CN219518393U - Ceramic membrane filter device for filtering bovine serum - Google Patents
Ceramic membrane filter device for filtering bovine serum Download PDFInfo
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- CN219518393U CN219518393U CN202320314479.0U CN202320314479U CN219518393U CN 219518393 U CN219518393 U CN 219518393U CN 202320314479 U CN202320314479 U CN 202320314479U CN 219518393 U CN219518393 U CN 219518393U
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Abstract
The utility model discloses a ceramic membrane filter device for filtering bovine serum, which comprises: the device comprises a bracket, a centrifugal pump and a liquid storage cylinder, wherein a liquid inlet of the centrifugal pump is connected with a transfer pipe, and a liquid outlet of the centrifugal pump is connected with a liquid feeding pipe; one end of the liquid conveying pipe is connected with a liquid conveying three-way pipe, one end of the liquid conveying three-way pipe is connected with a flow pipe, one end of the flow pipe is fixedly connected with a membrane filtration tank, the bottom end of the membrane filtration tank is connected with a circulating pipe, one end of the circulating pipe is fixedly provided with a circulating three-way pipe, and the other end of the circulating three-way pipe is connected with a first circulating liquid inlet pipe; the outer peripheral surface of the membrane filtration tank, which is close to the top end, is communicated with a first circulating sampling tube, and the outer periphery of the first circulating sampling tube is communicated with a second circulating sampling tube. The utility model can sample the filtrate filtered during the filtration of the bovine serum raw material, can continuously filter the sampled filtrate when the sampled filtrate does not reach the standard, and can sample the residual liquid after the filtration.
Description
Technical Field
The utility model relates to the technical field of bovine serum filtration, in particular to a ceramic membrane filter device for filtering bovine serum.
Background
Bovine serum is the natural medium with the largest dosage in cell culture and is rich in nutrient components necessary for cell growth, and bacteria, bacterial endotoxin, mycoplasma and various immunoglobulins existing in the bovine serum are main factors affecting the quality of bovine serum products in the cell culture process.
In the prior art, a microfiltration method is generally adopted to remove microorganisms such as bacteria and mycoplasma in bovine serum, but because the microfiltration die has larger pore diameter, only the microorganisms such as bacteria, mould and mycoplasma in the serum can be removed, and immunoglobulin in the serum cannot be removed, so that the quality of bovine serum products can be influenced, in addition, in the process of filtering the bovine serum, the filtered filtrate cannot be sampled and detected, whether the filtered filtrate meets the qualification standard cannot be judged, and in the process of filtering the bovine serum, the bovine serum raw material cannot be sampled, so that whether the residual bovine serum raw material still contains the required substances which can be filtered can not be judged after the bovine serum raw material is filtered.
Disclosure of Invention
The utility model aims to provide a ceramic membrane filter device for filtering bovine serum, which is used for solving the problems that in the prior art, the filtered filtrate cannot be rapidly sampled when the bovine serum raw material is filtered, and the residual liquid after filtration cannot be sampled, so that whether required substances exist or not cannot be judged.
In order to achieve the above purpose, the embodiment of the present utility model adopts the following technical scheme: the utility model provides a ceramic membrane filter equipment that filtration bovine serum was used, includes the support, its characterized in that: the upper surface of the bracket is fixedly provided with a liquid storage cylinder, one side of the liquid storage cylinder is fixedly provided with a control cabinet on the upper surface of the bracket, the other side of the liquid storage cylinder is fixedly provided with a centrifugal pump on the upper surface of the bracket, the centrifugal pump is provided with a liquid inlet and a liquid outlet, the liquid inlet of the centrifugal pump is connected with a switching pipe, and the liquid outlet of the centrifugal pump is connected with a liquid feeding pipe; one end of the liquid conveying pipe is connected with a liquid conveying three-way pipe, one end of the liquid conveying three-way pipe is connected with a flow pipe, one end of the flow pipe is fixedly connected with a membrane filtration tank, the bottom end of the membrane filtration tank is connected with a circulating pipe, one end of the circulating pipe is fixedly provided with a circulating three-way pipe, the other end of the circulating three-way pipe is connected with a first circulating liquid inlet pipe, one end of the first circulating liquid inlet pipe is connected with the upper end of the liquid storage barrel and extends into the liquid storage barrel, and the bottom of the liquid storage barrel is provided with a liquid outlet pipe; a liquid return pipe is fixedly connected to one end of the switching pipe, a fourth opening valve is fixedly arranged at one end of the liquid return pipe, and the periphery of the liquid return pipe is communicated with one end of the liquid outlet pipe; the outer peripheral surface of the membrane filtration tank, which is close to the top end, is communicated with a first circulating sampling pipe connected with the membrane filtration tank through a first circulating sampling connecting pipe, one end of the first circulating sampling pipe is fixedly provided with a second opening valve, the other end of the first circulating sampling pipe is fixedly connected with a second circulating liquid inlet pipe, and one end of the second circulating liquid inlet pipe is connected with the upper end of the liquid storage barrel and extends into the liquid storage barrel; the right side that is located first circulation sampling connecting pipe is provided with the second circulation sampling pipe in the periphery intercommunication of first circulation sampling pipe, is fixedly provided with the third at the one end of second circulation sampling pipe and opens the valve, is provided with the second circulation sampling connecting pipe in the periphery surface intercommunication of second circulation sampling pipe, and the one end intercommunication of second circulation sampling connecting pipe sets up in the bottom periphery surface that is close to the membrane filtration jar.
