CN219846937U - Electrode for animal brain operation - Google Patents
Electrode for animal brain operation Download PDFInfo
- Publication number
- CN219846937U CN219846937U CN202223599649.9U CN202223599649U CN219846937U CN 219846937 U CN219846937 U CN 219846937U CN 202223599649 U CN202223599649 U CN 202223599649U CN 219846937 U CN219846937 U CN 219846937U
- Authority
- CN
- China
- Prior art keywords
- electrode
- utility
- model
- brain
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000004556 brain Anatomy 0.000 title claims abstract description 19
- 241001465754 Metazoa Species 0.000 title claims abstract description 15
- 238000001356 surgical procedure Methods 0.000 claims abstract description 9
- 229940057838 polyethylene glycol 4000 Drugs 0.000 claims 1
- 229920001030 Polyethylene Glycol 4000 Polymers 0.000 abstract description 5
- 230000008901 benefit Effects 0.000 abstract description 2
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract description 2
- 230000036541 health Effects 0.000 abstract description 2
- 238000003384 imaging method Methods 0.000 description 3
- 230000005284 excitation Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000002610 neuroimaging Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000002739 subcortical effect Effects 0.000 description 1
Landscapes
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
The utility model relates to an electrode for brain surgery of animals, which is characterized in that 4 electrodes are stuck on the outer wall of GRIN lens equidistantly by PEG4000 and fixed by a wire fixing device. An advantage of embodiments of the present utility model is that electrodes are attached to GRIN lenses by PEG 4000. Therefore, the electrode is inserted into the brain of the animal in time, the material can not influence the health of the animal, and simultaneously, the photoelectric signal can be synchronously obtained during operation.
Description
Technical Field
The utility model relates to the technical field of animal surgery, in particular to an electrode for animal brain surgery.
Background
In research on the brain, high resolution in vivo optical deep brain imaging has been a great challenge. Buried brain structures can be imaged early on by gradient index (GRIN) lenses embedded in the brain. But imaging is limited to the superficial brain region due to the severe attenuation in depth of the excitation and emission photons caused by tissue scattering. Although longer excitation wavelengths or red-shifted fluorescent markers can mitigate the scattering effect, imaging depth is still limited to 0.1-1mm in the mouse brain and imaging quality can decrease rapidly with increasing depth. To image deeper subcortical structures beyond this limit, a micro-scope has been used that relies on implantation of miniature gradient index (gradient refractive index lens, GRIN lens) lenses in the brain.
However, when the GRIN lens operation is performed, it is difficult to combine the photoelectric technologies in the prior art, mainly because the GRIN lens is too small and the electrode is too thin, and no suitable material is used to tightly attach the electrode to the GRIN lens, so as to analyze the photoelectric signals of the same micro brain area, and thus it is difficult to perform the photoelectric recording synchronization in the prior art.
Disclosure of Invention
The embodiment of the utility model aims to provide an electrode for animal brain surgery, which has a simple structure. The electrodes are stuck on the lens through special materials, so that the photoelectric signals can be obtained simultaneously during brain surgery of the animal at the other side.
In order to achieve the purpose of the embodiment, the embodiment of the utility model provides an electrode for brain surgery of animals, wherein 4 electrodes are stuck on the outer wall of GRIN lens equidistantly by PEG4000 and fixed by a wire fixing device.
For better fixing the electrode wire, a groove for fixing the electrode wire is arranged on the inner diameter of the wire fixing device.
An advantage of embodiments of the present utility model is that electrodes are attached to GRIN lenses by PEG 4000. Therefore, the electrode is inserted into the brain of the animal in time, the material can not influence the health of the animal, and simultaneously, the photoelectric signal can be synchronously obtained during operation.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings that are needed in the description of the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present utility model, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic view of an electrode structure for brain surgery of an animal according to an embodiment of the present utility model.
