CN219482601U - Multi-layer mixing core microreactor with combination of row holes and inserting sheet meshes - Google Patents

Abstract

The utility model discloses a multi-layer mixing core microreactor with a combination of row holes and insert mesh holes, which comprises an outer sleeve in the shape of a rectangular flat tube and multi-layer combined rectangular insert inserted into an inner cavity of the outer sleeve, wherein the rectangular insert is made of tubular channels which are arranged on the upper surface or/and the lower surface of a rectangular long slat in rows and are provided with holes at two ends, and mesh holes are regularly arranged on the rectangular insert. The utility model relates to a combined mixing core with holes and meshes, which relates to various variable technical specifications, including symmetrical structures and asymmetrical structures, and can also conveniently adjust the combination and size of the holes and the meshes, the shape and size of the holes, different combinations of multi-layer inserting sheets and the like, and can conveniently adjust different requirements in the actual process and production process. The problems that the existing micro-reactor is difficult to clean after scaling, the disassembly and assembly process is time-consuming, the replacement of the mixing unit is inconvenient, and the design flexibility of the mixing core is low are mainly solved.

Description

Multi-layer mixing core microreactor with combination of row holes and inserting sheet meshes

Technical Field

The utility model relates to the technical field of microreactors, in particular to a multi-layer mixing core microreactor with a combination of hole arrangement and inserted sheet meshes.

Background

Microreactors are capable of performing chemical reactions in a length scale of tens to hundreds of millimeters, the most typical configuration being microchannels. In recent years, a micro-reactor with a detachable mixing core becomes the mainstream, and is widely applied to the pharmaceutical and chemical industry with high requirements on equipment cleaning and maintenance in a continuous production process. The design and application of micro-holes are involved in a plurality of micro-reactors, such as CN215917350U, CN216260684U, CN215540778U, CN215842929U disclosed by the company is a detachable cylindrical mixing core with holes. The mixing core is a core component of the microreactor, and can remarkably improve the mixing performance of the microreactor, thereby improving the reaction effect of the microreactor.

However, the above-described mixing core structure is relatively complex and is only suitable for a sleeve type micro-channel reactor design, and cannot be satisfied for a micro-reactor having rectangular flat-tube type micro-channels with a larger heat exchange area than a sleeve type micro-reactor or a tube type reactor. Therefore, there is an urgent need to develop a multi-layer stacked hybrid core microreactor suitable for rectangular flat tube outer sleeves, which has a simple hybrid core structure and easy processing, and has a combination design of various hole structures.

Disclosure of Invention

The present utility model aims to solve at least one of the technical problems in the related art to some extent. Therefore, the utility model aims to provide a multi-layer mixing core microreactor with a combination of hole arrangement and inserting sheet meshes, which solves the problems of complex mixing core structure, inconvenient processing, unsatisfactory liquid mixing effect and the like.

The utility model provides a multi-layer mixing core microreactor combining row holes and inserting sheet meshes, which comprises an outer sleeve (10) in the shape of a rectangular flat tube and multi-layer combined rectangular inserting sheets (1) inserted into the inner cavity of the outer sleeve (10), wherein the rectangular inserting sheets (1) are formed by arranging row-shaped channels with holes at two ends on the upper surface or/and the lower surface of a rectangular long slat in rows and regularly arranging meshes on the rectangular inserting sheets (1); the row of channels flow substantially parallel to the rectangular tab plane.

In some embodiments of the present utility model, the rows of channels on the upper surface and the rows of channels on the lower surface of the rectangular long slat are staggered, and may be straight channels or streamline curved channels, and the sizes of the inlets and the outlets at two ends of the rows of channels may be the same or different; the meshes on the rectangular inserting sheet (1) are arranged at the middle position of the front side of one end of the row of channels or the front sides of the same end of two adjacent row of channels, or the meshes on the rectangular inserting sheet (1) are arranged below the row of channels.

In some embodiments of the present utility model, the rows of channels on the upper surface and the rows of channels on the lower surface of the rectangular long strip plate are provided with holes except for two ends, and the channel wall outside the plane of the rectangular inserting sheet may also be provided with a strip-shaped opening or a notch suitable for the streamline of the channel.

In some embodiments of the present utility model, the rows of channels may have holes at only one end, the holes of the rows of channels on the upper and lower surfaces face the same direction, and the mesh on the rectangular insert (1) is disposed below the rows of channels and the length of the mesh is greater than the length of the rows of channels.

