CN219323446U - Endometrial sampler - Google Patents

Abstract

The utility model discloses an endometrium sampler, which comprises an elongated tubular outer sleeve and an inner sleeve, wherein the outer surface of the inner sleeve is movably matched with the inner surface of the outer sleeve and is used for extending and retracting the inner sleeve from the outer sleeve; the other end of the inner sleeve is provided with a spike; openings penetrating through the side wall of the inner sleeve are formed at the rear parts of the two sides of the spike; the top end of the outer sleeve is provided with an elastic plastic film. The endometrial sampler can avoid the pollution of the lower genital tract flora to the endometrial flora, and the detection result of the endometrial flora is more accurate.

Description

Endometrial sampler

Technical Field

The utility model relates to the technical field of medical equipment, in particular to an endometrium sampler.

Background

With the widespread use of high throughput sequencing technology, the concept of sterility of the uterine cavity has been negated, the symbiotic flora of the uterine cavity may play a role in protecting and promoting development of the endometrium, while abnormal flora may lead to inflammation and impaired endometrial function. Studies have reported that endometrial microbiota of in vitro fertilization-embryo transfer (in-vitro fertilization, IVF) patients can predict implantation rate and pregnancy rate, and that endometrial microbiota is a dominant lactobacillus patient with a higher embryo implantation success rate.

Since the sampling of the endometrial flora is performed through vagina and cervix uteri, the current sampler can not well avoid the pollution of the lower genital tract flora, so the research result of the endometrial flora is frequently questioned. Currently, the commonly used endometrial flora samplers mainly comprise two main types, one type is an endometrial sampler with an outer sleeve protection, such as an embryo transfer catheter (shown in figure 1), an endometrial cell collector (SPA-I), an endometrial suction tube and the like, and the other type is an endometrial sampler without an outer sleeve protection, such as an artificial insemination tube, which is used less.

The common problem of endometrium samplers protected by outer sleeves is that the top end design of the sampler cannot well avoid the pollution of the lower genital tract flora, and the top end of the sampler is either open design, such as embryo transfer catheter and endometrium suction tube, cervical mucus can directly enter the inner tube to pollute the endometrium tissue specimen; or the device is designed with a ball, such as an endometrial cell collector (SPA-I), and the ball at the top end of the device can enter the uterine cavity during sampling, so that a small amount of cervical mucus cannot be carried into the uterine cavity.

The most commonly used sampler for detecting the endometrial bacteria group in clinic at present is an endometrial suction tube, besides the open top design, in the operation process, an outer sleeve needs to pass through a cervix to reach the deep part of a uterine cavity, besides the possible pollution of the top, a great amount of cervical mucus is carried by the outer sleeve to enter the uterine cavity, and the bacterial load is gradually reduced from a vagina to the cervix to the uterine cavity, so that the endometrial bacteria group has extremely low content compared with the lower genital bacteria group, and even if the lower genital bacteria group is brought into the uterine cavity, the detection result of the endometrial bacteria group is possibly influenced.

For example, the embryo transplantation sleeve shown in fig. 1 comprises an inner sleeve and an outer sleeve which are independent from each other, and when sampling is performed, the outer sleeve is firstly placed into a uterine cavity, then the inner sleeve enters the uterine cavity along the inner cavity gap of the outer sleeve, and uterine cavity liquid is sucked for sampling. After the sampling is finished, the inner sleeve is retracted into the outer sleeve, and the genital tract is withdrawn together. Disadvantages: 1. the embryo transfer catheter has higher cost; 2. the inner tube is soft and slim, is not suitable for sampling endometrial tissues, and can only absorb uterine cavity liquid to detect uterine cavity flora; 3. the top end of the outer tube is open, and is easy to be polluted by cervical mucus.

Disclosure of Invention

In order to solve the technical problems that in the prior art, when modes such as an embryo transfer sleeve are utilized, the manufacturing cost of the embryo transfer catheter is high, the inner tube is soft and slim and is not suitable for sampling endometrial tissues, only uterine cavity liquid can be sucked to detect uterine cavity flora, the top end of the outer tube is open, cervical mucus pollution is easy to occur, and the like, the utility model provides an endometrial sampler, which can well avoid pollution of lower genital tract flora to endometrial flora and enable the detection result of the endometrial flora to be more accurate.

In order to achieve the object, the utility model adopts the following technical scheme.

