CN220142328U - Pushing device for nucleated cells - Google Patents

Pushing device for nucleated cells Download PDF

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Publication number
CN220142328U
CN220142328U CN202321619795.5U CN202321619795U CN220142328U CN 220142328 U CN220142328 U CN 220142328U CN 202321619795 U CN202321619795 U CN 202321619795U CN 220142328 U CN220142328 U CN 220142328U
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Prior art keywords
piston
injection device
wall
hollow cylinder
cell injection
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CN202321619795.5U
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Chinese (zh)
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马洪松
李欣
马名威
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Fubin Biotechnology Tianjin Co ltd
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Fubin Biotechnology Tianjin Co ltd
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Abstract

The utility model discloses a pushing injection device for nucleated cells, which comprises an empty cylinder, wherein the bottom of the empty cylinder is communicated with a hole head, one end of the hole head is communicated and clamped with a needle head, a piston is arranged in the empty cylinder, the periphery of the outer wall of the piston is provided with an annular groove, a sealing rubber ring is sleeved in the annular groove, the upper surface of the piston is fixedly connected with one end of a piston rod, the other end of the piston rod is provided with a piston handle, an adhesive force plate is arranged at the opening of the top end of the empty cylinder, the adhesive force plate is connected with the piston handle through a piston jacking assembly, when the nucleated cells are extracted, a user only needs to observe the extraction amount through scale, when the predetermined extraction amount is reached, the user applies downward acting force to the piston handle to stop upward sliding of the piston handle, and the user does not need to actively exert force to enable the piston handle to move upward in the extraction process, so that the situation that the extraction efficiency is low and the device is possibly damaged due to the fact that the extraction is carried out in an uncomfortable posture can be avoided.

