CN219628576U - Mouse metabolism cage capable of collecting urine aseptically - Google Patents
Mouse metabolism cage capable of collecting urine aseptically Download PDFInfo
- Publication number
- CN219628576U CN219628576U CN202320642706.2U CN202320642706U CN219628576U CN 219628576 U CN219628576 U CN 219628576U CN 202320642706 U CN202320642706 U CN 202320642706U CN 219628576 U CN219628576 U CN 219628576U
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- Prior art keywords
- cage
- cage body
- mouse
- trough
- frame
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- 210000002700 urine Anatomy 0.000 title claims abstract description 48
- 230000004060 metabolic process Effects 0.000 title claims abstract description 22
- 241000699666 Mus <mouse, genus> Species 0.000 claims abstract description 35
- 241000699670 Mus sp. Species 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
- 238000005070 sampling Methods 0.000 claims description 8
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 abstract description 3
- 238000002474 experimental method Methods 0.000 abstract description 3
- 210000003608 fece Anatomy 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 4
- 238000010171 animal model Methods 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010172 mouse model Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The utility model relates to the technical field of animal experiment appliances, in particular to a mouse metabolism cage for aseptically collecting urine, which comprises a frame, wherein a cage body and a cone bucket are arranged on the frame, the cage body is internally used for feeding experimental mice, the cone bucket is positioned right below the cage body, the bottom of the cone bucket is connected with a collecting bag, the collecting bag is used for containing urine excreted by the mice, a detachable filter screen is further arranged on the frame, the filter screen is positioned below the cage body and at the top end of the cone bucket, and the cone bucket and the filter screen cover the whole bottom surface of the cage body. The utility model is helpful for solving the problems that the feces are easy to accumulate on the urine discharge path and the filter screen is inconvenient to clean in the existing structure.
Description
Technical Field
The utility model relates to the technical field of animal experiment appliances, in particular to a mouse metabolism cage for aseptically collecting urine.
Background
The method of directly collecting animal metabolites by means of a fecal and urinary separation device is called a metabolism cage method. The metabolism cage is used for collecting urine and excrement naturally discharged by experimental animals, is a closed rearing cage which is specially designed for collecting various excretions of the experimental animals, and can also collect carbon dioxide exhaled by the experimental animals. The metabolism cage of the laboratory mouse is a raising cage special for collecting excreta of the laboratory mouse, is used for in-vivo metabolism experiments of the laboratory mouse, can provide comfortable living environment for the laboratory mouse, can quantify drinking water and food of the laboratory mouse, and allows the laboratory mouse to naturally metabolize, and the separation device of the metabolism cage can separate excrement and urine of the laboratory mouse, so that in-vivo metabolism researches of various medicines, nutrient substances and the like can be carried out.
At present, the metabolism cage of some mice sets up the filter screen in the inside lower extreme region that is close to of awl fill, when this kind of structure makes mouse top excrete excrement and urine, excrement and urine most can drop to awl fill inclined plane, then along with awl fill inclined plane gliding and pile up to filter screen and awl fill internal surface junction, then the urine of mouse is discharged down along awl fill inclined plane when, the high probability can be with originally piled up excrement and urine contact, can produce fine and broken bits impurity after flushing to this excrement and urine and discharge into the collection bag along with the urine, influence sample collection quality, in addition, the sunken filter screen structure need stretch into inside cleanness or dismouting when clean, it is relatively inconvenient. In addition, the current mouse metabolism cage cone hopper is not connected with a specific container, so that a user collects urine by using a wide-mouth bottle, the structure enables the collected urine to be widely contacted with air and then react with bacteria and microorganisms in the air, and the urine is polluted with high probability, so that the sample collection quality is influenced, and various research results are influenced.
Disclosure of Invention
The utility model mainly aims to provide a mouse metabolism cage for aseptically collecting urine, which is beneficial to solving the problems that when the existing structure collects long-term urine, urine can be exposed in the air for too long, so that components of urine of certain model mice are polluted or decomposed by bacteria in the air, excrement is easy to accumulate on a urine discharge path, and a filter screen is inconvenient to clean.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
the utility model provides a mouse metabolism cage of urine is collected in aseptic, includes the frame, is equipped with the cage body and the awl fights in the frame, is used for raising experimental mouse in the cage body, and the awl fights to be located the cage body under, and the awl fights the bottom to be connected with and collect the bag, and the collection bag is used for accomodating the excretory urine of mouse, still is equipped with detachable filter screen in the frame, and the filter screen is located the cage body below and is located the awl fights the top, and the awl fights and the filter screen covers the whole bottom surface of the cage body.
On the basis of the technical scheme, the top of the collecting bag is provided with a threaded joint, the bottom of the cone is provided with a discharge pipe, and the threaded joint is in threaded connection with the discharge pipe.
On the basis of the technical scheme, the bottom of the collecting bag is provided with a sampling tube, and the sampling tube is provided with a switch valve.
On the basis of the technical scheme, the food groove and the water groove are formed in the cage body, and the water groove is connected with the water storage bottle.
