CN219208700U - Patch set - Google Patents

Abstract

The utility model belongs to the technical field of patch medicines, and particularly relates to a patch set. The patch set comprises an application patch, wherein the lower surface of the application patch is provided with an adhesive layer, and a medicament unit is arranged on the lower surface of the application patch; the patch set further comprises: a positioning patch, the lower surface of which is provided with a skin-adhering layer, and positioning holes are arranged on the positioning patch; when the site is stacked under the patch, the adhesive layer can adhere to the upper surface of the site, and the drug unit can align with the positioning hole and can be in close contact with the skin through the positioning hole. The patch set can accurately frame and select and determine the administration position by using the positioning patch, so that the administration position is accurately covered by the medicament unit, and the medicament absorption rate and the curative effect of transdermal administration are effectively improved.

Description

Patch set

Technical Field

The utility model relates to the technical field of patch medicines, in particular to a patch set.

Background

In the technical field of transdermal drug delivery, a nano-wafer or a microneedle device is adopted to dredge and open a channel of the stratum corneum of skin, and then a medicament is applied to the dredged area, so that the absorption efficiency of active ingredients can be remarkably improved, and the drug delivery mode is increasingly paid attention to the industry.

In the actual operation process, the size of the dredging channel formed by the nano-wafer or the micro-needle device is small, so that the dredging channel is difficult to observe by naked eyes, the dredged area on the skin is not easy to distinguish, and the situation leads to easy deflection of the medicament application position. In addition, even if the user clearly knows the position of the dredged area, the user cannot easily and accurately cover the medicine patch on the dredged area under the condition that the user does not have a visual field because the medicine patch can block the visual line in the process of applying. These conditions result in the inability of the drug in the patch to accurately cover the area that has been cleared, and thus in poor absorption of the active ingredient and poor therapeutic effects.

Disclosure of Invention

The utility model provides a patch assembly for solving the technical problems of inaccurate medicament application position, poor curative effect and the like. The patch assembly comprises an application patch, wherein an adhesive layer is arranged on the lower surface of the application patch, and a medicament unit is arranged on the lower surface of the application patch; the patch set further comprises: the device comprises a positioning patch, wherein the lower surface of the positioning patch is provided with a skin-adhering layer, and positioning holes are formed in the positioning patch; the adhesive layer is capable of adhering to the upper surface of the site when the site is stacked under the site, and the medicament unit is capable of aligning the locating hole and capable of being brought into close contact with the skin through the locating hole.

Related terms of the above technical solutions are further described below.

Medicament unit: the medicament unit may be a medicament body such as a gel-like medicament, a paste-like medicament, a solid medicament, etc.; the medicament unit may also comprise a drug storage structure, such as a powdered, gel, emulsion drug, held in a liquid by absorbent cotton, or the like, encased by a gas permeable bag.

Adhesive layer, skin layer: the adhesive layer and the skin-adhering layer are used for adhering to the surface, and can be specifically viscose, nano-glue or other suitable coating or substance capable of adhering to the surface.

The patch sets provided herein include a site in addition to the applicator patch. When in use, the skin-sticking layer is used for sticking the positioning patch on the skin surface, so that the area to be dredged is exposed from the positioning hole; then using a nano-wafer or micro-needle device to dredge the region to be dredged in the positioning hole; after dredging, the adhesive layer of the medicine applying patch is adhered downwards to the upper surface of the locating patch, and the medicine applying patch is stacked above the locating patch, and the medicine unit is aligned with the locating hole, namely, the medicine unit is opposite to the dredged area. After stacking the application patches, the dosage units are brought into intimate contact with the skin surface.

