CN218962442U

CN218962442U - Reaction equipment for preparing vorofan fumarate

Info

Publication number: CN218962442U
Application number: CN202222974549.3U
Authority: CN
Inventors: 李华伟; 闫玉建; 张倩倩
Original assignee: Jinan Asia Pharma Tech Co ltd
Current assignee: Jinan Asia Pharma Tech Co ltd
Priority date: 2022-11-09
Filing date: 2022-11-09
Publication date: 2023-05-05
Anticipated expiration: 2032-11-09

Abstract

The utility model belongs to the technical field of drug reaction, and particularly discloses reaction equipment for preparing voronoi fumarate, which comprises a workbench, wherein a driving mechanism is arranged on the lower surface of the workbench, a mixing barrel is fixedly connected to the upper surface of the workbench, a grinding head is connected in the mixing barrel through the driving mechanism, a grinding ring is fixedly connected to the outer side of the grinding head through a fixing frame, a grinding column is arranged above the grinding head, and the grinding column is in vertical sliding fit with the grinding ring.

Description

Reaction equipment for preparing vorofan fumarate

Technical Field

The utility model belongs to the technical field of drug reaction, and particularly discloses reaction equipment for preparing vonoprazan fumarate.

Background

Vonoprazan fumarate is a novel proton pump inhibitor and is mainly used for treating acid-related gastrointestinal diseases, raw materials are required to be stirred and crushed in the Vonoprazan fumarate preparation process and then mixed with other auxiliary materials for reaction, the mixing efficiency of the existing reaction equipment is low, and the existing reaction equipment for preparing Vonoprazan fumarate is provided.

Disclosure of Invention

The utility model aims to solve the defect of slow mixing process of the existing Vonoprazan fumarate production equipment, and provides a reaction equipment for preparing Vonoprazan fumarate.

In order to achieve the above purpose, the utility model provides a reaction device for producing voronoi fumarate, which comprises a workbench, wherein a driving mechanism is arranged on the lower surface of the workbench, a mixing barrel is fixedly connected to the upper surface of the workbench, a grinding head is connected to the mixing barrel through the driving mechanism, a grinding ring is fixedly connected to the outer side of the grinding head through a fixing frame, a grinding column is arranged above the grinding head, the grinding column is in vertical sliding fit with the grinding ring, and a lifting mechanism is arranged on the outer side of the mixing barrel.

Preferably, the driving mechanism comprises a fixed cover fixedly arranged on the lower surface of the workbench, a motor is fixedly arranged in the fixed cover, an output shaft of the motor is fixedly connected with a transmission shaft, the transmission shaft penetrates through the workbench and extends into the mixing barrel, and the end part of the transmission shaft is fixedly connected with the lower surface of the grinding head.

Preferably, the upper surface of the grinding column is fixedly connected with a sealing cover, and the sealing cover is movably sleeved on the outer side of the mixing barrel.

Preferably, the lifting mechanism comprises a first telescopic rod fixedly connected to one side surface of the sealing cover, a second telescopic rod fixedly connected to the other side surface of the sealing cover, a rubber pad is fixedly connected to the inside of the sealing cover, a thermometer is fixedly connected to the upper surface of the sealing cover, and the thermometer penetrates through the upper surface of the sealing cover and extends into the mixing barrel.

Preferably, the inner surface of the mixing barrel is fixedly connected with a heating plate, and the outer surface of the heating plate is provided with a slope surface.

Preferably, the outside of the transmission shaft is fixedly sleeved with stirring blades below the grinding ring, and the outside of the mixing barrel is fixedly provided with a drain valve close to the workbench.

Compared with the prior art, the utility model has the following beneficial effects: the equipment grinds the raw materials clamped in the middle of the grinding column through the grinding head, and the grinded raw materials can be quickly mixed with other auxiliary materials fused into liquid for reaction. The whole device is simple and practical, reduces the reaction time and improves the production efficiency.

Drawings

Fig. 1 is a schematic structural diagram of a reaction apparatus for preparing vorofacian fumarate according to the present utility model;

fig. 2 is a schematic diagram of the other side structure of a reaction apparatus for preparing vorofacian fumarate according to the present utility model;

fig. 3 is a sectional view of a mixing barrel of a reaction apparatus for preparing vorofan fumarate according to the present utility model;

fig. 4 is an enlarged view of a voronoi fumarate reaction apparatus of fig. 3 according to the present utility model.

In the figure: 1. a work table; 2. a motor; 3. a mixing barrel; 4. a fixed cover; 5. a transmission shaft; 6. a grinding head; 7. sealing cover; 8. grinding the column; 9. a grinding ring; 10. a fixing frame; 11. a drain valve; 12. stirring the leaves; 13. a slope surface; 14. a rubber pad; 15. a first telescopic rod; 16. a second telescopic rod; 17. a heating plate; 18. a thermometer.

Detailed Description

In order that the above-recited objects, features and advantages of the present utility model will be more clearly understood, a more particular description of the utility model will be rendered by reference to the appended drawings and appended detailed description.

The reaction equipment for preparing voronoi fumarates shown in fig. 1-4 comprises a workbench 1, wherein a driving mechanism is arranged on the lower surface of the workbench 1, a mixing barrel 3 is fixedly connected to the upper surface of the workbench 1, a grinding head 6 is connected to the mixing barrel 3 through the driving mechanism, a grinding ring 9 is fixedly connected to the outer side of the grinding head 6 through a fixing frame 10, a grinding column 8 is arranged above the grinding head 6, the grinding column 8 and the grinding ring 9 are in vertical sliding fit, a lifting mechanism is arranged on the outer side of the mixing barrel 3, and the use experience is increased by avoiding manpower work.

