CN219266314U - Sample analyzer and reagent storage device - Google Patents

Abstract

The utility model relates to a sample analyzer and a reagent storage device, wherein the reagent storage device comprises a reagent bin, a rotating piece, a driving piece and a driving module; the reagent bin comprises at least two reagent storage units; the driving piece comprises magnetic materials and/or nucleophilic materials, is arranged on the rotating piece, is arranged at intervals with the rotating axis of the rotating piece, and corresponds to the connecting line of the reagent storage unit along with the moving path of the rotating piece so as to provide a dynamically changing magnetic field for the stirrer in the reagent bottle; the driving module is connected with the rotating piece to drive the rotating piece to rotate around the rotating axis. According to the utility model, the driving module can drive the rotating member to rotate, and the driving member provides a dynamic magnetic field, and the dynamic magnetic field can drive the stirrer to move in the reagent bottle, so that reagents in the reagent bottle can be stirred and evenly mixed by the stirrer, the precipitation phenomenon of the reagents is avoided, the manual operation is not required in the stirring process, and a user obtains good use experience.

Description

Sample analyzer and reagent storage device

Technical Field

The utility model relates to the field of medical instruments, in particular to a sample analyzer and a reagent storage device.

Background

In analyzing a sample using a sample analyzer such as a coagulation analyzer, it is often necessary to add various reagents to the sample. For convenient operation, the reagent is usually stored in the sample analyzer, and due to the preparation process and component arrangement of different reagents, the reagent stored in the sample analyzer for a long time is easy to precipitate under the standing storage condition, such as clot, floccule, insoluble matters and the like, thereby causing reagent failure. The reuse of reagents that have already precipitated can affect analytical test data measured by the sample analyzer. In order to solve the problem that the reagent is easy to precipitate under the standing storage condition, the reagent can be mixed by manually shaking the reagent or stirring the reagent by a reagent needle, however, the reagent mixing operation is complex by the methods, and the experience is poor.

Disclosure of Invention

The utility model aims to provide an improved sample analyzer and a reagent storage device.

The technical scheme adopted for solving the technical problems is as follows: constructing a reagent storage device, comprising a reagent bin, a rotating piece, at least one driving piece and a driving module; the reagent bin comprises at least two reagent storage units; the at least one driving piece comprises magnetic materials and/or nucleophilic materials, is arranged on the rotating piece, is arranged at intervals with the rotating axis of the rotating piece, and corresponds to the connecting line of the at least two reagent storage units along the moving path of the rotating piece so as to provide a dynamically changing magnetic field for the stirrer in the reagent bottle; the driving module is connected with the rotating piece to drive the rotating piece to rotate around the rotating axis.

In some embodiments, the rotating member is rotatably disposed below the reagent cartridge, and its axis of rotation is parallel to the plane of the reagent cartridge.

In some embodiments, the at least one driver comprises a magnetic material and the magnetic poles are disposed outwardly.

In some embodiments, the at least one drive member comprises at least two drive members, the at least two drive members being centrally symmetrically distributed with respect to the axis of rotation.

In some embodiments, the rotating member is disc-shaped with an axis coincident with or parallel to the axis of rotation.

In some embodiments, the rotating member has a disk shape, and the at least one driving member is disposed at an edge of the rotating member, and a magnetic axis thereof is disposed along a radial direction of the rotating member.

In some embodiments, the at least one driver is configured to: when the at least one driving member rotates with the rotating member, a plane formed by a magnetic axis of the at least one driving member passes through the at least two reagent storage units.

In some embodiments, the line connecting the at least two reagent storage units is linear and perpendicular to the axis of rotation.

In some embodiments, the at least two reagent storage units comprise at least three reagent storage units, and the lines of the at least three reagent storage units are in a straight line and perpendicular to the rotation axis.

A sample analyzer is also constructed comprising the reagent storage device of any of the above, and further comprising a housing in which the reagent storage device is mounted.

The implementation of the utility model has at least the following beneficial effects: according to the utility model, the driving module can drive the rotating member to rotate, and the driving member provides a dynamic magnetic field, and the dynamic magnetic field can drive the stirrer to move in the reagent bottle, so that reagents in the reagent bottle can be stirred and evenly mixed by the stirrer, the precipitation phenomenon of the reagents is avoided, the manual operation is not required in the stirring process, and a user obtains good use experience.