On the basis of the technical scheme, the cage body and/or the cone bucket are/is detachably connected with the frame.
On the basis of the technical scheme, the cage body, the filter screen and the cone hopper are made of stainless steel.
On the basis of the technical scheme, the feeding trough and the water trough are arranged on the outer side of the front face of the cage body, the inner ends of the feeding trough and the water trough are fixedly connected with the side wall of the cage body, and an opening is formed in the connecting position for the head of the mouse to penetrate into the feeding trough and the water trough for feeding.
On the basis of the technical scheme, the feeding trough and the water trough are detachably connected with the cage body.
On the basis of the technical scheme, the baffle structure is arranged at the bottom of the inner side of the water tank and used for preventing water in the water tank from entering the cage body and penetrating into the collecting bag below.
On the basis of the technical scheme, the top of the cone hopper is provided with an extension clamping table for being clamped with the frame.
On the basis of the technical scheme, the bottom of the frame is provided with the travelling wheels.
The technical scheme at least comprises the following beneficial effects:
according to the utility model, the filter screen is arranged below the cage body and is positioned at the top end of the cone hopper, the cone hopper and the filter screen cover the whole bottom surface of the cage body, so that the excreted excrement of a mouse can be intercepted by the filter screen in time, and the excrement is accumulated in each area of the filter screen without difference, which is helpful for avoiding the excrement from being accumulated at the joint of the filter screen and the inner surface of the cone hopper in a concentrated manner, thereby reducing the probability of urine discharge contacting the originally accumulated excrement. The bottom of the cone hopper is directly connected with the collecting bag, so that the contact surface and time between urine and air are reduced, and bacterial breeding and microbial reaction are reduced.
Additional features and advantages of the utility model will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the utility model. The objectives and other advantages of the utility model may be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.
Drawings
FIG. 1 is a simplified perspective view of a mouse metabolism cage according to an embodiment;
FIG. 2 is a cross-sectional view of FIG. 1;
FIG. 3 is a schematic perspective view of the cone of FIG. 1;
fig. 4 is a schematic perspective view of a cone in another embodiment.
The drawing is marked: 1. a frame; 2. a cage body; 21. a trough; 22. a water tank; 23. a water storage bottle; 3. a cone bucket; 31. a discharge pipe; 32. an extension clamping table; 4. a collection bag; 41. a threaded joint; 42. a sampling tube; 43. a switch valve; 5. and (5) a filter screen.
Detailed Description
The utility model will be described in further detail with reference to the drawings and the specific examples.
Example 1:
referring to fig. 1-3, the embodiment discloses a mouse metabolism cage for aseptically collecting urine, which comprises a frame 1, a cage body 2, a cone bucket 3, a filter screen 5 and a collecting bag 4.
The frame 1 is made of metal section bars and mainly plays a bearing and supporting role.
The inside of the frame 1 is welded with a cone bucket 3, the cone bucket 3 is of a square-round funnel structure, the bottom of the cone bucket 3 is provided with a vertical discharge pipe 31, and the cone bucket 3 is used for guiding urine of a mouse to travel downwards into a collecting bag 4 below.
The top of the cone hopper 3 is clamped with a horizontal filter screen 5, and the filter screen 5 is made of a 30-mesh stainless steel mesh plate and mainly plays a role in separating mouse faeces and urine. Because the filter screen 5 is horizontally arranged, when the mouse irregularly discharges the excrement above, each region of the filter screen 5 can be directly collected without difference, the situation of excessively concentrated accumulation in certain regions, particularly the region at the joint of the filter screen 5 and the cone bucket 3, can not be generated, and thus the probability of contacting the excrement in the subsequent urine downward discharge can be reduced.
The cage body 2 is made of stainless steel net plates, is provided with an opening and closing door plate, a feeding trough 21 and a water trough 22, wherein the water trough 22 is connected with a water storage bottle 23 for daily feeding of mice. In this embodiment, the trough 21 and the water trough 22 are fixedly arranged on the front side wall of the cage body 1, and an opening is arranged at the joint between the inner sides of the trough 21 and the water trough 22 and the cage body 1, so that the heads of the mice can be inserted into the trough 21 and the water trough 22 to eat. In other embodiments, the trough 21 and the trough 22 may be connected to the cage 1 by a detachable structure, such as a hook structure.
In order to prevent water in the water tank 22 from flowing inwards into the cage body 1 and penetrating into the lower collecting bag 4 to influence the accuracy of urine sample collection, a baffle is arranged at the bottom of the inner side of the water tank 22.
It should be noted that, cone bucket 3 and filter screen 5 cover the whole bottom surface of cage body 2 to ensure urine collection integrality.
The awl fill 3 bottom is connected with collecting bag 4, and collecting bag 4 is used for accomodating the excretory urine of mouse, and collecting bag 4 top is equipped with screwed joint 41, and screwed joint 41 has the internal thread structure for with the external screw thread connection of discharge tube 31 bottom, through threaded connection's mode for collecting bag 4's installation is more firm reliable, and the dismouting is convenient. Further, the bottom of the collecting bag 4 is provided with a sampling tube 42, and the sampling tube 42 is provided with a switch valve 43, so that the subsequent urine sampling is facilitated.
