CN219896005U - Experimental mouse radiotherapy fixing device that can get warm - Google Patents
Experimental mouse radiotherapy fixing device that can get warm Download PDFInfo
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- CN219896005U CN219896005U CN202222379796.9U CN202222379796U CN219896005U CN 219896005 U CN219896005 U CN 219896005U CN 202222379796 U CN202222379796 U CN 202222379796U CN 219896005 U CN219896005 U CN 219896005U
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- 238000001959 radiotherapy Methods 0.000 title claims abstract description 26
- 238000010438 heat treatment Methods 0.000 claims abstract description 34
- 230000036760 body temperature Effects 0.000 claims abstract description 11
- 239000007779 soft material Substances 0.000 claims description 4
- 239000004020 conductor Substances 0.000 claims description 3
- 238000002474 experimental method Methods 0.000 claims description 3
- 241000581650 Ivesia Species 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims 3
- 238000010792 warming Methods 0.000 claims 3
- 239000011810 insulating material Substances 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 abstract description 40
- 241000699670 Mus sp. Species 0.000 abstract description 23
- 206010002091 Anaesthesia Diseases 0.000 abstract description 5
- 230000037005 anaesthesia Effects 0.000 abstract description 5
- 238000009413 insulation Methods 0.000 abstract description 2
- 238000004321 preservation Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 239000012774 insulation material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 230000002631 hypothermal effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000000693 radiobiological effect Effects 0.000 description 1
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Abstract
本实用新型公开了一种可取暖的实验小鼠放疗固定装置,包括固定台,固定台呈长方体形,内部安装有加热片,控制器和电源,固定台上表面并列设置有数个小鼠固定槽,小鼠固定槽的顶端设置有放置小鼠头部的突出部,突出部连接有可开闭的头部固定环,小鼠固定槽的底端设置有用以夹持小鼠尾巴的尾架,小鼠固定槽的两侧设有固定小鼠四肢的固定夹,加热片设于小鼠固定槽下方,小鼠固定槽内设有温度传感器,本实用新型对实验小鼠进行放疗固定的同时实现保温、保暖,降低因小鼠放疗过程中因麻醉体温降低导致的死亡发生率。
The utility model discloses a heating and radiotherapy fixing device for experimental mice, which includes a fixing table. The fixing table is in the shape of a rectangular parallelepiped. A heating sheet, a controller and a power supply are installed inside. Several mouse fixing slots are arranged side by side on the upper surface of the fixing table. , the top of the mouse fixing groove is provided with a protruding part for placing the mouse's head, the protruding part is connected with an openable and closable head fixing ring, and the bottom end of the mouse fixing groove is provided with a tail frame for holding the mouse's tail. Fixing clips for fixing the limbs of the mouse are provided on both sides of the mouse fixing trough. The heating sheet is arranged below the mouse fixing trough. A temperature sensor is provided in the mouse fixing trough. This utility model can perform radiotherapy and fixation on experimental mice at the same time. Insulation and warmth can reduce the incidence of death caused by lowering body temperature during anesthesia in mice during radiotherapy.
Description
技术领域Technical field
本实用新型涉及动物实验设备技术领域,具体涉及一种可取暖的实验小鼠放疗固定装置。The utility model relates to the technical field of animal experimental equipment, in particular to a radiotherapy fixation device for heating experimental mice.
背景技术Background technique
开展放射生物学实验时,经常需要对大量的实验小鼠进行放射治疗(放疗)。对实验小鼠执行放疗操作之前需要先将实验小鼠进行全身短效麻醉,再将小鼠固定在台面上进行放疗。目前现有的技术是小鼠麻醉后固定在塑料板或者其他无保温、取暖效果的装置上。而麻醉后的实验小鼠因外周血管扩张,散热增加,体温会降低,此外,由于放射治疗仪器需要保持在20℃的环境温度,明显增加麻醉小鼠因体温过低而死亡的风险,因此设计一种可对实验小鼠进行放疗固定,同时实现保温、保暖效果的装置是十分有必要的。When conducting radiobiological experiments, it is often necessary to perform radiation therapy (radiotherapy) on a large number of experimental mice. Before performing radiotherapy on experimental mice, the experimental mice need to be given general short-acting anesthesia, and then the mice are fixed on the table for radiotherapy. The current existing technology is that mice are anesthetized and fixed on plastic plates or other devices without thermal insulation or heating effects. After anesthesia, the body temperature of experimental mice will decrease due to peripheral blood vessel dilation and increased heat dissipation. In addition, because the radiotherapy equipment needs to be maintained at an ambient temperature of 20°C, the risk of death of anesthetized mice due to hypothermia is significantly increased. Therefore, the design A device that can perform radiotherapy and immobilize experimental mice while achieving heat preservation and heat preservation effects is very necessary.
