CN219354259U

CN219354259U - Mouse limb ischemia adaptation experiment fixing device

Info

Publication number: CN219354259U
Application number: CN202320505553.7U
Authority: CN
Inventors: 朱宏伟
Original assignee: Second Affiliated Hospital Of Baotou Medical College Of Inner Mongolia University Of Science And Technology Inner Mongolia Institute Of Digestive Diseases Inner Mongolia Institute Of Hypertension
Current assignee: Second Affiliated Hospital Of Baotou Medical College Of Inner Mongolia University Of Science And Technology Inner Mongolia Institute Of Digestive Diseases Inner Mongolia Institute Of Hypertension
Priority date: 2023-03-16
Filing date: 2023-03-16
Publication date: 2023-07-18
Anticipated expiration: 2033-03-16

Abstract

The utility model discloses an experimental fixing device for ischemia adaptation of a mouse limb, which relates to the technical field of ischemia adaptation equipment and comprises a fixing seat, wherein an inflatable bandage is fixedly connected to the middle position of the upper surface of the fixing seat, two ends of the inflatable bandage are connected through a magic tape, symmetrically arranged fixing plates are arranged on two sides of the upper surface of the fixing seat, an elastic mechanism is arranged between the fixing plates and the fixing seat, a ventilation control mechanism is arranged on the rear side of the inflatable bandage, and the elastic mechanism comprises round rods symmetrically and fixedly connected to the two sides of the fixing seat.

Description

Mouse limb ischemia adaptation experiment fixing device

Technical Field

The utility model relates to the technical field of ischemia adaptation equipment, in particular to a fixing device for an experiment of limb ischemia adaptation of a mouse.

Background

Remote ischemic adaptation refers to the process of repeatedly and transiently stimulating ischemia of an organ or tissue (such as limbs, etc.), and exciting endogenous anti-ischemic injury protection mechanism of an organism, so that other organs or tissues except the organ or tissue generate adaptation and tolerance to ischemic injury, thereby preventing or reducing the response degree of 'true' ischemic injury.

At present, the organ protection mechanism of remote ischemia adaptation is not clear, animal experiments become necessary means of exploration mechanisms, the existing remote ischemia adaptation experiments are all carried out by binding inflatable cuffs on the limbs of a mouse, then repeatedly inflating the cuffs by utilizing a ventilation control mechanism to carry out repeated ischemia stimulation on the limbs of the mouse, however, in the process of deflating the cuffs, the limbs of the mouse are loosened, and the limbs of the mouse are easy to fall off, so that the experiment is influenced, and therefore, the fixing device for the mouse limb ischemia adaptation experiments is provided.

Disclosure of Invention

The utility model aims to provide a fixing device for an experiment of ischemia adaptation of a limb of a mouse, which aims to solve the problems in the background technology.

In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a mouse limb ischemia adaptation experiment fixing device, includes the fixing base, fixing base upper surface intermediate position department fixedly connected with is aerifyd the bandage, it is connected through setting up the magic subsides to aerify the bandage both ends, fixing base upper surface is located and is aerifys the fixed plate that the bandage both sides were provided with the symmetry setting, just be provided with elastic mechanism between fixed plate and the fixing base, it is provided with ventilation control mechanism to aerify the bandage rear side.

Preferably, the elastic mechanism comprises round rods which are symmetrically and fixedly connected to two sides of the fixing base, the lower surfaces of the fixing plates are fixedly connected with vertical plates, the round rods penetrate through the vertical plates in a sliding mode, springs are sleeved on the outer surfaces of the round rods, one ends of the springs are fixedly connected with the fixing base, and the other ends of the springs are fixedly connected with the vertical plates.

Preferably, the ventilation control mechanism comprises a ventilation hose fixedly connected to the rear side of the inflatable bandage in a penetrating mode, and one end, far away from the inflatable bandage, of the ventilation hose is fixedly connected with the host machine.

Preferably, the lower surface fixedly connected with symmetry of riser sets up T type slider, T type groove of T type slider looks adaptation has been seted up to the fixing base upper surface, just T type slider slidable mounting is at T type inslot.

Preferably, clamping plates which are symmetrically arranged are connected to two sides of the fixing seat in a sliding mode, and the clamping plates are U-shaped.

Preferably, the right side of the inflatable bandage is fixedly connected with symmetrically arranged connecting plates, and the tops of the two connecting plates are rotationally connected with guide rods.

Compared with the prior art, the utility model has the beneficial effects that:

in the process of repeatedly inflating the inflatable bandage by utilizing the ventilation control mechanism, the elastic mechanism is matched with the fixing plates, when the inflatable bandage is compressed, the two fixing plates are mutually close to fix the limb of the mouse in the inflatable bandage, so that the limb of the mouse is prevented from sliding off from the inflatable bandage in the process of repeatedly inflating.

Drawings

FIG. 1 is a schematic view of the overall structure of the present utility model;

FIG. 2 is a schematic view of a part of the structure of the present utility model;

FIG. 3 is an enlarged view of the utility model at A in FIG. 2;

fig. 4 is an enlarged view of the present utility model at B in fig. 2.

In the figure: 1. a host; 2. a ventilation hose; 3. an inflatable strap; 4. a magic tape; 5. a fixing plate; 6. a fixing seat; 7. a clamping plate; 8. a riser; 9. a spring; 10. a round bar; 11. a T-shaped slider; 12. a T-shaped groove; 13. a connecting plate; 14. and a guide rod.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

Example 1

Referring to fig. 1-4 for illustrating an embodiment 1, a fixing device for a mouse limb ischemia adaptation experiment in the illustration includes a fixing base 6, an inflatable strap 3 is fixedly connected to a middle position of an upper surface of the fixing base 6, two ends of the inflatable strap 3 are connected through a hook and loop fastener 4, fixing plates 5 symmetrically arranged are arranged on two sides of the inflatable strap 3 on the upper surface of the fixing base 6, an elastic mechanism is arranged between the fixing plates 5 and the fixing base 6, and an ventilation control mechanism is arranged on a rear side of the inflatable strap 3.

