CN219051189U - Automatic continuous gradient gel preparation device - Google Patents
Automatic continuous gradient gel preparation device Download PDFInfo
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- CN219051189U CN219051189U CN202223546779.6U CN202223546779U CN219051189U CN 219051189 U CN219051189 U CN 219051189U CN 202223546779 U CN202223546779 U CN 202223546779U CN 219051189 U CN219051189 U CN 219051189U
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Abstract
The utility model discloses an automatic continuous gradient gel preparation device which comprises a first solution pushing-out assembly, a second solution pushing-out assembly and a mixing valve, wherein the output end of the first solution pushing-out assembly, the output end of the second solution pushing-out assembly and the input end of the mixing valve are connected through a three-way conduit; the first solution pushing-out component is connected with a first driving component, and the second solution pushing-out component is connected with a second driving component; the device also comprises a control module which is respectively connected with the first driving component and the second driving component. According to the utility model, two solutions to be mixed are respectively filled into the two solution pushing assemblies, the two solutions are pushed into the mixing valve for mixing by using the three-way guide pipe, and the first driving assembly and the second driving assembly are controlled by using the control module, so that the solution pushing speed of one solution pushing assembly is reduced at a constant speed, and the solution pushing speed of the other solution pushing assembly is increased at a constant speed, and finally, the prepared gradient gel can ensure the gradient effect.
Description
Technical Field
The utility model relates to the technical field of biology, in particular to an automatic continuous gradient gel preparation device.
Background
The polyacrylamide gel gradient gel has higher resolution and wide application in biotechnology, but the gradient gel needs continuous gradient concentration in preparation and needs continuous gradient change from the top to the bottom of the gel, and the mode of preparing the gradient gel in the prior art generally adopts gravity to mix two solutions together, so that the operation is complicated and the effect cannot be ensured. In addition, some of the existing methods for preparing gradient gel have the technical problems that the mixing effect is not ideal enough and the mixed solution is not in a complete linear relationship. Other automated production equipment exists in the prior art, but generally these equipment are expensive and are complex to operate and maintain.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides an automatic continuous gradient gel preparation device. The device has low cost, simple structure and convenient operation.
According to one aspect of the application, there is provided an automatic continuous gradient gel preparation device comprising a first solution pushing-out assembly, a second solution pushing-out assembly and a mixing valve, wherein the output end of the first solution pushing-out assembly, the output end of the second solution pushing-out assembly and the input end of the mixing valve are connected through a three-way conduit;
the first solution pushing-out assembly is connected with a first driving assembly for driving the first solution pushing-out assembly to push out the internal solution, and the second solution pushing-out assembly is connected with a second driving assembly for driving the second solution pushing-out assembly to push out the internal solution;
the device also comprises a control module which is respectively connected with the first driving component and the second driving component so as to control the speed of the first driving component driving the first solution pushing component to push out the internal solution and the speed of the second driving component driving the second solution pushing component to push out the internal solution.
According to the automatic continuous gradient gel preparation device, two solutions to be mixed are respectively filled into the two solution pushing assemblies, so that the two solutions can be pushed into the mixing valve for mixing by the three-way guide pipe, the solutions in the two solution pushing assemblies are respectively pushed out by the first driving assembly and the second driving assembly, the amount of the solution pushed out by the solution pushing assemblies can be more accurate, and finally, the first driving assembly and the second driving assembly are controlled by the control module so as to enable the solution pushing speed of one solution pushing assembly to be reduced at a constant speed and the solution pushing speed of the other solution pushing assembly to be increased at a constant speed, and finally, the prepared gradient gel can ensure the gradient effect.
In some embodiments, the first solution pushing assembly is a piston cylinder, and comprises a first cavity and a first push rod for pushing out the solution in the first cavity, and the first driving assembly is connected with the first push rod to drive the first solution pushing assembly to push out the internal solution;
by this, the solution in the first solution pushing-out assembly can be pushed out by the structure of the piston cylinder.
In some embodiments, the first driving assembly comprises a first push plate connected with the first push rod and a first baffle connected with the first cavity, a first screw rod is arranged on the first baffle, a threaded hole in threaded connection with the first screw rod is formed in the first push plate, one end of the first screw rod is rotationally connected to the first baffle, the other end of the first screw rod is connected with a first motor, the first motor is coaxially rotationally connected to a rotating shaft of the first motor, and the control module is connected with the first motor to control the rotating speed of the first motor.
Thus, by this arrangement, the rotational speed of the first screw can be controlled by the first motor, thereby realizing control of the movement speed of the first push plate, so as to realize control of the solution pushing-out speed of the first solution pushing-out assembly.
In some embodiments, the first base is used for installing the first solution pushing-out assembly, and the connecting position of the first base and the first solution pushing-out assembly forms a first baffle.
Therefore, through the arrangement, the first base can be arranged to fix the first solution pushing-out assembly, so that the stable operation of the device is ensured.
In some embodiments, a first slide rail extending along the movement direction of the first push rod is arranged on the first base, a first slide groove matched with the first slide rail is arranged on the first push plate, and the first push plate is arranged on the first base in a sliding manner through the first slide groove and the first slide rail.
Therefore, through the arrangement, the first push plate can slide along the length direction of the first slideway, and the pushing effect of the first push plate is ensured.
In some embodiments, the second solution pushing assembly is a piston cylinder, including a second cavity and a second push rod for pushing out the solution in the second cavity, and the second driving assembly is connected with the second push rod to drive the second solution pushing assembly to push out the internal solution.
By this, the solution in the second solution pushing-out assembly can be pushed out by the structure of the piston cylinder.
In some embodiments, the second driving assembly comprises a second push plate connected with the second push rod and a second baffle connected with the second cavity, a second screw rod is arranged on the second baffle, a threaded hole in threaded connection with the second screw rod is formed in the second push plate, one end of the second screw rod is rotationally connected to the second baffle, the other end of the second screw rod is connected with a second motor, the second motor is coaxially rotationally connected to a rotating shaft of the second motor, and the control module is connected with the second motor to control the rotating speed of the second motor.
Thus, by this arrangement, the rotation speed of the second screw can be controlled by the second motor, thereby realizing control of the movement speed of the second push plate, so as to realize control of the solution pushing-out speed of the second solution pushing-out assembly.
In some embodiments, the second base is used for installing a second solution pushing-out assembly, and a connection position of the second base and the second solution pushing-out assembly forms a second baffle.
Thus, by providing the second base to fix the second solution pushing-out unit, the packaging device can stably operate.
In some embodiments, a second slideway extending along the movement direction of the second push rod is arranged on the second base, a second chute matched with the second slideway is arranged on the second push plate, and the second push plate is arranged on the second base in a sliding way through the second chute and the second slideway.
Therefore, through the arrangement, the second push plate can slide along the length direction of the second slideway, and the pushing effect of the second push plate is packaged.
Drawings
FIG. 1 is a schematic view showing the overall structure of an automatic continuous gradient gel preparation apparatus according to an embodiment of the present utility model;
FIG. 2 is a schematic illustration of an embodiment of an apparatus for preparing an automatic continuous gradient gel according to the present utility model, wherein a mixing valve and a three-way pipe are omitted;
reference numerals illustrate: 1. a first solution pushing assembly; 11. a first cavity; 12. a first push rod; 2. a second solution pushing assembly; 21. a second cavity; 22. a second push rod; 3. a three-way conduit; 4. a mixing valve; 5. a first drive assembly; 51. a first baffle; 52. a first push plate; 53. a first screw; 54. a first motor; 6. a second drive assembly; 61. a second baffle; 62. a second push plate; 63. a second screw; 64. a second motor; 71. a first base; 72. a second base; 81. a first slideway; 82. a first chute; 91. a second slideway; 92. and a second chute.
Detailed Description
The utility model is described in further detail below with reference to the accompanying drawings.
Fig. 1 schematically shows the structure of an automatic continuous gradient gel preparation apparatus according to an embodiment of the present utility model, and referring to fig. 1, the apparatus includes a first solution pushing-out assembly 1, a second solution pushing-out assembly 2, and a mixing valve 4, and the output end of the first solution pushing-out assembly 1 is shown. The output end of the second solution pushing-out assembly 2 and the input end of the mixing valve 4 are connected through a three-way conduit 3. The first solution pushing component 1 is used for pushing out a first solution contained in the first solution pushing component, the second solution pushing component 2 is used for pushing out a second solution contained in the second solution pushing component, so that two different solutions are input into the mixing valve 4 through the three-way conduit 3 for mixing, the mixing valve 4 is a product in the prior art, and the specific internal structure, the use mode and the like can be referred to the related description in the prior art and are not described herein. The first solution pushing-out assembly 1 is further connected with a first driving assembly 5, the second solution pushing-out assembly 2 is further connected with a second driving assembly 6, the first driving assembly 5 is used for driving the first solution pushing-out assembly 1 to push out the solution in the first solution pushing-out assembly, and the second driving assembly 6 is used for driving the second solution pushing-out assembly 2 to push out the solution in the second solution pushing-out assembly. The device further comprises a control module which is respectively connected with the first driving component 5 and the second driving component 6, so that the speed of the first driving component 5 for driving the first solution pushing component 1 to push out the solution in the device and the speed of the second driving component 6 for driving the second solution pushing component 2 to push out the solution in the device are controlled. Specifically, the control module may be a single chip, a CPU, etc., so that the functions of controlling the first driving component 5 and the second driving component 6 can be realized by writing a program, etc., and the specific control manner may refer to the related content in the prior art, which is not an innovation point of the present utility model, but is not described herein too.
Specifically, the first solution pushing-out assembly 1 and the second solution pushing-out assembly 2 may have the same structure due to their similar functions, and may specifically be a piston cylinder structure, such as a syringe. Referring to fig. 2, the first solution pushing assembly 1 includes a first cavity 11 and a first push rod 12 for pushing out the solution in the first cavity 11, so that the solution in the first cavity 11 can be pushed out from the output end of the first solution pushing assembly 1 by pushing the first push rod 12; the second solution pushing-out assembly 2 comprises a second cavity 21 and a second push rod 22 for pushing out the solution in the second cavity 21, and then the solution in the second cavity 21 can be pushed out from the output end of the second solution pushing-out assembly 2 by pushing the second push rod 22. Since in the piston cylinder structure the push rod is driven to realize the function of pushing out the solution inside the cavity, the first drive assembly 5 is connected with the first push rod 12, and the second drive assembly 6 is connected with the second push rod 22.
The first drive unit 5 and the second drive unit 6 may have the same structure since the functions of the first drive unit 5 and the second drive unit 6 are similar. Specifically, referring to fig. 2, the first driving assembly 5 includes a first push plate 52 connected to the first push rod 12 and a first baffle plate 51 connected to the first cavity 11, a first screw rod 53 is rotationally connected to the first baffle plate 51, a threaded hole in threaded connection with the first screw rod 53 is provided on the first push plate 52, the other end of the first screw rod 53 is connected to a first motor 54, and is coaxially rotationally connected to a rotating shaft of the first motor 54, so that when the first motor 54 rotates, the first screw rod 53 is driven to rotate, and the first push plate 52 in threaded connection with the first screw rod 53 moves in a direction approaching or separating from the first baffle plate 51; the second driving assembly 6 comprises a second push plate 62 connected with the second push rod 22 and a second baffle 61 connected with the second cavity 21, a second screw 63 is rotatably connected to the second baffle 61, a threaded hole in threaded connection with the second screw 63 is formed in the second push plate 62, a second motor 64 is connected to the other end of the second screw 63, and the second motor 64 is coaxially rotatably connected to a rotating shaft of the second motor 64, so that when the second motor 64 rotates, the second screw 63 is driven to rotate, and the second push plate 62 in threaded connection with the second screw 63 moves in a direction approaching or separating from the second baffle 61. And for the control module, the rotation speed of the first motor 54 and the rotation speed of the second motor 64 can be controlled by connecting the control module with the first motor 54 and the second motor 64, and finally the speed of the first solution pushing assembly 1 pushing out the solution in the first solution pushing assembly and the speed of the second solution pushing assembly 2 pushing out the solution in the second solution pushing assembly are controlled.
Further, as shown with reference to fig. 2, a first base 71 for mounting the first solution pushing-out assembly 1 and a second base 72 for mounting the second solution pushing-out assembly 2 may be further provided. Specifically, the first motor 54 and the first cavity 11 are both installed on the first base 71, the first baffle 51 is formed at a connection position between the first cavity 11 and the first base 71, the first base 71 may be further provided with a first slide 81 extending along a movement direction of the first push rod 12, and the first push plate 52 is correspondingly provided with a first chute 82 adapted to the first slide 81, so that the first push plate 52 can be slidably disposed on the first base 71 through the first chute 82 and the first slide 81, and a pushing effect of the first push plate 52 is ensured. Correspondingly, the second motor 64 and the second cavity 21 are both installed on the second base 72, the second baffle 61 is formed at the connection position between the second cavity 21 and the second base 72, a second slide rail 91 extending along the movement direction of the second push rod 22 can be further arranged on the second base 72, and a second slide groove 92 matched with the second slide rail 91 is correspondingly arranged on the second push plate 62, so that the second push plate 62 can be slidably arranged on the second base 72 through the second slide groove 92 and the second slide rail 91, and the pushing effect of the second push plate 62 is ensured.
According to the automatic continuous gradient gel preparation device, two solutions to be mixed are respectively filled into the two solution pushing assemblies, so that the two solutions can be pushed into the mixing valve 4 for mixing by the three-way guide pipe 3, the solutions in the two solution pushing assemblies are respectively pushed out by the first driving assembly 5 and the second driving assembly 6, the amount of the solution pushed out by the solution pushing assemblies can be more accurate, and finally the first driving assembly 5 and the second driving assembly 6 are controlled by the control module, so that the solution pushing speed of one solution pushing assembly can be reduced at a constant speed, and the solution pushing speed of the other solution pushing assembly is increased at a constant speed, so that the prepared gradient gel can ensure the gradient effect.
What has been described above is merely some embodiments of the present utility model. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit of the utility model.
Claims (9)
1. Automatic continuous gradient gel preparation facilities, its characterized in that: the device comprises a first solution pushing-out assembly (1), a second solution pushing-out assembly (2) and a mixing valve (4), wherein the output end of the first solution pushing-out assembly (1), the output end of the second solution pushing-out assembly (2) and the input end of the mixing valve (4) are connected through a three-way conduit (3);
the first solution pushing-out assembly (1) is connected with a first driving assembly (5) for driving the first solution pushing-out assembly to push out an internal solution, and the second solution pushing-out assembly (2) is connected with a second driving assembly (6) for driving the second solution pushing-out assembly to push out the internal solution;
the device also comprises a control module which is respectively connected with the first driving component (5) and the second driving component (6) to control the speed of the first driving component (5) for driving the first solution pushing component (1) to push out the solution in the device and the speed of the second driving component (6) for driving the second solution pushing component (2) to push out the solution in the device.
2. The automated continuous gradient gel preparation apparatus of claim 1, wherein: the first solution pushing-out assembly (1) is a piston cylinder body and comprises a first cavity (11) and a first push rod (12) used for pushing out the solution in the first cavity (11), and the first driving assembly (5) is connected with the first push rod (12) so as to drive the first solution pushing-out assembly (1) to push out the internal solution.
3. The automated continuous gradient gel preparation apparatus of claim 2, wherein: the first driving assembly (5) comprises a first push plate (52) connected with the first push rod (12) and a first baffle plate (51) connected with the first cavity (11), a first screw rod (53) is arranged on the first baffle plate (51), a threaded hole in threaded connection with the first screw rod (53) is formed in the first push plate (52), one end of the first screw rod (53) is rotationally connected to the first baffle plate (51), the other end of the first screw rod is connected with a first motor (54) and coaxially rotationally connected to a rotating shaft of the first motor (54), and the control module is connected with the first motor (54) to control the rotating speed of the first motor (54).
4. An automated continuous gradient gel preparation apparatus according to claim 3, wherein: the device further comprises a first base (71) for mounting the first solution pushing-out assembly (1), wherein the connection position of the first base (71) and the first solution pushing-out assembly (1) forms a first baffle plate (51).
5. The automated continuous gradient gel preparation apparatus of claim 4, wherein: the first base (71) is provided with a first slide way (81) extending along the movement direction of the first push rod (12), the first push plate (52) is provided with a first slide way (82) matched with the first slide way (81), and the first push plate (52) is arranged on the first base (71) in a sliding way through the first slide way (82) and the first slide way (81).
6. The automated continuous gradient gel preparation apparatus of claim 1, wherein: the second solution pushing-out assembly (2) is a piston cylinder body and comprises a second cavity (21) and a second push rod (22) for pushing out the solution in the second cavity (21), and the second driving assembly (6) is connected with the second push rod (22) so as to drive the second solution pushing-out assembly (2) to push out the internal solution.
7. The automated continuous gradient gel preparation apparatus of claim 6, wherein: the second driving assembly (6) comprises a second pushing plate (62) connected with the second pushing rod (22) and a second baffle (61) connected with the second cavity (21), a second screw rod (63) is arranged on the second baffle (61), a threaded hole in threaded connection with the second screw rod (63) is formed in the second pushing plate (62), one end of the second screw rod (63) is rotationally connected to the second baffle (61), the other end of the second screw rod is connected with a second motor (64) and coaxially rotationally connected to a rotating shaft of the second motor (64), and the control module is connected with the second motor (64) to control the rotating speed of the second motor (64).
8. The automated continuous gradient gel preparation apparatus of claim 7, wherein: the device further comprises a second base (72) for mounting the second solution pushing-out assembly (2), and a second baffle (61) is formed at the connection position of the second base (72) and the second solution pushing-out assembly (2).
9. The automated continuous gradient gel preparation apparatus of claim 8, wherein: the second base (72) is provided with a second slide way (91) extending along the movement direction of the second push rod (22), the second push plate (62) is provided with a second slide way (92) matched with the second slide way (91), and the second push plate (62) is arranged on the second base (72) in a sliding way through the second slide way (92) and the second slide way (91).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223546779.6U CN219051189U (en) | 2022-12-28 | 2022-12-28 | Automatic continuous gradient gel preparation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223546779.6U CN219051189U (en) | 2022-12-28 | 2022-12-28 | Automatic continuous gradient gel preparation device |
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| Publication Number | Publication Date |
|---|---|
| CN219051189U true CN219051189U (en) | 2023-05-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223546779.6U Active CN219051189U (en) | 2022-12-28 | 2022-12-28 | Automatic continuous gradient gel preparation device |
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| CN (1) | CN219051189U (en) |
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- 2022-12-28 CN CN202223546779.6U patent/CN219051189U/en active Active
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