CN220137482U - Light sheet fluorescence microscope - Google Patents

Light sheet fluorescence microscope Download PDF

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Publication number
CN220137482U
CN220137482U CN202320318061.7U CN202320318061U CN220137482U CN 220137482 U CN220137482 U CN 220137482U CN 202320318061 U CN202320318061 U CN 202320318061U CN 220137482 U CN220137482 U CN 220137482U
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CN
China
Prior art keywords
light
objective table
positioning
fluorescence microscope
dimming
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Active
Application number
CN202320318061.7U
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Chinese (zh)
Inventor
亓立峰
郑顺利
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Shanghai Nao Biotechnology Co ltd
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Shanghai Nao Biotechnology Co ltd
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Priority to CN202320318061.7U priority Critical patent/CN220137482U/en
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Publication of CN220137482U publication Critical patent/CN220137482U/en
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Abstract

The utility model discloses a light sheet fluorescence microscope, which comprises a base, wherein a support frame is arranged on the base, an observation mirror assembly is arranged on the support frame, an objective table is arranged on the base, a light source assembly is arranged at the bottom of the objective table, and a light through hole is formed in the objective table; the device is characterized in that a dimming mechanism is arranged at the bottom of the objective table; the light adjusting mechanism comprises a positioning cylinder arranged at the bottom of the objective table, a front lead screw and a back lead screw and a limiting polished rod are arranged in the positioning cylinder, and a moving block which moves in opposite directions is arranged on the front lead screw and the back lead screw; the dimming mechanism for dimming the light through holes is used for dimming, and the light reaches the use requirement, wherein the dimming mechanism drives the two moving blocks to move by the positive and negative screw rods, so that the two light shielding sheets are driven to move relatively, and the light shielding effect is achieved. The structure has the advantages of simple structure and easy adjustment.

Description

Light sheet fluorescence microscope
Technical Field
The utility model relates to the technical field of microscopes, in particular to a light sheet fluorescence microscope.
Background
A microscope is an optical instrument composed of a lens or a combination of several lenses, and is a sign of human entry into the atomic age.
The device is used for amplifying tiny objects into instruments which can be seen by naked eyes of people and is mainly divided into an optical microscope and an electron microscope; in the light sheet fluorescence microscope, excitation light with a specific wavelength is selected from illumination light of a specimen to generate fluorescence, and then the fluorescence must be separated singly for observation in light of a mixture of the excitation light and the fluorescence. Therefore, the filter system becomes an extremely important role in selecting a specific wavelength. In the practical process, the illumination needs to be adjusted, and the existing adjusting mechanism has complex structure and difficult assembly.
Disclosure of Invention
In order to solve the defects that the prior art needs to adjust illumination in the practical process, and the prior adjusting mechanism has complex structure and difficult assembly, the utility model provides a light sheet fluorescence microscope.
In order to solve the technical problems, the utility model provides the following technical scheme:
the utility model relates to a light sheet fluorescence microscope, which comprises a base, wherein a support frame is arranged on the base, an observation mirror assembly is arranged on the support frame, an objective table is arranged on the base, a light source assembly is arranged at the bottom of the objective table, and a light through hole is formed in the objective table; the device is characterized in that a dimming mechanism is arranged at the bottom of the objective table; and the dimming mechanism comprises a positioning cylinder arranged at the bottom of the objective table, a positive and negative screw rod and a limiting polish rod are arranged in the positioning cylinder, a moving block which moves in opposite directions is arranged on the positive and negative screw rod, a limiting sleeve which moves along the limiting polish rod is arranged on the limiting polish rod, a shading sheet is fixed on the moving block, and a rotating handle connected with the shaft end of the positive and negative screw rod is arranged on the positioning cylinder.
As a preferable technical scheme of the utility model, the positioning cylinder is provided with a light blocking sheet matched with the light shielding sheet.
As a preferable embodiment of the present utility model, the stage is provided with a positioning groove for positioning the slide glass.
As a preferable technical scheme of the utility model, the two light shielding sheets are provided with semicircular grooves which are matched with each other.
As a preferable technical scheme of the utility model, the positioning cylinder is provided with a positioning flange plate, and the positioning flange plate is fixed with the bottom of the objective table.
The beneficial effects of the utility model are as follows:
the light-dimming mechanism for dimming the light-passing hole is arranged at the bottom of the objective table, so that the light reaches the use requirement, and the light-dimming mechanism drives the two moving blocks to move by the positive and negative screw rods, so that the two light-shielding sheets are driven to perform relative movement, and the light-shielding effect is achieved. The structure has the advantages of simple structure and easy adjustment.
Drawings
The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model. In the drawings:
FIG. 1 is a schematic diagram of a light sheet fluorescence microscope according to the present utility model;
FIG. 2 is a schematic diagram of a moving block of a light sheet fluorescence microscope according to the present utility model;
fig. 3 is a schematic structural view of a light shielding sheet of a light sheet fluorescence microscope according to the present utility model.
In the figure: 1. a base; 2. a support frame; 3. a scope assembly; 4. a light source assembly; 5. a light-transmitting hole; 6. a light adjusting mechanism; 7. a positioning cylinder; 8. a positive and negative screw rod; 9. limiting a polished rod; 10. a moving block; 11. a limit sleeve; 12. a light shielding sheet; 13. a semicircular groove; 14. rotating the handle; 15. a light blocking sheet; 16. a positioning groove; 17. positioning a flange plate; 18. and a stage.
Detailed Description
The preferred embodiments of the present utility model will be described below with reference to the accompanying drawings, it being understood that the preferred embodiments described herein are for illustration and explanation of the present utility model only, and are not intended to limit the present utility model.
Examples: as shown in fig. 1, 2 and 3, the light sheet fluorescence microscope of the present utility model comprises a base 1, wherein a support frame 2 is provided on the base 1, a viewer assembly 3 is provided on the support frame 2, a stage 18 is provided on the base, a light source assembly 4 is provided at the bottom of the stage 18, and a light hole 5 is provided on the stage; the device is characterized in that a dimming mechanism 6 for dimming the light passing hole 5 is arranged at the bottom of the objective table 18; and dimming mechanism 6 is including setting up the positioning tube 7 in objective table 18 bottom, just be equipped with positive and negative lead screw 8 and spacing polished rod 9 in the positioning tube 7, just be equipped with the movable block 10 of motion in opposite directions on the positive and negative lead screw 8, be equipped with the stop collar 11 that removes along spacing polished rod 9 on the spacing polished rod 9, just be fixed with the anti-dazzling screen 12 on the movable block 10, be equipped with the twist grip 14 that is connected with positive and negative lead screw 8's axle head on the positioning tube 7. The dimming mechanism 6 for dimming the light through hole 5 is arranged at the bottom of the objective table 18, so that the light reaches the use requirement, wherein the dimming mechanism 6 is driven by the positive and negative screw rod 8 to move by the two moving blocks 10, and further drives the two light shielding sheets 12 to perform relative movement, thereby playing a role in shielding light. The structure has the advantages of simple structure and easy adjustment.
Wherein, the positioning cylinder 7 is provided with a light blocking sheet 15 matched with the light shielding sheet 12. Shading between the shading sheet and the inner wall of the positioning cylinder by utilizing the shading sheet
Wherein, the objective table 18 is provided with a positioning groove 16 for positioning the slide glass, so as to position the slide glass conveniently.
Wherein, two anti-dazzling screens 12 are equipped with the semicircle groove 13 of mutually supporting, when anti-dazzling screen motion, play the effect of adjusting the size of light, and the illumination is to it with the light-passing opening all the time.
The positioning cylinder 7 is provided with a positioning flange 17, and the positioning flange 17 is fixed with the bottom of the objective table 18, so that the positioning flange is convenient to fix.
Working principle: the dimming mechanism 6 for dimming the light through hole 5 is arranged at the bottom of the objective table 18, so that the light reaches the use requirement, wherein the dimming mechanism 6 is driven by the positive and negative screw rod 8 to move by the two moving blocks 10, and further drives the two light shielding sheets 12 to perform relative movement, thereby playing a role in shielding light. The structure has the advantages of simple structure and easy adjustment.
Finally, it should be noted that: the foregoing description is only a preferred embodiment of the present utility model, and the present utility model is not limited thereto, but it is to be understood that modifications and equivalents of some of the technical features described in the foregoing embodiments may be made by those skilled in the art, although the present utility model has been described in detail with reference to the foregoing embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.

