CN218853688U - Cyclodextrin derivative solution concentration device - Google Patents

Abstract

The utility model discloses a cyclodextrin derivative solution enrichment facility, including first concentration mechanism and second concentration mechanism, first concentration mechanism is including setting up at the first jar body at second concentration mechanism top and installing at the internal absorption filtering component and a plurality of filtration membrane element of first jar, the internal a plurality of division boards that are provided with of first jar, the inner chamber of a plurality of division boards with first jar of body is formed with the absorption filter chamber from last to separating in proper order down, deposit the filter chamber, the stock solution chamber, solvent chamber and solution chamber, the absorption filtering component sets up in the absorption filter chamber, deposit the filter chamber and all communicate with absorption filter chamber and stock solution chamber, a plurality of filtration membrane element distribute the setting at the solvent intracavity uniformly, the inlet and the stock solution chamber of filtering the membrane element are linked together, filtration membrane element's solvent export sets up in the solvent intracavity and is linked together with the solvent chamber, the concentrated solution export of filtering the membrane element is linked together with the solution chamber, the solution chamber is linked together with the second concentration mechanism.

Description

Cyclodextrin derivative solution concentration device

Technical Field

The utility model relates to a cyclodextrin technical field especially relates to cyclodextrin derivative solution enrichment facility.

Background

The cyclodextrin derivative is obtained by modifying natural cyclodextrin through molecules, is a series of compounds with excellent performance, and with the continuous development of cyclodextrin and the derivatives thereof, the cyclodextrin derivative is not only applied to the pharmaceutical industry, but also has broad application in the aspects of textile industry, coating industry, environmental protection, agriculture and the like, and particularly the hydroxypropyl and sulfoalkyl ether group cyclodextrin derivative has very wide application in pharmaceutical preparations and is incorporated into multi-national pharmacopoeia. In the prior art, a cyclodextrin derivative needs to be spray-dried by a spray-drying device in a refining process to prepare a finished product. However, because a large amount of solvent is required to be added in the preparation process of the cyclodextrin derivative, before spray drying, the solution containing the cyclodextrin derivative needs to be concentrated firstly and then spray dried, and the traditional concentration treatment mode is to put the solution containing the cyclodextrin derivative into a container to be heated, stirred, evaporated and concentrated.

SUMMERY OF THE UTILITY MODEL

In view of this, the present invention provides a cyclodextrin derivative solution concentrating device to solve the above existing problems.

The utility model provides a technical scheme that its technical problem adopted is:

the utility model provides a cyclodextrin derivative solution enrichment facility, includes first concentrated mechanism and the concentrated mechanism of second, first concentrated mechanism is including setting up the first jar body at the concentrated mechanism top of second and installing absorption filtering component and a plurality of filtration membrane element in the first jar body, the internal a plurality of division boards that are provided with of first jar, a plurality of division boards will the inner chamber of the first jar body is formed with from last to separating in proper order down and adsorbs the filter chamber, deposits filter chamber, stock solution chamber, solvent chamber and solution chamber, it sets up to adsorb filtering component adsorb in the filter chamber, deposit the filter chamber with adsorb the filter chamber with the stock solution chamber all communicates, a plurality of filtration membrane element distribute the setting uniformly in the solvent chamber, the inlet of filtering the membrane element with the stock solution chamber is linked together, filtration membrane element's solvent export set up the solvent intracavity and with the solvent chamber is linked together, filtered concentrated solution export with the solution chamber is linked together, the solution chamber with the concentrated mechanism of second is linked together.

Furthermore, the top of the first tank body is connected with a liquid inlet pipe, and the liquid inlet pipe is communicated with the adsorption and filtration cavity.

Further, the bottom of the cavity wall of the adsorption filtration cavity is provided with a connecting pipe, one end of the connecting pipe penetrates the top of the cavity wall of the sedimentation filtration cavity and extends to the inside of the sedimentation filtration cavity, a filter screen is arranged inside the sedimentation filtration cavity, and the connecting pipe is positioned at one end inside the sedimentation filtration cavity and penetrates the filter screen and extends to the position below the filter screen.

Furthermore, a conveying pipe is connected to the cavity wall of the sedimentation filter cavity, the conveying pipe is arranged above the filter screen, one end of the conveying pipe is connected with the liquid storage cavity, a liquid discharge pipe is further connected to the cavity wall of the sedimentation filter cavity, and the liquid discharge pipe is arranged below the filter screen.

Further, a solvent outlet pipe is connected to the wall of the solvent cavity, a solution outlet pipe is connected to the side wall of the solution cavity, and the solution outlet pipe is communicated with the second concentration mechanism.

