CN218833295U - Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index - Google Patents

Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index Download PDF

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Publication number
CN218833295U
CN218833295U CN202222034321.6U CN202222034321U CN218833295U CN 218833295 U CN218833295 U CN 218833295U CN 202222034321 U CN202222034321 U CN 202222034321U CN 218833295 U CN218833295 U CN 218833295U
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China
Prior art keywords
base
chip
catheter
gland
medicine
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CN202222034321.6U
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Chinese (zh)
Inventor
许佳润
陈旭东
王富玉
吕孔鹏
李明
王文刚
徐政和
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Shenzhen Liankehanwei Medical Technology Co ltd
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Shenzhen Liankehanwei Medical Technology Co ltd
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Abstract

The utility model discloses a chip medicine box for monitoring the medicine concentration and biochemical index in vivo in real time, which comprises a gland, a base, a puncture diaphragm and a catheter; the gland is arranged on the base, one end of the base is provided with an extension part, and one end of the guide pipe is connected with the extension part; a step is arranged in the base, a through hole is arranged on the gland, one end of the puncture diaphragm covers the step, and the other end of the puncture diaphragm is arranged in the through hole; a cavity is formed between the base and the puncture diaphragm; a chip is arranged on the inner wall of the conduit and is in wireless connection with external electronic equipment; the chip is used for detecting the concentration of a specific medicine in the medicine box and transmitting data to external electronic equipment; medical staff can know the concentration of the medicine in the medicine box through external electronic equipment; the connection of the gland and the base adopts an ultrasonic welding process method, so that the leakage is not easy to occur, no adhesive is used, the firmness is more reliable, the leakage-proof performance is more perfect, and the yield is greatly improved; the conduit is easy to fix, install and operate.

