CN219557652U - Intrathecal administration operation panel device for laboratory mice - Google Patents

Abstract

The utility model relates to an intrathecal administration console device for a laboratory mouse, which comprises a base, wherein a lifting console for fixing the laboratory mouse is arranged on the base, and a lifting and rotating placing disc for placing surgical instruments is arranged on the base. The surgical instrument placing device comprises a base, an operating table and a surgical instrument placing disc, wherein the surgical instrument placing disc is arranged above the operating table and can rotate and stretch to separate the surgical instrument from the operating table, so that the surgical instrument and the operating table can be ensured to be clean as much as possible in operation, and the postoperative infection probability is reduced; meanwhile, experimental operations can be carried out on different body types of experimental rats or mice on the same operation table.

Description

Intrathecal administration operation panel device for laboratory mice

Technical Field

The utility model relates to the field of animal experiment operations, in particular to an intrathecal administration operating table device for an experiment mouse.

Background

Intrathecal administration is an important technology for realizing targeted administration in experiments, and can be used for injecting medicines into subarachnoid space of experimental animals to directly act on central nervous system, so that the acting time is shortened and the medicine waste is reduced. Methods for achieving intrathecal administration include intrathecal injection administration and intrathecal catheter administration, the intrathecal injection administration being suitable for one-time administration experiments, or intrathecal administration in mice. And part of experiments need repeated administration for a plurality of times to reach a certain medicine concentration, the repeated administration can be carried out by adopting a sheath built-in tube, the sheath built-in tube is used for puncturing lumbar vertebra or atlas joints under the anesthesia of an experimental rat, then PE-10 and other types of catheters are placed into subarachnoid space for fixation, the technical means of intrathecal administration is realized through the placed catheters, and the experimental operation of one operation and multiple administration can be realized. Both intrathecal catheter and intrathecal injection need puncture through laboratory mouse intervertebral space, get into subarachnoid space, but laboratory mouse intervertebral space is narrow and small, consequently need its back crooked into certain radian, fully expose the intervertebral space, and especially the intrathecal catheter need cut skin muscle and put into subarachnoid space with the pipe, and consequently satisfy anesthesia and operation, the operation panel of position regulation is very important in experimental operation. The operation of the sheath built-in tube is required to be performed under the anesthesia state of the laboratory mice, and a gas anesthesia machine is generally adopted for maintaining anesthesia, and in actual operation, an anesthesia maintaining mask often falls down due to the operation and the posture change of the laboratory mice, so that the anesthesia effect is poor; in the experiment, the atlas occipital joint can be used for placing the tube according to the needs, and the lumbar vertebra can be used for placing the tube, and the two modes need to regulate the body position of an experimental mouse, so that the intervertebral space is fully exposed, and the puncture and the tube placement are convenient; and the sheath built-in tube is used for invasive surgery, so that aseptic operation is ensured in experiments, and the problems of death of experimental mice and the like caused by postoperative infection are prevented.

The prior art for intrathecal administration of laboratory mice includes intrathecal injection fixtures and intrathecal catheter fixtures. The existing intrathecal injection fixing device uses fixing nails and rubber bands to bind and fix rats, uses a cylinder to adjust the body position of the rats and assist in fixing, and adopts a fixed medicine bottle to continuously administer medicine (Zhang Haowen. A rat intrathecal injection fixing device [ P ]. CN210541925U, 2020-05-19.); the position of rats with different sizes is adjusted by adopting a fixed rod, a fixed clamp and a movable rod (Cheng Jingyi, cao Tao, he Jinyou, xu Jun and Fei Yunbo. A rat intrathecal injection positioning device [ P ]. CN208176609U, 2018-12-04.); or fixing the mice by adopting a circular ring clamp, and installing a convex plate on a rolling groove of a bottom plate to adjust the front and rear positions of the mouse, so that the intrathecal injection position and injection rate of the mice can be controlled (Li Jiahao, zhu Chunyan, lina, yang Jun, zhang Guoxin, chi Hongyu, tian Congmin. A mouse intrathecal injection device [ P ]. CN215937786U, 2022-03-04.); the fixing device adopts an arc-shaped plate and a front fixing column and a rear fixing column which are connected, the first spring, the second spring, the first sliding chute and the second sliding chute are used for fixing the heads of rats with different sizes, so that the back of the rat forms a certain radian under the support of the arc-shaped plate, and the puncture is convenient (Xiaozhi, qin Ying. A fixing device [ P ]. CN207785310U, 2018-08-31.) for intrathecal injection of an experimental rat.

