CN219935369U - Liquid reservoir, combined sample detection structure and sampling detection device - Google Patents

Abstract

The utility model discloses a liquid reservoir, a combined sample detection structure and a sampling detection device, wherein the combined sample detection structure comprises a kit, a cavity capable of accommodating detection test paper is arranged in the kit, a sampling window is formed in the top of the kit, and the detection test paper is arranged below the sampling window; the liquid storage device comprises a liquid storage device, a reagent box and a liquid storage tank, wherein the liquid storage device is detachably connected with the reagent box, the liquid storage tank is internally provided with the liquid storage tank and is used for containing auxiliary reagents, a first sealing piece is arranged at the bottom of the liquid storage tank, and a sealing cover or a second sealing piece is detachably connected to the top of the liquid storage tank. According to the utility model, the detachable liquid storage device is added on the kit, so that the sampler can be directly introduced into the kit to finish sample loading after dilution is finished in the liquid storage device, and the effort and time consumed by a user for aligning the sampling window are reduced.

Description

Liquid reservoir, combined sample detection structure and sampling detection device

Technical Field

The utility model relates to the field of test analysis, in particular to a liquid reservoir, a combined sample detection structure and a sampling detection device.

Background

Immunochromatography is a technique for achieving the purpose of detection by an antigen-antibody binding reaction occurring in the chromatographic process. Because of the advantages of simple and quick operation, no need of training for operators, no need of simple instruments, and the like, the technology has been widely applied to various fields such as food detection, drug detection, environmental monitoring, clinical diagnosis, and the like. Immunochromatography is generally used for detecting liquid to be detected by a liquid detection device, and has many applications in the life or medical industry, such as quantitative detection of target analytes by blood, urine or other biological samples.

In the existing detection process, a swab is generally used for collecting a substance to be detected, then the end of the swab is soaked in a diluted solution for dilution, and finally the diluted solution is dripped into a liquid detection device to complete subsequent detection work.

However, the above-described process requires the addition of a step of diluting the sample before the official test, and the preparation of a dilution vessel for dilution of the sample, thereby adding the devices and test steps required for the test of the sample. After the dilution is completed, the user needs to drop the mixed liquid into the sampling window of the sample detection device, and the mixed liquid is easy to drop out of the sampling window by a little carelessness, so that the user is also required to align the mixed liquid during loading. It can be seen that errors are unavoidable when performing large-scale sample testing, and that testing man-hours are also expended.

Disclosure of Invention

The utility model aims to at least solve one of the technical problems in the prior art, and provides a liquid reservoir, a combined sample detection structure and a sampling detection device, which can pre-dilute a sample and assist a user to drop a mixed liquid containing the sample to the detection device so as to finish loading.

According to an embodiment of the first aspect of the present utility model, there is provided a liquid reservoir having a liquid reservoir and a first seal disposed inside the liquid reservoir, the first seal being disposed at a bottom of the liquid reservoir; the top of the liquid storage device is detachably connected with a sealing cover, and the sealing cover can seal the top of the liquid storage device; or, the interior of the liquid storage device is also provided with a second sealing piece, and the second sealing piece can seal the top of the liquid storage cabin.

Further, the reservoir extends downward with a mating member, and an accommodating space is formed between the mating member and the bottom surface of the reservoir to accommodate the kit.

Further, the liquid reservoir extends downwards to be provided with a clamping piece, and the clamping piece is used for clamping the kit.

According to an embodiment of the first aspect of the present utility model, further, side baffles extend downwards from two sides of the liquid reservoir respectively, the edges of the two side baffles are respectively provided with a clamping piece, the clamping piece extends towards the middle of the liquid reservoir, and a sliding space is formed between the side baffles, the clamping piece and the bottom surface of the liquid reservoir.

According to an embodiment of the first aspect of the utility model, the reservoir is further provided with a guiding tube, which is connected to the top of the tank, the guiding tube being used for guiding the sampler into.

