CN219441725U

CN219441725U - Suction head grabbing assembly and pipetting mechanism with suction head grabbing assembly

Info

Publication number: CN219441725U
Application number: CN202223499613.3U
Authority: CN
Inventors: 雷宇; 韩琳; 吴文昊
Original assignee: MGI Tech Co Ltd
Current assignee: MGI Tech Co Ltd
Priority date: 2022-12-23
Filing date: 2022-12-23
Publication date: 2023-08-01
Anticipated expiration: 2032-12-23

Abstract

The utility model provides a suction head grabbing assembly and a pipetting mechanism with the same, wherein the suction head grabbing assembly is used for grabbing suction heads and comprises: the liquid-transferring gun head is connected with the suction head in a pluggable manner; a cavity is arranged in the connecting pipe; an opening part which is arranged on the outer side wall of the pipetting gun head and is communicated with the cavity; the flexible part is arranged at the opening part and is provided with an initial position and an expansion position, and when the flexible part is in the expansion position, the flexible part is in abutting fit with the suction head; the through hole is arranged on the outer side wall of the pipetting gun head and is communicated with the cavity; when the medium is injected into the cavity through the through hole, the flexible part moves from the initial position to the expansion position. The technical scheme of the application effectively solves the problem that the pipette tip in the related technology is easy to generate adverse resistance when grabbing the suction head.

Description

Suction head grabbing assembly and pipetting mechanism with suction head grabbing assembly

Technical Field

The utility model relates to the technical field of pipettors, in particular to a suction head grabbing assembly and a pipetting mechanism with the suction head grabbing assembly.

Background

A pipette is a metering tool that removes liquid from an original container into another container. In experiments of medical research, in particular in experiments of studying cell changes, a protective structure is formed between a pipette and a sample by the pipette being matched with a suction head. Therefore, the safety of sucking the sample and separating the sample is guaranteed, and the human medical treatment is better served.

In the related art, the adapter of the pipette is provided with the protruding sealing ring, and in the process of grabbing the suction head, the sealing ring is extruded and deformed by the inner wall of the suction head to generate certain friction force so as to achieve the purpose of grabbing the suction head, and adverse resistance can be generated in the grabbing process, so that the step loss of a motor is easily caused, and a relatively large height error is caused, so that the subsequent automatic pipetting work is influenced.

Disclosure of Invention

The utility model mainly aims to provide a suction head grabbing component and a pipetting mechanism with the suction head grabbing component, so as to solve the problem that a pipetting gun head in the related art is easy to generate adverse resistance when grabbing a suction head.

In order to achieve the above object, according to one aspect of the present utility model, there is provided a suction head gripping assembly for gripping a suction head, the suction head gripping assembly comprising: the liquid-transferring gun head is connected with the suction head in a pluggable manner; a cavity is arranged in the pipette tip; an opening part which is arranged on the outer side wall of the pipetting gun head and is communicated with the cavity; the flexible part is arranged at the opening part and is provided with an initial position and an expansion position, and when the flexible part is in the expansion position, the flexible part is in abutting fit with the suction head; the through hole is arranged on the outer side wall of the pipetting gun head and is communicated with the cavity; when the medium is injected into the cavity through the through hole, the flexible part moves from the initial position to the expansion position.

Further, a slope part is arranged on the inner wall of the opening part, and the slope part is obliquely arranged from the inner wall of the pipette tip to the edge of the opening part.

Further, the opening is an annular notch arranged around the pipe wall of the pipette tip, and the flexible part is arranged in the cavity and is in sealing connection with the opening.

Further, the flexible portion is fixed by adhesion or clamping or fastening.

Further, the flexible portion is made of rubber or silica gel.

Further, the through hole and the opening portion are provided at a spacing.

Further, the suction head grabbing assembly further comprises an air inlet and outlet assembly, and the air inlet and outlet assembly is communicated with the through hole.

