CN218943601U

CN218943601U - Self-expanding metal coated stent of slow-release hormone medicine for preventing esophageal stenosis

Info

Publication number: CN218943601U
Application number: CN202221426938.6U
Authority: CN
Inventors: 王立民; 安薇; 施新岗; 郭章允
Original assignee: Individual
Current assignee: Individual
Priority date: 2022-06-09
Filing date: 2022-06-09
Publication date: 2023-05-02
Anticipated expiration: 2032-06-09

Abstract

The utility model provides a slow-release hormone drug self-expanding metal covered stent for preventing esophageal stenosis. The slow release type hormone drug self-expanding metal coated stent for preventing esophageal stenosis comprises a main body stent, wherein two ends of the main body stent are tubular open ends with slightly larger calibers. The self-expanding metal coated stent for preventing the esophageal stenosis controls the quantity and distribution of the stored slow-release glucocorticoid through the quantity and distribution of the small capsule medicament bins uniformly distributed on the outer side surface of the silica gel coated film, so that the medicament distribution is more uniform, the local accumulation of the medicament is avoided, the slow-release glucocorticoid uniformly permeates and disperses to all lesion surfaces according to a certain constant speed in a longer time through the uniformly distributed sieve-shaped side holes, the anti-inflammatory and anti-fibrosis formation degree of the esophageal wound surface is effectively controlled, and the condition that the injury to a certain extent is caused to a patient due to the stenosis caused by the anti-inflammatory and fibrosis formation in the esophageal repair process is prevented.

Description

Self-expanding metal coated stent of slow-release hormone medicine for preventing esophageal stenosis

Technical Field

The utility model relates to the technical field of metal stents, in particular to a slow-release hormone drug self-expanding metal coated stent for preventing esophageal stenosis.

Background

Esophageal cancer, also called esophageal cancer, is a malignant tumor occurring in the epithelial tissue of esophagus, and is classified into early, middle and late stages, and the common treatment methods include surgical treatment, chemotherapy treatment and drug treatment. Smoking and drinking are causes of esophagus cancer, and the esophagus cancer is one of high-grade tumor in China, and the morbidity and mortality of the high-grade tumor are gradually increased.

The method for carrying the medicine mainly binds small tubes and small balls on the stent, which is easy to cause local concentration and uneven distribution of the medicine and leads to the failure of the local medicine.

Therefore, it is necessary to provide a new slow-release hormone drug self-expanding metal coated stent for preventing esophageal stenosis to solve the above technical problems.

Disclosure of Invention

In order to solve the technical problems, the utility model provides a slow-release hormone drug self-expanding metal coated stent for preventing esophageal stenosis.

The utility model provides a slow release hormone drug self-expanding metal covered stent for preventing esophageal stenosis, which comprises the following components: including the main part support, the both ends of main part support set up to the slightly big tubular open end of bore, and the one end of main part support is provided with first portion of traveling, and is provided with the inflow way on the terminal surface of main part support one end, the one end that is close to the inflow way of tubular open end is equipped with the recovery line, the other end of main part support is provided with the second portion of traveling, and be provided with the outflow way on the terminal surface of main part support other end, all cover the silica gel tectorial membrane on main part support, tubular open end, first portion of traveling and the second portion of traveling, the lateral surface of silica gel tectorial membrane is provided with evenly distributed's little saccular medicine storehouse, a plurality of evenly distributed's sieve form side openings have been seted up to the surface in little saccular medicine storehouse, slowly-releasing glucocorticoid is equipped with in little saccular medicine storehouse.

Preferably, the main body support is dumbbell-shaped.

Preferably, the main body support is made of titanium-nickel shape memory alloy.

Preferably, the main body support is in a grid structure.

Compared with the related art, the slow-release hormone drug self-expanding metal coated stent for preventing esophageal stenosis has the following beneficial effects:

1. the utility model provides a self-expanding metal coated stent of a slow-release type hormone medicine for preventing esophageal stenosis, which controls the quantity and distribution of slow-release type glucocorticoid stored by the quantity and distribution of small capsule medicine cabins uniformly distributed on the outer side surface of a silica gel coated film, so that the medicine distribution is more uniform, the local accumulation of the medicine is avoided, the slow-release type glucocorticoid uniformly permeates and disperses to the surface of all lesions according to a certain constant speed in a longer time by uniformly distributed sieve-shaped side holes, the anti-inflammatory and anti-fibrosis formation degree of an esophageal wound surface is effectively controlled, the condition that the stenosis caused by the anti-inflammatory and anti-fibrosis formation in the esophageal wound surface is prevented from causing a certain degree of injury to a patient is prevented, the slow-release type hormone medicine reaches the injured part of the esophagus by the local administration of the permeation and dispersion principle, the systemic steroid medicine is not needed, the serious complications such as infection, diabetes, osteoporosis and the like caused by the existence of the systemic steroid medicine are well solved, the problems of inconsistent local injection reproducibility and the short duration are effectively solved, and the risk of delayed perforation or wall abscess caused by local injection is avoided.

2. The utility model provides a slow-release hormone drug self-expanding metal covered stent for preventing esophageal stenosis, which is made of a titanium-nickel shape memory alloy material with special materials, has a memory function, is self-expanded and expanded after being released to an esophageal injury part, plays a role in continuous mechanical expansion and shaping better than the conventional self-expanding endoscopic metal stent in the esophageal wound repair process, simultaneously stores slow-release glucocorticoid through small capsule drug bins uniformly distributed on the outer side surface of a covered film, plays an anti-inflammatory and anti-fibrosis forming role of the slow-release glucocorticoid on the esophageal wound, has a better treatment effect than the conventional self-expanding endoscopic metal stent, shortens the implantation time, and reduces the occurrence risks of complications such as chest pain, gastrointestinal bleeding, granulation tissue hyperplasia, stent displacement and the like of patients.

Drawings

Fig. 1 is a schematic perspective view of a bracket body according to the present utility model;

FIG. 2 is a schematic view of the overall structure of the present utility model;

fig. 3 is an enlarged schematic view of the sieve-shaped side holes on the surface of the small capsule-shaped drug storage bin of the utility model.

Reference numerals in the drawings: 1. a main body bracket; 2. a tubular open end; 3. a first traveling section; 4. an inflow channel; 5. a small saccular drug bin; 6. a second traveling section; 7. an outflow path; 8. a screen-shaped side hole; 9. coating a silica gel film; 10. a slow-release glucocorticoid; 11. and (5) recovering the wire.

Detailed Description

The utility model will be further described with reference to the drawings and embodiments.

Referring to fig. 1, fig. 2 and fig. 3 in combination, fig. 1 is a schematic perspective view of a bracket body according to the present utility model; FIG. 2 is a schematic diagram of the overall structure of the present utility model; FIG. 3 is an enlarged schematic view of the sieve-shaped side holes on the surface of the small capsule-shaped drug warehouse. Comprising the following steps: including main part support 1, the both ends of main part support 1 set up to the slightly big tubular open end 2 of bore, and the one end of main part support 1 is provided with first travelling part 3, and be provided with inflow 4 on the terminal surface of main part support 1 one end, the one end that is close to inflow 4 of tubular open end 2 is equipped with recovery line 11, the other end of main part support 1 is provided with second travelling part 6, and be provided with outflow channel 7 on the terminal surface of main part support 1 other end, all cover on main part support 1, tubular open end 2, first travelling part 3 and the second travelling part 6 has silica gel tectorial membrane 9, the lateral surface of silica gel tectorial membrane 9 is provided with evenly distributed's little saccular medicine storehouse 5, a plurality of evenly distributed's sieve form side openings 8 have been seted up on the surface in little saccular medicine storehouse 5, slowly-releasing glucocorticoid 10 are equipped with in little saccular medicine storehouse 5.

It should be noted that: the quantity and distribution of the slow-release glucocorticoid 10 are controlled by the quantity and distribution of the small saccular drug cabins 5 uniformly distributed on the outer side surface of the silica gel coating film 9, so that the drug distribution is more uniform, the local accumulation of the drug is avoided, the uniformly distributed sieve-shaped side holes 8 uniformly permeate and disperse the slow-release glucocorticoid 10 to the surface of all lesions according to a certain constant speed in a longer time, the anti-inflammatory and anti-fibrosis formation degree of the esophageal wound surface is effectively controlled, the condition that the stenosis caused by the anti-inflammatory and fibrosis formation in the esophageal repair process causes a certain degree of injury to a patient is prevented, the slow-release type hormone drug reaches the esophageal injury part by the local administration of the permeation dispersion principle, the systemic steroid drug is not needed, the possibility of serious complications such as infection, diabetes mellitus, osteoporosis and the like existing in the systemic steroid drug is better solved, the method does not need to locally inject the hormone, the problem of inconsistent reproducibility of local injection and the problem of short duration is effectively solved, and the risk of delayed perforation or wall abscess existing in the local injection is avoided.

Referring to fig. 1 and 2, the main body support 1 is dumbbell-shaped, the main body support 1 is made of titanium-nickel shape memory alloy, the main body support 1 is of a grid-shaped structure, the special titanium-nickel shape memory alloy material is made into a grid cylinder shape, the main body support has a memory function, is self-expanded and expanded after being released to an esophagus injury part, plays continuous mechanical expansion and shaping roles better than the conventional self-expanding endoscope lower metal support in the esophagus wound repair process, and simultaneously stores the slow-release glucocorticoid 10 through the small capsule drug bins 5 with evenly distributed coating outer side surfaces, plays anti-inflammatory and anti-fibrosis forming roles of the slow-release glucocorticoid 10 on esophagus wound surfaces, has better treatment effect than the conventional self-expanding endoscope lower metal support, shortens the implantation time, and reduces the risks of complications such as chest pain, gastrointestinal bleeding, granulation tissue hyperplasia, stent displacement and the like of patients.

The working principle provided by the utility model is as follows: when in use, medical staff performs an operation on a patient, then moves the slow-release hormone medicine self-expanding metal coated film bracket for preventing esophageal stenosis to a proper position, then places the metal bracket in the damaged esophagus of the patient, then the main body bracket 1, the tubular opening end 2 with a slightly larger caliber, the first transitional part 3 and the second transitional part 6 have a memory function, after the slow-release hormone medicine self-expanding metal coated film bracket is released to the damaged part of the esophagus, the slow-release hormone medicine self-expanding metal coated film bracket plays a role of continuous mechanical expansion and shaping in the repairing process of the wound surface of the esophagus, so that the bracket is tightly contacted with the damaged part of the esophagus, and then when the slow-release hormone medicine self-expanding metal coated film bracket is used, body fluid of the wound surface of the esophagus enters the small saccular medicine cabin 5 through the sieve-shaped side holes 8, so that the slow-release glucocorticoid 10 is dissolved, uniformly permeates and disperses to the whole damaged surface from the sieve-shaped side holes 8 according to a certain constant speed, and enters tissues, and plays the role of anti-inflammatory and anti-fibrosis of the glucocorticoid on the wound surface of the esophagus.

The foregoing description is only illustrative of the present utility model and is not intended to limit the scope of the utility model, and all equivalent structures or equivalent processes or direct or indirect application in other related technical fields are included in the scope of the present utility model.

Claims

1. The utility model provides a prevention esophagus stenosis's slowly-releasing hormone medicine is from expanding formula metal tectorial membrane support, includes main part support (1), its characterized in that: the two ends of the main body support (1) are provided with tubular opening ends (2) with slightly larger calibers, one end of the main body support (1) is provided with a first transition part (3), an inflow channel (4) is arranged on the end face of one end of the main body support (1), one end, close to the inflow channel (4), of the tubular opening ends (2) is provided with a recycling line (11), the other end of the main body support (1) is provided with a second transition part (6), the end face of the other end of the main body support (1) is provided with an outflow channel (7), the main body support (1), the tubular opening ends (2), the first transition part (3) and the second transition part (6) are all covered with a silica gel coating (9), the outer side face of the silica gel coating (9) is provided with a small capsule medicine bin (5) which is uniformly distributed, a plurality of sieve-shaped side holes (8) which are uniformly distributed are formed in the surface of the small capsule medicine bin (5), and slow-release glucocorticoids (10) are arranged in the small capsule medicine bin (5).

2. The slow-release hormonal drug self-expanding metal stent graft for preventing esophageal stenosis according to claim 1, wherein the main body stent (1) is dumbbell-shaped.

3. The slow release type hormonal drug self-expanding metal coated stent for preventing esophageal stenosis according to claim 1, wherein the main body stent (1) is made of titanium-nickel shape memory alloy.

4. The slow-release hormonal drug self-expanding metal stent graft for preventing esophageal stenosis according to claim 1, wherein the main body stent (1) is a grid-like structure.