In some embodiments of the present utility model, the row of channels on the rectangular insert (1) is one or a combination of semi-cylindrical row of channels, quarter-ball row of channels, quarter-football row of channels, half-horn row of channels; when the mesh is arranged below the row of channels, the mesh is one of semicircular holes, round holes, elliptical holes, square holes, rectangular holes, triangular holes and pentagram holes. The mesh shape can also be one or more of oblique bar shape, fishbone shape, herringbone shape, pill shape, octagon hole, splayed hole, cross hole, plum blossom hole, diamond hole, fish eye hole, special-shaped hole, combined hole, shutter hole, etc.

In some embodiments of the present utility model, the number of rectangular insertion pieces inserted into each outer sleeve (10) is not less than 3, the sum of the total thicknesses of the rectangular insertion pieces (1) after combination is 1-10% smaller than the height of the inner cavity of the outer sleeve (10), and the ratio of the height to the width of the inner cavity of the outer sleeve (10) is 1:2-20.

In some embodiments of the utility model, the rectangular insert sheet (1) has a thickness of 0.1-5mm, a width of 5-50mm and a length of 50-1500mm.

In some embodiments of the present utility model, the rectangular insert (1) is made of one or more of galvanized steel sheet, cold rolled sheet, copper sheet, nickel sheet, stainless steel sheet, aluminum alloy sheet, hastelloy, polymer material, ceramic, graphene and silicon carbide.

In some embodiments of the utility model, a plurality of the outer sleeves (10) are connected in parallel to form a unit, and the units formed by the outer sleeves (10) are connected in series to form an integrated microreactor; the two ends of the outer sleeve (10) are plugged by seal heads, and sealing gaskets are arranged at contact positions between the seal heads and the outer sleeve in a cushioning manner and are fixed on the outer sleeve (10) by screws.

In other embodiments of the present utility model, the surface of the multi-layer mixing core aperture and the opening of the aperture of the combination of row holes and insert mesh have a roughness Ra of no more than 0.8 μm.

In some embodiments of the utility model, the specific steps are as follows:

s1: stacking a plurality of layers of rectangular inserting pieces (1), wherein if the rectangular inserting pieces (1) are provided with row channels on one side, the row channels on the rectangular inserting pieces (1) which are adjacent up and down correspond up and down, and if the rectangular inserting pieces (1) are provided with row channels on both sides, the bulges on the upper surface of the rectangular inserting pieces (1) on the lower layer correspond to the non-bulge positions on the lower surface of the rectangular inserting pieces (1) on the upper layer;

s2: sealing is carried out at two ends of the outer sleeve (10) by using the sealing heads, sealing gaskets are arranged between the sealing heads and the outer sleeve (10), and the sealing heads are fixed on the outer sleeve (10) by using screws;

s3: and a plurality of outer sleeves (10) are connected in parallel to form a unit, and the units formed by the outer sleeves (10) are connected in series to form the integrated microreactor.

The advantages in the present utility model are listed below, but are not limited thereto: 1) The rectangular flat channel of the inner cavity of the outer sleeve has larger specific surface area relative to the tubular channel, and the heat exchange performance of the process in the integral microreactor is obviously improved; 2) The mixed core with the combination of the single-layer row holes and the inserting sheet meshes can promote the material mixing of the single layer through the flexible combination of various hole structures and also realize the turbulent flow of complex channels between layers, thereby improving the reaction mixing effect; 3) The detachable rectangular staggered hole mixing core structure is simple in design and low in processing cost, and is convenient to assemble, disassemble and clean and maintain.

Drawings

The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model. In the drawings:

FIG. 1 is a schematic diagram of a multi-layer hybrid core microreactor with a combination of row holes and insert mesh (semi-cylindrical row channels) according to the present utility model.

Fig. 2 is a schematic structural view of a rectangular insert sheet of a semi-cylindrical row channel according to the present utility model.

Fig. 3 is a schematic cross-sectional side view of a rectangular tab for a semi-cylindrical row of channels according to the present utility model.

Fig. 4 is a schematic view of the structure of a rectangular insert sheet of a quarter sphere single-sided row of channels (mesh below row of channels) according to the present utility model.

Fig. 5 is a schematic view of the structure of a rectangular insert for a quarter sphere double sided row of channels (mesh below row of channels) according to the present utility model.

Fig. 6 is a schematic side cross-sectional view of a rectangular insert for a quarter sphere double sided row of channels (mesh below row of channels) in accordance with the present utility model.

Fig. 7 is a schematic structural view of rectangular inserts for semi-cylindrical two-sided row channels (with openings at the ends of the row channels) according to the present utility model.