According to a second aspect of the present utility model, there is provided a combined sample detection structure, including a kit and the above-mentioned reservoir, the reservoir being detachably connected to the kit;

the inside of the kit is provided with a cavity capable of accommodating detection test paper, the top of the kit is provided with a sampling window, and the detection test paper is arranged below the sampling window;

the liquid storage cabin is positioned right above the sampling window so as to ensure the smoothness of the subsequent loading operation.

At least a part of the sample pad of the test paper is arranged right below the sampling window so as to be convenient for receiving samples dripped at the sampling window.

According to a second aspect of the present utility model, the reservoir further comprises a mating member extending downward, wherein a receiving space is defined between the mating member and a bottom surface of the reservoir, and the kit is fully or partially received in the receiving space. Still further, the mating relationship of the mating member and the cartridge is similar to the mating relationship of the drawer and the drawer slot.

Or, the liquid reservoir extends downwards to form a clamping piece, and the clamping piece is clamped and assembled with the kit.

Or, the two sides of the liquid storage device are respectively provided with side baffles in a downward extending mode, the edges of the two side baffles are respectively provided with a clamping piece, the clamping pieces extend towards the middle of the liquid storage device, and a sliding space is formed among the side baffles, the clamping pieces and the bottom surface of the liquid storage device; the liquid reservoir is in sliding connection with the kit, and the kit can slide in the sliding space.

According to a second aspect of the embodiment of the utility model, further, the end of the reservoir is provided with a limit stop which extends downwards and can abut against the end of the cartridge, thereby limiting the relative position of the reservoir and the cartridge.

According to an embodiment of the second aspect of the present utility model, further, the aperture of the sampling window is gradually narrowed from top to bottom.

According to an embodiment of the second aspect of the present utility model, further, the sampling window is covered with a screen, and a plurality of grids are provided on the screen.

According to an embodiment of the second aspect of the utility model, further, the kit comprises an upper housing and a lower housing; the sampling window is arranged on the upper shell; the upper shell is provided with an observation window for observing part or all of the detection test paper, and the upper shell and the lower shell are mutually spliced and enclosed to form a cavity.

According to a third aspect of the present utility model there is provided a sampling test device comprising a combined sample test structure as described above and a sampler which is able to extend into the top of the reservoir and which is able to break the first seal to place the reservoir in communication with the sampling window.

The beneficial effects of the embodiment of the utility model at least comprise: according to the utility model, the detachable liquid storage device is added on the kit, and the sampler can be directly poked into the kit after the dilution is completed in the liquid storage device so as to complete the sample loading, so that the effort and time consumed by a user for aligning the sampling window are reduced.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present utility model, the drawings that are required to be used in the description of the embodiments will be briefly described below. It is evident that the drawings described are only some embodiments of the utility model, but not all embodiments, and that other designs and drawings can be obtained from these drawings by a person skilled in the art without inventive effort.

FIG. 1 is a three-dimensional view of a combined sample test structure according to a second aspect of the present utility model;

FIG. 2 is an exploded view of a combined sample testing structure according to a second aspect of the present utility model;

FIG. 3 is a cross-sectional view of a combined sample test structure according to a second aspect of the utility model;

fig. 4 is a three-dimensional view of a reservoir 300 according to an embodiment of the first aspect of the present utility model.

Reference numerals: 100-kit, 110-cavity, 120-sampling window, 130-upper shell, 131-observation window, 132-anti-slip convex point, 140-lower shell, 200-test paper, 300-reservoir, 310-liquid storage tank, 320-first sealing element, 330-side baffle, 340-clamping element, 350-limit baffle, 360-guiding tube and 400-accommodation space.

Detailed Description

Reference will now be made in detail to the present embodiments of the present utility model, examples of which are illustrated in the accompanying drawings, wherein the accompanying drawings are used to supplement the description of the written description so that one can intuitively and intuitively understand each technical feature and overall technical scheme of the present utility model, but not to limit the scope of the present utility model.

In the description of the present utility model, it should be understood that references to orientation descriptions such as upper, lower, front, rear, left, right, etc. are based on the orientation or positional relationship shown in the drawings, are merely for convenience of description of the present utility model and to simplify the description, and do not indicate or imply that the apparatus or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present utility model.

