CN219940875U

CN219940875U - Fixing device for mouse heat shock experiments

Info

Publication number: CN219940875U
Application number: CN202321273419.5U
Authority: CN
Inventors: 徐静; 王晨琛
Original assignee: Shanghai Ruijikang Biopharmaceutical Co ltd
Current assignee: Shanghai Ruijikang Biopharmaceutical Co ltd
Priority date: 2023-05-24
Filing date: 2023-05-24
Publication date: 2023-11-03
Anticipated expiration: 2033-05-24

Abstract

The utility model provides a fixing device for a mouse heat shock experiment, which comprises: the fixing plate is provided with a plurality of openings, and the binding belt can pass through the openings to bind and fix the mice; the fixing bracket comprises a base, a connecting part and a connecting pipe for connecting the base and the connecting part, wherein the connecting pipe is a flexible deformable pipe, and the connecting part is detachably connected with the fixing plate; when the connecting part is connected with the fixed plate, the space position of the fixed plate can be adjusted by changing the shape of the connecting pipe. The utility model has the advantages that the space position of the mouse can be flexibly changed by arranging the porous fixing plate and the fixing bracket with the flexible and deformable connecting pipe, thereby ensuring the water bath heat shock of the specific part (including testes) of the mouse, being applicable to the mice with different ages and different body types, being more convenient for scientific researchers to observe the mouse and ensuring the mice not to die suddenly in the experimental process. The device simple structure, the equipment of being convenient for, the practicality is strong.

Description

Fixing device for mouse heat shock experiments

Technical Field

The utility model relates to equipment for biological experiments, in particular to a fixing device for a mouse heat shock experiment.

Background

In the field of biological research, heat shock is a common experiment on a specific part of a mouse, and hot water bath is needed to be performed on the specific part of the mouse in the experiment process, but other parts cannot be subjected to hot water bath at the same time. In a mouse testis heat shock experiment, testes in high temperature heat shock for a long time are known to induce apoptosis of spermatogenic cells, influence normal development of a mouse reproductive system and cause sterility in severe cases, so that the influence of heat shock of a high temperature water bath on the mouse reproductive system needs to be explored through the mouse testis heat shock experiment. In the experimental process, besides the thermal stimulation to the testes of the mice, the states of the mice need to be kept and observed, so that death caused by unsmooth breathing of the mice due to gunpowder or water bath is avoided, and the effectiveness and reliability of experimental results are influenced. The existing mouse fixing device is a non-transparent product, the whole body of the mouse is wrapped to control the activity of the mouse, scientific researchers cannot conveniently monitor the life state of the mouse in real time, and the existing mouse fixing device generally does not have the function of enabling the mouse to vertically enter water, cannot change the spatial position of the mouse, cannot meet the experimental requirement that a specific part (such as testis) of the mouse enters water bath heat shock, and other parts are at room temperature.

Disclosure of Invention

Aiming at the defects in the prior art, the utility model provides the fixing device for the mouse heat shock experiment, which not only can carry out the heat shock experiment of the hot water bath on the specific part (such as testis) of the mouse in the experiment process, but also is convenient for scientific researchers to monitor the life state of the mouse in real time.

The utility model provides a fixing device for a mouse heat shock experiment, which comprises: the fixing plate is provided with a plurality of openings, and the binding belt can pass through the openings to bind and fix the mice; the fixing bracket comprises a base, a connecting part and a connecting pipe for connecting the base and the connecting part, wherein the connecting pipe is a flexible deformable pipe, and the connecting part is detachably connected with the fixing plate; when the connecting part is connected with the fixing plate, the space position of the fixing plate can be adjusted by changing the shape of the connecting pipe.

Preferably, the fixing plate is made of transparent materials.

Preferably, the plurality of holes are a plurality of round holes and/or a plurality of long holes uniformly arrayed on the fixing plate.

Preferably, the connecting part is a polygonal structure or a clamping hook.

Preferably, the connecting pipe is a coiled pipe or a corrugated pipe.

The utility model has the advantages that the space position of the mouse can be flexibly changed by arranging the porous fixing plate and the fixing bracket with the flexible and deformable connecting pipe, thereby ensuring the water bath heat shock of the specific part (including testes) of the mouse, being applicable to the mice with different ages and different body types, being more convenient for scientific researchers to observe the mouse and ensuring the mice not to die suddenly in the experimental process. The device simple structure, the equipment of being convenient for, the practicality is strong.

Drawings

FIG. 1 is a schematic view of the operation of a fixing plate;

fig. 2 is a schematic structural view of the fixing bracket.

