CN219070805U - Knot locker and heart valve annular contraction assembly - Google Patents

Abstract

The utility model provides a locking device and a heart valve annular contraction component, and relates to the technical field of medical appliances; the proximal end of the locking wire block is provided with a second limiting extension piece; the wire locking column is arranged in the wire locking block in a penetrating way, the far end of the wire locking column is provided with a threading hole, and the radial cross section of the middle part of the wire locking column is polygonal; the square ring spring is sleeved outside the first limiting extension piece and the second limiting extension piece on the locking wire block to circumferentially restrain the locking wire column; the anti-torsion rod prevents the locking wire block from rotating relative to the anti-torsion rod, the rotating rod rotates relative to the anti-torsion rod, the locking wire column is driven to overcome the elastic force of the square ring spring ring to rotate relative to the locking wire block, and the square ring spring ring always has the movement trend of circumferentially locking the locking wire column on the locking wire block. The utility model relieves the problems of difficult knotting and easy detachment of the mitral valve annuloplasty through the catheter in the prior art, and the problems of high operation difficulty, complex operation and long operation time consumption when the mitral valve regurgitation is treated through the catheter.

Description

Knot locker and heart valve annular contraction assembly

Technical Field

The utility model relates to the technical field of medical equipment, in particular to a knot locker and a heart valve annular contraction assembly.

Background

In surgical treatment, it is often necessary to knot the surgical wire or loop, for example:

the heart valve is a checkpoint between different cardiovascular structures, can only be opened and closed in a certain specific direction, ensures that blood can only flow forward, but can not flow backward, and the mitral valve is a one-way valve between the left atrium and the left ventricle, ensures that blood flows directionally from the left atrium to the left ventricle and flows through a certain blood flow, and blood flows from the left atrium to the left ventricle through the mitral valve, is pumped into the main artery from the left ventricle and flows to the whole body. The mitral valve opens and blood flows from the left atrium into the left ventricle; the mitral valve is then closed, ensuring that when the left ventricle contracts to pump blood to the aorta, blood does not flow back into the left atrium, which would result if the mitral valve were diseased and not sufficiently closed, resulting in regurgitation of blood into the left atrium when the left ventricle contracts, which is mitral regurgitation (mitral regurgitation, MR).

Mitral regurgitation is the most common heart valve disorder worldwide, and it causes a decrease in blood flow to various parts of the body, and in order to compensate, the heart will try to pump blood more forcefully, increasing the heart burden. Patients with severe mitral regurgitation can develop various debilitating symptoms such as shortness of breath, palpitations, dizziness, and fatigue. These patients are at risk of poor quality of life, significantly limited activity, repeated hospitalization for heart failure and increased mortality, and chronic severe mitral regurgitation is often accompanied by heart failure, which can result in death if untreated.

Currently, there are two main approaches to treating mitral insufficiency, namely, medicine and surgical treatment. Clinical studies have shown that drug treatment can only improve symptoms in MR patients, but cannot lengthen patient survival or surgical opportunities. For the serious condition of mitral insufficiency, the need of hemodynamic changes is treated by operation, at present, the mitral regurgitation patient is mainly treated by operation by adopting a transcatheter mitral regurgitation interventional therapy technique, and the mitral regurgitation interventional therapy technique is mainly divided into two categories: one is transcatheter mitral valve repair (transcatheter mitral vakve repair, TMVR), the other is transcatheter mitral valve implantation (transcatheter mitral valve implantation, TMVI), and Transcatheter Mitral Valve Repair (TMVR) mainly comprises (1) transcatheter rim-to-rim "mitral valve" repair, represented by MitraClip; (2) Transcatheter mitral valve annuloplasty (Cardioband), including direct annuloplasty and indirect annuloplasty.

Among them, in catheter mitral annuloplasty (Cardioband), it is necessary to contract, tighten and tie a knot to the soft annulus, and in particular, cardioband is a transcatheter mitral annuloplasty, including direct annuloplasty and indirect annuloplasty. The Cardioband device (Valtech Cardio, orehuda, israel) is a local annuloplasty ring, by venous access, the puncture room space reaches the mitral valve annulus from the left atrium, about 10 rivets are made on the mitral valve annulus of the left atrium, the rivets are connected on a soft ring, the soft ring is tightened by contraction, the effect of ring contraction of the annulus is achieved, and the ring contraction ratio can reach 25% -30%.

The prior art is mainly used for knotting operation wires or wire loops or is used for knotting by relying on the operation skills of doctors through the wire pliers, the visual field of the doctors is limited when knotting, the knotting time is longer than that of the doctors, the operation time is prolonged, and the knotting is unstable due to manual knotting, so that the problem of falling off is likely to occur in the later stage.

In addition, in the Transcatheter Mitral Valve Repair (TMVR) procedure described above:

for a transcatheter rim-to-rim mitral valve repair represented by MitraClip, also called transcatheter mitral valve clamping, under the inspired of a surgical rim-to-rim mitral valve repair technology, a similar technical principle is adopted, a special mitral valve clamp (Clip) is used, the transvascular repair device reaches the heart through a human body, and the middle parts of two leaves of the mitral valve are clamped under three-dimensional ultrasonic guidance, so that the mitral valve is changed from a large single hole to a small double hole in the systole, and mitral regurgitation is reduced, and the following is simple: the device is sent into the heart through the human blood vessel by the catheter mitral valve repair technology, the wound is very small, the heart is not damaged, the heart beats normally in the operation process, the support of extracorporeal cardiopulmonary circulation is not needed, the patient recovers faster, the patient can be discharged after 2-3 days of operation, and the patient can participate in daily activities within 1 week of operation. However, in the prior art, because the size of the mitral valve clamp (Clip) is limited, if the valve leaflet is closed and the joint tissue is small or the distance between the two valves is too far, the two wings of the mitral valve clamp (Clip) cannot capture the two valve cusps simultaneously, and there is not enough valve cusp tissue to fix the clamp, so the application range is limited as in all edge-to-edge repair, the patient needs to be subjected to cardiac ultrasonic examination before operation, and related anatomical standards are satisfied as much as possible, otherwise the problem of operation failure may be caused.

With the catheter mitral annuloplasty (Cardioband) mentioned above, too many nails are required to be driven, and the surgical instrument is difficult to align with the plane of the annulus during actual surgery, so that the operation is difficult and time-consuming.

Thus, in the prior art, when mitral regurgitation is treated by transcatheter mitral valve clamping and transcatheter mitral valve annuloplasty, the problems of high operation difficulty, complex operation and long operation time are common.

Disclosure of Invention

The utility model aims to provide a knot locker and a heart valve annuloplasty assembly, which are used for solving the problems that in the prior art, when mitral regurgitation is treated through a catheter mitral valve annuloplasty, knotting is difficult, knotting is easy to fall off, and the technical problems that when mitral regurgitation is treated through a catheter mitral valve clamp operation and a catheter mitral valve annuloplasty, the operation difficulty is high, the operation is complex and the operation time is long are solved.

