CN219150426U

CN219150426U - Sleeve barrel

Info

Publication number: CN219150426U
Application number: CN202223359734.8U
Authority: CN
Inventors: 杜文翔
Original assignee: Shanghai Yingyida Medical Instrument Co ltd; Inventec Appliances Shanghai Corp; Inventec Appliances Pudong Corp; Inventec Appliances Corp
Current assignee: Shanghai Yingyida Medical Instrument Co ltd; Inventec Appliances Shanghai Corp; Inventec Appliances Pudong Corp; Inventec Appliances Corp
Priority date: 2022-12-13
Filing date: 2022-12-13
Publication date: 2023-06-09
Anticipated expiration: 2032-12-13

Abstract

An object of the present utility model is to provide a sleeve adapted to a centrifugal device having a rotor with a radius of rotation, the sleeve comprising: a housing having a top and a base; the inner body is arranged in the shell and is provided with a plurality of grooves, gaps are formed between adjacent grooves through interference configuration, the grooves are cylindrical grooves, each groove is respectively provided with a groove axis and a groove radius, and the groove radii of the adjacent grooves are unequal. The sleeve can be adapted to the centrifugal machine, so that more than two centrifugal tubes with different sizes can be accommodated without replacing the sleeve when the sleeve is used, and the sleeve is provided with an asymmetric limiting structure to prevent unbalance of the centrifugal machine caused by incorrect setting of operators; in addition, the limited space within the centrifuge is utilized to a maximum extent through the interference arrangement, so that the cost of the centrifuge apparatus is reduced.

Description

Sleeve barrel

Technical Field

A sleeve, in particular a sleeve adapted to a centrifuge device and adapted to centrifuge tubes of different sizes simultaneously.

Background

Conventionally, in medical test procedures (e.g., detection of blood Circulating Tumor Cells (CTC)) or molecular biology experiments (e.g., preparation of competent cells, transformation, etc.), a centrifuge is typically used to separate different substances (cells, proteins, DNA, RNA, etc.) from a sample. However, the rotor (rotor) of the centrifuge currently on the market is only suitable for a centrifuge tube with a single size at a time, and when the size of the centrifuge tube is changed, the sleeve and the rotor must be manually changed and balanced again, which is very inconvenient for operators.

Although this problem can be solved by preparing centrifuges for special centrifuge tubes of different sizes, centrifuges are expensive, which increases the cost of the experimental equipment and takes up much operating space. Therefore, it is an important issue to develop a centrifuge tube that can simultaneously carry centrifuge tubes of different sizes and quickly position the tube in a suitable position to achieve an equilibrium state.

Disclosure of Invention

The utility model aims to provide a sleeve which is suitable for a centrifugal device, wherein the centrifugal device is provided with a rotor, the rotor is provided with a rotation radius, and the sleeve comprises an outer shell and an inner body.

The shell is provided with a top and a base; the inner body is provided with a plurality of grooves, and gaps are formed between adjacent grooves through interference configuration; the grooves are cylindrical grooves, each groove is provided with a groove axis and a groove radius respectively, and the groove radii of two adjacent grooves in the grooves are unequal.

Optionally, the housing is a cylinder, an elliptic cylinder or a rectangular cylinder.

Optionally, the axis of the groove is located on a circumference formed by a radius of rotation of the rotor.

Optionally, when the housing is a cylinder, the cylinder has a radius, wherein the radius is less than a sum of the groove radii of the plurality of grooves.

Optionally, when the cross section of the housing is an elliptic cylinder or a rectangular cylinder, the elliptic cylinder and the rectangular cylinder have a major axis and a minor axis, wherein the length of the major axis is smaller than the sum of the radii of the grooves in the plurality of grooves.

Optionally, a length of a gap line of a gap between adjacent two of the plurality of grooves is less than twice a groove radius of any one of the adjacent two of the plurality of grooves.