Description

Pushing device for nucleated cells
Technical Field
The utility model relates to the field of nucleated cells, in particular to a pushing device of the nucleated cells.
Background
By medically nucleated cells is meant cells having nuclei, such as leukocytes, lymphocytes, monocytes, plasma cells, macrophages and the like in the peripheral blood. Furthermore, whether blood cells have nuclei is intimately involved in their functional evolution. In order to better exert the function of transporting oxygen, the erythrocytes pass through 5 stages of primitive erythrocytes, premature erythrocytes, middle-young erythrocytes, late-young erythrocytes and reticulocytes, and become mature erythrocytes after the nuclei are removed. The cytoplasm of the mature red blood cells contains a large amount of hemoglobin, the nucleus is removed so as to carry more oxygen, and clinically, blood diseases such as acute blood loss, leukemia, hemolytic anemia, myelodysplastic syndrome and the like can be identified by detecting nucleated cells, and the prognosis of some diseases can be simply judged and evaluated. The principle is that mature red blood cells in a normal state have no cell nucleus, if nucleated red blood cells can be seen in peripheral blood, the red blood cells belong to a pathological state, a subject possibly has the blood diseases, stem cell injection is a method for intravenous injection of stem cells, the stem cell injection has the functions of improving and pre-diabetes, improving and preventing 'three highs', improving and preventing heart function decline, improving brain function decline (memory and intelligence), improving and preventing liver function decline, preventing immune system decline, improving and preventing female premature ovarian failure and climacteric syndrome, improving and preventing male sexual function decline and prostatic hyperplasia, improving and preventing muscle function decline, and the like, and most of injectors which are commonly used in the market at present are syringe injectors, but injection scales cannot be well mastered in the use process of the syringe injectors can only be observed empirically, and operation errors of the injection quantity exist, so the application number: CN202020489822.1 discloses a nucleated cell injection device, which comprises a cylinder, a sleeve, a graduated scale, a piston rod, a push plate, a barrel cover and a baffle plate. When the stem cell injection device is used, firstly, the injection head is sleeved on the liquid outlet head, then the push plate is extruded, air in the cylinder body is discharged, at the moment, the injection head is inserted into the stem cell preservation bottle, at the moment, the push plate is pushed, stem cells are pumped into the cylinder body from the injection head through the liquid outlet head, at the moment, a user rotates the sleeve, the tube cover is enabled to touch the baffle plate, at the moment, the user rotates the sleeve according to the required injection quantity, the relative position of the bottom edge of the sleeve on the graduated scale is adjusted, then the injection head is inserted into a vein of a user to be injected, then the push plate is pressed, the baffle plate is enabled to touch the tube cover, and meanwhile, the push plate drives the piston to extrude stem cell solution in the cylinder body through the piston rod, so that the stem cell solution in the cylinder body enters the injection head through the liquid outlet head and is pushed into the body of the user to complete injection work.
However, the inventor has found that in the above-mentioned scheme, in the process of extracting nucleated cells to the cylinder, the user is inconvenient to operate by a single hand to lift the piston rod, the piston rod needs to be pulled by the other hand of the hand-held cylinder, or the piston rod is held by a single hand, the thumb and the index finger are bent and abutted against the lifting ring, then the index finger of the thumb is straightened to complete the displacement of the driving piston, the efficiency of the mode of completing the extraction by two hands is low, in some cases, the user may need to hold other containers by the other hand, the inconvenience in use is caused, in the process of operating by the single hand, the length of the extension of the index finger of the thumb is limited, the extraction amount of one action is limited, the operation needs to be circulated for many times, in the process of extending the fingers, the direction of force between the fingers and the palm is not straight line, the piston rod is inclined relative to the cylinder when the piston rod is pulled, and the possibility of deformation and fracture at the connection position of the piston rod and the piston rod exists, and the service life is reduced.
How to invent a nucleated cell injection device to improve these problems becomes a urgent problem for those skilled in the art.
Disclosure of Invention
In order to make up for the defects, the utility model provides a pushing device for nucleated cells, which aims to improve the problems that in the process of extracting nucleated cells to a cylinder body, a user cannot conveniently operate by one hand to drive a piston rod to lift, the piston rod needs to be pulled by the other hand of the cylinder body, or the piston rod is held by one hand, a thumb and an index finger are bent to be abutted against a lifting ring, and then the thumb and the index finger are straightened to complete the displacement of driving the piston, and the efficiency of the mode of completing the extraction by two hands is lower.
The utility model is realized in the following way: the utility model provides a have a nuclear cell's injection device, includes an empty section of thick bamboo, empty section of thick bamboo bottom intercommunication is provided with the hole head, hole head one end intercommunication block has the syringe needle, the inside piston that is provided with of empty section of thick bamboo, piston outer wall border is provided with the ring channel, the ring channel endotheca is equipped with sealed rubber ring, the last fixed surface of piston is connected with the one end of piston rod, the other end of piston rod is provided with the piston handle, empty section of thick bamboo top opening part is provided with the acting plate, be connected through the piston jacking subassembly between acting plate and the piston handle, the piston jacking subassembly includes two spouts that set up in acting plate upper surface both ends, every slidable mounting has the slider in the spout, every slider top surface is provided with first U type articulated frame, every fixedly connected with first installation axle between the inner wall of first U type articulated frame both sides, every the last one end that articulates the connecting rod has, every the other end articulates in the second U type articulated frame inner wall that corresponds one side sets up, two first U type articulated frame are arranged on the second articulated frame inner wall that two sets up, two first U type articulated frame bottom are arranged in the surface of acting plate is located the one side of piston rod one side, the fixed surface is located the one end of each fixed surface of reset spring and is connected to one side of the slider.
In a preferred technical scheme of the utility model, the hollow cylinder is made of transparent medical PVC material.
In a preferred technical scheme of the utility model, the hollow cylinder, the hole head and the force plate are integrally formed.
In a preferred technical scheme of the utility model, the outer wall of the hollow cylinder is provided with scale marks.
In a preferred technical scheme of the utility model, the number of the scale marks is two, and the scale marks are respectively arranged on the outer walls of the two sides of the hollow cylinder.
In a preferred technical scheme of the utility model, protruding parts are arranged at two ends of the force exerting plate to prolong the length of the sliding groove, so that the slidable distance of the sliding block is matched with the displaceable distance of the piston in the hollow cylinder.
In a preferred embodiment of the present utility model, the ends of the protruding portions at both ends of each of the force plates are disposed in an arc shape.
In a preferred technical scheme of the utility model, the diameter of the outer wall of the piston is matched with the diameter of the inner wall of the hollow cylinder, and the thickness of the sealing rubber ring is slightly larger than the depth of the annular groove.
In a preferred embodiment of the present utility model, the piston rod and the piston stem are integrally formed.
