CN219091165U - Integrated manual solid-phase microextraction device - Google Patents

Abstract

The utility model relates to an integrated manual solid-phase microextraction device, which comprises a workbench, wherein the workbench is provided with an extraction mechanism and an aging mechanism, and also comprises a probe and a headspace bottle which are matched with the extraction mechanism for use, the inside of the probe is provided with a fiber probe, the lower end of the fiber probe penetrates out of the bottom end of the probe, the bottom of the fiber probe is provided with a fiber, the aging mechanism comprises a vertically through aging channel, the top end of the aging channel extends out of the top surface of the workbench, an aging port is arranged at the top end of the aging channel, and a carrier gas inlet pipe is arranged in the workbench and communicated with the bottom end of the aging channel, an electromagnetic valve is arranged in the workbench and is in control connection with the carrier gas inlet pipe, the probe can be inserted into the aging channel from the aging port, and an aging heater is arranged in the workbench and is connected with the outer wall of the aging channel.

Description

Integrated manual solid-phase microextraction device

Technical Field

The utility model belongs to the technical field of solid-phase microextraction, and particularly relates to an integrated manual solid-phase microextraction device.

Background

The solid phase microextraction technology is based on the use of fused quartz fiber coated with a stationary phase to adsorb and enrich substances to be detected in a sample, and is widely applied to the fields of environmental sample detection, analysis of food trace components, drug detection and the like. The principle of solid-phase microextraction method is that based on the equilibrium distribution of the object to be measured between the stationary phase and the water phase, fused quartz optical fiber or other materials are used as matrix support, the characteristic of similar compatibility is adopted, the surface of the substrate is coated with thin layers of polymer stationary phases with different properties, and the object to be measured is extracted, enriched, sampled and analyzed in a direct or headspace mode. The fibers enriched in the analyte are then transferred directly to the instrument, desorbed in a certain manner (typically thermal desorption, or solvent desorption), and then subjected to separation analysis. The solid phase microextraction process flow generally comprises an extraction process and a desorption process, wherein the extraction process comprises the steps that extraction fibers with an adsorption coating are exposed to a sample for extraction; the desorption process comprises inserting an extractor needle to complete the extraction process into a gasification chamber of a gas chromatography sample injection device, exposing the extracted fiber to a high-temperature carrier gas, and continuously desorbing the extract to enter a subsequent gas chromatography. The solid phase microextraction device is similar to a microsyringe of gas chromatography, the extraction head is coated with a solid phase microextraction coating on a quartz fiber, a thin stainless steel tube is sleeved outside the extraction head to protect the quartz fiber from being broken, and the fiber head can stretch in the steel tube. Immersing the fiber head in the sample solution or the headspace gas for a period of time, stirring the solution at the same time to accelerate the balance between the two phases, taking out the fiber head after the balance, inserting the fiber head into a gas chromatograph vaporization chamber, and thermally desorbing substances adsorbed on the coating. After the extracted matter is desorbed in the vaporizing chamber, it is led into chromatographic column via mobile phase to complete the extraction, separation and concentration. Like chinese patent CN213823546U, a solid-phase microextraction device, including the workstation, the workstation surface inlays and is connected with the heating plate, workstation left side fixedly connected with support frame, the oscillator is installed on the support frame right side, set up the inside groove in the support frame, can dismantle in the support frame and be connected with the screw rod, the screw rod top runs through the support frame and the screw rod top bonds there is the carousel, the screw rod can be dismantled and be connected with the removal frame, removal frame sliding connection has the spout, the spout is seted up on the support frame right side, removal frame right side fixedly connected with mount, the through-hole has been seted up to the mount, through-hole sliding connection has the extractor. The rotating disc can enable the extractor to move up and down in the fixing frame and be inserted into the sample cup for micro extraction, so that the phenomenon that the extraction head breaks due to careless operation when a person directly takes the extractor for use can be avoided; the heating plate and the vibrator cooperate to raise the flow speed and temperature of the sample in the sample cup, thereby improving the micro-extraction effect. However, in the above technical solution, only the extraction process is solved, and in actual use, an aging process, i.e. cleaning the fiber filaments, is usually performed, so that after the solid-phase microextraction device is used, an operator needs to use an additional sample inlet of a gas chromatograph to complete the aging process, and the steps are relatively complicated.