According to the utility model, the area to be dredged is accurately framed and determined through the locating patch, and the locating hole on the locating patch can clearly display the area to be dredged, so that the medical staff and patients can observe, confirm and adjust the administration position conveniently; after the position is determined, the positioning patch can protect the skin at the periphery of the positioning hole, so that the nano-wafer or the microneedle device can only dredge the region to be dredged in the positioning hole and open a channel, and the accuracy of drug administration of the patch is effectively improved. In addition, through the overlapping cooperation of the locating patch and the medicine applying patch, the medicine unit can be accurately aligned to the dredged area, so that medicines can fully enter the skin through the dredged area, and the medicine absorption rate and the curative effect of transdermal medicine application are improved.

In a preferred embodiment, the patch is attached to a portion of the edge of the patch, and the unit is capable of aligning the aperture and of making intimate contact with the skin through the aperture when the patch is folded over the patch along the attachment edge. By connecting the application patch and the positioning patch together, the relative position relationship of the application patch and the positioning patch is fixed; when the user folds the patch set along the connecting edge of the patch edge, the stacking positions of the application patch and the positioning patch are relatively fixed, and further, the relative fixation of the positions of the medicament unit and the positioning hole is realized. Through the configuration, the application patches and the positioning patches are connected together to form one-to-one pairing combination, so that the production, the assembly, the packaging and the taking out of the patch set are convenient. Through connecting the limit guide user and folding the paster external member of stacking in fixed position, can effectively improve the accuracy that medicament unit just faces with the locating hole, not only can reduce the operation degree of difficulty, can improve medicine absorptivity and curative effect moreover.

In a preferred embodiment, a protective layer is provided on the lower surface of the patch, the protective layer covering the medicament unit and/or a protective layer is provided on the lower surface of the site. The protective layer may be release paper or other suitable material. Through the configuration, the adhesive layer and the medicament unit of the application patch can be effectively protected, and the skin layer of the positioning patch can also be protected.

In a preferred embodiment, a non-adhesive sheet is arranged at a part of the edge of the adhesive layer and/or a non-adhesive sheet is arranged at a part of the edge of the skin-friendly layer. The non-stick sheet can be strip-shaped, and correspondingly, the non-stick sheet forms a tearing strip at the edge of the patch, thereby facilitating the removal of the application patch and the positioning patch by a user. In addition, the non-stick sheet may be block-shaped, polygonal, fan-shaped, or other suitable shape.

In a preferred embodiment, the site includes a vented zone and/or the application patch includes a vented zone. By the above arrangement, the comfort of the skin during application can be improved.

In a preferred embodiment, a sealing membrane is provided between the medicament unit and the adhesive layer.

In a preferred technical solution, a sealing ring is arranged on the lower surface of the application patch, and the sealing ring is arranged on the periphery of the medicament unit. By the above configuration, the medicine can be concentrated in the dredging area, thereby further improving the medicine absorption efficiency.

In a preferred embodiment, the inner diameter of the sealing ring is not greater than the radius of the positioning hole.

In a preferred embodiment, the medicament unit comprises a liquid-absorbing member. With the above configuration, the medicine unit can better hold the liquid medicine.

In a preferred embodiment, the thickness of the medicament unit is 0.001mm-5mm.

In a preferred embodiment, a locating mark is provided on the upper surface or edge of the site. With the above configuration, the user can more easily and accurately align the medicine unit to the dredging area.

In a preferred embodiment, the patch set further comprises an application unit configured to apply a patch covering the portion of skin exposed from the locating hole when the site is applied to the skin surface. The application unit may be a suitable fluid-like substance such as gel, liquid, emulsion, or the like. Wherein the fluid substance may comprise one or more of a medicament, water, oil. For example, the application unit may be a gel-like medicine or a liquid medicine.

Through above-mentioned configuration, after applying the location paster to the region that skin was to be dredged, spread the unit with smearing and cover in the skin part that exposes from the locating hole, can enough carry out preliminary application to skin, can increase the lubrication degree on skin surface again, make things convenient for the follow-up use nano-wafer or microneedle device to carry out point to skin or slip mediation, improve the smoothness nature of operation.

