CN219424446U

CN219424446U - Tumor liquid biopsy device

Info

Publication number: CN219424446U
Application number: CN202320811203.3U
Authority: CN
Inventors: 高海霞; 王孟博; 李新霞
Original assignee: Third Affiliated Hospital of Xinjiang Medical University
Current assignee: Third Affiliated Hospital of Xinjiang Medical University
Priority date: 2023-04-13
Filing date: 2023-04-13
Publication date: 2023-07-28
Anticipated expiration: 2033-04-13

Abstract

The utility model discloses a tumor liquid biopsy device, which belongs to the technical field of medical instruments, and comprises a bottom plate, wherein the top end of the bottom plate is rotationally connected with a placement table, the outer end of the placement table is fixedly connected with an outer gear ring, the top end of the bottom plate is provided with a second motor, the output end of the second motor is provided with a gear meshed with the outer gear ring, the top of the placement table is provided with a lifting plate, the bottom end of the lifting plate is rotationally connected with a sealing plate, the top end of the bottom plate is provided with a driving assembly, the driving assembly can drive the lifting plate to move through the first motor, so that the sealing plate is abutted against the top ends of a plurality of test tubes, the test tubes apply downward pressure to a supporting block, compress a first spring until the sealing plate is contacted with the top ends of the placement table, and then the test tubes are in sealing contact with the sealing plate through the elastic force of the first spring, so that the sealing effect of sealing a plurality of test tubes with different specifications is achieved, and the application range of the device is enlarged.

Description

Tumor liquid biopsy device

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a tumor liquid biopsy device.

Background

Tumor fluid biopsy devices are devices for detecting biomarkers of tumor DNA, RNA, and proteins, which can be used for tumor diagnosis and monitoring in a non-invasive manner, such as blood, urine, and other body fluids. In the tumor liquid biopsy process, the tumor liquid in the test tube needs to be separated and detected.

Chinese patent grant bulletin number: CN213345736U discloses a tumor liquid biopsy device, this scheme has strengthened the protection to the test tube through reset spring's setting, cause liquid to throw away when avoiding the separation, but the application range of this structure receives the restriction, can only seal and fix to a plurality of test tubes of same specification, when need separate a plurality of and test tube of different specifications, the sealing block in this structure can't carry out the contact extrusion with the test tube of wherein length is shorter, thereby can't seal the test tube of length is shorter, and the test tube of length is not obtained effectual fixedly in the standing groove, influence the separation effect of tumor liquid.

Thus, a tumor liquid biopsy device is proposed against the above-mentioned problems.

Disclosure of Invention

1. Technical problem to be solved

Aiming at the problems in the prior art, the utility model aims to provide a tumor liquid biopsy device, which can drive a lifting plate to move through a first motor, so that a sealing plate is abutted against the top ends of a plurality of test tubes, the test tubes apply downward pressure to a supporting block and compress a first spring until the sealing plate is stopped after being contacted with the top ends of a placing table, and at the moment, the top parts of the test tubes are in sealing contact with the sealing plate by the elastic force of the first spring, thereby achieving the effect of sealing a plurality of test tubes with different specifications at the same time, and expanding the application range of the device.

2. Technical proposal

In order to solve the problems, the utility model adopts the following technical scheme.

The utility model provides a tumour liquid biopsy device, includes the bottom plate, the top of bottom plate rotates and is connected with places the platform, the outer fixedly connected with outer ring gear of placing the platform, the second motor is installed on the top of bottom plate, the gear of being connected with outer ring gear meshing is installed to the output of second motor, the top of placing the platform is equipped with the lifter plate, the bottom of lifter plate rotates and is connected with the closing plate, the top of bottom plate is equipped with drive assembly, a plurality of standing grooves have been seted up to the inside of placing the platform, the inside sliding connection of standing groove has the supporting shoe, the top of supporting shoe is equipped with spacing subassembly, drives the lifter plate through first motor for closing plate and a plurality of test tube top looks butt, and downward pressure is applyed to the supporting shoe to the test tube, and stops after the top contact of closing plate and placing the platform, receives the elasticity of first spring so that top and closing plate sealing contact, reaches the effect of sealing up to a plurality of different specifications simultaneously, enlarges the application scope of device.

Further, the first spring is installed to the inner of standing groove, the upper end and the supporting shoe fixed connection of first spring, the first spring of setting can apply ascending elasticity for the test tube for test tube and closing plate in close contact.

Further, the drive assembly includes first motor, first motor is fixed to the top of bottom plate, the screw rod is installed to the output of first motor, the internally mounted of lifter plate has the swivel nut, the outer periphery to the screw rod is established to the swivel nut movable sleeve, realizes the removal of lifter plate vertical direction.

Further, the drive assembly still includes the slide bar, the top to the bottom plate is fixed to the slide bar, the through-hole with slide bar looks adaptation has been seted up to the inside of lifter plate, the slide bar activity runs through in the through-hole, can restrict the motion track of lifter plate, guarantees that the lifter plate can be at vertical direction steady movement.

