CN220056884U - Automatic cover device of PCR board - Google Patents
Automatic cover device of PCR board Download PDFInfo
- Publication number
- CN220056884U CN220056884U CN202321645886.6U CN202321645886U CN220056884U CN 220056884 U CN220056884 U CN 220056884U CN 202321645886 U CN202321645886 U CN 202321645886U CN 220056884 U CN220056884 U CN 220056884U
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- Prior art keywords
- pcr
- pcr plate
- frame
- cap
- cover
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- 210000004907 gland Anatomy 0.000 claims description 32
- 230000001360 synchronised effect Effects 0.000 claims description 13
- 238000009434 installation Methods 0.000 claims description 4
- 239000011159 matrix material Substances 0.000 claims description 2
- 238000007789 sealing Methods 0.000 abstract description 14
- 238000003752 polymerase chain reaction Methods 0.000 abstract description 8
- 239000012528 membrane Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 230000003321 amplification Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000003199 nucleic acid amplification method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000004484 Briquette Substances 0.000 description 1
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 108010006785 Taq Polymerase Proteins 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model relates to the field of capping devices, in particular to an automatic capping device for a PCR (polymerase chain reaction) plate, which is characterized by comprising a base component and a cap frame arranged on the base component, wherein the cap frame is used for placing a pipe cap, a positioning device is arranged on the base component, the PCR plate to be capped is placed in the positioning device and used for positioning the position between the cap frame and the PCR plate, the cap frame is provided with a capping component used for pressing the pipe cap on the PCR plate, the capping component moves on the base component through a driving device, the pipe cap is positioned through the cap frame, and the capping device is controlled to perform capping, so that the sealing of the PCR plate is realized, the degree of automation is higher, and the working efficiency is effectively improved.
Description
Technical Field
The utility model relates to a capping device, in particular to an automatic capping device for a PCR plate.
Background
The PCR plate is mainly used as a carrier of a primer, taq DNA polymerase, dNTP, template nucleic acid, mg, buffer solution and the like which participate in amplification reaction in a polymerase chain reaction (Polymerase Chain Reaction, PCR), the hole on the PCR plate needs to be sealed before amplification, the sealing membrane is used for sealing at present, such as a pressure sensitive membrane, a self-adhesive membrane, a heat sealing membrane, an aluminum membrane and the like, the whole roll or the cut single membrane is generally adopted, and the existing sealing mechanism has large volume; the whole roll of film is difficult to replace; the sealing effect is unstable, and a few holes are easy to be sealed poorly; during amplification, the pressure in the hole of the PCR plate can be increased by heating, the sealing of part of the hole is poor, the sealing part can be possibly opened by the pressure, and the leakage and diffusion of the content can generate pollution.
Disclosure of Invention
The utility model aims to solve the technical problems that: the sealing effect on the hole on the PCR plate is not good.
In order to solve the technical problems, the utility model adopts the following technical scheme:
firstly, provide an automatic lid device of PCR board, its characterized in that includes the base subassembly, and set up lid frame on the base subassembly, be used for placing the tube cap on the lid frame, set up positioner on the base subassembly, place the PCR board of waiting to cover in the positioner for the position between lid frame and the PCR board, set up the gland subassembly on the lid frame, be used for pressing the tube cap on the PCR board, the gland subassembly is through drive arrangement removal on the base subassembly.
Further, positioner includes the rack, be equipped with the rack on the base subassembly for place and fix a position the PCR board, set up first setting element on the rack, set up the second setting element with first setting element looks adaptation on the lid frame.
Further, the first locating piece and the second locating piece are magnets which are attracted to each other, a plurality of first locating pieces distributed in a matrix are arranged on the top surface of the placement frame, and the second locating pieces are arranged at positions of the cover frame corresponding to the first locating pieces.
Further, the gland assembly comprises a gland housing, wherein a pressing block is arranged in the gland housing and is used for pressing the pipe cover on the PCR plate.
Further, a first motor is arranged in the gland casing, a fixing piece is arranged on the first motor, a pressing block is connected to the fixing piece in a sliding mode through a guide rail, a rack is arranged on the pressing block, and a gear meshed with the rack is sleeved on an output shaft of the first motor.
Further, the base assembly comprises a base shell, a driving device is arranged in the base shell, and a mounting edge connected with the driving assembly is arranged on the gland shell.