Optionally, a central angle formed by the notch between two adjacent grooves and the groove axis of any one of the two adjacent grooves is smaller than 180 degrees.

Optionally, the housing further includes at least one limiting member, and the inner body has at least one limiting groove adapted to the limiting member.

Optionally, when the number of the limiting members is greater than or equal to two, at least one of the limiting members has a size different from that of the other limiting members.

Optionally, the sleeve of the present utility model further includes a collar disposed at an outer edge of the top of the housing, the collar having a fixing portion, and the fixing portion is adapted to fix the sleeve and the rotor.

In summary, the sleeve of the utility model can be adapted to a centrifuge, so that more than two centrifuge tubes with different sizes can be accommodated without replacing the sleeve when the sleeve is used, and the sleeve has an asymmetric limit structure to prevent the imbalance of the centrifuge caused by incorrect setting of an operator; in addition, the limited space within the centrifuge is utilized to a maximum extent through the interference arrangement, so that the cost of the centrifuge apparatus is reduced.

Drawings

The accompanying drawings are included to provide a further understanding of the utility model to those skilled in the art, and are incorporated into and constitute a part of this specification. The drawings illustrate exemplary embodiments of the utility model and, together with the description, serve to explain the principles of the utility model. The following is a brief description of the various figures of the utility model:

fig. 1 is a schematic perspective view of a sleeve according to an embodiment of the utility model.

Fig. 2A is a schematic cross-sectional view of a sleeve according to an embodiment of the utility model.

Fig. 2B is a schematic cross-sectional view of a sleeve according to an embodiment of the utility model.

Fig. 3A is a schematic cross-sectional view of a sleeve according to an embodiment of the utility model.

Fig. 3B is a schematic cross-sectional view of a sleeve according to another embodiment of the utility model.

Fig. 3C is a schematic cross-sectional view of a sleeve according to an embodiment of the utility model.

Fig. 3D is a schematic cross-sectional view of a sleeve according to an embodiment of the utility model.

Fig. 4 is a schematic cross-sectional view of a sleeve according to an embodiment of the utility model.

Fig. 5 is a schematic view of a casing structure of a sleeve according to an embodiment of the utility model.

Fig. 6A is a schematic view illustrating an internal body structure of a sleeve according to an embodiment of the utility model.

Fig. 6B is a schematic view of an inner body structure of a sleeve according to an embodiment of the utility model.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. Based on the embodiments of the present utility model, all other embodiments that a person skilled in the art would obtain without making any progressive contribution are within the scope of the utility model.

In view of the problems of the prior art, the present utility model provides a sleeve, please refer to fig. 1-4. The sleeve 1 of the utility model is adapted to a centrifugal device (not shown in the figures), wherein the centrifugal device has a rotor with a radius of rotation, and wherein the sleeve 1 comprises an outer shell 10 and an inner body 20.

It should be noted that the centrifugal device may be, for example, a pendulum type centrifuge or a fixed type centrifuge, and the utility model is mainly described in terms of a pendulum type centrifuge, but the utility model is not limited thereto.

Then, the housing 10 has a top 12 and a base 14, and the base 14 is designed to be closed, because the centrifuge tube may be broken due to excessive centrifugal force during high-speed centrifugation, so that the sample inside flows out or the broken bottle body is thrown out of the sleeve, thereby damaging the machine, so that the closed base 14 can avoid the situation. In addition, the shape of the housing 10 may be a cylinder, an elliptic cylinder or a rectangular cylinder, but the utility model is not limited thereto.

Then, the inner body 20 is disposed inside the casing 10, and the inner body 20 is adhered to the inner periphery of the casing 10 no matter what shape the casing 10 is, so as to maintain the stability of the rotational speed during centrifugation and avoid the damage of the casing 10 and the inner body 20. The inner body 20 has a plurality of adjacent grooves, each having a groove axis and a groove radius. In the preferred embodiment, the number of grooves is two or three (but the utility model is not limited thereto), so that most of the following description mainly describes the case that the inner body 20 has two grooves.