Further, the suction head grabbing assembly further comprises a pressure detection piece, wherein the pressure detection piece is arranged in the cavity and used for detecting the pressure in the cavity.

Further, when the suction head grabbing component grabs the suction head, the change of the pressure value detected by the pressure monitoring piece is the same in the preset time, and when the suction head grabbing component does not grab the suction head, the change of the pressure value detected by the pressure monitoring piece is different in the preset time.

According to another aspect of the present utility model, there is provided a pipetting mechanism comprising a tip grabbing assembly as described above.

By applying the technical scheme of the utility model, the suction head grabbing component is used for grabbing the suction head. In particular, the tip grasping assembly includes a pipette tip removably connected to the tip. The cavity sets up in the pipe wall of liquid-transfering gun head, and the opening setting is on the lateral wall of liquid-transfering gun head and with the cavity intercommunication, and flexible portion sets up in opening department, and flexible portion has initial position and expansion position. The through hole is arranged on the outer side wall of the pipetting gun head and communicated with the cavity, and the through hole and the opening are arranged at intervals. Through the arrangement, the medium is injected into the cavity through the through hole, and the flexible part is extruded and then moves from the initial position to the expansion position. Specifically, when the flexible part is in the initial position, the pipette tip is inserted into the suction head, and then a medium is injected into the cavity through the through hole, so that the flexible part is in the expansion position, and the flexible part is in extrusion fit with the inner wall of the suction head, so that the pipette tip and the suction head are connected. Such connection is softer, can not produce the rigid contact, and then can avoid the suction head to be damaged, simultaneously because flexible portion and suction head extrusion, and then can guarantee sealing performance. Therefore, the technical scheme effectively solves the problem that the pipette tip in the related technology is easy to generate adverse resistance when grabbing the suction head.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the utility model. In the drawings:

FIG. 1 shows a schematic structural view of a pipette tip of an embodiment of a tip grasping assembly according to the utility model;

FIG. 2 shows a schematic view of the flexible portion of the pipette tip of FIG. 1 in an expanded position;

FIG. 3 shows a schematic view of the pipette tip of FIG. 1 inserted into a pipette tip;

figure 4 shows a schematic view of the structure of the flexible portion of figure 3 in contact with the suction head;

fig. 5 shows a schematic view of the separation of the pipette tip and tip of fig. 1.

Wherein the above figures include the following reference numerals:

1. a suction head; 10. pipetting gun heads; 11. an outer tube; 111. a first guiding cone section; 112. a second guiding cone section; 12. an inner tube; 20. a cavity; 30. an opening portion; 40. a flexible portion; 50. and a through hole.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. The following description of at least one exemplary embodiment is merely exemplary in nature and is in no way intended to limit the utility model, its application, or uses. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments in accordance with the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.

The relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present utility model unless it is specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective parts shown in the drawings are not drawn in actual scale for convenience of description. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail, but should be considered part of the specification where appropriate. In all examples shown and discussed herein, any specific values should be construed as merely illustrative, and not a limitation. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further discussion thereof is necessary in subsequent figures.

As shown in fig. 1 to 4, in the present embodiment, a tip grasping assembly is used for grasping a tip 1, the tip grasping assembly including: pipette tip 10, cavity 20, opening 30, flexible portion 40, and through hole 50. The pipette tip 10 is connected to the pipette tip 1 so as to be pluggable. A cavity 20 is provided in the pipette tip 10. The opening 30 is provided on the outer wall of the pipette tip 10 and communicates with the chamber 20. The flexible portion 40 is arranged at the opening 30, the flexible portion 40 having an initial position and an expanded position, the flexible portion 40 and the cleaner head 1 being in abutting engagement when the flexible portion 40 is in the expanded position. The through hole 50 is provided on the outer side wall of the pipette tip 10 and communicates with the cavity 20, and the through hole 50 and the opening 30 are provided at a distance. When the medium is injected into the cavity 20 through the through hole 50, the flexible portion 40 moves from the initial position to the expanded position.