Fig. 8 is a top view of a semi-cylindrical two-sided row of channel rectangular tabs (with openings at the ends of the row of channels) according to the present utility model.

Fig. 9 is a top view of a rectangular tab for a half-cylindrical two-sided row of channels (with openings at intermediate locations between the ends of adjacent two rows of channels) in accordance with the present utility model.

Fig. 10 is a schematic structural view of a single-sided row channel half-horn rectangular insert sheet according to the present utility model.

Fig. 11 is a schematic structural view of a rectangular insert sheet with a plurality of strip-shaped meshes according to the present utility model.

In the figure: 1. rectangular inserting sheets; 2. semi-cylindrical rows of channels; 3. strip-shaped mesh openings; 4. one quarter of the balls form a row channel (upper surface); 40. the balls form mesh holes matched with the row channels; 41. one quarter of the balls form a row channel (lower surface); 5. semi-cylindrical rows of channels (mesh at end, upper surface); 51. semi-cylindrical rows of channels (mesh at end, lower surface); 6. semi-cylindrical rows of channels (end semi-circular mesh, upper surface); 60. semicircular mesh openings; 61. semi-cylindrical rows of channels (end semi-circular mesh, lower surface); 7. the half horns form a row channel; 71. the half-horns form a mesh under the row channels.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments.

The utility model provides a multi-layer mixing core microreactor with a row of holes and insert mesh combination, which comprises an outer sleeve 10 in the shape of a rectangular flat tube and a multi-layer combined rectangular insert 1 inserted into an inner cavity of the outer sleeve 10, wherein the rectangular insert 1 is made by arranging row-shaped channels with holes at two ends on the upper surface or/and the lower surface of a rectangular long slat in rows and regularly arranging meshes on the rectangular insert 1; the row of channels flow substantially parallel to the rectangular tab plane.

The upper surface of the rectangular long slat is provided with staggered rows of channels and the lower surface of the rectangular long slat, the rectangular long slat can be straight channels or streamline curved channels, and the sizes of inlets and outlets at two ends of the rows of channels can be the same or different; the meshes on the rectangular inserting sheet 1 are arranged at the middle position of the front side of one end of the row of channels or the front sides of the same end of two adjacent row of channels, or the meshes on the rectangular inserting sheet 1 are arranged below the row of channels.

The rows of channels can be provided with holes at one end only, the holes of the rows of channels arranged on the upper surface and the lower surface face the same direction, and the meshes on the rectangular inserting sheet 1 are arranged below the rows of channels and the length of the meshes is larger than that of the rows of channels.

If the mesh is arranged below the row channels, the holes on the row channels are communicated with the mesh, so that the holes on the row channels are communicated with the rectangular inserting pieces 1, the reacted liquid directly flows into the mesh from the holes, so that the liquid flows in series on the upper surface and the lower surface, and when the mesh is arranged at the end part of the row channels, the liquid flows between the rectangular inserting pieces 1 in a multi-layer combined mode, the liquid flows in series up and down from the mesh at the end part, and the row channels play a supporting and flow limiting role.

The rows of channels are distributed in an array or staggered way (the middle axes of two adjacent rows of channels in the upper transverse row are in the same straight line with the rows of channels in the lower row), when the mesh holes on the rectangular inserting sheet 1 are arranged below the rows of channels, the length of the mesh holes is larger than that of the rows of channels, the flow resistance exists when the liquid flows to the positions of the rows of channels, the mesh holes at the end parts of the flow resistance positions directly flow down, namely, the fluidity of the liquid is greatly improved by one section of mesh holes at more positions than the rows of channels, and if the liquid flows at the other positions, the flow resistance only flows in the interlayer.

When the rectangular inserting sheet 1 is provided with meshes below the row of channels, the meshes can be formed by 1-5 strip-shaped meshes 3 in parallel. The strip-shaped meshes 3 can split liquid to achieve a better mixed flow effect, but the strip-shaped meshes are not too much, and the mesh gaps are small, so that the liquid circulation is not facilitated.

The number of the combined rectangular inserting sheets inserted into each outer sleeve 10 is not less than 3, the sum of the total thicknesses of the rectangular inserting sheets 1 after combination is 1-10% smaller than the height of the inner cavity of the outer sleeve 10, and the ratio of the height to the width of the inner cavity of the outer sleeve 10 is 1:2-20. The rectangular inserting sheet 1 has the thickness of 0.1-5mm, the width of 5-50mm and the length of 50-1500mm. The effect of forming turbulent flow on a plurality of fluid streams by more than three combined type inserting sheets is better, preferably 3-5, and the height of the inner cavity 2 can be increased too much, so that the micro-reaction effect of the flat channel can not be achieved.

