CN219507934U - Automatic equipment for single-cell printing - Google Patents
Automatic equipment for single-cell printing Download PDFInfo
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- CN219507934U CN219507934U CN202223196215.4U CN202223196215U CN219507934U CN 219507934 U CN219507934 U CN 219507934U CN 202223196215 U CN202223196215 U CN 202223196215U CN 219507934 U CN219507934 U CN 219507934U
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P70/00—Climate change mitigation technologies in the production process for final industrial or consumer products
- Y02P70/50—Manufacturing or production processes characterised by the final manufactured product
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Abstract
The utility model discloses an automatic device for single-cell printing, which has the technical scheme that the automatic device comprises a machine body, wherein a printing cavity is formed on the machine body, a printing mechanism is arranged in the printing cavity, a fixing seat is further arranged in the printing cavity and used for placing a cell pore plate, a limiting mechanism and a moving mechanism are further arranged on the fixing seat, and the moving mechanism is used for controlling the limiting mechanism to move along a positioning seat and fix the cell pore plate. The utility model has the effect of centering and positioning cell pore plates with different specifications by adjusting the position of the limiting mechanism through the moving mechanism.
Description
Technical Field
The utility model relates to the technical field of cell printing equipment, in particular to automation equipment for single-cell printing.
Background
With the rapid development of biotechnology, more and more novel biotechnology is innovated and developed, and new technical content, namely cell printing technology, is also extended. Current cell printing techniques are broadly divided into: the inkjet cell printing, micro-extrusion cell printing, laser direct-writing cell printing, stereolithography cell printing and sound wave driven cell printing technologies find that when the micro-extrusion cell printing is used for printing cells, the conditions of cell dispersion and low survival rate are not easy to occur in actual application, and research on the field of micro-extrusion cell printing is concentrated.
The existing bulletin number is: chinese patent CN103333853B discloses a cell printing method and system, comprising: s1: the micro-jets are inserted into the desired cell suspension. S2: a micro-displacement reciprocation mechanism is used to perform a predetermined cell suction drive on the micro-nozzle to aspirate a number of cells and assemble a cell printing sequence. S3: the cells are arranged in close-packed single cell columns in the micro-jets by performing a predetermined cell-focusing drive on the micro-jets using a micro-displacement reciprocating mechanism. S4: the microjet is moved to a desired printing position and a predetermined cell ejection drive is performed on the microjet using a microdisplacement reciprocating mechanism to eject cells in sequence at the printing position. The sucking and printing operation of various cells is realized by using the same micro-jet tube.
Although the above technical scheme realizes the printing of cells, for the whole equipment controlled by the system, as the system intelligently controls the micro-nozzles to suck and print the cells, the cells are initially placed in the cell pore plate, and the whole system belongs to the same space coordinate system, the movement track of the system controls the micro-nozzles to move based on the position of the cell pore plate, so that the cell pore plate is required to keep a stable position in the space coordinate system, and the micro-nozzles can be sucked and printed quickly and accurately under the control of the system, however, in the existing printing equipment, the cell pore plate may not be in the middle position of the space coordinate system due to the deviation of the size of the cell pore plate when the cell pore plate is placed, so that the system is required to adjust the position of the micro-nozzles in time when the cell printing is performed, and the automatic printing equipment for cells for stably positioning the cell pore plate is needed to be solved.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model aims to provide an automatic device for single-cell printing, which has the effect of centering and positioning cell pore plates with different specifications.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
an automation equipment for single cell prints, includes the organism, be formed with on the organism and print the cavity, print the intracavity and be provided with printing mechanism, print still to be provided with the fixing base in the cavity, the fixing base is used for placing the cell orifice plate, still be provided with stop gear and moving mechanism on the fixing base, moving mechanism is used for controlling stop gear and removes along the positioning seat and fix the cell orifice plate.
