CN219070527U

CN219070527U - Ultrasonic ablation device

Info

Publication number: CN219070527U
Application number: CN202222621010.XU
Authority: CN
Inventors: 苏浩波; 马骏; 李国强; 邹沛倩
Original assignee: Cuijie Medical Technology Nanjing Co ltd
Current assignee: Cuijie Medical Technology Nanjing Co ltd
Priority date: 2022-09-30
Filing date: 2022-09-30
Publication date: 2023-05-26
Anticipated expiration: 2032-09-30

Abstract

The utility model discloses an ultrasonic ablation device, which comprises an ultrasonic host machine and an operating handle connected with the ultrasonic host machine, wherein a catheter is arranged on the operating handle, and a cooling liquid cavity, an ablation cavity and a plurality of medicine introducing cavities are arranged in the catheter; an ultrasonic signal generator is arranged in the end part of the ablation cavity and is connected with an ultrasonic host through a transistor; the catheter is provided with a plurality of groups of side holes which are communicated with the drug introducing cavity, the catheter is provided with a cooling liquid cavity and the drug introducing cavity, the cooling liquid flowing in the cooling liquid cavity can achieve the purpose of cooling blood vessels, damage to inner blood vessels can be avoided to a great extent, sedative and analgesic drugs can be injected through the drug introducing cavity, pain of patients is relieved, and the catheter is beneficial to operation.

Description

Ultrasonic ablation device

Technical Field

The utility model relates to the field of medical equipment, in particular to an ultrasonic ablation device.

Background

The blood pressure of most patients with hypertension can be controlled at a satisfactory level after the patients with hypertension are treated by antihypertensive drugs, wherein 15-20% of patients with hypertension are treated by using three antihypertensive drugs which are combined reasonably and in sufficient quantity on the basis of improving life style, and the blood pressure is still above a target level or at least 4 antihypertensive drugs are required to reach the standard, so that the patients with hypertension are called refractory hypertension. The current treatment modes for refractory hypertension mainly comprise non-drug treatment, drug treatment and some other treatment modes;

transcatheter renal denervation (renal denervation) is a hot topic in the field of hypertension in recent years. There are both afferent and efferent fibers of the sympathetic nerve on the kidneys. RDN hypotension is closely related to the physiological effects of these nerves. Sympathetic efferent fibers refer to spinal cord to renal sympathetic nerves, the actions of which can be summarized simply as constricting renal blood vessels, enhancing sodium reabsorption from renal tubules and increasing glomerular cell renin secretion, each of which is associated with elevated blood pressure. Sympathetic afferent fibers refer to the sympathetic nerves of the kidney to the spinal cord. Previous studies have found that removal of afferent fibers not only reduces afferent sympathetic signals, but also produces a special effect in the neurological field, inverse transsynaptic, long term, mediating brain stem and stellate ganglion remodeling, leading to reduced systemic sympathetic activity, and reduces other sympathologically activated side effects (such as tachyarrhythmia) in addition to lowering blood pressure. RDN surgery may be performed to remove both sympathetic afferent and afferent fibers, and to increase sodium excretion. The activity of the RAS system is reduced, and the whole body sympathetic tone can also be reduced, so that the effects of reducing blood pressure are achieved;

current rf technology has been used in RDN procedures, where 4 sets of electrodes, represented by Symplicity Spyral, are mounted on the tip to simultaneously ablate 4 sites in a spiral pattern. The device is improved compared with the previous generations, the surgical mode is also improved, the distal end and branches of the main trunk of the renal artery are also included in the ablation range, the renal artery edema and/or spasm can be caused by radiofrequency ablation, the renal artery edema and/or spasm can be relieved by using nitroglycerin or verapamil through the artery, in addition, research shows that the radiofrequency ablation energy can cause transient endothelial abscission, cell swelling, tissue coagulation and embolism formation, and ultrasound is gradually applied to the field at present, so that an ultrasound ablation device is required to be designed.

Disclosure of Invention

The present utility model provides an ultrasound ablation device that solves at least one of the problems identified in the background.

An ultrasonic ablation device comprises an ultrasonic host machine and an operating handle connected with the ultrasonic host machine, wherein a catheter is arranged on the operating handle, and a cooling liquid cavity, an ablation cavity and a plurality of medicine introducing cavities are arranged in the catheter;

the ablation cavity is positioned in the cooling liquid cavity, and a plurality of medicine introducing cavities are distributed on the outer side of the cooling liquid cavity;

an ultrasonic signal generator is arranged in the end part of the ablation cavity and is connected with an ultrasonic host through a transistor;

the catheter is provided with a plurality of groups of side holes on the part corresponding to the ultrasonic signal generator, and the side holes are communicated with the medicine introducing cavity.

