CN219424406U - Synthesis equipment of radiopharmaceuticals - Google Patents

Abstract

The utility model discloses a synthesis device of a radioactive drug, which comprises a shielding box, wherein the shielding box comprises an upper box body and a lower box body, the upper end of the lower box body is connected with the lower end of the upper box body in a threaded manner, a groove for installing a reaction tube is formed in the lower box body, a first baffle plate and a second baffle plate are sequentially arranged in the upper box body from bottom to top, a sealing plate is arranged on the lower surface of the first baffle plate and is used for sealing the top opening of the reaction tube, a plurality of charging ports are arranged on the sealing plate, each charging port is connected with a raw material bottle through a charging tube respectively, an exhaust port is further arranged on the sealing plate and is connected with an exhaust gas treatment device through an exhaust pipe, an exhaust control valve is arranged on the exhaust pipe, a driving motor is arranged on the first baffle plate, an output shaft of the driving motor is connected with a stirring shaft, and the stirring shaft penetrates the sealing plate and extends downwards into the reaction tube. The utility model can treat radioactive waste gas while preparing radiopharmaceuticals, thereby avoiding environmental pollution and radiation injury to personnel.

Description

Synthesis equipment of radiopharmaceuticals

Technical Field

The utility model relates to the technical field of preparation of radiopharmaceuticals, in particular to a synthesis device of a radiopharmaceuticals.

Background

The radiopharmaceuticals refer to a special medicine containing radionuclides for medical diagnosis and treatment, and are compounds or biological agents containing the radionuclides for medical diagnosis or treatment in organisms, the radiopharmaceuticals have to meet pharmacopeia requirements like general medicines, and the types of emitted nuclear rays, energy and radioactive half-lives of the radiopharmaceuticals have certain requirements according to diagnosis and treatment requirements, so that a radiopharmaceuticals synthesis device is needed.

Patent CN216321958U discloses an automatic synthesis device of radiopharmaceuticals, which is characterized in that materials to be synthesized are introduced into the reaction box through an injection port, and a stirring shaft is driven by a starting motor to stir the materials in the reaction box, so that medicines introduced into the reaction box are fused better, and the required radiopharmaceuticals are obtained. However, some radioactive waste gases are generated during the synthesis of radiopharmaceuticals, and the above synthesis apparatus does not take into account the treatment of the radioactive waste gases, and if untreated radioactive waste gases are discharged to the outside environment, the environment is polluted and radiation damage is caused to the medicine preparation staff.

Disclosure of Invention

The utility model aims to provide a synthesis device of a radioactive drug, which solves the problems in the prior art, can treat radioactive waste gas while preparing the radioactive drug, and avoids environmental pollution and radiation damage to personnel.

In order to achieve the above object, the present utility model provides the following solutions:

the utility model provides a synthesis device of a radiopharmaceuticals, which comprises a shielding box, wherein the shielding box comprises an upper box body and a lower box body, the upper end of the lower box body is in threaded connection with the lower end of the upper box body, a groove for installing a reaction tube is formed in the lower box body, a first partition plate and a second partition plate are sequentially arranged in the upper box body from bottom to top, a sealing plate is arranged on the lower surface of the first partition plate and is used for sealing a top opening of the reaction tube, a plurality of charging holes are formed in the sealing plate, each charging hole is connected with a raw material bottle through a charging tube, a charging pump and a charging control valve are respectively arranged on each charging tube, an exhaust port is further formed in the sealing plate and is connected with an exhaust gas treatment device through an exhaust pipe, an exhaust gas control valve is arranged on the exhaust pipe, the exhaust gas treatment device is arranged on the second partition plate, a driving motor is arranged on the first partition plate, an output shaft of the driving motor is connected with a stirring shaft, and the stirring shaft extends downwards into the reaction tube through the sealing plate.

Preferably, the exhaust gas treatment device comprises a liquid nitrogen box, a condensing pipe is arranged in the liquid nitrogen box, and the exhaust pipe penetrates through the condensing pipe and stretches into the bottom in the condensing pipe.

Preferably, the lower surface of the sealing plate is provided with a circle of sealing gasket which is used for being in extrusion sealing connection with the end face of the pipe orifice of the reaction pipe.

Preferably, the gasket is a rubber gasket.

