CN219363643U - Reagent detection device and cell analyzer - Google Patents
Reagent detection device and cell analyzer Download PDFInfo
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- CN219363643U CN219363643U CN202320376429.5U CN202320376429U CN219363643U CN 219363643 U CN219363643 U CN 219363643U CN 202320376429 U CN202320376429 U CN 202320376429U CN 219363643 U CN219363643 U CN 219363643U
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 98
- 238000001514 detection method Methods 0.000 title claims abstract description 34
- 230000003287 optical effect Effects 0.000 claims abstract description 43
- 239000007788 liquid Substances 0.000 claims abstract description 21
- 238000003780 insertion Methods 0.000 claims description 5
- 230000037431 insertion Effects 0.000 claims description 5
- 238000012360 testing method Methods 0.000 claims description 5
- 238000004891 communication Methods 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The embodiment of the utility model discloses a reagent detection device and a cell analyzer, wherein the reagent detection device comprises a body part, a first optical coupler sensor and a second optical coupler sensor, wherein the body part is provided with a liquid channel, and an inlet end and an outlet end which are communicated with the liquid channel, so that reagents can flow from the inlet end to the outlet end through the liquid channel.
Description
Technical Field
The utility model relates to the technical field of reagent detection, in particular to a reagent detection device and a cell analyzer.
Background
In cell analyzers, the cell counting process typically requires the use of a variety of reagents for cell lysis, staining, reaction, etc. Therefore, in the cell analyzer, an alarm is often required when the reagent is not available, so as to prompt the user to change the liquid.
At present, whether a detection reagent generally passes through fixed use times or not, and is buckled according to the count execution times, and the alarm is given until the use times become 0 or are close to 0, so that the reagent replacement is prompted, but false alarm can often occur, and meanwhile, if the reagent is replaced halfway, false judgment can be caused, so that the accuracy of judging whether the reagent exists or not is lower.
Disclosure of Invention
Based on this, it is necessary to provide a reagent detecting apparatus and a cell analyzer, which are aimed at solving the technical problems that at present, whether a detection reagent is generally used by a fixed number of times, the detection reagent is buckled according to the counted execution number of times, and an alarm is given to prompt replacement of the reagent until the number of times of use becomes 0 or close to 0, but false alarm often occurs, and if the reagent is replaced halfway, false judgment is caused, and the accuracy of judging whether the reagent is present is low.
In a first aspect, the present utility model provides a reagent detection device, where the reagent detection device includes a body portion, a first optocoupler sensor and a second optocoupler sensor, the body portion is provided with a liquid channel, and an inlet end and an outlet end that are communicated with the liquid channel, the first optocoupler sensor is disposed at the inlet end and is used for sensing a reagent in the inlet end, and the second optocoupler sensor is disposed at the outlet end and is used for sensing a reagent in the outlet end.
In one embodiment, the body portion includes a first portion and a second portion, and a connecting pipe connecting the first portion and the second portion, the inlet end is disposed in the first portion, the outlet end is disposed in the second portion, and an inner cavity of the connecting pipe forms the liquid channel.
In one embodiment, the first portion is formed with a first joint, the second portion is formed with a second joint, one end of the connecting pipeline is inserted into the first joint, and the other end of the connecting pipeline is inserted into the second joint.
In one embodiment, the first portion is further formed with a third connector and the second portion is further formed with a fourth connector, both for connection to an external pipeline.
In one embodiment, the first optocoupler sensor is detachably connected to the first portion and the second optocoupler sensor is detachably connected to the second portion.
In one embodiment, the first portion is formed with a first plugging slot, the first optocoupler sensor is plugged into a slot wall of the first plugging slot, the second portion is formed with a second plugging slot, and the second optocoupler sensor is plugged into a slot wall of the second plugging slot.
In one embodiment, the detection device further comprises an alarm, wherein the alarm has a first alarm state and a second alarm state;
in the first warning state, the first optical coupler sensor and the second optical coupler sensor sense that the reagent generates bubbles;
in the second warning state, the first optocoupler sensor senses that the reagent generates bubbles, and the second optocoupler sensor senses that the reagent does not have bubbles, or the first optocoupler sensor and the second optocoupler sensor both sense that the reagent does not have bubbles.
In one embodiment, the alarm may be a buzzer, and the buzzer may emit sound and not sound, so as to correspond to the first alarm state and the second alarm state.
In one embodiment, the reagent detection device further includes a signal detection unit, where the signal detection unit is communicatively connected to the first optocoupler sensor and the second optocoupler sensor, and is configured to read optocoupler signals of the first optocoupler sensor and the second optocoupler sensor.