Preferably, the operating handle comprises a shell, a cooling liquid bin and a medicine bin, wherein the cooling liquid bin and the medicine bin are arranged in the shell, the cooling liquid bin is communicated with the cooling liquid cavity, and the medicine bin is communicated with the medicine introducing cavity;

and the operating handle is also provided with a cooling liquid pipe and a drug administration pipe which are respectively communicated with the cooling liquid bin and the drug bin.

Preferably, the cooling liquid cavity comprises a circular channel and a plurality of convex parts which extend along the radial direction and are circumferentially distributed, and any one of the medicine introducing cavities is positioned between two adjacent convex parts.

Preferably, the transistor is provided with two developing points, and the two developing points are respectively positioned at two sides of the ultrasonic signal generator.

Preferably, the catheter is sleeved with an insulating sleeve, and through holes are formed in positions, corresponding to the side holes, of the insulating sleeve.

Compared with the prior art, the utility model has the beneficial effects that: compared with the radio frequency RDN ablation in the prior art, the ultrasonic RDN ablation has the advantages that the ultrasonic penetration is stronger, the ablation effect is more excellent, renal artery branch ablation is not needed, an ultrasonic ablation catheter is not directly contacted with the blood vessel wall, the damage to the blood vessel wall is minimum, the ultrasonic ablation catheter can be used for a blood vessel after stent implantation, the ultrasonic ablation catheter is a cylindrical piezoelectric crystal and is vibrated at high frequency after being electrified, circumferential ultrasonic waves can be generated, surrounding tissues receive the ultrasonic waves and heat after the ultrasonic waves are generated, so that the purpose of ablation is achieved, in addition, the purpose of cooling the blood vessel can be achieved by cooling liquid flowing in the catheter, and damage to an inner-layer blood vessel can be avoided to a great extent.

Drawings

FIG. 1 is a schematic diagram of the structure of the present utility model;

FIG. 2 is a schematic view of the handle and catheter of the present utility model;

FIG. 3 is a schematic view of the structure of a portion of the catheter of the present utility model with a side hole;

FIG. 4 is a cross-sectional view of a catheter of the present utility model;

FIG. 5 is a schematic view of the handle of the present utility model;

FIG. 6 is a schematic view of the internal structure of the handle of the present utility model;

FIG. 7 is a schematic view showing the internal structure of the cooling liquid bin of the utility model;

FIG. 8 is a schematic view of the internal structure of the drug cartridge of the present utility model;

fig. 9 is a partial cross-sectional view of a catheter of the present utility model.

Reference numerals illustrate:

1-ultrasonic host, 2-operating handle, 3-pipe, 4-coolant cavity, 41-circular channel, 42-convex part, 5-ablation chamber, 6-medicine introducing chamber, 7-ultrasonic signal generator, 8-transistor, 9-side opening, 10-developing point, 11-casing, 12-coolant bin, 13-medicine bin, 14-coolant tube, 15-administration tube, 16-insulating sleeve, 17-through hole.

Detailed Description

One embodiment of the present utility model will be described in detail below with reference to the attached drawings, but it should be understood that the scope of the present utility model is not limited by the embodiment.

As shown in fig. 1 to 9, an ultrasonic ablation device provided by the embodiment of the utility model includes an ultrasonic host 1 and an operation handle 2 connected with the ultrasonic host 1, the ultrasonic host 1 is not described herein in detail for the prior art, as shown in fig. 1, the operation handle 2 is connected with the ultrasonic host 1 through a connecting pipe, a transistor 8 is located in the connecting pipe, a catheter 3 is arranged on the operation handle 2, and a cooling liquid cavity 4, an ablation cavity 5 and a plurality of drug introducing cavities 6 are arranged in the catheter 3;

the ablation cavity 5 is located in the cooling liquid cavity 4, and a plurality of medicine introducing cavities 6 are distributed on the outer side of the cooling liquid cavity 4, specifically, as shown in fig. 4, the number of medicine introducing cavities 6 in the embodiment is 3;

as shown in fig. 9, an ultrasonic signal generator 7 is disposed in an end portion of the ablation cavity 5 (the end portion refers to the end of the two ends of the ablation cavity 5 away from the operating handle 2, that is, the end shown in fig. 3), the ultrasonic signal generator 7 is connected with the ultrasonic host 1 through a transistor 8, the ultrasonic RDN fusion technology is the prior art, and the principle is not repeated;

as shown in fig. 3, 4 and 9, a plurality of groups of side holes 9 are formed in the part of the catheter 3 corresponding to the ultrasonic signal generator 7, the side holes 9 are communicated with the medicine introducing cavity 6, and the transistor 8 and the ultrasonic signal generator 7 are hidden in the medicine introducing cavity 6 in fig. 4;

the catheter 3 is sleeved with an insulating sleeve 16, and through holes 17 are formed in the positions of the insulating sleeve 16 corresponding to the side holes 9;