By applying the technical scheme of the embodiment, the suction head grabbing component is used for grabbing the suction head 1. Specifically, the tip grasping assembly includes a pipette tip 10 that is removably connected to the tip 1. The pipette tip 10 is provided with a cavity 20 therein, an opening 30 is provided on an outer side wall of the pipette tip 10 and communicates with the cavity 20, a flexible portion 40 is provided at the opening 30, and the flexible portion 40 has an initial position and an expanded position. The through hole 50 is provided on the outer wall of the pipette tip 10 and communicates with the cavity 20, and the through hole 50 is provided at a distance from the opening 30. With the above arrangement, the medium is injected into the cavity 20 through the through hole 50, and the flexible portion 40 is pressed and moved from the initial position to the expanded position. Specifically, when the flexible portion 40 is at the initial position, the pipette tip 10 is inserted into the pipette tip 1, and then the medium is injected into the cavity 20 through the through hole 50, so that the flexible portion 40 is at the expanded position, and the flexible portion 40 is in press fit with the inner wall of the pipette tip 1, so that the pipette tip 10 and the pipette tip 1 are connected. Such a connection is softer and does not cause a hard contact, and thus the suction head 1 can be prevented from being damaged, and at the same time, the sealing performance can be ensured due to the extrusion of the flexible portion 40 and the suction head 1. Therefore, the technical scheme of the embodiment effectively solves the problem that the pipette tip in the related technology is easy to generate adverse resistance when grabbing the suction head. Moreover, the motor step loss can be prevented, the larger height difference is avoided, and the subsequent automatic pipetting is influenced.

Specifically, in the present embodiment, a pipetting channel is provided inside the pipette tip 10, and the cavity 20 is located outside the pipetting channel, which enables automated pipetting.

Meanwhile, the pipette grabbing component grabs a plurality of pipette tips 1 usually once when grabbing, if hard connection in the prior art is adopted, axial resistance is larger, and connection is difficult to achieve, after the technical scheme of the embodiment is adopted, when the flexible portion 40 is located at the initial position, the flexible portion is inserted into the pipette tips 1, so that the pipette tips are easy to insert, after the flexible portion is inserted into the cavity 20, the flexible portion 40 is further enabled to be in contact with the inner wall of the pipette tips 1, connection is achieved, and the problem that axial resistance is too large can be effectively avoided.

As shown in fig. 1 to 4, in the present embodiment, the pipette tip 10 includes an outer tube 11 and an inner tube 12 provided in the outer tube 11, both ends of the outer tube 11 and both ends of the inner tube 12 are provided in a closed manner, a cavity 20 is provided between the outer tube 11 and the inner tube 12, and an opening portion 30 and a through hole 50 are provided on the outer side wall of the outer tube 11. The outer tube 11 and the inner tube 12 are nested. Both ends of the inner tube 12 and the outer tube 11 are blocked so that a cavity 20 is formed between the inner tube 12 and the outer tube 11. The arrangement of the cavity 20 is simple, and the space of the cavity 20 is large, so that the expansion of the flexible portion 40 is easier.

As shown in fig. 1 and 2, in the present embodiment, the thickness of the wall of the inner tube 12 is greater than that of the outer tube 11. The above arrangement can make the structural strength of the inner tube 12 better.

As shown in fig. 1 and 2, in the present embodiment, a slope portion is provided on the inner wall of the opening portion 30, and the slope portion is provided obliquely from the inner wall of the pipette tip 10 to the edge of the opening portion 30. The provision of the ramp portion can act as a guide for the flexible portion 40, i.e., when the flexible portion 40 expands, the portion of the flexible portion 40 that protrudes outward can engage the ramp portion.