In a second aspect, the present utility model also provides a cell analyzer comprising a control panel and the reagent detection device of any of the above embodiments, the control panel being in communication with the reagent detection device.
The implementation of the embodiment of the utility model has the following beneficial effects:
by adopting the reagent detection device and the cell analyzer, when the reagent is detected, the body part is provided with the liquid channel and the inlet end and the outlet end which are communicated with the liquid channel, so that the reagent can flow from the inlet end to the outlet end through the liquid channel.
Drawings
In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the utility model, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Wherein:
FIG. 1 is an isometric view of a reagent testing device according to one embodiment.
Fig. 2 is a schematic diagram showing a first state of a first optocoupler sensor and a second optocoupler sensor of the reagent detecting apparatus according to an embodiment.
Fig. 3 is a schematic diagram showing a second state of the first optocoupler and the second optocoupler of the reagent detecting apparatus according to one embodiment.
Reference numerals: 1. a body portion; 11. a first portion; 111. a first joint; 112. a third joint; 113. a first socket groove; 12. a second portion; 121. a second joint; 122. a fourth joint; 123. a second insertion groove; 13. a connecting pipeline; 2. a first optocoupler sensor; 3. a second optocoupler sensor; 100. a liquid channel; 200. an inlet end; 300. an outlet end.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
In the description of the present utility model, it should be noted that, if the terms "upper", "lower", "inner", "outer", and the like indicate an azimuth or a positional relationship based on the azimuth or the positional relationship shown in the drawings, or the azimuth or the positional relationship in which the inventive product is conventionally put in use, it is merely for convenience of describing the present utility model and simplifying the description, and it is not indicated or implied that the apparatus or element referred to must have a specific azimuth, be configured and operated in a specific azimuth, and thus it should not be construed as limiting the present utility model.
Furthermore, the terms "first," "second," and the like, if any, are used merely for distinguishing between descriptions and not for indicating or implying a relative importance.
It should be noted that the features of the embodiments of the present utility model may be combined with each other without conflict.
Referring to fig. 1 to 3, a reagent testing apparatus according to the present utility model will now be described. The reagent detection device comprises a body part 1, a first optical coupler sensor 2 and a second optical coupler sensor 3, wherein the body part 1 is provided with a liquid channel 100, and an inlet end 200 and an outlet end 300 which are communicated with the liquid channel 100, the first optical coupler sensor 2 is arranged at the inlet end 200 and is used for sensing a reagent in the inlet end 200, and the second optical coupler sensor 3 is arranged at the outlet end 300 and is used for sensing the reagent in the outlet end 300.
Specifically, the reagent can flow from the inlet end 200 to the outlet end 300 through the liquid channel 100, so that the first optocoupler 2 and the second optocoupler 3 can change, in the state of the reagent, the inlet end 200 and the outlet end 300 are continuously flowing reagents, no bubbles are generated, and the first optocoupler 2 and the second optocoupler 3 sense the reagent as low-frequency current in unit time, so that the change of the first optocoupler 2 and the second optocoupler 3 tends to be zero. In the state of no reagent, the inlet end 200 and the outlet end 300 are intermittent flowing reagents, and bubbles are continuously generated, so that the first optocoupler sensor 2 and the second optocoupler sensor 3 sense the reagent as high-frequency current in unit time, and therefore, the change of the first optocoupler sensor 2 and the second optocoupler sensor 3 tends to a preset value, and the preset value is 1 when in implementation.
It can be understood that when the reagent detecting device detects the presence or absence of a reagent, the body portion 1 is provided with the liquid channel 100, and the inlet end 200 and the outlet end 300 which are communicated with the liquid channel 100, so that the reagent can flow from the inlet end 200 to the outlet end 300 through the liquid channel 100.
In this embodiment, the body 1 includes a first portion 11 and a second portion 12, and a connecting tube 13 connecting the first portion 11 and the second portion 12, an inlet end 200 is disposed at the first portion 11, an outlet end 300 is disposed at the second portion 12, and an inner cavity of the connecting tube 13 forms the liquid channel 100. By providing the first portion 11 and the second portion 12, a certain distance can be formed between the inlet end 200 and the outlet end 300, so that the first optocoupler sensor 2 and the second optocoupler sensor 3 can detect whether the reagent has bubbles more accurately.