The beneficial effects of the utility model are as follows: according to the nucleated cell pushing and injecting device, when the piston handle is pressed down to enable the piston to be located at the bottom end of the empty cylinder, the piston handle is driven to move upwards through the piston jacking assembly after the piston handle is pressed down, so that the piston is pulled to complete the extraction action, in the process, a user only needs to observe the extraction amount through the scale mark, when the preset extraction amount is reached, the user applies downward acting force to the piston handle to enable the piston handle to stop sliding upwards, then the piston handle is pressed again to enable nucleated cells in the empty cylinder to be pushed and injected, and in the extraction process, the user does not need to actively exert force to enable the piston handle to move upwards, so that the situation that extraction efficiency is low and the device is possibly damaged due to uncomfortable posture to extraction can be avoided.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some examples of the present utility model and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic perspective view of the overall structure provided by an embodiment of the present utility model;
FIG. 2 is a schematic perspective view of an overall cross-sectional structure provided by an embodiment of the present utility model;
FIG. 3 is a schematic perspective view of the overall structure of a piston jack assembly according to an embodiment of the present utility model;
FIG. 4 is a schematic perspective view of an enlarged structure at B in FIG. 3 provided in accordance with an embodiment of the present utility model;
fig. 5 is a schematic perspective view of an enlarged structure at a in fig. 2 according to an embodiment of the present utility model.
In the figure: 1-an empty cylinder; 101-a chute; 102-a slider; 103-a first U-shaped hinge bracket; 104-a connecting rod; 105-a second U-shaped hinge bracket; 106-a return spring; 2-hole heads; 3-a needle; 4-a piston; 5-sealing rubber rings; 6-a piston rod; 7-a piston stem; 8-a force plate; 9-a piston jack assembly; 10-scale mark.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments. All other embodiments, based on the embodiments of the utility model, which are apparent to those of ordinary skill in the art without inventive faculty, are intended to be within the scope of the utility model.
Referring to fig. 1 to 5, the present utility model provides a technical solution: the utility model provides a have pushing away annotate device of nucleated cell, including empty section of thick bamboo 1, empty section of thick bamboo 1 bottom intercommunication is provided with hole head 2, hole head 2 one end intercommunication block has syringe needle 3, the inside piston 4 that is provided with of empty section of thick bamboo 1, piston 4 outer wall border is provided with the ring channel, the ring channel endotheca is equipped with sealed rubber ring 5, the last fixed surface of piston 4 is connected with the one end of piston rod 6, the other end of piston rod 6 is provided with piston handle 7, empty section of thick bamboo 1 top opening part is provided with the adhesive force board 8, connect through piston jacking subassembly 9 between adhesive force board 8 and the piston handle 7, piston jacking subassembly 9 includes two spouts 101 that set up in the upper surface both ends of adhesive force board 8, slidable mounting has slider 102 in every spout 101, every slider 102 top surface is provided with first U type articulated frame 103, fixedly connected with first installation axle between the inner wall of every first U type articulated frame 103 both sides, the one end of connecting rod 104 is articulated on every first installation axle, the other end of connecting rod 104 articulates on the second U type articulated frame 105 of corresponding one side, on the second articulated axle that sets up between the inner wall of piston rod 6, two second U type articulated frame 105 are located the one side of one end of fixed surface of each side of slider 106, the slider is located the fixed surface of the one end of connecting spring 106 of each side of connecting spring 106.
Furthermore, the hollow cylinder 1 is made of transparent medical PVC material, which has the advantages of low cost, wide application range, easy processing, good chemical resistance and the like, and the transparent material is convenient for a user to observe the liquid level condition in the hollow cylinder 1, thereby improving the use convenience.
Further, the hollow cylinder 1, the hole head 2 and the force-exerting plate 8 are integrally formed, in actual pushing or drawing use, a user mostly adopts middle fingers and index fingers to clamp on two sides of the force-exerting plate 8, thumbs press on the piston handle 7 to push, and the hole head 2 is used as a component connected with the needle head 3, and can bear certain acting force under certain conditions and angles, so that the hollow cylinder 1, the hole head 2 and the force-exerting plate 8 are integrally formed according to the component which usually needs to be stressed, the overall structural strength can be relatively improved, and the stability and the service life in use are improved.
Referring to fig. 1, a scale mark 10 is provided on the outer wall of the hollow cylinder 1, and the volume of the bolus or extraction can be accurately observed by setting the scale mark 10, so that the accuracy of the bolus or extraction is ensured.
Further, the number of the scale marks 10 is two, and the scale marks 10 are respectively arranged on the outer walls of the two sides of the hollow cylinder 1, so that the design can ensure that the user can conveniently observe the capacity of pushing or extracting through the scale marks 10 no matter the user operates the device by the right hand or the left hand, thereby reducing the limitation in use.
Referring to fig. 1 to 3, the two ends of the force plate 8 are provided with protruding portions to extend the length of the sliding groove 101, so that the slidable distance of the sliding block 102 is adapted to the displaceable distance of the piston 4 in the hollow cylinder 1, when the piston 4 is pushed to the bottom of the hollow cylinder 1, the sliding block 102 slides to the end of the sliding groove 101 located outside, when the piston 4 is pulled to the top of the hollow cylinder 1, the sliding block 102 slides to the end of the sliding groove 101 close to the piston rod 6, and by providing protruding portions to extend the length of the sliding groove 101, the sliding block 102 can slide to be adapted to the piston 4.
Further, the protruding parts at the two ends of each force applying plate 8 are arranged in an arc shape, and the protruding parts extend longer, so that the arc-shaped end parts can avoid the sharp parts from scratching human bodies or other objects, and the use safety is improved.
Referring to fig. 2, the diameter of the outer wall of the piston 4 is adapted to the diameter of the inner wall of the hollow cylinder 1, the thickness of the sealing rubber ring 5 is slightly larger than the depth of the annular groove, and the sealing rubber ring 5 can be tightly attached to the inner wall of the hollow cylinder 1, so that the air tightness is ensured, and the conditions of air leakage, liquid seepage and the like are avoided.
Furthermore, the piston 4, the piston rod 6 and the piston handle 7 are integrally formed, so that the overall strength is improved, the situation that deformation and fracture occur at the joint between the piston 4, the piston rod 6 and the piston handle 7 is avoided, and the service life is prolonged relatively.
Working principle: before the nucleated cells are extracted into the hollow cylinder 1, a user firstly pushes the piston handle 7 to drive the piston 4 to descend and discharge air in the hollow cylinder 1, the needle 3 is inserted into a container for storing the nucleated cells, then the piston handle 7 is loosened, the sliding block 102 is pushed to slide in the sliding groove 101 under the elastic acting force of the return spring 106, so that one end of the connecting rod 104 is driven to displace to one side of the piston rod 6, the other end of the connecting rod 104 is driven to displace upwards to jack up the piston handle 7, and the piston 4 is driven to lift up to extract the nucleated cells, in the process, the user only needs to observe the extraction amount through the scale mark 10, when the preset extraction amount is reached, the user applies downward acting force to the piston handle 7 to stop the upward sliding of the piston handle 7, then the piston handle 7 is pushed again, the nucleated cells in the hollow cylinder 1 can be injected, the user does not need to actively exert force again to displace the piston handle 7 upwards to complete the extraction action, and the extraction action can be avoided, and the device can be damaged because the extraction is not efficient due to uncomfortable postures.
The above description is only of the preferred embodiments of the present utility model and is not intended to limit the present utility model, and various modifications and variations may be made to the present utility model by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.