In order to achieve the above purpose, the embodiment of the present utility model adopts the following technical scheme:

in a first aspect, an embodiment of the present utility model provides a lock knot apparatus, including a lock wire block, a lock wire post, a square ring spring, an anti-torsion bar, and a rotating rod.

Specifically: the central hole which axially penetrates through the locking line block is formed in the middle of the locking line block, a first limiting extension piece and a second limiting extension piece are arranged at the proximal end of the locking line block, and the first limiting extension piece and the second limiting extension piece are oppositely arranged at two sides of the central hole in the radial direction of the locking line block;

The locking wire column comprises a threading rod section, a rotary positioning rod section and a proximal connecting rod section which are sequentially connected from a distal end to a proximal end; the far end of the threading rod section is provided with a threading hole which radially penetrates through the threading rod section, the radial section of the rotary positioning rod section is polygonal, and the near end of the near end connecting rod section is provided with a first rotary positioning part; the wire locking column is arranged in the central hole of the wire locking block in a penetrating way, the penetrating hole at the far end of the penetrating rod section is exposed out of the wire locking block, the rotary positioning rod section is positioned between the first limiting extension piece and the second limiting extension piece, and the near-end connecting rod section is provided with a first rotary positioning part;

the square ring spring is sleeved outside the first limit extension piece and the second limit extension piece on the locking wire block so as to circumferentially restrict the rotary positioning rod section of the locking wire column;

the far end of the torsion bar is provided with an inserting part;

the far end of the rotating rod is provided with a second rotating positioning part;

the assembly state is as follows:

the grafting portion of preventing the torsion bar is pegged graft in the spacing between first spacing extension piece and the spacing extension piece of second in the circumference of lock line piece to prevent that lock line piece from rotating around the axis of lock line piece relatively, the second rotational positioning portion closure of rotary rod is in the first rotational positioning portion of lock line post, under the circumstances that makes the rotary rod receive relative anti-torsion bar pivoted actuating force, drive the lock line post and overcome the relative lock line piece rotation of elasticity of square ring spring circle, square ring spring circle makes the rotational positioning pole section have the relative lock line piece of circumference all the time and is static in order to lock the motion trend in lock line piece with lock line post circumference.

During operation, the operation wire or the wire loop can pass through the threading hole of the threading rod section in the wire locking column, the wire locking column is penetrated in the central hole of the wire locking block, the threading hole is exposed out of the wire locking block, the rotary positioning rod section is positioned between the first limiting extending piece and the second limiting extending piece, the inserting part of the torsion bar is inserted into the gap between the first limiting extending piece and the second limiting extending piece in the circumferential direction of the wire locking block, and the second rotary positioning part of the rotary rod is locked on the first rotary positioning part of the wire locking column. The anti-torsion bar is fixed through a knot-locking device operation cable in the conveyor, the rotary rod is driven to rotate relative to the anti-torsion bar, thereby the lock wire column is driven to rotate relative to the lock wire block against the elastic force of the square ring spring ring, further the connecting wire is wound on the threading rod section to tighten the operation wire or the wire loop, the square ring spring ring is sleeved outside the first limiting extension piece and the second limiting extension piece on the lock wire block, the rotary positioning rod section of the lock wire column is circumferentially restrained, the square ring spring ring enables the rotary positioning rod section to always have a motion trend of being circumferentially static relative to the lock wire block so as to circumferentially lock the lock wire column in the lock wire block, the rotary rod is stopped, the lock wire column can be circumferentially self-locked in the lock wire block, the lock wire column and the square ring spring ring are left inside a human body after knot tying is completed, and the anti-torsion bar and the rotary rod are withdrawn in the near direction (rear).

The knot locker provided by the embodiment can pull the operation wire or the wire loop in a very short time, is not limited by the visual field of a doctor when knotting, has low requirements on the operation skill and the proficiency of the doctor, is easy to operate, enables the locking wire column to be circumferentially self-locked on the locking wire block by the square ring spring ring after knotting, is not easy to loosen, and can be applied to the mitral regurgitation operation treatment through the catheter mitral annuloplasty without limitation, so that the problems that the knotting is difficult and the knotting is easy to fall off are solved.

In an alternative implementation manner of this embodiment, preferably, a radial section of the rotary positioning rod section is rectangular, and opposite surfaces of the first limiting extension piece and the second limiting extension piece, which face each other, are respectively arc surfaces with a circle center facing the central hole of the lock wire column.

In an alternative implementation manner of this embodiment, it is preferable that the locking wire block includes a distal fixing ring, a proximal fixing ring, and at least two extending ribs; the distal end fixing ring and the proximal end fixing ring are coaxially arranged, and central holes of the proximal end fixing ring and the distal end fixing ring form a central hole of the locking wire block; one end of each of the at least two extending ribs is connected with the far-end fixing ring, the other end of each of the at least two extending ribs is connected with the near-end fixing ring, and a hollowed-out area is formed between the adjacent extending ribs; the first limit extension piece and the second limit extension piece are connected to the proximal end of the proximal end fixing ring and extend towards the proximal direction;

The thread locking column sequentially penetrates through the central holes of the proximal fixing ring and the distal fixing ring from the proximal end to the distal end, and the thread hole at the distal end of the thread rod section is positioned between the proximal fixing ring and the distal fixing ring.

In an optional implementation manner of this embodiment, more preferably, the plugging portion disposed at the distal end of the torsion bar includes at least two plugging rods with proximal ends connected to the proximal end of the torsion bar and extending in a distal direction, and in an assembled state, the plugging rods are plugged in a gap between the first limiting extension piece and the second limiting extension piece in a circumferential direction of the locking wire block, and a side surface of the plugging rod is abutted with a side surface of the first limiting extension piece and a side surface of the second limiting extension piece, so as to prevent the locking wire block from rotating around an axis of the locking wire block relative to the torsion bar.

In an optional implementation manner of this embodiment, more preferably, in the wire locking post, a first buckling groove is provided on a side surface of the proximal connecting rod section, a portion, located on a proximal side of the first buckling groove, on the proximal connecting rod section is a first buckling protrusion, and the first rotation positioning portion includes the first buckling groove and the first buckling protrusion. The second buckling groove is formed in the side face of the distal end of the rotating rod, the second buckling protruding portion is arranged on the rotating rod and located on the side of the distal end of the second buckling groove, and the second rotary positioning portion comprises the second buckling groove and the second buckling protruding portion. The assembly state is as follows: the first buckling convex part is buckled in the second buckling groove, and the second buckling convex part is buckled in the first buckling groove.

In a second aspect, embodiments of the present utility model provide a heart valve annuloplasty assembly comprising two distance-adjusting mechanisms; the two distance-adjusting means each comprise a respective connecting line, two anchor-introducing bases and a locking device according to any of the preceding embodiments.

Wherein: the proximal end of the anchor guiding-in base is provided with an operation cable connecting part, and the anchor guiding-in base is also provided with a limiting part capable of limiting the anchor nail; any adjustable distance mechanism meets the following conditions: one anchor leading-in base is connected with the other anchor leading-in base through a connecting wire, and the connecting wire passes through a threading hole of a threading rod section of a locking string in the locking device; under the assembled state, under the condition that the rotary rod receives relative torsion bar pivoted driving force, drive the lock line post and overcome the relative lock line piece rotation of the elasticity of square ring spring ring, and then make the connecting wire coil in the threading pole section to adjust the effective connection length of connecting wire connection two anchor guide bases.