The prior art has the following disadvantages: (1) An operation desk device realizes fixation of rats or mice with different sizes, and can not realize experimental operation of rats and mice in an experiment by using the same operation desk at the same time; (2) The stability and the tightness of the connection between the anesthesia mask and the head of the experimental mouse are not completely ensured; (3) Mainly focusing on the fixation of experimental rats or mice, and less on the cleaning of surgical instruments and operation table tops in the tube placing operation so as to realize aseptic operation requirements as much as possible and avoid the problems of postoperative infection and the like.

Disclosure of Invention

In view of the above, the utility model provides an intrathecal administration console device for laboratory mice, which aims to solve the problems in the prior art.

Specifically, the intrathecal administration console device for the laboratory mice comprises a base, wherein a lifting console for fixing the laboratory mice is arranged on the base, and a lifting and rotating placing disc for placing surgical instruments is arranged on the base.

On the basis of the scheme, the lifting device further comprises a first telescopic rod which is arranged on the base and used for being connected with the operating platform and used for lifting, and a second telescopic rod which is connected with the placing plate and used for lifting is further arranged on the first telescopic rod.

On the basis of the scheme, the second telescopic rod comprises a rotating part parallel to the operation table and used for adjusting the rotating angle of the placing tray and a telescopic part perpendicular to the rotating part and used for adjusting the height of the placing tray.

On the basis of the scheme, the operation panel comprises a table top for supporting the laboratory mice, a body position adjusting structure arranged on the table top and used for adjusting the body position of the laboratory mice, a first buckle arranged on the table top and used for fixing the heads of the laboratory mice, and a second buckle arranged on the table top and used for fixing the anesthetic masks.

On the basis of the scheme, the body position adjusting structure comprises a sliding groove which is arranged on the table top and used for guiding and limiting, and a U-shaped supporting piece which is matched with the sliding groove and used for supporting an experimental mouse.

On the basis of the scheme, the bottom of the U-shaped supporting piece is provided with a first sliding block matched with the sliding groove, and the U-shaped supporting piece matched with the sliding groove through the first sliding block can slide in the installation sliding groove.

On the basis of the scheme, the U-shaped supporting piece is integrally formed.

On the basis of the scheme, the body position adjusting structure comprises a sliding groove, a sliding block group and a supporting piece, wherein the sliding groove is arranged on the table top and used for guiding and limiting, the sliding block group is matched with the sliding groove for use, an adjusting rod for adjusting the height is arranged on the sliding block group, and the supporting piece is arranged on the adjusting rod and used for supporting an experimental mouse.

On the basis of the scheme, the body position adjusting structure is a supporting structure with a magnetic component at the bottom.

The device for the intrathecal administration operation table of the laboratory mice is simultaneously provided with the surgical instrument placing plate, the operation table and the base, so that the device can be folded and placed, the operation table and the instrument placing are ensured to be clean, and the space is saved; simultaneously, the same table top is designed to realize the tube placing operation of rats and mice by adopting sliding, stretching and the like, the tube placing operation can be performed through lumbar vertebra, and the tube placing operation efficiency can be improved through atlanto-occipital joint tube placing; the rubber buckle with adjustable size is also used for fixing the stability and the tightness of the connection of the head of the experimental mouse and the anesthesia maintenance mask, so that the anesthesia maintenance effect in the operation is ensured.