Fig. 2 is a schematic diagram of a wire holder according to an embodiment of the present utility model.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
The electrode for brain surgery of animals provided by the embodiment of the utility model is shown in fig. 1, and 4 electrodes 1 (one of which is not shown) are equidistantly adhered to the outer wall of the GRIN lens2 through PEG 4000. The rear end of the electrode is fixed by a wire fixing device 3. As shown in fig. 2, the inner diameter of the wire holder 3 has a shape corresponding to GRIN lens2, and grooves are provided at positions of 4 corresponding electrodes for facilitating clamping of the electrodes.
The foregoing description of the embodiments has been provided for the purpose of illustrating the general principles of the utility model, and is not meant to limit the scope of the utility model, but to limit the utility model to the particular embodiments, and any modifications, equivalents, improvements, etc. that fall within the spirit and principles of the utility model are intended to be included within the scope of the utility model. Meanwhile, the parts in the drawings of the embodiments, which have the same functions and principles as those of the prior art, are not described herein again.
Claims (1)
1. An electrode for brain surgery in an animal, characterized by: 4 electrodes are stuck on the outer wall of the gradient refractive index lens at equal intervals by polyethylene glycol 4000 and are fixed by a wire fixing device with a fixed electrode wire groove on the inner diameter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223599649.9U CN219846937U (en) | 2022-12-29 | 2022-12-29 | Electrode for animal brain operation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223599649.9U CN219846937U (en) | 2022-12-29 | 2022-12-29 | Electrode for animal brain operation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219846937U true CN219846937U (en) | 2023-10-20 |
Family
ID=88319689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223599649.9U Active CN219846937U (en) | 2022-12-29 | 2022-12-29 | Electrode for animal brain operation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219846937U (en) |
-
2022
- 2022-12-29 CN CN202223599649.9U patent/CN219846937U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230363646A1 (en) | System and method for large field of view, single cell analysis | |
| Kerr et al. | Functional imaging in freely moving animals | |
| US9036970B2 (en) | Method and device for diffuse excitation in imaging | |
| Ohta et al. | Implantable microimaging device for observing brain activities of rodents | |
| CN101485558B (en) | Single-optical fiber multiphoton fluorescence scanning endoscope | |
| Li et al. | A biological global positioning system: considerations for tracking stem cell behaviors in the whole body | |
| CN106913309B (en) | Based on single all -fiber endoscopic OCT probe for drawing wimble structure | |
| CN219846937U (en) | Electrode for animal brain operation | |
| WO2012124092A1 (en) | Microimaging probe and manufacturing method thereof | |
| EP2530501A2 (en) | Plastic scintillator, and scintillation detector and medical diagnostic imaging equipment using same | |
| CN103149678B (en) | Miniature bifocus objective lens probe | |
| CN219846936U (en) | A clamp straight ware for animal surgery | |
| CN217338836U (en) | High-resolution optical scanning probe with quickly replaceable protective sleeve | |
| Ota et al. | Fast scanning high optical invariant two-photon microscopy for monitoring a large neural network activity with cellular resolution | |
| JP6463218B2 (en) | Laser therapy apparatus and photodynamic therapy apparatus for esophageal cancer | |
| CN101511263B (en) | Optical tomography measurement using an adapted brim for the receiving volume | |
| Ng et al. | A Complementary Metal–Oxide–Semiconductor Image Sensor for On-Chip in Vitro and in Vivo Imaging of the Mouse Hippocampus | |
| Cooke et al. | Computational Cannula Microscopy: Utilizing a Simple Glass Needle for Imaging | |
| CN113391438A (en) | Multi-plane microscopic imaging system and imaging method based on micro lens | |
| Kim et al. | Computational Cannula Microscopy: Fluorescent Imaging Through Ultra-Thin Glass Needle | |
| US20120257203A1 (en) | Apparatus and method for light emission detection for in-depth imaging of turbid media | |
| Kim et al. | Deep Tissue Fluorescent Imaging via Computational Cannula Microscopy | |
| CN217611027U (en) | Protective sleeve, implanted lens and living body brain imaging device | |
| WO2024108517A1 (en) | Method and system for fluorescence synchronous imaging in deep brain region and whole-brain cortex scale | |
| Rivera et al. | Multiphoton endoscopes for in vivo imaging of unstained tissues |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |