CN219250178U

CN219250178U - Analyte detection device

Info

Publication number: CN219250178U
Application number: CN202222392458.9U
Authority: CN
Inventors: 蔡娅; 王佳; 葛从杰; 秦玉
Original assignee: Nanjing Jingjie Biotechnology Co ltd
Current assignee: Nanjing Jingjie Biotechnology Co ltd
Priority date: 2022-09-05
Filing date: 2022-09-05
Publication date: 2023-06-27
Anticipated expiration: 2032-09-05

Abstract

The utility model relates to the technical field of analyte monitoring, in particular to an analyte detection device, which comprises a shell; the shell is provided with a hollow cavity, and a sensor component is arranged in the cavity; an electronic element is arranged above the sensor assembly, supplies power for the detection device, and converts current signals acquired by the sensor into detection data of an analyte; the shell comprises an upper cover and a lower cover, the upper cover and the lower cover are fixedly connected through an ultrasonic welding mode and/or waterproof glue, the lower surface of the lower cover is provided with an adhesive tape used for being fixed with skin, and a reinforcing adhesive tape is arranged above the adhesive tape. The upper cover and the lower cover have good sealing performance and waterproof performance, so that the internal PCB is prevented from being wetted, and meanwhile, the adhesive tape and the reinforcing adhesive tape are arranged on the lower surface of the lower cover, so that the bonding firmness of the detection device is enhanced, the detection device is prevented from shaking, and the unstable signal transmission is avoided.

Description

Analyte detection device

Technical Field

The utility model relates to the technical field of analyte monitoring, in particular to an analyte detection device.

Background

Some physiological diseases have long disease course and prolonged illness, and certain physiological parameters of patients need to be monitored in real time so as to be better tracked and treated. Such as diabetes, require real-time monitoring of a patient's blood glucose. Accurate blood glucose self-monitoring is a key for realizing good blood glucose control, is beneficial to evaluating the degree of glucose metabolic disturbance of diabetics, and makes a blood glucose reducing scheme, and simultaneously reflects the blood glucose reducing treatment effect and guides the adjustment of the treatment scheme.

The continuous blood glucose monitoring system can continuously detect blood glucose of a patient, the body surface attachment unit is applied to the surface of the skin through the implanter, the sensor electrode attached to the body surface attachment unit is penetrated into subcutaneous tissue, the sensor electrode generates oxidation reaction with in-vivo glucose in interstitial fluid of the patient, an electric signal is formed during the reaction, the electric signal is converted into blood glucose readings through the electronic component, the blood glucose readings are transmitted to the wireless receiver every 1-5 minutes, and corresponding blood glucose data and a map are displayed on the wireless receiver for reference by the patient and doctors.

Typically, the body surface attachment unit includes a sensor and a transmitter, and signals collected by the sensor are transmitted to a mobile phone, a computer or other platforms through a wireless transmission mode after being processed by the transmitter. The body surface attachment unit is usually fixed on the skin surface in an adhesive manner, so that the attachment unit is easy to shake when a user wears the device for a certain period of time, the signal transmission is unstable, and even the attachment unit falls off, so that the use is affected; or the internal PCB is wetted due to poor waterproof performance of the entire attachment unit, thereby affecting signal transmission.

Accordingly, there is a need to provide an analyte detection device.

Disclosure of Invention

In order to solve the technical problem of unstable signal transmission of the attachment unit in the prior art, the utility model provides an analyte detection device.

In order to achieve the above purpose, the technical scheme of the utility model is as follows:

an analyte detection device comprising a housing; the shell is provided with a hollow cavity, a sensor assembly is arranged in the cavity, the sensor assembly comprises a sensor, the sensor is provided with an insertion electrode, the insertion electrode of the sensor extends downwards through the sensor assembly, and the insertion electrode of the sensor is implanted into an object to be detected to react with an analyte to generate a signal; an electronic element is arranged above the sensor assembly, supplies power for the detection device, and converts current signals acquired by the sensor into detection data of an analyte;

the shell comprises an upper cover and a lower cover, the upper cover and the lower cover are fixedly connected through an ultrasonic welding mode and/or waterproof glue, the lower surface of the lower cover is provided with an adhesive tape used for being fixed with skin, and a reinforcing adhesive tape is arranged above the adhesive tape.