Preferably, a heating space is arranged between the groove and the lower box body, a heating rod is arranged in the heating space, and the reaction tube is heated by the heating rod to provide the temperature required by the reaction.

Preferably, the upper box body is connected with a supporting frame.

Preferably, the stirring shaft is provided with a spiral stirring blade.

Compared with the prior art, the utility model has the following technical effects:

the utility model provides a synthesis device of a radioactive drug, which is characterized in that after a reaction tube is arranged in a groove, a lower box body is connected with the lower end of an upper box body in a threaded manner, the top opening of the reaction tube is sealed through a sealing plate, raw materials in a raw material bottle are added into the reaction tube through a feed pump and a feed control valve, a stirring shaft is driven by a driving motor to stir and react the raw materials to obtain the required radioactive drug, and radioactive waste gas generated by the reaction enters a waste gas treatment device through an exhaust pipe to be treated, so that the radioactive waste gas is prevented from being discharged to the external environment, and the pollution to the environment and the radiation damage to personnel are avoided.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of a radiopharmaceutical synthesis apparatus in accordance with the present utility model;

in the figure: 1-shielding box, 2-upper box, 3-lower box, 4-reaction tube, 5-groove, 6-first baffle, 7-second baffle, 8-sealing plate, 9-feed inlet, 10-feed tube, 11-raw material bottle, 12-feed pump, 13-feed control valve, 14-exhaust port, 15-exhaust pipe, 16-exhaust treatment device, 17-exhaust control valve, 18-driving motor, 19-stirring shaft, 20-liquid nitrogen box, 21-condensing tube, 22-sealing gasket, 23-heating space, 24-heating rod, 25-support frame and 26-spiral stirring blade.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

The utility model aims to provide a synthesis device of a radioactive drug, which solves the problems in the prior art, can treat radioactive waste gas while preparing the radioactive drug, and avoids environmental pollution and radiation damage to personnel.

In order that the above-recited objects, features and advantages of the present utility model will become more readily apparent, a more particular description of the utility model will be rendered by reference to the appended drawings and appended detailed description.

As shown in fig. 1, this embodiment provides a radiopharmaceuticals synthesis apparatus, including a shielding box 1, the shielding box 1 includes an upper box 2 and a lower box 3, the upper end threaded connection of the lower box 3 is at the lower extreme of the upper box 2, a groove 5 for installing a reaction tube 4 is provided in the lower box 3, a first partition 6 and a second partition 7 are sequentially provided in the upper box 2 from bottom to top, a sealing plate 8 is provided on the lower surface of the first partition 6, the sealing plate 8 is used for sealing the top opening of the reaction tube 4, a plurality of feed inlets 9 are provided on the sealing plate 8, each feed inlet 9 is connected with a raw material bottle 11 through a feed tube 10, a feed pump 12 and a feed control valve 13 are provided on each feed tube 10, an exhaust port 14 is also provided on the sealing plate 8, an exhaust port 16 is connected with an exhaust gas treatment device 16 through an exhaust pipe 15, an exhaust gas control valve 17 is provided on the exhaust pipe 15, the exhaust gas treatment device 16 is installed on the second partition 7, a driving motor 18 is installed on the first partition 6, an output shaft of the driving motor 18 is connected with a stirring shaft 19, and the stirring shaft 19 extends downward into the reaction tube 4 through the sealing plate 8.

When the radioactive waste gas treatment device is used, after the reaction tube 4 is installed in the groove 5, the lower box body 3 is in threaded connection with the lower end of the upper box body 2, the top opening of the reaction tube 4 is sealed through the sealing plate 8, then raw materials in the raw material bottle 11 are added into the reaction tube 4 through the feeding pump 12 and the feeding control valve 13, the raw material bottle 11 is arranged on the second partition plate 7, the stirring shaft 19 is driven by the driving motor 18 to stir the reaction raw materials, the required radioactive medicament is obtained, radioactive waste gas generated by the reaction enters the waste gas treatment device 16 through the exhaust pipe 15 to be treated, so that the radioactive waste gas is prevented from being discharged to the external environment, and the pollution to the environment and the radiation damage to personnel are avoided. Due to the detachable design of the upper box body 2 and the lower box body 3, the reaction tube 4 is convenient to install and take out, and the raw materials in the corresponding raw material bottle 11 can be selected for adding according to the medicines to be prepared through the plurality of charging ports 9 arranged on the sealing plate 8, the corresponding charging tubes 10 and the raw material bottles 11, so that the preparation method can be suitable for preparing various medicines and is very convenient to use.