First, please refer to fig. 3A, fig. 3C and fig. 3D for the case of two grooves. The two grooves in the present embodiment are a first groove 210A and a second groove 210B, respectively, wherein the first groove 210A has a first axis O ₁ With a first radius r ₁ The second groove 210B has a second axis O ₂ And a second radius r ₂ And a first radius r ₁ Is not equal to the second radius r ₂ So as to achieve the function that the same sleeve 1 can be applied to centrifuge tubes with two different sizes. Next, the adjacent first groove 210A and second groove 210B are in an interference configuration, and the gap G is generated by the interference configuration. In addition, the first recess 210A and the second recess 210B are substantially cylindrical recesses for matching most centrifuge tube types.

In addition, the case of three grooves is specifically described, please refer to fig. 3B. In addition to the first and

second grooves

210A and 210B, the inner body 20 of the sleeve 1 of the present embodiment may be further provided with a third groove 210C (having a third axis O ₃ And a third radius r ₃ ) Its third radius r ₃ Different from the first radius r ₁ And a second radius r ₂ And is suitable for three centrifuge tubes of different sizes. Alternatively, in another embodiment, the third recess 210C may be the same size as the second recess 210B (i.e., r ₂ ＝r ₃ ) In this case, the sleeve 1 is suitable for use with centrifuge tubes of two different sizes.

In addition, the sizes of the centrifuge tubes with the plurality of grooves can be selected from the group consisting of 50mL centrifuge tubes, 15mL centrifuge tubes, 12mL centrifuge tubes, 2mL centrifuge tubes and 1.5mL centrifuge tubes, and the utility model is not limited thereto.

Next, referring to fig. 2 and 4, the first recess 210A of the embodiment of the present utility model further has a hole 220, because even for centrifuge tubes with the same capacity, such as 50mL centrifuge tubes, the bottom of the first recess may select a centrifuge tube with a sharp bottom or a round bottom according to the experimental requirements, so the design of the hole 220 can enable the first recess 210A to be adapted to more types of centrifuge tubes, and a receiving space S is provided below the hole 220 to receive the bottom of the centrifuge tube, particularly the centrifuge tube with a sharp bottom, by seeing the bottom of the housing 10 and the inner body 20.

Next, please refer to fig. 3A and fig. 3B, so as to more clearly understand the configuration of each groove. First, in order to make centrifugal forces applied to centrifugal tubes of different sizes identical when centrifugal force is applied, please refer to a calculation formula of a relative centrifugal force (relative centrifugal force), wherein n is a rotation speed and R is a rotation radius.

RCF＝1.118×10 ^-5 ×n ² R

As can be seen from the above, the first axis O of the first groove 210A ₁ Second axis O of second groove 210B ₂ Must be located on the circumference C formed by the radius of rotation of the rotor of the centrifuge so that the centrifugal forces experienced by the different sizes of centrifuge tubes remain the same. Similarly, in the embodiment in which the inner body 20 is provided with three (or more) grooves, the axes (O ₁ 、O ₂ 、O ₃ Etc.) must lie on the circumference C.

Then, regarding the interference configuration, although the first groove 210A and the second groove 210B may be configured in a spaced configuration or a fitting configuration, the spaced configuration wastes a lot of space between the housing 10 and the inner body 20; the conforming arrangement is due to the relatively weak joints and the relatively high risk of breakage of the inner body 20 during high speed centrifugation. The sleeve 1 of the present utility model can be better planned in the limited space of the sleeve 1 through the interference configuration, and the following is an example of two grooves and further illustrates some embodiments, but the present utility model is not limited thereto.

Housing example 1: when the housing 10 is a cylinder, the cylinder will have a bottom radius smaller than the first radius r ₁ And a second radius r ₂ Is a sum of (a) and (b).