In addition to the functional effects that the locking device according to the first aspect of the present utility model can achieve, the heart valve annuloplasty assembly according to the present embodiment further includes: the device has the advantages that the device is simple in integral structure, few in structural parts finally left in a patient, compared with a jaw operation and a transcatheter mitral annuloplasty, the device is placed in a manner which does not require surgical instruments to be strictly aligned to an annular plane, is not influenced by joint tissue area and two-valve distance when the valve leaves are closed, can enable the front valve leaf and the rear valve leaf of the mitral valve to be quickly close to achieve the required mitral valve repair effect, is higher in operation efficiency and lower in operation difficulty, is higher in postoperative stability, is more beneficial to the postoperative repair effect of the patient, and fully relieves the problems of high operation difficulty, complex operation and long operation time consumption in the prior art when the mitral valve reflux is treated through the transcatheter mitral annuloplasty and the transcatheter mitral valve clamp operation.

In an alternative implementation of the present embodiment, it is preferable that the heart valve annuloplasty assembly further includes a positioning mechanism configured to assist in positioning the anchor introduction base over the heart valve and assist in driving the anchor into the anchor introduction base in an implanted state, and to withdraw from the patient after implantation is complete; specifically, the positioning mechanism comprises a positioning bracket, wherein the positioning bracket comprises a central connecting piece and four bent elastic legs, the proximal ends of the four elastic legs are fixedly connected to the central connecting piece, the distal ends of the four elastic legs are free ends, and the distal ends of the four elastic legs are positioned at the distal end side of the central connecting piece; the distal ends of the four elastic legs are provided with end connectors, and the end connectors are configured to be capable of being connected to or disconnected from the anchor guide bases of the two adjustable mechanisms in a one-to-one correspondence.

Further preferably, the operation cable connection portion of the anchor introduction base includes a positioning hole provided on a proximal end surface of the anchor introduction base. The end connecting piece of elastic leg free end department includes connecting block and turning connection in the curb plate of connecting block one side, is equipped with the curb plate hole of following curb plate thickness direction and link up the curb plate on the curb plate. In a positioning state, the side plate is attached to the proximal end face of the anchor guiding-in base, and the side plate hole is communicated with the positioning hole on the anchor guiding-in base so that an operation cable of the anchor guiding-in base can pass through the side plate hole, and the anchor guiding-in base can be positioned at the free end of the corresponding elastic leg.

Still further preferably, a limiting protrusion is provided on the proximal end face of the anchor introducing base; with along the thickness direction of curb plate, the curb plate laminating is the distal end of curb plate in the one end of the proximal end face of anchor guide-in base under the locate mode: be equipped with the spacing recess that the proximal direction of orientation curb plate was sunken on the distal end face of curb plate, spacing recess can be under the locate mode with spacing protruding lock, and be equipped with the side notch with spacing recess intercommunication in the radial one end of keeping away from the connecting block of curb plate.

In addition, in an alternative implementation manner of this embodiment, preferably, the anchor guiding-in base includes a tubular main frame body, the limiting portion on the anchor guiding-in base includes a strip-shaped connecting plate and at least two connecting ribs, the strip-shaped connecting plate is connected to one side of the tubular main frame body through the at least two connecting ribs, a hollowed-out portion is formed between two adjacent connecting ribs, and the hollowed-out portion is configured to be capable of being matched with a spiral anchor nail to pass through so as to limit the anchor nail.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present utility model, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of a structure of a latch according to an embodiment of the present utility model;

FIG. 2 is an exploded view of the latch of FIG. 1;

FIG. 3 is a half cross-sectional view of the latch of FIG. 1;

FIG. 4 is a cross-sectional view taken along the direction a-a in FIG. 3;

FIG. 5 is a schematic view of a heart valve annuloplasty assembly according to an embodiment of the present utility model after implantation in a patient with corresponding anchoring studs;

FIG. 6 is a schematic view of the assembled structure of any one of the distance-adjusting mechanisms and its corresponding anchor pin (the final implanted state does not include the illustrated swivel and anti-torsion bars) in the heart valve annuloplasty assembly provided in FIG. 5;

FIG. 7 is a schematic illustration of the positioning mechanism and anchor guide-in base in a positioned state in a heart valve annuloplasty assembly according to an embodiment of the present utility model;

FIG. 8 is a schematic view of the overall structure of the anchor introducing base of FIG. 7;

FIG. 9 is a schematic diagram illustrating a positioning step in a heart valve repair system using a heart valve annuloplasty assembly according to an embodiment of the present utility model;

FIG. 10 is an enlarged view of a portion of the structure of FIG. 9;

FIG. 11 is a schematic illustration of the positioning and locking steps in a heart valve repair system employing a heart valve annuloplasty assembly provided by an embodiment of the present utility model;

FIG. 12 is an enlarged view of a portion of the structure of FIG. 11;

FIG. 13 is an enlarged view of a portion of the structure associated with the anchoring action of the anchor of FIGS. 11 and 12 (including the anchor handling cable not shown in FIGS. 11 and 12);

FIG. 14 is a cross-sectional view of FIG. 13;

FIG. 15 is a schematic view of the steps of withdrawing the positioning mechanism and the conveyor in a heart valve repair system employing a heart valve annuloplasty assembly provided by an embodiment of the present utility model;

FIG. 16 is an enlarged view of a portion of the end connector of the positioning mechanism of FIG. 15;

fig. 17 is an enlarged view of a portion of the anchor guidewire positioning tip of fig. 15.

Icon: 100-anchoring nails; 101-a first distance-adjusting mechanism; 102-a second distance-adjusting mechanism; 11-connecting lines; 12-a knot locker; 121-a lockwire block; 1211-a distal fixation ring; 1212-proximal fixation ring; 1213-extending ribs; 21101-a first limit extension tab; 12102-a second limit extension; 122-locking wire column; 1221-threading a pole segment; 1220-threading hole; 1222-rotating the positioning rod segment; 1223-proximal connecting rod segment; 12231-a first snap groove; 12232-a first snap tab; 123-square ring spring ring; 124-anti-torsion bar; 1241-a plug rod; 125-rotating the rod; 1251-a second snap groove; 1252-second snap-fit protrusions; 13-anchor introduction base; 130-positioning holes; 1301-a tubular main frame body; 131-a limit part; 1311-bar-shaped connection plates; 1312-connecting ribs; 1313-hollowed-out parts; 132-limit protrusions; 2-a positioning mechanism; 21-a central connection; 22-elastic legs; 221-end connector; 2211-connecting block; 2212-side panels; 22120-side plate holes; 22121-a limit groove; 31-an outer tube; 32-an anchor lead-in base operating cable; 321-an anchor guide wire; 3211-positioning the end head; 32111-connecting seats; 32112-columnar heads; 322-positioning a rack operating cable; 33-anchoring the staple operating cable; 34-the latch operating cable.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments of the present utility model. The components of the embodiments of the present utility model generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the utility model, as presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.