In this embodiment, the exhaust gas treatment device 16 includes a liquid nitrogen tank 20, a condensation pipe 21 is disposed in the liquid nitrogen tank 20, and the exhaust pipe 15 extends into the bottom of the condensation pipe 21 through the condensation pipe 21. The radioactive waste gas generated by the reaction enters the condensing tube 21 and is condensed into radioactive waste liquid in the low-temperature environment of liquid nitrogen, the radioactive waste liquid is stored in the condensing tube 21, and after the radioactive waste liquid decays to a certain dosage, the radioactive waste liquid can be directly discharged into a decay tank.

In this embodiment, a ring of sealing gasket 22 is provided on the lower surface of the sealing plate 8, and the sealing gasket 22 is used for extrusion sealing connection with the end face of the nozzle of the reaction tube 4. In this embodiment, the gasket 22 is a rubber gasket. After the upper box body 2 and the lower box body 3 are connected through threads, the sealing gasket 22 forms extrusion sealing on the end face of the pipe orifice of the reaction pipe 4, so that the sealing effect is ensured.

In this embodiment, a heating space 23 is provided between the groove 5 and the lower case 3, a heating rod 24 is provided in the heating space 23, and the reaction tube 4 is heated by the heating rod 24 to provide a temperature required for the reaction.

In this embodiment, the upper case 2 is connected with a supporting frame 25, and the upper case 2 is supported by the supporting frame 25, and the lower case 3 is convenient to be disassembled from the bottom.

In this embodiment, the stirring shaft 19 is provided with a spiral stirring blade 26, and the reaction raw materials are uniformly stirred by the spiral stirring blade 26, so that the fusion reaction of the reaction raw materials is better performed.

The principles and embodiments of the present utility model have been described in detail with reference to specific examples, which are provided to facilitate understanding of the method and core ideas of the present utility model; also, it is within the scope of the present utility model to be modified by those of ordinary skill in the art in light of the present teachings. In view of the foregoing, this description should not be construed as limiting the utility model.

Claims (7)

1. A radiopharmaceutical synthesis apparatus, comprising: including the shielding case, the shielding case includes box and lower box down, lower box upper end threaded connection is in go up the box lower extreme, be equipped with the recess that is used for installing the reaction tube in the box down, upward be equipped with first baffle and second baffle in proper order by supreme down in the box, first baffle lower surface is equipped with the closing plate, the closing plate is used for sealedly the open-top of reaction tube, be equipped with a plurality of charge door on the closing plate, each the charge door has a raw materials bottle through a charging tube connection respectively, each all set up a charge pump and a charge control valve on the charging tube, still be equipped with the gas vent on the closing plate, the gas vent passes through blast pipe connection exhaust treatment device, be equipped with the exhaust control valve on the blast pipe, exhaust treatment device installs on the second baffle, install driving motor on the first baffle, driving motor's output shaft stirring axle, the stirring axle passes the closing plate downwardly extending extremely in the reaction tube.

2. The radiopharmaceutical synthesis apparatus of claim 1, wherein: the waste gas treatment device comprises a liquid nitrogen box, a condensing pipe is arranged in the liquid nitrogen box, and the exhaust pipe penetrates through the condensing pipe and stretches into the bottom in the condensing pipe.

3. The radiopharmaceutical synthesis apparatus of claim 1, wherein: the lower surface of the sealing plate is provided with a circle of sealing gasket which is used for being in extrusion sealing connection with the end face of the pipe orifice of the reaction pipe.

4. A radiopharmaceutical synthesis apparatus according to claim 3 wherein: the sealing gasket is a rubber sealing gasket.

5. The radiopharmaceutical synthesis apparatus of claim 1, wherein: a heating space is arranged between the groove and the lower box body, a heating rod is arranged in the heating space, and the reaction tube is heated by the heating rod to provide the temperature required by the reaction.

6. The radiopharmaceutical synthesis apparatus of claim 1, wherein: the upper box body is connected with a supporting frame.

7. The radiopharmaceutical synthesis apparatus of claim 1, wherein: the stirring shaft is provided with a spiral stirring blade.