CN218901825U - Reaction device for producing Ruidexivir - Google Patents
Reaction device for producing Ruidexivir Download PDFInfo
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- CN218901825U CN218901825U CN202222189118.6U CN202222189118U CN218901825U CN 218901825 U CN218901825 U CN 218901825U CN 202222189118 U CN202222189118 U CN 202222189118U CN 218901825 U CN218901825 U CN 218901825U
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Abstract
The utility model belongs to the technical field of drug reaction equipment, and discloses a reaction device for producing Rede-Sivir, which has the technical key points that: including the box, fixed mounting has the fixed column between roof and the interior bottom wall in the box, box roof fixedly connected with inlet pipe, the control chamber has been seted up to the fixed column inside, be provided with the rotary mechanism who is located the control chamber in the fixed column, rotary mechanism is including closing plate, lifting unit and water conservancy diversion subassembly, closing plate and control chamber sliding connection, lifting unit, water conservancy diversion subassembly are connected with the closing plate respectively, the fixed column surface is provided with mixing mechanism, mixing mechanism is including puddler, adjusting part and rotary subassembly, multiunit the puddler is annular distribution around the fixed column and is connected with adjusting part, rotary subassembly is located the box inner wall and is connected with the puddler.
Description
Technical Field
The utility model relates to the technical field of drug reaction equipment, in particular to a reaction device for producing Rede-Sivir.
Background
Redox is a nucleoside analog with antiviral activity, having an EC50 value of 74 nM for SARS-CoV and MERS-CoV in HAE cells and 30nM for murine hepatitis virus in delayed brain tumor cells.
The fixed bed reactor is to fill granular solid catalyst or solid reactant inside the reactor to form certain stacked bed layer, and to realize heterogeneous reaction while gas or liquid material flows through the fixed bed layer via the gaps between the grains.
When the existing equipment is used, the solid raw materials and the solution are simply stirred and mixed, and in the reaction process, the raw materials are easy to precipitate and cannot fully react, so that the consumption of the raw materials is increased, and the quality of the generated medicine is poor.
Disclosure of Invention
The present utility model aims to provide a reaction device for producing adefovir, which solves the problems set forth in the background art.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
the utility model provides a reaction unit for producing Ruidexiwei, includes the box, fixed column is fixed mounting between roof and the interior bottom wall in the box, box roof fixedly connected with inlet pipe, the control chamber has been seted up to the fixed column inside, be provided with the rotary mechanism who is located the control intracavity in the fixed column, rotary mechanism is including closing plate, lifting unit and water conservancy diversion subassembly, closing plate and control chamber sliding connection, lifting unit, water conservancy diversion subassembly are connected with the closing plate respectively, the fixed column surface is provided with mixing mechanism, mixing mechanism is including puddler, adjusting part and rotary subassembly, the multiunit the puddler is annular distribution around the fixed column and is connected with adjusting part, rotary subassembly is located the box inner wall and is connected with the puddler.
As a further scheme of the utility model: the lifting assembly comprises a feeding hole which is formed in the bottom end of the side wall of the fixed column and communicated with the control cavity, a discharging hole which is formed in the top end of the side wall of the fixed column and communicated with the control cavity, a threaded rod is rotatably mounted in the control cavity and is in threaded connection with the sealing plate, and the top end of the threaded rod extends out of the box body and is connected with a motor.
As a further scheme of the utility model: the guide assembly comprises a fixed groove with two ends communicated with each other, wherein the two ends of the surface of the sealing plate are provided with the fixed groove, the side wall of the fixed groove is rotatably provided with an adjusting plate matched with the fixed groove, the other side wall of the fixed groove is fixedly provided with a limiting block matched with the adjusting plate, and the limiting block is positioned on the lower side of the adjusting plate.
As a further scheme of the utility model: the adjusting component comprises a sliding ring which is connected with the surface of the fixed column in a sliding manner, the side wall of the sliding ring is rotationally connected with the stirring rod, a traction rope is fixedly connected with the surface of the sliding ring, a pulley is rotationally arranged in the discharging hole, and one end, far away from the sliding ring, of the traction rope penetrates through the discharging hole to be clung to the pulley and is fixedly connected with the sealing plate.
As still further aspects of the utility model: the rotary assembly comprises a rotary fluted disc fixedly connected with one end of the stirring rod, which is far away from the sliding ring, and a vertical rack which is meshed with the rotary fluted disc is fixedly arranged on the inner wall of the box body.
Compared with the prior art, the utility model has the beneficial effects that: through setting up the lifting unit who comprises feed port, discharge port, threaded rod, motor and by fixed slot, regulating plate, stopper constitution water conservancy diversion subassembly mutually supporting, the solution circulation flow of top and interior bottom in the control box that can be convenient has solved current equipment when using, just simple stirring and mixing solid raw materials and solution, in the reaction, the raw materials easily produces the unable abundant reaction of sediment, leads to the consumption of raw materials to increase, the poor problem of the quality of the medicine of production.