Disclosure of Invention

The utility model provides an integrated manual solid-phase microextraction device, which aims to improve the existing solid-phase microextraction device with only a microextraction function, and an aging mechanism is arranged on a workbench, so that the problem that an operator usually needs to finish an aging process by additionally using a sample inlet of a gas chromatograph after the solid-phase microextraction device is used in the prior art is solved, and the steps are complicated.

The utility model provides an integrated manual solid-phase microextraction device, which adopts the following technical scheme:

the utility model provides an integral type manual solid phase microextraction device, includes the workstation, the workstation is provided with extraction mechanism and ageing mechanism, still includes probe and the headspace bottle that cooperates the use with extraction mechanism, the headspace bottle is used for installing the sample, the probe can insert in the headspace bottle, the inside cellosilk that is provided with the lower extreme and wears out the probe bottom of probe the probe bottom is provided with the cellosilk, ageing mechanism includes that the top stretches out the ageing passageway of vertical link up of workstation top surface, the ageing mouth that sets up on ageing passageway top and sets up in the workstation and with the carrier gas intake pipe of ageing passageway bottom intercommunication, be provided with the solenoid valve in the workstation, solenoid valve and carrier gas intake pipe control connection, the probe can be followed ageing mouth and inserted in the ageing passageway, be provided with ageing heater in the workstation, ageing heater connection ageing passageway outer wall.

Preferably, the extraction mechanism comprises an extraction port embedded at the top of the workbench and a magnetic stirring heating table arranged inside the workbench and connected with the bottom of the extraction port, the top end of the extraction port is opened, and the extraction port is used for inserting and fixing a headspace bottle.

Preferably, the top of the workbench is embedded with an inclined control screen, and the control screen is connected with the magnetic stirring heating table, the aging heater and the electromagnetic valve in a control manner.

Preferably, the top of the probe is fixedly provided with a handle push rod, a hand holding cylinder connected with the handle push rod in a sliding way is arranged outside the handle push rod, the probe can extend out of the bottom end of the hand holding cylinder, and the fiber yarn can be vertically inserted into a headspace bottle and is fixed on the upper part of the headspace bottle.

Preferably, the bottleneck of headspace bottle department can dismantle and be connected with bottleneck adapter, bottleneck adapter middle part has seted up vertical spacing passageway that link up, the cellosilk can insert in the headspace bottle after passing spacing passageway.

Preferably, the bottom of the bottle mouth adapter is provided with a connecting groove, the inner diameter of the connecting groove is matched with the diameter of the bottle cap of the headspace bottle, the bottle mouth adapter can be sleeved with the bottle cap of the headspace bottle and is stable above the headspace bottle, and the limiting channel is positioned at the center of the bottle mouth.

Preferably, the bottle mouth adapter top is provided with a fixed slot, the limiting channel is arranged at the bottom of the fixed slot, the fixed slot is internally provided with a sample introduction guide protruding out of the bottle mouth adapter top, the sample introduction guide is internally provided with an auxiliary channel, and the auxiliary channel is communicated with the limiting channel.

Preferably, the bottom of the hand holding cylinder is detachably embedded into the top of the sample introduction guide, and the probe can extend out of the bottom end of the hand holding cylinder and be inserted into the auxiliary channel.

Compared with the prior art, the utility model has the following technical effects:

1. according to the integrated manual solid-phase microextraction device provided by the utility model, the extraction mechanism and the aging mechanism are simultaneously arranged in the workbench, the extraction mechanism is used for solid-phase microextraction, the aging mechanism is used for cleaning the fiber filaments, after the fiber filaments are inserted into the aging channel, the aging heating is carried out by applying a high-temperature condition to desorb volatile substances which are remained and adsorbed on the fiber filaments and taking away the desorbed impurities by utilizing the carrier gas inlet pipe, so that the fiber filaments approach to a zero adsorption state, the solid-phase microextraction function and the aging function are integrated, an operator does not need to use a sample inlet of a gas chromatograph to complete the aging process or manually construct the aging device, and the steps are simpler.

2. According to the integrated manual solid-phase microextraction device provided by the utility model, the fixed headspace bottle in the extraction port is heated through the magnetic stirring heating table, the sample amount in the headspace bottle is not more than half of the solvent in the headspace bottle, the fiber filaments are fixed at the inner top of the headspace bottle, the sample is heated without being contacted with the sample, the temperature is kept constant for a certain time, and volatile substances volatilize and are adsorbed on the fiber filaments, so that the solid-phase microextraction function is completed, and in the solid-phase microextraction process, a rotor matched with the magnetic stirring heating table is added into the headspace bottle for stirring, so that the functions are various.