The present utility model also provides a patch set comprising: the lower surface of the medicine application patch is provided with an adhesive layer; the patch set further comprises: the device comprises a positioning patch, wherein the lower surface of the positioning patch is provided with a skin-adhering layer, and positioning holes are formed in the positioning patch; the adhesive layer is capable of adhering to an upper surface of the site when the site is stacked under the applicator, and the applicator is capable of covering the positioning aperture; and an application unit configured to be able to apply a coating covering a portion of the skin exposed from the positioning hole when the site is applied to the skin surface.

The applicator unit in the patch set includes a fluid-like medicament. Wherein the fluid state may be gel-like, liquid-like, milky or other suitable state. In this paster external member, scribble the unit and can deposit alone and nimble collocation, apply the location paster and treat the region of mediation back at skin, scribble the unit and scribble the skin part of covering and expose from the locating hole, can enough apply medicine to skin again can increase the lubrication degree on skin surface, make things convenient for the follow-up use nano-wafer or microneedle device to carry out the point to skin and carry or slip mediation, improve the smoothness nature of operation.

In a preferred embodiment, the patch is attached to a portion of the edge of the site and the patch is capable of covering the aperture when folded over the patch along the attachment edge.

Drawings

Preferred embodiments of the present utility model are described below with reference to the accompanying drawings, in which:

FIG. 1 is a schematic view of the construction of an application patch in a first embodiment of a patch set of the present utility model;

figure 2 is a schematic view of the construction of a site in accordance with one embodiment of the present utility model.

FIG. 3 is a schematic view of the construction of a patch set according to the first embodiment of the present utility model when the patch set is flattened;

fig. 4 is a schematic structural view of a patch set according to an embodiment of the present utility model when the patch set is folded;

FIG. 5 is a schematic view of the construction of an embodiment of the patch set of the present utility model as applied to the skin;

fig. 6 is a schematic structural view of a patch set according to a third embodiment of the present utility model when the patch set is folded.

List of reference numerals:

1. a patch for applying the medicine; 11. an adhesive layer; 12. a medicament unit; 13. a seal ring; 14. sealing the diaphragm; 15. a protective layer of the patch; 16. a non-stick patch of the patch; 2. a site; 21. a skin layer; 22. positioning holes; 23. a protective layer of the site; 24. a non-stick to the site; 3. connecting edges; 4. a microchannel.

Detailed Description

Preferred embodiments of the present utility model are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present utility model, and are not intended to limit the scope of the present utility model.

It should be noted that, in the description of the present utility model, terms such as "upper", "lower", and the like, refer to directions or positional relationships based on those shown in the drawings, which are merely for convenience of description, and do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model.

Furthermore, it should be noted that, in the description of the present utility model, unless explicitly specified and limited otherwise, the terms "arranged," "configured," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be directly connected, can be indirectly connected through an intermediate medium, and can also be communicated with the inside of two elements. The specific meaning of the above terms in the present utility model can be understood by those skilled in the art according to the specific circumstances.

The utility model provides a patch assembly for solving the technical problems of inaccurate medicament application position, poor curative effect and the like. The patch assembly comprises a medicine application patch, wherein the lower surface of the medicine application patch is provided with an adhesive layer, and a medicine unit is arranged on the lower surface of the medicine application patch; the patch set further comprises: a positioning patch, the lower surface of which is provided with a skin-adhering layer, and positioning holes are arranged on the positioning patch; when the site is stacked below the patch, the adhesive layer can adhere to the upper surface of the site to align the site and to allow the site to be in intimate contact with the skin, and the site can be exposed from the site.

The technical scheme is further described by the following examples.