For example, the bottom radius of the cylinder is 41mm, the first radius r of the first groove 210A ₁ A second radius r of the second groove 210B of 30mm ₂ 16mm, althoughBut a first radius r ₁ With a second radius r ₂ The sum (46 mm) of the first and

second grooves

210A, 210B is larger than the radius (41 mm) of the bottom surface of the cylinder of the housing 10, but the first and

second grooves

210A, 210B are configured to be co-accommodated in one housing 10.

Housing example 2: when the housing 10 is a square column, the length and width of the square representing the bottom surface are the same, and the length (width) is smaller than the first radius r ₁ And a second radius r ₂ Is a sum of (a) and (b).

Housing example 3: when the housing 10 is an elliptic cylinder or a rectangular cylinder, the bottom surface pattern of the elliptic cylinder or the rectangular cylinder has a major axis and a minor axis, and the major axis is smaller than the first radius r ₁ And a second radius r ₂ Is a sum of (a) and (b).

However, it should be understood that, although the interference arrangement does make the most of the space in the sleeve 1, the size of the notch is not limited, and if the notch is too large, the centrifuge tube will be separated from the original position during centrifugation, so the design of the notch is further described in some embodiments and with reference to fig. 3C and 3D, but the utility model is not limited thereto.

Notched example 1: first, please refer to fig. 3C. Regardless of the size of the notch G, the notch G formed by two adjacent grooves has two contacts, the two contacts form a notch line L, and the notch line L must satisfy the following conditions:

(1) The length of the notch line L is less than twice the first radius r ₁ (i.e., L is smaller than the diameter of the circular bottom surface of the first recess 210A, L<2r ₁ ) The method comprises the steps of carrying out a first treatment on the surface of the And

(2) The length of the notch line L is less than twice the second radius r ₂ (i.e., L is smaller than the diameter of the circular bottom surface of the second groove 210B, L<2r ₂ )。

Notched example 2: next, referring to fig. 3D, in the second case, the notches G formed by two adjacent grooves are respectively aligned with the first axis O ₁ And a second axis O ₂ Forming a first central angle theta ₁ With a second central angle theta ₂ And the central angle must satisfy bothThe following conditions were:

(1) Notch G and first axis O ₁ The first central angle theta is formed ₁ Less than 180 degrees (theta) ₁ <180 °); and

(2) Notch G and second axis O ₂ The second central angle theta is formed ₂ Less than 180 degrees (theta) ₂ <180°)。

As can be seen from the above embodiments, the relative relationship between the notch line L and the radius of the groove or the relative relationship between the notch G and the central angle formed by the grooves are used as references, and the area ratio of the notch to the different grooves is the same, so it can be understood that the centrifuge tube can maintain good stability when being placed when the cross-sectional area of the notch is smaller than a certain proportion of the cross-sectional area of any one of the two adjacent grooves.

It is noted that the above description may also be applied to an interference configuration of three grooves (or even more grooves), as shown in fig. 3B. The common point is that the configuration of the notch formed by two adjacent grooves is consistent with the notch design mode no matter how many grooves are formed.

Then, since the centrifugal tube must be symmetrically disposed to maintain the balance state during centrifugation, the housing 10 and the inner body 20 must be designed with a limiting structure for positioning, so as to avoid the situation that the recess is asymmetric due to the misalignment of the operator, and the centrifugal device is easily damaged. First, the housing 10 has at least one limiting member such that the housing 10 and the inner housing 20 have a fixed configuration when combined, and the inner body 20 has at least one limiting groove adapted to the limiting member.

However, in the preferred embodiment, two stop members (110A, 110B) are provided for the housing 10, and the inner body 20 is provided with two stop slots (230A, 230B) that fit the two stop members. Therefore, in the present embodiment, as further described with reference to fig. 5 to 6, the first limiting member 110A is larger than the second limiting member 110B, and the first limiting member 110A is adapted to the first limiting groove 230A, and the second limiting member 110B is adapted to the second limiting groove 230B, and in addition, the housing 10 is combined with the inner body 20 in a sleeved manner. That is, a limiting member is matched with a limiting groove to form a set of limiting structures, and in this embodiment, two sets of limiting structures are provided.