Further, in the embodiment of the utility model, a first opening valve is fixedly arranged at the connection part of the switching pipe and the liquid return pipe; the first sampling circulation control valve is fixedly arranged at the joint of the first circulation sampling pipe and the second circulation liquid inlet pipe, and the second sampling circulation control valve is fixedly arranged at the joint of the second circulation sampling pipe and the first circulation sampling pipe.
Further, in the embodiment of the utility model, the other end of the liquid feeding three-way pipe is connected with a flow regulating valve, and the outer peripheral surface of the flow pipe is fixedly provided with a pressure gauge.
Further, in the embodiment of the utility model, a third circulating sampling pipe is arranged on the outer peripheral surface of the circulating pipe facing downwards, a pressure gauge is fixedly arranged on the outer peripheral surface of the circulating pipe above the third circulating sampling pipe, and one end of the circulating three-way pipe is connected with a flow regulating valve.
Further, in the embodiment of the utility model, the observation window is arranged at the periphery of one end, close to the first circulating sampling pipe, of the first circulating sampling connecting pipe, so that the flow condition of filtrate in the first circulating sampling connecting pipe can be checked by using the observation window.
Further, in the embodiment of the utility model, the top end of the liquid storage barrel is movably connected with a hinge plate through a hinge, and a handle is fixedly arranged on the upper surface of the hinge plate, so that the liquid storage barrel can be covered by the hinge plate.
The beneficial effects of the utility model are as follows: the utility model can filter the bovine serum raw material through the membrane filtration tank, thus obtaining the needed filtrate, periodically sampling and analyzing the filtrate through the first and second circulating sampling tubes, and judging whether to collect the filtrate flowing out of the first and second circulating sampling tubes according to the sampling and analyzing results; the hinge plate is rotationally connected with the feeding port of the liquid storage barrel through the hinge, so that when the bovine serum raw material is put into the liquid storage barrel, the hinge plate is not required to be removed, and the feed port of the liquid storage barrel can be conveniently and rapidly opened, so that the bovine serum raw material can be conveniently put into the liquid storage barrel.
Drawings
The utility model will be further described with reference to the drawings and examples.
FIG. 1 is a schematic view showing the overall structure of a ceramic membrane filtration device for filtering bovine serum according to an embodiment of the present utility model.
Fig. 2 is a schematic view of the overall structure in the other direction of fig. 1.
Fig. 3 is a schematic view of the structure of fig. 1 at another view angle.
10. Bracket 20, centrifugal pump 30 and liquid storage cylinder
40. Control cabinet 50, liquid feeding pipe 60 and liquid feeding three-way pipe
70. Flow tube 80, membrane filtration tank 90, circulation tube
100. Circulation tee 110, first circulation feed liquor pipe 120, hinge
130. Liquid outlet pipe 140, liquid return pipe 150 and first circulating sampling pipe
1501. First circulation sampling connecting pipe 160, second circulation sampling pipe 1601, second circulation sampling connecting pipe
170. Second circulation feed pipe 180, first sampling circulation control valve 1801, first opening valve
1802. Second opening valve 1803, third opening valve 1804, fourth opening valve
1805. Second sampling circulation control valve
190. Adapter tube 200, pressure gauge 2001 and third circulation sampling tube
Detailed Description
In order to make the objects, technical solutions, and advantages of the present utility model more apparent, the embodiments of the present utility model will be further described in detail with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are some, but not all, embodiments of the present utility model, are intended to be illustrative only and not limiting of the embodiments of the present utility model, and that all other embodiments obtained by persons of ordinary skill in the art without making any inventive effort are within the scope of the present utility model.