As a further improvement of the utility model, the limiting mechanism comprises a horizontal limiting component and a vertical limiting component, wherein the horizontal limiting component is used for limiting the length direction of the cell pore plate along the length direction of the machine body, and the vertical limiting component is used for limiting the width direction of the cell pore plate along the width direction of the machine body.
As a further improvement of the utility model, the horizontal limiting assembly comprises a first limiting plate and a second limiting plate, the moving mechanism comprises a horizontal motor, a first double-head screw rod and a first guide rod, the horizontal motor is arranged on the fixing seat, the horizontal motor is connected with the first double-head screw rod, two ends of the first double-head screw rod are respectively connected with the first limiting plate and the second limiting plate, the fixing seat is provided with a sliding groove for sliding the first limiting plate and the second limiting plate, and the first guide rod and the first double-head screw rod are symmetrically arranged and connected with the first limiting plate and the second limiting plate.
As a further improvement of the utility model, the first limiting plate is higher than the second limiting plate, and the side wall of the first limiting plate, which is higher than the second limiting plate, is provided with a forward micro-control switch for controlling the horizontal motor, and the forward micro-control switch is used for controlling the horizontal motor to rotate forward and controlling the first limiting plate and the second limiting plate to move back to back.
As a further improvement of the utility model, the side wall of the first limiting plate is also provided with a reverse micro-control switch, and the reverse micro-control switch and the forward micro-control switch are arranged along the mirror image of the first limiting plate.
As a further improvement of the utility model, a tongue plate is arranged on one side of the second limiting plate far away from the fixed seat.
As a further improvement of the utility model, the moving mechanism further comprises a vertical motor and a second double-headed screw, the vertical motor is arranged in a fixed seat, the vertical limiting component comprises a guide plate and two connecting plates, the fixed seat is provided with a moving groove for sliding of the guide plate, the moving groove is arranged vertically to the sliding groove, the vertical motor is connected with the second double-headed screw, two ends of the second double-headed screw are respectively connected with the guide plate, and a height difference is formed between the oppositely arranged guide plates;
straight flute has been seted up in the deflector, two the connecting plate sets up in straight flute and symmetry setting and one end stretches out the deflector, the connecting plate is located the one end that the deflector is connected with the bracing piece, the slot has been seted up to connecting plate joint support's one end symmetry position, bracing piece on the connecting rod inserts respectively and establishes to the slot of relative position in, the connecting plate is kept away from the one end that sets up the bracing piece and is provided with the slipknot, the guide way that supplies the slipknot to slide has been seted up respectively along second duplex screw axis direction to one side that first limiting plate and second limiting plate are in opposite directions.
As a further improvement of the utility model, the inner side walls of the first limiting plate, the second limiting plate and the guide plate are respectively provided with a convex rib, and the outer wall of the cell pore plate is provided with a groove for inserting the convex rib.
The utility model has the beneficial effects that: through the stop gear who sets up makes when placing the cell orifice plate, triggers moving mechanism and carries out adaptability to stop gear according to cell orifice plate size to satisfy stop gear and carry out centering location to the cell orifice plate, thereby make when carrying out cell printing, the micro-jet pipe can carry out accurate removal according to the printing route that the system preset, and realize the printing to the cell.
Drawings
FIG. 1 is a schematic perspective view of a structure embodying the present utility model;
FIG. 2 is a schematic diagram showing the structure of a spacing mechanism and a moving mechanism;
FIG. 3 is a schematic cross-sectional view illustrating a vertical stop assembly.
Reference numerals: 1. a body; 2. a fixing seat; 3. a limiting mechanism; 4. a horizontal limit assembly; 41. a first limiting plate; 42. a second limiting plate; 5. a vertical limit assembly; 51. a guide plate; 52. a connecting plate; 53. a slot; 6. a moving mechanism; 61. a horizontal motor; 62. a first double-ended screw; 63. a first guide bar; 64. a vertical motor; 65. and a second double-ended screw.