实用新型内容Utility model content
本实用新型的目的在于克服现有技术的缺点,提供一种可取暖的实验小鼠放疗固定装置,对实验小鼠进行放疗固定的同时实现保温、保暖,降低因小鼠放疗过程中因麻醉体温降低导致的死亡发生率。The purpose of this utility model is to overcome the shortcomings of the prior art and provide a heating and radiotherapy fixation device for experimental mice, which can achieve heat preservation and warmth while fixing experimental mice for radiotherapy, and reduce the body temperature of mice due to anesthesia during radiotherapy. Reduce the incidence of death.
为了达到上述目的,本实用新型提供一种可取暖的实验小鼠放疗固定装置,包括固定台,所述固定台呈长方体形,所述固定台为中空结构,内部安装有加热片,控制器和电源,所述固定台上表面并列设置有数个小鼠固定槽,所述小鼠固定槽的顶端设置有放置小鼠头部的突出部,突出部连接有可开闭的头部固定环,所述小鼠固定槽的底端设置有用以夹持小鼠尾巴的尾架,所述小鼠固定槽的两侧设有固定小鼠四肢的固定夹,所述加热片设于小鼠固定槽下方,所述小鼠固定槽内设有温度传感器。In order to achieve the above purpose, the present utility model provides a heating fixed device for radiotherapy of experimental mice, which includes a fixed table. The fixed table is in the shape of a rectangular parallelepiped. The fixed table is a hollow structure with a heating plate, a controller and a controller installed inside. power supply, several mouse fixing slots are arranged side by side on the upper surface of the fixing table, and the top of the mouse fixing slot is provided with a protruding part for placing the mouse head, and the protruding part is connected with an openable and closable head fixing ring, so The bottom end of the mouse fixing trough is provided with a tail frame for holding the tail of the mouse. Both sides of the mouse fixing trough are provided with fixing clips for fixing the limbs of the mouse. The heating plate is provided below the mouse fixing trough. , a temperature sensor is provided in the mouse fixation tank.
进一步的,所述头部固定环与控制器电气连接,所述头部固定环向控制器发送开关信号。Further, the head fixing ring is electrically connected to the controller, and the head fixing ring sends a switch signal to the controller.
进一步的,所述温度传感器与控制器电气连接,所述温度传感器用以检测小鼠体温并向控制器发送开关信号。Further, the temperature sensor is electrically connected to the controller, and the temperature sensor is used to detect the body temperature of the mouse and send a switch signal to the controller.
进一步的,所述固定台采用导温材料制成。Further, the fixed platform is made of thermally conductive material.
进一步的,所述固定台上表面覆盖保温材料。Furthermore, the upper surface of the fixing table is covered with thermal insulation material.
进一步的,所述头部固定环、固定夹和尾夹的内侧均设有软质材料。Furthermore, the inner sides of the head fixing ring, fixing clip and tail clip are all provided with soft materials.
本实用新型具有以下有益效果:The utility model has the following beneficial effects:
(1)本装置能有效对小鼠进行固定的同时,实现保温、保暖,降低因小鼠放疗过程中因麻醉体温降低导致的死亡发生率。(1) This device can effectively immobilize mice while maintaining heat and warmth, and reduce the incidence of death caused by lowering body temperature due to anesthesia during radiotherapy in mice.