Drawings
Fig. 1 is a schematic structural view of a reaction apparatus for producing adefovir.
Fig. 2 is a schematic top view of a stirring rod and its connection structure in a reaction apparatus for producing adefovir.
Fig. 3 is a schematic structural view of a flow guide assembly in a reaction apparatus for producing adefovir.
Wherein: the device comprises a box body 1, a fixed column 2, a feeding pipe 3, a control cavity 4, a circulating mechanism 5, a sealing plate 51, a lifting component 52, a feeding hole 521, a discharging hole 522, a threaded rod 523, a motor 524, a flow guiding component 53, a fixed groove 531, an adjusting plate 532, a limiting block 533, a mixing mechanism 6, a stirring rod 61, an adjusting component 62, a sliding ring 621, a traction rope 622, a pulley 623, a rotating component 63, a rotating fluted disc 631 and a rack 632.
Detailed Description
It should be noted that, without conflict, the embodiments of the present utility model and features of the embodiments may be combined with each other.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art in a specific case.
Specific implementations of the utility model are described in detail below in connection with specific embodiments.
As shown in fig. 1 and fig. 2, a structure diagram of a reaction device for producing reed-solomonseal is provided for an embodiment of the present utility model, which comprises a box body 1, a fixed column 2 is fixedly installed between an inner top wall and an inner bottom wall of the box body 1, a feeding pipe 3 is fixedly connected to the top wall of the box body 1, a control cavity 4 is provided inside the fixed column 2, a rotating mechanism 5 located in the control cavity 4 is provided inside the fixed column 2, the rotating mechanism 5 comprises a sealing plate 51, a lifting component 52 and a flow guiding component 53, the sealing plate 51 is slidably connected with the control cavity 4, the lifting component 52 and the flow guiding component 53 are respectively connected with the sealing plate 51, a mixing mechanism 6 is provided on the surface of the fixed column 2, the mixing mechanism 6 comprises a stirring rod 61, an adjusting component 62 and a rotating component 63, a plurality of stirring rod 61 are annularly distributed around the fixed column 2 and are connected with the adjusting component 62, the rotating component 63 is located on the inner wall of the box body 1 and is connected with the stirring rod 61, in use, raw materials are delivered into the box body 1 through 3, and put into the box body 1, and mixed with the stirring rod 52 in the stirring rod 1, and the stirring rod can be further moved along the direction of the bottom of the stirring rod 52, and the stirring rod can be further moved along the stirring rod 52, and the stirring rod can be conveniently and conveniently moved along the bottom of the stirring rod 3.
As shown in fig. 1, as a preferred embodiment of the present utility model, the lifting assembly 52 includes a feed hole 521 formed at the bottom end of the side wall of the fixed column 2 and communicated with the control chamber 4, a discharge hole 522 formed at the top end of the side wall of the fixed column 2 and communicated with the control chamber 4, a threaded rod 523 is rotatably mounted in the control chamber 4, the threaded rod 523 is in threaded connection with the sealing plate 51, the top end of the threaded rod 523 extends out of the case 1 and is connected with a motor 524, and in use, the motor 524 is started to drive the threaded rod 523 to rotate so as to control the sealing plate 51 to circularly move up and down in the control chamber 4 along the direction of the threaded rod 523, and the solution flows into the control chamber 4 through the feed hole 521 and flows out of the discharge hole 522.
As shown in fig. 1, 2 and 3, as a preferred embodiment of the present utility model, the flow guiding assembly 53 includes a fixing groove 531 with two ends penetrating through the surface of the sealing plate 51, an adjusting plate 532 matched with the fixing groove 531 is rotatably installed on a side wall of the fixing groove 531, a limiting block 533 matched with the adjusting plate 532 is fixedly installed on the other side wall of the fixing groove 531, and the limiting block 533 is located at the lower side of the adjusting plate 532, and in use, through the interaction of the limiting block 533 and the adjusting plate 532, the solution can be controlled to flow in the fixing groove 531 from bottom to top unidirectionally.
As shown in fig. 1 and fig. 2, as a preferred embodiment of the present utility model, the adjusting component 62 includes a sliding ring 621 slidably connected to the surface of the fixed column 2, the side wall of the sliding ring 621 is rotatably connected to the stirring rod 61, a traction rope 622 is fixedly connected to the surface of the sliding ring 621, a pulley 623 is rotatably installed in the discharge hole 522, one end of the traction rope 622, which is far away from the sliding ring 621, passes through the discharge hole 522, is closely attached to the pulley 623 and is fixedly connected to the sealing plate 51, and in use, the sealing plate 51 moves up and down in the control cavity 4, and can pull the sliding ring 621 to move up and down along the direction of the fixed column 2 by cooperating with the traction rope 622, and the sliding ring 621 drives the stirring rod 61 to move up and down in the box 1 to stir and mix the solution.
As shown in fig. 1 and 2, as a preferred embodiment of the present utility model, the rotating assembly 63 includes a rotating fluted disc 631 fixedly connected to an end of the stirring rod 61 away from the sliding ring 621, a rack 632 meshed with the rotating fluted disc 631 is fixedly mounted on an inner wall of the case 1, and in use, the stirring rod 61 moves up and down to drive the stirring rod 61 to rotate through meshing transmission between the rotating fluted disc 631 and the rack 632.
The working principle of the utility model is as follows: when using, throw in the raw materials through inlet pipe 3 to the box 1 in mix with the solution, in mixing process, through lifting unit 52 and water conservancy diversion subassembly 53 mutually support, can be convenient carry the solution circulation of bottom in the box 1 to the box 1 in the top through control chamber 4, effectively avoid the raw materials to produce the sediment, lifting unit 52 and adjusting unit 62 mutually support the control puddler 61 that can be convenient and reciprocate along the direction of fixed column 2 and stir the solution, puddler 61 reciprocates and mutually support with rotating unit 63, can control puddler 61 and rotate simultaneously in the in-process that reciprocates, further improves the stirring effect.
While the preferred embodiments of the present patent have been described in detail, the present patent is not limited to the above embodiments, and various changes may be made without departing from the spirit of the present patent within the knowledge of those skilled in the art.
Claims (5)
1. The utility model provides a reaction unit for producing Ruidexiwei, includes the box, fixed column is fixed mounting between roof and the interior bottom wall in the box, box roof fixedly connected with inlet pipe, its characterized in that, the control chamber has been seted up to the fixed column inside, be provided with the rotary mechanism who is located the control intracavity in the fixed column, rotary mechanism is including closing plate, lifting unit and water conservancy diversion subassembly, closing plate and control chamber sliding connection, lifting unit, water conservancy diversion subassembly are connected with the closing plate respectively, the fixed column surface is provided with mixing mechanism, mixing mechanism is including puddler, adjusting part and rotary part, and the multiunit the puddler is annular distribution around the fixed column and is connected with adjusting part, rotary part is located the box inner wall and is connected with the puddler.
2. The reaction device for producing adefovir in claim 1, wherein the lifting assembly comprises a feed hole which is formed at the bottom end of the side wall of the fixed column and is communicated with the control cavity, a discharge hole which is formed at the top end of the side wall of the fixed column and is communicated with the control cavity, a threaded rod is rotatably mounted in the control cavity and is in threaded connection with the sealing plate, and the top end of the threaded rod extends out of the box and is connected with a motor.
3. The reaction device for producing Ruidexivir according to claim 1, wherein the flow guiding component comprises a fixing groove with two through ends, the surface of the sealing plate is provided with a fixing groove, the side wall of the fixing groove is rotatably provided with an adjusting plate matched with the fixing groove, the other side wall of the fixing groove is fixedly provided with a limiting block matched with the adjusting plate, and the limiting block is positioned on the lower side of the adjusting plate.
4. The reaction device for producing Ruidexivir according to claim 2, wherein the adjusting component comprises a sliding ring with a fixed column surface in sliding connection, the side wall of the sliding ring is rotationally connected with the stirring rod, a traction rope is fixedly connected with the surface of the sliding ring, a pulley is rotatably installed in the discharging hole, and one end of the traction rope, far away from the sliding ring, passes through the discharging hole, clings to the pulley and is fixedly connected with the sealing plate.
5. The reaction device for producing adefovir in accordance with claim 4, wherein the rotating assembly comprises a rotating fluted disc fixedly connected with one end of the stirring rod far away from the sliding ring, and a vertical rack meshed with the rotating fluted disc is fixedly arranged on the inner wall of the box body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222189118.6U CN218901825U (en) | 2022-08-19 | 2022-08-19 | Reaction device for producing Ruidexivir |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222189118.6U CN218901825U (en) | 2022-08-19 | 2022-08-19 | Reaction device for producing Ruidexivir |
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| Publication Number | Publication Date |
|---|---|
| CN218901825U true CN218901825U (en) | 2023-04-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222189118.6U Active CN218901825U (en) | 2022-08-19 | 2022-08-19 | Reaction device for producing Ruidexivir |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116440736A (en) * | 2023-06-12 | 2023-07-18 | 利华益利津炼化有限公司 | Stirring device for petroleum processing |
-
2022
- 2022-08-19 CN CN202222189118.6U patent/CN218901825U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116440736A (en) * | 2023-06-12 | 2023-07-18 | 利华益利津炼化有限公司 | Stirring device for petroleum processing |
| CN116440736B (en) * | 2023-06-12 | 2023-10-31 | 利华益利津炼化有限公司 | Stirring device for petroleum processing |
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