CN219922755U

CN219922755U - Cell culture auxiliary device

Info

Publication number: CN219922755U
Application number: CN202320574851.1U
Authority: CN
Inventors: 杨永利; 张森; 李丹
Original assignee: Shaanxi Zhongyan Institute Of Regenerative Medicine Co ltd; Chengdu Anyu Regenerative Medicine Technology Co ltd
Current assignee: Shaanxi Zhongyan Institute Of Regenerative Medicine Co ltd; Chengdu Anyu Regenerative Medicine Technology Co ltd
Priority date: 2023-03-22
Filing date: 2023-03-22
Publication date: 2023-10-31
Anticipated expiration: 2033-03-22

Abstract

The utility model discloses a cell culture auxiliary device, which belongs to the technical field of cell culture and comprises a culture chamber, a sealing door plate, mounting grooves, a storage rack and a sliding rail, wherein the sealing door plate is hinged in front of the culture chamber, the mounting grooves are fixedly arranged on two sides of the inner wall of the culture chamber, the storage rack is arranged between the inner part of the culture chamber and the mounting grooves, the sliding rail is fixedly arranged on the upper side and the lower side of the culture chamber, the sliding rail is arranged in an opposite arc shape, and a shaking mechanism which is convenient for shaking cultured cells in a test tube is arranged on the outer side of the storage rack. According to the utility model, a worker opens the servo motor to drive the eccentric wheel to rotate at medium speed, so that the eccentric wheel continuously pushes the fixed plate to drive the storage rack to continuously shake left and right through the telescopic rods at the two sides and the outer springs, a plurality of cells to be cultured in the test tubes are driven to shake uniformly and disperse, and the efficiency of shaking the cells to be cultured in the test tubes simultaneously is higher while the worker does not need to shake the cells to be cultured in the test tubes manually.

Description

Cell culture auxiliary device

Technical Field

The utility model belongs to the technical field of cell culture, and particularly relates to a cell culture auxiliary device.

Background

Cell culture is a method of simulating the living environment of cells to allow the cells to live and grow in the simulated environment, and thus a cell culture auxiliary device is required because a large number of cells are obtained.

According to the search, the application number is CN202221848315.8, and the shaking type cell culture device is provided with a structure for driving a culture container to swing left and right in a swinging manner, so that culture fluid in the culture container is swung in the swinging manner, and meanwhile, the culture container is driven to synchronously rotate through a rotating structure, so that the purpose of swinging can be achieved, and the bottom of the culture container is not piled up through simultaneous working of the swinging structure and the rotating structure, the cell culture time is shortened, and the culture efficiency is improved; the disadvantages are as follows:

when the staff uses this kind of shake type cell culture device, hold the cell of culture in vitro and shake even processing, promote the structure through the actuating lever constantly flexible and drive and shake the culture vessel and shake about reciprocating, make the inside culture solution of culture vessel shake even processing, and when the structure of swaing drives the culture vessel and shake of great radian, the inside cell solution of culture vessel also can be because of inertia, and be difficult to produce certain mobility for shake even effect to the inside cell solution of culture vessel relatively poor.

Disclosure of Invention

The utility model aims at: in order to solve the problem that the shaking effect of the shaking type cell culture device on a cell solution is poor, the cell culture auxiliary device is provided.

The technical scheme adopted by the utility model is as follows: cell culture auxiliary device, including cultivateing room, sealed door plant, mounting groove, supporter and slide rail, cultivate the place ahead articulated sealed door plant that is provided with of room, cultivate room inner wall both sides fixed mounting and have the mounting groove, cultivate and be provided with the supporter between the room inside being close to the mounting groove, cultivate room upper and lower both sides fixed mounting and have the slide rail, and the slide rail is relative arc shape setting, the supporter outside is provided with the even mechanism of shaking that conveniently cultivates the cell in the test tube, the slide rail outside is provided with the even homothermal removal constant temperature mechanism of messenger's cultivate room inside temperature.