Drawings

Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the utility model. Also, like reference numerals are used to designate like parts throughout the figures. In the drawings:

FIG. 1 is a schematic view (side view) of the intrathecal administration console device for laboratory mice in example 1;

fig. 2 is a schematic structural view (in top view) of the console in embodiment 1;

fig. 3 is a schematic structural view (side view) of the U-shaped support member in embodiment 1;

fig. 4 is a schematic structural view of a U-shaped support member in embodiment 2;

fig. 5 is a schematic structural diagram of the U-shaped support member in embodiment 2 (test view).

Detailed Description

Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art. It should be noted that, without conflict, the embodiments of the present utility model and features of the embodiments may be combined with each other. The utility model will be described in detail below with reference to the drawings in connection with embodiments.

Example 1

As shown in fig. 1, an intrathecal administration console device for a laboratory mouse comprises a base 1, wherein an operation console 2 for fixing the laboratory mouse is arranged on the base 1, and a placing tray 3 for placing surgical instruments is arranged on the base 1.

As a specific embodiment, a first telescopic rod 1-1 for connecting with an operation table is arranged on the base 1, the first telescopic rod 1-1 is adjustable in height, a second telescopic rod 1-2 connected with the placing disc 3 is further arranged on the first telescopic rod 1-1, specifically, the second telescopic rod 1-2 comprises a rotating part 1-21 parallel to the operation table 3 and a telescopic part 1-22 perpendicular to the rotating part 1-21, the supporting part 1-21 is slightly longer than the end part (specific length is determined according to practice) of the operation table 2, and the rotating part 1-21 is connected with the placing disc 3 through the telescopic part 1-22 and is used for adjusting the height of the placing disc 3 and the angle relative to the operation table 2; in general, the placing tray 3 is located above the operating platform 2, the placing tray 3 rotates through the rotating part 1-21, so that the proper position can be conveniently adjusted in operation, and the first telescopic rod 1-1 and the second telescopic rod 1-2 can be reduced to the lowest position after the use is finished, the placing is convenient, and the space is saved.

When the surgical instrument placing plate is used, the surgical instrument placing plate 2 is positioned above the operating table 2 and can rotate and stretch, so that the surgical instrument is separated from the operating table 2, the surgical instrument and the operating table can be ensured to be clean as much as possible in operation, and the postoperative infection probability is reduced.

As another specific embodiment, in order to adjust the tightness of the connection part of the first telescopic rod 1-1 and the second telescopic rod 1-2, the connection part of the rotating part 1-21 and the first telescopic rod 1-1 is a knob or a screw adjuster, so that the overall position adjustment of the placement disc 3 and the second telescopic rod 1-2 is realized, and in use, the second telescopic rod 1-2 and the placement disc 3 can be integrally rotated to the front upper part or the left upper part and the right upper part of the operation table 2 and fixed, so that the position adjustment of the instrument placement disc 3 during the administration by atlanto-occipital joint sheath built-in tube or injection is realized.

As shown in fig. 2, as a specific embodiment, the operation table 2 includes a table top 2-1 for supporting a laboratory mouse, a posture adjusting structure 2-2 for adjusting the posture of the laboratory mouse is provided on the table top 2-1, a first buckle 2-3 for fixing the head of the laboratory mouse is provided on the table top 2-1, and a second buckle 2-4 for fixing an anesthetic mask is provided on the table top 2-1, specifically, one end of the table top 2-1 has an inclined surface 2-11, the inclined surface 2-11 is favorable for blood outflow and placement of a contaminated cotton swab in the experimental operation, the wound is kept clean, and the contamination is reduced, and the inclined surface is located at one end far from the second buckle 2-4.