An endometrial sampler comprises an elongated tubular outer sleeve and an inner sleeve, wherein the outer surface of the inner sleeve is movably matched with the inner surface of the outer sleeve, the inner sleeve is used for extending and retracting from the outer sleeve, an inner core is arranged in the inner sleeve, the rear end of the inner core extends from one end of the inner sleeve and is connected to a handle; the other end of the inner sleeve is provided with a spike; openings penetrating through the side wall of the inner sleeve are formed at the rear parts of the two sides of the spike; the top end of the outer sleeve is provided with an elastic plastic film.

The endometrium sampler comprises the inner sleeve and the outer sleeve, the top end of the outer sleeve is sealed by the elastic plastic film, cervical mucus is prevented from entering the inner tube, pollution can be avoided, and the accuracy of a detection result is improved. In addition, in the utility model, the tip of the inner sleeve is provided with a needle tip design, for example, about 1mm, so that the elastic plastic film at the top end of the outer sleeve is punctured before the endometrial tissue sampling, thereby being convenient to operate. The plastic film at the top end of the outer sleeve has elasticity, and can automatically retract to the side surface of the top end of the outer sleeve after being punctured, so that the inner sleeve entering the uterine cavity is prevented from being touched, and the top end of the inner sleeve is prevented from being polluted by cervical mucus.

In the endometrial sampler, the outer part of the outer sleeve is also provided with the fixer which can move along the axial direction of the outer sleeve and has a plurality of scales distributed along the axial direction on the side peripheral surface of the outer sleeve near the top end, and the scales are used for setting the position of the fixer.

In the endometrial sampler of the utility model, the side peripheral surface of one side of the inner sleeve, which is close to the handle, is provided with a plurality of scales which are axially distributed and are used for marking the depth of the inner sleeve entering the outer sleeve.

The top end of the outer sleeve and the tail end of the inner sleeve in the endometrial sampler are provided with scale marks, so that the depth of the sampler entering the uterine cavity can be judged, and whether the inner sleeve completely retreats to the inner part of the outer sleeve can be judged.

In the endometrial sampler of the utility model, the outer part of the outer sleeve is also provided with a first connector 51 and a second connector 52 which are respectively provided with movable annular structures at different axial positions, and the first connector 51 and the second connector 52 are matched with the outer peripheral surface of the outer sleeve in a close manner and are used for keeping the relative fixation between the outer sleeve and the inner sleeve after the inner sleeve penetrates into the outer sleeve to a preset position.

The utility model has the advantages that the sampler comprises an inner sleeve and an outer sleeve, and the top end of the outer sleeve of the sampler is sealed by an elastic plastic film, so that the pollution caused by cervical mucus in the process of endometrium sampling can be avoided to the greatest extent. The top end of the outer sleeve and the tail end of the inner sleeve are provided with scale marks, so that the depth of the sampler entering the uterine cavity can be judged, and whether the inner sleeve completely retreats to the inside of the outer sleeve or not can be judged. The endometrial tissue obtained by the sampling of the utility model not only can be used for detecting endometrial flora, but also can be used for detecting endometrial receptivity, endometrial pathology and the like, and has wide application prospect.

Drawings

FIG. 1 is a schematic view of an embryo transfer catheter according to the prior art.

Fig. 2 is a schematic structural view of an endometrial sampler according to an embodiment of the present utility model.

Detailed Description

The present utility model will be described in detail with reference to the accompanying drawings.

Detailed exemplary embodiments are disclosed below. However, specific structural and functional details disclosed herein are merely for purposes of describing example embodiments.

It should be understood, however, that the utility model is not limited to the particular exemplary embodiments disclosed, but is to cover all modifications, equivalents, and alternatives falling within the scope of the disclosure. Like reference numerals refer to like elements throughout the description of the drawings.

Referring to the drawings, the structures, proportions, sizes, etc. shown in the drawings are shown only in connection with the disclosure of the present utility model, and are not intended to limit the scope of the utility model, which is defined by the claims, so that any structural modifications, proportional changes, or adjustments of sizes may be made without affecting the efficacy of the utility model or achieving the purpose, and are therefore within the scope of the disclosure. In addition, the positional limitation terms recited in the present specification are used merely for convenience of description, and are not intended to limit the scope of the utility model, in which the relative changes or modifications are regarded as the scope of the utility model without any substantial modification to the technical content.

It should also be understood that the term "and/or" as used herein includes any and all combinations of one or more of the associated listed items. It will also be understood that when a component or element is referred to as being "connected" or "coupled" to another component or element, it can be directly connected or coupled to the other component or element or intervening components or elements may also be present. Moreover, other words used to describe the relationship between components or units should be interpreted in the same manner (e.g., "between" versus "directly between," "adjacent" versus "directly adjacent," etc.).

Fig. 2 is a schematic view showing a part of the structure of an endometrial sampler according to an embodiment of the utility model. As shown in the drawings, the present embodiment comprises an endometrium sampler comprising an elongated tubular outer sleeve 10 and an inner sleeve 20, wherein the outer surface of the inner sleeve 20 is movably matched with the inner surface of the outer sleeve 10 for extending and retracting the inner sleeve 20 from the outer sleeve 10, the inner sleeve 20 is internally provided with an inner core 23, and the rear end of the inner core 23 extends from one end, namely the rear end, of the inner sleeve 20 and is connected to a handle 25; the other end, the front end, of the inner sleeve 20 is provided with a spike 21; openings 22 penetrating through the side wall of the inner sleeve 20 are formed behind the two sides of the spike 21; the top end of the outer sleeve 10 is provided with an elastic plastic film 11.

In the description of the present utility model, if not specified, the tip and the front end refer to the end which goes deep into the sampling position, and have the elastic plastic film 11, the spike 21, and the like; the rear end, distal end, refers to the end proximal to the handle 25.

The endometrium sampler comprises the inner sleeve 10 and the outer sleeve 20, the top end of the outer sleeve 10 is sealed by the elastic plastic film 11, cervical mucus is prevented from entering the inner sleeve 20, so that pollution can be avoided, and the accuracy of a detection result is improved. In addition, in the utility model, the tip end of the inner sleeve 20 is provided with a spike 21, for example, about 1mm, which is used for puncturing the elastic plastic film 11 at the tip end of the outer sleeve 10 before the endometrial tissue is sampled, so that the operation is convenient. The elastic plastic film 11 at the top end of the outer sleeve 10 has elasticity, and can automatically retract to the side surface of the top end of the outer sleeve 10 after being punctured, so as to avoid touching the inner sleeve 20 entering the uterine cavity, and further avoid the pollution of the top end of the inner sleeve 20 by cervical mucus.

In the endometrial sampler of the utility model, the outer sleeve 10 is also provided with the fixer 30 which can move along the axial direction of the outer sleeve 10 and has a plurality of scales distributed along the axial direction on the side peripheral surface of the outer sleeve near the top end, and the positions of the fixer 30 are set. Thus, after the outer cannula 10 is inserted into the uterine cavity, the holder 30 is set to fix the positions of the outer cannula 10 and the inner cannula 20.

In the endometrial sampler of the present utility model, the side circumferential surface of the inner sleeve 20 near the handle 25 side is provided with a plurality of graduations axially distributed for marking the depth of the inner sleeve 20 into the outer sleeve 10.

The top end of the outer sleeve 10 and the tail end of the inner sleeve 20 in the endometrial sampler are provided with scale marks, so that the depth of the endometrial sampler entering the uterine cavity and whether the inner sleeve 20 is completely retracted into the outer sleeve 10 can be judged.

In the endometrial sampler of the present utility model, the outer sleeve 10 is further provided with a first connector 51 and a second connector 52 having movable ring structures at different axial positions outside thereof, respectively, the first connector 51 and the second connector 52 being closely matched with the outer circumferential surface of the outer sleeve 10 for maintaining the relative fixation between the outer sleeve 10 and the inner sleeve 20 by pressing the outer sleeve 10 from outside after the inner sleeve 20 is deep into the outer sleeve 10 to a predetermined position, applying a frictional force between the outer sleeve 10 and the inner sleeve 20.

The utility model has the advantages that the sampler comprises an inner sleeve and an outer sleeve, and the top end of the outer sleeve 10 of the sampler is sealed by an elastic plastic film 11, so that the pollution caused by cervical mucus in the process of endometrium sampling can be avoided to the greatest extent. The top end of the outer sleeve 10 and the tail end of the inner sleeve 20 are provided with scale marks, which are helpful for judging the depth of the endometrium sampler entering the uterine cavity and whether the inner sleeve 20 is completely retracted into the outer sleeve 10. The endometrial tissue obtained by the sampling of the utility model not only can be used for detecting endometrial flora, but also can be used for detecting endometrial receptivity, endometrial pathology and the like, and has wide application prospect.

