CN219099193U

CN219099193U - Large-scale production device for mesenchymal stem cell secretion factors

Info

Publication number: CN219099193U
Application number: CN202320010149.2U
Authority: CN
Inventors: 郭天欢; 赵炳榛; 黄莹莹
Original assignee: Henan Guoxin Biotechnology Co ltd
Current assignee: Henan Guoxin Biotechnology Co ltd
Priority date: 2023-01-04
Filing date: 2023-01-04
Publication date: 2023-05-30
Anticipated expiration: 2033-01-04

Abstract

The utility model discloses a large-scale production device of mesenchymal stem cell secretion factors, and belongs to the technical field of cell culture devices. The large-scale production device for the mesenchymal stem cells secretion factors comprises a box body, wherein a plurality of culture chambers are arranged in the box body, an installation box is arranged at the inner lower part of each culture chamber, a culture tray is detachably connected to the upper part of each installation box, a heating device is arranged at the lower part of each installation box, each heating device comprises a heating wire, the heating wires are powered through a storage battery, an installation groove is formed in the lower part of each installation box, the heating wires are arranged in the installation groove, and a baffle is fixedly connected to the front end of each installation box; according to the utility model, through the heating device, the heating and heat preservation effects can be achieved, so that the internal and external temperature changes are not too large when the culture tray is taken out, and the problem that the culture quality is possibly affected due to temperature difference when the culture tray is taken out in the prior art is solved.

Description

Large-scale production device for mesenchymal stem cell secretion factors

Technical Field

The utility model relates to the technical field of cell culture devices, in particular to a large-scale production device of mesenchymal stem cell secretion factors.

Background

Hypoxia culture refers to a culture state in which the oxygen content in cells is lower than that in air, and the change of the oxygen content is one of the most important regulators in the whole life cycle, and extends from embryo development, maintenance of normal body functions, to pathological processes such as diseases and aging, wherein hypoxia is the most common basic environment.

In the chinese patent application No. 201820538680.6, a hypoxia incubator is proposed, and the main problems of the patent are: in this patent, just place the culture medium at will in the culture chamber, operating personnel need carry out and get and put the operation and just can accomplish getting of whole culture medium and put many times, and is more troublesome, makes getting of culture medium put the speed slower, has consequently influenced stem cell culture's efficiency, and long-time getting is put the operation and is also made external air enter into the culture chamber simultaneously easily, also easily influences stem cell culture's quality.

The utility model patent in China with the application number of CN202220849417.5 discloses a low-oxygen culture device for large-scale production of stem cells, and the device can pull a culture disc out of an incubator, so that all culture mediums in the incubator can be taken and placed, thereby greatly facilitating the taking and placing of the culture mediums by operators, solving the problem of slow taking and placing operation caused by the need of taking and placing the culture mediums one by one, and solving the problem.

However, there are other problems that the temperature needs to be maintained during the culture process, and the quality of the culture may be affected by the temperature difference when the culture dish is taken out, so that improvement is required.

Disclosure of Invention

The utility model aims to solve the problem that the culture quality is possibly affected by temperature difference when a culture dish is taken out in the prior art, and provides a large-scale production device for mesenchymal stem cell secretion factors.

In order to achieve the above purpose, the present utility model adopts the following technical scheme:

the large-scale production device for the mesenchymal stem cells secreting factors comprises a box body, a plurality of culture chambers are arranged in the box body, each culture chamber is provided with an installation box at the inner lower part, a culture tray is detachably connected to the upper part of each installation box, a heating device is arranged at the lower part of each installation box and comprises a heating wire, and the heating wires are powered by a storage battery.

Preferably, the lower part of the installation box is provided with an installation groove, and the heating wire is arranged in the installation groove.

Preferably, the front end fixedly connected with baffle of mounting box, the front lower part of baffle is provided with the draw-in groove, the battery both sides all are provided with the card strip, phase-match between card strip and the battery.

Preferably, the culture dish is placed on the upper portion of the mounting box, a placing groove is formed in the inner bottom of the culture dish, and handles are fixedly connected to the tops of two sides of the culture dish.

Preferably, the inner bottom surface of the culture room is fixedly connected with a guide rail, and the bottom of the mounting box is in sliding connection with the guide rail.

Preferably, a fixing plate is arranged at the upper part of each culture chamber, and the fixing plates are fixedly connected with the box body.

Compared with the prior art, the utility model provides a large-scale production device for mesenchymal stem cell secretion factors, which has the following beneficial effects.

1. According to the utility model, through the heating device, the heating and heat preservation effects can be achieved, so that the internal and external temperature changes are not too large when the culture tray is taken out, and the problem that the culture quality is possibly affected due to temperature difference when the culture tray is taken out in the prior art is solved.

Additional advantages, objects, and features of the utility model will be set forth in part in the description which follows; and will be apparent to those skilled in the art in part based upon a review of the following; alternatively, the teachings may be directed to practice of the present utility model.

Drawings

Fig. 1 is a schematic diagram of the overall structure of the present utility model.

Fig. 2 is a schematic diagram of the overall structure of the present utility model.

Fig. 3 is a partially disassembled structure of the present utility model.