Description

Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a chip medicine box of internal drug concentration of real-time supervision and biochemical index.
Background
The medical internal implanted medicine box is a multifunctional medicine box which is embedded under the skin and used for locally filling medicines or delivering nutrition; a large number of scientific researches and long-term clinical practices prove that the in-vivo embedded implantation drug delivery is the best choice for targeted therapy of tumor patients; the device can be implanted into body for repeated percutaneous directional perfusion of medicine, and can be used for directional chemotherapy for cancer and directional local perfusion chemotherapy for preventing recurrence after tumor resection; the liquid medicine can directly enter the set part through the medicine pump and the catheter, so that the concentration of the local medicine of the pathological change part is greatly increased, and the killing power and the curative effect on cancer cells are improved; the toxic and side effects of chemotherapy are reduced; however, the existing in vivo implantable drug box can not monitor the drug concentration of the specific drug in the drug box, which brings great inconvenience.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the defects existing in the prior art and providing a chip medicine box for monitoring the medicine concentration and biochemical indexes in vivo in real time.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a chip medicine box for real-time monitoring of medicine concentration and biochemical index in vivo comprises a gland, a base, a puncture diaphragm and a catheter; the gland is arranged on the base, one end of the base is provided with an extension part, and one end of the guide pipe is connected with the extension part; a step is arranged in the base, a through hole is arranged on the gland, one end of the puncture diaphragm covers the step, and the other end of the puncture diaphragm is arranged in the through hole; a cavity is formed between the base and the puncture diaphragm; the inner wall of the conduit is provided with a chip, and the chip is in wireless connection with external electronic equipment.
Preferably, a channel is arranged in the extension part, a steel needle is arranged in the channel, one end of the steel needle is communicated with the cavity, and the other end of the steel needle is tightly sleeved with the catheter.
Preferably, the outer wall of the extension part is provided with a bulge close to the base, and a plurality of first grooves are uniformly distributed in the middle section of the extension part.
Preferably, a catheter lock is arranged on the catheter, and the catheter lock is sleeved at one end of the catheter.
Preferably, a second groove is formed on the inner wall of the catheter lock corresponding to the position of the protrusion on the outer wall of the extension part.
Preferably, the catheter lock tip is provided with a radiopaque ring.
Preferably, a plurality of palpation points are arranged on the puncture diaphragm in a surrounding manner.
Preferably, the catheter is a valve catheter.
Preferably, three sewing holes are uniformly distributed at the edge of the base.
Preferably, the end face of the base is circular, the top surface of the puncture diaphragm is spherical, and the top surface of the puncture diaphragm is higher than the top surface of the gland or lower than the top surface of the gland.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model relates to a chip medicine box for monitoring the medicine concentration and biochemical index in vivo in real time, wherein erythrocytes in the body of a patient generate tiny current to supply power to the chip, and the chip is used for detecting the specific medicine concentration in the medicine box and transmitting data to external electronic equipment; medical staff can know the concentration of the medicine in the medicine box through external electronic equipment; the connection of the gland and the base adopts an ultrasonic welding process method, so that the leakage is not easy to occur, no adhesive is used, the firmness is more reliable, the leakage-proof performance is more perfect, and the yield is greatly improved; aligning the extension on the base with the catheter, pushing the catheter along the extension just beyond the raised portion on the extension, pushing the catheter lock along a straight line, ensuring that the black, radiopaque ring at the tip of the catheter lock is distal to the extension; the fixing is easy, the installation and the operation are convenient, the positioning is stable after the fixing is placed, and the foreign body feeling is light; the design of the model is not only beautiful and exquisite, but also more convenient for the direction and the positioning when being implanted, and is suitable for various cancer-oriented chemotherapies, targeted therapies and regional perfusion chemotherapies for preventing relapse after tumor resection; the infection chance of the patient is reduced, the self-care of the patient is not needed, the traffic and time cost for the patient to see a doctor is reduced, and the vein of the patient is protected.
Drawings
FIG. 1 is a schematic diagram of the present invention;
fig. 2 is a diagram showing a state in which the base and the duct are separated from each other according to the present invention;
fig. 3 is a cross-sectional view of the present invention.
Illustration of the drawings:
1. a gland 2 and a base, wherein the gland is arranged on the base,
3. a puncture membrane, 4, a catheter,
5. the extension part (6) is arranged in the cavity,
7. a chip, 8, a conduit lock,
9. a radiopaque ring, 11, a through hole,
21. a step, 22, a sewing hole,
31. the palpation point, 51, the steel needle,
52. the protrusions, 53, the first grooves,
81. a second groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance; furthermore, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, as they may be fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood as a specific case by those skilled in the art.
Referring to fig. 1 to 3, a chip medicine box for real-time monitoring of in vivo drug concentration and biochemical index comprises a gland 1, a base 2, a puncture diaphragm 3 and a catheter 4; the gland 1 is arranged on the base 2, one end of the base 2 is provided with an extension part 5, and one end of the conduit 4 is connected with the extension part 5; a step 21 is arranged in the base 2, a through hole 11 is arranged on the gland 1, one end of the puncture diaphragm 3 covers the step 21, and the other end of the puncture diaphragm 3 is arranged in the through hole 11; a cavity 6 is formed between the base 2 and the puncture diaphragm 3; a chip 7 is arranged on the inner wall of the conduit 4, and the chip 7 is wirelessly connected with external electronic equipment; red blood cells in a patient body generate micro current to supply power to the chip 7, and the chip 7 is used for detecting the concentration of a specific medicine in the medicine box and transmitting data to external electronic equipment; the medical staff can know the concentration of the medicine in the medicine box through the external electronic equipment.
Wherein, a channel is arranged in the extension part 5, a steel needle 51 is arranged in the channel, one end of the steel needle 51 is communicated with the cavity 6, and the other end of the steel needle 51 is tightly sleeved with the catheter 4; the base 2 and the extension part 5 are integrally formed, the connection of the gland 1 and the base 2 adopts an ultrasonic welding process method, the leakage is not easy, no adhesive is used, the firmness is more reliable, the leakage-proof performance is more perfect, and the yield is greatly improved; a bulge 52 is arranged on the outer wall of the extension part 5 close to the base, and a plurality of first grooves 53 are uniformly distributed in the middle section of the extension part 5; the catheter 4 is provided with a catheter lock 8 which can easily fix the catheter 4; the catheter lock 8 is sleeved at one end of the catheter 4; a second groove 81 is arranged on the inner wall of the catheter lock 8 corresponding to the position of the protrusion 52 on the outer wall of the extension part 5; the extension part 5 and the catheter lock 8 are fixedly connected through the protrusion 52 and the second groove 81.
The distal end of the catheter lock 8 is provided with a radiopaque ring 9 to ensure correct visualization of the connected catheter lock 8; a plurality of palpation points 31 are arranged on the puncture diaphragm 3 in a surrounding way, so that palpation and identification of a high-pressure resistant device are facilitated; the catheter 4 is a valve catheter, which helps to prevent blood reflux and air embolism in the port/catheter system; compared with the end opening type catheter, the maintenance interval period is 3 times as long as 90 days; helps prevent blood reflux and air embolism in the port/catheter system, flushes the catheter 4 with saline, and does not require heparin to maintain patency; when the valve catheter 4 is under negative pressure, the valve is opened inwards, and blood can be drawn; when the pressure is positive, the valve is opened outwards, and infusion can be carried out; during balancing, the valve is closed, and the risk of air embolism, blood backflow or coagulation is avoided.
Three sewing holes 22 are uniformly distributed at the edge of the base 2, so that a placer can sew the chip medicine box in place according to the preference of the placer; the end surface of the base 2 is round, the top surface of the puncture diaphragm 3 is spherical, and the top surface of the puncture diaphragm 3 is higher than the top surface of the gland 1 or lower than the top surface of the gland 1; the sealing performance between the puncture diaphragm 3 and the base 2 is better, the fixed combination of the conduit 4 and the extension part 5 is firmer, the use safety is more reliable, the front end of the gland 1 is slightly pointed, the periphery can be inserted into subcutaneous tissues more easily during the operation implantation operation along the flat and thin streamline design, the position of the conduit 4 can be determined more easily by utilizing the design that the front end and the rear end can be distinguished obviously, and the integral performance is ideal.
Aligning the extension 5 on the base 2 with the catheter 4, pushing the catheter 4 along the extension 5 just beyond the protrusion 52 on the extension 5, pushing the catheter lock 8 in a straight line, ensuring that the black, radiopaque ring 9 on the end of the catheter lock 8 is distal to the extension 5; the fixing is easy, the installation and the operation are convenient, the positioning is stable after the fixing is placed, and the foreign body feeling is light; the design of the model is beautiful and exquisite, is more convenient for the direction and the positioning during the implantation, and is suitable for the targeted chemotherapy of various cancers, the targeted therapy and the regional perfusion chemotherapy for preventing the recurrence after the tumor resection; the infection chance of the patient is reduced, the self-care of the patient is not needed, the traffic and time cost for the patient to see a doctor is reduced, and the vein of the patient is protected.
Above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the design of the present invention, equivalent replacement or change should be covered within the protection scope of the present invention.

Claims (10)

1. A chip medicine box for monitoring the concentration of medicine and biochemical index in vivo in real time is characterized by comprising a gland, a base, a puncture diaphragm and a catheter; the gland is arranged on the base, one end of the base is provided with an extension part, and one end of the guide pipe is connected with the extension part; a step is arranged in the base, a through hole is arranged on the gland, one end of the puncture diaphragm covers the step, and the other end of the puncture diaphragm is arranged in the through hole; a cavity is formed between the base and the puncture diaphragm; the inner wall of the conduit is provided with a chip, and the chip is in wireless connection with external electronic equipment.
2. The chip medicine box for real-time monitoring of in vivo drug concentration and biochemical indicator according to claim 1, wherein a channel is provided in the extension portion, a steel needle is provided inside the channel, one end of the steel needle is communicated with the cavity, and the other end of the steel needle is tightly sleeved with the catheter.
3. The chip kit for real-time monitoring of in vivo drug concentration and biochemical indicator according to claim 2, wherein the extension has a protrusion on its outer wall near the base, and a plurality of first grooves are uniformly distributed on the middle section of the extension.
4. The kit as claimed in claim 3, wherein the catheter lock is disposed on the catheter and the catheter lock is sleeved on one end of the catheter.
5. The kit as claimed in claim 4, wherein a second groove is formed on the inner wall of the catheter lock at a position corresponding to the protrusion on the outer wall of the extension portion.
6. The device of claim 4, wherein the catheter lock is configured with a radiopaque ring at the distal end thereof.
7. The kit according to claim 1, wherein the plurality of palpation sites are disposed around the puncture membrane.
8. The kit of claim 1, wherein the conduit is a valve conduit.
9. The chip kit for real-time monitoring of in vivo drug concentration and biochemical indicator according to claim 1, wherein three suture holes are uniformly distributed on the edge of the base.
10. The kit of claim 1, wherein the end of the base is circular, the top surface of the puncturing septum is spherical, and the top surface of the puncturing septum is higher than or lower than the top surface of the gland.
CN202222034321.6U 2022-08-03 2022-08-03 Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index Active CN218833295U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222034321.6U CN218833295U (en) 2022-08-03 2022-08-03 Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222034321.6U CN218833295U (en) 2022-08-03 2022-08-03 Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index

Publications (1)

Publication Number Publication Date
CN218833295U true CN218833295U (en) 2023-04-11

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ID=87292505

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222034321.6U Active CN218833295U (en) 2022-08-03 2022-08-03 Chip medicine box for real-time monitoring in-vivo medicine concentration and biochemical index

Country Status (1)

Country Link
CN (1) CN218833295U (en)

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