CN219208702U - Polymer microneedle patch drying mold - Google Patents
Polymer microneedle patch drying mold Download PDFInfo
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- CN219208702U CN219208702U CN202222822678.0U CN202222822678U CN219208702U CN 219208702 U CN219208702 U CN 219208702U CN 202222822678 U CN202222822678 U CN 202222822678U CN 219208702 U CN219208702 U CN 219208702U
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Abstract
The utility model relates to the technical field of biological medicines, in particular to a high polymer microneedle patch drying mould, which comprises a bottom plate, wherein a first hole for placing a microneedle patch is formed in the bottom plate, and a supporting block is arranged on the first hole and is used for supporting the microneedle patch; the pressure plate is provided with a second hole, the microneedle patch is contacted with the outside through the second hole, and the hole wall of one side of the second hole, which is close to the bottom plate, is provided with a step groove; the edge pressing frame, protruding formation edge pressing in the interior circumference of edge pressing frame, edge pressing frame detachable places in the ladder recess department of clamp plate, and the acting force is applyed to the microneedle paster through edge pressing frame and clamp plate and is pressed the sword dry. The edge pressing frame is arranged on the edge pressing frame independently, the edge pressing frame is connected with the pressing plate in a detachable mode, and when the edge pressing needs to be carried out on the microneedle patches of different sizes at different positions of the microneedle patches, the edge pressing frame placed at the step groove in different frame sizes only needs to be replaced, so that the application range of the drying die is enlarged.
Description
Technical Field
The utility model belongs to the technical field of biological medicines, in particular to the field of drying devices of polymer microneedle patches, and more particularly relates to a polymer microneedle patch drying mold.
Background
The types of the microneedles are mainly divided into metal material microneedles and polymer material microneedles from the aspect of materials, the metal material microneedles are formed by cutting and polishing through a metal cutter, and the polymer material microneedles are generally formed by casting polymer material solutions and then drying and dehydrating to form polymer microneedle patches. In the process of drying the polymer microneedle patch, the upper side and the lower side of the peripheral part are exposed to the external environment for drying, the side edges of the peripheral part are also exposed to the external environment for drying, and the middle part is only exposed to the external environment, so that the drying between the peripheral part and the middle part of the polymer microneedle patch cannot be synchronously carried out at the same speed, the peripheral part of the polymer microneedle patch is crimped and wrinkled, the formability of the microneedle patch is damaged, the microneedle patch cannot be well attached to the skin, and the uniform conveying of active ingredients into subcutaneous tissues of the microneedle patch is affected.
The literature named insulin microneedle preparation method research discloses a drying fixture of polymer microneedles, and the drying fixture mainly comprises a polytetrafluoroethylene frame for pressing a microneedle patch without a microneedle part, a pressing plate for performing blade pressing drying on the microneedle patch, and a supporting bottom plate for supporting the microneedle patch. When the micro-needle patch is used, the periphery of the micro-needle patch to be dried is pressed under the polytetrafluoroethylene frame, preliminary drying shrinkage is carried out, the micro-needle patch is placed on the pressing plate after the preliminary drying shrinkage, the pressing plate is clamped with the supporting bottom plate by the dovetail clamp, and edge pressing drying is carried out. The size of the microneedle patch in the drying process can be fixed through the pressure blade drying, so that the curling condition of the microneedle patch is reduced. But when using this drying jig to dry the microneedle paster, the only fixed size's of sword microneedle paster can only be pressed to a set of fixed size's drying jig, to the microneedle paster of equidimension, need the drying jig of different models when pressing the sword to dry, the suitability is relatively poor. And when pressing the sword, need use the forked tail clamp to press the sword with pressing the power that presss from both sides, and the clamping force that the forked tail clamp used after a period of time can drop, can appear the uneven, dry problem that takes place to twist of sword around the microneedle paster.
There is a need for a microneedle patch drying mold that has good applicability and can perform uniform blade pressing.
Disclosure of Invention
The utility model discloses a macromolecule microneedle patch drying mold, which comprises
The micro-needle patch comprises a bottom plate, wherein a first hole for placing the micro-needle patch is formed in the bottom plate, and a supporting block is arranged on the first hole and used for supporting the micro-needle patch;
the pressure plate is provided with a second hole, the microneedle patch is dried by contacting the second hole with the outside, and the hole wall of one side of the second hole, which is close to the bottom plate, is provided with a step groove;
the edge pressing frame, protruding formation edge pressing in the interior circumference of edge pressing frame, edge pressing frame detachable connects in the ladder recess department of clamp plate, applies effort to the microneedle paster through edge pressing frame and clamp plate and presses the sword dry.
Preferably, the edge pressing frame is provided with different frame widths according to the position of the microneedle patch, where the edge pressing is required.
Preferably, the pressing edge is one of a flat-head pressing edge or an inclined-surface pressing edge.