In the description of the present utility model, it should be noted that, directions or positional relationships indicated by terms such as "proximal", "distal", "front", "rear", "inner", "outer", etc., are directions or positional relationships based on those shown in the drawings, or are directions or positional relationships conventionally put in use of the inventive product, are merely for convenience of describing the present utility model and simplifying the description, and are not indicative or implying that the apparatus or element to be referred to must have a specific direction, be configured and operated in a specific direction, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and the like, are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance.

In particular, in the utility model, the end of the medical instrument close to the operator is the proximal end of the medical instrument during operation, the end of the medical instrument entering the blood vessel of the patient is the front end of the medical instrument which is the far end of the medical instrument, and the rear end of the medical instrument is the proximal end.

Furthermore, the terms "horizontal," "vertical," and the like do not denote a requirement that the component be absolutely horizontal or overhang, but rather may be slightly inclined. As "horizontal" merely means that its direction is more horizontal than "vertical", and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the present utility model, it should also be noted that, unless explicitly specified and limited otherwise, the terms "disposed," "mounted," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

In particular, from the point of view of cardiac surgery, the anterior and posterior mitral valve leaflet is divided into six areas, A1, A2, A3 anterior leaflet and P1, P2, P3 posterior leaflet, which are standard division modes in the application anatomy of mitral valves in the medical field, and the detailed description of the present utility model is directly incorporated herein.

Some embodiments of the present utility model are described in detail below with reference to the accompanying drawings. The following embodiments and features of the embodiments may be combined with each other without conflict.

Example 1

Referring to fig. 1 to 4, the present embodiment provides a latch 12, the latch 12 including a latch block 121, a latch post 122, a square ring spring 123, a torsion bar 124, and a rotating lever 125.

Specifically, a central hole axially penetrating the locking wire block 121 is formed in the middle of the locking wire block 121, a first limiting extension piece 21101 and a second limiting extension piece 12102 are arranged at the proximal end of the locking wire block 121, and the first limiting extension piece 21101 and the second limiting extension piece 12102 are oppositely arranged on two sides of the central hole in the radial direction of the locking wire block 121. The lock cylinder 122 comprises a threading rod section 1221, a rotary positioning rod section 1222 and a proximal connecting rod section 1223 which are connected in sequence from the distal end to the proximal end; the distal end of the threading rod section 1221 is provided with a threading hole 1220 which radially penetrates through the threading rod section 1221, the radial cross section of the rotary positioning rod section 1222 is polygonal, and the proximal end of the proximal connecting rod section 1223 is provided with a first rotary positioning part; the locking wire post 122 is inserted into the central hole of the locking wire block 121, the threading hole 1220 at the distal end of the threading rod section 1221 exposes the outside of the locking wire block 121, the rotary positioning rod section 1222 is located between the first limit extension piece 21101 and the second limit extension piece 12102, and the proximal connecting rod section 1223 is provided with a first rotary positioning portion. The square ring spring 123 is sleeved outside the first limit extension tab 21101 and the second limit extension tab 12102 on the locking wire block 121 to circumferentially constrain the rotational positioning lever segment 1222 of the locking wire post 122. The distal end of the torsion preventing rod 124 is provided with an inserting part; the distal end of the rotating rod 125 is provided with a second rotational positioning portion.

The assembly state is as follows: the insertion part of the anti-torsion bar 124 is inserted into a gap between the first limit extension piece 21101 and the second limit extension piece 12102 in the circumferential direction of the locking wire block 121, so as to prevent the locking wire block 121 from rotating around the axis of the locking wire block 121 relative to the anti-torsion bar 124, and the second rotation positioning part of the rotating rod 125 is locked to the first rotation positioning part of the locking wire column 122, so that under the condition that the rotating rod 125 is driven to rotate relative to the anti-torsion bar 124, the locking wire column 122 is driven to rotate relative to the locking wire block 121 against the elastic force of the square ring spring 123, and the square ring spring 123 enables the rotation positioning rod section 1222 to always have a movement trend of being stationary relative to the locking wire block 121 in the circumferential direction so as to circumferentially lock the locking wire column 122 to the locking wire block 121.

In operation, the surgical thread or the thread loop may be passed through the threading hole 1220 of the threading rod section 1221 in the thread locking post 122, the thread locking post 122 is threaded into the central hole of the thread locking block 121, the threading hole 1220 is exposed out of the thread locking block 121, the rotation positioning rod section 1222 is located between the first limit extension piece 21101 and the second limit extension piece 12102, the insertion part of the torsion preventing rod 124 is inserted into the gap between the first limit extension piece 21101 and the second limit extension piece 12102 in the circumferential direction of the thread locking block 121, and the second rotation positioning part of the rotation rod 125 is locked to the first rotation positioning part of the thread locking post 122. The anti-torsion bar 124 is fixed by a knot-locking device operation cable in the conveyor, the rotary rod 125 is driven to rotate relative to the anti-torsion bar 124, so that the lock wire column 122 is driven to rotate relative to the lock wire block 121 against the elastic force of the square ring spring ring 123, the connecting wire 11 is wound on the threading rod section 1221 to tighten the operation wire or the wire loop, the square ring spring ring 123 is sleeved outside the first limit extension piece 21101 and the second limit extension piece 12102 on the lock wire block 121, the rotary positioning rod section 1222 of the lock wire column 122 is circumferentially restrained, the square ring spring ring 123 enables the rotary positioning rod section 1222 to always have a motion trend of being circumferentially static relative to the lock wire block 121 to circumferentially lock the lock wire column 122 on the lock wire block 121, the rotary rod 125 is stopped, the lock wire column 122 can be circumferentially locked on the lock wire block 121, the purpose of knot tying is achieved, after the knotting is finished, the anti-torsion bar 124 and the rotary rod 125 are withdrawn in the near direction (backward), and the lock wire column 122 and the square ring spring ring 123 are left inside a human body.

The above-mentioned knot locker provided in this embodiment can pull up the operation wire or the wire loop in a very short time, is not limited by the doctor's visual field when knotting, has low requirements on the doctor's operation skill and proficiency, is easy to operate, and after knotting, the square ring spring 123 makes the wire locking column 122 circumferentially self-lock in the wire locking block 121, is difficult to loosen, can be but not limited to be specifically applied in the operation of treating mitral regurgitation through catheter mitral annuloplasty, and alleviates the problem that it is difficult to knot and is easy to drop.

With continued reference to fig. 1-4, in an alternative implementation of the present embodiment, it is preferable that the radial cross section of the rotary positioning rod segment 1222 is rectangular, and opposite surfaces of the first limiting extension piece 21101 and the second limiting extension piece 12102 facing each other are arc surfaces with a center toward the central hole of the lock cylinder 122.