The rectangular inserting sheet 1 is made of one or a combination of galvanized steel plate, cold-hot rolled plate, copper plate, nickel plate, stainless steel plate, aluminum alloy plate, hastelloy, polymer material, ceramic, graphene or silicon carbide.

The row channels on the rectangular inserting sheet 1 are one or a combination of semi-cylindrical row channels, quarter-ball forming row channels, quarter-football forming row channels and half-horn forming row channels;

the row channels on the upper surface and the row channels on the lower surface of the rectangular long slat are provided with holes except two ends, and the channel wall outside the plane of the rectangular inserting sheet can be provided with strip-shaped holes or cuts suitable for channel streamline;

when the mesh is arranged at one end of the row of channels, the mesh is one of semicircular holes, round holes, elliptical holes, square holes, rectangular holes, triangular holes and pentagram holes.

The mesh shape can also be one or more of oblique bar shape, fishbone shape, herringbone shape, pill shape, octagon hole, splayed hole, cross hole, plum blossom hole, diamond hole, fish eye hole, special-shaped hole, combined hole, shutter hole, etc.

The outer sleeves 10 are connected in parallel to form a unit, and the units formed by the outer sleeves 10 are connected in series to form an integrated microreactor.

The flow rate and the flow rate of the liquid in each outer sleeve 1 are limited in a certain range, a plurality of outer sleeves 1 are connected in parallel to form a unit under the condition of ensuring high flow rate and flow rate, and the units formed by the outer sleeves 1 are connected in series to form an integrated microreactor so as to improve the reaction speed.

The surface roughness Ra of the rectangular inserting sheet is not more than 0.8 mu m. Prevent that extra friction from producing the mar when porous inserted sheet dismouting and between the outer tube, also avoid having solid foreign matter to hang at reactor wall or porous structure dead angle increase the washing degree of difficulty, reduce unnecessary pressure drop simultaneously and produce.

The method for installing the multi-layer mixed core microreactor with the combination of the combined row holes and the inserted sheet meshes comprises the following specific steps:

s1: combining a plurality of layers of rectangular inserting sheets 1, wherein if the rectangular inserting sheets 1 are provided with row channels on one side, the row channels on the rectangular inserting sheets 1 which are adjacent up and down correspond up and down, and if the rectangular inserting sheets 1 are provided with row channels on both sides, the row channels on the upper surface of the rectangular inserting sheets 1 on the lower layer correspond to the non-row channels on the lower surface of the rectangular inserting sheets 1 on the upper layer;

s2: sealing is carried out at two ends of the outer sleeve 10 by using the sealing heads, sealing gaskets are arranged between the sealing heads and the outer sleeve 10, and the sealing heads are fixed on the outer sleeve 10 by using screws;

s3: the outer sleeves 10 are connected in parallel to form a unit, the units formed by the outer sleeves 10 are connected in series to form an integrated microreactor, the units formed by the outer sleeves are connected in parallel to form a unit, and the units formed by the outer sleeves are connected in series to form the integrated microreactor.

Multilayer hybrid core of row hole and insert mesh combination example 2: and (5) disassembling.

In the actual use process of the rectangular porous inserting piece, if scaling or blockage occurs in the equipment, the equipment needs to be cleaned and maintained, screws on the sealing heads at the two ends of the inlet and the outlet can be unscrewed, after the sealing heads are disassembled, one thin rod is used at one end of the inlet and the outlet to push the rectangular inserting piece out of a small section, and then the inserting piece is directly pulled out from the other end, so that the disassembly procedure can be completed.

Cleaning and maintaining the multi-layer mixing core with the combination of row holes and inserting sheet meshes.

The rectangular inserting sheet is cleaned and maintained, and is usually placed in a container filled with cleaning agent for soaking for a certain time, an ultrasonic cleaner can be used in an auxiliary mode, and then a fine brush is used for brushing, so that the cleaning procedure can be completed.

Reassembly of a multi-layer hybrid core (including replacement of hybrid core elements) with a combination of row holes and tab meshes.