In the description of the present utility model, it should be noted that the terms "center," "middle," "upper," "lower," "left," "right," "inner," "outer," "top," "bottom," "side," "vertical," "horizontal," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate description of the present utility model and simplify the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "a," an, "" the first, "" the second, "" the third, "" the fourth, "" the fifth, "and the sixth" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.
For purposes of brevity and description, the principles of the embodiments are described primarily by reference to examples. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the embodiments. It will be apparent, however, to one of ordinary skill in the art that the embodiments may be practiced without limitation to these specific details. In some instances, well-known methods and structures have not been described in detail so as not to unnecessarily obscure the embodiments. In addition, all embodiments may be used in combination with each other.
As shown in fig. 1-3, the embodiment discloses a ceramic membrane filtering device for filtering bovine serum, which comprises a bracket 10, wherein a liquid storage cylinder 30 is fixedly arranged on the upper surface of the bracket 10, in the embodiment, the top end of the liquid storage cylinder 30 is movably connected with a hinge plate through a hinge 120, the upper surface of the hinge plate is fixedly provided with a handle, the liquid storage cylinder 30 can be covered by the hinge plate, one side of the liquid storage cylinder 30 is fixedly provided with a control cabinet 40 on the upper surface of the bracket 10, the other side of the liquid storage cylinder 30 is fixedly provided with a centrifugal pump 20 on the upper surface of the bracket 10, the centrifugal pump 20 is provided with a liquid inlet and a liquid outlet, the liquid inlet of the centrifugal pump 20 is connected with a transfer pipe 190, and the liquid outlet of the centrifugal pump 20 is connected with a liquid delivery pipe 50;
the liquid delivery pipe 50 has one end connected with a liquid delivery three-way pipe 60, one end connected with a flow pipe 70, as shown in fig. 1, the other end of the liquid delivery three-way pipe 60 is connected with a flow regulating valve, the outer peripheral surface of the flow pipe 70 is fixedly provided with a pressure gauge 200, one end of the flow pipe 70 is fixedly connected with a membrane filtration tank 80, concretely, in this embodiment, the membrane filtration tank 80 is a ceramic membrane filter, a ceramic composite membrane with a filtration precision of 0.06 μm is installed in the ceramic membrane filter, the bottom end of the membrane filtration tank 80 is connected with a circulation pipe 90, as shown in fig. 3, the outer peripheral surface of the circulation pipe 90 facing downwards is provided with a third circulation sampling pipe 2001, the outer peripheral surface of the circulation pipe 90 above the third circulation sampling pipe 2001 is fixedly provided with a pressure gauge 200, one end of the circulation three-way pipe 100 is fixedly provided with a flow regulating valve, the other end of the circulation three-way pipe 100 is connected with a first circulation liquid inlet pipe 110, the other end of the circulation three-way pipe 100 is connected with a liquid outlet 30, and the bottom of the liquid outlet 30 is connected with the upper end of the liquid storage 30 and the liquid storage 30 is arranged at the bottom of the storage 30. After the desired substances are filtered out from the bovine serum raw material by the third circulating sampling tube 2001, the remaining residual liquid is sampled, and it is determined by the detecting device whether or not the content of the desired substances that can be filtered out is still present in the remaining residual liquid.
As shown in fig. 1, a liquid return pipe 140 is fixedly connected to one end of the switching pipe 190, in this embodiment, a first opening valve 1801 is fixedly arranged at a connection position between the switching pipe 190 and the liquid return pipe 140, a fourth opening valve 1804 is fixedly arranged at one end of the liquid return pipe 140, and the periphery of the liquid return pipe 140 is communicated with one end of the liquid outlet pipe 130;
as shown in fig. 1-3, a first circulation sampling tube 150 connected to the membrane filtration tank 80 through a first circulation sampling connection tube 1501 is provided on the outer peripheral surface of the membrane filtration tank 80 near the top end, in this embodiment, as shown in fig. 1, an observation window is provided on the outer periphery of one end of the first circulation sampling connection tube 1501 near the first circulation sampling tube 150, the flow condition of the filtrate in the first circulation sampling connection tube 1501 can be checked by using the observation window, a second opening valve 1802 is fixedly provided at one end of the first circulation sampling tube 150, a second circulation liquid inlet tube 170 is fixedly connected to the other end of the first circulation sampling tube 150, in this embodiment, a first sampling circulation control valve 180 is fixedly provided at the connection point between the first circulation sampling tube 150 and the second circulation liquid inlet tube 170, a second sampling circulation control valve 1805 is fixedly provided at the connection point between the second circulation sampling tube 160 and the first circulation sampling tube 150, one end of the second circulation liquid inlet tube 170 is connected to the upper end of the liquid storage tube 30 and extends into the interior of the liquid storage tube 30;
the right side that is located first circulation sampling connection pipe 1501 is provided with second circulation sampling pipe 160 in the periphery intercommunication of first circulation sampling pipe 150, is fixedly provided with third opening valve 1803 in the one end of second circulation sampling pipe 160, is provided with second circulation sampling connection pipe 1601 in the periphery surface intercommunication of second circulation sampling pipe 160, and the one end intercommunication of second circulation sampling connection pipe 1601 sets up in the bottom periphery surface that is close to membrane filtration jar 80.