3. The integrated manual solid-phase microextraction device provided by the utility model has higher automation degree by arranging the control screen to control the conditions such as aging temperature, carrier gas control, extraction temperature, constant temperature time, balance time, stirring speed and the like by using a program.

4. According to the integrated manual solid-phase microextraction device provided by the utility model, the handle push rod is arranged for installing the probe, and the hand-held cylinder is manually held, so that the handle push rod can be pressed down, and the fiber filaments extending out of the bottom of the operation probe move in the vertical direction in the headspace bottle.

5. According to the integrated manual solid-phase microextraction device, the bottleneck adapter is arranged at the bottleneck of the headspace bottle, the depth of the probe inserted into the headspace bottle is reduced through the bottleneck adapter, so that the fiber wires are fixed at the upper part in the headspace bottle and do not contact with a sample, the probe insertion position can be positioned, and the probe is inserted into the headspace bottle from the central shaft after penetrating into the limiting channel.

6. The bottleneck adapter and the headspace bottle in the integrated manual solid-phase microextraction device are connected in a sleeved mode, so that the integrated manual solid-phase microextraction device is more stable and convenient to operate.

7. According to the integrated manual solid-phase microextraction device provided by the utility model, the bottleneck adapter is H-shaped, the top of the bottleneck adapter is provided with the fixing groove for installing the sample introduction guide, the auxiliary channel of the sample introduction guide is used for further adjusting the depth of inserting the contact pin into the headspace bottle, and when the probe is inserted, the probe is almost completely positioned in the auxiliary channel and the limiting channel and used for fixing the probe.

8. The bottom of the hand holding cylinder in the integrated manual solid-phase microextraction device is detachably embedded into the sample introduction guide, and is used for assisting in positioning the hand holding cylinder and the handle push rod so as to facilitate the vertical insertion of the probe into the headspace bottle.

Drawings

FIG. 1 is a schematic diagram of the overall structure of an integrated manual solid phase microextraction device of the present utility model;

FIG. 2 is a schematic cross-sectional view of an integrated manual solid phase microextraction device of the present utility model;

FIG. 3 is a schematic illustration of the connection of a headspace vial and probe of the present utility model.

Reference numerals:

1. a work table; 2. an extraction mechanism; 3. an aging mechanism; 4. a probe; 5. a headspace bottle; 6. a fiber yarn; 7. an aging tunnel; 8. a carrier gas inlet pipe; 9. an electromagnetic valve; 10. an aging heater; 11. an extraction port; 12. a magnetic stirring heating table; 13. a control screen; 14. a handle push rod; 15. a finish adapter; 16. a limiting channel; 17. a connecting groove; 18. a fixing groove; 19. a sample introduction guide; 20. holding the cylinder; 21. an aging port; 22. and an auxiliary channel.

Detailed Description

In order to make the objects, technical solutions and advantages of the present utility model more apparent, the technical solutions of the present utility model will be clearly and completely described below with reference to the specific embodiments of the present application and with reference to the accompanying drawings.

The utility model provides an integral type manual solid phase microextraction device, including workstation 1, workstation 1 is provided with extraction mechanism 2 and ageing mechanism 3, still include probe 4 and headspace bottle 5 that use with extraction mechanism 2 cooperation, the inside cellosilk 6 probe 4 bottom that is provided with of probe 4 bottom is worn out to the lower extreme to probe 4 is provided with cellosilk 6, ageing mechanism 3 includes that the top stretches out the ageing passageway 7 of vertical link up of workstation 1 top surface, the ageing mouth 21 that sets up at ageing passageway 7 top and the carrier gas intake pipe 8 that sets up in workstation 1 and communicate with ageing passageway 7 bottom, be provided with solenoid valve 9 in the workstation 1, solenoid valve 9 and carrier gas intake pipe 8 control are connected, probe 4 can insert ageing passageway 7 from ageing mouth 21, be provided with ageing heater 10 in the workstation 1, ageing heater 10 connects ageing passageway 7 outer wall. Through setting extraction mechanism 2 and ageing mechanism 3 in workstation 1 simultaneously, extraction mechanism 2 is used for solid phase microextraction, ageing mechanism 3 is used for wasing fiber yarn 6, after fiber yarn 6 inserts ageing passageway 7, ageing heating is through applying the high temperature condition and is the volatile matter desorption that remains adsorbed on fiber yarn 6, and take away the impurity of desorption with carrier gas intake pipe 8, make fiber yarn 6 approach zero adsorption state, make the utility model integrate solid phase microextraction function and ageing function, the operator no longer need to borrow the sample inlet of gas chromatograph in addition to accomplish ageing process or manual the setting up ageing device, the step is comparatively simple and convenient.

