is communicated with the external environment of the box body through a second inlet and a second outlet; a lifting and transferring device arranged in the sample receiving room, wherein the lifting and transferring device is arranged to transfer the freezing box between the picking pipe room and the sample receiving room through the first inlet and outlet, and is also arranged to transfer the freezing box between the sample receiving room and the outside through the second inlet and outlet; the code scanning device is arranged in the tube picking room and is used for scanning a box code of the freezing box and a tube code of the freezing tube in the freezing box; the tube picking device is arranged in the tube picking room and is used for picking tubes; and the frozen box transferring equipment is arranged in the picking pipe room and is arranged to be capable of transferring frozen boxes among the lifting transferring device, the picking pipe equipment, the code scanning device and the storage room.

In a preferred technical solution of the biological sample storage library, the lifting and transferring device comprises a first fixing piece, a lifting mechanism, a transferring frame and a first horizontal transferring mechanism, wherein the first fixing piece is installed in the sample receiving room, the lifting mechanism and the first horizontal transferring mechanism are installed on the first fixing piece and are positioned in the sample receiving room, the transferring frame is connected with the lifting mechanism and is arranged through the first inlet and outlet, the transferring frame can be used for placing frozen storage boxes in batches, and the lifting mechanism is arranged to drive the transferring frame to move along a Z axis so that the transferring frame moves between a first transferring position and a second transferring position, the first transferring position is positioned in the sample receiving room, and the second transferring position is positioned in the picking pipe room; the first horizontal transfer mechanism is arranged to be capable of receiving and transferring the frozen storage box along the X axis, wherein in the condition that the transfer frame is located at the first transfer position, the transfer frame and the second inlet and outlet are arranged opposite to each other, the first horizontal transfer mechanism is capable of receiving the frozen storage box located on the transfer frame and conveying the frozen storage box to the external environment through the second inlet and outlet, and receiving the frozen storage box in the external environment through the second inlet and outlet and placing the frozen storage box on the transfer frame.

In the preferred technical scheme of the biological sample storage library, the transfer rack comprises a rack body, a plurality of storage positions are arranged in the rack body, the storage positions are arranged in an array along the length direction and the height direction of the rack body and form a plurality of rows and a plurality of layers, each storage position is provided with a first opening and a second opening for taking and placing the freezing storage box, and the first opening and the second opening are oppositely arranged.

In the preferred technical scheme of the biological sample storage library, a first sealing element and a second sealing element are respectively arranged at the top and the bottom of the transfer frame, the lifting mechanism is connected with the first sealing element, the first sealing element seals the first inlet and the outlet when the transfer frame is positioned at the second transfer position, and the second sealing element seals the first inlet and the outlet when the transfer frame is positioned at the first transfer position.

In the preferred technical scheme of the biological sample storage library, the biological sample storage library further comprises a transfer frame guiding device, wherein the transfer frame guiding device is positioned in the picking pipe room, and the transfer frame guiding device is connected with the transfer frame and can guide the transfer frame in the process of moving up and down of the transfer frame so as to enable the transfer frame to linearly move.

In the preferred technical scheme of the biological sample storage warehouse, the biological sample storage warehouse further comprises a detection piece, the detection piece is arranged at the top of the transport frame guiding device, the detection piece is horizontally arranged towards the transport frame, and the detection piece can detect whether a freezing storage box exists at the storage position with the same height.

In the preferred technical scheme of the biological sample storage library, the number of the detecting pieces is multiple, the detecting pieces are distributed at intervals along the length direction of the transport frame, and each row of storage positions corresponds to one detecting piece.

In a preferred technical solution of the biological sample storage library, the frozen storage box transferring device comprises a first frozen storage box receiving and transferring device and a second frozen storage box receiving and transferring device, wherein the first frozen storage box receiving and transferring device is arranged to be capable of receiving and transferring frozen storage boxes along an X axis and a Y axis, and the first frozen storage box receiving and transferring device can be respectively in butt joint with the lifting and transferring device, the picking pipe device, the code scanning device and the second frozen storage box receiving and transferring device so as to receive and transfer frozen storage boxes; the second cryopreservation cassette receiving and transporting device is configured to enable transfer of a cryopreservation cassette between the first cryopreservation cassette receiving and transporting device and the storage compartment.

In the preferred technical solution of the biological sample storage library, the first freezing storage box receiving and transferring device comprises a first mounting piece, a first lifting mechanism, a second mounting piece, a first horizontal sliding mechanism, a third mounting piece, a rotary shovel disk mechanism and a second horizontal transferring mechanism, wherein the first lifting mechanism, the second mounting piece, the first horizontal sliding mechanism, the third mounting piece, the rotary shovel disk mechanism and the second horizontal transferring mechanism are mounted on the first mounting piece; the first mounting piece is connected with the box body, the second mounting piece is connected with the first lifting mechanism, the first horizontal sliding mechanism and the second horizontal transferring mechanism are mounted on the second mounting piece, the first horizontal sliding mechanism and the second horizontal transferring mechanism are distributed at intervals along an X axis, the third mounting piece is connected with the first horizontal sliding mechanism, the rotary shovel disc mechanism is mounted on the third mounting piece, and the first lifting mechanism is arranged to drive the second mounting piece, the first horizontal sliding mechanism, the second horizontal transferring mechanism, the third mounting piece and the rotary shovel disc mechanism to move along a Z axis; the first horizontal sliding mechanism is arranged to drive the third mounting piece and the rotary shovel disk mechanism to move along the Y axis, so that the rotary shovel disk mechanism can be in butt joint with the pipe picking device to transfer the freezing box; the rotary shovel disc mechanism is arranged to be capable of rotating circumferentially around the vertical shaft and moving telescopically along the length direction of the rotary shovel disc mechanism so as to receive and transfer the freezing box; the second horizontal transfer mechanism is arranged to be capable of receiving and transferring the cryopreservation box along the Y axis and transferring the cryopreservation box among the tube picking equipment, the code scanning device and the second cryopreservation box receiving and transferring device.

In the preferred technical scheme of the biological sample storage library, the code scanning device and the second horizontal transfer mechanism are distributed along the Y-axis at intervals, and the first lifting mechanism drives the second horizontal transfer mechanism to move to the same height as the code scanning device, and the second horizontal transfer mechanism and the code scanning device are opposite to each other.

In a preferred embodiment of the above biological sample storage library, the second freezing storage box receiving and transferring device includes a first support member, a second horizontal sliding mechanism mounted on the first support member, a second support member, and a box carrying member; the second support piece is arranged on the second horizontal sliding mechanism, the box carrying piece is arranged on the second support piece, and the box carrying piece can carry the freezing box; the second horizontal sliding mechanism is arranged to drive the second supporting piece and the box carrying piece to move along a Y axis so as to transfer the freezing box between the picking pipe and the storage room, the box carrying piece and the second horizontal transfer mechanism are distributed at intervals along the Y axis, and the first lifting mechanism is arranged opposite to the box carrying piece under the condition that the second horizontal transfer mechanism is driven to move to the same height as the box carrying piece; and/or the tube picking device comprises a third horizontal sliding mechanism, a freezing box fixing mechanism and a tube picking device, wherein the first freezing box receiving and transferring device, the second horizontal sliding mechanism and the code scanning device are sequentially arranged along a Y axis, the tube picking device and the code scanning device are distributed at intervals along an X axis, and the freezing box fixing mechanism can fix two freezing boxes at the same time; the third horizontal sliding mechanism and the tube picking device are connected with the box body, and the freezing box fixing mechanism is arranged on the third horizontal sliding mechanism; the third horizontal sliding mechanism is arranged to drive the freezing box fixing mechanism to move along the X axis so as to enable the freezing box fixing mechanism to move among a first box receiving position, a second box receiving position and a tube picking position; the freezing box fixing mechanism can be in butt joint with the rotary shovel disc mechanism at the first box connecting position and can be in butt joint with the second horizontal transferring mechanism at the second box connecting position so as to receive and transfer the freezing box; the tube picking device is arranged to be capable of picking the frozen box on the frozen box fixing mechanism at the tube picking position.

In the preferred technical scheme of the biological sample storage library, the tube picking device further comprises a tube jacking device, and the tube jacking device is arranged to eject out frozen storage tubes in the frozen storage boxes on the frozen storage box fixing mechanism at the tube picking position, so that the tube picking device picks the tubes smoothly.

In the preferred technical scheme of the biological sample storage library, the jacking device comprises a third connecting piece, a third lifting mechanism and a jacking pipe fitting; the third connecting piece with choosing pipe clamp claw is connected, third elevating system installs on the third connecting piece, the push pipe spare with third elevating system is connected, third elevating system sets up to can drive push pipe spare moves along the Z axle, the push pipe head of push pipe spare is located choosing pipe clamp claw under and with choosing pipe clamp claw just to setting.

In the preferred technical scheme of the biological sample storage library, the environmental temperature between the picking tube and the storage room is 70 ℃ below zero to 120 ℃ below zero; and/or the ambient temperature within the sample receiving compartment is from-10 ℃ to-30 ℃.

In the preferred technical scheme of the biological sample storage library, the number of the storage rooms is two, and the picking pipe is arranged between the two storage rooms.

In the preferred technical scheme of the biological sample storage library, the refrigeration systems between the picking pipes and in the storage room are air-cooled refrigeration systems.

Under the condition that the technical scheme is adopted, the biological sample storage warehouse comprises a box body, a lifting and transferring device, a code scanning device, a tube picking device and a freezing storage box transferring device, wherein a storage room, a tube picking room and a sample receiving room are arranged in the box body, the tube picking room is communicated with the storage room, the sample receiving room is positioned above the tube picking room, the lifting and loading device is used for transferring the freezing storage box between the sample receiving room and the tube picking room, and the freezing storage box transferring device is used for transferring the freezing storage box between the lifting and transferring device, the tube picking device, the code scanning device and the storage room; the arrangement mode is that firstly, the tube picking and storing room is communicated, the temperature between the tube picking and storing room is consistent, the sample is not inactivated in the tube picking operation process, and the sample inactivation risk is reduced; secondly, the sample receiving room is arranged above the picking pipe room, and the picking pipe room and the storage room are distributed along the horizontal direction, so that the distribution is reasonable, the structure is compact, the volume of the biological sample storage room is reduced, and the application is convenient; third, freeze case transfer equipment comes to freeze the case and promotes transfer device, select the pipe equipment, select between pipe device and the storage to realize freezing the automatic access of case, can reduce the box in and select the duty cycle between the pipe, thereby be favorable to improving the storage utilization ratio in the box.

Further, the lifting and transferring device comprises a lifting mechanism, a transferring frame and a first horizontal transferring mechanism, wherein the transferring frame can be used for placing frozen boxes in batches, the lifting mechanism can drive the transferring frame to move along the vertical direction so that the transferring frame can move between a first transferring position and a second transferring position, and the first horizontal transferring mechanism can receive and transfer the frozen boxes along an X axis; the arrangement mode is first, the structure is simple, and the arrangement is convenient; secondly, the transfer rack can transfer the frozen boxes in batches at one time, so that the transfer efficiency of the frozen boxes is improved, and the frozen boxes are more convenient to use; third, the first horizontal transfer mechanism can receive and transfer the cryopreserved box along the X axis, so that the cryopreserved box is automatically transferred between the outside and the transfer frame.