In one embodiment, as shown in fig. 1, the first portion 11 is formed with a first joint 111, the second portion 12 is formed with a second joint 121, one end of the connecting pipe 13 is plugged into the first joint 111, and the other end of the connecting pipe 13 is plugged into the second joint 121. Specifically, the connecting pipeline 13 is an elastic pipeline, so that the connecting pipeline 13 can be inserted into the first connector 111 and the second connector 121, and when the connecting pipeline 13 is aged, the connecting pipeline 13 is convenient to replace.
Of course, in other embodiments, the first connector 111 and the second connector 121 may be quick connectors, so that the connecting pipeline 13 can be conveniently installed on the first connector 111 and the second connector 121.
In one embodiment, continuing to refer to fig. 1, the first portion 11 is further formed with a third fitting 112 and the second portion 12 is further formed with a fourth fitting 122, both the third fitting 112 and the fourth fitting 122 being adapted for connection to an external conduit. Specifically, the third connector 112 is connected to a reagent bottle for supplying a reagent through an external line, and the fourth connector 122 is connected to a collection bottle through an external line. The outer walls of the third and fourth joints 112 and 122 are formed with waves so that the external pipe is not easily dropped on the third and fourth joints 112 and 122.
Of course, in other embodiments, the third and fourth connectors 112, 122 may be quick connectors to enable an external conduit to be quickly connected to the third and fourth connectors 112, 122.
In one embodiment, continuing with FIG. 1, first optocoupler 2 is removably attached to first portion 11 and second optocoupler 3 is removably attached to second portion 12. In this way, the first optical coupler sensor 2 and the second optical coupler sensor 3 can be conveniently replaced or maintained after being damaged.
In the present embodiment, the first portion 11 is formed with a first plugging slot 113, the first optocoupler 2 is plugged into a slot wall of the first plugging slot 113, the second portion 12 is formed with a second plugging slot 123, and the second optocoupler 3 is plugged into a slot wall of the second plugging slot 123. Through setting up first jack groove 113 and second jack groove 123 for first opto-coupler sensor 2 and second opto-coupler sensor 3 are convenient to dismantle, and then, after first opto-coupler sensor 2 and second opto-coupler sensor 3 damage, convenient maintenance or change.
In one embodiment, as shown in fig. 1 to 3, the detection device further includes an alarm (not shown in the drawings), and the alarm has a first alarm state and a second alarm state.
In the first warning state, the first optical coupler sensor 2 and the second optical coupler sensor 3 sense that the test agent generates bubbles (as shown in fig. 2), and the sensing agent of the first optical coupler sensor 2 and the second optical coupler sensor 3 is high-frequency current and tends to be 1 value. Since air exists due to the generation of the air bubbles, the current of the sensing agent of the first optical coupler sensor 2 and the second optical coupler sensor 3 is changed, and at this time, it is determined that there is no agent.
In the second warning state, the first optocoupler sensor 2 and the second optocoupler sensor 3 both sense that the reagent has no bubbles. The sensing reagents of the first optical coupler sensor 2 and the second optical coupler sensor 3 are low-frequency currents and tend to be 0 value. Since no bubble is generated in the reagent, the first optical coupler sensor 2 and the second optical coupler sensor 3 sense no change in the current of the reagent, and at this time, it is determined that the reagent is present.
In addition, due to the operation of the external environment, discontinuous micro bubbles may be generated, for example, micro bubbles are generated at the inlet end 200 and disappear at the outlet end 300. The first optical coupler sensor 2 senses that the test agent generates bubbles, the second optical coupler sensor 3 senses that the reagent does not generate bubbles (as shown in fig. 3), the first optical coupler sensor 2 senses that the reagent is high-frequency current and tends to be 1 value, and the second optical coupler sensor 3 senses that the reagent is low-frequency current and tends to be 0 value. Therefore, the first optocoupler sensor 2 senses a change in the current of the reagent, and the second optocoupler sensor 3 senses no change in the current of the reagent, and at this time, it is determined that the reagent is present.
In this embodiment, the alarm may be a buzzer, where the buzzer can emit sound and not sound, so as to correspond to the first alarm state and the second alarm state. In a first warning state, i.e. when no reagent is present, the buzzer sounds to prompt the user to replace the reagent. In the second warning state, namely when the reagent exists, the buzzer does not sound and the reagent is not replaced.
Of course, in other embodiments, the warning device and the indicator light can emit red light and green light to correspond to the first warning state and the second warning state. And in the first warning state, namely when no reagent exists, the indicator light emits a red light to prompt a user to replace the reagent. In the second warning state, when the reagent exists, the indicator lights emit green lights, and the reagent is not replaced.