The extraction mechanism 2 comprises a plurality of extraction ports 11 embedded in the top of the workbench 1 and a magnetic stirring heating table 12 arranged in the workbench 1 and connected with the bottom of the extraction ports 11, the top ends of the extraction ports 11 are opened, and the extraction ports 11 are used for inserting and fixing the headspace bottles 5. The headspace bottle 5 fixed in the extraction port 11 is heated by the magnetic stirring heating table 12, the sample amount in the headspace bottle 5 is not more than half of the solvent in the headspace bottle 5, the fiber filaments 6 are fixed at the inner top of the headspace bottle 5, the sample is not contacted with the sample, the temperature is constant for a certain time, volatile substances volatilize and are adsorbed on the fiber filaments 6, so that the solid-phase microextraction function is completed, in the solid-phase microextraction process, the rotor matched with the magnetic stirring heating table 12 is added into the headspace bottle 5, stirring is carried out, and the functions are various.

The top of the workbench 1 is embedded with an inclined control screen 13, and the control screen 13 is in control connection with the magnetic stirring heating table 12, the aging heater 10 and the electromagnetic valve 9. The control screen 13 is arranged to control the conditions of aging temperature, carrier gas control, extraction temperature, constant temperature time, balance time, stirring speed and the like by using a program, so that the degree of automation is high.

The top of the probe 4 is fixedly provided with a handle push rod 14, a hand holding cylinder 20 which is connected with the handle push rod in a sliding way is arranged outside the handle push rod 14, the probe 4 can extend out of the bottom end of the hand holding cylinder 20, and the fiber yarn 6 can be vertically inserted into the headspace bottle 5 and fixed on the upper part of the headspace bottle 5. By providing the handle push rod 14 for installing the probe 4 and manually holding the hand grip 20, the handle push rod 14 can be pressed down, thereby operating the filament 6 extending from the bottom of the probe 4 to move in the vertical direction in the headspace bottle 5.

The bottleneck of the headspace bottle 5 is detachably connected with a bottleneck adapter 15, a vertically-through limiting channel 16 is formed in the middle of the bottleneck adapter 15, and the fiber wires 6 can pass through the limiting channel 16 and then are inserted into the headspace bottle 5. By providing the bottleneck adapter 15 at the bottleneck of the headspace bottle 5, the depth of the probe 4 inserted into the headspace bottle 5 is reduced by the bottleneck adapter 15, so that the fiber yarn 6 is fixed at the upper part in the headspace bottle 5 without contacting with a sample, the insertion position of the probe 4 can be positioned, and the probe 4 is inserted into the headspace bottle 5 from the central axis after penetrating into the limiting channel 16.

The bottle mouth of the headspace bottle 5 is connected with a bottle cap in a threaded manner, the bottom of the bottle mouth adapter 15 is provided with a connecting groove 17, the inner diameter of the connecting groove 17 is matched with the diameter of the bottle cap of the headspace bottle 5, the bottle cap can be sleeved and stabilized above the headspace bottle 5, the limiting channel 16 is positioned at the center of the bottle mouth, the probe 4 can penetrate into the bottle cap of the headspace bottle 5, and the bottle mouth adapter 15 is sleeved and connected with the headspace bottle 5, so that the bottle cap is more stable and convenient to operate.

The bottle mouth adapter 15 top is offered fixed slot 18, and spacing passageway 16 is offered in the fixed slot 18 bottom, is provided with the introduction director 19 that projects bottleneck adapter 15 top in the fixed slot 18, has offered auxiliary channel 22 in the introduction director 19, and auxiliary channel 22 communicates with each other with spacing passageway 16. By setting the vial mouth adapter 15 to be H-shaped, the top of the vial mouth adapter 15 is provided with a fixing groove 18 for installing the sample introduction guide 19, and the auxiliary channel 22 of the sample introduction guide 19 further adjusts the depth of inserting the contact pin into the headspace bottle 5, and when the probe 4 is inserted, the probe 4 is almost completely positioned in the auxiliary channel 22 and the limiting channel 16 for fixing the probe 4.