The bovine serum raw material can be filtered through the membrane filtration tank 80 so as to obtain the required filtrate, meanwhile, the filtrate is periodically sampled and analyzed through the first and second circulating sampling pipes 150 and 160, and whether the filtrate flowing out of the first and second circulating sampling pipes 150 and 160 is collected is judged according to the sampling and analyzing results; the hinge plate is rotatably connected with the feed port of the liquid storage barrel 30 through the hinge 120, so that when the bovine serum raw material is fed into the liquid storage barrel 30, the hinge plate can be conveniently and rapidly opened without being detached, and the feeding of the bovine serum raw material is facilitated.
The working principle of the utility model is as follows: first, the first sampling cycle control valve 180, the first opening valve 1801, the second opening valve 1802, the third opening valve 1803, the fourth opening valve 1804, and the second sampling cycle control valve 1805 are set to be in a closed state, and at this time, the initial state is set, and then the mixed bovine serum raw material is put into the reservoir 30.
In use, the first opening valve 1801, the second opening valve 1802 and the third opening valve 1803 are opened, the centrifugal pump 20 is started, the rest is kept in a closed state, the bovine serum raw material in the liquid storage barrel 30 flows through the liquid outlet pipe 130, the liquid return pipe 140, the transfer pipe 190, the liquid feeding pipe 50, the liquid feeding three-way pipe 60 and the flow pipe 70 and enters the membrane filtration tank 80, the bovine serum raw material is filtered through the membrane filtration tank 80, so as to generate required filtrate, at this time, the filtered filtrate in the membrane filtration tank 80 flows through the first circulation sampling connecting pipe 1501 and the second circulation sampling connecting pipe 1601 respectively, then flows into the first circulation sampling pipe 150 and the second circulation sampling pipe 160 respectively, finally flows to a filtrate storage component (not shown in the figure) arranged outside through the second opening valve 1802 and the third opening valve 1803 respectively, and after a period of operation, the filtrate flowing out of the second opening valve 1802 and the third opening valve 1803 is periodically subjected to sampling detection;
when the detection of the filtrate in the first and second circulation sampling pipes 150 and 160 is qualified, the filtered filtrate continues to flow to the filtrate storage assembly provided outside through the second and third opening valves 1802 and 1803, and the remaining residual liquid enters the circulation tee 100 along the circulation pipe 90, enters the storage tank 30 through the first circulation feed pipe 110, and repeats the above filtering steps;
when the filtrate in the first circulation sampling tube 150 is failed, the second opening valve 1802 is closed, the first sampling circulation control valve 180 is opened, the second sampling circulation control valve 1805 is kept closed, and the failed filtrate in the first circulation sampling tube 150 is re-flowed into the liquid storage tube 30 through the second circulation liquid inlet tube 170, and is continuously filtered through the membrane filtration tank 80.
When the filtrate in the second and first sampling tubes 160 and 150 are failed, the second and third opening valves 1802 and 1803 are closed, and the second and first sampling cycle control valves 1805 and 180 are opened, so that the filtrate in the second sampling tube 160 flows into the first sampling tube 150, and flows into the reservoir 30 again together with the filtrate in the first sampling tube 150 through the second circulating feed pipe 170.
At this time, the third sampling tube 2001 is used to sample and detect the residual liquid, so as to determine whether the residual liquid still contains the content of the required substances capable of being filtered, and when the content of the required substances capable of being filtered is not satisfied in the residual liquid, the centrifugal pump 20, the second sampling control valve 1805 and the first sampling control valve 180 are closed, and the fourth opening valve 1804 is opened, so that the residual liquid is discharged outwards through the fourth opening valve 1804.
While the foregoing describes illustrative embodiments of the present utility model so that those skilled in the art may understand the present utility model, the present utility model is not limited to the specific embodiments, and all applications and creations utilizing the inventive concepts are within the scope of the present utility model as long as the modifications are within the spirit and scope of the present utility model as defined and defined in the appended claims to those skilled in the art.