With continued reference to fig. 1-4, in an alternative implementation of the present embodiment, the locking wire block 121 preferably includes a distal fixation ring 1211, a proximal fixation ring 1212, and at least two extension ribs 1213; the distal end fixing ring 1211 is coaxially arranged with the proximal end fixing ring 1212, and the central holes of the proximal end fixing ring 1212 and the distal end fixing ring 1211 form the central hole of the lockwire block 121; one end of each of the at least two extending ribs 1213 is connected to the distal fixing ring 1211, the other end is connected to the proximal fixing ring 1212, and a hollow area is formed between adjacent extending ribs 1213; the first and second stop extension tabs 21101 and 12102 are connected to the proximal end of the proximal fixation ring 1212 and extend in a proximal direction. The locking post 122 passes through the central holes of the proximal and distal fixation rings 1212 and 1211 in sequence from the proximal end to the distal end, and the threading hole 1220 at the distal end of the threading rod segment 1221 is located between the proximal and distal fixation rings 1212 and 1211.

With continued reference to fig. 1 to 4, in an alternative implementation manner of this embodiment, it is preferable that the plugging portion provided at the distal end of the torsion bar 124 includes at least two plugging rods 1241 having proximal ends connected to the proximal ends of the torsion bar 124 and extending in the distal direction, and in the assembled state, the plugging rods 1241 are plugged into the gaps between the first limiting extension piece 21101 and the second limiting extension piece 12102 in the circumferential direction of the lock wire block 121, and the side surfaces of the plugging rods 1241 abut against the side surfaces of the first limiting extension piece 21101 and the side surfaces of the second limiting extension piece 12102 so as to prevent the lock wire block 121 from rotating around the axis of the lock wire block 121 relative to the torsion bar 124.

With continued reference to fig. 1 to 4, in an alternative implementation manner of the present embodiment, it is preferable that, in the lock wire post 122, a first buckling groove 12231 is provided on a side surface of the proximal connecting rod segment 1223, a portion of the proximal connecting rod segment 1223 located on a proximal side of the first buckling groove 12231 is a first buckling protrusion 12232, and the first rotation positioning portion includes the first buckling groove 12231 and the first buckling protrusion 12232. A second fastening groove 1251 is provided on a distal side of the rotating rod 125, and a second fastening protrusion 1252 is provided on a distal side of the second fastening groove 1251 on the rotating rod 125, and the second rotation positioning portion includes the second fastening groove 1251 and the second fastening protrusion 1252. The assembly state is as follows: the first fastening protrusion 12232 is fastened in the second fastening groove 1251, and the second fastening protrusion 1252 is fastened in the first fastening groove 12231, preferably, in the assembled state, the first rotation positioning portion and the second rotation positioning portion are all located inside the torsion bar 124, so as to restrict the first rotation positioning portion and the second rotation positioning portion by the torsion bar 124, and prevent the two rotation positioning portions from being separated from each other.

Example two

Aiming at the problems of high operation difficulty, complex operation and long operation time consumption in the prior art of treating mitral regurgitation through a catheter mitral valve clamping operation and a catheter mitral valve annuloplasty operation, the embodiment provides a heart valve annuloplasty assembly, and referring to fig. 2 to 17, the heart valve annuloplasty assembly comprises two distance-adjusting mechanisms, namely a first distance-adjusting mechanism 101 and a second distance-adjusting mechanism 102; the two distance-adjusting means each comprise a respective connecting line 11, two anchor-introducing bases 13 and a locking device 12 provided in any of the alternative embodiments of example one, wherein: the proximal end of the anchor introduction base 13 is provided with an operation cable connection portion, and the anchor introduction base 13 is further provided with a stopper portion 131 capable of stopping the anchor 100. Any adjustable distance mechanism meets the following conditions: one anchor introducing base 13 is connected to the other anchor introducing base 13 by a connecting wire 11, and the connecting wire 11 passes through a threading hole 1220 of a threading rod section 1221 of the locking post 122 in the locking device 12; under the assembled state, under the condition that the rotating rod 125 receives the driving force for relatively preventing the torsion bar 124 from rotating, the locking wire post 122 is driven to rotate relative to the locking wire block 121 against the elastic force of the square ring spring ring 123, so that the connecting wire 11 is wound on the threading rod section 1221, and the effective connection length of the connecting wire 11 for connecting the two anchor guiding bases 13 is adjusted.

As shown in fig. 5 and 6, when in use, the two anchor introducing bases 13 of the first distance adjusting mechanism 101 are aligned with the anterior leaflet A1 region and the posterior leaflet P1 region of the mitral valve respectively by using a conveyor, the two anchor introducing bases 13 of the second distance adjusting mechanism 102 are aligned with the anterior leaflet A3 region and the posterior leaflet P3 region of the mitral valve respectively, then the corresponding anchor nails 100 are respectively implanted into the mitral valve along the anchor introducing bases 13 by using the conveyor, and the anchor nails 100 are limited to the limiting parts 131 of the corresponding anchor introducing bases 13 while being implanted into the mitral valve; then, the conveyor is used to respectively control the locking device 12 of the first distance adjusting mechanism 101 and the locking device 12 of the second distance adjusting mechanism 102, so as to shorten the effective connection length of the connecting wires 11 of the two distance adjusting mechanisms for connecting the two anchor guiding bases 13, and further enable the anterior leaflet and the posterior leaflet of the mitral valve to be quickly close to each other, thereby achieving the required mitral valve repair effect. In any distance-adjusting mechanism, the connecting wire 11 is preferably an annular wire which sequentially passes through a threading hole 1220 on the threading rod section 1221 of one anchor leading-in base 13 and the locking wire post 122 and is connected end to end after the other anchor leading-in base 13; the latch operating cable at least comprises a cable fixedly connected or integrally connected to the proximal end of the rotating rod 125 and a cable fixedly connected or integrally connected to the distal end of the anti-torsion rod 124, the anti-torsion rod 124 is controlled by two cables to keep the latch wire block 121 unable to rotate around the axis thereof, and the rotating rod 125 is rotated relative to the anti-torsion rod 124, so that the latch wire block 122 can be driven to rotate relative to the latch wire block 121 against the elastic force of the square ring spring 123, the connecting wire 11 is wound on the threading rod section 1221 to tighten the surgical wire or the wire loop, the square ring spring 123 is sleeved outside the first limit extension piece 21101 and the second limit extension piece 12102 on the latch wire block 121, the rotary positioning rod section 1222 of the latch wire block 122 is circumferentially restrained, and the square ring spring 123 makes the rotary positioning rod section 1222 always have a motion trend of being circumferentially static relative to the latch wire block 121 to lock the latch wire block 122, thereby stopping rotating the rotating rod 125, the latch wire block 122 can be circumferentially self-locked to the latch wire block 121, after knotting is completed, the latch wire is retracted proximally (back) from the anti-torsion rod 121 and the torsion rod 122, and the human body 122 can be left inside the latch wire block 122.