Furthermore, the adsorption and filtration assembly comprises a mounting ring arranged on the wall of the adsorption and filtration cavity, a fixing plate arranged in the mounting ring and a plurality of adsorption pieces uniformly distributed on the fixing plate, wherein the fixing plate separates the inner cavity of the mounting ring to form a liquid inlet tank and a liquid outlet tank.

Further, the second is concentrated the mechanism and is included the base, sets up second jar body and mount pad on the base, and install air-blower on the mount pad, first jar body sets up the top of the second jar body, the mount pad is located one side of the second jar body, the air outlet of air-blower passes the lateral wall of the second jar body extends to in the second jar body.

Further, the mounting panel is installed at the inner chamber top of the second jar of body, install the shower head on the mounting panel, the one end of solution exit tube is passed the lateral wall of the second jar of body extends to in the second jar of body and with the shower head is connected.

Further, the air-blower is including installing casing on the mount pad, rotationally install the wind wheel in the casing, install be close to the heating wire of air outlet department in the casing, and install be close to the controller of air outlet department outside the casing, the air-blower is including installing casing on the mount pad, rotationally install the wind wheel in the casing, install in the casing is close to the heating wire of air outlet department, and install the casing.

Further, the air blower also comprises a driving motor installed on the shell, and the driving motor is in transmission connection with the wind wheel.

The utility model has the advantages that:

the utility model provides a pair of cyclodextrin derivative solution enrichment facility includes first concentrated mechanism and the concentrated mechanism of second, first concentrated mechanism includes the first jar of body and installs absorption filter assembly and a plurality of filtration membrane element in the first jar of body, the internal a plurality of division boards that are provided with of first jar, the inner chamber of a plurality of division boards with the first jar of body is from last to separating in proper order down and being formed with the absorption filter chamber, deposit the filter chamber, the stock solution chamber, solvent chamber and solution chamber, absorption filter assembly sets up in the absorption filter chamber, deposit the filter chamber and adsorb filter chamber and stock solution chamber and all communicate, a plurality of filtration membrane element distribute uniformly and set up in the solvent intracavity, the inlet and the stock solution chamber of filtration membrane element are linked together, filtration membrane element's solvent export sets up and is linked together at the solvent intracavity and with the solvent chamber, the concentrated solution export of filtration membrane element is linked together with the solution chamber, the solution chamber is linked together with the concentrated mechanism of second, cyclodextrin derivative solution can effectively reduce the impurity in the cyclodextrin derivative solution through depositing the filtration filter chamber deposit after the processing of the concentrated solution of precipitation, thereby the concentrated solution produces concentrated solution and the effectual concentrated mechanism of second concentration drying and the concentration mechanism of drying that carry out air blast through the follow-up and carry out the effectual concentrated mechanism, thereby the concentrated cyclodextrin concentration efficiency of the concentrated cyclodextrin is improved.

Drawings

The present invention will be further explained with reference to the drawings and examples.

Fig. 1 is a front view of a cyclodextrin derivative solution concentrating apparatus of the present invention;

fig. 2 is a sectional view of the cyclodextrin derivative solution concentrating device of the present invention shown in fig. 1.

FIG. 3 is a cross-sectional view of the adsorption filtration module of the cyclodextrin derivative solution concentration apparatus of the present invention shown in FIG. 2;

fig. 4 is a sectional view of a blower in the cyclodextrin derivative solution concentrating apparatus of the present invention shown in fig. 2.

In the figure: 100. cyclodextrin derivative solution concentration device, 1, a first concentration mechanism, 11, a first tank body, 111, an adsorption filtration cavity, 1111, a connecting pipe, 112, a precipitation filtration cavity, 1121, a filter screen, 1122, a conveying pipe, 1123, a liquid discharge pipe, 113, a liquid storage cavity, 114, a solvent cavity, 1141, a solvent outlet pipe, 115, a solution cavity, 1151, a solution outlet pipe, 12, a liquid inlet pipe, 13, a partition plate, 14, an adsorption filtration assembly, 141, a mounting ring, 1411, a liquid inlet tank, 1412, a liquid outlet tank, 142, a fixing plate, 143, an adsorption piece, 15, a filtration membrane element, 2, a second concentration mechanism, 21, a base, 22, a second tank body, 221, a mounting plate, 222, a spray head, 223, a liquid outlet pipe, 23, a mounting seat, 24, a blower, 241, a shell, 242, a wind wheel, 243, an electric heating wire, 244 and a controller.