Still further, transport the frame and include the support body, be provided with a plurality of storage positions that are multiseriate and multilayer matrix distribution in the support body to every storage position's both ends all have first opening and second opening, and first opening and second opening all can deposit the cryopreserved box to storage position on, such setting, simple structure, small, and can both realize the deposit of cryopreserved box in every storage position's the two directions, more convenient application.

Still further, the top and the bottom of transporting the frame are provided with respectively and are used for sealing first import and export first sealing member and second sealing member, and such setting mode, transport the frame and be in first transfer position and when external receipt freezes the case, the second sealing member seals first import and export first, transport the frame and be in second transfer position and take intraductal butt joint transfer freezes the case in the pipe, first sealing member seals first import and export, can avoid taking the cold air between the pipe to get into in the sample receiving room through first import and export, make the environment in the pipe of choosing keep stable, reduce the cold consumption.

Still further, set up in choosing the intraductal complex of frame guider that transports with transporting, to transporting the frame and leading when transporting the frame reciprocates, such setting up mode guarantees to transport the frame and make rectilinear movement to can make to transport the frame and keep stable not rocking at the removal in-process, help improving the transportation factor of safety of freezing the case, more facilitate the use.

Still further, be provided with the horizontal detection piece towards the transportation frame on transportation frame guider to whether there is the cryopreservation box in the storage position that can detect the transportation frame, more convenient application.

Still further, set up the detection piece into a plurality ofly, make every detection piece correspond a row of storage position, can effectually detect every row of storage position of transporting the frame, it is more convenient to use.

Still further, the frozen storage box transferring equipment is set to a first frozen storage box receiving and transferring device and a second frozen storage box receiving and transferring device, wherein the first frozen storage box receiving and transferring device can transfer frozen storage boxes among the lifting and shipping device, the pipe picking equipment, the code scanning device and the second frozen storage box receiving and transferring device, and the second frozen storage box receiving and transferring device can transfer frozen storage boxes among the first frozen storage box receiving and transferring device and the storage room; the arrangement mode enables the first freezing box receiving and transferring device to be capable of butting two perpendicular directions to receive and transfer the freezing boxes, is more convenient to apply, simplifies the quantity of transferring devices for conveying the freezing boxes in the picking and managing system, enables each device to be more compact in arrangement, reduces the volume of the picking and managing system, and is more convenient to apply; in addition, the first cryopreservation box receiving and transferring device can be in butt joint with the X axis and the Y axis, so that the conveying requirements of the cryopreservation boxes in different directions can be met, and the application is more convenient.

Still further, the first cryopreservation box receiving and transferring device comprises a first mounting piece, a first lifting mechanism, a second mounting piece, a first horizontal sliding mechanism, a third mounting piece, a rotary shovel disc mechanism and a horizontal transferring mechanism; the first horizontal sliding mechanism, the rotary shovel disc mechanism and the horizontal transferring mechanism can change the corresponding height under the drive of the first lifting mechanism, the rotary shovel disc mechanism can move along the Y axis under the drive of the first horizontal sliding mechanism so as to be in butt joint with the pipe picking equipment to transfer the freezing box, the rotary shovel disc mechanism can rotate and stretch to move, so that the freezing box can be received and transferred along the X axis and the Y axis, and the horizontal transferring mechanism transfers the freezing box between the pipe picking equipment and the code scanning device; through the arrangement mode, the first horizontal sliding mechanism, the rotary shovel disc mechanism and the horizontal transfer mechanism share one lifting mechanism, so that the height of the first horizontal sliding mechanism, the rotary shovel disc mechanism and the horizontal transfer mechanism can be adjusted, the mechanisms are more compact, the volume of the first freezing storage box receiving and transferring device is reduced, and the cost is saved; second, the rotatory shovel dish mechanism realizes the receipt and the transfer of the cryopreservation box in two directions, and it uses more convenient.

Still further, the code scanning device and the second horizontal transfer mechanism are distributed at intervals, the second horizontal transfer mechanism can be driven by the first lifting mechanism to move to the same height as the code scanning device, the second horizontal transfer mechanism and the code scanning device are arranged in a right opposite way, and the second horizontal transfer mechanism is conveniently in butt joint with the code scanning device to transfer the frozen box; in addition, the position arrangement mode can reduce the volume between the picking pipes so as to improve the utilization rate of the space in the box body.

Still further, the second freezes to deposit box receiving transfer device includes first support piece, second horizontal sliding mechanism, second support piece and carries the box spare, carry box spare and second horizontal transfer mechanism to follow Y axle interval distribution, can make second horizontal transfer mechanism remove to the position with carrying box spare equiheight under first elevating system's drive, make second horizontal transfer mechanism just set up with carrying box spare, make things convenient for second horizontal transfer mechanism and carry box spare butt joint to transfer the freezes to deposit box, this position arrangement mode can reduce and select the volume between the pipe to improve the utilization ratio of box inner space.

Still further, choosing the pipe equipment includes third horizontal slip mechanism, frozen box fixed establishment and choosing the pipe device, third horizontal slip mechanism can drive frozen box fixed establishment and remove along the X axle, so that frozen box fixed establishment and rotatory shovel dish mechanism are received and are transferred frozen box, dock with horizontal transfer mechanism and receive and transfer frozen box, and transfer frozen box to sweep the sign indicating number on the sign indicating number device through horizontal transfer mechanism, and can dock with choosing the pipe device so that choosing the pipe device and choosing the pipe, such setting mode, with third horizontal slip mechanism through carrying frozen box fixed establishment along the Y axle, the position of frozen box fixed establishment is changed, the complexity of equipment is reduced, and can improve automatic transfer's beat, it sweeps sign indicating number and frozen box transfer's efficiency to choose the pipe, more convenient application.

Still further, the tube picking device further comprises a tube jacking device for jacking up the frozen tube upwards so that the tube picking device can smoothly carry out tube picking operation.

Still further, push bench includes third connecting piece, third elevating system and push bench, and the third connecting piece is connected with choosing the pipe clamp claw to make push bench and choosing pipe clamp claw sharing a elevating system and a moving mechanism on the Y axle, such setting mode has reduced push bench's complexity, is favorable to reduce cost and reduces the volume of choosing the pipe equipment, and in addition, choosing pipe clamp claw and push bench synchronous operation, can improve two complex precision, more convenient application.

Furthermore, the number of the storage rooms is two, the picking pipes are arranged between the two storage rooms, and one picking pipe is matched with the two storage rooms for use, so that the occupation ratio of the storage area in the box body can be improved, and the storage utilization rate is improved.

Drawings

Preferred embodiments of the present utility model are described below with reference to the accompanying drawings, in which:

FIG. 1 is a schematic perspective view of a biological sample storage library of the present utility model;

FIG. 2 is a schematic perspective view of a biological sample storage library according to the present utility model with a hidden portion of the housing;

FIG. 3 is a schematic diagram showing a second perspective view of the biological sample storage library according to the present utility model after the biological sample storage library has a hidden portion of the housing;

FIG. 4 is a schematic perspective view of a lifting and transferring apparatus according to the present utility model;

FIG. 5 is a schematic perspective view of a lifting mechanism of the present utility model;

FIG. 6 is a schematic perspective view of a transfer rack of the present utility model;

FIG. 7 is a schematic perspective view of a first horizontal transfer mechanism of the present utility model;

FIG. 8 is a front view of the present utility model with a transfer frame attached to a transfer frame guide;

FIG. 9 is a cross-sectional view taken along the direction A-A in FIG. 8;

FIG. 10 is a schematic diagram of the arrangement of the frozen box transfer device, the tube picking device and the code scanning device according to the utility model;

fig. 11 is a schematic perspective view of a first freezing storage box receiving and transferring device according to the present utility model;

fig. 12 is a schematic diagram showing a second perspective view of the first freezing storage box receiving and transferring device of the present utility model;

FIG. 13 is a front view of the first horizontal slide mechanism of the present utility model coupled to a rotating shovel disk mechanism;

FIG. 14 is a cross-sectional view taken in the direction B-B of FIG. 13;

FIG. 15 is a schematic layout view of the tube picking device and the code scanning device of the present utility model;

FIG. 16 is an enlarged schematic view of the structure at B in FIG. 15;

FIG. 17 is a schematic perspective view of a pipe picking device and a pipe jacking device according to the present utility model;

FIG. 18 is a schematic diagram showing a second perspective view of the pipe picking device and the pipe jacking device according to the present utility model;

fig. 19 is a schematic perspective view of a second freezing box receiving and transferring device of the present utility model;

fig. 20 is an enlarged schematic view of the structure at C in fig. 19.

List of reference numerals：

1. A case; 11. a storage room; 12. the tube picking room; 13. a sample receiving room; 101. a first access port; 102. a second inlet and outlet;

2. lifting the transfer device; 21. a first fixing member; 22. a lifting mechanism; 221. a second fixing member; 222. a first driving member; 223. a first screw rod; 224. a first screw rod sliding block; 225. a first guide assembly; 2251. a first linear guide rail; 2252. a first rail slider; 23. a transfer rack; 231. a frame body; 232. a storage location; 233. a first seal; 234. a second seal; 24. a first horizontal transfer mechanism; 241. a third fixing member; 242. a fourth fixing member; 243. a driving mechanism; 2431. a second driving member; 2432. a first drive gear; 2433. a first linear rack; 244. a second guide assembly; 2441. a second linear guide rail; 2442. a second rail block; 245. a first blade;

3. A cryopreservation box transfer device; 31. the first freezing storage box receives the transfer device; 311. a first mounting member; 312. a first lifting mechanism; 3121. a third driving member; 3122. a second screw rod; 3123. a second screw rod sliding block; 3124. a third guide assembly; 313. a second mounting member; 314. a first horizontal sliding mechanism; 3141. a fourth driving member; 3142. a second drive gear; 3143. a second linear rack; 3144. a first rail assembly; 31441. a first spacing rail; 31442. the first limiting slide block; 315. a third mount; 316. a rotary shovel disk mechanism; 3161. a fourth mount; 3162. a fifth mount; 3163. a rotation mechanism; 3164. a telescoping mechanism; 3165. a shovel disk member; 317. a second horizontal transfer mechanism; 3171. a sixth mounting member; 3172. a seventh mount; 3173. a seventh driving member; 3174. a third drive gear; 3175. a third linear rack; 3176. a second rail assembly; 31761. a second spacing rail; 31762. the second limit sliding block; 3177. a second blade; 32. the second freezing storage box receives the transfer device; 321. a first support; 322. a second horizontal sliding mechanism; 323. a second support; 324. a box carrying member;

4. a code scanning device; 41. a second support base; 42. the first code scanning camera; 43. the second code scanning camera; 44. a second cassette stage;

5. Tube picking equipment; 51. a third horizontal sliding mechanism; 511. an eighth driving member; 512. a third screw rod; 513. a third screw rod sliding block; 514. a fourth guide assembly; 5141. a second guide bar; 5142. a second guide ring; 52. a freezing storage box fixing mechanism; 521. a first support base; 522. a first cassette stage; 53. a tube picking device; 531. a first connector; 532. a second lifting mechanism; 533. a second connector; 534. a fourth horizontal sliding mechanism; 535. picking a pipe clamping jaw; 54. a pipe jacking device; 541. a third connecting member; 542. a third lifting mechanism; 543. a top pipe fitting;

6. a transfer frame guide; 61. a bottom plate; 62. a first support column; 621. a first guide chute; 63. a second support column; 631. the second guide chute; 64. a guide member; 641. a first guide block; 642. a second guide block;

7. and a detecting piece.