Example 1

FIG. 3 is a schematic view of the construction of a patch set according to the first embodiment of the present utility model when the patch set is flattened; fig. 4 is a schematic structural view of the patch set of the first embodiment of the patch set of the present utility model when the patch set is folded. As shown in fig. 3 and 4, in a first embodiment, the patch set includes an applicator patch 1 and a site 2 that are attached to each other, with the attachment edge 3 being formed at the junction of the applicator patch 1 and the site 2. When packaged, the application patch 1 and the site 2 of the patch set can be either in a flat package or in a folded stacked package along the connecting edge 3.

The application patch 1 and the positioning patch 2 can be made of non-woven fabrics, and the part of the non-woven fabrics, which is contacted with the skin and the environment, forms an air permeable area; at this time, the patch set has excellent breathability, and can improve the comfort during application. It is easily conceivable that the application patch 1 and the site 2 could also be made of a gas impermeable material such as polyurethane, pu film, etc., and accordingly the patch set would have good water resistance suitable for some pharmaceutical or application situations where it is desired to keep it dry. The application patch 1 and the site 2 may be made of the same material or may be made of different materials. When both are made of the same material, they may be integrally formed by cutting or dicing to simplify the process. In some embodiments, a plurality of vents can be initiated in the applicator patch 1 and site 2 that form a vented zone.

In the first embodiment, the applicator patch 1 and the site 2 are rounded square of the same size, as shown in figure 3. As shown in fig. 3 and 4, the applicator patch 1 is attached to the site 2 by a side edge and forms an attachment edge 3. The applicator patch 1 and site 2 can be folded into alignment along the attachment edge 3 and stacked one on top of the other. In other embodiments, the applicator patch 1 and the site 2 can also be rectangular, circular, oval, polygonal, cartoon characters, or other suitable shapes. It will be readily appreciated that when the applicator patch 1 and the site 2 are designed in other shapes, the applicator patch 1 and the site 2 can be joined together by a corner, a rounded edge, or other suitable partial edge. It should be noted that in some embodiments, the applicator patch 1 and the site 2 can be of different sizes or shapes. Optionally, the site 2 has a size that is larger than the size of the applicator patch 1.

Fig. 1 is a schematic view of the construction of an application patch in a first embodiment of the patch set of the present utility model. As shown in fig. 1, the lower surface of the application patch 1 has an adhesive layer 11. The adhesive layer 11 may be an adhesive, a nano-adhesive, or other suitable coating or substance capable of adhering to a surface. The adhesive layer 11 may be provided on the lower surface of the patch 1 or may be provided around the patch 1.

As shown in fig. 1, a medicine unit 12 is further provided on the lower surface of the patch 1. The medicine unit 12 may be fixed to each other by being adhered to the adhesive layer 11 and the application patch 1, or may be fixed to the lower surface of the application patch 1 by being adhered, pressed, or the like in other suitable manners. In some embodiments, the medicament unit 12 may be a medicament body, such as a gel-like medicament, a paste-like medicament, a solid medicament, or the like. In other embodiments, the medicament unit may also include a drug storage structure, such as a powdered, gel, emulsion medicament encased by a gas permeable pouch. In the first embodiment, the medicine unit includes a liquid absorbing member, which may be absorbent cotton, through which a certain amount of liquid medicine may be held, and may store medicines in various states such as powder, gel, emulsion, paste, etc., so as to expand the application range of the medicine unit.

As shown in fig. 3, the medicine unit 12 has a circular shape. It is readily contemplated that the medicament unit 12 may also be rectangular, polygonal or other suitable shape. Alternatively, the thickness of the medicament unit is 0.001mm-5mm. As shown in fig. 3, the medicament unit 12 is only one and is arranged in the geometrical centre of the application patch 1. It is easily understood that the medicine unit 12 may have a plurality of medicine units 12 arranged in a certain manner on the lower surface of the administration unit 1, such as a rectangular array arrangement or a circumferential array arrangement.