Specifically, in the present embodiment, the slope portion includes a first guide cone section 111 and a second guide cone section 112. The inner side wall of the outer tube 11 is provided with a first guide cone section 111 at a position corresponding to the upper side of the opening 30, the inner side wall of the outer tube 11 is provided with a second guide cone section 112 at a position corresponding to the lower side of the opening 30, and the diameter of the first guide cone section 111 gradually decreases and the diameter of the second guide cone section 112 gradually increases from the upper side to the lower side of the pipette tip 10. The above arrangement of the first and second guiding tapered surface sections 111 and 112 can play a guiding role for the flexible portion 40, that is, when the flexible portion 40 is expanded, the portion of the flexible portion 40 protruding outward can be attached to the first and second guiding tapered surface sections 111 and 112.

As shown in fig. 1 to 5, in the present embodiment, the opening 30 is an annular notch provided around the tube wall of the pipette tip 10, and the flexible portion 40 is provided inside the cavity 20 and is connected with the opening 30 in a sealing manner. The above-mentioned arrangement of the annular gap can make the stability of connection better, and can guarantee the gas tightness of the suction head 1. Specifically, an opening is provided on the outer tube 11.

As shown in fig. 1 to 5, in the present embodiment, the flexible portion 40 is fixed by adhesion or clamping or fastening. Specifically, in the present embodiment, the flexible portion 40 is fixed by means of adhesion, so that the position of the flexible portion 40 can be stabilized, and the fixing means is simple.

As shown in fig. 1 to 5, in the present embodiment, the material of the flexible portion 40 includes rubber or silicone. Specifically, in the present embodiment, the flexible portion 40 is made of rubber.

As shown in fig. 1 to 5, in the present embodiment, the through holes 50 and the opening portions 30 are provided at intervals. This arrangement can avoid interference.

As shown in fig. 1 to 5, in the present embodiment, the opening 30 is located at the lower end of the pipette tip 10, and the through hole 50 is located at the upper end of the pipette tip 10. The above arrangement can better achieve a plug fit and can facilitate filling of the cavity 20 with media.

As shown in fig. 1 to 5, in the present embodiment, the suction head gripping assembly further includes an air intake and exhaust assembly, which communicates with the through hole 50. The arrangement of the air inlet and outlet assembly can effectively realize filling medium or sucking medium out of the cavity 20.

Specifically, in the present embodiment, the medium filled in the cavity 20 is gas, and may be liquid.

As shown in fig. 1 to 5, in the present embodiment, the suction head grabbing assembly further includes a pressure detecting member disposed inside the cavity 20 for detecting the pressure inside the cavity 20. The pressure detection member can effectively detect the pressure in the cavity 20, and further prevent the pressure in the cavity 20 from being too high.

Specifically, as shown in fig. 1 to 5, the tip grabbing assembly of the present embodiment can adapt to tips 1 of different sizes, that is, adjust the pressure in the cavity 20 by changing the amount of injected medium in the cavity 20 to achieve connection with the tips 1 of different sizes, and can determine whether connection between the tips 1 and the pipette tips 10 is stable or not according to the pressure value of the pressure detecting member.

When the suction head grabbing component grabs the suction head 1, the change of the pressure value detected by the pressure monitoring piece is the same in the preset time, and when the suction head grabbing component does not grab the suction head 1, the change of the pressure value detected by the pressure monitoring piece is different in the preset time. The above arrangement makes it possible to identify whether the cleaner head 1 is gripped.

When the suction head 1 is grabbed, there are two possibilities, namely, the suction head 1 is grabbed, at this time, the flexible part 40 is abutted by the suction head 1, medium is continuously injected into the cavity 20, the abutment of the flexible part 40 and the suction head 1 is tighter, the suction head 1 is ensured not to be separated from the suction head grabbing component, in the process, the pressure change of the cavity 20 is uniformly changed, because the volume in the cavity 20 is not substantially changed (the speed of injecting the medium into the cavity 20 is unchanged), the curve of the pressure increase is close to a straight line, and the slope of the curve is close to 1; secondly, the flexible portion 40 is not gripped, and the medium is continuously injected into the cavity 20 because the flexible portion 40 is not abutted by the suction head 1, and the flexible portion 40 is continuously expanded.