Detailed Description

Preferred embodiments of the present utility model are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present utility model, and are not intended to limit the scope of the present utility model.

It should be noted that, in the description of the present utility model, terms such as "upper," "lower," "inner," "outer," and the like indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, which are merely for convenience of description, and do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

Furthermore, it should be noted that, in the description of the present utility model, unless explicitly specified and limited otherwise, the terms "disposed," "mounted," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; may be directly connected or indirectly connected through other members. The specific meaning of the above terms in the present utility model can be understood by those skilled in the art according to the specific circumstances.

The existing automatic storage device based on the background technology is easy to damage samples due to tube picking operation in the process of storing and taking frozen storage tubes. According to the biological sample storage library, the tube picking and storing room is communicated, so that the temperatures of the tube picking and storing room are consistent, a sample is not inactivated in the tube picking operation process, and the sample inactivation risk is reduced; in addition, the sample receiving room is arranged above the picking pipe room, and the picking pipe room and the storage room are distributed along the horizontal direction, so that the distribution is reasonable, the structure is compact, the volume of the biological sample storage room is reduced, and the application is convenient.

Specifically, referring to fig. 1 to 3, the biological sample storage according to the present utility model includes a case 1, a lifting and transferring device 2, a code scanning device 4, a tube picking device 53, and a freezing box transferring device 3.

The inside of the box body 1 is provided with a storage room 11, a picking pipe room 12 and a sample receiving room 13, the picking pipe room 12 and the storage room 11 are communicated along the Y axis, the sample receiving room 13 is positioned above the picking pipe room 12, the sample receiving room 13 is communicated with the picking pipe room 12 through a first inlet and outlet 101, and the sample receiving room 13 is communicated with the external environment of the box body 1 through a second inlet and outlet 102. The tube picking room 12 is communicated with the storage room 11, the temperatures of the tube picking room 12 and the storage room 11 are consistent, a sample cannot be inactivated in the tube picking operation process, and the sample inactivation risk is reduced; the sample receiving room 13 is arranged above the picking pipe room 12, and the picking pipe room 12 and the storage room 11 are distributed along the horizontal direction, so that the distribution is reasonable, the structure is compact, the volume of the biological sample storage room is reduced, and the application is convenient.

The lifting and transferring device 2 is arranged in the sample receiving room 13, the lifting and transferring device 2 is arranged to transfer the freezing box between the picking pipe room 12 and the sample receiving room 13 through the first inlet and outlet 101, and the lifting and transferring device 2 is also arranged to transfer the freezing box between the sample receiving room 13 and the outside through the second inlet and outlet 102.

The code scanning device 4 is arranged in the pipe picking room 12 and is used for scanning the box code of the freezing box and the pipe code of the freezing pipe in the freezing box so as to manage the freezing box and the freezing pipe which are accessed.

The tube picking device 5 is arranged in the tube picking room 12 and is used for picking tubes so as to pick frozen tubes into other frozen boxes, so that the frozen tubes can be delivered out of the warehouse.

The frozen box transferring equipment 3 is arranged in the picking pipe room 12, and the frozen box transferring equipment 3 is arranged to transfer frozen boxes among the lifting transferring device 2, the picking pipe equipment 5, the code scanning device 4 and the storage room 11. The frozen box transferring equipment 3 transfers frozen boxes among the lifting transferring device 2, the tube picking equipment 5, the tube picking device 53 and the storage room 11, so that automatic access of the frozen boxes is realized, the duty ratio of the tube picking room 12 in the box body 1 can be reduced, and the storage utilization rate in the box body 1 is improved.

Preferably, referring to both fig. 3 and fig. 4, the lifting and transferring device 2 comprises a first fixing member 21, a lifting mechanism 22, a transferring frame 23 and a first horizontal transferring mechanism 24.

Wherein the first fixing member 21 is installed in the sample receiving room 13, the lifting mechanism 22 and the first horizontal transfer mechanism 24 are installed on the first fixing member 21 and located in the sample receiving room 13, the transfer frame 23 is connected with the lifting mechanism 22 and arranged through the first inlet and outlet 101, the transfer frame 23 can place frozen storage boxes in batches, the lifting mechanism 22 is arranged to drive the transfer frame 23 to move along the Z axis, so that the transfer frame 23 moves between a first transfer position and a second transfer position, the first transfer position is located in the sample receiving room 13, and the second transfer position is located in the picking pipe room 12; the first horizontal transfer mechanism 24 is arranged to be able to receive and transfer the cryopreservation cassette along the X-axis, wherein, in the case that the transfer frame 23 is in the first transfer position, the transfer frame 23 is arranged opposite to the second access opening 102, the first horizontal transfer mechanism 24 is able to receive the cryopreservation cassette on the transfer frame 23 and to transport the cryopreservation cassette to the external environment through the second access opening 102, and is able to receive the cryopreservation cassette in the external environment through the second access opening 102 and to place the cryopreservation cassette on the transfer frame 23.

Promote transfer device 2 and include hoist mechanism 22, transfer frame 23 and first horizontal transfer mechanism 24, hoist mechanism 22 is used for driving transfer frame 23 and removes along vertical direction to realize transferring the cryopreserved box in batches in vertical direction, more convenient the application, and can effectively improve the transport efficiency of cryopreserved box, first horizontal transfer mechanism 24 can be at the epaxial cryopreserved box that shifts of X, thereby can get the cryopreserved box on the storage position 232 and put, realize automatic getting and put the cryopreserved box, so that the automatic of realization cryopreserved box gets and put, facilitate the use. In addition, the transferring frame 23 and the second inlet and outlet 102 are opposite to each other, when the frozen storage boxes are stored and taken out in batches, the frozen storage boxes can be placed on the transferring frame 23 in batches by manpower or taken down on the transferring frame 23 in batches, so that the stay time of the frozen storage boxes in the sample receiving room 13 can be shortened, and the activity of the samples is ensured.

Preferably, with continued reference to fig. 5, the lifting mechanism 22 includes a second fixing member 221, a first driving member 222, a first screw 223, and a first screw slider 224.

Wherein the first screw slider 224 is connected with the transport frame 23; the second fixing member 221 is mounted on the first fixing member 21, the first screw rod 223 is rotatably mounted on the second fixing member 221 and extends along the Z axis, the first screw rod slider 224 is sleeved on the first screw rod 223 and is in threaded connection with the first screw rod 223, and the first driving member 222 is connected with the first screw rod 223 and can drive the first screw rod 223 to rotate, so that the first screw rod slider 224 and the transport frame 23 are driven to move along the Z axis relative to the second fixing member 221.

The lifting mechanism 22 is provided with a second fixing piece 221, a first driving piece 222, a first screw 223 and a first screw slider 224, and has a simple structure and is convenient to assemble and use.

Although in the above preferred embodiment, the lifting mechanism 22 adopts a structure that the driving member drives the screw rod to rotate so as to drive the sliding block to move, this should not limit the scope of the present utility model, and in practical application, those skilled in the art may also set the lifting mechanism 22 in other structures. For example, the lifting mechanism 22 may be configured such that the driving member drives the gear to rotate and engage the rack to move relative to the rack. Such modifications and changes in the specific structure of the lifting mechanism 22 do not depart from the basic principles of the present utility model and are intended to be within the scope of the present utility model. Of course, the lifting mechanism 22 is preferably configured in a structure that the driving member drives the screw rod to rotate so as to drive the sliding block to move, and compared with a structure that the driving member drives the sliding block through a gear rack, the lifting mechanism is better in stability.

Preferably, with continued reference to fig. 5, the lifting mechanism 22 further includes a first guide assembly 225, the first guide assembly 225 being located between the second fixing member 221 and the first screw slider 224, the first guide assembly 225 being capable of guiding the first screw slider 224 during movement of the first screw slider 224 relative to the second fixing member 221 so as to enable the first screw slider 224.

Through setting up first direction subassembly 225, can lead first lead screw slider 224, make first lead screw slider 224 make rectilinear movement for second mounting 221, can effectively avoid first lead screw slider 224 to take place to rotate, better control promotes the precision, more convenient application.

Preferably, with continued reference to fig. 5, the first guide assembly 225 includes a first linear guide 2251 and a first guide rail slider 2252, the first linear guide 2251 being mounted on the second mount 221 and extending along the Z-axis, the first guide rail slider 2252 being coupled to the transfer frame 23, the first guide rail slider 2252 being slidably coupled to the first linear guide 2251 and being movable along the first linear guide 2251.

The first guide assembly 225 is provided as a first linear guide 2251 and a second guide rail slider 2442, which has a simple structure, is convenient to assemble and use, and has a small volume after assembly.

Although in the above preferred embodiment, the first guide assembly 225 is provided as the first linear guide 2251 and the first guide slider 2252, this should not limit the scope of the present utility model, and in practical applications, those skilled in the art may also provide the first guide assembly 225 with other structures. For example, the first guide assembly 225 may be configured as a first guide bar vertically installed on the second fixing member 221 and a first guide ring coupled with the slider, and sleeved on the first guide bar and capable of sliding along the first guide bar. Such modifications and changes in the specific structure of the first guide assembly 225 are not intended to depart from the basic principles of the present utility model and are intended to be within the scope of the present utility model. Of course, the first guide assembly 225 is preferably provided as a first linear guide 2251 and a first guide slider 2252, which has a simple structure and small volume after assembly, and is convenient for application.

Preferably, the number of the first guide members 225 is two, and the two first guide members 225 are respectively located at both sides of the first screw 223.

The first guiding components 225 are arranged at two sides of the first screw rod 223, so that the sliding blocks can be better guided, and the sliding blocks are prevented from rotating, so that the transportation frame 23 is prevented from rotating in the transportation process.

Preferably, referring next to FIG. 7, first horizontal transfer mechanism 24 includes a third mount 241, a fourth mount 242, a drive mechanism 243, a second guide assembly 244, and a first blade 245.

The third fixing piece 241 is mounted on the first fixing piece 21, the fourth fixing piece 242 is connected with the third fixing piece 241 through the second guiding component 244, the fourth fixing piece 242 extends along the X axis, the first end of the fourth fixing piece 242 extends towards the transportation frame 23, the first shovel 245 is mounted at the first end of the fourth fixing piece 242, the driving mechanism 243 is connected with the fourth fixing piece 242 and can drive the fourth fixing piece 242 and the first shovel 245 to move along the X axis relative to the third fixing piece 241, and the second guiding component 244 can guide the fourth fixing piece 242 in the process that the fourth fixing piece 242 moves relative to the third fixing piece 241, so that the fourth fixing piece 242 moves linearly.