Further, spacing subassembly includes the stopper, the stopper is fixed to the top of supporting shoe through a plurality of bracing pieces, the blotter is installed on the top of supporting shoe, plays the effect to test tube buffering.

Further, the inside of stopper has been seted up and has been placed the hole, a plurality of spring grooves have been seted up to the inside of stopper, the inside sliding connection in spring groove has the movable block, the second spring is installed to the inner wall in spring groove, the one end and the movable block fixed connection of second spring, the one end of movable block extends to the inner chamber of placing the hole and installs spacing wheel, receives the elasticity and the test tube outer wall looks butt of second spring through the spacing wheel that sets up, reaches the effect to the test tube is spacing, improves the separation effect of device.

3. Advantageous effects

Compared with the prior art, the utility model has the advantages that:

(1) This scheme drives the lifter plate through first motor and removes for closing plate and a plurality of test tube top looks butt, and the test tube applies decurrent pressure for the supporting shoe, and compresses first spring, stop after until the closing plate with place the top contact of platform, the test tube receives the elasticity of first spring and makes top and closing plate sealing contact this moment, reaches the effect that seals up simultaneously a plurality of test tubes of different specifications, enlarges the application range of device.

(2) The limiting wheel is abutted against the outer wall of the test tube through the elasticity of the second spring, so that the limiting effect on the test tube is achieved, and the separation effect of the device is improved.

Drawings

FIG. 1 is a schematic diagram of the overall structure of the present utility model;

FIG. 2 is a schematic cross-sectional view of the present utility model;

fig. 3 is an enlarged schematic view of the structure of fig. 2 a according to the present utility model.

The reference numerals in the figures illustrate:

1. a bottom plate; 2. a placement table; 3. a lifting plate; 4. a placement groove; 5. a first spring; 6. a support block; 7. a limit component; 701. a support rod; 702. a limiting block; 703. a moving block; 704. a limiting wheel; 705. a spring groove; 706. a second spring; 8. a drive assembly; 801. a first motor; 802. a screw; 803. a slide bar; 9. a gear; 10. a second motor; 11. an outer ring gear; 12. and (5) sealing the plate.

Detailed Description

The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model; it is apparent that the described embodiments are only some embodiments of the present utility model, not all embodiments, and that all other embodiments obtained by persons of ordinary skill in the art without making creative efforts based on the embodiments in the present utility model are within the protection scope of the present utility model.

In the description of the present utility model, it should be noted that the positional or positional relationship indicated by the terms such as "upper", "lower", "inner", "outer", "top/bottom", etc. are based on the positional or positional relationship shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "configured to," "engaged with," "connected to," and the like are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

Examples:

referring to fig. 1-3, a tumor liquid biopsy device comprises a bottom plate 1, a placing table 2 is rotationally connected to the top end of the bottom plate 1, an outer gear ring 11 is fixedly connected to the outer end of the placing table 2, a second motor 10 is installed on the top end of the bottom plate 1, a gear 9 in meshed connection with the outer gear ring 11 is installed at the output end of the second motor 10, the gear 9 is controlled to rotate by the second motor 10, the rotation of the placing table 2 is realized under the meshed connection effect of the gear 9 and the outer gear ring 11, at the moment, a sealing plate 12 synchronously rotates along with the placing table 2, tumor liquid in a test tube is separated, a lifting plate 3 is arranged at the top of the placing table 2, a sealing plate 12 is rotationally connected to the bottom end of the lifting plate 3, the sealing plate 12 can be abutted to the top end of the placing table 2, the top of bottom plate 1 is equipped with actuating assembly 8, a plurality of standing grooves 4 have been seted up to the inside of placing table 2 for place tumour liquid test tube, the inside sliding connection of standing groove 4 has supporting shoe 6, the top of supporting shoe 6 is equipped with spacing subassembly 7, play the effect to test tube protection, drive lifter plate 3 through first motor 801 and remove, make closing plate 12 and a plurality of test tube top looks butt, the test tube is for supporting shoe 6 applys decurrent pressure, and compress first spring 5, until closing plate 12 stops after the top contact of placing table 2, the test tube receives the elasticity of first spring 5 at this moment and makes top and closing plate 12 sealing contact, reach the effect that seals up to the test tube of a plurality of different specifications simultaneously, the application range of expanding device.

Referring to fig. 2, a first spring 5 is mounted at the inner end of the placement groove 4, the upper end of the first spring 5 is fixedly connected with a supporting block 6, and the first spring 5 can squeeze the supporting block 6, so that test tubes with different lengths are sealed.

The drive assembly 8 includes first motor 801, first motor 801 is fixed to the top of bottom plate 1, screw rod 802 is installed to the output of first motor 801, the internally mounted of lifter plate 3 has the swivel nut, the outer periphery to screw rod 802 is established to the swivel nut movable sleeve, drive assembly 8 still includes slide bar 803, the top to bottom plate 1 is fixed to the slide bar 803, the through-hole with slide bar 803 looks adaptation is seted up to the inside of lifter plate 3, slide bar 803 activity runs through in the through-hole, through the first motor 801 that sets up, control screw rod 802 takes place to rotate, drive lifter plate 3 and remove for closing plate 12 and a plurality of test tube top looks butt.