Claims (6)
1. The utility model provides a ceramic membrane filter equipment that filtration bovine serum was used, includes the support, its characterized in that: the upper surface of the bracket is fixedly provided with a liquid storage cylinder, one side of the liquid storage cylinder is fixedly provided with a control cabinet on the upper surface of the bracket, the other side of the liquid storage cylinder is fixedly provided with a centrifugal pump on the upper surface of the bracket, the centrifugal pump is provided with a liquid inlet and a liquid outlet, the liquid inlet of the centrifugal pump is connected with a switching pipe, and the liquid outlet of the centrifugal pump is connected with a liquid feeding pipe;
one end of the liquid conveying pipe is connected with a liquid conveying three-way pipe, one end of the liquid conveying three-way pipe is connected with a flow pipe, one end of the flow pipe is fixedly connected with a membrane filtration tank, the bottom end of the membrane filtration tank is connected with a circulating pipe, one end of the circulating pipe is fixedly provided with a circulating three-way pipe, the other end of the circulating three-way pipe is connected with a first circulating liquid inlet pipe, one end of the first circulating liquid inlet pipe is connected with the upper end of the liquid storage barrel and extends into the liquid storage barrel, and the bottom of the liquid storage barrel is provided with a liquid outlet pipe;
a liquid return pipe is fixedly connected to one end of the switching pipe, a fourth opening valve is fixedly arranged at one end of the liquid return pipe, and the periphery of the liquid return pipe is communicated with one end of the liquid outlet pipe;
the outer peripheral surface of the membrane filtration tank, which is close to the top end, is communicated with a first circulating sampling pipe connected with the membrane filtration tank through a first circulating sampling connecting pipe, one end of the first circulating sampling pipe is fixedly provided with a second opening valve, the other end of the first circulating sampling pipe is fixedly connected with a second circulating liquid inlet pipe, and one end of the second circulating liquid inlet pipe is connected with the upper end of the liquid storage barrel and extends into the liquid storage barrel;
the right side that is located first circulation sampling connecting pipe is provided with the second circulation sampling pipe in the periphery intercommunication of first circulation sampling pipe, is fixedly provided with the third at the one end of second circulation sampling pipe and opens the valve, is provided with the second circulation sampling connecting pipe in the periphery surface intercommunication of second circulation sampling pipe, and the one end intercommunication of second circulation sampling connecting pipe sets up in the bottom periphery surface that is close to the membrane filtration jar.
2. The ceramic membrane filtration device for filtering bovine serum according to claim 1, wherein a first opening valve is fixedly arranged at the joint of the transfer pipe and the liquid return pipe;
the first sampling circulation control valve is fixedly arranged at the joint of the first circulation sampling pipe and the second circulation liquid inlet pipe, and the second sampling circulation control valve is fixedly arranged at the joint of the second circulation sampling pipe and the first circulation sampling pipe.
3. The ceramic membrane filter for filtering bovine serum according to claim 1, wherein a flow rate regulating valve is connected to the other end of the liquid feeding three-way pipe, and a pressure gauge is fixedly arranged on the outer peripheral surface of the flow pipe.
4. The ceramic membrane filtration device for filtering bovine serum according to claim 1, wherein a third circulating sampling tube is arranged on the downward outer peripheral surface of the circulating tube, a pressure gauge is fixedly arranged on the outer peripheral surface of the circulating tube above the third circulating sampling tube, and a flow regulating valve is connected and arranged at one end of the circulating three-way tube.
5. The ceramic membrane filtration device for filtering bovine serum according to claim 1, wherein an observation window is provided on the outer periphery of the end of the first circulating sampling connection pipe close to the first circulating sampling pipe, and the flow condition of the filtrate in the first circulating sampling connection pipe can be checked by using the observation window.
6. The ceramic membrane filter for bovine serum filtration according to claim 5, wherein the top end of the liquid storage cylinder is movably connected with a hinge plate through a hinge, and a handle is fixedly arranged on the upper surface of the hinge plate, so that the liquid storage cylinder can be covered by the hinge plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320314479.0U CN219518393U (en) | 2023-02-24 | 2023-02-24 | Ceramic membrane filter device for filtering bovine serum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320314479.0U CN219518393U (en) | 2023-02-24 | 2023-02-24 | Ceramic membrane filter device for filtering bovine serum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219518393U true CN219518393U (en) | 2023-08-15 |
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ID=87581200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320314479.0U Active CN219518393U (en) | 2023-02-24 | 2023-02-24 | Ceramic membrane filter device for filtering bovine serum |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219518393U (en) |
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2023
- 2023-02-24 CN CN202320314479.0U patent/CN219518393U/en active Active
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