The first horizontal transfer mechanism 24 is arranged to be the third fixing piece 241, the fourth fixing piece 242, the driving mechanism 243, the second guiding component 244 and the first shovel plate 245, and the driving mechanism 243 drives the fourth fixing piece 242 to stretch and retract towards the transfer frame 23 relative to the third fixing piece 241, so that the first shovel plate 245 can be in butt joint with a freezing box on the storage position 232, the transfer frame 23 is driven to vertically move by the cooperation of the lifting mechanism 22, the freezing box can be transferred to the first shovel plate 245 or the freezing box on the first shovel plate 245 is placed on the storage position 232, and the freezing box can be automatically taken and placed, so that the freezing box is more convenient to use. In addition, the first horizontal transfer mechanism 24 is simple in structure and convenient to assemble and use.

Preferably, with continued reference to FIG. 7, the drive mechanism 243 includes a second drive 2431 (e.g., a servo motor or stepper motor), a first drive gear 2432, and a first linear rack 2433.

The second driving member 2431 is mounted on the third fixing member 241, the first linear rack 2433 is mounted on the fourth fixing member 242 and extends along the X axis, the second driving member 2431 is connected with the first driving gear 2432 and can drive the first driving gear 2432 to rotate, the first linear rack 2433 is meshed with the first driving gear 2432, and the first driving gear 2432 can drive the first linear rack 2433 and the fourth fixing member 242 to move when rotating.

The driving mechanism 243 is configured as a second driving member 2431, a first driving gear 2432 and a first linear rack 2433, and has a simple structure and is convenient to assemble and use.

Although the driving mechanism 243 is provided as the second driver 2431, the first driving gear 2432, and the first linear rack 2433 in the above-described embodiment, this should not limit the scope of the present utility model. In practical applications, those skilled in the art may also set the driving mechanism 243 in other configurations. For example, the driving mechanism 243 may be configured as a mechanism that a motor drives a screw to move a screw slider. Such modifications and changes in the specific structure of the driving mechanism 243 do not depart from the basic principle of the present utility model and are intended to be within the scope of the present utility model. Of course, the above-mentioned configuration of providing the driving mechanism 243 as the second driver 2431, the first driving gear 2432, and the first linear rack 2433 is preferable, and the structure is simple and the volume after assembly is smaller.

Preferably, with continued reference to fig. 7, the second guide assembly 244 includes a second linear guide 2441 and a second guide slider 2442, the second linear guide 2441 is mounted on the fourth fixing member 242 and extends along the X-axis, the second guide slider 2442 is mounted on the third fixing member 241, and the second guide slider 2442 is slidably connected to the second linear guide 2441 and is capable of moving along the second linear guide 2441.

The second guide assembly 244 is arranged to be a second linear guide 2441 and a second guide slide 2442, and has simple structure and good guide effect.

In other embodiments, the second guide assembly 244 may be configured as a second guide rod mounted on the fourth fixing member 242 and extending in the longitudinal direction of the fourth fixing member 242, and a second guide ring mounted on the third fixing member 241 and sleeved on the second guide rod and capable of sliding along the second guide rod.

It should be noted that, the specific structure of the second guiding assembly 244 is not limited by the present utility model, and in practical applications, a person skilled in the art may set the specific structure of the second guiding assembly 244 according to actual needs. The specific implementation of the second guide assembly 244 in the above embodiment is not intended to limit the scope of the present utility model.

Preferably, referring to fig. 6, the transferring rack 23 includes a rack body 231, a plurality of storage positions 232 are disposed in the rack body 231, the plurality of storage positions 232 are arranged in an array along a length direction and a height direction of the rack body 231 to form a plurality of columns and layers, each storage position 232 has a first opening and a second opening for taking and placing the freezing storage box, and the first opening and the second opening are disposed opposite to each other.

The plurality of storage positions 232 distributed in a multi-row and multi-layer matrix form are arranged in the frame 231, so that the plurality of storage positions 232 are distributed in an array form, the positioning is convenient, and the size is small.

Preferably, in the present embodiment, the frame 231 includes a first vertical plate, a second vertical plate, a first horizontal plate, a second horizontal plate, a plurality of partitions, and a plurality of carriers.

The first vertical board and the horizontal interval of second vertical board set up, and its big face is relative, the roof of the first vertical board and the roof of the vertical board of second are connected through first horizontal plate, the diapire of the vertical board of first vertical board and the diapire of the vertical board of second are connected through the second horizontal plate, the baffle is located between the vertical board of first vertical board and the vertical board of second, and roof and the diapire of baffle are connected with first horizontal plate and second horizontal plate respectively, a plurality of baffles divide into a plurality of holding chamber with the storage interval that first vertical board, the vertical board of second, first horizontal plate and second horizontal plate enclose into equally, and hold the opposite both sides in chamber and have the opening, every holds the intracavity and be provided with a plurality of bearings along vertical direction interval, the top surface of bearing forms storage position 232.

Although the frame 231 is provided as the first vertical plate, the second vertical plate, the first horizontal plate, the second horizontal plate, the plurality of partitions, and the plurality of carriers in the above embodiment, this should not limit the scope of the present utility model, and in practical applications, those skilled in the art may provide other structures for the frame 231. For example, the frame 231 may be configured as a frame with a square shape and a plurality of carrying objects located in the frame, the frame is divided into a plurality of holding cavities distributed horizontally at intervals by partition members, opposite sides of the holding cavities are provided with openings, each holding cavity is internally provided with a plurality of carrying objects distributed at intervals along a vertical direction, and a top surface of each carrying object forms a storage position 232. Such modifications and changes in the specific structure of the frame 231 do not depart from the basic principle of the present utility model, and should be construed as being limited to the scope of the present utility model.

Preferably, with continued reference to fig. 6, the top and bottom of the transfer frame 23 are provided with a first seal 233 and a second seal 234, respectively, and the lifting mechanism 22 is connected to the first seal 233, the first seal 233 sealing the first access port 101 in the case where the transfer frame 23 is in the second transfer position, and the second seal 234 sealing the first access port 101 in the case where the transfer frame 23 is in the first transfer position.

The first sealing piece 233 and the second sealing piece 234 are respectively arranged at the top and the bottom of the transferring frame 23, so that the first inlet and outlet 101 can be sealed, the communication between the sample receiving room 13 and the picking pipe room 12 is avoided, cold air in the picking pipe room 12 is effectively prevented from entering the sample receiving room 13, the environment in the picking pipe room 12 is kept stable, and the cold energy consumption is reduced.

In practical applications, the first seal 233 and the second seal 234 may seal the first port 101.

Illustratively, the first sealing member 233 includes a first insulating block and a first sealing plate, the first insulating block matches the shape of the first inlet/outlet 101, the first sealing member 233 is located in the first inlet/outlet 101 when sealing the first inlet/outlet 101, and the first sealing plate abuts against the top surface of the partition where the first inlet/outlet 101 is located, so as to seal the gap between the first insulating block and the first inlet/outlet 101.

Illustratively, the second sealing member 234 includes a second insulating block and a second sealing plate, the second insulating block is matched with the shape of the first inlet and outlet 101, the second sealing member 234 is positioned in the first inlet and outlet 101 when sealing the first inlet and outlet 101, and the second sealing plate abuts against the bottom surface of the partition where the first inlet and outlet 101 is positioned, so as to seal the gap between the second insulating block and the first inlet and outlet 101.

Preferably, referring next to fig. 3, the biological sample storage library of the present utility model further comprises a transfer rack guide 6, wherein the transfer rack guide 6 is positioned in the picking chamber 12, and the transfer rack guide 6 is connected to the transfer rack 23 and can guide the transfer rack 23 during the up-and-down movement of the transfer rack 23 so as to make the transfer rack 23 move linearly.

The transfer frame guide device 6 is arranged in the picking pipe room 12, and guides the transfer frame 23 in the process of moving the transfer frame 23 up and down so as to ensure that the transfer frame 23 moves linearly, ensure that the transfer frame 23 keeps stable and does not shake, and be beneficial to improving the transfer safety of the freezing storage box.

Preferably, referring next to fig. 8 and 9, the transfer frame guide 6 includes a base plate 61, a first support column 62, a second support column 63, and a guide 64.

The first support column 62 and the second support column 63 are vertically installed on the bottom plate 61, the first support column 62 and the second support column 63 are respectively located at two sides of the transportation frame 23, the first support column 62 and the second support column 63 are respectively provided with a first guide chute 621 and a second guide chute 631, the first guide chute 621 and the second guide chute 631 are respectively arranged in an extending mode along the vertical direction, the guide piece 64 is connected with the bottom of the transportation frame 23, the guide piece 64 is provided with a first guide block 641 and a second guide block 642, the first guide block 641 is located in the first guide chute 621 and can slide in the first guide chute 621 along the length direction of the first guide chute 621, and the second guide block 642 is located in the second guide chute 631 and can slide in the second guide chute 631 along the length direction of the second guide chute 631.

The transportation frame guiding device 6 is arranged to be a bottom plate 61, a first supporting column 62, a second supporting column 63 and a guiding piece 64, and is simple in structure, capable of guiding two sides of the transportation frame 23 simultaneously, better in guiding effect and capable of guaranteeing that the transportation frame 23 is kept stable in the moving process.

Preferably, with continued reference to fig. 8, the biological sample storage library of the present utility model further comprises a detecting member 7, wherein the detecting member 7 is mounted on top of the transport frame guiding device 6, the detecting member 7 is horizontally disposed towards the transport frame 23, and the detecting member 7 can detect whether a freezing box exists at the storage position 232 with the same height as the detecting member 7.

By arranging the detecting piece 7, whether the freezing storage box exists in the storage position 232 can be detected, and the application is more convenient. The detecting piece 7 may be a distance sensor, and when the detecting piece 7 faces the storage position 232 and the freezing box is placed on the storage position 232, the freezing box can reflect light emitted by the distance sensor back, so that the distance sensor can detect that articles exist.

Preferably, as shown in fig. 8, the number of the detecting elements 7 is plural, the detecting elements 7 are distributed at intervals along the length direction of the transferring rack 23, and each row of the storage positions 232 corresponds to one detecting element 7.

The detection pieces 7 are arranged in a plurality, and each row of storage positions 232 is correspondingly provided with one detection piece 7, so that each row of storage positions 232 of the transfer rack 23 can be effectively detected, and the application is more convenient.

Preferably, referring next to fig. 10, the cryopreservation cassette transfer apparatus 3 includes a first cryopreservation cassette receiving and transferring device 31 and a second cryopreservation cassette receiving and transferring device 32, the first cryopreservation cassette receiving and transferring device 31 is configured to be capable of receiving and transferring the cryopreservation cassettes along the X axis and the Y axis, and the first cryopreservation cassette receiving and transferring device 31 is capable of interfacing with the lifting and transferring device 2, the tube picking apparatus 5, the code scanning device 4, and the second cryopreservation cassette receiving and transferring device 32, respectively, to receive and transfer the cryopreservation cassettes; the second freezing box receiving and transferring device 32 is provided to be able to transfer the freezing box between the first freezing box receiving and transferring device 31 and the storage room 11.

