CN218892803U - Kit system capable of being unsealed by machine - Google Patents
Kit system capable of being unsealed by machine Download PDFInfo
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- CN218892803U CN218892803U CN202221026814.9U CN202221026814U CN218892803U CN 218892803 U CN218892803 U CN 218892803U CN 202221026814 U CN202221026814 U CN 202221026814U CN 218892803 U CN218892803 U CN 218892803U
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- sample adding
- sealing layer
- heating
- thermoplastic material
- plate
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- 238000010438 heat treatment Methods 0.000 claims abstract description 85
- 238000007789 sealing Methods 0.000 claims abstract description 82
- 239000012815 thermoplastic material Substances 0.000 claims abstract description 40
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 34
- 239000010410 layer Substances 0.000 claims description 78
- 239000012790 adhesive layer Substances 0.000 claims description 33
- 239000000463 material Substances 0.000 claims description 25
- 238000002844 melting Methods 0.000 claims description 15
- 230000008018 melting Effects 0.000 claims description 15
- 239000000853 adhesive Substances 0.000 claims description 11
- 230000001070 adhesive effect Effects 0.000 claims description 10
- 229920001169 thermoplastic Polymers 0.000 claims description 9
- 229920005989 resin Polymers 0.000 claims description 6
- 239000011347 resin Substances 0.000 claims description 6
- 239000004416 thermosoftening plastic Substances 0.000 claims description 6
- 239000012178 vegetable wax Substances 0.000 claims description 6
- 239000004203 carnauba wax Substances 0.000 claims description 5
- 239000012188 paraffin wax Substances 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000012528 membrane Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 9
- 239000012634 fragment Substances 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 2
- 238000004801 process automation Methods 0.000 abstract 1
- 229920003023 plastic Polymers 0.000 description 8
- 239000004033 plastic Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 7
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- 239000005038 ethylene vinyl acetate Substances 0.000 description 6
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 6
- -1 polyethylene Polymers 0.000 description 6
- 239000004698 Polyethylene Substances 0.000 description 5
- 239000004800 polyvinyl chloride Substances 0.000 description 5
- 229920000915 polyvinyl chloride Polymers 0.000 description 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
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- 239000004743 Polypropylene Substances 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
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- 102000039446 nucleic acids Human genes 0.000 description 2
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- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000004831 Hot glue Substances 0.000 description 1
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- 238000004458 analytical method Methods 0.000 description 1
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- 235000013869 carnauba wax Nutrition 0.000 description 1
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- 229920001187 thermosetting polymer Polymers 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
A machine-openable reagent cartridge system includes a reagent cartridge and a heating plate. And the sealing layer is adhered to the upper surface of the sample adding plate by the thermoplastic material to seal the sample adding hole, so that the reagent in the sample adding hole is ensured not to leak in the moving process. When unsealing, the heating plate heats the thermoplastic material to soften or melt, so that the sealing layer can be removed from the sample adding plate, and the sample adding hole is opened. Compared with the method of sticking a film on a sample adding plate to seal the sample adding hole and manually tearing off the sealing film when in use adopted in the prior art, the reagent kit system of the utility model adopts a thermoplastic material to adhere the sealing layer to the sample adding plate, and the sealing layer is removed by heating and can be automatically completed by a machine. In the existing automatic biochemical instrument, a movable heating device is added, and heating and removing procedures are added, so that the whole-process automation can be realized. And the softened or melted thermoplastic material is not easy to generate fragments or residues, prevents the fragments or residues from falling into the sample adding hole, pollutes the reagent in the sample adding hole, and is cleaner.
Description
Technical Field
The utility model belongs to the technical field of molecular biological experiments, and particularly relates to a kit system capable of being unsealed by a machine.
Background
With the increasing use of biotechnology, more and more manipulations of biological specimens, such as protein/nucleic acid detection or purification, are now rapidly performed using corresponding commercial kits. For example, kits that are common in the market place are: nucleic acid extraction kits, PCR purification kits, elisa kits, chemiluminescent kits, glucose detection kits, and the like.