Further, the driving device comprises a second motor, the base shell is provided with a driven wheel, the output shaft of the second motor is provided with a synchronous belt connected with the driven wheel, and the installation edge is connected with the synchronous belt.
Further, a slide block is arranged at the bottom surface of the base shell corresponding to the synchronous belt, and a pressing plate is arranged on the slide block and used for pressing the synchronous belt on the slide block, and the installation edge is installed on the pressing plate.
Further, a first position sensor is arranged on the sliding block and used for detecting the position of the gland casing, and a second position sensor is arranged in the gland casing and used for detecting the position of the pressing block.
Further, a plurality of strip-shaped through holes are formed in the cover frame at positions corresponding to the pipe covers and are used for accommodating a plurality of pipe covers, and a plurality of penetrating grooves are formed between the adjacent through holes.
The utility model has the following beneficial effects:
1. according to the utility model, the second motor is used for driving the gland assembly to move to a preset position, and then the pipe cover is pressed on the PCR plate through the first motor for driving the pressing block, so that the sealing of the PCR plate is realized, the automation degree is higher, and the efficiency is improved.
2. The pressing blocks with different shapes can be designed according to actual conditions in the using process so as to press the tube covers with different shapes on the PCR plate, and meanwhile, the positioning device is used for locking the position relationship between the cover frame and the PCR plate, so that the tube covers placed on the cover frame can be accurately aligned with holes on the PCR plate, the occurrence of cover leakage is reduced, and the follow-up process is convenient;
3. because the sealing performance of the pipe cover is good, the occurrence of air leakage can be avoided in the using process of the PCR plate, thereby improving the working quality.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic perspective view of the present embodiment;
FIG. 2 is a schematic view showing the internal structure of the base assembly according to the present embodiment;
fig. 3 is a schematic structural view of the rack according to the present embodiment;
fig. 4 is a first structural schematic diagram of the cover frame of the present embodiment;
FIG. 5 is a second mechanism diagram of the cover rack of the present embodiment;
fig. 6 is a schematic view of the gland housing of the present embodiment;
FIG. 7 is a schematic view showing the internal structure of the gland assembly of the present embodiment;
fig. 8 is an installation schematic diagram of the briquette of the present embodiment.
Detailed Description
The utility model will be better explained by the following detailed description of the embodiments with reference to the drawings.
It should be noted that all the directional indicators in the embodiments of the present utility model are only used to explain the relative positional relationship, movement conditions, etc. between the components in a specific posture, and if the specific posture is changed, the directional indicators are correspondingly changed.
Furthermore, descriptions such as those referred to as "first," "second," and the like, are provided for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implying an order of magnitude of the indicated technical features in the present disclosure. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present utility model, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.
In the present utility model, unless specifically stated and limited otherwise, the terms "connected," "affixed," and the like are to be construed broadly, and for example, "affixed" may be a fixed connection, a removable connection, or an integral body; can be mechanically or electrically connected; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.
The present utility model provides an automatic cap device for a PCR plate, as shown in fig. 1 and 3, comprising a base assembly 1 and a cap assembly 2, wherein the cap assembly 2 is mounted on the base assembly 1 and enables the cap assembly 2 to slide on the base assembly 1, wherein a cap frame 105 is provided between the base assembly 1 and the cap assembly 2, in this embodiment, two cap frames 105 are provided, the cap frames 105 are used for placing a tube cap 107, the PCR plate 103 for cap is placed under the cap frames 105, the cap assembly 2 is moved to the upper side of the cap frames 105, and the tube cap 107 placed on the cap frames 105 is pressed onto the PCR plate 103, thereby sealing the hole on the PCR plate 103.
In this embodiment, in order to drive the gland assembly 2 to move, as shown in fig. 2, the base assembly 1 includes a base housing 101, a second motor 112 and a driven wheel 114 are installed in the base housing 101, the driven wheel 114 is connected with the second motor 112 through a synchronous belt 113, wherein the second motor 112 can drive the synchronous belt 113 to move under the assistance of the driven wheel 114 when driving, and the gland assembly 2 can be driven to move by installing the gland assembly 2 on the synchronous belt 113.