The shaking mechanism comprises a limiting groove A, a limiting frame, a limiting cover plate, a storage groove A, a storage groove B, a telescopic rod, a first sliding frame, a limiting groove B, a fixing plate, a servo motor and an eccentric wheel, wherein the limiting cover plate is connected to the upper portion of the sliding frame through bolts, the storage groove A is embedded below the limiting cover plate, the storage groove A is provided with a plurality of limiting frames and is arranged at equal intervals in parallel, the storage groove B is provided with a plurality of limiting frames close to the lower portion of the storage groove A and is arranged at equal intervals in parallel, the telescopic rods are fixedly arranged on two sides of the sliding frame, springs are arranged on the outer sides of the telescopic rod in a matched mode, the first sliding frame is fixedly arranged on the end portion of the telescopic rod, the first sliding frame is arranged on the inner side of the mounting groove in a matched mode, the lower portion of the sliding frame is embedded below the mounting groove, the limiting groove B is arranged on the lower portion of the limiting groove in a matched mode, the limiting frame is arranged between the limiting groove B and the inner side of the limiting groove A in a sliding mode, the limiting frame and the lower portion of the sliding frame are connected to the servo motor in a matched mode, and the first sliding frame is arranged on the upper portion of the sliding frame is close to the side of the servo motor in a matched mode, and the first sliding frame is fixedly arranged on the upper portion of the sliding frame through the fixing frame.

The movable constant temperature mechanism is composed of a second sliding frame, heat preservation lamps and electric rollers, the second sliding frame is oppositely arranged above the sliding rail, the heat preservation lamps are fixedly installed on two sides of the second sliding frame relatively, the electric rollers are installed under the second sliding frame Fang Sijiao, and the electric rollers are arranged inside the opposite sliding rail in a fit sliding mode.

In summary, due to the adoption of the technical scheme, the beneficial effects of the utility model are as follows:

1. this kind of cell culture auxiliary device is through being provided with telescopic link and eccentric wheel, can make the staff open servo motor and drive the medium-speed rotation of eccentric wheel, make the eccentric wheel constantly promote the fixed plate and drive the supporter and pass through both sides telescopic link and outside spring and constantly stretch out and draw back, make the supporter control constantly rock, drive the cell that needs to cultivate in a plurality of test tubes and shake even dispersion treatment, when will not need the staff to shake even to the cell that needs to cultivate in the test tube manually anymore, improve the effect that shakes even efficiency higher to the cell that needs to cultivate in a plurality of test tubes simultaneously.

2. This kind of cell culture auxiliary device is through being provided with heat preservation lamp and electronic gyro wheel, when can making the staff close sealed door plant and open two pairs of heat preservation lamps and carry out constant temperature heating treatment to cultivateing room inside temperature, the staff opens the servo motor that electronic gyro wheel was supporting again and drives electronic gyro wheel and constantly slide in slide rail inside, when driving second continuous side-to-side of carriage, will make the change that two pairs of heat preservation lamps constantly carry out the position, it heats constant temperature to cultivate room inside temperature to improve two pairs of heat preservation lamps, make temperature distribution even around a plurality of test tubes, carry out even constant temperature cultivation treatment's effect.

Drawings

FIG. 1 is a schematic diagram showing a schematic perspective view of a cell culture assisting apparatus according to the present utility model;

FIG. 2 is a schematic diagram showing a schematic cross-sectional structure of a cell culture auxiliary device according to the present utility model;

FIG. 3 is a schematic diagram of the enlarged construction of FIG. 2 at A in accordance with the present utility model;

FIG. 4 is a schematic diagram of a side view three-dimensional structure of the heat preservation lamp in the utility model;

fig. 5 is a schematic diagram showing the second enlarged structure of the embodiment a in fig. 2 according to the present utility model.

The marks in the figure: 1. a culture chamber; 101. sealing the door plate; 102. a mounting groove; 103. a limit groove A; 104. a limiting frame; 2. a commodity shelf; 201. a limit cover plate; 202. a storage groove A; 203. a storage groove B; 204. a telescopic rod; 205. a first sliding frame; 206. a limit groove B; 207. a fixing plate; 3. a servo motor; 301. an eccentric wheel; 4. a slide rail; 401. a second sliding frame; 402. a heat preservation lamp; 403. an electric roller; 5. damping telescopic rod; 501. and a limiting block.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

In the utility model, the following components are added:

embodiment one: referring to fig. 1-5, a cell culture auxiliary device, including cultivateing room 1, sealed door plant 101, mounting groove 102, supporter 2 and slide rail 4, cultivate room 1 the place ahead and articulate and be provided with sealed door plant 101, cultivate room 1 inner wall both sides fixed mounting has mounting groove 102, cultivate room 1 inside and be provided with supporter 2 between being close to mounting groove 102, cultivate room 1 upper and lower both sides fixed mounting has slide rail 4, and slide rail 4 is relative arc form setting, the supporter 2 outside is provided with the mechanism of shaking evenly that conveniently cultivates the cell in the test tube, the slide rail 4 outside is provided with the removal constant temperature mechanism that makes cultivate the inside temperature of room even constant temperature.

Referring to fig. 2 and 3, the shaking mechanism further comprises a limit groove a103, a limit frame 104, a limit cover plate 201, a storage groove a202, a storage groove B203, a telescopic rod 204, a first slide frame 205, a limit groove B206, a fixing plate 207, a servo motor 3 and an eccentric wheel 301;

the upper part of the storage rack 2 is connected with a limiting cover plate 201 through bolts, a plurality of storage grooves A202 are embedded and arranged below the limiting cover plate 201, the storage grooves A202 are arranged in parallel at equal intervals, a plurality of storage grooves B203 are embedded and arranged above the storage rack 2 near the lower part of the storage groove A202, the storage grooves B203 are arranged in parallel at equal intervals, telescopic rods 204 are fixedly arranged at two sides of the storage rack 2, springs are arranged outside the telescopic rods 204 in a matched mode, a first sliding frame 205 is fixedly arranged at the side of the end part of the telescopic rods 204, the first sliding frame 205 is arranged inside the mounting groove 102 in a matched sliding mode, a limiting groove B206 is embedded and arranged below the first sliding frame 205, a limiting groove A103 is embedded and arranged below the mounting groove 102 near the lower part of the limiting groove B206, a limiting frame 104 is arranged between the limiting groove B206 and the inner side of the limiting groove A103 in a sliding mode, the limiting frame 104 and the lower part of the first sliding frame 205 are connected through bolts, a fixing plate 207 is fixedly arranged on the side of the shelf 2 close to the upper part of the first slide frame 205, a servo motor 3 is fixedly arranged on the side of the culture room 1, an eccentric wheel 301 is connected with the servo motor 3 through an output shaft, when a worker needs to culture cells placed in a plurality of test tubes at constant temperature, a sealing door plate 101 is opened, bolts below the limiting frame 104 are screwed out, the limiting frame 104 is pulled to slide out of the inner sides of the limiting groove B206 and the limiting groove A103, the shelf 2 is pulled to drive the first slide frame 205 to slide out of the mounting groove 102, the shelf 2 is taken out of the culture room 1, bolts on two sides of the limiting cover plate 201 are screwed out, the limiting cover plate 201 is taken down from the upper part of the shelf 2, a plurality of test tubes with cells are placed in the storage groove B203, the limiting cover plate 201 is placed above the shelf 2, the storage grooves A202 slide to the tops of the test tubes, the worker fixes the limiting test tubes by screwing bolts between the limiting cover plate 201 and the shelf 2, and place supporter 2 in cultivate room 1, drive both sides carriage one 205 slide into inside relative mounting groove 102, and slide limit frame 104 between limit groove B206 and the limit groove A103 inboard, and screw in the bolt fastening back, the servo motor 3 is opened to the staff and drive eccentric wheel 301 medium-speed rotation, make eccentric wheel 301 constantly promote fixed plate 207 and drive supporter 2 and constantly stretch out and draw back through both sides telescopic link 204 and outside spring, make supporter 2 constantly rock about, drive a plurality of test tubes in need cultivate the cell and shake even dispersion treatment, when no longer need the staff to shake evenly to the cell that needs cultivate in the test tube manually, shake even efficiency higher to the cell that needs cultivate in a plurality of test tubes simultaneously.