Claims (9)

1. The utility model provides a have a nuclear cell's injection device, its characterized in that, including an empty section of thick bamboo, empty section of thick bamboo bottom intercommunication is provided with the hole head, hole head one end intercommunication block has the syringe needle, the inside piston that is provided with of an empty section of thick bamboo, piston outer wall border is provided with the ring channel, the ring channel endotheca is equipped with sealed rubber ring, the last fixed surface of piston is connected with the one end of piston rod, the other end of piston rod is provided with the piston handle, empty section of thick bamboo top opening part is provided with the impetus board, connect through the piston jacking subassembly between impetus board and the piston handle, the piston jacking subassembly includes two spouts that set up in impetus board upper surface both ends, every slidable mounting has the slider in the spout, every slider top surface is provided with first U type articulated frame, every fixedly connected with first installation axle between the inner wall of first U type articulated frame both sides, every the last one end that articulates the connecting rod, every the other end articulates in the second U type articulated frame inner wall that corresponds one side sets up, two first articulated frame inner walls are provided with the impetus board, two the second articulated frame sets up on the second articulated shaft, two articulated frame that are located the one side of piston rod one end is located the fixed surface of each side of the reset spring, one end is connected to one side of the fixed surface of the reset spring.
2. The nucleated cell injection device of claim 1, wherein: the hollow cylinder is made of transparent medical PVC material.
3. The nucleated cell injection device of claim 1, wherein: the hollow cylinder, the hole head and the force applying plate are integrally formed.
4. The nucleated cell injection device of claim 1, wherein: the outer wall of the hollow cylinder is provided with scale marks.
5. The nucleated cell injection device of claim 4, wherein: the number of the scale marks is two, and the scale marks are respectively arranged on the outer walls of the two sides of the empty cylinder.
6. The nucleated cell injection device of claim 1, wherein: the two ends of the force exerting plate are provided with protruding parts to prolong the length of the sliding groove, so that the slidable distance of the sliding block is matched with the displaceable distance of the piston in the hollow cylinder.
7. The nucleated cell injection device of claim 6, wherein: the ends of the protruding parts at the two ends of each force plate are arranged in an arc shape.
8. The nucleated cell injection device of claim 1, wherein: the diameter of the outer wall of the piston is matched with the diameter of the inner wall of the hollow cylinder, and the thickness of the sealing rubber ring is slightly larger than the depth of the annular groove.
9. The nucleated cell injection device of claim 1, wherein: the piston, the piston rod and the piston handle are integrally formed.
CN202321619795.5U 2023-06-26 2023-06-26 Pushing device for nucleated cells Active CN220142328U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202321619795.5U CN220142328U (en) 2023-06-26 2023-06-26 Pushing device for nucleated cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202321619795.5U CN220142328U (en) 2023-06-26 2023-06-26 Pushing device for nucleated cells

Publications (1)

Publication Number Publication Date
CN220142328U true CN220142328U (en) 2023-12-08

Family

ID=89014292

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202321619795.5U Active CN220142328U (en) 2023-06-26 2023-06-26 Pushing device for nucleated cells

Country Status (1)

Country Link
CN (1) CN220142328U (en)

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