The first freezing box receiving and transferring device 31 can receive and transfer freezing boxes along the Y axis and the X axis, so that the first freezing box receiving and transferring device 31 can be used for receiving and transferring the freezing boxes in a butt joint mode in two perpendicular directions, the application is more convenient, one transferring device can realize the transportation in two directions, the quantity of transferring devices for partially transporting the freezing boxes is reduced, the size of a picking pipe system is reduced, and the assembly and the use are convenient; in addition, the first freezing box receiving and transferring device 31 can be in butt joint with the tube picking device 5 and the code scanning device 4 so as to realize code scanning and tube picking operation; the second freezing box receiving and transferring device 32 is used for transferring the freezing box between the picking pipe 12 and the storage room 11 so as to realize automatic access of the freezing box and the freezing pipe in cooperation with the first freezing box receiving and transferring device 31.

Preferably, with continued reference to fig. 11 and 12, the first cryopreservation cassette receiving and transporting apparatus 31 includes a first mount 311 and a first lifting mechanism 312, a second mount 313, a first horizontal sliding mechanism 314, a third mount 315, a rotating shovel disk mechanism 316, and a second horizontal transfer mechanism 317 mounted on the first mount 311.

The first mounting piece 311 is connected with the box 1, the second mounting piece 313 is connected with the first elevating system 312, the first horizontal sliding mechanism 314 and the second horizontal transferring mechanism 317 are mounted on the second mounting piece 313, the first horizontal sliding mechanism 314 and the second horizontal transferring mechanism 317 are distributed at intervals along the X axis, the third mounting piece 315 is connected with the first horizontal sliding mechanism 314, and the rotary shovel disk mechanism 316 is mounted on the third mounting piece 315. Through such setting, the rational distribution space makes cooperation linkage between each mechanism to do not influence each other, help reducing the volume of whole device.

The first lifting mechanism 312 is configured to move the second mounting member 313, the first horizontal sliding mechanism 314, the second horizontal transfer mechanism 317, the third mounting member 315, and the rotating blade mechanism 316 along the Z-axis. The first horizontal sliding mechanism 314, the second horizontal transferring mechanism 317 and the rotary shovel disk mechanism 316 share one lifting mechanism to adjust the height thereof, so that the cost is effectively saved, and the assembly and the use are convenient.

The first horizontal sliding mechanism 314 is configured to drive the third mounting member 315 and the rotary shovel disk mechanism 316 to move along the Y axis, so that the rotary shovel disk mechanism 316 can dock with the pipe picking device 5 to transfer the freezing box. The first horizontal sliding mechanism 314 can drive the rotary shovel disk mechanism 316 to move along the Y axis, so that the position of the rotary shovel disk mechanism 316 on the Y axis can be changed, and the rotary shovel disk mechanism can be better abutted with the pipe picking device 5 to transfer the freezing box, and is more convenient to use.

The rotary blade mechanism 316 is configured to rotate circumferentially about a vertical axis and to move telescopically along its length to receive and transfer a cryopreservation cassette. The rotary shovel disk mechanism 316 can rotate and move in a telescopic manner, and can be abutted against different directions, so that the freezing box can be received and transferred in different directions, the convenience of use is improved, and various requirements can be met.

The second horizontal transfer mechanism 317 is provided so as to be able to receive and transfer the cryopreservation cassette along the Y axis, and to be able to transfer the cryopreservation cassette between the picking tube apparatus 5, the code scanning device 4, and the second cryopreservation cassette receiving and transferring device 32. The second horizontal transfer mechanism 317 can transfer the cryopreserved box between the tube picking device 5, the code scanning device 4 and the second cryopreserved box receiving and transferring device 32, so that the code scanning is conveniently performed on the cryopreserved box before and after tube picking, and the management of the cryopreserved box and the cryopreserved tube is facilitated.

By means of the arrangement mode, the first freezing storage box receiving and transferring device 31 is more compact in structure, the size is reduced, and the cost is saved.

Preferably, with continued reference to FIG. 11, the first lift mechanism 312 includes a third drive member 3121 (e.g., a servo motor or stepper motor), a second lead screw 3122, a second lead screw slider 3123, and a third guide assembly 3124.

Wherein, the third driving member 3121 and the second screw 3122 are both installed on the first installation member 311, the second screw 3122 extends along the vertical direction, the second installation member 313 is connected with the second screw slider 3123, the second screw slider 3123 is sleeved on the second screw 3122 and is in threaded connection with the second screw 3122, the third driving member 3121 is connected with the second screw 3122 and can drive the second screw 3122 to rotate, thereby driving the second screw slider 3123 and the second installation member 313 to move along the Z axis.

The third guiding assembly 3124 is located between the second screw slider 3123 and the first mounting member 311, and the third guiding assembly 3124 can guide the second screw slider 3123 during the movement of the second screw slider 3123 along the Z axis, so as to make the second screw slider 3123 move linearly and avoid the second screw slider 3123 from rotating.

In operation, third drive member 3121 drives second screw 3122 to rotate, guided by third guide assembly 3124, such that second screw slider 3123 moves along the second mount along the Z-axis, thereby enabling adjustment of the heights of first horizontal sliding mechanism 314, rotary shovel disk mechanism 316, and horizontal transfer mechanism. The whole structure is simple, the assembly and the use are convenient, and the first lifting mechanism 312 is arranged in a driving mode of a driving piece matched with the screw rod and the screw rod sliding block, and compared with a driving mode of a driving piece matched with a gear and a rack, the stability is better.

Although in the above embodiment, the first lifting mechanism 312 is set to a driving form in which the third driving member 3121 drives the second screw 3122 to rotate so as to drive the second screw slider 3123 to move, this should not limit the scope of the present utility model, and in practical applications, those skilled in the art may set the first lifting mechanism 312 to other driving forms. For example: the first elevating mechanism 312 may be configured in a driving form in which the third driving member 3121 drives the rotation of the gear, thereby driving the rack to move. Such modifications and changes in the specific structure of the first elevating mechanism 312 do not depart from the basic principle of the present utility model and are intended to be within the scope of the present utility model. Of course, the above driving mode of setting the first lifting mechanism 312 to the driving mode that the third driving member 3121 drives the second screw 3122 to rotate so as to drive the second screw slider 3123 to move is preferred, and the lifting movement process is more stable and the driving force is stronger.

Preferably, the third guide assembly 3124 includes a first guide rod mounted on the first mounting member 311 and extending along the Z-axis, and a first guide ring sleeved on the first guide rod, the first guide ring being movable along the first guide rod and being connected to the second screw slider 3123.

In other embodiments, the third guiding assembly 3124 may also include a guiding sliding rail and a guiding sliding block matched with the guiding sliding rail, the guiding sliding rail is installed on the first installation piece 311 and is arranged along the Z-axis in a diffraction manner, the guiding sliding block is connected with the second screw sliding block 3123, and the guiding sliding block can slide along the guiding sliding rail.

It should be noted that, the specific structure of the third guide assembly 3124 is not limited in any way, and in practical applications, a person skilled in the art may set the specific structure of the third guide assembly 3124 according to practical needs, as long as the third guide assembly 3124 is capable of guiding the second screw slider 3123 so as to make the second screw slider 3123 move linearly. The specific implementation of the third guide assembly 3124 described above should not be construed as limiting the scope of the present utility model. Of course, the third guide assembly 3124 is preferably configured in a structure of the first guide bar and the first guide ring, and can be assembled with the second screw 3122 at the same time, so that the structural stability thereof is better.

Preferably, the number of the third guide members 3124 is two, and is located at both sides of the second screw 3122, respectively.

The third guide assemblies 3124 are arranged at two sides of the second screw 3122, so that the guide effect is better, the limit effect is better, and the second screw slider 3123 can be effectively prevented from rotating relative to the first mounting piece 311.

Preferably, referring next to fig. 13 and 14, the first horizontal sliding mechanism 314 includes a fourth driver 3141 (e.g., a servo motor or a stepper motor), a second drive gear 3142, a second linear rack 3143, and a first rail assembly 3144.

The second linear rack 3143 is mounted on the second mounting member 313 and extends along the Y axis, the fourth driving member 3141 is mounted on the third mounting member 315, the fourth driving member 3141 is connected with the second driving gear 3142 and can drive the second driving gear 3142 to rotate, the second driving gear 3142 is in meshed connection with the second linear rack 3143, and the second driving gear 3142 can drive the third mounting member 315 and the fourth driving member 3141 to move along the Y axis relative to the second linear rack 3143 when rotating.

The first rail assembly 3144 is located between the second mount 313 and the third mount 315, and the first rail assembly 3144 is capable of guiding the third mount 315 during movement of the third mount 315 relative to the second mount 313 to move the third mount 315 linearly and to maintain the second drive gear 3142 in engagement with the second linear rack 3143.

In actual operation, the fourth driver 3141 drives the second driving gear 3142 to rotate, so that the second driving gear 3142 and the second linear rack 3143 move relatively, and the third mount 315, the fourth driver 3141, the second driving gear 3142, and the rotary shovel mechanism 316 can move along the Y axis. The first rail assembly 3144 guides the third mounting member 315 to move the third mounting member 315 in a straight line so that it remains stable during the movement.

Preferably, with continued reference to fig. 14, first rail assembly 3144 includes a first spacing rail 31441 and a first spacing slider 31442, first spacing rail 31441 is mounted on second mounting member 313 and extends along the Y-axis, first spacing slider 31442 is slidably coupled to first spacing rail 31441 and is movable along the length of first spacing rail 31441, and first spacing slider 31442 is coupled to third mounting member 315.

The first limit rail 31441 is provided with a first limit structure (for example, a limit chute or a limit protrusion), and the first limit slider 31442 is provided with a second limit structure (for example, a limit protrusion matched with the limit chute or a limit chute matched with the limit protrusion), and the first limit structure and the second limit structure are matched to limit the movement of the first limit slider 31442 relative to the first limit rail 31441 in the width direction and the thickness direction of the first limit rail 31441. When the second mounting member 313 and the third mounting member 315 are vertically disposed, the second mounting member 313 and the third mounting member 315 can be kept relatively stable.

The first guide rail assembly 3144 is configured as the first limit guide rail 31441 and the first limit slider 31442, and has a simple structure, convenient assembly and use, good guiding and limit effects, and normal operation of the first horizontal sliding mechanism 314.

Although in the above embodiment, the first rail assembly 3144 is provided as the first limit rail 31441 and the first limit slider 31442, this should not limit the scope of the present utility model, and in practical applications, those skilled in the art may also provide the first rail assembly 3144 with other structures. For example, the first rail assembly 3144 may be configured as a guide bar mounted on the second mount 313 and extending along the Y axis, and a guide slip ring provided to be sleeved on the guide bar, the guide slip ring being connected to the third mount 315 and capable of sliding along the guide bar. Such modifications and changes in the specific structure of first rail assembly 3144 may be made without departing from the principles of the present utility model and are intended to be within the scope of the present utility model.

Preferably, with continued reference to fig. 13 and 14, rotary blade mechanism 316 includes a fourth mount 3161 and fifth mount 3162, rotary mechanism 3163, telescoping mechanism 3164, and blade 3165 mounted on fourth mount 3161.