Detailed Description
The utility model will now be described in further detail with reference to the drawings and examples. Wherein like parts are designated by like reference numerals. It should be noted that the words "front", "back", "left", "right", "upper" and "lower" used in the following description refer to directions in the drawings, and the words "bottom" and "top", "inner" and "outer" refer to directions toward or away from, respectively, the geometric center of a particular component.
Referring to fig. 1 to 3, an embodiment of an automated device for single-cell printing according to the present utility model includes a machine body 1, a printing chamber is formed on the machine body 1, and a printing mechanism is disposed in the printing chamber, and a printing principle of the printing mechanism is not described in detail herein in the prior art. Still be provided with fixing base 2 in the printing chamber, fixing base 2 is used for placing the cell orifice plate, still be provided with stop gear 3 and moving mechanism 6 on the fixing base 2, moving mechanism 6 is used for controlling stop gear 3 and removes along the positioning seat and fix the cell orifice plate, stop gear 3 includes horizontal spacing subassembly 4 and perpendicular spacing subassembly 5, horizontal spacing subassembly 4 is used for spacing cell orifice plate length direction along organism 1 length direction, perpendicular spacing subassembly 5 is used for spacing cell orifice plate width direction along organism 1 width direction to realize fixing in the synchronous centering of level and perpendicular direction to the cell orifice plate, realize the fixed effect of location to cell orifice plate position accuracy stable.
The horizontal limiting assembly 4 comprises a first limiting plate 41 and a second limiting plate 42, the moving mechanism 6 comprises a horizontal motor 61, a first double-head screw rod 62 and a first guide rod 63, the horizontal motor 61 is arranged on the fixed seat 2, the horizontal motor 61 is connected with the first double-head screw rod 62, two ends of the first double-head screw rod 62 are respectively connected with the first limiting plate 41 and the second limiting plate 42, a sliding groove for sliding the first limiting plate 41 and the second limiting plate 42 is formed in the fixed seat 2, and the first guide rod 63 and the first double-head screw rod 62 are symmetrically arranged and are connected with the first limiting plate 41 and the second limiting plate 42. The first limiting plate 41 is higher than the second limiting plate 42, a forward micro-control switch for controlling the horizontal motor 61 is arranged on the side wall of the first limiting plate 41 higher than the second limiting plate 42, forward micro-control light is used for controlling the horizontal motor 61 to rotate forward and controlling the first limiting plate 41 and the second limiting plate 42 to move back to back, a reverse micro-control switch is further arranged on the side wall of the first limiting plate 41, the reverse micro-control switch and the forward micro-control switch are arranged along the mirror image of the first limiting plate 41, a tongue plate is arranged on one side, far away from the fixed seat 2, of the second limiting plate 42, a power-off switch is arranged on the side wall of the second limiting plate 42, and power-off light is used for controlling the horizontal motor 61 to stop moving.
When the size of the cell pore plate is larger than the distance between the first limiting plate 41 and the second limiting plate 42, the first limiting plate 41 is higher than the second limiting plate 42, and then the cell pore plate is placed and touched to a positive micro-control switch positioned on the side wall of the first limiting plate 41, the horizontal motor 61 is controlled to drive the first double-headed screw 62 to rotate so as to adjust the distance between the first limiting plate 41 and the second limiting plate 42 to be increased, so that the cell pore plate is adjusted to meet the requirement of the cell pore plate, and then the cell pore plate is touched to a power-off switch so that the horizontal motor 61 stops rotating, and the cell pore plate is positioned.
When the size of the cell pore plate is smaller than the distance between the first limiting plate 41 and the second limiting plate 42, the cell pore plate is placed along the side wall direction of the first limiting plate 41, at the moment, a reverse micro-control switch is touched when the cell pore plate is placed, the horizontal motor 61 is controlled to drive the first double-headed screw 62 to rotate so as to adjust the distance between the first limiting plate 41 and the second limiting plate 42 to be reduced, so that the cell pore plate is adjusted to meet the requirement of the cell pore plate, and at the moment, the cell pore plate is touched to a power-off switch so that the horizontal motor 61 stops rotating, and the cell pore plate is positioned.