Detailed Description

The present invention will now be described in detail with reference to the accompanying drawings. This figure is a simplified schematic diagram, and merely illustrates the basic structure of the present invention in a schematic manner, and therefore it shows only the constitution related to the present invention.

As shown in fig. 1, the utility model provides a cyclodextrin derivative solution enrichment facility 100 for concentrated cyclodextrin derivative solution, cyclodextrin derivative solution enrichment facility 100 includes first concentration mechanism 1 and second concentration mechanism 2, first concentration mechanism 1 sets up and is linked together at the top of second concentration mechanism 2 and first concentration mechanism 1 and second concentration mechanism 2, cyclodextrin derivative solution carries out the membrane separation concentration through first concentration mechanism 1 in getting into first concentration mechanism 1 and obtains concentrated solution in order to separate out partial solvent, concentrated solution carries again to handle in second concentration mechanism 2 through subsequent spray drying after heating concentration in order to obtain cyclodextrin derivative.

As shown in fig. 1 and fig. 2, the first concentration mechanism 1 includes a first tank 11, an adsorption filtration module 14 and a plurality of filtration membrane elements 15 installed in the first tank, a liquid inlet pipe 12 is connected to a top of the first tank 11, a plurality of partitions 13 for partitioning an inner cavity of the first tank 11 are fixedly installed inside the first tank 11, the inner cavity of the first tank 11 is sequentially partitioned from top to bottom by the plurality of partitions 13 to form an adsorption filtration cavity 111 for adsorbing and filtering cyclodextrin derivative solution, a precipitation filtration cavity 112 for depositing and filtering cyclodextrin derivative solution, a liquid storage cavity 113 for storing filtered cyclodextrin derivative solution, a solvent cavity 114 for containing solvent, and a solution cavity 115 for containing concentrated solution, wherein the liquid inlet pipe 12 is communicated with the adsorption filtration cavity 111, the adsorption filtration module 14 is installed in the adsorption filtration cavity 111, a connection pipe 1111 for conveying cyclodextrin derivative solution after adsorption and filtration is installed at a bottom of the wall of the adsorption filtration cavity 111, one end of the connection pipe 1111 extends into the precipitation filtration cavity 112 through a top wall of the precipitation filtration cavity 112, the precipitation filtration cavity 112 is provided with a discharge pipe 1122 for discharging cyclodextrin derivative solution from a lower portion of the precipitation filtration cavity 112, and a discharge pipe 1121 is connected to a discharge pipe 1122 for discharging a discharge filter 112 for discharging cyclodextrin derivative solution from a lower end of the precipitation filtration cavity 112, the multiple filtering membrane elements 15 are uniformly distributed in the solvent cavity 114, a liquid inlet of each filtering membrane element 15 is communicated with the liquid storage cavity 113, a solvent outlet of each filtering membrane element 15 is arranged in the solvent cavity 114 and communicated with the solvent cavity 114, a solvent outlet pipe 1141 for discharging a solvent is connected to the cavity wall of the solvent cavity 114, a concentrated solution outlet of each filtering membrane element 15 is communicated with the solution cavity 115, a solution outlet pipe 1151 for conveying a concentrated solution is connected to the side wall of the solution cavity 115, the solution outlet pipe 1151 is communicated with the second concentrating mechanism 2, a cyclodextrin derivative solution in the liquid storage cavity 113 enters the filtering membrane element 15 through the liquid inlet of the filtering membrane element 15 for membrane separation, the separated solvent is discharged through the solvent outlet of the filtering membrane element 15 and conveyed into the solvent cavity 114 and discharged through the solvent outlet pipe 1141 for collection and reuse, the separated concentrated solution is conveyed into the solution cavity 115 through the solution outlet of the filtering membrane element 15 and conveyed into the second concentrating mechanism 2 through the solution outlet pipe 1 for secondary concentration treatment, in the embodiment, the four filtering membrane elements 15 are all four membrane elements, and the four filtering membrane elements are reverse osmosis membrane elements, and at least one of the microfiltration membrane elements and the microfiltration membrane element 115.

As shown in fig. 1, fig. 2 and fig. 3, the adsorption filter assembly 14 includes an installation ring 141 installed on the wall of the adsorption filter cavity 111, a fixing plate 142 disposed in the installation ring 141, and a plurality of adsorption members 143 uniformly distributed on the fixing plate 142, the fixing plate 142 partitions the inner cavity of the installation ring 141 into a liquid inlet 1411 and a liquid outlet 1412, the cyclodextrin derivative solution is delivered into the adsorption filter cavity 111 through a liquid inlet pipe 12 and then flows into the liquid inlet 1411 on the installation ring 141 to contact with the adsorption members 143, and the cyclodextrin derivative solution passing through the adsorption members 143 is adsorbed and filtered by the adsorption members 143 and then flows out through the liquid outlet 1412, in this embodiment, the adsorption members 143 are made of activated carbon.