Referring to fig. 5 and 6, in addition to the functional effects that can be achieved by the locking device provided in the first embodiment, the above-mentioned heart valve annuloplasty assembly provided in this embodiment further includes: the device has the advantages that the device is simple in integral structure, few in structural parts finally left in a patient, compared with a jaw operation and a transcatheter mitral annuloplasty, the device is placed in a manner which does not require surgical instruments to be strictly aligned to an annular plane, is not influenced by joint tissue area and two-valve distance when the valve leaves are closed, can enable the front valve leaf and the rear valve leaf of the mitral valve to be quickly close to achieve the required mitral valve repair effect, is higher in operation efficiency and lower in operation difficulty, is higher in postoperative stability, is more beneficial to the postoperative repair effect of the patient, and fully relieves the problems of high operation difficulty, complex operation and long operation time consumption in the prior art when the mitral valve reflux is treated through the transcatheter mitral annuloplasty and the transcatheter mitral valve clamp operation.

In this embodiment, when the above-mentioned heart valve annuloplasty assembly is implanted in a patient by using a conveyor, there are various specific alignment manners of aligning the two anchor introducing bases 13 of the above-mentioned first distance adjusting mechanism 101 with the anterior leaflet A1 region of the mitral valve and the posterior leaflet P1 region of the mitral valve, and aligning the two anchor introducing bases 13 of the second distance adjusting mechanism 102 with the anterior leaflet A3 region of the mitral valve and the posterior leaflet P3 region of the mitral valve, for example, but not limited to, adjusting each anchor introducing base 13 in a one-to-one correspondence manner by using a developing device and a plurality of operation cables, respectively, etc., however, in order to ensure the high efficiency of the operation process, referring to fig. 7, in combination with fig. 10 to 15, in a plurality of alternative embodiments of this embodiment, it is preferable that the above-mentioned heart valve annuloplasty assembly further includes a positioning mechanism 2, the positioning mechanism 2 is configured to be able to position the auxiliary anchor introducing base 13 on the heart and the auxiliary anchor introducing base 13 into the corresponding anchor introducing base 13 in an implantation state, and to be able to be withdrawn from the patient after the implantation is completed; as shown in fig. 7, the positioning mechanism 2 includes a positioning bracket, specifically, the positioning bracket includes a central connecting member 21 and four curved elastic legs 22, proximal ends of the four elastic legs 22 are fixedly connected to the central connecting member 21, distal ends of the four elastic legs 22 are free ends, and distal ends of the four elastic legs 22 are located on a distal side of the central connecting member 21; an end connector 221 is provided at the distal ends of each of the four elastic legs 22, and the end connectors 221 are configured to be capable of being connected to and disconnected from the respective anchor introduction bases 13 of the two distance-adjusting mechanisms one by one.

Before the heart valve annular contraction component is implanted into a patient by using a conveyor, end connecting pieces 221 of each of four elastic legs 22 of the positioning bracket are connected to anchor guide-in bases 13 of two distance-adjusting mechanisms in a one-to-one correspondence manner, and relative intervals of the four anchor guide-in bases 13 are limited by using the positioning bracket, so that the four anchor guide-in bases 13 are respectively and quickly aligned with four areas A1, A3, P1 and P3 of the mitral valve; after the anchor nails 100 are correspondingly implanted, the end connecting pieces 221 of the four elastic legs 22 of the positioning support are separated from the anchor nails of the two distance-adjusting mechanisms in a one-to-one correspondence manner by using the conveyor, the positioning support is withdrawn after being guided into the base 13, and finally the positioning support leaves the patient, so that the number of structural parts reserved in the patient is ensured to be as small as possible, and the volume is small.

In the above preferred embodiment, it is further preferred, but not limited to, that the operation cable connection portion of the anchor introduction base 13 includes a positioning hole 130 provided on the proximal end surface of the anchor introduction base 13 as shown in fig. 8, 10 and 13 to 17; the end connection piece 221 at the free end of the elastic leg 22 includes a connection block 2211 and a side plate 2212 connected at a corner to one side of the connection block 2211, and a side plate hole 22120 penetrating the side plate 2212 in the thickness direction of the side plate 2212 is provided in the side plate 2212. In the positioning state, the side plate 2212 is attached to the proximal end surface of the anchor guiding-in base 13, and the side plate hole 22120 is communicated with the positioning hole 130 on the anchor guiding-in base 13, so that an operation cable of the anchor guiding-in base 13 passes through, and the anchor guiding-in base 13 is positioned at the free end of the corresponding elastic leg 22. When the end connectors 221 of the four elastic legs 22 of the positioning bracket are required to be separated from the anchor guide bases 13 of the two distance-adjusting mechanisms in a one-to-one correspondence manner, the operation cables of the corresponding anchor guide bases 13 are withdrawn in the proximal direction (backward), at this time, the end connectors 221 of the four elastic legs 22 can be separated from the anchor guide bases 13 and the anchor nails 100 under the self-elasticity of the elastic legs, and then the cables of the operation conveyor are withdrawn to the positioning bracket.

In addition, referring to fig. 8 and 14, in a further preferred embodiment, a stopper protrusion 132 is provided on the proximal surface of the anchor introducing base 13; referring to fig. 14 and 16, in order to follow the thickness direction of the side plate 2212 at the free end of the elastic leg 22, the end of the side plate 2212 which is fitted to the proximal end face of the anchor introducing base 13 in the positioned state is the distal end of the side plate 2212: the distal end surface of the side plate 2212 is provided with a limit groove 22121 recessed toward the proximal direction of the side plate 2212, the limit groove 22121 can be buckled with the limit protrusion 132 in a positioning state, and one end of the side plate 2212, which is far away from the connecting block 2211 in the radial direction, is provided with a side notch communicated with the limit groove 22121. By arranging the limiting protrusion 132 and the limiting groove 22121, the side plate 2212 at the free end of the elastic leg 22 and the anchor guiding-in base 13 can be positioned in the circumferential direction, so that the elastic leg 22 and the anchor guiding-in base 13 are prevented from rotating in the circumferential direction when the anchor 100 is implanted, and the normal implantation of the anchor 100 is prevented.

In the preferred embodiment, the anchor pin 100 is implanted in various ways, for example, but not limited to, referring to fig. 13 and 14, and referring to fig. 7 and 8, the anchor introducing base 13 includes a tubular main frame body 1301, the limiting portion 131 on the anchor introducing base 13 includes a strip-shaped connecting plate 1311 and at least two connecting ribs 1312, the strip-shaped connecting plate 1311 is connected to one side of the tubular main frame body 1301 through the at least two connecting ribs 1312, a hollowed portion 1313 is formed between two adjacent connecting ribs 1312, and the hollowed portion 1313 is configured to be capable of passing through in cooperation with the spiral anchor pin 100 so as to limit the anchor pin 100; that is, when the operation cable of the anchor introducing base 13 is passed through the side plate hole 22120 of the side plate 2212 at the free end of the elastic leg 22 and the positioning hole 130 of the anchor introducing base 13, the anchor introducing base 13 is connected to the free end of the elastic leg 22, and at this time, the anchor 100 is rotated around the anchor introducing base 13 by operating the cable connected to the proximal end of the anchor 100 to rotate the anchor 100, the spiral section of the anchor 100 is wound around the hollowed-out portion 1313, so that the corresponding anchor introducing base 13 is anchored to the corresponding region of the valve.

