CN220136792U - Sample preparation device - Google Patents
Sample preparation device Download PDFInfo
- Publication number
- CN220136792U CN220136792U CN202321021938.2U CN202321021938U CN220136792U CN 220136792 U CN220136792 U CN 220136792U CN 202321021938 U CN202321021938 U CN 202321021938U CN 220136792 U CN220136792 U CN 220136792U
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- shell
- sample preparation
- wall surface
- preparation device
- fixedly arranged
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- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 239000007791 liquid phase Substances 0.000 claims abstract description 28
- 238000006243 chemical reaction Methods 0.000 claims abstract description 19
- 238000004140 cleaning Methods 0.000 claims abstract description 15
- 230000005540 biological transmission Effects 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 239000012535 impurity Substances 0.000 abstract description 11
- 238000001514 detection method Methods 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 3
- 239000000523 sample Substances 0.000 description 10
- 238000009434 installation Methods 0.000 description 7
- 238000001914 filtration Methods 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 239000011259 mixed solution Substances 0.000 description 4
- 230000010355 oscillation Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000002311 subsequent effect Effects 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 239000004005 microsphere Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Abstract
The utility model discloses a sample preparation device, which has the technical scheme that: the reaction kettle comprises a base, wherein a shell is fixedly arranged on the top surface of the base, a flip plate is hinged to the top surface of the shell, a handle is fixedly arranged on the top surface of the flip plate, and a reaction barrel is fixedly arranged on the inner wall surface of the shell; the cleaning component is arranged on the inner wall surface of the shell and is used for cleaning the liquid phase chip, impurities attached to the surface of the liquid phase chip can be better cleaned out and filtered through the cleaning component, the subsequent detection effect is better, the ultrasonic box is fixedly arranged on the inner wall surface of the shell, the transmission head is fixedly arranged on one side of the inner wall surface of the ultrasonic box, the discharge opening is formed in the inner bottom surface of the ultrasonic box, and tiny organisms attached to the surface of the liquid phase chip can be better removed through the ultrasonic box, so that the liquid phase chip is cleaner, and the next use is not affected.
Description
Technical Field
The utility model relates to the technical field of sample preparation, in particular to a sample preparation device.
Background
The flow type fluorescence, also called suspension array, liquid phase chip, etc. is a multi-index joint diagnosis technology which is developed gradually in recent years, the technology takes fluorescent coding microsphere as a core, integrates various technologies such as flow concentration principle, laser analysis, high-speed digital signal processing, etc., multi-index parallel analysis, can accurately and quantitatively detect 2-500 different biological molecules at most by one tube, has the characteristics of high flux, high sensitivity, parallel detection, etc., and can be used for researches in multiple aspects and fields such as immune analysis, nucleic acid research, enzymology analysis, receptor, ligand identification analysis, etc.
According to publication No.: CN 207908245U's chinese patent, a liquid phase chip sample preparation facilities, including oscillator, water bath reaction dish, vibration bottom plate, pivot, controller, base, the water bath reaction dish sets up the inside at the oscillator, the right side surface of water bath reaction dish is equipped with the controller, the vibration bottom plate sets up the bottom at the oscillator, the lower part of vibration bottom plate is equipped with the vibration pillar, the bottom fixedly connected with centrifuge of vibration pillar, the inside center of centrifuge is equipped with the pivot, the outside of pivot is encircleed and is equipped with the centrifuging tube, centrifuge's bottom is equipped with the carousel, centrifuge's lower part is equipped with power support, the base sets up the bottom at power support, and this liquid phase chip sample preparation facilities simple structure, the function is practical, can satisfy liquid phase chip preparation process needs completely.