More preferably, the pressing edge is an inclined pressing edge.
Through setting up the pressure sword into the inclined plane and pressing the sword, the dry size of fixed microneedle paster pressure sword that can be fine improves planarization and size homogeneity after the microneedle paster is dry.
Preferably, the bottom plate and the pressing plate are provided with matched threaded holes, and the bottom plate and the pressing plate can be connected through screws.
Preferably, the bottom plate is connected with a guide post, and the pressing plate is provided with a guide hole matched with the guide post.
Preferably, a step layer for embedding the supporting block is arranged on the circumferential side wall of the first hole, and the supporting block is embedded in the step layer.
Preferably, the supporting block comprises a supporting frame and a supporting net, and the supporting net covers one side of the supporting frame and one side of the inner peripheral area of the supporting frame.
Preferably, the hole shape of the first hole on the bottom plate and the second hole on the pressing plate can be rectangular holes, round holes, oval holes, square holes, triangular holes or polygonal holes.
The beneficial effects are that:
(1) In the technical scheme, the inventor independently sets the pressing edge on the pressing edge frame, the pressing edge frame is detachably connected with the pressing plate, and when the pressing edge is required to be carried out at different positions of the microneedle patches with different sizes, the pressing edge frame with different frame sizes placed at the step groove is only required to be replaced. The press blade of the microneedle patch with different sizes can be realized only by matching one set of drying mould with the press blade frame with different sizes, so that the application range of the drying mould is enlarged.
(2) Screw holes are formed in the bottom plate and the pressing plate, and the bottom plate and the pressing plate are detachably connected through screws. When the bottom plate, the edge pressing frame and the pressing plate are used for pressing the edge of the microneedle patch, the acting force among the bottom plate, the edge pressing frame and the pressing plate is increased through the fastening effect of the screws, so that the edge pressing strength is improved, the uniformity of the edge pressing strength is improved, and the crimping degree of the microneedle patch is reduced.
Drawings
Fig. 1 is a schematic view of a part of the structure in embodiment 1.
Fig. 2 is a schematic structural view of the platen and the blade pressing frame in embodiment 1.
Fig. 3 is a schematic structural view of another edge pressing frame.
The device comprises a 1-pressing plate, a 2-supporting block, a 3-bottom plate, a 4-first hole, a 5-second hole, a 6-threaded hole, a 7-supporting net, an 8-supporting frame, a 9-step groove, a 10-first edge pressing frame, an 11-first edge pressing frame, a 12-second edge pressing frame, a 13-second edge pressing frame, a 14-guide column and a 15-guide hole.
Detailed Description
The following is a clear and complete description of the technical solutions in the embodiments of the present utility model, and the embodiments described below are only some embodiments of the technical solutions, but not all embodiments; all other embodiments, based on the embodiments in the technical solution, which are obtained by a person skilled in the art without making any creative effort, are within the protection scope of the present utility model.
Example 1
As shown in fig. 1 and 2, the embodiment discloses a macromolecule microneedle patch drying mold, which comprises a bottom plate 3, a pressing plate 1 and a blade pressing frame. The bottom plate 3 is provided with a first hole 4 for placing the microneedle patch, and the first hole 4 is provided with a supporting block 2 for supporting the microneedle patch. The circumferential side wall of the first hole 4 is provided with a step layer embedded with the supporting block 2, and the supporting block 2 is embedded in the step layer. The supporting block 2 comprises a supporting frame 8 and a supporting net 7, and the supporting net 7 covers one side of the supporting frame 8 and the inner peripheral area of the supporting frame 8. When the microneedle patch is subjected to primary drying or blade pressing drying, the microneedle patch is placed on the supporting block, so that the phenomenon that the middle part of the microneedle patch collapses in the drying process is prevented. The pressure plate 1 is provided with a second hole 5, the microneedle patch is dried by contacting the second hole 5 with the outside, and the hole wall of one side of the second hole 5, which is close to the bottom plate 3, is provided with a step groove 9 for placing a blade pressing frame. In this embodiment, the first hole 4 on the bottom plate 3 and the second hole 5 on the pressing plate 1 are rectangular holes. In this technical scheme, there may be the pressure sword frame of multiple different frame sizes, as shown in fig. 2 and 3, two kinds of pressure sword frames that the frame size is different have been listed in this embodiment, are respectively first pressure sword frame 10 and second pressure sword frame 12, and first pressure sword frame 10 and second pressure sword frame 12's structure is similar, protruding formation first pressure sword 11 on the inner periphery of first pressure sword frame 10, protruding formation second pressure sword on the inner periphery of second pressure sword frame 12, and the difference of first pressure sword frame 10 and second pressure sword frame 12 lies in that the frame width of first pressure sword frame 10 is less, can press the sword to the microneedle paster of great size, and the frame width of second pressure sword frame 12 is great, can press the sword to the microneedle paster of less size. The edge pressing frame is detachably placed at the step groove 9 of the