The moving mechanism 6 further comprises a vertical motor 64 and a second double-head screw rod 65, the vertical motor 64 is arranged in the fixed seat 2, the vertical limiting component 5 comprises a guide plate 51 and two connecting plates 52, the fixed seat 2 is provided with a moving groove for sliding the guide plate 51, the moving groove is arranged vertically with the sliding groove, the vertical motor 64 is connected with the second double-head screw rod 65, two ends of the second double-head screw rod 65 are respectively connected with the guide plate 51, a height difference is formed between the oppositely arranged guide plates 51, micro-control switches for controlling the vertical motor 64 to rotate forward to drive the guide plates 51 to move away from each other are arranged on the side wall of the guide plate 51 with a high point, micro-control switches for controlling the vertical motor 64 to rotate reversely to drive the guide plates 51 to move oppositely are also arranged at symmetrical positions along the guide plates 51, and power-off switches for controlling the power-off of the vertical motor 64 are arranged on the inner side walls of the guide plates 51 with a first point;
straight flute has been seted up in the deflector 51, two the connecting plate 52 sets up in straight flute and symmetry setting and one end stretches out the deflector 51, the one end that connecting plate 52 is located deflector 51 is connected with the bracing piece, slot 53 has been seted up to the one end symmetry position of connecting plate 52 joint support pole, the bracing piece on the connecting rod inserts respectively to the slot 53 of relative position in, the one end that the connecting plate 52 kept away from setting up the bracing piece is provided with the slipway, the guide way that supplies the slipway to slide has been seted up respectively along second double-end screw 65 axis direction to one side that first limiting plate 41 and second limiting plate 42 are in opposite directions.
So that when the first limiting plate 41 and the second limiting plate 42 are adjusted to move, the connecting plate 52 is driven to slide along the guide plate 51 for adjustment, and when the vertical motor 64 controls the second double-head screw 65 to move, the guide plate 51 is driven to move for adjustment, so that the guide plate 51 positions and fixes the cell pore plate along the vertical direction, and the mode that the vertical motor 64 regulates and controls the guide plate 51 to move is the same as the mode that the horizontal motor 61 regulates and controls the first limiting plate 41 and the second limiting plate 42 to move.
Working principle and effect:
through the stop gear 3 that sets up makes when placing the cell orifice plate, triggers moving mechanism 6 and carries out the adaptability to stop gear 3 according to cell orifice plate size to satisfy stop gear 3 and carry out centering location to the cell orifice plate, thereby make when carrying out cell printing, the micro-jet pipe can be according to the printing route that the system preset and carry out accurate removal, and realize the printing to the cell.
The above description is only a preferred embodiment of the present utility model, and the protection scope of the present utility model is not limited to the above examples, and all technical solutions belonging to the concept of the present utility model belong to the protection scope of the present utility model. It should be noted that modifications and adaptations to the present utility model may occur to one skilled in the art without departing from the principles of the present utility model and are intended to be within the scope of the present utility model.
Claims (8)
1. An automated device for single-cell printing, comprising a machine body (1), wherein a printing chamber is formed on the machine body (1), and a printing mechanism is arranged in the printing chamber, and the automated device is characterized in that: still be provided with fixing base (2) in the printing chamber, fixing base (2) are used for placing the cell orifice plate, still be provided with stop gear (3) and moving mechanism (6) on fixing base (2), moving mechanism (6) are used for controlling stop gear (3) and move along the positioning seat and fix the cell orifice plate.
2. An automated apparatus for single cell printing according to claim 1, wherein: the limiting mechanism (3) comprises a horizontal limiting assembly (4) and a vertical limiting assembly (5), the horizontal limiting assembly (4) is used for limiting the length direction of the cell pore plate along the length direction of the machine body (1), and the vertical limiting assembly (5) is used for limiting the width direction of the cell pore plate along the width direction of the machine body (1).