The kit is usually a sample plate, such as a 48-well plate, a 96-well plate, etc., pre-loaded with the corresponding reagents. At the time of delivery, at least part of the sample application well has added thereto a corresponding reagent, including liquid and/or powder. And then the upper surface is made of a sealing film made of a chemically inert material, usually made of a high polymer plastic material, such as PE (polyethylene) film, PVC (polyvinyl chloride) film and the like, covered and adhered to the orifice of each sample application hole, and the sample application holes are sealed so as to facilitate carrying and transporting the kit, and a layer of aluminum film is additionally adhered outside the sealing film. In use, it is necessary to first tear the top-adhesive seal of the kit, exposing the various ports, allowing loading of the sample/extraction reagent to perform the corresponding biochemical operations.
When the kit is used, the adhered sealing films need to be opened first, and if the kit is used in various automatic biochemical instruments, the openings need to be kept clean, and residual sealing film fragments and/or adhesive cannot exist, so that certain requirements are placed on tearing the sealing films. And the operation of tearing the film is not currently accomplished by machines at low cost. This results in additional time for the operator to perform the film tearing operation during use and to check the cleanliness of the openings after film tearing. If there is a residual substance at the orifice due to, for example, excessive glue, it takes more additional time to clean, and during cleaning, it is also ensured that the residual substance does not fall into the sample application well and contaminate the reagent. This is inconvenient and does not facilitate the purposes of rapid detection and full-automatic operation of the machine.
Accordingly, there is a need for further improvements and enhancements in the art.
Disclosure of Invention
In view of the above-mentioned drawbacks of the prior art, an object of the present utility model is to provide a kit system that can be opened by a machine, so as to shorten the preparation time of the kit before use, and facilitate and rapidly use the kit.
The technical scheme of the utility model is as follows:
the utility model discloses a reagent box system which can be unsealed by a machine, comprising a reagent box and a heating plate; wherein: the kit comprises a sample adding plate and a sealing layer, wherein the sample adding plate is provided with at least one group of sample adding holes with upward openings, and reagents can be contained in the sample adding holes; the sealing layer is adhered to the upper surface of the sample adding plate through an adhesive layer to seal the opening of the sample adding hole; the adhesive layer is made of a thermoplastic material; the bottom surface of the heating plate can be attached to the sealing layer and is used for heating the thermoplastic material to be melted/softened.
The machine-openable reagent kit system of the present utility model comprises a reagent kit and a heating plate. The reagent box comprises a sample adding plate, wherein the opening part of the sample adding hole is arranged on the sample adding plate, and the sample adding hole is sealed by an adhesive layer and an adhesive sealing layer which are made of thermoplastic materials, so that the reagent in the sample adding hole is ensured not to leak in moving. Thermoplastic materials, which are curable at room temperature, tend to soften, even melt, losing their ability to set when the temperature is raised. The heating plate is used to heat the thermoplastic material to melt/soften allowing the sealing layer to be removed. Therefore, before biochemical experiments are carried out, the sealing layer can be removed from the sample adding plate only by softening or melting the thermoplastic material in the adhesive layer through the heating treatment of the heating plate, and the sample adding holes are opened. Compared with the method of sticking a film on a sample adding plate to seal the sample adding hole and manually tearing off the sealing film when in use adopted in the prior art, the kit system of the utility model adopts a thermoplastic material to adhere the sealing layer to the upper surface of the sample adding plate and uses a heating plate to heat for removing. The automatic biochemical device can be completed by machine operation, and in the existing automatic biochemical device, the whole-course automation can be realized by adding a heating plate and adding a heating and moving program for the heating plate. In addition, the softened or melted thermoplastic material is not easy to generate fragments or residues, prevents the fragments or residues from falling into the sample adding hole, pollutes the reagent in the sample adding hole, and is cleaner.
In one embodiment, the kit further comprises a cover layer detachably covering the sealing layer. The cover layer can be similar to a box with one side opened, and is covered on the sealing layer, for example, the side surface of the cover layer is clamped on the side surface of the sample adding plate, and when the kit is used, the cover layer is manually separated and removed, and then the kit is placed in a corresponding biochemical instrument. Typically the cover layer has a certain strength to protect the sealing layer, optionally for example an aluminium shell, a plastic cover with a certain strength, etc. Of course, decorative patterns, instructions, etc. may be added to the cover layer.