Further, a groove is formed in the edge of the upper cover, a protrusion is formed in the edge of the lower cover, and the protrusion is embedded into the groove.

Further, a through hole for the implantation needle to pass through is formed in the upper cover, and a silica gel plug is arranged in the through hole and used for preventing the detection device from being water.

Further, a through hole for inserting the electrode is formed in the lower cover, and the through hole in the lower cover is arranged corresponding to the through hole in the upper cover;

the inner surface of the upper cover is provided with a bulge, and a through hole is arranged in the bulge; the periphery of the through hole of the lower cover is provided with a groove, and the protrusion is embedded into the groove.

Further, a plurality of guide posts are arranged on the upper cover, a plurality of guide sleeves are arranged on the lower cover, and the guide posts extend into the guide sleeves.

Further, the electronic component comprises a PCB and a battery, and the battery is fixed on the surface of the PCB in one of a battery button, welding, gluing, a spring and a structural member extrusion mode.

Further, the battery is a button battery.

Further, the battery button comprises a round base plate and two connecting plates, wherein the connecting plates are symmetrically arranged on two sides of the base plate, one end of each connecting plate is connected with the base plate, the other end of each connecting plate is bent upwards and then bent outwards to form pins, and each connecting plate is connected with the PCB through the corresponding pin; the battery is fixed between the substrate and the PCB board.

Further, the sensor assembly further comprises a sensor base, a silica gel pad and a conductive silica gel column, wherein the silica gel pad base is arranged above the sensor base, and the silica gel pad is arranged above the silica gel pad base; a sensor is arranged between the silica gel pad base and the silica gel pad; an electronic element is arranged above the silica gel pad, a conductive silica gel column is arranged inside the silica gel pad, one end of the conductive silica gel column is electrically connected with the electronic element, and the other end of the conductive silica gel column is electrically connected with the sensor.

Further, the diameter of the middle part of the conductive silica gel column is larger than that of the two end parts thereof, and the diameter of the conductive silica gel column is in smooth transition from one end to the other end.

Further, when the conductive silica gel column is mounted inside the silica gel pad, both ends of the conductive silica gel column extend out of the upper surface and the lower surface of the silica gel pad.

Compared with the prior art, the utility model has the following beneficial effects:

(1) According to the utility model, the upper cover and the lower cover are fixedly connected through ultrasonic welding or waterproof glue, so that the upper cover and the lower cover have good sealing performance and waterproof performance, the internal PCB is prevented from being wetted, and meanwhile, the adhesive tape and the reinforcing adhesive tape are arranged on the lower surface of the lower cover, so that the bonding firmness of the detection device is enhanced, the detection device is prevented from shaking, and the unstable signal transmission is avoided.

(2) According to the utility model, the silica gel plug is arranged in the through hole used for penetrating the implantation needle on the upper cover, so that the waterproof performance of the detection device is enhanced.

(3) The upper cover of the utility model is provided with a groove at the edge, the lower cover is provided with a bulge at the edge, the bulge of the lower cover is embedded into the groove of the upper cover, and meanwhile, the inner surface of the upper cover is provided with a bulge, and a through hole is arranged in the bulge; the periphery of the through hole of the lower cover is provided with a groove, and the bulge at the periphery of the through hole is embedded into the groove at the periphery of the through hole of the lower cover; further enhancing the waterproof performance of the detection device.

Drawings

Fig. 1 is a schematic exploded view of the present utility model.

Fig. 2 is a schematic structural view of the upper cover.

Fig. 3 is a schematic view of an exploded structure of the lower cover and the sensor base.

Fig. 4 is a schematic view of the installation structure of the conductive silica gel column.

FIG. 5 is a schematic view of the sensor base of FIG. 4 with a sensor base added.

Fig. 6 is a schematic structural diagram of an electronic component.

Reference numerals illustrate:

1-upper cover, 101-groove, 102-through hole, 103-guide post, 2-lower cover, 201-protrusion, 202-guide sleeve, 3-sensor base, 4-silica gel pad base, 401-limit table, 5-silica gel pad, 6-conductive silica gel post, 7-sensor, 701-insert electrode, 8-PCB board, 9-battery, 10-battery button, 1001-base plate, 1002-connecting plate, 1003-pin, 11-silica gel plug, 12-adhesive tape, 13-reinforced adhesive tape.

Detailed Description

The technical solutions of the present utility model will be clearly described below with reference to the accompanying drawings, and it is obvious that the described embodiments are not all embodiments of the present utility model, and all other embodiments obtained by a person skilled in the art without making any inventive effort are within the scope of protection of the present utility model.

It should be noted that the relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments should not be construed as limiting the scope of the present utility model unless it is specifically stated otherwise.

Furthermore, it should be understood that the dimensions of the various elements shown in the figures are not necessarily drawn to actual scale, e.g., the thickness, width, length, or distance of some elements may be exaggerated relative to other structures for ease of description.

The following description of the exemplary embodiment(s) is merely illustrative, and is in no way intended to limit the utility model, its application, or uses. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail herein, but where applicable, should be considered part of the present specification.

It should be noted that like reference numerals and letters refer to like items in the following figures, and thus once an item is defined or illustrated in one figure, no further discussion thereof will be necessary in the following figure description.

The detection device of the present utility model is used to monitor the level of an analyte, including, for example, glucose, acetylcholine, amylase, bilirubin, cholesterol, chorionic gonadotropin, creatine kinase (e.g., CK-MB), creatine, DNA, fructosamine, glutamine, growth hormone, blood ketone, lactic acid, oxygen, peroxide, prostate specific antigen, prothrombin, RNA, thyroid stimulating hormone, and troponin. The concentration of drugs such as, for example, antibiotics (e.g., gentamicin, vancomycin, etc.), digitoxin, digoxin, drugs of abuse, alcohol, theophylline, and warfarin may also be monitored. One or more analytes may be monitored with a given sensor; the sensor may also be other suitable sensors.

As shown in FIG. 1, the present utility model provides an analyte detection device comprising a housing; the shell comprises an upper cover 1 and a lower cover 2, the upper cover 1 and the lower cover 2 form a shell with a hollow cavity, and the upper cover 1 and the lower cover 2 are connected through ultrasonic welding, so that the whole waterproof performance of the detection device is good. The upper cover 1 is provided with a through hole 102 for the implantation needle to pass through, and a silica gel plug 11 is arranged in the through hole 102 and used for waterproof of the detection device. The silica gel plug 11 is a stepped cylinder, is installed in the through hole 102 of the upper cover 1 from the inside of the shell, and after the detection device is installed, the silica gel plug 11 is fixed in the through hole to play a waterproof role. The lower cover is provided with a through hole for inserting the electrode, and the through hole on the lower cover is correspondingly arranged with the through hole on the upper cover; the inner surface of the upper cover is provided with a bulge, and a through hole is arranged in the bulge; the periphery of the through hole of the lower cover is provided with a groove, and the protrusion is embedded into the groove. The fixing device is used for fixing the silica gel plug, is favorable for ultrasonic welding, and enhances the waterproof performance of the through hole.

The lower surface of the lower cover 2 is provided with an adhesive plaster 12 for fixing with the skin, and a reinforcing adhesive plaster 13 is arranged above the adhesive plaster 12. The lower surface of the adhesive plaster 12 for fixing with the skin is an adhesive surface which is adhered with the surface of the skin; the upper surface of the adhesive plaster 12 is bonded with a layer of double-sided adhesive tape, and the adhesive plaster 12 is bonded with the lower surface of the lower cover 2. The reinforcing adhesive tape 13 is used for reinforcing the adhesion of the detection device and prolonging the wearing period of the adhesive tape 12 on the user, when the adhesive tape 12 falls off partially in the wearing process, the adhesive tape 13 can be used for assisting the skin-friendly adhesive tape in the wearing process, so that the emitter main body is fixed on the skin of the wearer for a long time without shaking, and stable signal transmission is realized. The skin-friendly adhesive tape and the reinforcing adhesive tape have biocompatibility, so that the rejection phenomenon of users is avoided.

In other embodiments, the upper cover 1 and the lower cover 2 can be connected by waterproof glue in an adhesive mode, so that the sealing performance and the waterproof performance are good. The upper cover 1 and the lower cover 2 can also be connected by adopting a mode of combining ultrasonic welding and waterproof glue. In the process of fixedly connecting the upper cover 1 and the lower cover 2, preferably, a sealing ring is placed in a groove 101 at the edge of the upper cover 1, and after the upper cover 1 and the lower cover 2 are fixedly connected, the sealing ring is extruded so as to fill up the contact surface of the upper cover 1 and the lower cover 2, thereby realizing good sealing.

In other embodiments, the adhesive tape 12 and the lower cover 2 may be fixedly connected by ultrasonic welding, pressing, liquid adhesive bonding, or the like.

As shown in fig. 2 and 3, the edge of the upper cover 1 is provided with a groove 101, the edge of the lower cover 2 is provided with a protrusion 201, and when the upper cover 1 is buckled with the lower cover 2, the protrusion 201 of the lower cover 2 is embedded into the groove 101 of the upper cover 1, so that the waterproof performance between the upper cover 1 and the lower cover 2 is further improved. The upper cover 1 is also provided with two guide posts 103, the lower cover 2 is provided with two guide sleeves 202, and when the upper cover 1 is buckled with the lower cover 2, the guide posts 103 extend into the guide sleeves 202 to provide guiding and positioning functions for the installation of the upper cover 1 and the lower cover 2.

The upper surface of the lower cover 2 is provided with a lug, a through opening is formed in the lug, a sensor assembly is arranged in the opening, an electronic element is arranged above the sensor assembly, the electronic element supplies power for the detection device, and a current signal acquired by the sensor is converted into detection data of an analyte. The sensor assembly comprises a sensor base 3, a silica gel pad base 4, a sensor 7, a silica gel pad 5 and a conductive silica gel column 6. The sensor base 3 is connected with the silica gel pad base 4 through a buckle, and the sensor base 3 is connected with the lower cover 2 through a buckle. A silica gel pad base 4 is arranged above the sensor base 3, and a silica gel pad 5 is arranged above the silica gel pad base 4; as shown in fig. 4, a sensor 7 is arranged between the silica gel pad base 4 and the silica gel pad 5, a plurality of limit grooves are arranged on two sides of the silica gel pad 5, a plurality of limit columns corresponding to the limit grooves are arranged on two sides of the silica gel pad base 4, and a limit table 401 is arranged at the upper end of each limit column; the spacing post wears to establish in the spacing inslot, and spacing platform 401 is located silica gel pad 5 top for fixed silica gel pad 5. Three spaced conductive silica gel columns 6 are arranged inside the silica gel pad 5.

As shown in fig. 5, the sensor 7 has an insertion electrode 701, the insertion electrode 701 of the sensor 7 protrudes downward through the sensor base 3, and the insertion electrode 701 of the sensor 7 is implanted in the analyte to react with the analyte to generate a signal; an electronic element is arranged above the silica gel pad 5, supplies power for the detection device, and converts signals acquired by the sensor 7 into detection concentration of analytes; one end of the conductive silica gel column 6 is electrically connected with the electronic element, and the other end of the conductive silica gel column 6 is electrically connected with the sensor 7.

The diameter of the middle portion of the conductive silica gel column 6 is larger than the diameters of the both end portions thereof, and the diameter of the conductive silica gel column 6 is smoothly transited from one end to the other end. When the conductive silica gel column 6 is mounted inside the silica gel pad 5, the two ends of the conductive silica gel column 6 extend out of the upper surface and the lower surface of the silica gel pad 5, so that the conductive silica gel column 6 has good contact with the sensor 7 and the PCB 8. When the silica gel pad 5 is mounted on the silica gel pad base 4, the conductive silica gel column 6 is in a compressed state so that the conductive silica gel column 6 has good conductive performance.

As shown in fig. 6, the electronic component includes a PCB 8 and a battery 9, wherein the battery is a button cell with 1625 specification, the battery 9 is fixed on the lower surface of the PCB 8 by a cell button 10, the cell button includes a circular substrate 1001 and two connection plates 1002, the connection plates 1002 are symmetrically arranged on two sides of the substrate 1001, one end of each connection plate 1002 is connected with the substrate 1001, the other end of each connection plate 1002 is bent upwards and then bent outwards to form a pin 1003, and the connection plates 1002 are connected with the PCB 8 by the pins 1003; the battery 9 is fixed between the substrate 1001 and the PCB 8. During installation, the battery button 10 is welded on the lower surface of the PCB 8, then the battery 9 is installed, and the battery button 10 can cling the battery 9 to the copper foil on the PCB 8, so that power supply of the PCB 8 is realized.