In the description of the present utility model, a number means one or more, a number means two or more, and greater than, less than, exceeding, etc. are understood to not include the present number, and above, below, within, etc. are understood to include the present number. The description of the first and second is for the purpose of distinguishing between technical features only and should not be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.

In the description of the present utility model, unless explicitly defined otherwise, terms such as arrangement, installation, connection, etc. should be construed broadly and the specific meaning of the terms in the present utility model can be reasonably determined by a person skilled in the art in combination with the specific contents of the technical scheme.

In the conventional sample detection device, the sample is generally detected, and the viscous sample or the powdery sample is difficult to directly inject into the sample detection device and finish loading due to poor fluidity. Therefore, the user needs to dilute the sample with the diluting solution in advance, and the sample can be injected into the sample detection device for detection after the sample is pretreated. However, the method clearly requires that the user prepares devices such as a dilution container, a rubber head dropper for transferring the mixed solution, a pipette and the like in advance, and has higher requirements on the preparation of materials for detection work; in addition, after dilution, the user is required to transfer the mixed solution and drop the mixed solution onto the sample detection device to finish loading, and in the process, the user is required to align the pipetting device with a sampling window on the sample detection device, and the mixed solution is easy to drop outside the sampling window by a little careless, so that pipetting failure is caused. Particularly in the large-batch detection work, the conventional detection process consumes more materials and man-hours, so that a sample detection device capable of simplifying the detection process is highly demanded.

In this regard, embodiments of the first aspect of the present utility model provide a reservoir 300 for diluting a sample; the second aspect of the present utility model provides a combined sample detection structure in which the kit 100 is detachably connected to the reservoir 300 for performing a detection operation on a sample. After the sample is sampled using the sampler, the sampler carrying the sample may be inserted into the reservoir 300 and dilution of the sample performed therein. After the dilution is completed, the sampler is further poked in, so that the first sealing element 320 in the liquid reservoir 300 can be damaged, and the mixed liquid with the sample flows into the kit 100 from the notch of the first sealing element 320 for sample detection. Thus, the reservoir 300 not only completes the dilution of the sample, but also limits the poking position of the sampler, thereby assisting the user in accurately extending the sampler into the sampling window 120 in the kit 100 for loading. The combined sample detection structure can simplify the sample detection flow and improve the detection efficiency.

The first seal 320 may be any of a sealing membrane, a sealing rubber stopper, a sealing silicone stopper, and similar closure items.

Referring to fig. 1, a combined sample test structure according to an embodiment of the second aspect of the present utility model includes a kit 100, a test strip 200, and a reservoir 300 according to an embodiment of the first aspect of the present utility model. The kit 100 is a main structure of the combined sample detection structure, referring to fig. 2, a cavity 110 capable of accommodating a detection test paper 200 is arranged in the kit, a sampling window 120 is formed in the top of the kit 100, and the detection test paper 200 is arranged below the sampling window 120, so that a sample can enter from the sampling window 120 and be loaded on the detection test paper 200.

In some embodiments, the kit 100 is a unitary structure to protect the test strip 200 positioned therein. In this embodiment, the kit 100 includes an upper housing 130 and a lower housing 140, the upper housing 130 is provided with an observation window 131 for partially or completely observing the test paper 200, and after the test paper 200 is loaded, a user can observe the detection result on the test paper 200 through the observation window 131 by eyes or a detection device. The upper case 130 and the lower case 140 are spliced with each other and enclose a cavity 110, and the upper case 130 and the lower case 140 may be fixed to each other by a socket structure, a snap structure, or a welding manner.

The reservoir 300 is detachably connected with the kit 100, so that it can be separately placed during transportation or storage, and more fully utilizes the storage space; and when in use, the two can be connected with each other to jointly complete the detection work. Referring to fig. 3, a liquid storage tank 310 is provided inside the liquid reservoir 300, and the liquid storage tank 310 is located above the sampling window 120 after the liquid reservoir 300 and the kit 100 are mounted in place. The tank 310 is open at the top and bottom and is provided with a first seal 320 at the bottom, and the tank 310 contains an auxiliary reagent. In the present utility model, the auxiliary reagent means a reagent for facilitating sample loading, such as a diluent.