Wherein, fourth mount 3161 is mounted on third mount 315, fifth mount 3162 is connected with fourth mount 3161 through rotary mechanism 3163, telescopic mechanism 3164 and shovel disk 3165 are mounted on fifth mount 3162, rotary mechanism 3163 is arranged so as to be capable of driving fifth mount 3162, telescopic mechanism 3164 and shovel disk 3165 to rotate around the vertical axis, and telescopic mechanism 3164 is arranged so as to be capable of driving shovel disk 3165 to extend and retract in the length direction of fifth mount 3162.

In actual operation, the rotating mechanism 3163 drives the fifth mounting member 3162, the telescopic mechanism 3164 and the shovel disk member 3165 to rotate, so that the butt joint direction of the shovel disk member 3165 is changed, the telescopic mechanism 3164 drives the shovel disk member 3165 to stretch and retract, and the first lifting mechanism 312 is matched to drive the rotating shovel disk mechanism 316 to lift, so that the freezing box can be received and transferred in a butt joint mode. The whole structure is compact, the volume is small and the assembly and the use are convenient.

Preferably, the rotation mechanism 3163 includes a fifth driver (e.g., a servo motor or a stepper motor), a driving gear, and a driven gear.

The driven gear is fixedly connected with the fifth mounting member 3162 and is rotationally connected with the fourth mounting member 3161 through a bearing, the fifth driving member is mounted on the fourth mounting member 3161 and is connected with the driving gear and can drive the driving gear to rotate, the driving gear is meshed with the driven gear and is connected with the driven gear, and the driven gear and the fifth mounting member 3162 can be driven to rotate when the driving gear rotates.

The rotation mechanism 3163 is provided as a fifth driving member, a driving gear and a driven gear, and drives the fifth mounting member 3162 to rotate through gear transmission, so that the rotation mechanism is reliable in driving, simple in structure and convenient to assemble and use.

Preferably, telescoping mechanism 3164 includes a sixth drive (e.g., a servo motor or stepper motor), a drive assembly (e.g., a rack and pinion drive assembly or a link gear drive assembly), a linear guide, and a guide slide.

The sixth driving member is mounted on the fifth mounting member 3162, the sixth driving member is connected with the guide rail sliding block through the transmission assembly, the linear guide rail is mounted on the fifth mounting member 3162 and extends along the length direction of the fifth mounting member 3162, the guide rail sliding block is slidably connected with the linear guide rail and can slide along the length direction of the linear guide rail, the shovel disk member 3165 is mounted on the guide rail sliding block, the sixth driving member is connected with the transmission assembly and can drive the guide rail sliding block and the shovel disk member 3165 to slide along the length direction of the linear guide rail through the transmission assembly, and therefore the shovel disk member 3165 stretches and contracts.

The telescopic mechanism 3164 is arranged as the sixth driving piece, the transmission assembly, the linear guide rail and the guide rail sliding block, the structure is simple, the assembly and the use are convenient, and the guide limiting position of the linear guide rail and the guide rail sliding block can enable the shovel disk 3165 to linearly move in a telescopic manner, so that the control is more convenient.

Preferably, referring to fig. 10, the code scanning device 4 and the second horizontal transferring mechanism 317 are spaced apart along the Y-axis, and the first lifting mechanism 312 drives the second horizontal transferring mechanism 317 to move to the same height as the code scanning device 4, and the second horizontal transferring mechanism 317 is opposite to the code scanning device 4.

The code scanning device 4 is arranged on one side of the second horizontal transfer mechanism 317, so that the two are in butt joint, the application is convenient, and the space can be saved.

Preferably, referring to fig. 16, the code scanning device 4 includes a second support seat 41, a first code scanning camera 42, a second code scanning camera 43 and a second box loading platform 44, which are disposed on the second support seat 41, and the second box loading platform 44 is capable of placing a frozen box; the first code scanning camera 42 is horizontally arranged along the Y axis, and can scan the code of the freezing storage box on the second box carrying table 44, the second code scanning camera 43 is vertically arranged along the Z axis, and can scan the code of the freezing storage tube in the freezing storage box on the second box carrying table 44.

The code scanning device 4 is arranged to be a second supporting seat 41, a first code scanning camera 42, a second code scanning camera 43 and a second box carrying table 44, and is simple in structure and convenient to assemble and use.

Preferably, referring next to fig. 11 and 12, second horizontal transfer mechanism 317 includes a sixth mount 3171, a seventh mount 3172, a seventh drive 3173 (e.g., a servo motor or stepper motor), a third drive gear 3174, a third linear rack 3175, a second rail assembly 3176, and a second blade 3177.

The sixth mounting member 3171 is connected to the second mounting member 313, the seventh mounting member 3172 is connected to the sixth mounting member 3171 through the second rail assembly 3176, the seventh driving member 3173 is mounted on the sixth mounting member 3171, the third linear rack 3175 is mounted on the seventh mounting member 3172 and extends along the Y axis, the second shovel plate 3177 is mounted at an end portion of the seventh mounting member 3172, which is close to the code scanning device 4, in the Y axis direction, the seventh driving member 3173 is connected to the third driving gear 3174 and is capable of driving the third driving gear 3174 to rotate, the third driving gear 3174 is in meshed connection with the third linear rack 3175, and the third driving gear 3174 can drive the third linear rack 3175, the seventh mounting member 3172 and the second shovel plate 3177 to move along the Y axis relative to the sixth mounting member 3171 when rotating.

The second rail assembly 3176 can guide the seventh mount 3172 in the course of moving the seventh mount 3172 with respect to the sixth mount 3171 to linearly move the seventh mount 3172, and can maintain the third drive gear 3174 in an engaged state with the third linear rack 3175.

In actual operation, seventh driving member 3173 drives third driving gear 3174 to rotate, and makes third driving gear 3174 and third linear rack 3175 relatively move, so that under the guiding and limiting effects of second guide rail assembly 3176, seventh mounting member 3172, third linear rack 3175 and second shovel plate 3177 move along the Y axis relative to sixth mounting member 3171, and the structure is simple, and assembly and use are convenient.

Preferably, with continued reference to fig. 12, second rail assembly 3176 includes a second spacing rail 31761 and a second spacing slider 31762, second spacing rail 31761 is mounted on sixth mounting member 3171 and extends along the Y-axis, second spacing slider 31762 is slidably coupled to second spacing rail 31761 and movable along the length of second spacing rail 31761, and second spacing slider 31762 is coupled to seventh mounting member 3172.

The second limiting rail 31761 is provided with a third limiting structure (for example, a limiting chute or a limiting protrusion), the second limiting slider 31762 is provided with a fourth limiting structure (for example, a limiting protrusion matched with the limiting chute or a limiting chute matched with the limiting protrusion), and the movement of the second limiting slider 31762 relative to the second limiting rail 31761 in the width direction and the thickness direction of the second limiting rail 31761 can be limited by the cooperation of the third limiting structure and the fourth limiting structure.

The second guide rail assembly 3176 is arranged to be a second limit guide rail 31761 and a second limit sliding block 31762, and is simple in structure, convenient to assemble and use, and good in guiding and limit effects.

Although in the above embodiment, the second rail assembly 3176 is provided as the second limit rail 31761 and the second limit slider 31762, this should not limit the scope of the present utility model, and in practical applications, those skilled in the art may also provide the second rail assembly 3176 in other structures. For example, the second rail assembly 3176 may be configured as a guide bar mounted on the sixth mounting member 3171 and extending along the Y axis, and a guide slip ring provided to be sleeved on the guide bar, the guide slip ring being connected to the seventh mounting member 3172 and being slidable along the guide bar. Such modifications and changes in the specific structure of second rail assembly 3176 do not depart from the basic principles of the present utility model and are intended to be within the scope of the present utility model.

Preferably, referring to fig. 19 and 20, the second freezing storage box receiving and transferring device 32 includes a first support 321, and a second horizontal sliding mechanism 322, a second support 323 and a box carrier 324 mounted on the first support 321.

Wherein the second supporting member 323 is mounted on the second horizontal sliding mechanism 322, and the box loading member 324 is mounted on the second supporting member 323, and the box loading member 324 is capable of carrying the freezing box; the second horizontal sliding mechanism 322 is configured to drive the second supporting member 323 and the box carrying member 324 to move along the Y axis, so as to transfer the frozen box between the picking tube 12 and the storage room 11, the box carrying member 324 and the second horizontal transferring mechanism 317 are distributed along the Y axis at intervals, and the first lifting mechanism 312 drives the second horizontal transferring mechanism 317 to move to the same height as the box carrying member 324, where the second horizontal transferring mechanism 317 and the box carrying member 324 are opposite to each other.

The arrangement mode is simple in structure and convenient to assemble and use.

Preferably, referring to fig. 10, the box loading members 324 and the horizontal transferring mechanisms are spaced apart along the Y-axis, and the first lifting mechanism 312 drives the second horizontal transferring mechanism 317 to move to the same height as the box loading members 324, the second horizontal transferring mechanism 317 is opposite to the box loading members 324, so that the second horizontal transferring mechanism 317 is in butt joint with the box loading members 324, and the frozen box is placed on the box loading members 324 and the frozen box on the box loading members 324 is removed.

The box loading member 324 is arranged at one side of the second horizontal transferring mechanism 317, so that the two parts are in butt joint for transferring the freezing box, thereby being convenient to use and saving space.

It should be noted that, the specific structure of the second horizontal sliding mechanism 322 is not limited in the present utility model, as long as the second horizontal sliding mechanism 322 can drive the carrier 324 to move along the Y axis, and in practical application, a person skilled in the art can set the specific structure of the second horizontal sliding mechanism 322 according to actual needs. For example, the second horizontal sliding mechanism 322 may be configured in a manner that a motor drives a gear to rotate and is matched with a rack; alternatively, the second horizontal sliding mechanism 322 may be configured in a structure in which a motor drives a screw to rotate so as to drive the screw slider to move, and so on. Such modifications and changes in the specific structure of the second horizontal sliding mechanism 322 do not depart from the basic principle of the present utility model, and are intended to be within the scope of the present utility model.

Preferably, referring next to fig. 15 and 16, the tube picking apparatus 5 includes a third horizontal sliding mechanism 51, a freezing box fixing mechanism 52, and a tube picking device 53.

The first freezing storage box receiving and transferring device 31, the second horizontal sliding mechanism 322 and the code scanning device 4 are sequentially arranged along the Y axis, the tube picking device 53 and the code scanning device 4 are distributed at intervals along the X axis, and the freezing storage box fixing mechanism 52 can fix two freezing storage boxes at the same time; the third horizontal sliding mechanism 51 and the tube picking device 53 are connected with the box body 1, and the freezing box fixing mechanism 52 is arranged on the third horizontal sliding mechanism 51; the third horizontal sliding mechanism 51 is configured to drive the freezing box fixing mechanism 52 to move along the X-axis, so that the freezing box fixing mechanism 52 moves between the first box receiving position, the second box receiving position and the tube picking position; the frozen box holding mechanism 52 is capable of interfacing with the rotary shovel disk mechanism 316 at a first box-receiving position and with the second horizontal transfer mechanism 317 at a second box-receiving position to receive and transfer frozen boxes; the tube picking device 53 is provided so as to be able to perform a tube picking operation on the cryopreservation cassette located on the cryopreservation cassette holding means 52 at the tube picking position.