3. An automated apparatus for single cell printing according to claim 2, wherein: the horizontal limiting assembly (4) comprises a first limiting plate (41) and a second limiting plate (42), the moving mechanism (6) comprises a horizontal motor (61), a first double-headed screw (62) and a first guide rod (63), the horizontal motor (61) is arranged on the fixed seat (2), the horizontal motor (61) is connected with the first double-headed screw (62), two ends of the first double-headed screw (62) are respectively connected with the first limiting plate (41) and the second limiting plate (42), sliding grooves for sliding the first limiting plate (41) and the second limiting plate (42) are formed in the fixed seat (2), and the first guide rod (63) and the first double-headed screw (62) are symmetrically arranged and connected with the first limiting plate (41) and the second limiting plate (42).
4. An automated apparatus for single cell printing according to claim 3, wherein: the first limiting plate (41) is higher than the second limiting plate (42), a forward micro-control switch for controlling the horizontal motor (61) is arranged on the side wall of the first limiting plate (41) higher than the second limiting plate (42), and forward micro-control light is used for controlling the horizontal motor (61) to rotate forward and controlling the first limiting plate (41) and the second limiting plate (42) to move away from each other.
5. An automated apparatus for single cell printing according to claim 4, wherein: the side wall of the first limiting plate (41) is also provided with a reverse micro-control switch, and the reverse micro-control switch and the forward micro-control switch are arranged along the mirror image of the first limiting plate (41).
6. An automated apparatus for single cell printing according to claim 5, wherein: one side of the second limiting plate (42) far away from the fixed seat (2) is provided with a tongue plate, the side wall of the second limiting plate (42) is provided with a power-off switch, and the power-off switch is used for controlling the horizontal motor (61) to stop moving.
7. An automated apparatus for single cell printing according to claim 6, wherein: the moving mechanism (6) further comprises a vertical motor (64) and a second double-head screw rod (65), the vertical motor (64) is arranged in the fixed seat (2), the vertical limiting assembly (5) comprises a guide plate (51) and two connecting plates (52), a moving groove for the guide plate (51) to slide is formed in the fixed seat (2), the moving groove is vertically arranged with the sliding groove, the vertical motor (64) is connected with the second double-head screw rod (65), two ends of the second double-head screw rod (65) are respectively connected with the guide plate (51), and a height difference is formed between the guide plates (51) which are oppositely arranged;
straight flute has been seted up in deflector (51), two connecting plate (52) set up in the straight flute and symmetry set up and one end stretches out deflector (51), connecting plate (52) are located the one end of deflector (51) and are connected with the bracing piece, slot (53) have been seted up to the one end symmetry position of connecting plate (52) joint support pole, bracing piece on connecting plate (52) inserts respectively in slot (53) to the relative position, connecting plate (52) keep away from the one end that sets up the bracing piece and are provided with the sliphead, the guide way that supplies the sliphead to slide is seted up respectively along second double-end screw (65) axis direction to one side that first limiting plate (41) and second limiting plate (42) are in opposite directions.
8. An automated apparatus for single cell printing according to claim 7, wherein: the cell pore plate is characterized in that ribs are respectively arranged on the inner side walls of the first limiting plate (41), the second limiting plate (42) and the guide plate (51), and grooves for inserting the ribs are formed in the outer wall of the cell pore plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223196215.4U CN219507934U (en) | 2022-11-30 | 2022-11-30 | Automatic equipment for single-cell printing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223196215.4U CN219507934U (en) | 2022-11-30 | 2022-11-30 | Automatic equipment for single-cell printing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219507934U true CN219507934U (en) | 2023-08-11 |
Family
ID=87550493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223196215.4U Active CN219507934U (en) | 2022-11-30 | 2022-11-30 | Automatic equipment for single-cell printing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219507934U (en) |
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2022
- 2022-11-30 CN CN202223196215.4U patent/CN219507934U/en active Active
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