However, there are still some disadvantages of the liquid-phase chip sample preparation device described above, such as: the water bath reaction vessel is arranged in the oscillator, a controller is arranged on the right side surface of the water bath reaction vessel, the oscillation bottom plate is arranged at the bottom of the oscillator, the lower part of the oscillation bottom plate is provided with an oscillation support column, the bottom of the oscillation support column is fixedly connected with a centrifugal machine, a plurality of tiny biological impurities can be attached to the surface of the liquid phase chip, and the subsequent detection can be influenced if the liquid phase chip is not cleaned and filtered cleanly.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides a sample preparation device, which solves the problem that a plurality of tiny biological impurities are attached to the surface of a liquid phase chip and can influence the subsequent detection if the liquid phase chip is not cleaned.
The technical aim of the utility model is realized by the following technical scheme:
a sample preparation device comprising: the liquid chip cleaning device comprises a base, wherein a shell is fixedly arranged on the top surface of the base, a flip plate is hinged to the top surface of the shell, a handle is fixedly arranged on the top surface of the flip plate, a reaction barrel is fixedly arranged on the inner wall surface of the shell, and a cleaning component is arranged on the inner wall surface of the shell and used for cleaning the liquid chip.
Through adopting above-mentioned technical scheme, through setting up clean subassembly, through clean subassembly can be better make the impurity that adheres to on liquid phase chip surface wash out and filter away the impurity for subsequent effect that detects is better.
Preferably, the cleaning assembly comprises: the ultrasonic wave case, ultrasonic wave case fixed mounting is in the internal face of shell, interior face one side fixed mounting of ultrasonic wave case has the transmission head, the bin outlet has been seted up to the inside bottom surface of ultrasonic wave case.
Through adopting above-mentioned technical scheme, through setting up the ultrasonic wave case, can be better get rid of the tiny organism attached to above the liquid phase chip through the ultrasonic wave case for the liquid phase chip is cleaner, thereby does not influence the use next time.
Preferably, the cleaning assembly further comprises: the filter cartridge, the outer circular wall of filter cartridge with the interior circular wall fixed cover of bin outlet is established, the outer circular wall fixed mounting of filter cartridge has the control valve, the interior wall one side fixed mounting of shell has electric putter, electric putter telescopic link's one end fixed mounting has the shielding plate.
Through adopting above-mentioned technical scheme, through setting up the cartridge filter, mix the impurity in solution after filtering out through the cartridge filter washing that the cartridge filter can be better to avoid producing the influence to subsequent detection.
Preferably, a water outlet pipe is fixedly arranged on the bottom surface of the reaction barrel, and a water outlet of the water outlet pipe corresponds to a box opening of the ultrasonic box.
Through adopting above-mentioned technical scheme, through setting up the outlet pipe, can discharge the inside of ultrasonic wave case to the inside of liquid phase chip and solution in reaction barrel through the outlet pipe, it is convenient to wash the filtration at the back.
Preferably, the inner bottom surface of the shell is fixedly provided with a mounting block, and the top surface of the mounting block is fixedly provided with a driving motor.
Through adopting above-mentioned technical scheme, through setting up the installation piece, can be better provide holding power for driving motor through the installation piece to make more stable when rotating.
Preferably, one end of the driving motor rotating shaft is fixedly provided with a tray, the top surface of the tray is fixedly provided with a centrifugal machine, and a plurality of centrifugal tubes are movably sleeved in the groove on the top surface of the centrifugal machine.
Through adopting above-mentioned technical scheme, through setting up the tray, can place centrifuge through the tray, the rotation of tray drives centrifuge's rotation to make the more convenient mixed solution of receipt of centrifuging tube, separate it.
In summary, the utility model has the following advantages:
through setting up clean subassembly, the impurity that makes that through clean subassembly can be better adheres to on the liquid phase chip surface washs out and filters away the impurity, make subsequent effect of detection better, through the device, can be better remove to separate and collect for the organism that needs to detect on the liquid phase chip, through setting up the ultrasonic wave case, through the tiny organism of getting rid of that the ultrasonic wave case can be better attached to on the liquid phase chip, make the liquid phase chip cleaner, thereby do not influence the next use, through setting up the cartridge filter, through the filter that the filter cartridge can be better filter out wash back mix the impurity in solution, thereby avoid producing the influence to subsequent detection.