Fig. 4 is an enlarged schematic view of the structure of fig. 3 a according to the present utility model.

Fig. 5 is a partially disassembled structure of the present utility model.

Fig. 6 is a schematic structural view of the case according to the present utility model.

In the figure:

1. a case; 2. a fixing plate; 3. a baffle; 4. a storage battery; 5. a placement groove; 6. a guide rail; 7. a culture tray; 8. a handle; 9. a mounting box; 10. a heating wire; 11. a clamping groove; 12. clamping strips; 13. and a mounting groove.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments.

Referring to fig. 1 to 6, the mesenchymal stem cell secretion factor mass production device comprises a box body 1, a plurality of culture chambers are arranged in the box body 1, an installation box 9 is arranged at the inner lower part of each culture chamber, a culture tray 7 is detachably connected to the upper part of the installation box 9, a heating device is arranged at the lower part of the installation box 9 and comprises a heating wire 10, and the heating wire 10 is powered by a storage battery 4.

In the specific embodiment of the present utility model, the storage battery 4 and the heating wire 10 are electrically connected, and a controller is provided therein for controlling the temperature. When the culture medium needs to be taken out, if the external temperature is smaller than the culture temperature, the heating wire 10 is used for heating the mounting box 9, and then the culture medium can not be affected by the temperature difference when the culture medium is taken out.

An oxygen sensor, a humidity sensor, an illumination sensor and a temperature sensor are also arranged in the culture room, and the equipment matched with the oxygen sensor, the humidity sensor, the illumination sensor and the temperature sensor are used for regulating and controlling, and the setting scheme is the same as that of the prior art.

The mounting groove 13 has been seted up to the lower part of mounting box 9, and heater strip 10 sets up in the inside of mounting groove 13.

The front end fixedly connected with baffle 3 of mounting box 9, the front lower part of baffle 3 is provided with draw-in groove 11, and battery 4 both sides all are provided with card strip 12, assorted between card strip 12 and the battery 4.

Through being the joint between battery 4 and the baffle 3 that set up, can conveniently dismantle battery 4 and charge, perhaps take off battery 4 when the difference in temperature is not big to this lightens the weight of mounting box 9, is convenient for get and put.

The culture dish 7 is placed on the upper portion of the mounting box 9, the inner bottom of the culture dish 7 is provided with a placing groove 5, and handles 8 are fixedly connected to the tops of the two sides of the culture dish 7.

Through setting up standing groove 5, can be used for placing the culture medium, through placing culture dish 7 on mounting box 9, can conveniently change culture dish 7 to the culture dish 7 of convenient use not equidimension standing groove 5.

The inner bottom surface of the culture room is fixedly connected with a guide rail 6, and the bottom of the installation box 9 is in sliding connection with the guide rail 6.

Through the guide rail 6 that sets up, can make the installation box 9 slide, be convenient for take off the installation box 9, be convenient for then take off the culture medium. The use state and principle are the same as those of the drawer.

The upper portion of every cultivates the room all is provided with fixed plate 2, fixed plate 2 and box 1 fixed connection.

The foregoing is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical scheme of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.

In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present utility model. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the different embodiments or examples described in this specification and the features of the different embodiments or examples may be combined and combined by those skilled in the art without contradiction.

While embodiments of the present utility model have been shown and described above, it will be understood that the above embodiments are illustrative and not to be construed as limiting the utility model, and that variations, modifications, alternatives and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the utility model.

Claims

1. The large-scale production device for mesenchymal stem cell secretion factors comprises a box body (1), and is characterized in that a plurality of culture chambers are arranged in the box body (1), each culture chamber is provided with an installation box (9) at the inner lower part, a culture dish (7) is detachably connected to the upper part of each installation box (9), a heating device is arranged at the lower part of each installation box (9), the heating device comprises a heating wire (10), and the heating wire (10) is powered through a storage battery (4).

2. The mesenchymal stem cell secretion factor mass production device according to claim 1, wherein the lower part of the installation box (9) is provided with an installation groove (13), and the heating wire (10) is arranged in the installation groove (13).

3. The mesenchymal stem cell secretion factor large-scale production device according to claim 1, wherein the front end of the installation box (9) is fixedly connected with a baffle plate (3), a clamping groove (11) is formed in the lower portion of the front face of the baffle plate (3), clamping strips (12) are arranged on two sides of the storage battery (4), and the clamping strips (12) are matched with the storage battery (4).

4. The large-scale production device of mesenchymal stem cell secretion factors according to claim 1, wherein the culture dish (7) is placed on the upper portion of the installation box (9), a placing groove (5) is formed in the inner bottom of the culture dish (7), and handles (8) are fixedly connected to the tops of two sides of the culture dish (7).

5. The large-scale production device of mesenchymal stem cell secretion factors according to claim 1, wherein the inner bottom surface of the culture chamber is fixedly connected with a guide rail (6), and the bottom of the installation box (9) is in sliding connection with the guide rail (6).

6. The device for mass production of mesenchymal stem cell secretion factors according to claim 1, wherein a fixing plate (2) is arranged at the upper part of each culture chamber, and the fixing plate (2) is fixedly connected with the box body (1).