In some embodiments, when dilution is desired, the user is required to inject an auxiliary reagent into the reservoir 310 before dilution of the sample can be performed. In this embodiment, however, the auxiliary agent is pre-stored in the reservoir 310, and in order to prevent the auxiliary agent from flowing out of the reservoir 310 during transportation or storage, a sealing structure is installed at the top of the reservoir 310 to seal the reservoir 310. For the sealing mechanism, a cover is used in some embodiments, which is detachably connected to the top of the liquid storage compartment 310, specifically by a threaded connection, a snap connection or an interference fit connection, and the cover can be removed therefrom when opening is required. In other embodiments, the reservoir 300 is provided with a second seal disposed on top of the reservoir 310, sealing the reservoir 310 when not in use, and a user holding the sampler to break the second seal to access the reservoir 310 for dilution when sample dilution is desired.

For the connection of the reservoir 300 to the kit 100, in some embodiments, the two are connected and limited to each other by means of a snap or latch. In this embodiment, the reservoir 300 is slidably connected to the kit 100, and the reservoir 300 can be slid in from one end of the kit 100. Specifically, referring to fig. 4, the side baffles 330 extend downward from both sides of the reservoir 300, and the edges of both side baffles 330 are provided with the clamping members 340, and the clamping members 340 extend toward the middle of the reservoir 300, so that an accommodating space 400 is formed between the side baffles 330, the clamping members 340 and the bottom surface of the reservoir 300. The two clamping pieces 340 may have a gap therebetween, or may extend to the point where they meet to form an integral structure. All schemes that can accommodate the kit 100 in whole or in part and ensure the cooperation of the kit 100 and the reservoir 300 are within the scope of the present utility model. For example, the kit 100 may be coupled to the reservoir 300 by fastening, engaging, sliding, or the like.

Further, the end of the liquid reservoir 300 is provided with a limit baffle 350, and the limit baffle 350 extends downward and can be abutted against the end of the reagent kit 100, so that when the limit baffle 350 abuts against the end of the reagent kit 100, the liquid reservoir 300 and the reagent kit 100 can be limited from further sliding, and the relative position of the liquid reservoir 300 and the reagent kit 100 is limited, so that the liquid reservoir 310 is just above the sampling window 120. Specifically, a gap may be left between the limit stop 350 and the bottom clamping member 340, and the limit stop 350 may also extend to the clamping member 340 to form an integral box-like structure, similar to the matching relationship between the drawer and the drawer slot.

Further, a guide tube 360 is provided at the top of the reservoir 300, which is connected to the top of the reservoir 310, for guiding the sampler into and inserting into the reservoir 310.

Further, the aperture of the sampling window 120 is gradually narrowed from top to bottom, so that for the mixed liquid dropped on the edge of the sampling window 120, it can flow into the test paper 200 along the inclined surface of the edge of the sampling window 120.

Further, the sampling window 120 is further covered with a screen, and a plurality of grids are provided on the screen, through which the mixed solution can flow. The arrangement of the screen is used for reducing the impact force when the mixed liquid falls, so that the sample is prevented from splashing due to overlarge impact force, and the waste of the sample is prevented.

Further, the surface of the upper housing 130 is provided with anti-slip bumps 132 to facilitate the grip of the user and increase the relative friction with the user's fingers.

An embodiment of the third aspect of the present utility model relates to a sampling detection apparatus. The sampling detection device not only comprises the combined sample detection structure in any embodiment, but also comprises a sampler. The sampler is used to collect a sample, and may employ a swab, a cotton swab, sampling cotton, or other device capable of collecting a sample. The sampler can extend into the top of the reservoir 310 to add the sample to the auxiliary reagent of the reservoir 310 for dilution. After the dilution is completed, the sampler continues to extend into, and the first sealing element 320 positioned at the bottom of the liquid storage tank 310 is poked, so that the mixed liquid with the sample flows into the sampling window 120 from the notch of the first sealing element 320 and contacts with the detection test paper to finish the loading.