as shown in fig. 5 to 8, the operating handle 2 comprises a shell 11, and a cooling liquid bin 12 and a medicine bin 13 which are arranged in the shell 11, wherein the cooling liquid bin 12 is communicated with the cooling liquid cavity 4, and the medicine bin 13 is communicated with the medicine introducing cavity 6; in fig. 8, the medicine compartment 13 is hidden, and it can be seen from fig. 8 that the catheter 3 is provided with a through groove for communicating the medicine compartment 13 with the medicine introducing cavity 6;

as can be seen from fig. 5, the opening of the ablation chamber 5 is located in the operating handle 2 (outside the cooling liquid bin 12), a yielding groove is formed in the housing 11, and the transistor 8 (the transistor 8 may also be referred to as a signal connection line) also passes through the yielding groove, and the guide wire can extend into the ablation chamber 5 through the yielding groove, so that the position of the catheter 3 in the blood vessel can be conveniently adjusted;

the end cap of the operating handle 2 is hidden in fig. 5;

as shown in fig. 6, the operating handle 2 is also provided with a cooling liquid pipe 14 and a drug delivery pipe 15 which are respectively communicated with the cooling liquid bin 12 and the drug bin 13;

the cooling liquid can be injected into the cooling liquid cavity 4 through the cooling liquid pipe 14 to achieve the purpose of cooling blood vessels, the cooling liquid can be liquid such as normal saline, is harmless to human bodies, can directly enter the blood vessels, can inject sedative and analgesic drug liquid into the drug introducing cavity 6 through the drug administration pipe 15, then enters the blood vessels through the side holes 9 to relieve the pain of patients, and sedative and analgesic drugs such as Midaziram, morphine, remifentanil, fentanil, propofol and the like;

as shown in fig. 4, the cooling liquid cavity 4 includes a circular channel 41 and a plurality of protrusions 42 extending along a radial direction and distributed circumferentially, any drug introducing cavity 6 is located between two adjacent protrusions 42, specifically, the number of the protrusions 42 is three, and two adjacent protrusions 42 are provided with one drug introducing cavity 6, so that the cross-sectional area of the cooling liquid cavity 4 can be maximized, thereby improving the flow rate of the cooling liquid and achieving a better cooling effect;

in order to facilitate the observation of the position of the end part of the catheter 3 during operation, the transistor 8 is provided with two developing points 10, and the two developing points 10 are respectively positioned at two sides of the ultrasonic signal generator 7;

compared with radio frequency RDN ablation, the radio frequency RDN ablation has the advantages that the ultrasonic penetration is stronger, the ablation effect is more excellent, renal artery branch ablation is unnecessary, the ultrasonic ablation catheter is not in direct contact with the blood vessel wall, the damage to the blood vessel wall is minimum, the radio frequency RDN ablation catheter can be used for a blood vessel after stent implantation, the ultrasonic ablation catheter is a cylindrical piezoelectric crystal, high-frequency vibration after electrification can be generated, surrounding tissues can receive ultrasonic waves and heat after the ultrasonic waves, the purpose of ablation is achieved, in addition, the purpose of cooling the blood vessel can be achieved by cooling liquid flowing in the catheter 3, and damage to an inner-layer blood vessel can be avoided to a great extent.

It will be evident to those skilled in the art that the utility model is not limited to the details of the foregoing illustrative embodiments, and that the present utility model may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the utility model being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present disclosure describes embodiments, not every embodiment is provided with a separate embodiment, and that this description is provided for clarity only, and that the disclosure is not limited to the embodiments described in detail below, and that the embodiments described in the examples may be combined as appropriate to form other embodiments that will be apparent to those skilled in the art.

Claims

1. An ultrasonic ablation device comprises an ultrasonic host machine and an operating handle connected with the ultrasonic host machine, and is characterized in that a catheter is arranged on the operating handle, and a cooling liquid cavity, an ablation cavity and a plurality of medicine introducing cavities are arranged in the catheter;

2. The ultrasonic ablation device of claim 1, wherein the operating handle comprises a housing and a cooling fluid reservoir and a drug reservoir disposed within the housing, the cooling fluid reservoir and the cooling fluid chamber being in communication, the drug reservoir and the drug introduction chamber being in communication;

3. An ultrasound ablation device according to claim 1, wherein said coolant cavity comprises a circular channel and a plurality of radially extending, circumferentially distributed lobes, any of said drug introduction cavities being located between adjacent two of the lobes.

4. An ultrasound ablation device according to claim 1, wherein the transistor is provided with two development points, one on each side of the ultrasound signal generator.

5. The ultrasonic ablation device of claim 1, wherein the catheter is sleeved with an insulating sleeve, and through holes are formed in positions of the insulating sleeve corresponding to the side holes.