As shown in fig. 1, a seal ring 13 is provided on the outer periphery of the medicine unit 12. The shape of the inner ring of the sealing ring 13 is matched with the shape of the medicament unit 12, so that the medicament unit 12 is better protected, and the medicament is prevented from diffusing and losing around. The sealing ring 13 may be made of foam material, or may be made of other suitable materials such as silica gel. When there are a plurality of the medicine units 12, a separate seal ring 13 may be provided at the periphery of each of the medicine units 12.

As shown in fig. 1, a sealing membrane 14 is provided between the medicine unit 12 and the adhesive layer 11. The sealing membrane 14 can better protect the medicament unit 12, prevent the medicament from penetrating the medicament application patch 1 and volatilizing from the upper surface of the medicament application patch 1, and prevent external water vapor from penetrating the medicament application patch 1 and prevent the medicament from being wetted.

As shown in fig. 1, a protective layer 15 of the application patch is further provided on the lower surface of the application patch 1. The protective layer 15 may be a release paper, a plastic film or other suitable material. In the packaged state, the protective film 15 is attached to the adhesive layer 11, and the protective film covers the medicine unit 12, thereby better protecting the medicine unit 12.

In order to facilitate the access of the application unit 1, as shown in fig. 1, a non-adhesive sheet 16 of an application patch is provided on one side edge of the adhesive layer 11. The non-stick sheet may be made of release paper, plastic film or other suitable material. As shown in fig. 1 and 3, in the first embodiment, the non-adhesive sheet 16 is formed into a strip shape to form a tear strip, so that the tear strip is not easy to adhere to the protective layer 15, and a user can conveniently remove the protective layer 15 from the position of the tear strip. It is easily understood that the non-stick sheet 16 may be provided at one corner of the adhesive layer 11, and that the non-stick sheet 16 may be provided at a part of the edge of the adhesive layer 11 in a block shape.

Figure 2 is a schematic view of the construction of a site in accordance with one embodiment of the patch set of the present utility model. As shown in fig. 2, the lower surface of the site 2 has a skin layer 21. The skin layer 21 is used to adhere the site 2 to the skin surface, and the skin layer 21 can be an adhesive, a nano-gel, or other suitable coating or substance that can adhere to the surface. The skin layer 21 can be applied to the lower surface of the site 2 or can be distributed around the site 2.

As shown in fig. 2, a positioning hole 22 is provided in the site 2. In the first embodiment, the positioning hole 22 has the same circular shape as the medicine unit 12. Optionally, the radius of the positioning hole 22 is not smaller than the inner diameter of the sealing ring 13. It will be readily appreciated that when the medicament unit 12 is of other shape, the locating hole 22 may be of a shape matching that. The shape of the positioning hole 22 may be different from the shape of the medicine unit 12, and it is only necessary to ensure that the medicine unit 12 is completely exposed from the positioning hole 22. When there are multiple drug units 12, multiple positioning holes 22 can be provided at corresponding locations on the site 2, with each positioning hole 22 being located and sized to face and mate with a corresponding drug unit 12.

As shown in figure 2, a protective layer 23 of the site is also provided on the lower surface of the site 2. The protective layer 23 may be a release paper, a plastic film, or other suitable material. In the packaged state, the protective layer 23 is attached to the skin layer 21, thereby better maintaining the adhesion of the skin layer 21.

To facilitate access to the site 2, a non-stick 24 of the site is provided on one side edge of the skin layer 21 as shown in figure 2. The non-stick sheet may be made of release paper, plastic film or other suitable material. As shown in fig. 2 and 3, in the first embodiment, the non-adhesive sheet 24 is formed into a strip shape to form a tear strip, so that the tear strip is not easy to adhere to the protective layer 23, and a user can conveniently remove the protective layer 23 from the position of the tear strip. It is easily understood that the non-stick sheet 24 may be provided at one corner of the skin layer 21, and that the non-stick sheet 24 may be provided in a block shape at a part of the edge of the skin layer 21.