Next, the method for using the sampling detection device is described:

s100, acquiring a sample by using a sampler;

s200, taking out the kit 100 and the liquid reservoir 300, and mounting the liquid reservoir 300 on the kit 100;

s300, inserting a sampler with a sample attached to the sampler into the liquid storage tank 300, so that the sample in the sampler is soaked in the auxiliary reagent in the liquid storage tank 310;

s400, standing, and waiting for the sample and the auxiliary reagent to be fully mixed to form a mixed solution;

s500, holding the sampler to continuously apply pressure, and poking the first sealing element 320 by the sampler so that the mixed liquid flows out of the notch at the first sealing element 320 and flows into the cavity 110 of the kit 100 through the sampling window 120 to be fully contacted with the detection test paper 200;

s600, sample loading is performed on the test paper 200;

s700, observing and recording a detection result on the detection test paper 200 through naked eyes or corresponding equipment to finish sample detection;

s800, the sampler is extracted, the liquid reservoir 300 is separated from the kit 100, and the sample detection is finished.

While the preferred embodiments of the present utility model have been illustrated and described, the present utility model is not limited to the embodiments, and various equivalent modifications and substitutions can be made by those skilled in the art without departing from the spirit of the present utility model, and these equivalent modifications and substitutions are intended to be included in the scope of the present utility model as defined in the appended claims.

Claims (10)

1. A reservoir (300), characterized by: the inside of the device is provided with a liquid storage tank (310) and a first sealing piece (320), wherein the first sealing piece (320) is arranged at the bottom of the liquid storage tank (310); a sealing cover is detachably connected to the top of the liquid storage device (300), and the sealing cover can seal the top of the liquid storage device (300); alternatively, a second seal is also provided inside the reservoir (300), which second seal is capable of sealing the top of the reservoir (310).

2. A reservoir according to claim 1, wherein: the liquid storage device (300) is further provided with a guide pipe (360), the guide pipe (360) is connected with the top of the liquid storage cabin (310), and the guide pipe (360) is used for guiding the sampler to enter.

3. Combined sample detection structure, its characterized in that: comprising a kit (100) and a reservoir (300) according to claim 1 or 2, said reservoir (300) being detachably connected to said kit (100);

the kit (100) is provided with a sampling window (120), and the liquid storage cabin (310) is positioned right above the sampling window (120).

4. A combined sample detection structure according to claim 3, wherein: the liquid reservoir is downwards extended with a matching piece, an accommodating space (400) is formed between the matching piece and the bottom surface of the liquid reservoir (300), and the kit (100) is wholly or partially accommodated in the accommodating space (400); or, the liquid reservoir extends downwards to form a clamping piece, and the clamping piece is assembled with the kit (100) in a clamping way.

5. A combined sample detection structure according to claim 3, wherein: the end of the liquid reservoir (300) is provided with a limit baffle (350), and the limit baffle (350) extends downwards and can be abutted with the end of the reagent box (100), so that the relative position of the liquid reservoir (300) and the reagent box (100) is limited.

6. A combined sample detection structure according to claim 3, wherein: the caliber of the sampling window (120) gradually narrows from top to bottom.

7. A combined sample detection structure according to claim 3, wherein: the sampling window (120) is covered with a screen, and a plurality of grids are arranged on the screen.

8. A combined sample detection structure according to claim 3, wherein: the inside of kit (100) is equipped with test paper (200) and can hold cavity (110) of test paper (200), at least a portion of the sample pad of test paper (200) is located the below of sampling window (120).

9. The combined sample detection structure according to claim 8, wherein: the kit (100) comprises an upper shell (130) and a lower shell (140), and the sampling window (120) is arranged on the upper shell (130); the upper shell (130) is further provided with an observation window (131) for observing the detection test paper (200), and the upper shell (130) and the lower shell (140) are mutually spliced and enclosed to form the cavity (110).

10. Sampling test device, characterized in that it comprises a combined sample test structure according to any one of claims 3 to 9 and a sampler which is able to protrude from the top of the reservoir (310) and to break the first seal (320) in order to put the reservoir (310) in communication with the sampling window (120).