Specifically, in the embodiment of the present utility model, the outer sleeve 10 is a transparent tube, the top end of the outer sleeve 10 is closed by an elastic plastic film 11, the outer surface of the outer sleeve 10 with the length of 4 cm from the top end of the outer sleeve 10 is provided with graduation marks, each 1 cm is provided with 1 graduation mark, and 1 movable fixer is arranged after the outer sleeve 10 enters the uterine cavity to fix the position of the endometrium sampler. The outer sleeve 10 has a connector 1 at its distal end for connecting the inner and outer sleeves. The inner sleeve 20 is also a transparent tube, the top end of the inner sleeve is provided with a spike 21 with the length of 1 millimeter, the elastic plastic film 11 at the top end of the outer sleeve 10 is punctured before sampling, the elastic plastic film 11 has elasticity, and the inner sleeve can automatically retract to the side surface of the top end of the outer sleeve 10 after being punctured, so that the inner sleeve 20 entering the uterine cavity is prevented from touching, and the top end of the inner sleeve 20 is prevented from being polluted by cervical mucus. The side of the top end of the inner sleeve 20 is provided with an opening for sucking endometrial tissues, and the tail end of the inner sleeve 20 is provided with scales for measuring the depth of the inner sleeve 20 entering the uterine cavity. The inner sleeve 20 is internally provided with an inner core 23, the front end of the inner core 23 is of a piston structure, the tail end of the inner core is provided with a handle 25, and negative pressure can be generated by pulling the handle 25, so that endometrial tissues are sucked into the inner sleeve 20.

More specifically, in operation of the endometrial sampler according to embodiments of the present utility model, the endometrial sampler is placed into the uterine cavity transvaginally and access is stopped at a predetermined position after passing through the endocervical opening (the graduations on the outer surface of the front end of the outer sleeve 10 help to assist in determining whether the endometrial sampler has been accessed and the depth of access). Pushing the inner sleeve 20, puncturing the elastic plastic film 11 at the top end of the outer sleeve 10, allowing the inner sleeve 20 to enter the uterine cavity to reach the uterine bottom (the scale at the tail end of the inner sleeve helps to judge the depth of the endometrium sampler entering the uterine cavity). The handle 25 at the end of the inner core 23 is then pulled outwards to generate negative pressure in the inner sleeve 20, so that endometrial tissue enters the inner sleeve 20 through the opening 22 at the top end of the inner sleeve 20, and sampling is completed. When the inner cannula 20 is retracted into the interior of the outer cannula 10 (the graduations at the end of the inner cannula help to assist in determining whether the sampler has completely entered the interior of the inner cannula), the genital tract is withdrawn.

While the foregoing description illustrates and describes the preferred embodiments of the present utility model, it is to be understood that the utility model is not limited to the form disclosed herein, but is not to be construed as limited to other embodiments, but is capable of numerous other combinations, modifications and environments and is capable of changes or modifications within the scope of the inventive concept as described herein, either as a result of the foregoing teachings or as a result of the knowledge or skills of the relevant art. And that modifications and variations which do not depart from the spirit and scope of the utility model are intended to be within the scope of the appended claims.

Claims (4)

1. An endometrial sampler comprising an elongated tubular outer sleeve and an inner sleeve, the outer surface of the inner sleeve being movably matched to the inner surface of the outer sleeve for extension and retraction of the inner sleeve from the outer sleeve, characterized in that the inner sleeve has an inner core inside, the rear end of the inner core extending from one end of the inner sleeve, connected to a handle; the other end of the inner sleeve is provided with a spike; openings penetrating through the side wall of the inner sleeve are formed at the rear parts of the two sides of the spike; the top end of the outer sleeve is provided with an elastic plastic film.

2. The endometrial sampler of claim 1, wherein the outer sleeve further comprises a retainer of annular configuration axially movable along the outer sleeve, and wherein the outer sleeve has a plurality of axially distributed graduations on a lateral peripheral surface thereof adjacent the tip for setting the position of the retainer.

3. The endometrial sampler of claim 1, wherein the side circumferential surface of the inner sleeve proximal to the handle has a plurality of axially distributed graduations for marking the depth of the inner sleeve into the outer sleeve.

4. The endometrial sampler of claim 1, wherein the outer sleeve has first and second connectors of movable annular structures at different axial positions on the outer sleeve, respectively, the first and second connectors being adapted to mate with the outer circumference of the outer sleeve in a closely abutting manner for maintaining the relative fixation between the outer sleeve and the inner sleeve after the inner sleeve has been advanced into the outer sleeve to a predetermined position.

Images