Description of element numbers:

1. fixing plate

11. Round hole

12. Long hole

2. A mouse

3. Ribbon

4. Binding belt

5. Fixing support

51. Base seat

52. Connecting pipe

53. Connecting part

Detailed Description

The following describes the embodiments of the present utility model in further detail with reference to the accompanying drawings. These embodiments are merely illustrative of the present utility model and are not intended to be limiting.

In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

Furthermore, in the description of the present utility model, unless otherwise indicated, the meaning of "a plurality" is two or more.

The utility model provides a fixing device for a mouse heat shock experiment, which comprises a fixing plate 1 and a fixing bracket 5. As shown in fig. 1, the fixing plate 1 is provided with a plurality of holes, and the binding belt 3 and the binding belt 4 can pass through the holes to bind and fix the mice 2. Specifically, the fixing plate 1 is made of transparent materials, such as a transparent acrylic plate, has long service life and good wear resistance, and is convenient for scientific researchers to observe the state of the mouse 2 and the fixing mode thereof. The holes are a plurality of round holes 11 and a plurality of long holes 12 which are uniformly arrayed on the fixed plate 1, the binding belt 3 can pass through the round holes 11 with the diameter of 0.5cm to bind the limbs of the mice 2, and the binding belt 4 can pass through the long holes 12 with the length of 2cm to bind the trunk of the mice 2. The loose binding of the mouse 2 can be completed by directly cutting the binding belt 3 and the binding belt 4. The porous fixing plate 1 can adapt to binding positions required by mice 2 of different ages and different sizes, and the shape, the size and the position of the opening can be changed by a person skilled in the art according to requirements, so that the mice 2 can be conveniently fixed.

As shown in fig. 2, the fixing bracket 5 includes a base 51, a connection portion 53, and a connection pipe 52 for connecting the base 51 and the connection portion 53, the base 51 providing a bottom support, the connection pipe 52 being a flexible deformable pipe, the connection portion 53 being detachably connected with the fixing plate 1. When the connection portion 53 is connected to the fixing plate 1, the spatial position of the fixing plate 1 can be adjusted by changing the shape of the connection pipe 52. The connection pipe 52 is a coiled pipe or a corrugated pipe made of metal, which has good flexibility and support, and can suspend the connection part 53 and the fixing plate 1. The connection portion 53 may be made of plastic, and its structural form is not limited and may be a polygonal structure or a hook. Each corner of the polygonal structure (e.g., a cross-shaped plate or a pentagonal plate) is fixedly connected with the opening by a tie, or the connecting portion 53 is connected to the fixing plate 1 by directly clamping the hook in the opening.

The using method of the fixing device comprises the following steps:

s1, as shown in FIG. 1, after the anesthesia of the mouse 2, the thoracic cavity part of the mouse 2 is fixed by a strap 4 through the long hole 12, the four limbs of the mouse 2 are fixed by a strap 3 through the round hole 11, and the mouse 2 is fixed on the fixing plate 1.

S2, as shown in fig. 2, the connecting portion 53 is connected to the opening in the fixing plate 1, so that the relative position between the connecting portion 53 and the fixing plate 1 is fixed.

S3, placing the base 51 on a laboratory bench, placing the fixing plate 1 beside the water bath kettle, manually adjusting the connecting pipe 52 to enable the mouse 2 to vertically enter water, immersing testis parts and lower limbs of the mouse in the water, and keeping other parts in a dry state. The status of mouse 2 was observed at fixed intervals to avoid death of mouse 2.

The foregoing is merely a preferred embodiment of the present utility model, and it should be noted that modifications and substitutions can be made by those skilled in the art without departing from the technical principles of the present utility model, and these modifications and substitutions should also be considered as being within the scope of the present utility model.

Claims

1. The utility model provides a fixing device for mouse heat shock experiments which characterized in that includes:

the fixing plate is provided with a plurality of openings, and the binding belt can pass through the openings to bind and fix the mice;

the fixing bracket comprises a base, a connecting part and a connecting pipe for connecting the base and the connecting part, wherein the connecting pipe is a flexible deformable pipe, and the connecting part is detachably connected with the fixing plate;

when the connecting part is connected with the fixing plate, the space position of the fixing plate can be adjusted by changing the shape of the connecting pipe.

2. The fixing device for a heat shock test of a mouse according to claim 1, wherein the fixing plate is made of transparent material.

3. The fixing device for a heat shock test of a mouse according to claim 1, wherein the plurality of holes are a plurality of round holes and/or a plurality of long holes uniformly arrayed on the fixing plate.

4. The fixing device for a heat shock test of a mouse according to claim 1, wherein the connecting portion is a polygonal structure or a hook.

5. The fixing device for a heat shock test of a mouse according to claim 1, wherein the connection tube is a coil tube or a bellows tube.