Preferably, a heating pipeline is buried inside the heating plate, and the heating pipeline comprises a heating wire or a hot water pipe. Through set up heating pipeline in the inside of hot plate, heat when needs the bottom surface is favorable to real-time control heating and accurate control temperature.
Preferably, the bottom surface comprises an adhesive for adhering the sealing layer; or the bottom surface is provided with an electrode plate, and the electrode plate can be provided with positive/negative charges after being electrified and is used for electrically adsorbing the sealing layer. I.e. the separated sealing layer can be attached to and follow the bottom surface by means of an adhesive or electrostatic action, moving together. Therefore, after the adhesive layer is heated and softened/melted, the sealing layer is directly taken away by the heating plate, and each sample adding hole is completely opened, so that subsequent biochemical operations and the like are conveniently executed.
Preferably, the softening/melting temperature of the thermoplastic material is above room temperature but below 100 ℃. The adhesive layer can not be automatically melted when the adhesive layer is higher than room temperature and ensures that the sealing layer is separated when the adhesive layer is stored and transported and before a common biochemical experiment. And below 100 c, it facilitates heat softening/melting and prevents the addition of Kong Zhongshi agents, such as aqueous solutions, from heat denaturation.
Preferably, the thermoplastic material comprises paraffin wax, vegetable wax or a chemically inert thermoplastic. The common paraffin material is generally solid at the melting temperature of about 60 ℃, has certain hardness and is easy to deform, has certain viscosity, is convenient to bond the sealing layer, is chemically inert to common chemicals in most biochemical reactions, and is not easy to cause chemical reactions, so that the paraffin material is a preferred choice of manufacturing materials of the bonding layer. Whereas the melting point of common vegetable wax materials is substantially 60-90 ℃. In common plastic materials, such as linear high molecular compounds, the thermoplastic plastic is basically thermoplastic, resin molecular chains in the thermoplastic plastic are linear or branched structures, chemical bonds among the molecular chains are not generated, the plastic materials can soften and flow when heated, and harden after cooling, so that the plastic materials have a bonding effect, and the process is a repeatable physical change. It is only necessary to select a common plastic material with a suitable melting/softening temperature, which is between room temperature and 100 degrees celsius, for the adhesive layer, which increases the choice of the adhesive layer material and can be selected according to the actual application range.
More preferably, the vegetable wax is palm wax. Palm wax (Carnauba wax), melting point 80-86 ℃. Has good chemical inertness and does not react with most common reagents. However, the solvents were warm chloroform and warm toluene, only slightly soluble in boiling ethanol (95%), and hardly soluble in water. Therefore, for the kit containing chloroform or toluene, the adhesive layer cannot be made of palm wax.
More preferably, the thermoplastic material is EVA resin. The EVA resin, namely ethylene-vinyl acetate copolymer, (ethylene-vinyl acetate copolymer), has good flexibility and heat sealing performance, and the Vinyl Acetate (VA) content is generally 5% -40%, so that the EVA resin is widely applied to hot melt adhesives. The melting temperature is different according to the VA content, for example EVA220, and the melting point is 87 ℃. In addition, the EVA resin has strong resistance to corrosion of chemicals such as grease, acid, alkali and the like, and can ensure the adhesiveness of the sealing layer and have good resistance to chemical reagents in the sample adding holes by being used as the adhesive layer of the utility model, and is convenient to soften and remove after heating.
Preferably, the sealing layer comprises a sealing film made of a chemically inert material. In this embodiment, the material of the sealing layer and the material of the adhesive layer may be different or the same, so as to increase the selectivity. When a sealing film made of different materials is selected, the sealing film can be made of common plastic materials, such as PE (polyethylene), PP (polypropylene), PVC (polyvinyl chloride) and the like, most of which are common plastic materials, and need not be limited to thermoplastic or thermosetting. Of course, the closure must be sufficiently chemically inert to at least not readily react chemically with the reagents contained in the wells. Of course, a more preferred embodiment is to select the sealing membrane from a material that does not chemically react with the specific chemical reagent in the well.
In another embodiment, the sealing layer may also be made of a thermoplastic material. Wherein the thermoplastic material may be selected to be the same as or different from the thermoplastic material of the adhesive layer. Thus, the sealing material of the upper layer of the template, including the sealing layer and the adhesive layer, is thermoplastic and is melted/softened when heated by the heating plate, thereby facilitating separation and removal after heating. After melting/softening the thermoplastic material, the viscosity increases and adheres better to the higher temperature heating plate.
More preferably, the bottom surface comprises a honeycomb structure or comprises a coating impregnated with the thermoplastic material. Honeycomb structure, has good adsorption capacity, so when the sealing layer and the bonding layer made of thermoplastic materials are melted, the sealing layer and the bonding layer enter into the hole cavity of the honeycomb structure under pressure or are directly adhered by the coating and taken away.
The conception, specific structure, and technical effects of the present utility model will be further described with reference to the accompanying drawings to fully understand the objects, features, and effects of the present utility model.
Drawings
FIG. 1 is a schematic view of the overall structure of a kit system of the present utility model in a ready-to-unseal state;
FIG. 2 is a schematic diagram showing a specific structure of a heating plate according to the present utility model;
FIG. 3 is a flow chart of a method for unsealing a kit according to the present utility model;
in the figure: 1-adding a template; 11-a sample addition hole; 12, a sealing layer; 2-heating plate; 21-heating the pipeline; 22-bottom surface; 23-electrode sheet.
Detailed Description
The utility model provides a kit system which can be unsealed by a machine, and the utility model is further described in detail below with reference to the accompanying drawings and examples for the purpose of making the objects, technical schemes and effects of the utility model clearer and more definite. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.
The machine-openable reagent kit system of the present utility model, the finished product of which is shown in fig. 1, comprises a reagent kit and a heating plate 2. The kit comprises a sample adding plate 1, wherein at least one group of sample adding holes 11 with upward openings are formed in the sample adding plate 1. The template 1 may be a common commercially available template including 96-well plate, 48-well plate, etc., and is not particularly limited. After the sample addition plate 1 has been successfully manufactured or is ready, the corresponding reagents, including liquid and/or powder reagents, can be added to the sample addition well 11. After a predetermined amount of reagent is added, a sealing layer 12 is adhered to the upper surface of the sample application plate 1 via an adhesive layer, and the openings of the respective sample application holes 11 are closed. This avoids spilling the reagents during transport or movement of the kit, or volatilizing the reagents, e.g., aqueous solutions therein, over time.
Wherein the adhesive layer is made of thermoplastic material, and specifically, materials such as paraffin wax, vegetable wax or thermoplastic plastics with chemical inertness can be selected. Only needs to ensure that the adhesive is solid at normal temperature, and plays a role in adhesion; but can soften or melt when heated to the corresponding temperature, and can separate the two bonded objects. The corresponding temperature is typically higher than room temperature but less than 100 degrees because the reagents in the well 11 may be aqueous and may be chemically denatured by too much heat. The application adopts thermoplastic material to make the adhesive layer, forms a solid layer after bonding, will seal layer 12 to the upper surface of application board 1, seals the opening of application plate hole 11. And when the kit is required to be used, the sealing layer 12 can be easily separated by heating the adhesive layer to a melting/softening temperature corresponding to the thermoplastic material used.
Specifically, when the kit is used, the heating plate 2 is attached to the sealing layer 12 from above, and the sealing layer 12 is heated to a heating temperature at which the adhesive layer is melted/softened, so that the adhesive layer below the sealing layer 12 is melted/softened, and the heating plate 1 is released. After separation, the sealing layer 12 is preferably removed following the heating plate 2.
In one embodiment, the heating plate 2 has a specific structure as shown in fig. 2, and includes a bottom surface 22 for adhering to the sealing layer 12. The shape of the bottom surface 22 should be consistent with the shape of the upper surface of the sample adding plate 1, that is, when the heating plate 2 moves and covers the sealing layer 12, each part of the bottom surface 22 should be well adhered to each part of the sealing layer 12, so as to ensure uniform heating of the sealing layer 12, thereby softening or melting the adhesive layer on the other side of the sealing layer 12, and then the heating plate 2 can carry and remove all the sealing layer 12 by means of adhesion or adsorption, so that each sample adding hole 11 is completely opened.
The material of the sealing layer 12 may also be a thermoplastic material, or other materials. If the sealing layer 12 is also made of a thermoplastic material, it is preferable to use a thermoplastic material having the same or a melting point close to that of the adhesive layer, so that the heating temperature of the heating plate 2 is conveniently set. At the time of unsealing, since the thermoplastic material is softened or melted by heating, the viscosity increases, and it is easy to adhere to the bottom surface 22/the sealing layer 12 at a high temperature, and to be removed following the heating plate 2. In order to ensure adhesion of the bottom surface 22 to the thermoplastic material, in a preferred embodiment, the bottom surface 22 further includes a coating that wets the thermoplastic material, thereby further facilitating adhesion of the thermoplastic material. And, more preferably, the bottom surface 22 may further comprise a honeycomb structure, which allows the softened or melted sealing layer 12 to be absorbed and contained in the honeycomb distributed on the bottom surface 22, without any debris or residue, and without causing contamination in the sample application hole 11. Thereby more conveniently adsorbing the thermoplastic material and further ensuring the cleaning of the upper surface of the sample adding plate 1.
If other materials that do not soften/melt easily are used to make the sealing layer 12, such as PE, PVC film, etc., the sealing layer 12 does not melt/soften with the adhesive layer at the heating temperature. In this case, in order to increase the adhesion of the bottom surface 22 to the sealing layer 12, an adhesive, particularly a high-temperature-resistant adhesive, may be disposed on the bottom surface 22, and the sealing layer 12 may be adhered after the adhesion. For example, because the heating temperature is generally within 100 ℃, the high temperature resistant adhesive can be made of PET (Polyethylene terephthalate ) material and can resist 150 ℃ high temperature; and/or, an electrode sheet 23 is provided on the bottom surface 22, preferably on the inner side of the bottom surface 22, and is electrically charged with positive/negative charges, so that the sealing layer 12 is electrically adsorbed after passing through the bottom surface 22 by electrostatic action.
That is, the kit system of the present utility model can be opened by moving the heating plate 2, bonding it to the sealing layer 12, and heating it to melt/soften the thermoplastic material of the adhesive layer. After the kit is placed in the biochemical instrument to be used, the movement and heating of the heating plate 2 may be automatically performed by the biochemical instrument in advance, and the kit may be unsealed. Specifically, it is only necessary to add the heating plate 2 to the biochemical apparatus and add the heating and moving steps of the heating plate 2 to the program, whether the heating plate 2 is moved to the bottom surface 22 to be attached to the sealing layer 12, and then heated; again, heating the heating plate 2 and then moving the heating plate 2 to the bottom surface 22 to attach the sealing layer 12 can be performed by heating, melting/softening the adhesive layer to separate the sealing layer 12. The kit of the present utility model can be fully automated by a machine, and the individual wells 11 can be fully exposed by removing the sealing layer 12, and then can participate in the next biochemical operation.
In summary, as shown in fig. 3, in the machine-openable kit system of the present utility model, the method for unsealing the kit can be summarized as follows: providing a heating plate 2, wherein the bottom surface 22 of the heating plate 2 is matched with the upper surface of the heating plate 1; the unsealing method comprises the following steps:
a. moving the heating plate 2 to the bottom surface 22 to be attached to the sealing layer 12;
b. heating the heating plate 2;
c. the heating plate 2 heats the sealing layer 12 to melt or soften the adhesive layer;
d. the sealing layer 12 and the adhesive layer are moved away from the template 1.
Specifically, in the step a, the moving manner of the heating plate 2 may keep the heating plate 2 parallel to the upper surface of the sample adding plate 1, so that when the reagent kit needs to be unsealed, the heating plate 2 is firstly translated to be right above the reagent kit, and the bottom surface 22 is right opposite to the sealing layer 12; the heating plate 2 is then lowered until the bottom surface 22 is fully adhered to the sealing layer 12.
In step b, the heating mode of the heating plate 2 may be various, for example, the whole heating plate 2 is directly heated by an external heat source, or only the bottom surface 22 is heated; however, as shown in fig. 2, a heating line 21, such as a heating wire or a hot water pipe, is embedded in the heating plate 2 in advance, so that the temperature of the heating plate 2 can be maintained all the time, the bottom surface 22 can be heated only when the reagent cartridge needs to be opened, and the temperature can be easily controlled to be kept constant.
In step c, the heated heating plate 2 penetrates the sealing layer 12, and heats and softens/melts the adhesive layer, or softens/melts the adhesive layer together with the sealing layer 12. In particular depending on whether the material of the sealing layer 12 is also a thermoplastic material.
In step d, the sealing layer 12 and the adhesive layer, preferably jointly attached to the bottom surface 22, follow the movement of the heating plate 2 away from the heating plate 1. Specifically, the method of presetting the adhesive or the electrostatic electrode on the bottom surface 22 can be adopted.
The foregoing describes in detail preferred embodiments of the present utility model. It should be understood that numerous modifications and variations can be made in accordance with the concepts of the utility model by one of ordinary skill in the art without undue burden. Therefore, all technical solutions which can be obtained by logic analysis, reasoning or limited experiments based on the prior art by the person skilled in the art according to the inventive concept shall be within the scope of protection defined by the claims.
Claims (10)
1. A machine-openable kit system, characterized by: comprises a reagent box and a heating plate; wherein: the kit comprises a sample adding plate and a sealing layer, wherein the sample adding plate is provided with at least one group of sample adding holes with upward openings, and reagents can be contained in the sample adding holes; the sealing layer is adhered to the upper surface of the sample adding plate through an adhesive layer to seal the opening of the sample adding hole; the adhesive layer is made of a thermoplastic material;
the bottom surface of the heating plate can be attached to the sealing layer and is used for heating the thermoplastic material to be melted/softened.
2. The kit system according to claim 1, wherein a heating line including a heating wire or a hot water pipe is buried inside the heating plate.
3. The kit system of claim 1, wherein the bottom surface includes an adhesive/electrode tab for adhering/electrically adsorbing the sealing layer.
4. A kit system according to any one of claims 1 to 3, wherein the thermoplastic material has a softening/melting temperature above room temperature but below 100 ℃.
5. A kit system according to any one of claims 1 to 3, wherein the thermoplastic material comprises paraffin wax, vegetable wax or a chemically inert thermoplastic.
6. The kit system of claim 5, wherein the vegetable wax is palm wax.
7. The kit system of claim 5, wherein the thermoplastic is EVA resin.
8. A kit according to any one of claims 1 to 3, wherein the sealing layer comprises a sealing membrane made of a chemically inert material.
9. A kit system according to any one of claims 1 to 3, wherein the sealing layer is made of a thermoplastic material.
10. The kit system of claim 9, wherein the bottom surface comprises a honeycomb structure or comprises a coating impregnated with the thermoplastic material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221026814.9U CN218892803U (en) | 2022-04-30 | 2022-04-30 | Kit system capable of being unsealed by machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221026814.9U CN218892803U (en) | 2022-04-30 | 2022-04-30 | Kit system capable of being unsealed by machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218892803U true CN218892803U (en) | 2023-04-21 |
Family
ID=85995845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221026814.9U Active CN218892803U (en) | 2022-04-30 | 2022-04-30 | Kit system capable of being unsealed by machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218892803U (en) |
-
2022
- 2022-04-30 CN CN202221026814.9U patent/CN218892803U/en active Active
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Effective date of registration: 20231129 Address after: No. 2 Nanya Road, Minhang District, Shanghai, 201321 Patentee after: KANGMA-HEATHCODE (SHANGHAI) BIOTECH Co.,Ltd. Patentee after: Yanshimei Society (Hainan) Medical Beauty Health Technology Co.,Ltd. Address before: Building 12, Lane 118, Furonghua Road, Pudong New Area, Shanghai, 201321 Patentee before: KANGMA-HEATHCODE (SHANGHAI) BIOTECH Co.,Ltd. |