Example 2:
the main difference between this embodiment and embodiment 1 is that: in combination with fig. 4, a group of extending clamping tables 32 are arranged at the top of the cone hopper 3, and the extending clamping tables 32 are directly clamped on the cross beam of the frame 1 from top to bottom when the cone hopper 3 is assembled, so that the assembly and disassembly are convenient.
Example 3:
on the basis of the embodiment 1, the bottom of the frame 1 is also provided with travelling wheels, in particular universal wheels with brake structures, which facilitate the carrying and moving of the equipment.
Example 4:
on the basis of the embodiment 1, a plurality of flange blocking strips are arranged on the inclined plane on the inner side of the cone bucket 3 and used for blocking and filtering fine impurities in the urine descending process of the inclined plane.
Example 5:
on the basis of embodiment 1, be equipped with helical blade structure on the inboard inclined plane of awl fill 3, helical blade is towards discharge tube 31, and this is at urine downstream in-process, and helical blade can play the guide effect, also plays the effect of increasing the resistance for the tiny impurity that is mingled with in the urine is intercepted and is adhered on the blade.
In other embodiments, a related agent may also be added to the collection bag 4 to prevent urine spoilage.
In other embodiments, the outside of the cage body 1 is provided with a light shielding cover body, the inner side of the cover body is provided with heat insulation cotton, the cover body can play a role in shielding light, the mice are prevented from being exposed under a bright light environment for a long time, normal body functions and metabolism conditions of the mice are influenced, the cover body can also play a role in heat insulation, comfortable temperature conditions are provided for the mice, and further urine collection accuracy is ensured.
The above embodiments are only for illustrating the technical solution of the present utility model, and are not limiting; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present utility model.
Claims (8)
1. The utility model provides a mouse metabolism cage of aseptic collection urine, a serial communication port, including frame (1), be equipped with cage body (2) and awl fight (3) on frame (1), be used for raising experimental mice in cage body (2), awl fight (3) are located cage body (2) under, awl fight (3) bottom is connected with collecting bag (4), collecting bag (4) are used for accomodating the excreted urine of mouse, still be equipped with detachable filter screen (5) on frame (1), filter screen (5) are located cage body (2) below and are located awl fight (3) top, awl fight (3) and filter screen (5) cover the whole bottom surface of cage body (2); the top of the collecting bag (4) is provided with a threaded joint (41), the bottom of the cone (3) is provided with a discharge pipe (31), and the threaded joint (41) is in threaded connection with the discharge pipe (31); the bottom of the collecting bag (4) is provided with a sampling tube (42), and the sampling tube (42) is provided with a switch valve (43).
2. The mouse metabolism cage for aseptically collecting urine according to claim 1, wherein the cage body (2) is provided with a feeding trough (21) and a water trough (22), and the water trough (22) is connected with a water storage bottle (23).
3. A mouse metabolizing cage for aseptically collecting urine according to claim 1, characterized in that the cage body (2) and/or the cone (3) are detachably connected to the frame (1).
4. The mouse metabolism cage for aseptically collecting urine according to claim 2, wherein the feeding trough (21) and the water trough (22) are arranged on the outer side of the front face of the cage body (2), the inner side ends of the feeding trough (21) and the water trough (22) are fixedly connected with the side wall of the cage body (2), and an opening is formed in the connecting position for the head of a mouse to penetrate into the feeding trough (21) and the water trough (22) for feeding.
5. A mouse metabolizing cage for aseptically collecting urine according to claim 2 or 4, characterized in that the trough (21) and the water trough (22) are detachably connected to the cage body (2).
6. A mouse metabolizing cage for aseptically collecting urine according to claim 4, characterized in that the inside bottom of the trough (22) is provided with a baffle structure for preventing water in the trough (22) from entering the cage body (2) and penetrating into the collecting bag (4) below.
7. A mouse metabolism cage for aseptically collecting urine according to claim 3, wherein the cone (3) is provided with an extension clamping table at the top for clamping with the frame (1).
8. A mouse metabolism cage for aseptically collecting urine according to claim 1, characterized in that the bottom of the frame (1) is provided with travelling wheels.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320642706.2U CN219628576U (en) | 2023-03-28 | 2023-03-28 | Mouse metabolism cage capable of collecting urine aseptically |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320642706.2U CN219628576U (en) | 2023-03-28 | 2023-03-28 | Mouse metabolism cage capable of collecting urine aseptically |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219628576U true CN219628576U (en) | 2023-09-05 |
Family
ID=87816199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320642706.2U Active CN219628576U (en) | 2023-03-28 | 2023-03-28 | Mouse metabolism cage capable of collecting urine aseptically |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219628576U (en) |
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2023
- 2023-03-28 CN CN202320642706.2U patent/CN219628576U/en active Active
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