CN218969201U - Upper cover structure and biological reaction device - Google Patents

Upper cover structure and biological reaction device Download PDF

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Publication number
CN218969201U
CN218969201U CN202223611369.5U CN202223611369U CN218969201U CN 218969201 U CN218969201 U CN 218969201U CN 202223611369 U CN202223611369 U CN 202223611369U CN 218969201 U CN218969201 U CN 218969201U
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Prior art keywords
upper cover
observation window
magnetic attraction
piece
cover shell
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CN202223611369.5U
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Inventor
于搏洋
苏宇静
李飙
邱文文
王力
徐江运
徐龙渤
徐茏林
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Zhejiang JYSS Bio Engineering Co Ltd
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Zhejiang JYSS Bio Engineering Co Ltd
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Abstract

The utility model provides an upper cover structure and a biological reaction device, which relate to the technical field of wave-type bioreactors, and are characterized in that an opening is formed in an upper cover shell, an observation window is rotatably connected to the upper cover shell, so that the observation window can rotate relative to the upper cover shell, the observation window can be switched between an open state and a closed state, the opening can be plugged by the observation window in the closed state, if a cell culture bag in the wave-type bioreactor needs to be operated, the observation window in the open state is tightly attached to the upper cover shell by magnetic attraction generated by a magnetic attraction component, an operator does not need to hold the observation window for a long time, a user can conveniently observe and operate the cell culture bag by opening the observation window when the wave-type bioreactor works, and compared with the traditional upper cover, the opening area of the observation window is smaller, and the influence on the heat preservation effect is smaller.

Description

Upper cover structure and biological reaction device
Technical Field
The utility model relates to the technical field of wave-type bioreactors, in particular to an upper cover structure and a bioreactor.
Background
The wave bioreactor is to place cells and culture fluid in a sterile cell culture bag on a specially designed shaker structure. Waves are generated in the culture solution by shaking the shaking table structure, and the waves enable gas to be in contact with the surface of the culture to realize oxygen transmission, so that a culture environment with low shearing force and relatively high oxygen transmission efficiency is generated, and efficient culture growth of cells and production of target products are realized.
The wave-type bioreactor comprises a shaking table structure and a swinging power assembly arranged at the lower part of the shaking table, wherein cells and culture solution are arranged in a sterile closed cell culture bag and are arranged on the shaking table structure. The swinging power component provides swinging motion for the swinging bed, so that waves are generated in the culture solution. The shaker structure often includes the upper cover that is used for guaranteeing cell culture bag heat preservation effect and with the shaker tray of upper cover mutually supporting. In the cell culture process, the upper cover and the shaking table tray wrap the cell culture bag, thereby playing a role in heat preservation.
However, in the cell culture process, the upper cover is required to be completely opened to observe, sample and other operations on the cell culture bag, so that the heat preservation effect is not only affected, but also the operation difficulty is increased.
Disclosure of Invention
The utility model aims to provide an upper cover structure and a biological reaction device, so as to solve the technical problems that in the prior art, a wave biological reactor can operate a cell culture bag only by completely opening an upper cover in the cell culture process, the heat preservation effect is affected and the operation difficulty is increased.
The utility model provides an upper cover structure, which is used in a wave-type bioreactor and comprises the following components: the device comprises an upper cover shell, an observation window and a magnetic attraction component;
the upper cover shell is provided with an opening;
the observation window is rotationally connected with the upper cover shell, and when the observation window is in a closed state, the opening is plugged by the observation window;
the magnetic attraction component is respectively connected with the upper cover shell and the observation window, and the magnetic attraction force generated by the magnetic attraction component is used for fixing the observation window in an opened state on the upper cover shell.
Further, the method comprises the steps of,
the upper cover shell is positioned at the opening and is extended with an upper cover outer edge, and the upper cover outer edge abuts against the observation window in a closed state.
Further, the method comprises the steps of,
the upper cover structure further comprises a rotary connecting piece;
the rotation connecting piece is provided with first connecting portion and the second connecting portion of mutual articulated, first connecting portion with the inside wall of observation window is connected, the second connecting portion with the inside wall of upper cover casing is connected.
Further, the method comprises the steps of,
the magnetic attraction component comprises a first magnetic attraction piece and a second magnetic attraction piece;
the first magnetic attraction piece is arranged on the outer side wall of the observation window, the second magnetic attraction piece is arranged on the outer side wall of the upper cover shell, and the magnetic pole of the first magnetic attraction piece is different from the magnetic pole of the second magnetic attraction piece.
Further, the method comprises the steps of,
the magnetic component also comprises a first backing plate;
the lateral wall of observation window is provided with first recess, first magnetism inhale the piece set up in the first recess, first backing plate with the observation window is connected, just the bottom surface lid of first backing plate is established the notch of first recess.
Further, the method comprises the steps of,
the magnetic attraction member further comprises a first fastener;
one end of the first fastener is connected with the first backing plate, and the other end of the first fastener penetrates through the observation window to be connected with the first connecting portion.
Further, the method comprises the steps of,
the magnetic component also comprises a second backing plate;
the lateral wall of upper cover casing is provided with the second recess, the second magnetism inhale the piece set up in the second recess, the second backing plate with the upper cover casing is connected, just the bottom surface lid of second backing plate is established the notch of second recess.
Further, the method comprises the steps of,
the magnetic attraction member further comprises a second fastener;
one end of the second fastening piece is connected with the second base plate, and the other end of the second fastening piece penetrates through the upper cover shell to be connected with the second connecting portion.
Further, the method comprises the steps of,
the outer side wall of the observation window is provided with a handle.
The biological reaction device provided by the utility model comprises the upper cover structure.
According to the upper cover structure provided by the utility model, the opening is formed in the upper cover shell, the observation window is rotationally connected to the upper cover shell, so that the observation window can rotate relative to the upper cover shell and can be switched between the open state and the closed state, the opening can be blocked by the observation window in the closed state, if the operation of the cell culture bag in the wave bioreactor is required, the observation window is opened, the observation window in the open state is tightly attached to the upper cover shell by the magnetic attraction generated by the magnetic attraction component, an operator does not need to hold the observation window for a long time, a user can conveniently observe and operate the cell culture bag when the wave bioreactor works, compared with the traditional upper cover, the opening area of the observation window is smaller, the influence on the heat preservation effect is smaller, the operation of the cell culture bag can be realized only by completely opening the upper cover in the cell culture process of the wave bioreactor in the prior art, the heat preservation effect is influenced, and the technical problem of operation difficulty is increased.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present utility model, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic diagram of the overall structure of an upper cover structure according to an embodiment of the present utility model;
fig. 2 is a schematic structural diagram of an observation window and a magnetic component in an upper cover structure according to an embodiment of the present utility model;
fig. 3 is a schematic structural view of an upper cover shell in an upper cover structure according to an embodiment of the present utility model.
Icon: 100-an upper cover housing; 110-a second groove; 200-observation window; 210-a first groove; 220-handle; 300-magnetic attraction component; 310-a first magnetic attraction piece; 320-a first pad; 330-a second pad; 340-a first fastener; 400-rotating connection.
Detailed Description
The technical solutions of the present utility model will be clearly and completely described in connection with the embodiments, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
The shaking table structure in the wave bioreactor often includes the upper cover that is arranged in guaranteeing cell culture bag heat preservation effect and the shaking table tray that mutually supports with the upper cover, at cell culture in-process, upper cover and shaking table tray parcel cell culture bag, although played the heat preservation effect, at cell culture in-process, need open the upper cover completely just can observe, operation such as sample, have not only influenced heat preservation effect, have still increased the degree of difficulty of operation.
In view of this, as shown in fig. 1, 2 and 3, the upper cover structure provided in this embodiment is used in a wave bioreactor, and includes: an upper cover case 100, an observation window 200, and a magnetic attraction member 300; the upper cover case 100 is provided with an opening; the observation window 200 is rotatably connected with the upper cover shell 100, and when the observation window 200 is in a closed state, the observation window 200 seals the opening; the magnetic attraction members 300 are respectively connected to the upper cover case 100 and the observation window 200, and the magnetic attraction force generated by the magnetic attraction members 300 is used to fix the observation window 200 in the opened state to the upper cover case 100.
Specifically, the upper cover shell 100 is used as an upper cover of the wave reactor, the upper cover shell 100 is provided with an opening, the observation window 200 is arranged at the opening, the observation window 200 is rotationally connected to the upper cover shell 100, the observation window 200 can rotate relative to the upper cover shell 100, the observation window 200 can be opened, when the observation window 200 is in an opened state, the observation window 200 is turned upwards, the opening is opened, a cell culture bag wrapped by the upper cover shell 100 can be operated, compared with the traditional integral upper cover shell 100, the opening area of the observation window 200 is smaller, heat loss is smaller, the heat preservation effect is effectively improved, when the observation window 200 is in a closed state, the observation window 200 rotates to a position for blocking the opening, and the opening on the upper cover shell 100 is blocked by the observation window 200, so that the cell culture bag is completely wrapped.
In order to facilitate the fixing of the observation window 200 in the open state, a magnetic attraction member 300 is provided, the magnetic attraction member 300 is located between the observation window 200 and the upper cover housing 100, when the observation window 200 is in the open state, the magnetic force generated by the magnetic attraction member 300 acts on the observation window 200 and the upper cover housing 100, so that the observation window 200 can be fixed on the upper cover housing 100, an operator does not need to support the observation window 200 by using both hands, the operator can be liberated from both hands, and other operations can be conveniently performed by the operator.
According to the upper cover structure provided by the embodiment, the upper cover shell 100 is provided with the opening, the observation window 200 is rotationally connected with the upper cover shell 100, so that the observation window 200 can rotate relative to the upper cover shell 100, the opening state and the closing state are switched, the observation window 200 in the closing state can be used for blocking the opening, if the cell culture bag in the wave bioreactor needs to be operated, the observation window 200 is opened, the observation window 200 in the opening state is tightly attached to the upper cover shell 100 due to the magnetic attraction generated by the magnetic attraction component 300, an operator does not need to hold the observation window 200 for a long time, the observation window 200 is conveniently opened for observing and operating the cell culture bag when the wave bioreactor works, and compared with the traditional upper cover, the opening area of the observation window 200 is smaller, the influence on the heat preservation effect is smaller, the technical problem that in the prior art, the wave bioreactor needs to completely open the upper cover to operate the cell culture bag in the cell culture process, the heat preservation effect is relieved, and the operation difficulty is increased.
Further, in the upper cover structure provided in this embodiment, the upper cover outer edge of the upper cover shell 100 extends at the opening, and the upper cover outer edge abuts against the observation window 200 in the closed state.
Specifically, the opening of the upper cover casing 100 extends outward to form an upper cover outer edge, when the observation window 200 is in a closed state, the outer edge of the observation window 200 abuts against the upper cover outer edge, and compared with the case that the observation window 200 directly seals the opening, the arrangement of the upper cover outer edge effectively reduces the gap between the observation window 200 and the upper cover casing 100, and the heat preservation effect is better.
In addition, as an alternative embodiment, the outer edge of the observation window 200 may be provided with a recess inwardly, the recess is matched with the shape of the outer edge of the upper cover, and when the observation window 200 is in the closed state, the outer edge of the upper cover extends into the recess, so that the outer surface of the observation window 200 is flush with the outer surface of the upper cover housing 100, and the attractive appearance is increased while the gap between the observation window 200 and the opening of the upper cover housing 100 is reduced.
Further, the upper cover structure further includes a rotation connector 400; the rotary connector 400 is provided with a first connecting portion and a second connecting portion hinged to each other, the first connecting portion being connected with the inner sidewall of the observation window 200, and the second connecting portion being connected with the inner sidewall of the upper cover case 100.
Specifically, the first connection portion and the second connection portion are respectively connected to the viewing window 200 and the upper cover case 100, and the first connection portion and the second connection portion are hinged to each other, so that the rotational connection between the viewing window 200 and the upper cover case 100 can be achieved.
The rotation connector 400 may be specifically configured as a hinge structure, and is composed of a leaf and a leaf shaft, where the first connection portion and the second connection portion are respectively a first leaf and a second leaf, the first leaf and the second leaf are connected by the leaf shaft, the first leaf is fixed on an inner side wall of the observation window 200 by a bolt, the second leaf is fixed on an inner side wall of the upper cover housing 100 by a bolt, and the observation window 200 can rotate relative to the upper cover housing 100 by hinging the first leaf and the second leaf.
In addition, the rotation connector 400 may be provided as a hinge structure, and rotation of the viewing window 200 with respect to the upper cover case 100 is achieved by using a hinge.
Further, the magnetic attraction member 300 includes a first magnetic attraction 310 and a second magnetic attraction; the first magnetic attraction piece 310 is disposed on the outer sidewall of the observation window 200, the second magnetic attraction piece is disposed on the outer sidewall of the upper cover housing 100, and the magnetic pole of the first magnetic attraction piece 310 is different from the magnetic pole of the second magnetic attraction piece.
Specifically, the first magnetic attraction piece 310 and the second magnetic attraction piece can be set to be magnets, the magnetic poles of the first magnetic attraction piece 310 and the second magnetic attraction piece are different, when the observation window 200 rotates from a closed state to an open state, the first magnetic attraction piece 310 on the observation window 200 is close to the second magnetic attraction piece on the upper cover shell 100, the first magnetic attraction piece 310 and the second magnetic attraction piece are mutually attached due to magnetic force, and then the observation window 200 is tightly attached to the upper cover shell 100, and the observation window 200 can be always in the open state without being held by hands.
In addition, as an alternative embodiment, the first magnetic attraction member 310 may be provided as a magnet, the second magnetic attraction member may be provided as a metal member, the magnet may generate a magnetic force on the metal member, or the first magnetic attraction member 310 may be provided as a metal member, the second magnetic attraction member may be provided as a magnet, and the first magnetic attraction member 310 and the second magnetic attraction member of different materials may be selected according to actual needs.
Further, the magnetic attraction member 300 further includes a first backing plate 320; the outer side wall of the observation window 200 is provided with a first groove 210, the first magnetic attraction piece 310 is arranged in the first groove 210, the first base plate 320 is connected with the observation window 200, and the bottom surface of the first base plate 320 covers the notch of the first groove 210.
Specifically, in order to embed the first magnetic attraction piece 310 in the observation window 200, a first groove 210 is formed in the observation window 200, the first magnetic attraction piece 310 is placed in the first groove 210, and a first backing plate 320 is installed at a notch of the first groove 210, and the size of the first backing plate 320 is larger than that of the first groove 210, so that the first backing plate 320 can block the notch of the first groove 210, and the first magnetic attraction piece 310 can be fixed in the first groove 210.
Further, the magnetic attraction member 300 further includes a first fastener 340; one end of the first fastener 340 is coupled to the first backing plate 320, and the other end of the first fastener 340 is coupled to the first coupling portion through the viewing window 200.
Specifically, the first fastening member 340 fixes the first backing plate 320 on the observation window 200, the first fastening member 340 has a columnar structure, one end of the first fastening member 340 is fixed on the first backing plate 320, a through hole is formed in a position of the observation window 200 corresponding to the first fastening member 340, the first fastening member 340 penetrates through the through hole on the observation window 200 and penetrates out of the first connecting portion, and the end portion of the first fastening member 340 can be fixed by using a nut, so that the first backing plate 320 can be fixed on the observation window 200 by the first fastening member 340.
Further, the magnetic attraction member 300 further includes a second pad 330; the outer side wall of the upper cover shell 100 is provided with a second groove 110, the second magnetic attraction piece is arranged in the second groove 110, the second base plate 330 is connected with the upper cover shell 100, and the bottom surface of the second base plate 330 covers the notch of the second groove 110.
Specifically, the second backing plate 330 has the same principle as the first backing plate 320, and the second magnetic attraction piece can be limited in the second groove 110 by blocking the notch of the second groove 110 with the second backing plate 330.
Further, the magnetic attraction member 300 further includes a second fastener; one end of the second fastener is connected to the second pad 330, and the other end of the second fastener passes through the upper cover case 100 to be connected to the second connection part.
Specifically, the first fastening member 340 and the second fastening member are coupled in the same manner, and the second pad 330 is fixed to the upper cover case 100 by the second fastening member.
It should be noted that, the outer edges of the first pad 320 and the second pad 330 are both arc structures, so that sharp protruding parts are avoided, and scratch is effectively prevented when the cell culture bag is put in or taken out.
To facilitate opening the viewing window 200, further, the outer sidewall of the viewing window 200 is provided with a handle 220.
In addition, upper cover casing 100 and observation window 200 adopt light-duty plastics preparation, reduce the overall quality of upper cover structure, make things convenient for the user to operate, all be equipped with unsmooth design on upper cover casing 100 and the observation window 200, unsmooth structural design improves the structural strength of working of plastics.
It should be noted that, a plurality of observation windows 200 may also be provided on the upper cover housing 100, so as to satisfy the user's requirements and facilitate the operation of a plurality of cell culture bags.
The upper cover structure provided in this embodiment adopts a magnetic attraction mode to turn up the observation window 200, and the observation window 200 and the upper cover are magnetically attracted and fixed, so that the observation window 200 is prevented from being damaged due to sliding down.
The biological reaction device provided in this embodiment includes an upper cover structure.
Since the technical effects of the bioreactor provided in this embodiment are the same as those of the upper cover structure provided in the above embodiment, the description thereof will not be repeated here.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and not for limiting the same; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the utility model.

Claims (10)

1. An upper cover structure for use in a wave bioreactor, comprising: an upper cover housing (100), an observation window (200), and a magnetic attraction member (300);
the upper cover shell (100) is provided with an opening;
the observation window (200) is rotationally connected with the upper cover shell (100), and when the observation window (200) is in a closed state, the opening is blocked by the observation window (200);
the magnetic attraction component (300) is respectively connected with the upper cover shell (100) and the observation window (200), and the magnetic attraction force generated by the magnetic attraction component (300) is used for fixing the observation window (200) in an open state on the upper cover shell (100).
2. The upper cover structure according to claim 1, wherein,
the upper cover shell (100) is positioned at the opening and is extended with an upper cover outer edge, and the upper cover outer edge is propped against the observation window (200) in a closed state.
3. The upper cover structure according to claim 2, wherein,
the upper cover structure further comprises a rotary connecting piece (400);
the rotary connecting piece (400) is provided with a first connecting part and a second connecting part which are mutually hinged, the first connecting part is connected with the inner side wall of the observation window (200), and the second connecting part is connected with the inner side wall of the upper cover shell (100).
4. The upper cover structure according to claim 3, wherein,
the magnetic attraction member (300) comprises a first magnetic attraction piece (310) and a second magnetic attraction piece;
the first magnetic attraction piece (310) is arranged on the outer side wall of the observation window (200), the second magnetic attraction piece is arranged on the outer side wall of the upper cover shell (100), and the magnetic pole of the first magnetic attraction piece (310) is different from the magnetic pole of the second magnetic attraction piece.
5. The upper cover structure according to claim 4, wherein,
the magnetic attraction member (300) further comprises a first backing plate (320);
the lateral wall of observation window (200) is provided with first recess (210), first magnetism inhale piece (310) set up in first recess (210), first backing plate (320) with observation window (200) are connected, just the bottom surface lid of first backing plate (320) is established the notch of first recess (210).
6. The upper cover structure according to claim 5, wherein,
the magnetically attractable member (300) further includes a first fastener (340);
one end of the first fastening piece (340) is connected with the first backing plate (320), and the other end of the first fastening piece (340) penetrates through the observation window (200) to be connected with the first connecting portion.
7. The upper cover structure according to claim 4, wherein,
the magnetic attraction member (300) further comprises a second backing plate (330);
the outer side wall of the upper cover shell (100) is provided with a second groove (110), the second magnetic attraction piece is arranged in the second groove (110), the second base plate (330) is connected with the upper cover shell (100), and the bottom surface of the second base plate (330) is covered with a notch of the second groove (110).
8. The cover structure according to claim 7, wherein,
the magnetically attractable member (300) further includes a second fastener;
one end of the second fastening piece is connected with the second backing plate (330), and the other end of the second fastening piece penetrates through the upper cover shell (100) to be connected with the second connecting portion.
9. The structure as claimed in any one of claims 1 to 8, wherein,
the outer side wall of the observation window (200) is provided with a handle (220).
10. A bioreactor apparatus comprising a cover structure as claimed in any one of claims 1 to 9.
CN202223611369.5U 2022-12-30 2022-12-30 Upper cover structure and biological reaction device Active CN218969201U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223611369.5U CN218969201U (en) 2022-12-30 2022-12-30 Upper cover structure and biological reaction device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223611369.5U CN218969201U (en) 2022-12-30 2022-12-30 Upper cover structure and biological reaction device

Publications (1)

Publication Number Publication Date
CN218969201U true CN218969201U (en) 2023-05-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223611369.5U Active CN218969201U (en) 2022-12-30 2022-12-30 Upper cover structure and biological reaction device

Country Status (1)

Country Link
CN (1) CN218969201U (en)

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