However, the number of the limiting structures is not limited thereto, and a plurality of limiting members (for example, four limiting members are disposed in pairs or uniformly disposed along the inner periphery of the housing 10) may be further disposed for increasing the stability, and when the number of the limiting members is greater than two, at least one of the limiting members may have a size different from that of the other limiting members, so as to achieve the foolproof function. The setting mode of the limiting structure is not limited to this, and the housing 10 may be provided with a concave limiting groove, the inner body 20 may be provided with a convex limiting member, and the housing 10 and the inner body 20 may be combined in a clamping manner.

Finally, referring to fig. 1 again, when the sleeve 1 of the present utility model is adapted to a pendulum centrifuge, the sleeve 1 is further provided with a collar 30, the collar 30 is disposed at an outer periphery of a top of the housing 10, and the collar has fixing portions 310 (the fixing portions 310 on the other side are not shown in the drawings) to fix the sleeve 1 on the rotor, and the fixing portions 310 may be, for example, a screw connection, a rivet connection or a fastening connection to fix the sleeve 1 and the rotor of the centrifuge, but the present utility model is not limited thereto.

In summary, the sleeve of the present utility model can achieve the following effects:

(1) When the centrifugal machine is used, more than two centrifugal tubes with different sizes can be accommodated without replacing the sleeve;

(2) The fool-proof effect is achieved through the asymmetric limiting structure, so that an operator cannot cause unbalanced centrifugal machines due to incorrect setting;

(3) Utilizing the limited space in the centrifugal machine to the greatest extent through the interference configuration; and

(4) Greatly reduces the cost of centrifuge equipment and saves the operation space of a laboratory.

Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made hereto without departing from the spirit and principles of the present utility model.

Claims

1. A sleeve adapted to a centrifugal device, said centrifugal device having a rotor, said rotor having a radius of rotation, and said sleeve comprising:

a housing having a top and a base; and

the inner body is arranged in the shell and is provided with a plurality of grooves, and a gap is formed between two adjacent grooves through interference arrangement;

the grooves are cylindrical grooves, each groove is provided with a groove axis and a groove radius, and the groove radii of adjacent two of the grooves are unequal.

2. The sleeve of claim 1 wherein said housing is a cylinder, an oval cylinder or a rectangular cylinder.

3. The sleeve of claim 1 wherein said groove axis is located on a circumference defined by said radius of rotation of said rotor.

4. The sleeve of claim 2 wherein when said housing is a cylinder, said cylinder has a radius, wherein said radius is less than the sum of said groove radii of a plurality of said grooves.

5. The sleeve of claim 2 wherein when said housing is elliptical or rectangular in cross-section, said elliptical and rectangular cylinders have a major axis and a minor axis, wherein said major axis has a length less than the sum of said groove radii of said plurality of grooves.

6. The sleeve of claim 1 wherein a length of a gap-on-line of one of said gaps between adjacent ones of said plurality of grooves is less than twice a radius of said groove of any one of adjacent ones of said plurality of grooves.

7. The sleeve of claim 1 wherein said notch between adjacent ones of said plurality of grooves and said groove axis of any one of said adjacent ones of said plurality of grooves form a central angle of less than 180 degrees.

8. The sleeve of claim 1 wherein said housing further includes at least one stop and said inner body has at least one stop slot adapted to said stop.

9. The sleeve of claim 8 wherein when said number of stop members is two or greater, at least one of said stop members has a different size than the other of said stop members.

10. The sleeve of claim 1 further comprising a collar disposed on an outer edge of said top portion of said housing, said collar having a securing portion adapted to secure said sleeve to said rotor.