Wherein in order to drive gland subassembly 2 that can be more steady and remove, slider 116 is installed to the position that corresponds hold-in range 113 in the base shell 101, slider 116 can slide in the base shell 101, install clamp plate 115 on the slider 116, wherein clamp plate 115 compresses tightly hold-in range 113 on slider 116, so when hold-in range 113 removes, just can drive slider 116 also synchronous motion, install gland subassembly 2 on clamp plate 115 and can steady operation, wherein be provided with first position sensor on slider 116, first position sensor is used for detecting gland subassembly 2's position, guarantee that gland subassembly can be smooth with tube cap 107 pressure on PCR board 103.
As shown in fig. 3 and 5, in order to ensure that the tube cover 107 is aligned with the hole in the PCR plate 103 when the gland is performed, a rack 102 is mounted on the base housing 101, and the PCR plates 103 are placed in the rack 102, in this embodiment, two PCR plates 103 are placed in the rack 102.
Firstly, the PCR plate 103 placed in the placement frame 102 is positioned, the internal size of the placement frame 102 and the size of the PCR plate 103 can be designed to be matched with each other, so that when the PCR plate 103 is placed in, the PCR plate 103 is automatically positioned at the moment, after the PCR plate 103 is positioned, the cover frame 105 is placed on the placement frame 102, wherein in order to ensure the position correspondence between the cover frame 105 and the PCR plate 103, a first positioning piece 104 is arranged on the top surface of the placement frame 102, and a second positioning piece 108 is arranged on the cover frame 105, wherein the first positioning piece 104 and the second positioning piece 108 are matched with each other, so that the position of the cover frame 105 is determined.
In this embodiment, the first positioning member 104 and the second positioning member 108 are magnets that attract each other, so when the cover frame 105 is placed on the placement frame 102, the first positioning member 104 and the second positioning member 108 can be attached under the action of magnetic force, so that the cover frame 105 is located at a preset position, the tube cover 107 placed on the cover frame 105 is aligned with the corresponding PCR plate 103, the tube cover 107 can successfully seal the PCR plate 103, and meanwhile, positioning of the cover frame 105 can be achieved through hole pin matching.
As shown in fig. 4, in this embodiment, the cover frame 105 is provided with a long through hole 106 for placing a strip-shaped tube cover 107, the tube cover 107 is placed in the through hole 106, then the gland assembly 2 moves to the position of the tube cover 107, and then the tube cover 107 passes through the through hole 106 and is pressed onto the PCR plate 103 to realize the sealing of the PCR plate 103, wherein some tube covers 107 are connected through a plurality of individual tube covers 107, and are made of materials easy to break off, when the tube covers 107 pass through the through hole, the connected materials break at this time to enable the individual tube covers 107 to be sealed on the PCR plate 103, so that a plurality of through grooves 109 are formed between the corresponding through holes 106, and the materials for connecting the tube covers 107 are located in the grooves 109, so that the connection materials can be positioned, and the connection materials break easily, and the gland is convenient to perform.
As shown in fig. 6, the gland assembly 2 includes a gland housing 201, where a mounting edge 202 is disposed at a position of the gland housing 201 corresponding to a pressing plate 115, where the mounting edge 202 may be mounted on the pressing plate 115 through a bolt, so that the gland housing 201 may be smoothly and stably driven to move, and for stability, two symmetrical synchronous belts 113 and two mounting edges 202 may be disposed to drive the gland housing 201 to move.
As shown in fig. 7 and 8, in order to stably press the tube cover 107 onto the PCR plate 103, a first motor 203 is disposed in the gland housing 201, a fixing member 204 is mounted on the first motor 203, a pressing block 206 is slidably connected to the fixing member 204, the fixing of the tube cover 107 can be completed by moving the pressing block 206 up and down along the fixing member 204, in this embodiment, the fixing member 204 and the pressing block 206 are slidably connected through a sliding rail 205, so that the pressing block 206 can stably move up and down, a rack 207 is fixedly mounted on a side surface of the pressing block 206 opposite to the fixing member 204, a gear 208 is sleeved on an output shaft of the first motor 203, the gear 208 is meshed with the rack 207, and when the first motor 203 drives the gear 207 to rotate, the rack 207 can be toggled, that is, the pressing block 206 is driven to move. Wherein a second position sensor is provided within the gland housing 201 for detecting the position of the pressure block 206.
When the embodiment is used, firstly, the second motor 112 operates to drive the gland assembly 2 to move to the position of the tube cover 107, and then the first motor 203 operates to drive the pressing block 206 to move downwards, so that the tube cover 107 passes through the through hole 106 and presses on the PCR plate 103, thereby realizing the sealing of the PCR plate 103.