pressing plate 1, acting force is applied to the microneedle patch through the edge pressing frame and the pressing plate 1 to press the edge for drying, the edge pressing is independently arranged on the edge pressing frame, and when the edge pressing is required to be carried out on the microneedle patches of different sizes at different positions of the microneedle patches, the edge pressing frame placed at the step groove 9 is only required to be replaced. The press blade of the microneedle patch with different sizes can be realized only by matching one set of drying mould with the press blade frame with different sizes, so that the application range of the drying mould is enlarged. The pressure sword in this embodiment is the inclined plane pressure sword, through pressing the sword to set up as the inclined plane pressure sword, the dry size of fixed microneedle paster that can be fine improves the planarization and the size homogeneity after the microneedle paster is dry. The bottom plate 3 and the pressing plate 1 are provided with matched threaded holes 6, and the bottom plate 3 and the pressing plate 1 can be connected through screws. When the bottom plate 3 and the pressing plate 1 are detachably connected through the screws and the micro-needle patch is pressed by the bottom plate 3, the pressing edge frame and the pressing plate 1, the acting force between the bottom plate 3, the pressing edge frame and the pressing plate 1 is increased through the fastening effect of the screws, so that the pressing edge strength is improved, the uniformity of the pressing edge strength is improved, and the curling degree of the micro-needle patch is reduced. The bottom plate 3 is connected with a guide post 14, and the pressing plate 1 is provided with a guide hole 15 matched with the guide post 14. Through setting up the cooperation of guide post 14 and guiding hole 15, avoid producing crisscross between clamp plate 1 and the bottom plate 3, improve the roughness that dry mould carries out the pressure sword drying to the microneedle paster. The microneedle patch is torn off from the microneedle female die and is firstly placed on the supporting block, one side, far away from the stepped groove, of the pressing plate is pressed on the periphery of the microneedle patch for preliminary drying, after preliminary drying, a proper edge pressing frame is selected to be connected to the stepped groove of the pressing plate, the edge pressing side of the edge pressing frame is pressed to the microneedle patch, the pressing plate is fastened with the bottom plate through screws, the edge pressing strength is improved, and the edge pressing drying is completed in the time required for placement.
Claims (8)
1. A high polymer microneedle patch drying mold is characterized by comprising
The micro-needle patch comprises a bottom plate, wherein a first hole for placing the micro-needle patch is formed in the bottom plate, and a supporting block is arranged on the first hole and used for supporting the micro-needle patch;
the pressure plate is provided with a second hole, the microneedle patch is dried by contacting the second hole with the outside, and the hole wall of one side of the second hole, which is close to the bottom plate, is provided with a step groove;
the edge pressing frame, protruding formation edge pressing in the interior circumference of edge pressing frame, edge pressing frame detachable connects in the ladder recess department of clamp plate, applies effort to the microneedle paster through edge pressing frame and clamp plate and presses the sword dry.
2. The drying mold for the polymer microneedle patches of claim 1, wherein the edge pressing frame is provided with different frame widths according to the positions of the microneedle patches where the edge pressing is required.
3. The polymeric microneedle patch drying mold of claim 1 or 2, wherein the pressing edge is one of a flat-head pressing edge or a bevel pressing edge.
4. A macromolecular microneedle patch drying mould according to claim 3, wherein the base plate and the pressing plate are provided with matched threaded holes, and the base plate and the pressing plate can be connected by screws.
5. The drying mold for the polymer microneedle patches of claim 4, wherein the bottom plate is connected with a guide post, and the bottom plate is provided with a guide hole matched with the guide post.
6. The drying mold for the polymer microneedle patches of claim 5, wherein a step layer for embedding the supporting block is formed on the circumferential side wall of the first hole, and the supporting block is embedded in the step layer.
7. The drying mold for the polymeric microneedle patches of claim 6, wherein the supporting block comprises a supporting frame and a supporting net, and the supporting net covers one side of the supporting frame and the inner peripheral area of the supporting frame.
8. The drying mold for the polymer microneedle patches of claim 1, wherein the first holes on the bottom plate and the second holes on the pressing plate can be rectangular holes, circular holes, elliptical holes, square holes, triangular holes or polygonal holes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222822678.0U CN219208702U (en) | 2022-10-25 | 2022-10-25 | Polymer microneedle patch drying mold |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222822678.0U CN219208702U (en) | 2022-10-25 | 2022-10-25 | Polymer microneedle patch drying mold |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219208702U true CN219208702U (en) | 2023-06-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222822678.0U Active CN219208702U (en) | 2022-10-25 | 2022-10-25 | Polymer microneedle patch drying mold |
Country Status (1)
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| CN (1) | CN219208702U (en) |
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2022
- 2022-10-25 CN CN202222822678.0U patent/CN219208702U/en active Active
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