For a heart valve repair system to which the above-described heart valve annuloplasty assembly is applied, its matable conveyor structure, referring to fig. 9-15, includes an outer tube 31, an anchor introduction base operating cable 32, an anchor pin operating cable 33, and a latch operating cable 34; the anchor introduction base operating cable 32, the anchor operating cable 33, and the latch operating cable 34 all pass through the outer tube 31; a multi-lumen tube may be provided inside the outer tube 31, but is not limited to, to pass through each operation cable, and to prevent each operation cable from interfering with each other.

The latch operating cable 34 preferably includes an outer sheath, a rotating rod operating cable integrally or fixedly connected to the proximal end of the rotating rod 125, and a torsion bar operating cable integrally or fixedly connected to the proximal end of the torsion bar 124, both of which pass through the inside of the outer sheath to control the latch 12 to adjust the effective connection length of the corresponding connection wire 11.

The anchor introducing base operation cable 32 is configured such that a distal end is detachably connected to an operation cable connection portion of the anchor introducing base 13; the anchor pin manipulation cable 33 is configured such that a distal end is detachably connected to the manipulation cable connection portion of the anchor pin 100 to control the rotation of the anchor pin 100 around the corresponding anchor pin introduction base 13, thereby allowing the use of the anchor pin to be stopped or separated from the stopper portion 131 of the corresponding anchor pin introduction base 13.

In more detail, with continued reference to fig. 9 to 15, in some alternative implementations provided in this embodiment, in the above-mentioned structure including the positioning mechanism 2, and in the positioned state, the side plate 2212 at the free end of the elastic leg 22 is attached to the proximal end surface of the anchor introducing base 13, and the side plate hole 22120 is in communication with the positioning hole 130 on the anchor introducing base 13, so as to allow the operation cable of the anchor introducing base 13 to pass therethrough, thereby positioning the anchor introducing base 13 at the specific implementation structure of the free end of the corresponding elastic leg 22, and further, as shown in fig. 12, the aforementioned anchor introducing base operation cable 32 includes an anchor guide wire 321 and a positioning bracket operation cable 322; referring to fig. 13 and 14 and the other figures of fig. 9-17, the anchor wire 321 passes through the corresponding axial perforations in the anchor 100, the side plate holes 22120 at the distal ends of the resilient legs 22, and the locating holes 130 at the distal ends of the anchor introduction base 13 in sequence from the proximal end to the distal end; the distal end of the anchor guide wire 321 is provided with a positioning end head 3211, and the positioning end head 3211 comprises a connecting seat 32111 and a columnar head 32112 which are sequentially connected from the proximal end to the distal end of the anchor guide wire 321; the columnar heads 32112 penetrate through the side plate holes 22120 and are inserted into the positioning holes 130 of the anchor guide bases 13, the connecting seats 32111 are limited at the proximal end sides of the side plates 2212, the anchor guide bases 13 are positioned at the free ends of the corresponding elastic legs 22 under the penetrating positioning of the anchor guide wires 321, the anchor operation cables 33 are sleeved outside the anchor guide wires 321, when the anchor operation cables 33 are rotated, the anchor nails 100 can be rotationally implanted into the corresponding heart valve areas around the anchor guide bases 13, and meanwhile, the anchor nails 100 are limited at the anchor guide bases 13 to position the anchor guide bases 13; the distal end of the positioning bracket operating cable 322 is detachably connected to the center connector 21 of the positioning bracket by a screw connection or a male-female positioning connection, and in the connected state, both distance adjusting mechanisms are pushed out by pushing the positioning bracket operating cable 322 forward.

In addition, in the present embodiment, for the positioning head 3211, it is preferable, but not limited to, that the distal end surface of the connecting seat 32111 is a tapered surface with a diameter gradually decreasing from the proximal end to the distal end, and the distal end surface of the tapered surface is an abutment surface; in addition, the outer peripheral surface of the columnar head 32112 of the positioning head 3211 and the hole wall of the positioning hole 130 of the anchor guiding-in base 13 which is correspondingly inserted can be connected through threads, and in the concrete operation, the connection positioning and the separation operation are realized through the anchor nail operation cable 33.

Finally, it should be noted that: in the present specification, each embodiment is described in a progressive manner, and each embodiment is mainly described by differences from other embodiments, and identical and similar parts between the embodiments are only required to be seen with each other; the above embodiments in the present specification are only for illustrating the technical solution of the present utility model, and are not limiting; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the utility model.

Claims (10)

1. A knot locker (12) is characterized by comprising a locking wire block (121), a locking wire post (122), a square ring spring ring (123), an anti-torsion rod (124) and a rotating rod (125);

the middle part of the locking line block (121) is provided with a central hole which axially penetrates through the locking line block (121), the near end of the locking line block (121) is provided with a first limit extension piece (21101) and a second limit extension piece (12102), and the first limit extension piece (21101) and the second limit extension piece (12102) are oppositely arranged at two sides of the central hole in the radial direction of the locking line block (121);

the locking wire post (122) comprises a threading rod section (1221), a rotary positioning rod section (1222) and a proximal connecting rod section (1223) which are sequentially connected from the distal end to the proximal end; the far end of the threading rod section (1221) is provided with a threading hole (1220) which radially penetrates through the threading rod section (1221), the radial cross section of the rotary positioning rod section (1222) is polygonal, and the near end of the near end connecting rod section (1223) is provided with a first rotary positioning part; the locking wire column (122) is arranged in a central hole of the locking wire block (121) in a penetrating way, a threading hole (1220) at the far end of the threading rod section (1221) is exposed out of the locking wire block (121), the rotary positioning rod section (1222) is positioned between the first limit extension piece (21101) and the second limit extension piece (12102), and the near-end connecting rod section (1223) is provided with a first rotary positioning part;

The square ring spring ring (123) is sleeved outside the first limit extension piece (21101) and the second limit extension piece (12102) on the locking wire block (121) so as to circumferentially restrict the rotary positioning rod section (1222) of the locking wire post (122);

the far end of the anti-torsion rod (124) is provided with an inserting part;

the distal end of the rotating rod (125) is provided with a second rotating positioning part;

the assembly state is as follows:

the plug-in part of the anti-torsion bar (124) is plugged into a gap between a first limit extension piece (21101) and a second limit extension piece (12102) in the circumferential direction of the locking wire block (121), so that the locking wire block (121) is prevented from rotating around the axis of the locking wire block (121) relative to the anti-torsion bar (124), the second rotary positioning part of the rotary bar (125) is locked at the first rotary positioning part of the locking wire post (122), and the locking wire post (122) is driven to rotate relative to the locking wire block (121) under the condition that the rotary bar (125) is subjected to a driving force rotating relative to the anti-torsion bar (124), the elastic force of the square ring spring ring (123) is overcome, and the square ring spring ring (123) enables the rotary positioning bar segment (1222) to be always static relative to the locking wire block (121) in the circumferential direction so as to lock the movement trend of the locking wire post (122) in the circumferential direction of the locking wire block (121).