Through setting up the outlet pipe, can discharge the inside of ultrasonic wave case to liquid phase chip and solution inside the reaction bucket through the outlet pipe, for washing the filtration behind and brought convenience, through setting up the installation piece, can be better through the installation piece provide holding power for driving motor to make more stable when rotating, through setting up the tray, can place centrifuge through the tray, the rotation of tray drives centrifuge's rotation, thereby makes the more convenient receipt mixed solution of centrifuging tube, separates it.
Drawings
FIG. 1 is a schematic perspective view of the present utility model;
FIG. 2 is a schematic view of a split construction of the present utility model;
FIG. 3 is a schematic view of the tray structure of the present utility model;
fig. 4 is a schematic view of the structure of the shielding plate of the present utility model.
Reference numerals: 1. a base; 2. a housing; 3. turning over the cover plate; 4. a handle; 5. a reaction barrel; 6. an ultrasonic box; 7. a transmission head; 8. a discharge port; 9. a filter cartridge; 10. a control valve; 11. an electric push rod; 12. a shielding plate; 13. a water outlet pipe; 14. a mounting block; 15. a driving motor; 16. a tray; 17. a centrifuge; 18. centrifuge tube.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1, fig. 2 and fig. 4, a sample preparation device, the on-line screen storage device comprises a base 1, the top surface fixed mounting of base 1 has shell 2, the top surface hinge of shell 2 links and has flip board 3, the top surface fixed mounting of flip board 3 has handle 4, handle 4 is for having the structure and does not do the details here, the inner wall fixed mounting of shell 2 has reaction barrel 5, the inner wall of shell 2 is provided with clean subassembly for clean liquid phase chip, through setting up clean subassembly, the impurity that makes that can be better through clean subassembly is adhered to liquid phase chip surface washs out and filters out the impurity, make the effect of follow-up detection better, clean subassembly still includes cartridge filter 9, cartridge filter 9's outer disc wall and the interior disc wall fixed cover of bin outlet 8 are established, cartridge filter 9's outer disc wall fixed mounting has control valve 10, control valve 10 is for having the structure and does not do nothing here in detail, electric putter 11 is for having the structure here, electric putter 11's one end fixed mounting of telescopic link has shielding plate 12, through setting up cartridge filter 9, can be better through the effect of filtering out of filter cartridge filter 9 and then produces the mixed solution after the follow-up detection.
Referring to fig. 2, 3 and 4, the cleaning assembly includes ultrasonic wave case 6, ultrasonic wave case 6 fixed mounting is at the internal face of shell 2, ultrasonic wave case 6 is not repeated here for having the structure, the inside injection water of ultrasonic wave case 6, internal face one side fixed mounting of ultrasonic wave case 6 has transmission head 7, bin outlet 8 has been seted up to the inside bottom surface of ultrasonic wave case 6, through setting up ultrasonic wave case 6, can be better get rid of the tiny organism attached to the liquid phase chip above through ultrasonic wave case 6, make the liquid phase chip cleaner, thereby do not influence the next use, the inside bottom surface fixed mounting of shell 2 has installation piece 14, the top surface fixed mounting of installation piece 14 has driving motor 15, driving motor 15 is not repeated here for having the structure, through setting up installation piece 14, can be better provide holding power for driving motor 15, thereby make more stable when rotating.
Referring to fig. 2 and 3, a water outlet pipe 13 is fixedly installed on the bottom surface of the reaction barrel 5, a water outlet of the water outlet pipe 13 corresponds to a box opening of the ultrasonic box 6, an adjusting valve is installed on the outer circular wall surface of the water outlet pipe 13, through the arrangement of the water outlet pipe 13, a liquid phase chip and solution in the reaction barrel 5 can be discharged into the ultrasonic box 6 through the water outlet pipe 13, convenience is brought to the cleaning and filtering at the back, a tray 16 is fixedly installed at one end of a rotating shaft of a driving motor 15, a centrifugal machine 17 is fixedly installed on the top surface of the tray 16, the centrifugal machine 17 is not described herein, a plurality of centrifugal tubes 18 are movably sleeved in a groove on the top surface of the centrifugal machine 17, the centrifugal tubes 18 are not described herein for the existing structure, the centrifugal machine 17 can be placed through the tray 16, and the rotation of the tray 16 drives the centrifugal machine 17 to rotate, so that the mixed solution is more conveniently received by the centrifugal tube 18, and the centrifugal machine is separated.