Referring to fig. 2, the limiting assembly 7 includes a limiting block 702, the limiting block 702 is fixed to the top end of the supporting block 6 through a plurality of supporting rods 701, and a cushion pad is mounted on the top end of the supporting block 6.

Referring to fig. 2-3, a placement hole is formed in the stopper 702, a plurality of spring grooves 705 are formed in the stopper 702, a moving block 703 is slidably connected in the spring grooves 705, a second spring 706 is mounted on the inner wall of the spring groove 705, one end of the second spring 706 is fixedly connected with the moving block 703, one end of the moving block 703 extends to the inner cavity of the placement hole and is provided with a limiting wheel 704, when a test tube is inserted into the placement groove 4, the limiting wheel 704 is automatically moved towards the outer end direction of the test tube by extrusion, and when the bottom of the test tube contacts with the supporting block 6, the limiting wheel 704 is abutted against the outer wall of the test tube by the elastic force of the second spring 706, so that the limiting effect on the test tube is achieved, and the test tube fixing device can be suitable for fixing test tubes of different specifications.

Working principle: when the tumor liquid in the test tube needs to be separated and detected in the tumor liquid biopsy process, the test tube with the tumor liquid and different lengths is respectively inserted into the inner cavities of the plurality of placing grooves 4 and penetrates through the placing holes in the middle of the limiting block 702, the bottom of the test tube is in contact with the supporting block 6, at the moment, the limiting wheel 704 is abutted against the outer wall of the test tube by the elastic force of the second spring 706, the effect of limiting the test tube is achieved, then the first motor 801 is started, the control screw 802 rotates to drive the lifting plate 3 to move, the sealing plate 12 is abutted against the top ends of the plurality of test tubes, the test tube applies downward pressure to the supporting block 6 and compresses the first spring 5 until the sealing plate 12 is in contact with the top ends of the placing table 2, the first motor 801 stops working, at the moment, the test tube is in sealing contact with the sealing plate 12 by the elastic force of the first spring 5, the effective sealing effect is achieved, at last, the second motor 10 is started to control the rotation of the gear 9, the rotation of the placing table 2 is realized under the meshing connection effect of the gear 9 and the outer gear 11, at the moment, the sealing plate 12 rotates synchronously with the placing table 2, the tumor liquid in the test tube is separated.

The above description is only of the preferred embodiments of the present utility model; the scope of the utility model is not limited in this respect. Any person skilled in the art, within the technical scope of the present disclosure, may apply to the present utility model, and the technical solution and the improvement thereof are all covered by the protection scope of the present utility model.

Claims

1. A tumor liquid biopsy device comprising a base plate (1), characterized in that: the top of bottom plate (1) rotates and is connected with places platform (2), the outer fixedly connected with outer ring gear (11) of placing platform (2), second motor (10) are installed on the top of bottom plate (1), gear (9) are installed with outer ring gear (11) meshing connection to the output of second motor (10), the top of placing platform (2) is equipped with lifter plate (3), the bottom of lifter plate (3) rotates and is connected with closing plate (12), the top of bottom plate (1) is equipped with drive assembly (8), a plurality of standing grooves (4) have been seted up to the inside of placing platform (2), the inside sliding connection of standing groove (4) has supporting shoe (6), the top of supporting shoe (6) is equipped with spacing subassembly (7).

2. The tumor fluid biopsy device of claim 1, wherein: the inner end of the placing groove (4) is provided with a first spring (5), and the upper end of the first spring (5) is fixedly connected with the supporting block (6).

3. The tumor fluid biopsy device of claim 1, wherein: the driving assembly (8) comprises a first motor (801), the first motor (801) is fixed to the top end of the bottom plate (1), a screw (802) is installed at the output end of the first motor (801), a screw sleeve is installed in the lifting plate (3), and the screw sleeve is movably sleeved to the outer periphery of the screw (802).

4. A tumor fluid biopsy device according to claim 3, wherein: the driving assembly (8) further comprises a sliding rod (803), the sliding rod (803) is fixed to the top end of the bottom plate (1), a through hole matched with the sliding rod (803) is formed in the lifting plate (3), and the sliding rod (803) movably penetrates through the through hole.

5. The tumor fluid biopsy device of claim 1, wherein: the limiting assembly (7) comprises a limiting block (702), the limiting block (702) is fixed to the top end of the supporting block (6) through a plurality of supporting rods (701), and a buffer cushion is installed on the top end of the supporting block (6).

6. The tumor fluid biopsy device of claim 5, wherein: the inside of stopper (702) has been seted up and has been placed the hole, a plurality of spring grooves (705) have been seted up to the inside of stopper (702), the inside sliding connection in spring groove (705) has movable block (703), second spring (706) are installed to the inner wall in spring groove (705), the one end and the movable block (703) fixed connection of second spring (706), the one end of movable block (703) extends to the inner chamber of placing the hole and installs spacing wheel (704).