After cleaning and maintaining the multi-layer mixed core combined by the row holes and the inserting sheet meshes, if the cores are found to be seriously blocked (additional maintenance treatment is needed outside ultrasonic cleaning) and need to be replaced, or the combined silk screen mixed core with different specifications is needed to be replaced according to the actual situation, the multi-layer mixed core can be reassembled. The multi-layer mixing core is selected according to the situation, for example, the rectangular multi-hole combined mixing core relates to various variable technical specifications, including symmetrical structures and asymmetrical structures, and can also conveniently adjust the combination and the size of the upper surface and the lower surface of the row of channels, the shape and the size of the mesh openings on the inserting sheets, the strip openings or the cuts on the walls of the row of channels according to the shapes of the channels, and the different combinations of the multi-layer rectangular multi-hole combined inserting sheets, and the like, thereby conveniently adjusting the different requirements in the actual process and the production process

The microchannel reactor formed by combining the multi-layer mixing cores with the row holes and the inserting sheet meshes can be conveniently used for a medical intermediate synthesis process which is easy to scale and block. Compared with the conventional all-disassembled Bayer microreactor Meander microreactor, the method has the advantages that from the fact that blockage or scaling is likely to occur (such as the pressure drop of a system is fast), disassembly, cleaning and maintenance are started, the mixing core or the unit is likely to be replaced to be reassembled, the time for the maintenance operation of the microreactor is shortened by at least 30% or even 60%, the maintenance efficiency in the process of process optimization or production is greatly improved, and the technical requirements on operators are low.

The foregoing is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical scheme of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.

Claims (8)

1. A multi-layer hybrid core microreactor combining hole arrangement and insert mesh, which is characterized in that: the rectangular multi-hole plugging device comprises an outer sleeve (10) in the shape of a rectangular flat tube and a plurality of layers of combined rectangular multi-hole plugging sheets (1) plugged into the inner cavity of the outer sleeve (10), wherein the rectangular multi-hole plugging sheets (1) are formed by arranging row-shaped channels with holes at two ends on the upper surface or/and the lower surface of a rectangular long slat in rows and regularly arranging meshes on the rectangular multi-hole plugging sheets (1); the flow direction of the calandria channels is basically parallel to the plane of the rectangular porous inserting sheet.

2. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: the upper surface row channels and the lower surface row channels of the rectangular long strip plate are distributed in a staggered manner, and are straight channels or streamline curved channels, and the sizes of inlets and outlets at two ends of the row channels are the same or different; the meshes on the rectangular porous inserting sheet (1) are arranged at the middle position of the front side of one end of the row of channels or the front sides of the same ends of two adjacent row of channels, or the meshes on the rectangular porous inserting sheet (1) are arranged below the row of channels.

3. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: holes are formed in the two ends of the row-pipe-shaped channels on the upper surface and the row-pipe-shaped channels on the lower surface of the rectangular long slat, and strip-shaped openings or cuts suitable for channel streamline are formed in the channel wall outside the plane of the rectangular porous inserting sheet.

4. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: holes are formed in one end of each row of tubular channels, the holes of the row of channels arranged on the upper surface and the lower surface face the same direction, and the mesh holes on the rectangular porous inserting sheet (1) are arranged below the row of channels, and the length of the mesh holes is larger than that of the row of channels.

5. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: the row channels on the rectangular porous inserting sheet (1) are one or a combination of semi-cylindrical row channels, quarter-ball forming row channels, quarter-football forming row channels and half-horn forming row channels; when the mesh is arranged below the row of channels, the mesh is one of semicircular holes, round holes, elliptical holes, square holes, rectangular holes, triangular holes and pentagram holes, and can also be one or more of oblique bars, fishbone shapes, herringbone shapes, pill shapes, octagram holes, splayed holes, cross holes, plum blossom holes, diamond holes, fish eye holes, special-shaped holes, combined holes and shutter holes.

6. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: the number of the rectangular porous inserting sheets plugged into each outer sleeve (10) is not less than 3, the sum of the total thickness of the rectangular porous inserting sheets (1) after combination is 1-10% smaller than the height of the inner cavity of the outer sleeve (10), and the ratio of the height to the width of the inner cavity of the outer sleeve (10) is 1:2-20.

7. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: the rectangular porous inserting sheet (1) has the thickness of 0.1-5mm, the width of 5-50mm and the length of 50-1500mm.

8. A multi-layer hybrid core microreactor incorporating a row of holes and insert mesh as claimed in claim 1 wherein: a plurality of outer sleeves (10) are connected in parallel to form a unit, and the units formed by the outer sleeves (10) are connected in series to form an integrated microreactor; the two ends of the outer sleeve (10) are plugged by seal heads, and sealing gaskets are arranged at contact positions between the seal heads and the outer sleeve in a cushioning manner and are fixed on the outer sleeve (10) by screws.