2. The knot-locker (12) of claim 1, wherein the radial cross-section of the rotary positioning rod segment (1222) is rectangular, and the facing surfaces of the first limit extension piece (21101) and the second limit extension piece (12102) facing each other are respectively circular arc surfaces with the center facing the central hole of the locking thread post (122).

3. The knot-locker (12) of claim 1, wherein: the locking wire block (121) comprises a far-end fixing ring (1211), a near-end fixing ring (1212) and at least two extending ribs (1213); the distal end fixing ring (1211) is coaxially arranged with the proximal end fixing ring (1212), and the central holes of the proximal end fixing ring (1212) and the distal end fixing ring (1211) form a central hole of a locking wire block (121); one end of each of the at least two extending ribs (1213) is connected to the distal fixing ring (1211) and the other end is connected to the proximal fixing ring (1212), and a hollow area is formed between adjacent extending ribs (1213); the first limit extension tab (21101) and the second limit extension tab (12102) are connected to the proximal end of the proximal fixation ring (1212) and extend in a proximal direction;

the locking wire post (122) sequentially penetrates through the central holes of the proximal end fixing ring (1212) and the distal end fixing ring (1211) from the proximal end to the distal end, and the threading hole (1220) at the distal end of the threading rod section (1221) is positioned between the proximal end fixing ring (1212) and the distal end fixing ring (1211).

4. The knot-locker (12) of claim 1, wherein: the plug-in part arranged at the far end of the torsion bar (124) comprises at least two plug-in rods (1241) with the near ends connected with the near ends of the torsion bar (124) and extending towards the far end direction, in the assembled state, the plug-in rods (1241) are plugged in gaps between a first spacing extending piece (21101) and a second spacing extending piece (12102) in the circumferential direction of the locking wire block (121), and the side surfaces of the plug-in rods (1241) are abutted with the side surfaces of the first spacing extending piece (21101) and the side surfaces of the second spacing extending piece (12102) so as to prevent the locking wire block (121) from rotating around the axis of the locking wire block (121) relative to the torsion bar (124).

5. The knot-locker (12) of claim 1, wherein: in the locking wire post (122), a first buckling groove (12231) is formed in the side surface of the proximal connecting rod section (1223), a first buckling protruding part (12232) is formed on the proximal connecting rod section (1223) at a position located on the proximal side of the first buckling groove (12231), and the first rotation positioning part comprises the first buckling groove (12231) and the first buckling protruding part (12232);

a second buckling groove (1251) is formed in the side surface of the distal end of the rotating rod (125), a second buckling protruding part (1252) is arranged on the rotating rod (125) and positioned on the distal end side of the second buckling groove (1251), and the second rotation positioning part comprises the second buckling groove (1251) and the second buckling protruding part (1252);

The assembly state is as follows: the first buckling protruding portion (12232) is buckled in the second buckling groove (1251), and the second buckling protruding portion (1252) is buckled in the first buckling groove (12231).

6. A heart valve annuloplasty assembly, characterized by: comprises two distance-adjusting mechanisms;

the two distance-adjusting means each comprise a respective connecting line (11), two anchor-introducing bases (13) and a locking device (12) according to any one of claims 1 to 5, wherein: an operation cable connecting part is arranged at the proximal end of the anchor guiding-in base (13), and a limiting part (131) capable of limiting the anchor (100) is further arranged on the anchor guiding-in base (13);

any adjustable distance mechanism meets the following conditions:

one anchor introducing base (13) is connected to the other anchor introducing base (13) through a connecting wire (11), and the connecting wire (11) passes through a threading hole (1220) of a threading rod section (1221) of a locking string (122) in the locking device (12); under the assembled state, under the condition that the rotary rod (125) receives the driving force which rotates relative to the anti-torsion rod (124), the locking wire post (122) is driven to overcome the elastic force of the square ring spring ring (123) to rotate relative to the locking wire block (121), so that the connecting wire (11) is wound on the threading rod section (1221), and the effective connection length of the connecting wire (11) for connecting two anchor nail leading-in bases (13) is adjusted.

7. The heart valve annuli assembly of claim 6, wherein: the heart valve annuloplasty assembly further comprises a positioning mechanism (2);

the positioning mechanism (2) is configured to assist the anchor introduction base (13) to position on a heart valve and assist the anchor nails (100) to be driven into the anchor introduction base (13) in an implanted state, and to withdraw from the patient after implantation is completed;

the positioning mechanism (2) comprises a positioning bracket, wherein the positioning bracket comprises a central connecting piece (21) and four bent elastic legs (22), the proximal ends of the four elastic legs (22) are fixedly connected to the central connecting piece (21), the distal ends of the four elastic legs (22) are free ends, and the distal ends of the four elastic legs (22) are positioned on the distal end side of the central connecting piece (21);

the distal ends of the four elastic legs (22) are respectively provided with an end connecting piece (221), and the end connecting pieces (221) are configured to be connected with or disconnected from the anchor guiding bases (13) of the two adjustable mechanisms in a one-to-one correspondence.

8. The heart valve annuli assembly of claim 7, wherein:

the operation cable connecting part of the anchor guiding-in base (13) comprises a positioning hole (130) arranged on the proximal end surface of the anchor guiding-in base (13);

The end connecting piece (221) at the free end of the elastic leg (22) comprises a connecting block (2211) and a side plate (2212) with a corner connected to one side of the connecting block (2211), wherein a side plate hole (22120) penetrating through the side plate (2212) along the thickness direction of the side plate (2212) is formed in the side plate (2212);

in a positioning state, the side plate (2212) is attached to the proximal end face of the anchor guiding-in base (13), the side plate hole (22120) is communicated with the positioning hole (130) on the anchor guiding-in base (13) so that an operation cable of the anchor guiding-in base (13) can pass through, and the anchor guiding-in base (13) is positioned at the free end of the corresponding elastic leg (22).

9. The heart valve annuli assembly of claim 8, wherein:

a limit protrusion (132) is arranged on the proximal end surface of the anchor guiding base (13);

in order to follow the thickness direction of the curb plate (2212), the one end of the curb plate (2212) which is attached to the proximal end surface of the anchor introducing base (13) in the positioning state is the distal end of the curb plate (2212):

the distal end face of the side plate (2212) is provided with a limiting groove (22121) recessed towards the proximal direction of the side plate (2212), the limiting groove (22121) can be buckled with the limiting protrusion (132) in a positioning state, and one end, away from the connecting block (2211) in the radial direction, of the side plate (2212) is provided with a side notch communicated with the limiting groove (22121).

10. The heart valve annuloplasty assembly of any of claims 6-9, wherein: the anchor guiding-in base (13) comprises a tubular main frame body (1301), a limiting part (131) on the anchor guiding-in base (13) comprises a strip-shaped connecting plate (1311) and at least two connecting ribs (1312), the strip-shaped connecting plate (1311) is connected to one side of the tubular main frame body (1301) through the at least two connecting ribs (1312), a hollowed-out part (1313) is formed between every two adjacent connecting ribs (1312), and the hollowed-out part (1313) is configured to be capable of being matched with a spiral anchoring nail (100) to penetrate so as to limit the anchoring nail (100).

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