It should be understood that the above description of the specific embodiments of the present utility model is only for illustrating the technical route and features of the present utility model, and is for enabling those skilled in the art to understand the present utility model and implement it accordingly, but the present utility model is not limited to the above-described specific embodiments. All changes or modifications that come within the scope of the appended claims are intended to be embraced therein.
Claims (10)
1. The utility model provides an automatic lid device of PCR board, its characterized in that includes base subassembly (1), and sets up lid frame (105) on base subassembly (1), be used for placing tube cap (107) on lid frame (105), set up positioner on base subassembly (1), place in the positioner treat lid PCR board (103) for the position between lid frame (105) and PCR board (103), set up gland subassembly (2) on lid frame (105) for press tube cap (107) on PCR board (103), gland subassembly (2) are through drive arrangement removal on base subassembly (1).
2. The automatic cover device of a PCR plate according to claim 1, wherein the positioning device comprises a placement frame (102), the placement frame (102) is arranged on the base assembly (1) and is used for placing and positioning the PCR plate (103), a first positioning piece (104) is arranged on the placement frame (102), and a second positioning piece (108) matched with the first positioning piece (104) is arranged on the cover frame (105).
3. The automatic cover device for the PCR plate according to claim 2, wherein the first positioning members (104) and the second positioning members (108) are magnets attracted to each other, a plurality of first positioning members (104) distributed in a matrix are arranged on the top surface of the placement frame (102), and the second positioning members (108) are arranged at positions of the cover frame (105) corresponding to the first positioning members (104).
4. An automatic cap device for a PCR plate according to claim 1, wherein the cap assembly (2) comprises a cap housing (201), and wherein a press block (206) is provided in the cap housing (201) for pressing the tube cap (107) onto the PCR plate (103).
5. The automatic cover covering device for the PCR plate according to claim 4, wherein a first motor (203) is arranged in the cover covering shell (201), a fixing piece (204) is arranged on the first motor (203), a pressing block (206) is connected on the fixing piece (204) in a sliding mode through a guide rail (205), a rack (207) is arranged on the pressing block (206), and a gear (208) meshed with the rack (207) is sleeved on an output shaft of the first motor (203).
6. The automatic cover closing device of a PCR plate according to claim 4, wherein the base assembly (1) comprises a base housing (101), a driving device is arranged in the base housing (101), and a mounting edge (202) connected with the driving assembly is arranged on the cover closing housing (201).
7. The automatic cover closing device for a PCR plate according to claim 6, wherein the driving device comprises a second motor (112), the base housing (101) is provided with a driven wheel (114), the output shaft of the second motor (112) is provided with a synchronous belt (113) connected with the driven wheel (114), and the mounting edge (202) is connected with the synchronous belt (113).
8. The automatic cover covering device for the PCR plate according to claim 7, wherein a slide block (116) is arranged on the bottom surface of the base housing (101) at a position corresponding to the synchronous belt, a pressing plate (115) is arranged on the slide block (116) and used for pressing the synchronous belt (113) on the slide block (116), and the installation edge (202) is installed on the pressing plate (115).
9. The automatic cover closing device of a PCR plate according to claim 8, wherein a first position sensor is provided on the slider (116) for detecting the position of the cover closing housing (201), and a second position sensor is provided in the cover closing housing (201) for detecting the position of the pressing block (206).
10. The automatic cover device for a PCR plate according to any one of claims 1 to 9, wherein a plurality of elongated through holes (106) are formed in the cover frame (105) at positions corresponding to the tube covers (107) for accommodating the tube covers (107), and a plurality of through grooves (109) are formed between adjacent through holes (106).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321645886.6U CN220056884U (en) | 2023-06-27 | 2023-06-27 | Automatic cover device of PCR board |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321645886.6U CN220056884U (en) | 2023-06-27 | 2023-06-27 | Automatic cover device of PCR board |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220056884U true CN220056884U (en) | 2023-11-21 |
Family
ID=88768099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321645886.6U Active CN220056884U (en) | 2023-06-27 | 2023-06-27 | Automatic cover device of PCR board |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220056884U (en) |
-
2023
- 2023-06-27 CN CN202321645886.6U patent/CN220056884U/en active Active
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant |