CN219423785U

CN219423785U - DNA purifying column

Info

Publication number: CN219423785U
Application number: CN202222639661.1U
Authority: CN
Inventors: 徐华; 朱树勇
Original assignee: Jiangsu Biyuntian High Tech Co ltd
Current assignee: Jiangsu Biyuntian High Tech Co ltd
Priority date: 2022-10-09
Filing date: 2022-10-09
Publication date: 2023-07-28
Anticipated expiration: 2032-10-09

Abstract

The utility model discloses a DNA purifying column, which belongs to the field of DNA detection, and comprises a base and a purifying column tube, wherein a placing hole is formed in the front side of the upper end of the base, the size of the placing hole is matched with that of the purifying column tube, the purifying column tube is placed in the placing hole, an auxiliary block fixedly connected with the upper end face of the base is arranged on the rear side of the placing hole, through holes are formed in the rear side of the auxiliary block, elastic rotating shafts which are rotationally connected in the vertical direction are arranged on the left side and the right side of the through holes, the upper ends of the elastic rotating shafts penetrate through the upper end face of the auxiliary block and are fixedly connected with auxiliary handles, a pair of gears which are placed left and right are arranged on the lower ends of the through holes, Z-shaped toothed plates are connected between the pair of gears in a meshed mode, support plates are fixedly connected to the middle sections of the elastic rotating shafts, and the support plates play a role of supporting the whole purifying column tube, and are convenient for a user to extract and refine DNA in the purifying column tube, so that the stability of the purifying column tube is improved, and the purifying speed is accelerated.

Description

DNA purifying column

Technical Field

The utility model relates to the field of DNA detection, in particular to a DNA purification column.

Background

The DNA purifying column can be used for extracting and refining DNA of various materials, has the characteristics of simple operation, high recovery rate, stable performance and the like, and is used for most laboratories and companies at home and abroad at present. The DNA purification column adopts a silica gel film as a specific adsorption material of nucleic acid, and basically does not adsorb other biological materials, so that the maximum recovery of DNA in a sample can be ensured, and other impurities can be removed.

The existing purification column for purifying DNA is not convenient enough when using, when carrying out DNA extraction, often is a handheld purification column of alone left hand, and DNA gathers in the right hand, and purification column is whole cylindrical, and the lower extreme is circular arc structure, this structural feature for purification column places unstably, and purification column takes place to empty the possibility increase, consequently in special environment, needs a novel DNA purification column, solves the DNA collection under the special condition.

Disclosure of Invention

1. Technical problem to be solved

Aiming at the problems in the prior art, the utility model aims to provide a DNA purifying column, when the purifying column tube is used, the purifying column tube is placed in the placing hole, so that the whole purifying column tube is supported, and meanwhile, a user can conveniently extract and refine DNA in the purifying column tube, the stability of the purifying column tube is improved, and the purifying speed is increased.

2. Technical proposal

In order to solve the problems, the utility model adopts the following technical scheme.

The utility model provides a DNA purification post, includes base and purification post body, the hole of placing has been seted up to base upper end front side, and place the hole size and purification post body phase-match, purification post body is placed in placing downthehole, place the hole rear side be provided with base up end fixed connection's auxiliary block, the through-hole has been seted up to auxiliary block rear side, the through-hole left and right sides all is provided with the elasticity pivot that vertical direction rotated and is connected, elasticity pivot upper end runs through auxiliary block up end and fixedly connected with auxiliary handle, the through-hole lower extreme is provided with a pair of gear of placing about, and elasticity pivot lower extreme extends to in the gear and with the interior ring interference fit of gear, a pair of meshing is connected with Z type pinion rack between the gear, a pair of equal fixedly connected with backplate in elasticity pivot middle part, and backplate bulk length all are shorter than through-hole length, when using purification post body, place purification post body in placing downthehole, when playing the whole effect to purification post body, the user draws and refines with purification post body internal DNA, thereby is favorable to improving purification stability.

Further, the movable sliding groove is formed in the bottom wall of the through hole, the sliding block is connected in the movable sliding groove in a sliding mode, the upper end of the sliding block is fixedly connected with the lower end of the Z-shaped toothed plate, the sliding block is located at the middle position of the Z-shaped toothed plate, the sliding block and the sliding groove are matched with each other, the Z-shaped toothed plate can be driven to move more stably, and therefore meshing transmission between the Z-shaped toothed plate and a gear is more stable.

Further, Z type pinion rack includes first pinion rack and the second pinion rack of front and back distribution, through connecting plate fixed connection between first pinion rack right-hand member and the second pinion rack left end, meshing connection between first pinion rack and the left side gear front end, meshing connection between second pinion rack and the right side gear rear end only need rotate one of them elasticity pivot, and elasticity pivot drives the gear rotation to drive Z type pinion rack overall movement, meshing transmission's drive force between Z type pinion rack and the gear makes a pair of gear rotate towards opposite direction, thereby makes and a pair of backplate expand.

Further, the whole arc that is of backplate, and a pair of backplate are close to one side each other and have seted up the arc recess, fixedly connected with sponge bed course on the arc recess, the backplate plays the supporting role to the purification column body, and arc recess and purification column body outer structure assorted have further strengthened spacing and support to the purification column body simultaneously.

Further, the outside cover of elastic rotating shaft is equipped with spacing swivel, and fixed connection between spacing swivel and the through-hole roof, and spacing swivel has strengthened elastic rotating shaft pivoted stability on the one hand, forces elastic rotating shaft to steadily rotate in the horizontal direction, plays on the other hand to elastic rotating shaft pivoted limiting displacement.

Further, the receiver of fixed connection is provided with between auxiliary block front side and the base up end, the standing groove has been seted up in the receiver, the receiver front side rotates and is connected with standing groove assorted apron, and the standing groove is used for placing unused articles such as cotton swab for sampling, and the arc recess plays dustproof effect to articles in the standing groove.

3. Advantageous effects

Compared with the prior art, the utility model has the advantages that:

(1) This scheme is when using the purification column body, places the purification column body in placing the hole, when playing the supporting role to purification column body is whole, and the user draws and refines the internal DNA of purification column body, is favorable to improving the stability of purification column body to accelerate purification rate.

(2) The movable sliding groove is formed in the bottom wall of the through hole, the sliding block is connected in the movable sliding groove in a sliding mode, the upper end of the sliding block is fixedly connected with the lower end of the Z-shaped toothed plate, the sliding block is located at the middle position of the Z-shaped toothed plate, and the sliding block and the sliding groove are matched with each other, so that the Z-shaped toothed plate can be driven to move more stably, and meshing transmission between the Z-shaped toothed plate and the gear is more stable.

(3) The Z-shaped toothed plate comprises a first toothed plate and a second toothed plate which are distributed front and back, the right end of the first toothed plate is fixedly connected with the left end of the second toothed plate through a connecting plate, the front ends of the first toothed plate and the left side gears are in meshed connection, the rear ends of the second toothed plate and the right side gears are in meshed connection, only one elastic rotating shaft is required to rotate, the elastic rotating shaft drives the gears to rotate, so that the Z-shaped toothed plate is driven to integrally move, and a pair of gears rotate in opposite directions due to meshed driving force between the Z-shaped toothed plate and the gears, so that a pair of support plates are unfolded.

(4) The whole arc that is of backplate, and a pair of backplate are close to one side each other and have seted up the arc recess, fixedly connected with sponge bed course on the arc recess, and the backplate plays the supporting role to purification column body, and arc recess and purification column body external structure assorted have further strengthened spacing and support to the purification column body simultaneously.

(5) The elastic rotating shaft is sleeved with the limiting rotating ring outside, the limiting rotating ring is fixedly connected with the top wall of the through hole, on one hand, the stability of rotation of the elastic rotating shaft is enhanced, the elastic rotating shaft is forced to rotate stably in the horizontal direction, and on the other hand, the limiting effect on rotation of the elastic rotating shaft is achieved.

(6) The receiver of fixed connection between auxiliary block front side and the base up end has been provided with the standing groove in the receiver, and the receiver front side rotates to be connected with standing groove assorted apron, and the standing groove is used for placing articles such as unused sampling cotton swab, and the arc recess plays dustproof effect to the article in the standing groove.

Drawings

FIG. 1 is a schematic view of the present utility model in use;

FIG. 2 is a schematic view of the structure of the present utility model when not in use;

FIG. 3 is an internal cross-sectional view of an auxiliary block of the present utility model;

FIG. 4 is a schematic view of the support plate of the present utility model when retracted;

FIG. 5 is a schematic view showing the structure of the support plate of the present utility model when it is unfolded.

The reference numerals in the figures illustrate:

1. a base; 2. placing the hole; 3. purifying the column tube body; 4. a storage box; 5. a cover plate; 6. a support plate; 7. an auxiliary handle; 8. an auxiliary block; 9. a Z-shaped toothed plate; 901. a first toothed plate; 902. a second toothed plate; 903. a connecting plate; 11. an elastic rotating shaft; 12. a gear; 13. a slide block; 14. a limiting swivel; 15. an arc-shaped groove.

Detailed Description

The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model; it is apparent that the described embodiments are only some embodiments of the present utility model, not all embodiments, and that all other embodiments obtained by persons of ordinary skill in the art without making creative efforts based on the embodiments in the present utility model are within the protection scope of the present utility model.

In the description of the present utility model, it should be noted that the positional or positional relationship indicated by the terms such as "upper", "lower", "inner", "outer", "top/bottom", etc. are based on the positional or positional relationship shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "configured to," "engaged with," "connected to," and the like are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

Example 1:

referring to fig. 1 to 5, a DNA purification column comprises a base 1 and a purification column tube 3, wherein a gasket made of special fiber material is disposed in the purification column tube 3, the gasket contains acid-base resistance and most of organic solvent, and is provided with an inlet silica gel film or glass fiber film which is specially optimized to adsorb nucleic acid molecules to the greatest extent, the structure is the existing structure inside the purification column tube 3, the front side of the upper end of the base 1 is provided with a placement hole 2, the size of the placement hole 2 is matched with that of the purification column tube 3, the rear side of the placement hole 2 is provided with an auxiliary block 8 fixedly connected with the upper end surface of the base 1, the rear side of the auxiliary block 8 is provided with a through hole, the left side and the right side of the through hole are provided with elastic rotating shafts 11 which are connected in a vertical direction, the elastic rotating shafts 11 have the characteristic of automatically recovering after rotating, the upper end of the elastic rotating shaft 11 penetrates through the upper end face of the auxiliary block 8 and is fixedly connected with an auxiliary handle 7, a limiting rotating ring 14 is sleeved outside the elastic rotating shaft 11 and is fixedly connected with the top wall of the through hole, the elastic rotating shaft 11 can be driven to rotate by rotating the auxiliary handle 7, the limiting rotating ring 14 strengthens the rotating stability of the elastic rotating shaft 11 on one hand, forces the elastic rotating shaft 11 to stably rotate in the horizontal direction, on the other hand, a pair of gears 12 which are arranged left and right are arranged at the lower end of the through hole and play a role in limiting the rotating of the elastic rotating shaft 11 are arranged at the lower end of the through hole, the lower end of the elastic rotating shaft 11 extends into the gears 12 and is in interference fit with the inner ring of the gears 12, a pair of gears 12 are in meshed connection with each other, Z-shaped toothed plates 9 are fixedly connected at the middle sections of the pair of the elastic rotating shafts 11, the Z-shaped toothed plates 9 are all shorter than the length of the through hole, the Z-shaped toothed plates 9 comprise a first toothed plate 901 and a second toothed plate 902 which are distributed front and back, the right end of the first toothed plate 901 is fixedly connected with the left end of the second toothed plate 902 through the connecting plate 903, the first toothed plate 901 is connected with the front end of the left gear 12 in a meshed manner, the second toothed plate 902 is connected with the rear end of the right gear 12 in a meshed manner, only one of the elastic rotating shafts 11 is required to rotate, the elastic rotating shafts 11 drive the gears 12 to rotate, thereby driving the Z-shaped toothed plate 9 to integrally move, the driving force of meshed transmission between the Z-shaped toothed plate 9 and the gears 12 enables the pair of gears 12 to rotate in opposite directions, so that the pair of support plates 6 are unfolded, after the support plates 6 are opened, the purifying column tube 3 can be placed in the placing holes 2, specifically, the gears 12 on the left side are driven to rotate anticlockwise, the whole Z-shaped toothed plate 9 can be driven to move leftwards, the gears 12 on the right side are driven to rotate clockwise, or the gears 12 on the right side are driven to rotate clockwise, the whole Z-shaped toothed plate 9 can be driven to move leftwards, the gears 12 on the left side rotate anticlockwise, a movable sliding chute is formed in the through hole, the sliding block 13 is connected with the sliding block 13, and the Z-shaped toothed plate 9 is driven to move with the Z-shaped toothed plate 9, and the Z-shaped toothed plate is positioned between the Z-shaped toothed plate 9 and the Z-shaped toothed plate is more stably matched with the fixed, and the Z-shaped toothed plate is driven to move between the Z-shaped toothed plate 9 and the position.

Referring to fig. 5, the Z-shaped toothed plates 9 are integrally arc-shaped, and an arc-shaped groove 15 is formed in one side of each pair of Z-shaped toothed plates 9, wherein the arc-shaped groove 15 is fixedly connected with a sponge cushion layer, the Z-shaped toothed plates 9 play a role in supporting the purifying column tube 3, and meanwhile, the arc-shaped grooves 15 are matched with the external structure of the purifying column tube 3, so that the limit and the support of the purifying column tube 3 are further enhanced.