Through such setting, can save space, reduced the complexity of choosing pipe equipment 5 to second horizontal sliding mechanism 322 drives the fixed mechanism 52 of cryopreservation box and removes along the X axle, can make the fixed mechanism 52 of cryopreservation box connect box position, second to connect box position and choose between the pipe position, can improve the beat that automatic transfer, thereby improve and choose the pipe, sweep the sign indicating number and the efficiency that the cryopreservation box was transported, more convenient application.

Preferably, with continued reference to FIG. 16, the third horizontal sliding mechanism 51 includes an eighth drive 511 (e.g., a servo motor or stepper motor), a third lead screw 512, a third lead screw slider 513, and a fourth guide assembly 514.

The eighth driving piece 511 and the third screw rod 512 are installed on the base, the third screw rod 512 extends along the X axis, the freezing box fixing mechanism 52 is connected with the third screw rod slide block 513, the third screw rod slide block 513 is sleeved on the third screw rod 512 and is in threaded connection with the third screw rod 512, and the eighth driving piece 511 is connected with the third screw rod 512 and can drive the third screw rod 512 to rotate, so that the third screw rod slide block 513 and the freezing box fixing mechanism 52 are driven to move along the X axis; the fourth guiding component 514 is located between the base and the third screw slider 513, and the fourth guiding component 514 can guide the third screw slider 513 during the movement of the third screw slider 513 along the X axis, so as to make the third screw slider 513 move linearly and avoid the third screw slider 513 from rotating.

The third horizontal sliding mechanism 51 is provided as an eighth driving part 511, a third screw 512, a third screw slider 513 and a fourth guiding assembly 514, and has a simple structure and is convenient to assemble and use.

Preferably, with continued reference to fig. 16, the fourth guide assembly 514 includes a second guide rod 5141 and a second guide ring 5142 sleeved on the second guide rod 5141, the second guide rod 5141 is mounted on the base and extends along the X axis, the second guide ring 5142 can move along the second guide rod 5141, and the second guide ring 5142 is connected with the third screw slider 513.

In other embodiments, the fourth guide assembly 514 includes a guide rail and a guide slider slidably disposed with the guide rail, the guide rail being mounted on the base and extending along the X-axis, the guide slider being connected to the third lead screw slider 513.

It should be noted that, the specific structure of the fourth guiding assembly 514 is not limited in the present utility model, and in practical application, only the fourth guiding assembly 514 can guide the third screw slider 513 so that the third screw slider 513 moves linearly, and a person skilled in the art can set the specific structure of the fourth guiding assembly 514 according to the actual needs. The specific implementation of the fourth guide assembly 514 in the above embodiment should not limit the scope of the present utility model.

Preferably, the number of the fourth guiding assemblies 514 is two, and the fourth guiding assemblies are respectively positioned at two sides of the third screw rod 512.

The fourth guiding components 514 are respectively arranged on two sides of the third screw rod 512, so that the third screw rod sliding block 513 can be effectively prevented from rotating, and guiding and limiting effects are improved.

Preferably, with continued reference to fig. 16, the freezing box fixing mechanism 52 includes a first supporting seat 521 and a first box carrying platform 522 mounted on the first supporting seat 521, and two placing positions for placing the freezing boxes are arranged on the first box carrying platform 522 side by side along the X axis. The first supporting seat 521 is used for supporting and installing a first box carrying platform 522, and the first box carrying platform 522 is provided with two freezing boxes at the same time so as to be matched with the pipe picking device 53 for pipe picking operation.

Preferably, referring next to fig. 17 and 18, the tube picking device 53 includes a first connector 531, a second lifting mechanism 532, a second connector 533, a fourth horizontal sliding mechanism 534, and a tube picking jaw 535.

Wherein, the first connecting piece 531 is connected with the box 1, the second lifting mechanism 532 is installed on the first connecting piece 531, the second connecting piece 533 is installed on the second lifting mechanism 532, the fourth horizontal sliding mechanism 534 is installed on the second connecting piece 533, and the pipe picking clamping jaw 535 is installed on the fourth horizontal sliding mechanism 534; the second lifting mechanism 532 is configured to drive the second connecting member 533, the fourth horizontal sliding mechanism 534, and the pipe picking claw 535 to move along the Z-axis relative to the first connecting member 531, and the fourth horizontal sliding mechanism 534 is configured to drive the pipe picking claw 535 to move along the Y-axis relative to the second connecting member 533; the tube picking clamp 535 is capable of clamping a cryopreserved tube.

By such arrangement, the tube picking device 53 is more compact, and the volume of the tube picking device 53 can be reduced.

It should be noted that, the present utility model does not limit the specific structure of the second lifting mechanism 532, as long as the second lifting mechanism 532 can drive the second connecting member 533, the fourth horizontal sliding mechanism 534 and the pipe picking clamping jaw 535 to move along the Z axis (vertical direction), and in practical application, a person skilled in the art can set the specific structure of the second lifting mechanism 532 according to actual needs. For example, the second lifting mechanism 532 may be configured in such a manner that a motor drives a gear to rotate and cooperates with a rack, or the second lifting mechanism 532 may be configured in such a manner that a motor drives a screw to rotate and thereby drives a screw slider to move, or the like. Such modifications and changes in the specific structure of the second elevating mechanism 532 do not depart from the basic principle of the present utility model and should be limited to the scope of the present utility model.

It should be noted that, the present utility model also does not limit the specific structure of the fourth horizontal sliding mechanism 534, as long as the fourth horizontal sliding mechanism 534 can drive the pipe picking claw 535 to move along the Y axis, and in practical application, a person skilled in the art can set the specific structure of the fourth horizontal sliding mechanism 534 according to practical needs. For example, the fourth horizontal sliding mechanism 534 may be configured in such a manner that a motor drives a gear to rotate and cooperates with a rack; alternatively, the fourth horizontal sliding mechanism 534 may be configured in such a manner that a motor drives the screw to rotate, thereby driving the screw slider to move, and so on. Such modifications and changes in the specific structure of the fourth horizontal sliding mechanism 534 do not depart from the basic principle of the present utility model, and should be limited to the scope of the present utility model.

Preferably, with continued reference to fig. 17 and 18, the tube picking apparatus 5 further includes a tube pushing device 54, where the tube pushing device 54 is configured to push out the frozen tubes in the frozen boxes on the frozen box fixing mechanism 52 at the tube picking position, so that the tube picking device 53 picks the tubes smoothly.

A push bench 54 is provided for ejecting the freeze pipe upward so that the pick-up clamp claw 535 smoothly clamps the freeze pipe.

Preferably, referring to fig. 17 and 18, the push bench 54 includes a third connecting member 541, a third elevating mechanism 542 and a push bench 543; the third connecting member 541 is connected to the pipe picking claw 535, the third lifting mechanism 542 is mounted on the third connecting member 541, the pipe jacking piece 543 is connected to the third lifting mechanism 542, and the third lifting mechanism 542 is configured to drive the pipe jacking piece 543 to move along the Z axis, and the pipe jacking head of the pipe jacking piece 543 is located right below the pipe picking claw 535 and is opposite to the pipe picking claw 535.

By the arrangement mode, the pipe jacking device 54 and the pipe picking clamping jaw 535 share one lifting mechanism and one moving mechanism on the Y axis, the complexity of the pipe jacking device 54 is reduced, the cost is reduced, the size of the pipe picking equipment 5 is reduced, in addition, the pipe picking clamping jaw 535 and the pipe jacking piece 543 synchronously run in the horizontal direction, the matched progress of the pipe jacking jaw 535 and the pipe jacking piece 543 can be improved, and the pipe jacking device is convenient to use.

Although in the above embodiment, the push bench 54 is provided as the third link 541, the third elevating mechanism 542, and the push bench 543, this should not limit the scope of the present utility model. In practical applications, those skilled in the art may also configure the push bench 54 in other configurations. For example, the push bench 54 may be configured as the third connection element 541, and a Y-axis moving mechanism, a Z-axis moving mechanism, and a push pipe 543 mounted on the third connection element 541, where the Y-axis moving mechanism can drive the Z-axis moving mechanism and the push pipe 543 to move along the Y-axis, and the Z-axis moving mechanism can drive the push pipe 543 to move along the Z-axis, so that the push pipe 543 ejects the frozen storage pipe. Such modifications and changes in the specific structure of push bench 54 are not intended to depart from the basic principles of the present utility model and are intended to be within the scope of the present utility model.

Of course, the above-mentioned arrangement of the pipe jacking device 54 in the form of the third connecting member 541, the third lifting mechanism 542 and the pipe jacking member 543 is preferable, and the third connecting member 541 is connected to the pipe picking claw 535, so that the cost and the volume of the pipe picking apparatus 5 are reduced, and the application is more convenient.

It should be noted that, the specific structure of the third lifting mechanism 542 is not limited in the present utility model, as long as the third lifting mechanism 542 can drive the top tube 543 to move along the Z axis (vertical direction), and in practical application, a person skilled in the art can set the specific structure of the third lifting mechanism 542 according to practical needs. For example, the third elevating mechanism 542 may be configured to rotate by a motor driving a gear and to be engaged with a rack, or the third elevating mechanism 542 may be configured to rotate by a motor driving a screw to move a screw slider, or the like. Such modifications and changes in the specific structure of third elevating mechanism 542 do not depart from the basic principle of the present utility model and should be limited to the scope of the present utility model.

Preferably, the ambient temperature in the pick-up chamber 12 and the storage chamber 11 is from-120 ℃ to-70 ℃.

In other embodiments, the ambient temperature within the pick chamber 12 and the storage chamber 11 is-160 ℃. In practical applications, a person skilled in the art can set the ambient temperatures in the picking chamber 12 and the storage chamber 11 according to the actual storage requirement of the sample, and the temperatures in the above embodiments should not limit the protection scope of the present utility model.

Preferably, the ambient temperature within the sample receiving compartment 13 is from-30 ℃ to-10 ℃.

Preferably, the number of the storage compartments 11 is two, and the picking compartments 12 are located between the two storage compartments 11.

The number of the storage rooms 11 is two, and the pipe picking room 12 is positioned between the two storage rooms 11, so that one pipe picking room 12 is matched with the two storage rooms 11 for use, the duty ratio of the storage area in the box body 1 can be improved, and the storage utilization rate is improved.

In other embodiments, only one storage room 11 may be provided. The number of storage rooms 11 can be specifically set by those skilled in the art according to the actual situation, and the specific implementation forms in the above embodiment should not limit the scope of protection of the present utility model.

In addition, the biological sample storage library of the present utility model further comprises a motorized sealing door capable of opening and sealing the second access port 102, and a refrigerating system capable of refrigerating the picking chamber 12 and the storage chamber 11. In practical application, the electric sealing door is an automatic door in the prior art, and the specific structure of the electric sealing door is not repeated here; the refrigeration system may be configured as a liquid nitrogen refrigeration system, an air cooled refrigeration system, or other types of refrigeration systems, and the present utility model is not limited in any way by the particular configuration of the refrigeration system and the associated structure.

The operation flow of the biological sample storage library for storing the frozen storage boxes in batch in the warehouse is as follows:

first, the lifting mechanism 22 moves the transfer frame 23 to the first transfer position, at which time the second seal 234 seals the first access port 101.