As shown in figure 3, in order to facilitate the adjustment of the body position of the experimental mouse in the operation, the abdomen of the experimental mouse can be supported, the lumbar space is exposed, the lumbar catheterization or injection administration is convenient, and the body position during the atlanto-occipital joint catheterization or injection administration can be adjusted; the body position adjusting structure 2-2 comprises a sliding groove 2-21 arranged on the table top 2-1 and used for guiding and limiting, and a U-shaped supporting piece 2-22 matched with the sliding groove 2-21 and used for supporting a laboratory mouse, wherein a first sliding block 2-221 matched with the sliding groove 2-21 is arranged at the bottom of the U-shaped supporting piece 2-22, the U-shaped supporting piece 2-22 matched with the sliding groove 2-21 through the first sliding block 2-221 can slide in the installation sliding groove 2-21, and particularly, the top of the U-shaped supporting piece 2-22 is protruded and used for supporting the abdomen of the laboratory mouse to expose lumbar gaps; the U-shaped supporting pieces 2-22 with different protruding radians can be selected according to the size of the laboratory mice; the U-shaped supporting pieces 2-22 are of an integrated structure, the U-shaped supporting pieces 2-22 with different radians can be integrally taken down, the U-shaped supporting pieces 2-22 with larger radians can be used for rats, the U-shaped supporting pieces 2-22 with smaller radians can be replaced by mice, and the radians of the U-shaped supporting pieces 2-22 are different but the sliding blocks 2-23 are the same; in order to achieve a better limiting effect, the opposite outer side faces of the U-shaped supporting pieces 2-22 are provided with first grooves 2-222 matched with edges of the sliding grooves 2-21, the edges of the sliding grooves 2-21 are clamped into the first grooves 2-222, and the first sliding blocks 2-221 slide in the sliding grooves 2-21.

As a specific embodiment, the first buckle 2-3 may be a rubber buckle with adjustable size, which is used for fixing the head of the laboratory mouse and limiting the movement of the head of the laboratory mouse during operation; in order to improve the adaptability to the fixing of the head of the experimental mice with different body types and sizes, the first buckle 2-3 is designed to be in a detachable mode, and is convenient to replace.

When the device is used, the second buckle 2-4 is used for fixing a hose of the anesthesia mask on the gas anesthesia machine, and the second buckle 2-4 adopts a rubber buckle with adjustable size, so that the mask is stable and is prevented from falling off in operation; the use of the first buckle 2-3 and the second buckle 2-4 realizes that the head of the laboratory mouse is connected with the anesthesia maintenance mask in stability and tightness.

When the intrathecal administration operation table device for the laboratory mice is used, during operation, the first telescopic rod 1-1 is adjusted to a proper position and fixed, the second telescopic rod 1-2 is adjusted to a proper position and fixed, after gas inhalation anesthesia, the maintenance anesthesia mask is quickly fixed on the second buckle 2-4, the prone position of the laboratory mice after anesthesia is positioned on the operation table 2, the head is quickly fixed by the first buckle 2-3, so that the connection of the laboratory mice and the maintenance anesthesia mask is stable and airtight, and then the first sliding block 2-221 and the U-shaped supporting piece 2-22 are adjusted through the sliding groove 2-21, so that the spine of the laboratory mice is supported to be arc-shaped at a proper supporting position, the intervertebral space is fully exposed, and the intrathecal tube or injection administration is conveniently carried out through lumbar vertebra/atlas occipital joint; after the position has been adjusted, the necessary instruments and medicines are prepared and placed on the placement tray 3.

Example 2

As shown in fig. 4-5, according to another specific embodiment of the intrathecal administration console device for laboratory mice in example 1, a body position adjusting structure 2-2 is provided, and in order to facilitate the adjustment of the height of the body position adjusting structure 2-2, the body position adjusting structure 2-2 includes a chute 2-21 provided on the table top 2-1 for guiding and limiting, a slider group 2-23 cooperating with the chute 2-21, an adjusting rod 2-24 provided on the slider group 2-23 for adjusting the height, and a support member 2-25 provided on the adjusting rod 2-24 for supporting the laboratory mice; the sliding block group 2-23 comprises two second sliding blocks 2-231 which are oppositely arranged, and second grooves 2-2311 matched with the edges of the sliding grooves 2-21 are formed in the opposite outer side surfaces of the two second sliding blocks 2-231; the adjusting rods 2-24 can be adjusted back and forth and up and down according to the body positions required by the laboratory rats with different body types; the supporting pieces 2-25 are arc-shaped structures, the radian of each supporting piece is adjustable, and the protruding parts of the supporting pieces face upwards.