Referring to fig. 1-3, the elastic mechanism includes round bars 10 symmetrically and fixedly connected to two sides of the fixed seat 6, the lower surface of the fixed plate 5 is fixedly connected with a riser 8, the round bars 10 slidably penetrate through the riser 8, a spring 9 is sleeved on the outer surface of the round bars 10, one end of the spring 9 is fixedly connected with the fixed seat 6, and the other end of the spring 9 is fixedly connected with the riser 8.

Referring to fig. 1-2, the ventilation control mechanism includes a ventilation hose 2 fixedly connected to the rear side of an inflatable strap 3, and a host 1 fixedly connected to one end of the ventilation hose 2 away from the inflatable strap 3.

Referring to fig. 1-3, a T-shaped slide block 11 is fixedly connected to the lower surface of the riser 8, a T-shaped groove 12 adapted to the T-shaped slide block 11 is provided on the upper surface of the fixing seat 6, and the T-shaped slide block 11 is slidably mounted inside the T-shaped groove 12.

In this embodiment, the mouse limb is placed in the inflatable bandage 3, then the inflatable bandage 3 is fixed by the magic tape 4, the inflation state of the inflatable bandage 3 can be controlled by the ventilation control mechanism, when the air is inflated into the inflatable bandage 3 through the ventilation hose 2, the inflatable bandage 3 is inflated, the fixing plates 5 move to two sides at this time, the springs 9 between the fixing seats 6 and the fixing plates 5 are in a compressed state, the inflatable bandage 3 is inflated to compress the mouse limb, the arterial blood supply of the limb is blocked, so that the mouse limb is in an ischemia state, after a few minutes, the ventilation control mechanism is used to draw out the air in the inflatable bandage 3, the inflatable bandage 3 is compressed at this time, the compressed springs 9 drive the fixing plates 5 at two sides to move to the middle, fix the mouse limb in the inflatable bandage 3, and prevent the mouse limb from sliding off the inflatable bandage 3 in the repeated inflation process.

In this embodiment, the main machine 1 in the ventilation control mechanism performs the procedure control of inflation and air extraction, so as to repeatedly inflate the inflatable bandage 3, and the inflation technology is the conventional technology and will not be described here again.

Example 2

Referring to fig. 1-2, two sides of the fixing seat 6 are slidably connected with symmetrically arranged clamping plates 7, and the clamping plates 7 are U-shaped.

In this embodiment, through setting up cardboard 7, bind the bandage 3 that will aerify before the mouse limbs, can remove fixed plate 5 to the one side of keeping away from the bandage 3 that aerifing to utilize cardboard 7 to detain at riser 8 surface, avoid fixed plate 5 and riser 8 to cause the hindrance at the in-process of tying up the bandage 3 that aerifing.

Example 3

Referring to fig. 1-4, the right side of the inflatable bandage 3 is fixedly connected with symmetrically arranged connecting plates 13, and the tops of the two connecting plates 13 are rotatably connected with a guide rod 14.

In this embodiment, the inflatable bandage 3 passes through the guide rod 14, so that two ends of the inflatable bandage 3 are aligned when being adhered, and the inflatable bandage is more firmly adhered.

It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a mouse limb ischemia adaptation experiment fixing device, includes fixing base (6), its characterized in that, fixing base (6) upper surface intermediate position department fixedly connected with is aerifyd bandage (3), it is connected through setting up magic subsides (4) to aerify bandage (3) both ends, fixing base (6) upper surface is located and is aerifyd bandage (3) both sides and be provided with fixed plate (5) that the symmetry set up, just be provided with elastic mechanism between fixed plate (5) and fixing base (6), it is provided with ventilation control mechanism to aerify bandage (3) rear side.

2. The mouse limb ischemia adaptation experiment fixing device according to claim 1, wherein: the elastic mechanism comprises round rods (10) which are symmetrically and fixedly connected to two sides of the fixed seat (6), vertical plates (8) are fixedly connected to the lower surface of the fixed plate (5), the round rods (10) penetrate through the vertical plates (8) in a sliding mode, springs (9) are sleeved on the outer surfaces of the round rods (10), one ends of the springs (9) are fixedly connected with the fixed seat (6), and the other ends of the springs (9) are fixedly connected with the vertical plates (8).

3. The mouse limb ischemia adaptation experiment fixing device according to claim 1, wherein: the ventilation control mechanism comprises a ventilation hose (2) fixedly connected to the rear side of the inflatable bandage (3) in a penetrating mode, and one end, far away from the inflatable bandage (3), of the ventilation hose (2) is fixedly connected with a host machine (1).

4. The mouse limb ischemia adaptation experiment fixing device according to claim 2, wherein: t type slider (11) that the lower fixed surface of riser (8) set up symmetrically are connected with, T type groove (12) of T type slider (11) looks adaptation have been seted up to fixing base (6) upper surface, just T type slider (11) slidable mounting is inside T type groove (12).

5. The mouse limb ischemia adaptation experiment fixing device according to claim 1, wherein: clamping plates (7) which are symmetrically arranged are connected to two sides of the fixing seat (6) in a sliding mode, and the clamping plates (7) are U-shaped.

6. The mouse limb ischemia adaptation experiment fixing device according to claim 1, wherein: the right side of the inflatable bandage (3) is fixedly connected with symmetrically arranged connecting plates (13), and the tops of the two connecting plates (13) are rotatably connected with guide rods (14).