Drawings

The utility model will be further described with reference to the accompanying drawings and examples, in which:

FIG. 1 is a schematic perspective view of a sample analyzer according to some embodiments of the utility model;

FIG. 2 is a partial cross-sectional view of a reagent storage device according to some embodiments of the present utility model;

FIG. 3 is a top view of the reagent storage device of FIG. 2;

FIG. 4 is a front cross-sectional view of the reagent storage device of FIG. 2;

FIG. 5 is a front cross-sectional view of the reagent storage device of FIG. 2 in another state;

FIG. 6 is a front cross-sectional view of the reagent storage device of FIG. 2 in a third state;

FIG. 7 is a front cross-sectional view of the reagent storage device of FIG. 2 in a fourth state.

Detailed Description

For a clearer understanding of technical features, objects and effects of the present utility model, a detailed description of embodiments of the present utility model will be made with reference to the accompanying drawings. In the following description, it should be understood that the directions or positional relationships indicated by "front", "rear", "upper", "lower", "left", "right", "longitudinal", "transverse", "vertical", "horizontal", "top", "bottom", "inner", "outer", "head", "tail", etc. are configured and operated in specific directions based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present utility model, and do not indicate that the apparatus or element to be referred to must have specific directions, and thus should not be construed as limiting the present utility model.

It should also be noted that unless explicitly stated or limited otherwise, terms such as "mounted," "connected," "secured," "disposed," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. When an element is referred to as being "on" or "under" another element, it can be "directly" or "indirectly" on the other element or one or more intervening elements may also be present. The terms "first," "second," "third," and the like are used merely for convenience in describing the present utility model and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated, whereby features defining "first," "second," "third," etc. may explicitly or implicitly include one or more such features. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the following description, for purposes of explanation and not limitation, specific details are set forth such as the particular system architecture, techniques, etc., in order to provide a thorough understanding of the embodiments of the present utility model. It will be apparent, however, to one skilled in the art that the present utility model may be practiced in other embodiments that depart from these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present utility model with unnecessary detail.

Fig. 1 illustrates a sample analyzer 100 in some embodiments of the utility model, the sample analyzer 100 may be a coagulation analyzer for performing coagulation and anticoagulation, fibrinolysis, and antifibrinolytic functions on a patient's blood. It will be appreciated that the sample analyzer 100 is not limited to a coagulation analyzer, and in some embodiments may be other sample analyzers such as a blood cell analyzer.

The sample analyzer 100 in some embodiments includes a reagent storage device 1 and a case 2, where the reagent storage device 1 is installed in the case 2, and can be used to accommodate a reagent that needs to be added in a sample when the sample analyzer 100 analyzes, and can perform a mixing operation on the reagent that needs to be mixed uniformly, so as to avoid precipitation of the reagent, and thus avoid the precipitation from affecting the accuracy of the sample analyzer 100 in analyzing sample data.

As shown in fig. 2, the reagent storage device 1 may in some embodiments comprise a reagent cartridge 10, a rotating member 20, a pair of driving members 30 and a driving module 40. The reagent cartridge 10 is in some embodiments flat plate-like and horizontally disposed, and the reagent cartridge 10 is located above the rotating member 20, which can be used to house a plurality of reagent bottles 200. The rotary member 20 is connected to the drive module 40 and is located below the reagent cartridge 10, which is rotatable under the drive of the drive module 40, and in some embodiments the axis of rotation a of the rotary member 20 is parallel to the plane in which the reagent cartridge 10 lies. The pair of driving members 30 are installed on the rotating member 20 in a central symmetry manner and are spaced from the rotation axis a of the rotating member 20, and can provide a magnetic field with variable intensity and direction for the reagent cartridge 10 under the driving of the rotation of the rotating member 20 so as to drive the movement of the stirrer 300 placed in the reagent bottle 200 to be mixed in the reagent cartridge 10, so as to mix the reagents stored in the reagent bottle 200. The driving module 40 is installed in the chassis 2, and its power output end is connected to the rotating member 20, and is used for driving the rotating member 20 to rotate around its rotation axis a, so as to drive the driving member 30 to rotate. It will be appreciated that the driver 30 may be configured as a driver with magnetic material or as a component with magnetic material, and that when the driver is configured as a component with magnetic material but not with magnetic material, the components of the cartridge 10 for mixing are configured as components with magnetic material. The number of driving members 30 is not limited to two, and one or more may be applicable.