The above-described changes in the pressure values are substantially the same, and the change values are not absolutely the same, but the change values change within a small range, but the entire pressure is smoothly increased.

According to another aspect of the present application, there is provided a pipetting mechanism, which includes a pipette tip grabbing assembly, the pipette tip grabbing assembly being the pipette tip grabbing assembly described above. The pipette tip grabbing assembly can effectively achieve connection with the pipette tip 1, and the pipette tip is not easy to damage, so that the pipette tip grabbing assembly has the advantages.

In the description of the present utility model, it should be understood that the azimuth or positional relationships indicated by the azimuth terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal", and "top, bottom", etc., are generally based on the azimuth or positional relationships shown in the drawings, merely to facilitate description of the present utility model and simplify the description, and these azimuth terms do not indicate and imply that the apparatus or elements referred to must have a specific azimuth or be constructed and operated in a specific azimuth, and thus should not be construed as limiting the scope of protection of the present utility model; the orientation word "inner and outer" refers to inner and outer relative to the contour of the respective component itself.

Spatially relative terms, such as "above … …," "above … …," "upper surface at … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial location relative to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the exemplary term "above … …" may include both orientations of "above … …" and "below … …". The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

In addition, the terms "first", "second", etc. are used to define the components, and are only for convenience of distinguishing the corresponding components, and the terms have no special meaning unless otherwise stated, and therefore should not be construed as limiting the scope of the present utility model.

The above description is only of the preferred embodiments of the present utility model and is not intended to limit the present utility model, but various modifications and variations can be made to the present utility model by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.

Claims

1. A suction head gripping assembly for gripping a suction head (1), characterized in that the suction head gripping assembly comprises:

a pipette tip (10), wherein the pipette tip (10) is connected with the suction head (1) in a pluggable manner;

a cavity (20) is arranged in the pipetting gun head (10);

an opening (30) which is provided on the outer side wall of the pipette tip (10) and communicates with the cavity (20);

a flexible portion (40) provided at the opening portion (30), the flexible portion (40) having an initial position and an expanded position, the flexible portion (40) and the suction head (1) being in abutting engagement when the flexible portion (40) is in the expanded position;

a through hole (50) which is arranged on the outer side wall of the pipetting gun head (10) and is communicated with the cavity (20);

wherein when the medium is injected into the cavity (20) through the through hole (50), the flexible part (40) moves from an initial position to an expansion position.

2. The pipette tip grabbing assembly according to claim 1, wherein a slope portion is arranged on the inner wall of the opening portion (30), and the slope portion is obliquely arranged from the inner wall of the pipette tip (10) to the edge of the opening portion (30).

3. The pipette tip grabbing assembly according to claim 1, wherein the opening (30) is an annular gap arranged around the tube wall of the pipette tip (10), and the flexible portion (40) is arranged inside the cavity (20) and is in sealing connection with the opening (30).

4. A suction head gripping assembly according to claim 1, characterized in that the flexible portion (40) is secured by gluing or clamping or fastening.

5. A suction head gripping assembly according to claim 1, characterized in that the flexible portion (40) is of rubber.

6. Suction head gripping assembly according to any of claims 1-5, characterized in that the through-hole (50) and the opening (30) are arranged at a distance.

7. The tip grabbing assembly of any one of claims 1 to 5, further comprising an air intake and exhaust assembly in communication with the through bore (50).

8. The tip grabbing assembly of any one of claims 1 to 5, further comprising a pressure detection member arranged inside the cavity (20) for detecting the pressure inside the cavity (20).

9. A pipetting mechanism comprising a tip grabbing assembly as claimed in any one of claims 1 to 8.