In an embodiment, as shown in fig. 1, the reagent detection device further includes a signal detection unit (not shown in the figure), where the signal detection unit is communicatively connected to the first optical coupler sensor 2 and the second optical coupler sensor 3, and is configured to read optical coupler signals of the first optical coupler sensor 2 and the second optical coupler sensor 3. Specifically, due to vibration of the external environment or the external operation, micro bubbles may be generated by the reagent, so that in order to avoid erroneous judgment caused by unstable optocoupler signals of the first optocoupler sensor 2 and the second optocoupler sensor 3, the signal detection unit can filter the optocoupler signals caused by the micro bubbles. In implementation, when the high-frequency current of the reagent sensed by the first optical coupler sensor 2 and the second optical coupler sensor 3 tends to be 1 value in one second, the signal detection unit can filter the optical coupler signal of the part, so that erroneous judgment is avoided.
The utility model also provides a cell analyzer, which comprises a control panel and the reagent detection device of the embodiment, wherein the control panel is in communication connection with the reagent detection device, so that the control panel can display whether the reagent exists or not, and the operations such as alarm elimination and the like are performed.
It can be understood that the cell analyzer is practical to the reagent detection device of this application for the accuracy that the bubble detected is higher, and then, improves the accuracy of judging whether reagent exists or not.
In some embodiments, the reagent detection device is installed inside the cell analyzer, is not interfered by external environment, and has lower maintenance cost.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The foregoing disclosure is illustrative of the present utility model and is not to be construed as limiting the scope of the utility model, which is defined by the appended claims.
Claims (10)
1. The reagent detection device is characterized by comprising a body part, a first optical coupler sensor and a second optical coupler sensor, wherein the body part is provided with a liquid channel, an inlet end and an outlet end which are communicated with the liquid channel, the first optical coupler sensor is arranged at the inlet end and is used for sensing reagent in the inlet end, and the second optical coupler sensor is arranged at the outlet end and is used for sensing reagent in the outlet end.
2. The reagent detecting apparatus according to claim 1, wherein the body portion includes a first portion and a second portion, and a connecting pipe connecting the first portion and the second portion, the inlet end is provided in the first portion, the outlet end is provided in the second portion, and an inner cavity of the connecting pipe forms the liquid passage.
3. The reagent detecting apparatus according to claim 2, wherein the first portion is formed with a first connector, the second portion is formed with a second connector, one end of the connecting pipe is inserted into the first connector, and the other end of the connecting pipe is inserted into the second connector.
4. The reagent testing device according to claim 2, wherein the first portion is further formed with a third connector, the second portion is further formed with a fourth connector, and the third connector and the fourth connector are each adapted to be connected to an external pipe.
5. The reagent detection device of claim 2, wherein the first optocoupler sensor is detachably connected to the first portion and the second optocoupler sensor is detachably connected to the second portion.
6. The reagent detecting apparatus according to claim 5, wherein the first portion is formed with a first insertion groove, the first optocoupler sensor is inserted into a groove wall of the first insertion groove, the second portion is formed with a second insertion groove, and the second optocoupler sensor is inserted into a groove wall of the second insertion groove.
7. The reagent detection device of claim 1, further comprising an alarm, the alarm having a first alarm state and a second alarm state;
in the first warning state, the first optical coupler sensor and the second optical coupler sensor sense that the reagent generates bubbles;
in the second warning state, the first optocoupler sensor senses that the reagent generates bubbles, the second optocoupler sensor senses that the reagent does not have bubbles, or the first optocoupler sensor and the second optocoupler sensor both sense that the reagent does not have bubbles.
8. The reagent detecting apparatus according to claim 7, wherein the alarm is a buzzer capable of making a sound and not making a sound to correspond to the first alarm state and the second alarm state.
9. The reagent detecting apparatus according to claim 1, further comprising a signal detecting unit communicatively connected to the first optical coupler sensor and the second optical coupler sensor and configured to read optical coupler signals of the first optical coupler sensor and the second optical coupler sensor.
10. A cell analyzer comprising a control panel and a reagent detection device according to any one of claims 1-9, wherein the control panel is in communication with the reagent detection device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320376429.5U CN219363643U (en) | 2023-02-24 | 2023-02-24 | Reagent detection device and cell analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320376429.5U CN219363643U (en) | 2023-02-24 | 2023-02-24 | Reagent detection device and cell analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219363643U true CN219363643U (en) | 2023-07-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320376429.5U Active CN219363643U (en) | 2023-02-24 | 2023-02-24 | Reagent detection device and cell analyzer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219363643U (en) |
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2023
- 2023-02-24 CN CN202320376429.5U patent/CN219363643U/en active Active
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