In some embodiments, these reagent bottles 200 are placed obliquely at an angle on the reagent cartridge 10, which can be used to hold reagents that need to be tested. The stirrer 300 driven by the magnetic field is arranged in the reagent bottle 200 of which part is required to be uniformly mixed, and the density of the stirrer 300 is larger than that of the reagent required to be stirred, so that the stirrer can be positioned at the bottom of the reagent bottle 200, and the stirring is convenient. Specifically, the stirrer 300 is movable in the reagent bottle 200 by the magnetic field of the driving member 30, thereby stirring the reagent contained in the reagent bottle 200 and preventing the reagent from precipitating. Since the reagent bottle 200 is placed at an inclined angle when placed, the stirrer 300 can be kept at the lowest point of the reagent bottle 200 under the condition of no magnetic field or insufficient magnetic field strength, thereby preventing the stirrer 300 from affecting the reagent needle to suck the reagent when the reagent in the reagent bottle 200 is sucked in the analysis process.

In some embodiments, the stirrer 300 is made of a material that can induce magnetism, such as a material containing iron, cobalt, nickel, etc., so that it can move under the driving of the magnetic field of the driving member 30. It will be appreciated that where the driver 30 is provided as a magnetically philic material rather than a magnetic material, the interior of the stirrer 300 should be provided as a magnetic material, such as a permanent magnet or the like. In addition, the outside of the stirrer 300 is a coating layer, and the coating layer can be used for preventing the stirrer 300 from reacting with the reagent, so as to avoid affecting the color or chemical property of the reagent. In some embodiments, the coating may be a teflon material. It will be appreciated that the coating may also be a wear resistant material other than teflon that does not react with the reagent.

As shown in fig. 4-7, reagent bottles 200 may in some embodiments include a first type of reagent bottles that require mixing and a second type of reagent bottles that do not require mixing, which in some embodiments may include adjacent and evenly spaced apart first 201, second 202, and third 203 reagent bottles that are in a straight line. The stirrer 300 may include a first stirrer 301, a second stirrer 302 and a third stirrer 303 in some embodiments, and the first stirrer 301, the second stirrer 302 and the third stirrer 303 are respectively accommodated in the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203 for stirring the reagents in the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203. It will be appreciated that the number of reagent bottles of the first type is not limited to three, and fewer or more than three may be suitable.

As shown in fig. 2, the reagent cartridge 10 may include a reagent rack 11 and a plurality of reagent storage units 12 in some embodiments. The reagent storage units 12 are uniformly and alternately arranged on the reagent rack 11 in the horizontal direction, and each reagent storage unit 12 is inclined at a certain angle. The reagent storage units 12 are configured to store a plurality of reagent bottles 200, respectively, so that the reagent bottles 200 can be uniformly and obliquely placed on the reagent chamber 10.

The reagent storage units 12 may in some embodiments comprise a first type of reagent storage unit for housing a first type of reagent bottle and a second type of reagent storage unit for housing a second type of reagent bottle, the first type of reagent storage unit defining a mixing station 13, and may comprise three reagent storage units for housing the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203, respectively. The three reagent storage units are connected in a straight line and perpendicular to the rotation axis a of the rotary member 20. Further, the three reagent storage units are wired in a plane in which the driving member 30 rotates.

The rotary member 20 is in some embodiments disc-shaped, the axis of rotation a of the rotary member 20 being arranged horizontally, the central axis of the rotary member 20 (the axis on which the geometric center is located) being parallel to the axis of rotation a thereof. In some embodiments, the central axis of the rotary member 20 coincides with its axis of rotation a. The plane in which the rotating member 20 rotates is vertically arranged, perpendicular to the reagent cartridge 10, and perpendicular to the power output shaft of the driving module 40, and in the vertical direction, the rotating member 20 is located below the plurality of reagent storage units 12. It will be appreciated that the rotating member 20 may also be provided in some implementations as a rod or other shape. The plane in which the rotating member 20 rotates can be set at a certain angle, so that the setting mode of moving the stirring rod and realizing the stirring effect is applicable.

As shown in fig. 4 to 7, the driving member 30 may be made of a permanent magnet material in some embodiments, and may be mounted on two opposite sides of the rotating member 20, and the magnetic poles (south pole or north pole) thereof are disposed outwards, so that, during operation, the magnetic poles may face the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203, and thus, the stirrer 300 in the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203 may be driven by using a stronger magnetic field, thereby obtaining a better stirring effect.

In some embodiments, the plane in which the drive member 30 rotates is a vertical plane, and the first reagent bottle 201, the second reagent bottle 202, and the third reagent bottle 203 are adjacent to the vertical plane so that they can be located in a strong magnetic field. The moving path of the driving member 30 corresponds to the connection line of the plurality of reagent storage units 12, and each driving member 30 can sequentially drive the stirrers 300 in the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203 when moving, so that the utilization efficiency of the generated magnetic field is higher.

It can be understood that the driving member 30 is not limited to a permanent magnet, and may be configured by an electromagnet, and when the electromagnet is used as the driving member 30, the excitation of the magnetic field can be controlled by whether the electromagnet is electrified, the intensity of the magnetic field can be controlled by the magnitude of the current or the voltage, so as to obtain different magnetic field intensities, and the stirrer 300 is driven by the magnetic force with different magnitudes, so that more reagents with different viscosities can be adapted, and the application range of the reagent storage device 1 is expanded.

The driving member 30 may include a first magnetic element 31 mounted on an edge of the rotating member 20 and a second magnetic element 32 disposed at the other end of the rotating member 20 in the diameter direction on a plane of the rotating member 20 with respect to the first magnetic element 31, in some embodiments, the first magnetic element 31 and the second magnetic element 32 are symmetrically distributed with respect to a rotation axis a of the rotating member 20, and the rotation axis a of the rotating member 20 is a symmetry center.

The magnetic axes B of the first magnetic element 31 and the second magnetic element 32 are arranged in the radial direction of the rotating member 20, and in some embodiments, perpendicular to and intersecting the rotational axis a of the rotating member 20, so that the magnetic field strength is maximized when passing near the reagent cartridge 10 during rotation. The plane where the magnetic axis B is located passes through the reagent storage unit 12 where the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203 are placed when the magnetic axis B rotates, so that the magnetic field intensity where the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203 are located can be ensured to be strongest, and a better stirring effect can be obtained.

In some embodiments, the first magnetic element 31 and the second magnetic element 32 are small magnets mounted on the rotating member 20. When the connection line of the first magnetic element 31 and the second magnetic element 32 is in a horizontal state, any one of the first magnetic element 31 and the second magnetic element 32 is located directly below the first reagent bottle 201 or the third reagent bottle 203; when either one of the first magnetic element 31 and the second magnetic element 32 is in the upper position, it is located between the first reagent bottle 201 or the third reagent bottle 203 and the second reagent bottle 202; when either one of the first magnetic element 31 and the second magnetic element 32 is in the highest position, it is located directly under the second reagent bottle 202.

As shown in fig. 2 and 3, the drive module 40 may include a motor 41 and a motor bracket 42 in some embodiments. The motor 41 can be mounted on the motor bracket 42, the rotation shaft of the motor 41 is horizontally arranged and can be used for providing power for the movement of the driving piece 30, and the rotation direction can be any selected clockwise or anticlockwise; preferably, the rotation direction of the motor 41 in the present embodiment is counterclockwise. The motor support 42 is fixedly arranged, the motor 41 is arranged in the middle of the motor support 42, and the top of the motor support 42 is connected to the bottom of the reagent bin 10. The reagent cartridge 10 may be disposed corresponding to the driving module 40 through the motor bracket 42, and maintain a positional relationship of the reagent cartridge 10 above the driving module 40.

Because the rotation shaft of the motor 41 is horizontally disposed, the rotating member 20 can rotate on the vertical plane, so as to drive the stirrer 300 to move in the first reagent bottle 201, the second reagent bottle 202 and the third reagent bottle 203. In some embodiments, the rotating member 20 defines a mixing position 13 corresponding to the position of the reagent chamber 10, where the first reagent bottle 201, the second reagent bottle 202, and the third reagent bottle 203 can mix the reagent contained in the reagent bottle 200 under the rotation of the rotating member 20.