Referring to fig. 2 and 4, the movable constant temperature mechanism is further composed of a second sliding frame 401, a heat preservation lamp 402 and an electric roller 403;

the slide rail 4 top is provided with slide frame two 401 relatively, slide frame two 401 both sides relative fixed mounting has heat preservation lamp 402, fang Sijiao installs electronic gyro wheel 403 under the slide frame two 401, and electronic gyro wheel 403 agrees with the slip setting inside relative slide rail 4, after a plurality of test tubes in need cultivate the cell and shake even processing simultaneously, the staff closes sealed door plant 101 and opens two pairs of heat preservation lamps 402 and carry out constant temperature heating treatment to cultivate room 1 inside temperature, the staff opens the servo motor that the electronic gyro wheel 403 is supporting again and drives electronic gyro wheel 403 and constantly slides about in slide rail 4 inside, when driving slide frame two 401 constantly slides about, will make two pairs of heat preservation lamps 402 constantly carry out the change of position, make two pairs of heat preservation lamps 402 evenly heat constant temperature to cultivate room 1 inside temperature, make temperature distribution even around a plurality of test tubes, carry out even constant temperature cultivation treatment.

Referring to fig. 2-4, further, the electric roller 403 is electrically connected with the storage battery through a matched servo motor and control panel, and the servo motor 3 and the heat preservation lamp 402 are electrically connected with the storage battery through the control panel.

Example two

Referring to fig. 5, in the above technical scheme, except that the limit groove B206 is embedded below the first slide frame 205, the limit groove a103 is embedded below the mounting groove 102 near the limit groove B206, the limit groove B206 and the inside of the limit groove a103 are slidably provided with the limit frame 104, and the limit frame 104 and the first slide frame 205 are connected by bolts, another embodiment is provided except that the technical scheme is adopted, the damping telescopic rod 5 is fixedly mounted above the inner wall of the limit groove B206, a spring is arranged outside the damping telescopic rod 5, the limit block 501 is fixedly mounted below the end of the damping telescopic rod 5, the limit block 501 is matched with the inside of the limit groove a103, when a worker needs to detach the shelf 2, the limit block 501 is pushed to slide out of the limit groove a103, and after the limit block 5 and the outside spring are driven to shrink, the shelf 2 is pulled to drive the first slide frame 205 to slide out of the mounting groove 102, and when the shelf 2 needs to be mounted, the limit block 501 is driven to shrink by the outside spring, and the limit block 501 is pushed to slide into the mounting groove a position 2, compared with the first embodiment, the first embodiment is more convenient to detach the limit block 501 from the inside the limit groove a.

Working principle: firstly, when a worker needs to cultivate cells in a plurality of test tubes at constant temperature, the sealing door plate 101 is opened, bolts below the limiting frame 104 are screwed out, after the limiting frame 104 is pulled to slide out of the inner sides of the limiting groove B206 and the limiting groove A103, the limiting frame 2 is pulled to drive the sliding frame I205 to slide out of the mounting groove 102, after the storage frame 2 is taken out of the cultivating chamber 1, bolts at two sides of the limiting cover plate 201 are screwed out, after the limiting cover plate 201 is taken down from above the storage frame 2, the worker places a plurality of test tubes with the cells in the storage groove B203, then places the limiting cover plate 201 above the storage frame 2, so that a plurality of storage grooves A202 slide to the top of the test tubes to limit and fix the test tubes, then, the worker screws in the bolts between the limiting cover plate 201 and the storage frame 2, places the storage frame 2 in the cultivating chamber 1, drives the sliding frames I205 at two sides to slide into the opposite mounting grooves 102, and the limiting frame 104 slides into the space between the inner sides of the limiting groove B206 and the limiting groove A103, after the limiting frame is screwed into the limiting groove A103 and is fixed by a bolt, a worker opens the servo motor 3 to drive the eccentric wheel 301 to rotate at medium speed, so that the eccentric wheel 301 continuously pushes the fixing plate 207 to drive the storage frame 2 to continuously stretch and retract through the telescopic rods 204 on the two sides and the outer springs, the storage frame 2 continuously shakes left and right to drive a plurality of cells to be cultured in the test tube to uniformly shake and disperse the cells to be cultured in the test tube, the worker is not required to manually shake the cells to be cultured in the test tube, finally, the worker closes the sealing door plate 101 and opens two pairs of heat preservation lamps 402 to perform constant temperature heating treatment on the inner temperature of the culture chamber 1, and simultaneously, the worker opens the servo motor matched with the electric roller 403 to drive the electric roller 403 to continuously slide left and right in the slide rail 4 to drive the slide frame two pairs of heat preservation lamps 402 to continuously perform position change, the two pairs of heat preservation lamps 402 are used for uniformly heating and keeping the temperature in the culture chamber 1, so that the temperature distribution around a plurality of test tubes is uniform, and uniform constant temperature culture treatment is performed.

The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the utility model.

Claims

1. Cell culture auxiliary device, including cultivateing room (1), sealed door plant (101), mounting groove (102), supporter (2) and slide rail (4), cultivate room (1) the place ahead and articulate and be provided with sealed door plant (101), cultivate room (1) inner wall both sides fixed mounting has mounting groove (102), cultivate room (1) inside and be provided with supporter (2) between being close to mounting groove (102), cultivate room (1) upper and lower both sides fixed mounting has slide rail (4), and slide rail (4) are relative arc form setting, its characterized in that: the rack (2) outside is provided with the even mechanism of shaking that conveniently shakes the cell of cultivating in the test tube, slide rail (4) outside is provided with the removal constant temperature mechanism that makes the inside temperature of cultivateing the room even constant temperature.

2. A cell culture assistance device according to claim 1 wherein: the shaking mechanism consists of a limiting groove A (103), a limiting frame (104), a limiting cover plate (201), a storage groove A (202), a storage groove B (203), a telescopic rod (204), a first sliding frame (205), a limiting groove B (206), a fixed plate (207), a servo motor (3) and an eccentric wheel (301);

the utility model discloses a servo motor, including supporter (2), limiting cover board (201), supporter (2), limiting cover board (201) top is provided with puts thing groove A (202) through bolted connection, supporter (2) top is close to and puts thing groove A (202) below embedding and be provided with put thing groove B (203), supporter (2) both sides fixed mounting has telescopic link (204), telescopic link (204) tip side fixed mounting has first (205) of carriage, first (205) below embedding of carriage is provided with spacing groove B (206), the mounting groove (102) below is close to spacing groove B (206) below embedding and is provided with spacing groove A (103), slide between spacing groove B (206) and the spacing groove A (103) inboard is provided with spacing frame (104), and spacing frame (104) and first (205) below are through bolted connection, supporter (2) side is close to first (205) top fixed mounting has fixed plate (207), cultivate room (1) side fixed mounting has servo motor (3), servo motor (3) are through eccentric connection (301).

3. A cell culture assistance device according to claim 1 wherein: the movable constant temperature mechanism consists of a second sliding frame (401), a heat preservation lamp (402) and an electric roller (403);

the utility model discloses a sliding rail, including slide rail (4), slide frame two (401) are provided with relatively above slide rail (4), slide frame two (401) both sides are fixed mounting relatively has heat preservation lamp (402), electronic gyro wheel (403) are installed to Fang Sijiao under slide frame two (401), and electronic gyro wheel (403) fit sliding setting is inside slide rail (4) relatively.

4. A cell culture assistance device according to claim 2 wherein: the storage grooves A (202) are arranged in parallel at equal intervals, and the storage grooves B (203) are arranged in parallel at equal intervals.

5. A cell culture assistance device according to claim 2 wherein: and a spring is arranged on the outer side of the telescopic rod (204) in a matched mode.

6. A cell culture assistance device according to claim 2 wherein: the first sliding frame (205) is matched with the inner side of the mounting groove (102) in a sliding manner.