The actuating mechanism includes fixed cover 4 of fixed mounting at workstation 1 lower surface, fixed cover 4 internal fixation has motor 2, plays fixed action to motor 2, prevents to appear unstable phenomenon in the operation in-process, and motor 2 output shaft fixedly connected with transmission shaft 5, area are used for driving grinding head 6, and transmission shaft 5 runs through workstation 1 and extends to in the compounding bucket 3, and the lower surface of transmission shaft 5 tip fixed connection grinding head 6 plays the grinding action to Vonoprazan fumarate, reduces reaction time.

The upper surface of the grinding column 8 is fixedly connected with a sealing cover 7, the sealing cover 7 is movably sleeved outside the mixing barrel 3, steam generated by heating is sealed in the mixing barrel 3, and the influence of steam loss on the product quality is avoided.

Elevating system includes fixed connection at the first telescopic link 15 of sealed lid 7 one side surface, sealed lid 7 opposite side surface fixedly connected with second telescopic link 16, stability when sealed lid 7 reciprocates is increased to first telescopic link 15 and second telescopic link 16, fixed connection has rubber pad 14 in the sealed lid 7, increase the frictional force of sealed lid 7 and mixing drum 3, prevent steam loss, sealed lid 7 upper surface fixedly connected with thermometer 18, and thermometer 18 runs through sealed lid 7 upper surface and extends to in the mixing drum 3, more audio-visual temperature in the mixing drum 3 of observing, more audio-visual reaction progress of observing.

The inner surface of the mixing barrel 3 is fixedly connected with a heating plate 17, an electric heating plate is selected, the temperature control is convenient and quick, the outer surface of the heating plate 17 is provided with a slope surface 13 for assisting the discharge valve 11 in discharging, and materials are prevented from remaining in the barrel, so that resources are saved.

The transmission shaft 5 outside is located the fixed cover of grinding ring 9 below and is equipped with stirring leaf 12, and the compounding bucket 3 outside is close to workstation 1 fixed mounting and has drain valve 11, and stirring leaf 12 can let the more even melting of auxiliary material in the compounding bucket 3 promote heating efficiency, and the material after the reaction is accomplished discharges along with drain valve 11.

In the work, the first telescopic rod 15 and the second telescopic rod 16 are firstly operated to lift the sealing cover 7 to a proper height, the needed reaction auxiliary materials are placed in the mixing barrel 3, then the raw materials are placed in the grinding ring 9, and then the sealing cover 7 is lowered to a proper position, and then the heating plate 17 and the motor 2 are started to react. The grinding head 6 driven by the motor 2 grinds the raw materials clamped in the middle of the grinding column 8, the stirring blade 12 below the grinding head 6 is matched with the heating plate 17 to melt the auxiliary materials, the thermometer 18 above the sealing cover 7 is observed, the sealing cover 7 is lifted to a proper height after the auxiliary materials in the mixing barrel 3 are melted into liquid, the raw materials ground in the grinding ring 9 are mixed in the mixing barrel 3 for reaction, and the raw materials are discharged from the drain valve 11 after the reaction is completed.

The foregoing has shown and described the basic principles, principal features and advantages of the utility model. It will be understood by those skilled in the art that the present utility model is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present utility model, and various changes and modifications may be made therein without departing from the spirit and scope of the utility model, which is defined by the appended claims. The scope of the utility model is defined by the appended claims and equivalents thereof.

Claims

1. The utility model provides a reaction equipment of preparation fumaric acid Vonoprazan, includes workstation (1), workstation (1) lower surface is provided with actuating mechanism, fixed surface is connected with compounding bucket (3), its characterized in that on workstation (1): the grinding device is characterized in that a grinding head (6) is connected in the mixing barrel (3) through a driving mechanism, a grinding ring (9) is fixedly connected to the outer side of the grinding head (6) through a fixing frame (10), a grinding column (8) is arranged above the grinding head (6), the grinding column (8) and the grinding ring (9) are in vertical sliding fit, and a lifting mechanism for driving the grinding column (8) to move up and down is arranged on the outer side of the mixing barrel (3).

2. The reaction apparatus for preparing vorexant fumarate according to claim 1, wherein: the driving mechanism comprises a fixed cover (4) fixedly arranged on the lower surface of the workbench (1), a motor (2) is fixedly arranged in the fixed cover (4), an output shaft of the motor (2) is fixedly connected with a transmission shaft (5), the transmission shaft (5) penetrates through the workbench (1) and extends into the mixing barrel (3), and the end part of the transmission shaft (5) is fixedly connected with the lower surface of the grinding head (6).

3. The reaction apparatus for preparing vorexant fumarate according to claim 1, wherein: the upper surface of the grinding column (8) is fixedly connected with a sealing cover (7), and the sealing cover (7) is movably sleeved on the outer side of the mixing barrel (3).

4. A reaction apparatus for preparing vorexant fumarate according to claim 3, wherein: elevating system includes first telescopic link (15) of fixed connection at sealed lid (7) one side surface, sealed lid (7) opposite side surface fixedly connected with second telescopic link (16), fixedly connected with rubber pad (14) in sealed lid (7), sealed lid (7) upper surface fixedly connected with thermometer (18), just thermometer (18) run through sealed lid (7) upper surface and extend to in compounding bucket (3).

5. The reaction apparatus for preparing vorexant fumarate according to claim 1, wherein: the inner surface of the mixing barrel (3) is fixedly connected with a heating plate (17), and the outer surface of the heating plate (17) is provided with a slope surface (13).

6. A reaction apparatus for preparing vorexant fumarate according to claim 2, wherein: the stirring blade (12) is fixedly sleeved below the grinding ring (9) on the outer side of the transmission shaft (5), and the drain valve (11) is fixedly installed on the outer side of the mixing barrel (3) close to the workbench (1).