Fig. 5 is a schematic view of the construction of an embodiment of the patch set of the present utility model as applied to the skin. In use, the protective layer 23 of the site is removed from the site at the location of the non-adhesive sheet 24 of the site, as shown in figure 5, with the skin-contacting layer 21 of the site 2 facing the skin. Through the positioning hole 22, the user can conveniently observe the skin from the positioning hole 22, so as to accurately adhere the positioning patch 2 to the skin, and the area to be dredged of the skin is exposed from the positioning hole 22.

After the site 2 is applied, the area to be dredged in the locating hole 22 is dredged and massaged using a nano-wafer or micro-needle device so that a plurality of micro-channels 4 are created on the stratum corneum of the skin.

After the micro-channels 4 are formed, the protective layer 15 of the applicator patch is removed from the site of the patch 16, and the patch 1 is folded over along the connecting edge 3 so that its adhesive layer 11 adheres to the upper surface of the site 2. In the first embodiment, since the size of the application patch 1 is the same as that of the site 2, when the two are stacked up and down, it is only necessary to ensure that the edges of the application patch 1 and the site 2 are aligned, so that the medicament unit 12 is ensured to be in accurate direct contact with the skin in the positioning hole 22, and further the dredged area is ensured to be covered accurately. After the drug unit 12 contacts the skin, the drug can quickly and efficiently permeate under the skin and be absorbed by the skin because the micro-channels 4 dredge the stratum corneum. Therefore, the patch set in the first embodiment can facilitate the user to accurately apply the medicine to the dredged area, thereby effectively improving the absorption efficiency and the curative effect of the medicine. In addition, to further improve the comfort of the skin when the drug is applied, breathable zones, such as vents, may be provided on the applicator patch 1 and site 2.

It is emphasized that by providing the connecting edge 3 between the applicator patch 1 and the site 2, the user can be guided to fold over and stack the applicator patch 1 and the site 2 in a fixed position, thereby ensuring precise alignment of the medicament unit 12 with the positioning aperture 22. When the shapes or sizes of the application patch 1 and the site 2 are different, it is also convenient for the user to easily align the medicament unit 12 precisely with the positioning hole 22 by providing a specific connecting edge 3. To further facilitate alignment between the applicator patch 1 and the site 2, a registration mark can be provided on the upper surface or edge of the site 2. When the application patch 1 is folded along the connecting edge 3, the alignment of the specific position of the application patch 1 with the positioning mark is only required to ensure that the medicament unit 12 is opposite to the positioning hole 22, so that the medicament is opposite to the dredged region.

Example two

Unlike the first embodiment, in the second embodiment, the patch set further includes an application unit, which is configured to be packaged separately, and may be a gel-like, liquid-like, emulsion-like, or other suitable fluid-like substance. Wherein the fluid substance may comprise one or more of a medicament, water, oil. For example, the application unit may be a gel-like medicine or a liquid medicine. The types of the smearing units can be flexibly matched according to the needs.

In application, the site 2 is first applied to the skin surface such that the area to be dredged emerges from the locating hole 22. And then the smearing unit is smeared on the skin part exposed from the positioning hole, so that the smearing unit can not only perform preliminary medicine application on the skin surface, but also increase the lubrication degree of the skin surface. After the smearing is finished, the skin is lifted by a nano-wafer or a micro-needle device or is dredged by sliding. After dredging, the application patch 1 is covered on the positioning patch 2, so that the medicament unit 12 is aligned with the positioning hole and is in close contact with the dredged area through the positioning hole, and further application and nursing of the skin are realized.

Example III

Fig. 6 is a schematic structural view of a patch set according to the second embodiment of the present utility model when the patch set is folded. As shown in fig. 6, unlike the first embodiment, in the third embodiment, the lower surface of the patch 1 for applying medicine is not provided with a unit for applying medicine, and an application unit designed as a separate package is used in cooperation with the patch. The applicator unit in the patch set includes a fluid-like medicament. Wherein the fluid state may be gel-like, liquid-like, milky or other suitable state. The types of the smearing units can be flexibly matched according to the needs.