When the motor 41 drives the rotating member 20 to rotate to the position shown in fig. 5, the first magnetic element 31 approaches the third stirrer 303, so that the third stirrer 303 is shifted leftwards, and the second stirrer 302 is shifted rightwards under the influence of the magnetic field of the first magnetic element 31, and reaches the limit position of the second stirrer 302; because the second magnetic element 32 is far away from the first stirrer 301 when the rotating member 20 rotates, the original static equilibrium relationship is broken, and the stirrer can shift leftwards; at this time, the first stirrer 301, the second stirrer 302 and the third stirrer 303 all start to move.

When the motor 41 drives the rotating member 20 to rotate continuously to the position shown in fig. 6, the first magnetic element 31 is located at the center of the mixing position 13, and the first stirrer 301 is deflected rightward under the influence of the magnetic field of the first magnetic element 31; the second stirrer 302 is offset to the middle; the third agitator 303 is kept at a position shifted to the left, reaching the limit position of the third agitator 303.

When the motor 41 drives the rotating member 20 to rotate to the position shown in fig. 7, the first magnetic element 31 drives the second stirrer 302 to shift leftwards, and the limit position of the second stirrer 302 is reached; the first stirrer 301 is kept at a position shifted rightward, and the limit of the first stirrer 301 is reached; since the first magnetic element 31 is far away from the third stirrer 303, the magnetic field of the first magnetic element 31 is insufficient to keep the third stirrer 303 always at the left limit, and the third stirrer 303 breaks the static balance under the influence of gravity and returns to the bottom of the reagent bottle;

as shown in fig. 4, when the motor 41 drives the rotary member 20 to rotate again to the position shown, the first magnetic member 31 moves to the position of the second magnetic member 32 shown in the figure, the first stirring bar 301, the second stirring bar 302, and the third stirring bar 303 start to move again in the above manner, by the above duty cycle, the first stirring bar 301, the second stirring bar 302, and the third stirring bar 303 can stir the reagents in the first reagent bottle 201, the second reagent bottle 202, and the third reagent bottle 203, and stirring of different reagents can be achieved by controlling the rotation speed of the motor 41.

It will be appreciated that the above technical features may be used in any combination without limitation.

The foregoing examples merely illustrate specific embodiments of the utility model, which are described in greater detail and are not to be construed as limiting the scope of the utility model; it should be noted that, for a person skilled in the art, the above technical features can be freely combined, and several variations and modifications can be made without departing from the scope of the utility model; therefore, all changes and modifications that come within the meaning and range of equivalency of the claims are to be embraced within their scope.

Claims (10)

1. A reagent storage device, comprising:

the reagent bin comprises at least two reagent storage units for placing reagent bottles;

a rotating member rotatably provided in the vicinity of the reagent cartridge;

the at least one driving piece comprises magnetic materials and/or nucleophilic materials, is arranged on the rotating piece, is arranged at intervals with the rotating axis of the rotating piece, and corresponds to the connecting line of the at least two reagent storage units along the moving path of the rotating piece so as to provide a dynamically changing magnetic field for the stirrer in the reagent bottle; and

and the driving module is connected with the rotating piece to drive the rotating piece to rotate around the rotating axis.

2. The reagent storage device of claim 1, wherein the rotating member is rotatably disposed below the reagent cartridge and has an axis of rotation parallel to the plane of the reagent cartridge.

3. The reagent storage device of claim 1, wherein the at least one drive member comprises a magnetic material and the magnetic poles are disposed outwardly.

4. The reagent storage device of claim 1, wherein the at least one drive member comprises at least two drive members, the at least two drive members being centrally symmetrically distributed with respect to the axis of rotation.

5. The reagent storage device of claim 1, wherein the rotating member is disc-shaped with an axis coincident with or parallel to the axis of rotation.

6. The reagent storage device according to claim 1, wherein the rotary member has a disk shape, the at least one driving member is provided at an edge of the rotary member, and a magnetic axis thereof is provided along a radial direction of the rotary member.

7. The reagent storage device of claim 1, wherein the at least one drive member is magnetic and configured to: when the at least one driving member rotates with the rotating member, a plane formed by a magnetic axis of the at least one driving member passes through the at least two reagent storage units.

8. The reagent storage device according to claim 1, wherein the line connecting the at least two reagent storage units is straight and perpendicular to the rotation axis.

9. The reagent storage device of claim 1, wherein the at least two reagent storage units comprise at least three reagent storage units, the lines of which are straight and perpendicular to the rotational axis.

10. A sample analyzer comprising the reagent storage device of any one of claims 1-9, and further comprising a housing in which the reagent storage device is mounted.

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