Referring to fig. 2, a storage box 4 fixedly connected with the upper end surface of the base 1 is arranged at the front side of the auxiliary block 8, a placing groove is formed in the storage box 4, a cover plate 5 matched with the placing groove is rotatably connected at the front side of the storage box 4, the placing groove is used for placing unused sampling swabs and other objects, and the arc-shaped groove 15 plays a role in dust prevention of the objects in the placing groove.

During the use, rotate one of them auxiliary handle 7, take left side auxiliary handle 7 as the example, manual rotation left side drives elastic rotating shaft 11 anticlockwise rotation, thereby drive left side gear 12 anticlockwise rotation, thereby first pinion rack 901 and left side gear 12 meshing transmission drive whole Z type pinion rack 9 left movement, thereby rotate along clockwise direction of placing under meshing transmission between right side gear 12 and the second pinion rack 902, a pair of elastic rotating shaft 11 rotates in opposite directions, support plate 6 rotates along with elastic rotating shaft 11 and opens, when support plate 6 opens to place the purification column body 3 in place hole 2 outside, the hand loosens, elastic rotating shaft 11 utilizes self elastic rotation's characteristic, thereby support plate 6 withdraws the in-process, arc recess 15 and purification column body 3 outer wall laminating each other, support plate 6 supports purification column body 3, the user can carry out the DNA sample in the purification column body 3, compared with prior art, when using purification column body 3, place purification column body 3 in place hole 2, the purification column body 3 is placed in place, the purification column body 3 is used to the effect is improved to purification column body 3, thereby the whole purification is done to purification column body 3, the purification is improved, and purification is carried out to the purification column body is improved.

The above description is only of the preferred embodiments of the present utility model; the scope of the utility model is not limited in this respect. Any person skilled in the art, within the technical scope of the present disclosure, may apply to the present utility model, and the technical solution and the improvement thereof are all covered by the protection scope of the present utility model.

Claims

1. A DNA purification column comprising a base (1) and a purification column tube (3), characterized in that: the utility model discloses a purification column tube body, including base (1), purification column tube body, through-hole (2), through-hole (8), elastic rotating shaft (11) that vertical direction rotated and was connected are all offered to base (1) upper end front side, and place the size and the purification column tube body (3) phase-match of hole (2), purification column tube body (3) place in placing hole (2), place hole (2) rear side be provided with base (1) up end fixed connection's auxiliary block (8), through-hole left and right sides all is provided with elastic rotating shaft (11) that vertical direction rotated and was connected, elastic rotating shaft (11) upper end runs through auxiliary block (8) up end and fixedly connected with auxiliary handle (7), through-hole lower extreme is provided with a pair of gear (12) of placing about, and elastic rotating shaft (11) lower extreme extend to in gear (12) and with gear (12) inner ring interference fit, a pair of meshing between gear (12) is connected with Z type pinion rack (9), a pair of elastic rotating shaft (11) interlude is all fixedly connected with backplate (6), and backplate (6) overall length is shorter than equal.

2. A DNA purification column according to claim 1, wherein: the movable sliding chute is formed in the bottom wall of the through hole, a sliding block (13) is connected in the movable sliding chute in a sliding mode, the upper end of the sliding block (13) is fixedly connected with the lower end of the Z-shaped toothed plate (9), and the sliding block (13) is located in the middle of the Z-shaped toothed plate (9).

3. A DNA purification column according to claim 1, wherein: the Z-shaped toothed plate (9) comprises a first toothed plate (901) and a second toothed plate (902) which are distributed front and back, the right end of the first toothed plate (901) is fixedly connected with the left end of the second toothed plate (902) through a connecting plate (903), the first toothed plate (901) is connected with the front end of a gear (12) on the left side in a meshed mode, and the second toothed plate (902) is connected with the rear end of the gear (12) on the right side in a meshed mode.

4. A DNA purification column according to claim 1, wherein: the support guard plates (6) are integrally arc-shaped, an arc-shaped groove (15) is formed in one side, close to each other, of each support guard plate (6), and a sponge cushion layer is fixedly connected to the arc-shaped groove (15).

5. A DNA purification column according to claim 1, wherein: the outside of the elastic rotating shaft (11) is sleeved with a limiting rotating ring (14), and the limiting rotating ring (14) is fixedly connected with the top wall of the through hole.

6. A DNA purification column according to claim 1, wherein: the storage box (4) fixedly connected with the upper end face of the base (1) is arranged on the front side of the auxiliary block (8), a placing groove is formed in the storage box (4), and a cover plate (5) matched with the placing groove is rotationally connected to the front side of the storage box (4).