In application, the site 2 is first applied to the skin surface such that the area to be dredged emerges from the locating hole 22. And then the smearing unit is smeared on the skin part exposed from the positioning hole, and the smearing unit can increase the lubrication degree of the skin surface while applying the medicine to the skin surface. After the smearing is finished, the skin is lifted by a nano-wafer or a micro-needle device or is dredged by sliding. The skin surface is lubricated by the smearing unit, so that the nano-wafer or the micro-needle device can smoothly slide and dredge. After dredging, the application patch 1 is covered on the positioning patch 2, and the smearing unit is stored between the skin and the application patch 1 in a sealing way, so that the medicine can be absorbed continuously.

Thus far, the technical solution of the present utility model has been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of protection of the present utility model is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present utility model, and such modifications and substitutions will fall within the scope of the present utility model.

Claims (14)

1. A patch set, the patch set comprising:

the medicine applying patch comprises a medicine applying patch, a medicine applying unit and a medicine applying unit, wherein the lower surface of the medicine applying patch is provided with an adhesive layer;

wherein the patch set further comprises:

the device comprises a positioning patch, wherein the lower surface of the positioning patch is provided with a skin-adhering layer, and positioning holes are formed in the positioning patch; the adhesive layer is capable of adhering to the upper surface of the site when the site is stacked under the site, and the medicament unit is capable of aligning the locating hole and capable of being brought into close contact with the skin through the locating hole.

2. The patch set of claim 1 wherein the applicator patch is attached to a portion of an edge of the site and the medicament unit is capable of aligning the locating aperture and of being brought into intimate contact with the skin by the locating aperture when the applicator patch and the site are folded over along the attachment edge.

3. A patch set as claimed in claim 1, wherein a protective layer is provided on the lower surface of the applicator patch, the protective layer covering the medicament unit and/or a protective layer is provided on the lower surface of the site.

4. Patch set according to claim 1, characterized in that a non-stick sheet is arranged at a part of the edge of the adhesive layer and/or a non-stick sheet is arranged at a part of the edge of the skin layer.

5. The patch set of claim 1, wherein the site includes a vented zone and/or the applicator patch includes a vented zone.

6. A patch set as claimed in any one of claims 1 to 5, wherein a sealing membrane is provided between the medicament unit and the adhesive layer.

7. A patch set as claimed in any one of claims 1 to 5, wherein a sealing ring is provided on a lower surface of the patch, the sealing ring being provided at the periphery of the medicament unit.

8. The patch set of claim 7, wherein the sealing ring has an inner diameter no greater than a radius of the locating hole.

9. The patch set of any one of claims 1-5, wherein the medicament unit comprises a wicking member.

10. The patch set of any one of claims 1-5, wherein the thickness of the medicament unit is 0.001mm-5mm.

11. A patch set as claimed in any one of claims 1 to 5, wherein locating indicia are provided on an upper surface or edge of the site.

12. The patch set of any one of claims 1-5, further comprising an application unit configured to apply a patch covering a portion of skin exposed from the locating hole when the site is applied to a skin surface.

13. A patch set, the patch set comprising:

the lower surface of the medicine application patch is provided with an adhesive layer;

wherein the patch set further comprises:

the device comprises a positioning patch, wherein the lower surface of the positioning patch is provided with a skin-adhering layer, and positioning holes are formed in the positioning patch; the adhesive layer is capable of adhering to an upper surface of the site when the site is stacked under the applicator, and the applicator is capable of covering the positioning aperture; and

an application unit configured to apply a coating covering a portion of the skin exposed from the locating hole when the site is applied to the skin surface.

14. The patch set of claim 13 wherein the applicator patch is attached to a portion of an edge of the site and the applicator patch is capable of covering the perforation when the applicator patch and the site are folded over along the attachment edge.

Images