Working principle: referring to fig. 1-4, when in use, a worker opens the cover plate 3 through the handle 4, puts the mixed sample solution and the liquid chip into the reaction barrel 5, after a certain time, opens the valve installed on the water outlet pipe 13, and makes the whole reacted sample flow into the ultrasonic box 6, water is put into the ultrasonic box 6, and ultrasonic waves are emitted through the transmitting head 7, so that the liquid chip is cleaned, after cleaning, the electric push rod 11 is started to drive the shielding plate 12 to move away from the discharge opening 8, so that the solution enters the filter barrel 9 for filtering, then the driving motor 15 is started to drive the tray 16 to rotate, so that each centrifuge tube 18 is aligned with the bottom end outlet of the filter barrel 9, and finally separation work is performed on the liquid chip through the centrifuge 17.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A sample preparation device, comprising:
the reaction kettle comprises a base (1), wherein a shell (2) is fixedly arranged on the top surface of the base (1), a flip plate (3) is hinged to the top surface of the shell (2), a handle (4) is fixedly arranged on the top surface of the flip plate (3), and a reaction barrel (5) is fixedly arranged on the inner wall surface of the shell (2);
and the cleaning component is arranged on the inner wall surface of the shell (2) and is used for cleaning the liquid phase chip.
2. The sample preparation device of claim 1, wherein the cleaning assembly comprises:
the ultrasonic wave case (6), ultrasonic wave case (6) fixed mounting is in the internal face of shell (2), interior face one side fixed mounting of ultrasonic wave case (6) has transmission head (7), bin outlet (8) have been seted up to the inside bottom surface of ultrasonic wave case (6).
3. The sample preparation device of claim 2, wherein the cleaning assembly further comprises:
the filter cartridge (9), the outer circular wall surface of filter cartridge (9) with the interior circular wall surface fixed cover of bin outlet (8) is established, the outer circular wall surface fixed mounting of filter cartridge (9) has control valve (10), the interior wall surface one side fixed mounting of shell (2) has electric putter (11), the one end fixed mounting of electric putter (11) telescopic link has shielding plate (12).
4. The sample preparation device according to claim 1, wherein a water outlet pipe (13) is fixedly arranged on the bottom surface of the reaction barrel (5), and a water outlet of the water outlet pipe (13) corresponds to a tank opening of the ultrasonic tank (6).
5. A sample preparation device according to claim 1, wherein the inner bottom surface of the housing (2) is fixedly provided with a mounting block (14), and the top surface of the mounting block (14) is fixedly provided with a driving motor (15).
6. The sample preparation device according to claim 5, wherein a tray (16) is fixedly mounted at one end of a rotating shaft of the driving motor (15), a centrifugal machine (17) is fixedly mounted on the top surface of the tray (16), and a plurality of centrifugal tubes (18) are movably sleeved in the centrifugal machine (17).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321021938.2U CN220136792U (en) | 2023-05-04 | 2023-05-04 | Sample preparation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321021938.2U CN220136792U (en) | 2023-05-04 | 2023-05-04 | Sample preparation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220136792U true CN220136792U (en) | 2023-12-05 |
Family
ID=88955884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321021938.2U Active CN220136792U (en) | 2023-05-04 | 2023-05-04 | Sample preparation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220136792U (en) |
-
2023
- 2023-05-04 CN CN202321021938.2U patent/CN220136792U/en active Active
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant |