CN220110241U - Experimental rat femoral vein catheter cannula - Google Patents
Experimental rat femoral vein catheter cannula Download PDFInfo
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- CN220110241U CN220110241U CN202320251230.XU CN202320251230U CN220110241U CN 220110241 U CN220110241 U CN 220110241U CN 202320251230 U CN202320251230 U CN 202320251230U CN 220110241 U CN220110241 U CN 220110241U
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- catheter
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- cannula
- segmented
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- 210000003191 femoral vein Anatomy 0.000 title claims abstract description 28
- 241000700159 Rattus Species 0.000 claims description 55
- 229920002635 polyurethane Polymers 0.000 claims description 8
- 239000004814 polyurethane Substances 0.000 claims description 8
- 241000700157 Rattus norvegicus Species 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 abstract description 6
- 241001465754 Metazoa Species 0.000 abstract description 3
- 238000010171 animal model Methods 0.000 description 8
- 210000004204 blood vessel Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000011160 research Methods 0.000 description 3
- 238000009509 drug development Methods 0.000 description 2
- 210000004013 groin Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 241001631457 Cannula Species 0.000 description 1
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000007877 drug screening Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 210000004731 jugular vein Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000011552 rat model Methods 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
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Abstract
The utility model relates to an experimental rat femoral vein catheter cannula, which comprises a catheter and a fixed knot, wherein the catheter comprises four sections of segmented catheters; the fixing joint is arranged between two adjacent segmented catheters and is used for fixing the catheter cannula in the experimental rat body; wherein, all the sectional catheters are sequentially communicated after being connected by the fixed joint; the catheter cannula is fixed in the rat body conveniently by arranging the plurality of fixing joints on the catheter, so that the risk of displacement of the catheter cannula in the rat body is reduced, and the stability and success rate of animal modeling of the operation are improved.
Description
Technical Field
The utility model relates to the technical field of experimental animal surgical consumables, in particular to an experimental rat femoral vein catheter cannula.
Background
The femoral vein catheter catheterization rat model has wide application in the fields of life science, medical research and drug development, and is particularly suitable for research of pharmacokinetics and toxicologic kinetics and drug development and new drug screening. Because the diameter of the femoral vein catheter cannula for making the animal model is much thinner than that of the femoral vein catheter cannula for human, no special femoral vein catheter cannula suitable for rats is available in the prior art. Researchers can only make simple cannulas themselves, for example, find a thinner hose that can be satisfactorily inserted into the femoral vein of a rat, cutting it to a generally suitable length. After the self-made simple catheter cannula is inserted into the femoral vein of a rat, the catheter cannula is difficult to fix in the rat body, if the catheter cannula is displaced in the rat body, an animal model is unstable, so that the whole blood taking and research process is influenced, the whole blood taking service cycle of the femoral vein cannula rat is about 21 days, and the service cycle of the femoral vein cannula rat is improved by about 50% compared with that of the jugular vein cannula rat, and a better model making rat can be provided for researchers.
Disclosure of Invention
Aiming at least one problem in the prior art, the utility model aims to provide the experimental rat femoral vein catheter cannula, and the catheter cannula can be conveniently fixed in a rat body by arranging the fixing knot on the catheter, so that the risk of displacement of the catheter cannula in the rat body is reduced, and the stability of an animal model is improved.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
an experimental rat femoral vein catheter cannula, comprising:
a catheter comprising at least four segments of segmented catheter;
a fixing section arranged between two adjacent segmented catheters and used for fixing the catheter cannula in the experimental rat body;
wherein, all the sectionalized conduits are sequentially communicated after being connected by the fixed joint.
Preferably, the outer diameter of the fixed knot is greater than the outer diameter of the segmented conduit.
Preferably, the segmented catheter has an outer diameter dimension in the range of 1.020mm to 1.025mm and an inner diameter dimension in the range of 0.610 to 0.615mm.
Preferably, the segmented catheter has an outer diameter dimension of 1.020mm and an inner diameter dimension of 0.610mm.
Preferably, the outer diameter size of the fixed joint ranges from 1.650mm to 1.660mm, and the inner diameter size ranges from 0.760mm to 0.770mm.
Preferably, the outer diameter size of the fixed joint is 1.650mm, and the inner diameter size range is 0.760mm.
Preferably, the duct comprises four sections of segmented duct, namely a first section of duct, a second section of duct, a third section of duct and a tail section of duct.
Preferably, the first section of the catheter is 34mm in length, the second section of the catheter is 23.5mm in length, the third section of the catheter is 83.5mm in length, and the tail section of the catheter is 96mm in length.
Preferably, the segmented catheter and the fixed knot are both transparent tubes.
Preferably, the segmented catheter and the fixed knot are both transparent tubes made of polyurethane.
Due to the adoption of the technical scheme, the utility model has the following advantages:
1. according to the experimental rat femoral vein catheter cannula provided by the utility model, the catheter cannula can be conveniently fixed in a rat body by arranging the plurality of fixing joints on the catheter, so that the risk of displacement of the catheter cannula in the rat body is reduced, and the stability of an animal model is improved.
2. The experimental rat femoral vein catheter cannula provided by the utility model has three fixing sections of four sections of segmented catheters, so that the least effective number of the catheter cannula can be fixed in the experimental rat, and the effective fixation of the catheter is ensured.
3. The experimental rat femoral vein catheter provided by the utility model has the advantages that the polyurethane catheter is not easy to damage blood vessels, has good adhesion with the inner wall of the blood vessels, and is not easy to leak blood.
Drawings
Fig. 1 is a schematic view of a femoral vein catheter for experimental rats according to an embodiment of the present utility model.
The reference numerals in the drawings:
1 is a first section of conduit, 2 is a second section of conduit, 3 is a third section of conduit, 4 is a tail section of conduit, 5 is a first fixed joint, 6 is a second fixed joint, and 7 is a third fixed joint.
Detailed Description
In order to make the objects, technical solutions and advantages of the present utility model more apparent, the technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings. It will be apparent that the described embodiments are some, but not all, embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In the description of the present utility model, it should be noted that the azimuth or positional relationship indicated by the terms "upper", "lower", "front", "rear", etc. are based on the azimuth or positional relationship shown in the drawings, and are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the system or element referred to must have a specific azimuth, be configured and operated in a specific azimuth, and thus should not be construed as limiting the present utility model.
In the description of the present utility model, it should be noted that, unless explicitly stated and limited otherwise, the terms "mounted," "disposed," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.
According to the experimental rat femoral vein catheter cannula provided by the utility model, the catheter cannula can be conveniently fixed in a rat body by arranging the fixing knot on the catheter, so that the risk of displacement of the catheter cannula in the rat body is reduced, and the stability of an animal model is improved.
Hereinafter, embodiments of the present utility model will be described in detail with reference to the accompanying drawings.
Examples
Referring to fig. 1, the experimental rat femoral vein catheter provided in this embodiment includes a catheter and a fixing section, the catheter includes at least four sections of segmented catheters; the fixing joint is arranged between two adjacent segmented catheters and is used for fixing the catheter cannula in the experimental rat body; wherein, all the sectional catheters are sequentially communicated after being connected by the fixed joint.
In the specific application, the guide pipe and the fixed joint are transparent round pipes, and the guide pipe is a hose. The guide pipe comprises four sections of segmented guide pipes, namely a first section of guide pipe 1, a second section of guide pipe 2, a third section of guide pipe 3 and a tail section of guide pipe 4; the fixed knot includes three, respectively first fixed knot 5, second fixed knot 6 and third fixed knot 7, and first fixed knot 5 sets up between first section pipe 1 and second section pipe 2, and second fixed knot 6 sets up between second section pipe 2 and third section pipe 3, and third fixed knot 7 sets up between third section pipe 3 and tailstock pipe 4. The first section of conduit 1, the second section of conduit 2, the third section of conduit 3, the tail section of conduit 4, the first fixed joint 5, the second fixed joint 6 and the third fixed joint 7 form a transparent pipe with communicated inside. After the catheter cannula is inserted into the femoral vein of the experimental rat, the catheter cannula can be fixed in the rat body through the fixing joint, so that the risk of displacement of the catheter cannula in the rat body is reduced, and the stability and success rate of the operation animal modeling are improved. The segmented conduit and the fixed joint can be an integrated pipe which is formed by one-step molding.
In this embodiment, the outer diameter of the fixed knot is larger than the outer diameter of the segmented catheter, and the fixed knot is easier to fix on the experimental rat.
In this embodiment, the segmented catheter has an outer diameter dimension in the range of 1.020mm to 1.025mm and an inner diameter dimension in the range of 0.610 to 0.615mm.
In a specific application, the outer diameter of the segmented catheter is 1.020mm and the inner diameter is 0.610mm. The inner diameter and the outer diameter of the segmented catheter can ensure the compatibility and the safety of the intravenous catheter cannula of the experimental rat to the greatest extent, and also ensure the convenience of use of scientific researchers, and simultaneously, the tail end of the segmented catheter is conveniently matched with the connection of an external auxiliary device.
In this embodiment, the fixed joint has an outer diameter in the range of 1.650mm to 1.660mm and an inner diameter in the range of 0.760mm to 0.770mm.
In a specific application, the outer diameter size of the fixed joint is 1.650mm, and the inner diameter size range is 0.760mm. The fixed joint and the segmented catheter are made of the same material and can be made of polyurethane, so that the compatibility of the polyurethane catheter to experimental rats is good, the polyurethane catheter is not easy to damage blood vessels, the adhesion between the polyurethane catheter and the inner wall of the blood vessels is good, and blood leakage is not easy to occur; the fixed knot and the pipe material are compatible, and fixed knot external diameter slightly is greater than the external diameter of segmentation pipe, with fixed knot fixed on the experimental animal on one's body back, can not cause whole pipe intubate to slide, and fixed knot is convenient for operation suture and is fixed in the animal, has fully played the fixed effect.