(2)本装置采用温度传感器,在放疗过程中探测小鼠体温实现加热的自动化,防止小鼠体温过低或过高。(2) This device uses a temperature sensor to detect the mouse's body temperature during radiotherapy to automate heating and prevent the mouse's body temperature from being too low or too high.
(3)本装置采用多个小鼠固定槽,可同时固定加热多个小鼠,并且各位置可单独加热。(3) This device uses multiple mouse fixing slots, which can fix and heat multiple mice at the same time, and each position can be heated independently.
(4)头部固定环、固定夹和尾夹的内侧均设有软质材料,防止对小鼠造成伤害。(4) The inner sides of the head fixing ring, fixing clip and tail clip are all equipped with soft materials to prevent damage to mice.
附图说明Description of the drawings
为了更清楚地说明本实用新型实施例或现有技术中的技术方案,下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本实用新型的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动性的前提下,还可以根据这些附图获得其他的附图。In order to explain the embodiments of the present invention or the technical solutions in the prior art more clearly, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description These are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without exerting any creative effort.
图1是本实用新型一种可取暖的实验小鼠放疗固定装置的主视图。Figure 1 is a front view of a heating fixation device for experimental mouse radiotherapy according to the present invention.
附图标记:固定台1 加热片2 控制器3 电源4 小鼠固定槽5Reference signs: Fixed table 1 Heating plate 2 Controller 3 Power supply 4 Mouse fixing slot 5
突出部6 头部固定环7 固定夹8 尾夹9 温度传感器10Protrusion 6 Head fixing ring 7 Fixing clip 8 Tail clip 9 Temperature sensor 10
具体实施方式Detailed ways
下面将结合本实用新型实施例中的附图,对本实用新型实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本实用新型一部分实施例,而不是全部的实施例。基于本实用新型中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本实用新型保护的范围。The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only part of the embodiments of the present utility model, not all implementations. example. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts fall within the scope of protection of the present utility model.
在以下的描述中,涉及到“一些实施例”,其描述了所有可能实施例的子集,但是可以理解,“一些实施例”可以是所有可能实施例的相同子集或不同子集,并且可以在不冲突的情况下相互结合。In the following description, reference is made to "some embodiments" which describe a subset of all possible embodiments, but it is understood that "some embodiments" may be the same subset or a different subset of all possible embodiments, and Can be combined with each other without conflict.
除非另有定义,本文所使用的所有的技术和科学术语与属于本申请的技术领域的技术人员通常理解的含义相同。本文中所使用的术语只是为了描述本申请实施例的目的,不是旨在限制本申请。Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field to which this application belongs. The terms used herein are only for the purpose of describing the embodiments of the present application and are not intended to limit the present application.
图1是本实用新型一种可取暖的实验小鼠放疗固定装置的主视图。如图1所示本实用新型的一种可取暖的实验小鼠放疗固定装置,包括固定台1,固定台1底部安装有支撑脚。固定台1为长方体形状,且为中空结构,内部安装有加热片2,控制器3和电源4。Figure 1 is a front view of a heating fixation device for experimental mouse radiotherapy according to the present invention. As shown in Figure 1, the utility model provides a heating fixation device for radiotherapy for experimental mice, which includes a fixing table 1. The bottom of the fixing table 1 is equipped with supporting feet. The fixed platform 1 is in the shape of a rectangular parallelepiped and has a hollow structure, with a heating plate 2, a controller 3 and a power supply 4 installed inside.
在本实施例中,固定台1上表面并列设置有数个小鼠固定槽5,小鼠固定槽5为长方形,其高度低于固定台1上表面,小鼠固定槽5的顶端设置有放置小鼠头部的突出部6,突出部6上设有小鼠头部固定环7,小鼠固定槽5的底端设置有用以夹持小鼠尾巴的尾夹9,小鼠固定槽1的两侧设有固定小鼠四肢的固定夹8。In this embodiment, several mouse fixing slots 5 are arranged side by side on the upper surface of the fixing table 1. The mouse fixing slots 5 are rectangular, and their height is lower than the upper surface of the fixing table 1. The top of the mouse fixing slot 5 is provided with a small The protruding portion 6 of the mouse head is provided with a mouse head fixing ring 7. The bottom end of the mouse fixing groove 5 is provided with a tail clip 9 for holding the mouse tail. Both sides of the mouse fixing groove 1 are The side is provided with fixing clips 8 for fixing the limbs of the mouse.
在本实施例中,为了保护小鼠头部固定环7、固定夹8和尾夹9的内侧均设有软质材料,防止对小鼠造成伤害。In this embodiment, in order to protect the mice, soft materials are provided on the inside of the fixing ring 7, the fixing clip 8, and the tail clip 9 to prevent damage to the mice.
在本实施例中,加热片2设于小鼠固定槽5下方,为了便于加热片2加热,固定台1采用导热材料,同时为了在加热过程中保证温度不会流失,固定台1的上表面覆盖有保温材料。In this embodiment, the heating piece 2 is located below the mouse fixing slot 5. In order to facilitate the heating of the heating piece 2, the fixing table 1 is made of thermally conductive material. At the same time, in order to ensure that the temperature will not be lost during the heating process, the upper surface of the fixing table 1 Covered with insulation material.
在本发明的一个实施例中,加热片3可以是一层或多层电加热丝构成,加热片与2控制器3,电源4采用电气连接。电源4采用电池和/或充电器为其提供电能,控制器3控制加热片的启动或关闭,也可以控制加热片2的加热温度。控制器3与加热片2采用并联连接,可以全部或部分控制加热片2的温度和启停。In one embodiment of the present invention, the heating sheet 3 may be composed of one or more layers of electric heating wires, and the heating sheet is electrically connected to the controller 3 and the power supply 4 . The power supply 4 uses a battery and/or charger to provide electric energy, and the controller 3 controls the startup or shutdown of the heating piece, and can also control the heating temperature of the heating piece 2. The controller 3 and the heating piece 2 are connected in parallel and can fully or partially control the temperature and start and stop of the heating piece 2.
在本发明的一个实施例中,头部固定环8与控制器3电气连接,头部固定环8向控制器3发送开关信号,这样实验人员在将小鼠固定在小鼠固定槽5之后,关闭头部固定环7,就可以启动该路加热片2进行加热,当结束放疗之后,打开头部固定环7,就可以关闭该路加热片2。In one embodiment of the present invention, the head fixing ring 8 is electrically connected to the controller 3, and the head fixing ring 8 sends a switch signal to the controller 3, so that after the experimenter fixes the mouse in the mouse fixing slot 5, By closing the head fixing ring 7, the heating piece 2 can be started for heating. After the radiotherapy is completed, the head fixing ring 7 is opened, and the heating piece 2 can be turned off.
在本发明的另一个实施例中,小鼠固定槽6内设有温度传感器10,温度传感器10与控制器3电气连接,温度传感器10用以检测小鼠体温并向控制器3发送开关信号。在实验过程中,温度传感器10实时检测小鼠体温,防止小鼠体温过低或过高,有效控制加热的启停和温度。In another embodiment of the present invention, a temperature sensor 10 is provided in the mouse fixing tank 6. The temperature sensor 10 is electrically connected to the controller 3. The temperature sensor 10 is used to detect the body temperature of the mouse and send a switch signal to the controller 3. During the experiment, the temperature sensor 10 detects the mouse's body temperature in real time to prevent the mouse's body temperature from being too low or too high, and effectively controls the start and stop of heating and the temperature.
尽管上面已经示出和描述了本实用新型的实施例,可以理解的是,上述实施例是示例性的,不能理解为对本实用新型的限制,本领域的普通技术人员在本实用新型的范围内可以对上述实施例进行变化、修改、替换和变型。凡在本实用新型的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本实用新型的保护范围之内。Although the embodiments of the present invention have been shown and described above, it can be understood that the above-mentioned embodiments are illustrative and cannot be construed as limitations of the present invention. Those of ordinary skill in the art are within the scope of the present invention. Changes, modifications, substitutions and variations may be made to the above-described embodiments. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model shall be included in the protection scope of the present utility model.
Claims (5)
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CN202222379796.9U CN219896005U (en) | 2022-09-07 | 2022-09-07 | Experimental mouse radiotherapy fixing device that can get warm |
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