As shown in fig. 1, 2 and 4, the second concentrating mechanism 2 includes a base 21, a second tank 22 and a mounting seat 23 disposed on the base 21, and a blower 24 mounted on the mounting seat 23, the first tank 11 of the first concentrating mechanism 1 is disposed on top of the second tank 22, the mounting seat 23 is located on one side of the second tank 22, an air outlet of the blower 24 extends into the second tank 22 through a sidewall of the second tank 22, a mounting plate 221 is mounted on top of an inner cavity of the second tank 22, a spray head 222 for spraying concentrated solution is mounted on the mounting plate 221, one end of a solution outlet pipe 1151 extends into the second tank 22 through a sidewall of the second tank 22 and is connected to the spray head 222, the blower 24 includes a housing 241 mounted on the mounting seat 23, a wind wheel 242 rotatably mounted in the housing 241, a heating wire 243 mounted in the housing 241 near the air outlet for heating, and a controller 244 mounted outside the housing near the air outlet for controlling the heating wire 243, the housing and further includes a driving motor (not shown) mounted on the housing 241, the driving motor is connected to the wind wheel, the first concentrating motor is connected to the first concentrating mechanism 1, and heats the concentrated solution through the spray head 22 and then flows into the second tank 22, the concentrated solution is heated by the second concentrated solution outlet pipe 242, and flows into the concentrated solution sprayed into the second tank 22, when the concentrated solution outlet pipe 22, and then flows into the concentrated solution is heated concentrated solution outlet pipe 242.

When the device is used, a cyclodextrin derivative solution is conveyed into the first tank body 11 through the liquid inlet pipe 12, the cyclodextrin derivative solution is conveyed into the adsorption and filtration cavity 111 through the liquid inlet pipe 12 and then flows into the liquid inlet groove 1411 on the installation ring 141 to be contacted with the adsorption piece 143, the cyclodextrin derivative solution passing through the adsorption piece 143 is adsorbed and filtered and then flows out through the liquid outlet groove 1412, the filtered cyclodextrin derivative solution is conveyed into the precipitation and filtration cavity 112 through the connecting pipe 1111 to be kept standing and deposited, the deposited cyclodextrin derivative solution is conveyed into the liquid storage cavity 113 through the conveying pipe 1122 to be concentrated and treated, the deposited waste liquid is discharged out of the precipitation and filtration cavity 112 through the liquid outlet pipe 1123 to be recycled, the cyclodextrin derivative solution entering the liquid storage cavity 113 enters the filtration membrane element 15 through the liquid inlet of the filtration membrane element 15 to be subjected to membrane separation, the separated solvent is discharged out of the solvent outlet on the filtration membrane element 15 and conveyed into the solvent cavity 243 through the solvent outlet pipe 1141 to be collected and reused, the separated concentrated solution is conveyed into the solution cavity 115 through the solvent outlet pipe 1151 to be sprayed into the second tank body 24 to be heated and sprayed into the air flow head 242 to be heated and sprayed into the second electric heating wire 242.

The utility model provides a pair of cyclodextrin derivative solution enrichment facility 100 includes first concentrated mechanism 1 and the concentrated mechanism 2 of second, first concentrated mechanism 1 includes first jar of body 11 and installs absorption filter assembly 14 and a plurality of filtration membrane element 15 in first jar of body, be provided with a plurality of division boards 13 in the first jar of body 11, a plurality of division boards 13 are formed with absorption filter chamber 111 with the inner chamber of first jar of body 11 from last to separating in proper order down, deposit filter chamber 112, stock solution chamber 113, a solvent chamber 114 and solution chamber 115 for holding the solvent, absorption filter assembly 13 sets up in absorption filter chamber 111, deposit filter chamber 112 and absorption filter chamber 111 and stock solution chamber 113 all communicate, a plurality of filtration membrane element 15 distribute uniformly and set up in solvent chamber 114, filtration membrane element 15's inlet is linked together with stock solution chamber 113, filtration membrane element 15's solvent export sets up in solvent chamber 114 and is linked together with solvent chamber 114, filtration membrane element 15's concentrated solution export is linked together with solution chamber 115, solution chamber 115 is linked together with second concentrated mechanism 2 is linked together, cyclodextrin derivative is filtered through the precipitation filter assembly 14 after-pass through the effective concentrated solvent that the precipitation filter assembly 112 and the effective concentration solvent that the air-spray concentration solution that can reduce the concentrated solution that the concentrated mechanism carries out the concentrated solution of the concentrated mechanism and the concentrated solution of the concentrated mechanism's concentration of the concentration after-concentrating that the concentration of the effective cyclodextrin that the dry process that the cyclodextrin is carried out the drying process of the cyclodextrin is carried out.

In light of the foregoing, it will be apparent to those skilled in the art from this disclosure that various changes and modifications can be made without departing from the scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.

Claims (10)

1. The utility model provides a cyclodextrin derivative solution enrichment facility, a serial communication port, including first concentrated mechanism and the concentrated mechanism of second, first concentrated mechanism is including setting up the first jar body at the concentrated mechanism top of second and installing absorption filtering component and a plurality of filtration membrane element in the first jar body, the internal a plurality of division boards that are provided with of first jar, a plurality of division boards will the inner chamber of the first jar body is from last to separating in proper order down and being formed with absorption filtering cavity, sediment filtering cavity, stock solution chamber, solvent chamber and solution chamber, absorption filtering component sets up in the absorption filtering cavity, sediment filtering cavity with absorption filtering cavity with the stock solution chamber all communicates, a plurality of filtration membrane element distribute the setting uniformly in the solvent intracavity, the inlet of filtering membrane element with the stock solution chamber is linked together, filtration membrane element's solvent export set up the solvent intracavity and with the solvent chamber is linked together, the concentrated solution export of filtering membrane element with the solution chamber is linked together, the solution chamber with the concentrated mechanism of second is linked together.

2. The cyclodextrin derivative solution concentrating apparatus of claim 1, wherein a liquid inlet pipe is connected to the top of the first tank, and the liquid inlet pipe is communicated with the adsorption filtration chamber.

3. The cyclodextrin derivative solution concentration device of claim 1, wherein a connecting pipe is arranged at the bottom of the cavity wall of the adsorption filtration cavity, one end of the connecting pipe passes through the top of the cavity wall of the precipitation filtration cavity and extends into the precipitation filtration cavity, a filter screen is arranged inside the precipitation filtration cavity, and one end of the connecting pipe, which is positioned in the precipitation filtration cavity, passes through the filter screen and extends below the filter screen.

4. The cyclodextrin derivative solution concentration device of claim 3, wherein the wall of the precipitation filtration chamber is connected with a delivery pipe, the delivery pipe is disposed above the filter screen, one end of the delivery pipe is connected with the liquid storage chamber, the wall of the precipitation filtration chamber is further connected with a drain pipe, and the drain pipe is disposed below the filter screen.

5. The cyclodextrin derivative solution concentrating device according to claim 1, wherein a solvent outlet pipe is connected to a wall of the solvent chamber, and a solution outlet pipe is connected to a sidewall of the solution chamber, and the solution outlet pipe is communicated with the second concentrating mechanism.

6. The cyclodextrin derivative solution concentrating apparatus of claim 1, wherein the adsorption filter assembly comprises a mounting ring mounted on the wall of the adsorption filter chamber, a fixing plate disposed in the mounting ring, and a plurality of adsorption members uniformly distributed on the fixing plate, wherein the fixing plate divides the inner cavity of the mounting ring into a liquid inlet tank and a liquid outlet tank.

7. The cyclodextrin derivative solution concentration device of claim 5, wherein the second concentration mechanism comprises a base, a second tank and a mounting seat disposed on the base, and a blower mounted on the mounting seat, wherein the first tank is disposed on top of the second tank, the mounting seat is located at one side of the second tank, and an air outlet of the blower extends into the second tank through a sidewall of the second tank.

8. The cyclodextrin derivative solution concentrating apparatus of claim 7, wherein a mounting plate is installed at a top of the inner cavity of the second tank, a shower head is installed on the mounting plate, and one end of the solution outlet pipe extends into the second tank through a sidewall of the second tank and is connected to the shower head.

9. The cyclodextrin derivative solution concentrating apparatus of claim 7, wherein the blower comprises a housing mounted to the mounting base, a wind wheel rotatably mounted in the housing, a heating wire mounted in the housing near the air outlet, and a controller mounted outside the housing near the air outlet.

10. The cyclodextrin derivative solution concentrating device of claim 9, wherein the blower further comprises a drive motor mounted on the housing, the drive motor being drivingly connected to the wind wheel.

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