The bottom of the hand-held cartridge 20 is detachably inserted into the top of the sample introduction guide 19, and the probe 4 is protruded from the bottom end of the hand-held cartridge 20 and inserted into the auxiliary passage 22. The bottom of the hand-held barrel 20 is detachably embedded in the sample introduction guide 19 for assisting in positioning the hand-held barrel 20 and the handle push rod 14 so as to facilitate the vertical insertion of the probe 4 into the headspace bottle.

The foregoing is merely a preferred embodiment of the present utility model, and it should be noted that modifications and improvements could be made by those skilled in the art without departing from the inventive concept, which falls within the scope of the present utility model.

Claims (8)

1. The utility model provides an manual solid phase microextraction device of integral type, includes workstation (1), workstation (1) are provided with extraction mechanism (2) and ageing mechanism (3), still include probe (4) and headspace bottle (5) that use with extraction mechanism (2) cooperation, inside fibre silk (6) that are provided with of probe (4) bottom are worn out to probe (4) bottom is provided with fibre silk (6) in probe (4) bottom, a serial communication port, ageing mechanism (3) include that the top stretches out ageing passageway (7) that vertically link up of workstation (1) top surface, set up ageing mouth (21) on ageing passageway (7) top and set up in workstation (1) and with ageing passageway (7) bottom intercommunication carrier gas intake pipe (8), be provided with solenoid valve (9) in workstation (1), solenoid valve (9) control connection carrier gas intake pipe (8), in ageing passageway (7) can be inserted from ageing mouth (21), be provided with ageing heater (10) in workstation (1), ageing passageway (10) are connected to ageing heater (10).

2. The integrated manual solid phase microextraction device according to claim 1, wherein the extraction mechanism (2) comprises a plurality of extraction ports (11) embedded at the top of the workbench (1) and a magnetic stirring heating table (12) arranged inside the workbench (1) and connected with the bottom of the extraction ports (11), the top ends of the extraction ports (11) are opened, and the extraction ports (11) are used for inserting and fixing a headspace bottle (5).

3. The integrated manual solid phase microextraction device according to claim 2, wherein an inclined control screen (13) is embedded at the top of the workbench (1), and the control screen (13) is in control connection with the magnetic stirring heating table (12), the aging heater (10) and the electromagnetic valve (9).

4. The integrated manual solid-phase microextraction device according to claim 1, wherein a handle push rod (14) is fixedly arranged at the top of the probe (4), a hand holding cylinder (20) which is slidably connected with the handle push rod is arranged outside the handle push rod (14), the probe (4) can extend out of the bottom end of the hand holding cylinder (20), and the fiber filaments (6) can be vertically inserted into a headspace bottle (5) and fixed on the upper part of the headspace bottle (5).

5. The integrated manual solid-phase microextraction device according to claim 4, wherein a bottleneck adapter (15) is detachably connected to the bottleneck of the headspace bottle (5), a vertically through limiting channel (16) is formed in the middle of the bottleneck adapter (15), and the fiber wires (6) can be inserted into the headspace bottle (5) after passing through the limiting channel (16).

6. The integrated manual solid phase microextraction device according to claim 5, wherein a connecting groove (17) is formed in the bottom of the bottle mouth adapter (15), the inner diameter of the connecting groove (17) is matched with the diameter of the bottle cap of the headspace bottle (5), the bottle mouth adapter (15) can be sleeved with the bottle cap of the headspace bottle (5) and is stabilized above the headspace bottle (5), and the limiting channel (16) is positioned in the center of the bottle mouth.

7. The integrated manual solid-phase microextraction device according to claim 6, wherein a fixing groove (18) is formed in the top of the bottleneck adapter (15), the limiting channel (16) is formed in the bottom of the fixing groove (18), a sample introduction guide (19) protruding out of the top of the bottleneck adapter (15) is arranged in the fixing groove (18), an auxiliary channel (22) is formed in the sample introduction guide (19), and the auxiliary channel (22) is communicated with the limiting channel (16).

8. The integrated manual solid phase microextraction device according to claim 7, wherein the bottom of the hand-held cartridge (20) is detachably inserted into the top of the sample introduction guide (19), and the probe (4) is inserted into the auxiliary channel (22) while extending out of the bottom of the hand-held cartridge (20).

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