In other embodiments, the battery 9 may also be fixed to the surface of the PCB 8 by welding, gluing, spring or structural member extrusion. When the welding mode is adopted, the battery can be directly welded on the surface of the PCB, and when the gluing mode is adopted, the battery can be glued on the surface of the PCB by adopting conductive glue; the spring mode is adopted, namely, a spring is arranged on the side surface of the battery, which is away from the PCR plate, and the battery which is contacted with the PCB and conducted by the elasticity of the spring; when adopting the extruded mode of structure, mean through setting up the structure of placing the battery on the PCB surface, the battery is placed in the structure, sets up the extrusion piece on the structure, for example jackscrew, the extrusion piece extrudees the battery to contact and switch on with the PCB.

The detection device implants the insertion electrode 701 into the skin by means of the needle aid, the insertion electrode 701 and an analyte in blood react chemically to obtain an original current signal, the sensor amplifies the original current signal and carries out moving window mean value filtering treatment to obtain a treated current signal, and the treated current signal is further processed by a concentration conversion algorithm to obtain analyte concentration data.

The above embodiments are only for illustrating the technical solution of the present utility model and not for limiting the same, and although the present utility model has been described in detail with reference to examples, it should be understood by those skilled in the art that modifications and equivalents may be made thereto without departing from the scope of the technical solution of the present utility model, which is intended to be covered by the claims of the present utility model.

Claims

1. An analyte detection device comprising a housing; the shell is provided with a hollow cavity, a sensor assembly is arranged in the cavity, the sensor assembly comprises a sensor, the sensor is provided with an insertion electrode, the insertion electrode of the sensor extends downwards through the sensor assembly, and the insertion electrode of the sensor is implanted into an object to be detected to react with an analyte to generate a signal; an electronic element is arranged above the sensor assembly, supplies power for the detection device, and converts current signals acquired by the sensor into detection data of an analyte;

the skin-care device is characterized in that the shell comprises an upper cover and a lower cover, the upper cover and the lower cover are fixedly connected through an ultrasonic welding mode and/or waterproof glue, an adhesive tape used for being fixed with skin is arranged on the lower surface of the lower cover, and a reinforcing adhesive tape is arranged above the adhesive tape.

2. The analyte sensing device of claim 1, wherein the rim of the upper cap is provided with a recess and the rim of the lower cap is provided with a protrusion, the protrusion being embedded in the recess.

3. The analyte sensing device of claim 1, wherein the upper cover is provided with a through hole through which the implant needle passes, and a silica gel plug is disposed in the through hole for waterproofing the sensing device.

4. The analyte detection device of claim 3, wherein the lower cap is provided with a through hole for inserting the electrode therethrough, the through hole of the lower cap being provided corresponding to the through hole of the upper cap;

5. The analyte sensing device of claim 1, wherein the upper cover is provided with a plurality of guide posts and the lower cover is provided with a plurality of guide sleeves, the guide posts extending into the guide sleeves.

6. The analyte sensing device of claim 1, wherein the electronic component comprises a PCB board and a battery, the battery being secured to the surface of the PCB board by one of a button, a weld, an adhesive, a spring, and a structural member compression.

7. The analyte detection device of claim 6, wherein the battery is a button cell.

8. The analyte detection device of claim 6, wherein the battery button comprises a circular base plate and two connecting plates, wherein the connecting plates are symmetrically arranged on two sides of the base plate, one end of each connecting plate is connected with the base plate, and after the other end of each connecting plate is bent upwards, the connecting plates are bent outwards to form pins, and the connecting plates are connected with the PCB through the pins; the battery is fixed between the substrate and the PCB board.

9. The analyte detection device of claim 1, wherein the sensor assembly further comprises a sensor base, a silica gel pad and a conductive silica gel column, the silica gel pad base being disposed above the sensor base, the silica gel pad being disposed above the silica gel pad base; a sensor is arranged between the silica gel pad base and the silica gel pad; an electronic element is arranged above the silica gel pad, a conductive silica gel column is arranged inside the silica gel pad, one end of the conductive silica gel column is electrically connected with the electronic element, and the other end of the conductive silica gel column is electrically connected with the sensor.

10. The analyte detection device of claim 1, wherein the diameter of the middle portion of the conductive silica gel column is greater than the diameter of the two end portions thereof, and the diameter of the conductive silica gel column transitions smoothly from one end to the other.