Then, the second access opening 102 is opened, a plurality of frozen storage boxes are manually and quickly placed on the storage position 232 of the transfer frame 23 through the second access opening 102, the second access opening 102 is closed, and the lifting mechanism 22 moves the transfer frame 23 to the second transfer position.

Then, the shovel rotor mechanism 316 is abutted with the transfer frame 23 to take out the frozen storage box, and is abutted with the frozen storage box fixing mechanism 52 positioned at the first box receiving position under the drive of the first lifting mechanism 312 and the first horizontal sliding mechanism 314 to transfer the frozen storage box to the frozen storage box fixing mechanism 52.

Then, the third horizontal sliding mechanism 51 drives the freezing box fixing mechanism 52 to move to the second box receiving position, and the second horizontal transferring mechanism 317 moves the freezing box located on the freezing box fixing mechanism 52 to the code scanning device 4 for code scanning.

Finally, after the code scanning is completed, the second horizontal transfer mechanism 317 moves the frozen storage boxes from the code scanning device 4 to the second frozen storage box receiving and transferring device 3, and the frozen storage boxes are transferred into the storage room 11 by the second frozen storage box receiving and transferring device 3 so as to be in butt joint with the storage equipment in the storage room 11, until all the frozen storage boxes on the transferring frame 23 are stored into the storage room 11. The batch warehouse-out process is similar to the batch warehouse-in process, and the detailed steps are opposite.

The operation flow of the biological sample storage library according to the preferred embodiment of the present utility model for single-tube or multi-tube delivery of the frozen storage tube in the storage compartment 11 is as follows:

Then, the second inlet and outlet 102 is opened, the first horizontal transfer mechanism 24 operates to receive the empty frozen storage box located outside, and is lifted by the lifting mechanism 22, the empty frozen storage box is placed on the transfer frame 23, the second inlet and outlet 102 is closed, and the lifting mechanism 22 moves the transfer frame 23 to the second transfer position.

Then, the shovel rotor mechanism 316 is abutted with the transferring frame 23 to take out the empty frozen box, and is abutted with the frozen box fixing mechanism 52 positioned at the first box receiving position under the drive of the first lifting mechanism 312 and the first horizontal sliding mechanism 314 to transfer the empty frozen box to the No. 1 position of the frozen box fixing mechanism 52.

Then, the second frozen storage box receiving and transferring device 32 is in butt joint with the storage equipment in the storage room 11 to take out the target frozen storage box, the target frozen storage box is transferred to the second horizontal transfer mechanism 317, the target frozen storage box is transferred to the code scanning device 4 by the second horizontal transfer mechanism 317 to scan codes, and then the target frozen storage box is transferred to the No. 2 position of the frozen storage box fixing mechanism 52.

Then, the third horizontal sliding mechanism 51 drives the freezing box fixing mechanism 52 to move to the tube picking position, and the tube picking device 53 and the tube jacking device 54 cooperate to pick up and transfer the target freezing tubes into the empty freezing box.

Finally, after the tube is picked, the two freezing storage boxes are scanned again, after the code scanning is finished, the freezing storage boxes in the warehouse body are conveyed back into the storage room 11, and the original empty freezing storage boxes are output from the box body through the lifting and transferring device 2, so that the warehouse outlet operation of the specific freezing storage tubes is finished. The warehouse-in operation of the single-tube or multi-tube freezing storage tube is similar to the warehouse-out operation, and the detailed steps are opposite.

Thus far, the technical solution of the present utility model has been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of protection of the present utility model is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present utility model, and such modifications and substitutions will fall within the scope of the present utility model.

Claims

1. A biological sample repository, the biological sample repository comprising:

The box body is internally provided with a storage room, a picking pipe room and a sample receiving room, wherein the picking pipe room is communicated with the storage room and distributed along the Y-axis direction, the sample receiving room is positioned above the picking pipe room and is communicated with the picking pipe room through a first inlet and a second inlet, and the sample receiving room is communicated with the external environment of the box body through a second inlet and a second outlet;

a lifting and transferring device arranged in the sample receiving room, wherein the lifting and transferring device is arranged to transfer the freezing box between the picking pipe room and the sample receiving room through the first inlet and outlet, and is also arranged to transfer the freezing box between the sample receiving room and the outside through the second inlet and outlet;

the code scanning device is arranged in the tube picking room and is used for scanning a box code of the freezing box and a tube code of the freezing tube in the freezing box;

the tube picking device is arranged in the tube picking room and is used for picking tubes;

and

the frozen box transferring equipment is arranged in the picking pipe, and is arranged to be capable of transferring frozen boxes among the lifting transferring device, the picking pipe equipment, the code scanning device and the storage room.

2. The biological sample storage library of claim 1, wherein the lifting and transporting device comprises a first fixture, a lifting mechanism, a transporting rack, and a first horizontal transfer mechanism,

the first fixing piece is arranged in the sample receiving room, the lifting mechanism and the first horizontal transfer mechanism are arranged on the first fixing piece and positioned in the sample receiving room,

the transfer frame is connected with the lifting mechanism and passes through the first inlet and outlet, the transfer frame can place the freezing boxes in batches,

the lifting mechanism is arranged to drive the transfer frame to move along the Z axis so as to enable the transfer frame to move between a first transfer position and a second transfer position, the first transfer position is positioned in the sample receiving room, and the second transfer position is positioned in the picking room;

the first horizontal transfer mechanism is arranged to be capable of receiving and transferring the frozen storage box along the X axis, wherein in the condition that the transfer frame is located at the first transfer position, the transfer frame and the second inlet and outlet are arranged opposite to each other, the first horizontal transfer mechanism is capable of receiving the frozen storage box located on the transfer frame and conveying the frozen storage box to the external environment through the second inlet and outlet, and receiving the frozen storage box in the external environment through the second inlet and outlet and placing the frozen storage box on the transfer frame.

3. The biological sample storage library of claim 2, wherein the transfer rack comprises a rack body, wherein a plurality of storage positions are arranged in the rack body in an array along the length direction and the height direction of the rack body and form a plurality of columns and layers, each storage position is provided with a first opening and a second opening for taking and placing a freezing storage box, and the first opening and the second opening are oppositely arranged.

4. A biological sample storage library according to claim 3, wherein the top and bottom of the transfer rack are provided with a first seal and a second seal, respectively, the lifting mechanism being connected to the first seal,

the first seal seals the first access opening with the transfer frame in the second transfer position,

the second seal seals the first access opening with the transfer shelf in the first transfer position.

5. The biological sample storage library of claim 1, further comprising a transfer rack guide positioned within the picking chamber, the transfer rack guide being coupled to the transfer rack and capable of guiding the transfer rack during up and down movement of the transfer rack to provide for linear movement of the transfer rack.

6. The biological sample storage library of claim 1, wherein the cryopreservation cassette transfer apparatus comprises a first cryopreservation cassette receiving transfer device and a second cryopreservation cassette receiving transfer device,

the first freezing box receiving and transferring device is arranged to be capable of receiving and transferring freezing boxes along an X axis and a Y axis, and is capable of being respectively in butt joint with the lifting and transferring device, the pipe picking device, the code scanning device and the second freezing box receiving and transferring device so as to receive and transfer the freezing boxes;

the second cryopreservation cassette receiving and transporting device is configured to enable transfer of a cryopreservation cassette between the first cryopreservation cassette receiving and transporting device and the storage compartment.

7. The biological sample storage library of claim 6, wherein the first cryopreservation cassette receiving and transporting device comprises a first mount and a first lifting mechanism, a second mount, a first horizontal sliding mechanism, a third mount, a rotating shovel disk mechanism, and a second horizontal transfer mechanism mounted on the first mount;

the first mounting piece is connected with the box body, the second mounting piece is connected with the first lifting mechanism, the first horizontal sliding mechanism and the second horizontal transferring mechanism are mounted on the second mounting piece, the first horizontal sliding mechanism and the second horizontal transferring mechanism are distributed along the X-axis at intervals, the third mounting piece is connected with the first horizontal sliding mechanism, the rotary shovel disc mechanism is mounted on the third mounting piece,

The first lifting mechanism is arranged to drive the second mounting piece, the first horizontal sliding mechanism, the second horizontal transfer mechanism, the third mounting piece and the rotary shovel disk mechanism to move along a Z axis;

the first horizontal sliding mechanism is arranged to drive the third mounting piece and the rotary shovel disk mechanism to move along the Y axis, so that the rotary shovel disk mechanism can be in butt joint with the pipe picking device to transfer the freezing box;

the rotary shovel disc mechanism is arranged to be capable of rotating circumferentially around the vertical shaft and moving telescopically along the length direction of the rotary shovel disc mechanism so as to receive and transfer the freezing box;

the second horizontal transfer mechanism is arranged to be capable of receiving and transferring the cryopreservation box along the Y axis and transferring the cryopreservation box among the tube picking equipment, the code scanning device and the second cryopreservation box receiving and transferring device.

8. The biological sample storage library according to claim 7, wherein the code scanning device and the second horizontal transfer mechanism are distributed at intervals along the Y axis, and the first lifting mechanism drives the second horizontal transfer mechanism to move to be at the same height as the code scanning device, wherein the second horizontal transfer mechanism is opposite to the code scanning device.

9. The biological sample storage library of claim 7, wherein the second cryopreservation cassette receiving and transporting device comprises a first support and a second horizontal sliding mechanism mounted on the first support, a second support and a cassette carrier;

the second support piece is arranged on the second horizontal sliding mechanism, the box carrying piece is arranged on the second support piece, and the box carrying piece can carry the freezing box;

the second horizontal sliding mechanism is arranged to drive the second supporting piece and the box carrying piece to move along the Y axis so as to transfer the freezing box between the picking pipe and the storage room,

the box carrying pieces and the second horizontal transfer mechanisms are distributed at intervals along the Y axis, and the first lifting mechanism is arranged opposite to the box carrying pieces under the condition that the second horizontal transfer mechanisms are driven to move to the same height as the box carrying pieces;

and/or the number of the groups of groups,

the tube picking device comprises a third horizontal sliding mechanism, a freezing box fixing mechanism and a tube picking device, wherein the first freezing box receiving and transferring device, the second horizontal sliding mechanism and the code scanning device are sequentially arranged along a Y axis, the tube picking device and the code scanning device are distributed at intervals along an X axis, and the freezing box fixing mechanism can fix two freezing boxes at the same time;

The third horizontal sliding mechanism and the tube picking device are connected with the box body, and the freezing box fixing mechanism is arranged on the third horizontal sliding mechanism;

the third horizontal sliding mechanism is arranged to drive the freezing box fixing mechanism to move along the X axis so as to enable the freezing box fixing mechanism to move among a first box receiving position, a second box receiving position and a tube picking position;

the freezing box fixing mechanism can be in butt joint with the rotary shovel disc mechanism at the first box connecting position and can be in butt joint with the second horizontal transferring mechanism at the second box connecting position so as to receive and transfer the freezing box;

the tube picking device is arranged to be capable of picking the frozen box on the frozen box fixing mechanism at the tube picking position.

10. The biological sample storage library of claim 9, wherein the tube picking apparatus further comprises a tube jacking device configured to eject a frozen tube in a frozen box on the frozen box fixing mechanism at the tube picking position so that the tube picking device picks a tube smoothly.