Claims (5)

1. The light sheet fluorescence microscope comprises a base (1), wherein a support frame (2) is arranged on the base (1), an observation mirror assembly (3) is arranged on the support frame (2), an objective table (18) is arranged on the base, a light source assembly (4) is arranged at the bottom of the objective table (18), and a light through hole (5) is formed in the objective table; the device is characterized in that a dimming mechanism (6) for dimming the light passing hole (5) is arranged at the bottom of the objective table (18); and dimming mechanism (6) is including setting up the positioning tube (7) in objective table (18) bottom, just be equipped with positive and negative lead screw (8) and spacing polished rod (9) in positioning tube (7), just be equipped with movable block (10) of motion in opposite directions on positive and negative lead screw (8), be equipped with on spacing polished rod (9) along stop collar (11) that spacing polished rod (9) removed, just be fixed with on movable block (10) anti-dazzling screen (12), be equipped with on positioning tube (7) with positive and negative lead screw (8) axle head be connected twist grip (14).
2. The light sheet fluorescence microscope according to claim 1, characterized in that the positioning cylinder (7) is provided with a light blocking sheet (15) matched with the light blocking sheet (12).
3. An optical sheet fluorescence microscope according to claim 1 characterised in that the stage (18) is provided with a positioning slot for positioning the slide.
4. A light sheet fluorescence microscope according to claim 1 characterised in that the two light shields (12) are provided with mutually cooperating semicircular grooves (13).
5. The light sheet fluorescence microscope according to claim 1, characterized in that a positioning flange (17) is arranged on the positioning cylinder (7), and the positioning flange (17) is fixed with the bottom of the objective table (18).
CN202320318061.7U 2023-02-27 2023-02-27 Light sheet fluorescence microscope Active CN220137482U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202320318061.7U CN220137482U (en) 2023-02-27 2023-02-27 Light sheet fluorescence microscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202320318061.7U CN220137482U (en) 2023-02-27 2023-02-27 Light sheet fluorescence microscope

Publications (1)

Publication Number Publication Date
CN220137482U true CN220137482U (en) 2023-12-05

Family

ID=88951116

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202320318061.7U Active CN220137482U (en) 2023-02-27 2023-02-27 Light sheet fluorescence microscope

Country Status (1)

Country Link
CN (1) CN220137482U (en)

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