In this example, the first conduit length was 34mm, the second conduit length was 23.5mm, the third conduit length was 83.5mm, and the last conduit length was 96mm. The length of the first fixed knot 5 is 2.5mm, the length of the second fixed knot 6 is 2.5mm, and the length of the third fixed knot 7 is 3.0mm.
In some applications, the length of the first segment of the catheter can be customized according to the body length of the experimental rat, namely, the length of the experimental rat, and is generally customized according to the body length of an adult rat, namely, 15-20 cm. The lengths of the two-section guide tube and the three-section guide tube can be customized by combining the body length of the rat and the distance between the groin and the back, so that the guide tube can extend from the groin of the rat to the back, and the guide tube can not be scratched by the rat when the guide tube is penetrated out of the back, and the subsequent experimental operation is convenient.
In this embodiment, the segmented conduit and the fixed joint are transparent tubes made of polyurethane, and the transparent tubes are hoses. The transparent tube can be used for conveniently observing the liquid flow condition in the tube.
When the experimental rat femoral vein catheter is used for manufacturing a rat femoral vein catheter model, a small incision is made in a blood vessel, the first section catheter 1 is inserted into the rat femoral vein blood vessel until a first fixing knot 5 between the first section catheter 1 and the second section catheter 2 is contacted with the blood vessel incision, and the femoral vein catheter is sutured and fixed with the first fixing knot 5 by using a surgical wire. Using a trocar to puncture from the back incision to the inguinal incision, pulling out the needle core, introducing the catheter cannula into the trocar through the inguinal incision, and leading out from the back incision; the trocar was removed from the experimental rat and the second fixation section 6 between the two-section catheter 2 and the three-section catheter 3 was sutured and fixed to the abdominal wall muscle with surgical threads. The inguinal incision is closed and the third fixation knot 7 between the three-section catheter 3 and the tail section catheter 4 is fixed to the muscle of the dorsal incision with surgical suture. The tail section catheter 4 is placed subcutaneously in the back and the back incision is closed. And (5) completing the rat femoral vein cannula model. The catheter cannula of the embodiment can conveniently fix the catheter cannula in the rat body by arranging the plurality of fixing joints on the catheter, so that the risk of displacement of the catheter cannula in the rat body is reduced, and the stability of an animal model is improved.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and are not limiting; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present utility model.
Claims (8)
1. An experimental rat femoral vein catheter cannula, comprising:
a catheter comprising at least four segments of segmented catheter;
a fixing section arranged between two adjacent segmented catheters and used for fixing the catheter cannula in the experimental rat body;
wherein all the segmented catheters are sequentially communicated after being connected through the fixed joint;
the guide pipe comprises four sections of segmented guide pipes, namely a first section of guide pipe, a second section of guide pipe, a third section of guide pipe and a tail section of guide pipe;
the length of the first section of conduit is 34mm, the length of the second section of conduit is 23.5mm, the length of the third section of conduit is 83.5mm, and the length of the tail section of conduit is 96mm.
2. The laboratory rat femoral venous catheter cannula of claim 1, wherein an outer diameter of the fixation section is greater than an outer diameter of the segmented catheter.
3. The experimental rat femoral catheter cannula of claim 1, wherein the segmented catheter has an outer diameter dimension ranging from 1.020mm to 1.025mm and an inner diameter dimension ranging from 0.610 to 0.615mm.
4. The experimental rat femoral vein catheter cannula of claim 3, wherein said segmented catheter has an outer diameter dimension of 1.020mm and an inner diameter dimension of 0.610mm.
5. The experimental rat femoral catheter cannula of claim 1, wherein the fixed knot has an outer diameter dimension ranging from 1.650mm to 1.660mm and an inner diameter dimension ranging from 0.760mm to 0.770mm.
6. The experimental rat femoral catheter cannula of claim 5, wherein the fixed knot has an outer diameter dimension of 1.650mm and an inner diameter dimension ranging from 0.760mm.
7. The experimental rat femoral catheter cannula of claim 1, wherein the segmented catheter and the fixation section are both transparent tubes.
8. The experimental rat femoral catheter cannula of claim 7, wherein the segmented catheter and the fixation section are both transparent tubes made of polyurethane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320251230.XU CN220110241U (en) | 2023-02-07 | 2023-02-07 | Experimental rat femoral vein catheter cannula |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320251230.XU CN220110241U (en) | 2023-02-07 | 2023-02-07 | Experimental rat femoral vein catheter cannula |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220110241U true CN220110241U (en) | 2023-12-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320251230.XU Active CN220110241U (en) | 2023-02-07 | 2023-02-07 | Experimental rat femoral vein catheter cannula |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220110241U (en) |
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2023
- 2023-02-07 CN CN202320251230.XU patent/CN220110241U/en active Active
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