Example 3

According to the intrathecal administration console device for laboratory mice in example 1, this embodiment provides another specific embodiment of the posture adjustment structure 2-2, in order to simplify the structure, the posture adjustment structure 2-2 is a support structure with a magnetic component at the bottom, and can be moved and fixed by a magnetic manner, without setting a chute, and the front-back movement and fixation of the posture adjustment structure 2-2 on the table top 2-1 can be realized by means of a magnetic block at a corresponding position on the back of the console 2.

The intrathecal administration operation table device for the laboratory mice is simultaneously provided with the surgical instrument base 1, the operation table 2 and the placing plate 3, so that the operation table 2 and the instruments can be folded and placed, the placing cleanness of the operation table is ensured, and the space is saved; simultaneously, the same table top is designed to realize the tube placing operation of rats and mice by adopting sliding, stretching and the like, the tube placing operation can be performed through lumbar vertebra, and the tube placing operation efficiency can be improved through atlanto-occipital joint tube placing; the rubber buckle with adjustable size is also used for fixing the stability and the tightness of the connection of the head of the experimental mouse and the anesthesia maintenance mask, so that the anesthesia maintenance effect in the operation is ensured.

It will be apparent to those skilled in the art that various modifications and variations can be made to the present utility model without departing from the spirit or scope of the utility model. Thus, it is intended that the present utility model also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.

Claims (8)

1. The utility model provides an operation panel device of dosing in laboratory mouse sheath, includes base (1), its characterized in that: a lifting operation table (2) for fixing a laboratory mouse is arranged on the base (1), and a lifting and rotating placing disc (3) for placing surgical instruments is arranged on the base (1);

the operation table (2) comprises a table top (2-1) for supporting the laboratory mice, a body position adjusting structure (2-2) arranged on the table top (2-1) and used for adjusting the body position of the laboratory mice, a first buckle (2-3) arranged on the table top (2-1) and used for fixing the heads of the laboratory mice, and a second buckle (2-4) arranged on the table top (2-1) and used for fixing the anesthetic masks.

2. Intrathecal administration console apparatus according to claim 1, characterized in that said posture adjustment structure (2-2) comprises a chute (2-21) provided on the table top (2-1) for guiding and limiting and a U-shaped support (2-22) for supporting the laboratory mouse in cooperation with the chute (2-21).

3. The intrathecal administration console apparatus for laboratory mice according to claim 2, wherein a first slider (2-221) is provided at the bottom of the U-shaped support member (2-22) for use with the chute (2-21), and the U-shaped support member (2-22) is slidably mounted in the chute (2-21) by the first slider (2-221) being engaged with the chute (2-21).

4. A laboratory mouse intrathecal administration console apparatus according to claim 2 or 3, wherein said U-shaped support member (2-22) is integrally formed.

5. The intrathecal administration console apparatus for laboratory mice according to claim 1, wherein the posture adjusting structure (2-2) comprises a chute (2-21) arranged on a table top (2-1) for guiding and limiting, a sliding block group (2-23) matched with the chute (2-21), an adjusting rod (2-24) arranged on the sliding block group (2-23) for adjusting the height, and a supporting piece (2-25) arranged on the adjusting rod (2-24) for supporting the laboratory mice.

6. The intrathecal administration console apparatus for laboratory mice according to claim 1, wherein said posture adjusting structure (2-2) is a supporting structure provided with a magnetic attraction member at the bottom.

7. The intrathecal administration console apparatus for laboratory mice according to claim 1, further comprising a first telescopic rod (1-1) for lifting and lowering provided on the base (1) for connection with the console (2), wherein a second telescopic rod (1-2) for lifting and lowering is further provided on the first telescopic rod (1-1) for connection with the placement tray (3).

8. The intrathecal administration console apparatus for laboratory mice according to claim 7, wherein said second telescopic rod (1-2) comprises a rotating portion (1-21) parallel to the console (2) for adjusting the rotation angle of the placement tray (3) and a telescopic portion (1-22) perpendicular to the rotating portion (1-21) for adjusting the height of the placement tray (3).