CN218826957U

CN218826957U - Ionization source structure and detection equipment

Info

Publication number: CN218826957U
Application number: CN202222215096.6U
Authority: CN
Inventors: 封荣贵; 杜绪兵; 苏亮; 许春华
Original assignee: Guangzhou Hexin Instrument Co Ltd
Current assignee: Guangzhou Hexin Instrument Co Ltd
Priority date: 2022-08-22
Filing date: 2022-08-22
Publication date: 2023-04-07
Anticipated expiration: 2032-08-22

Abstract

The utility model relates to an ionization source structure and check out test set, check out test set include ionization source structure and main part. The ionization source structure comprises an installation part and an adjusting component, wherein the installation part is used for installing detection equipment, an ionization cavity is formed in the installation part, a sample injection channel communicated with the ionization cavity is arranged on the installation part in a penetrating mode, a penetrating hole is further formed in the installation part and communicated with the sample injection channel, and the central axis of the penetrating hole is intersected with the central axis of the sample injection channel; the adjusting component can be movably arranged on the mounting component, an adjusting hole is formed in the adjusting component and communicated with the penetrating hole, and the adjusting hole is used for penetrating the electric spray needle and enabling one end of the electric spray needle to penetrate through the penetrating hole to be located in the ionization cavity. When the position of the electrospray needle needs to be adjusted, the position of the adjusting component on the mounting part can be directly adjusted, so that the electrospray needle is driven to move, and the position adjustment of the electrospray needle in the ionization cavity is realized. Convenient and fast, improved operating personnel's work efficiency.

Description

Ionization source structure and detection equipment

Technical Field

The utility model relates to an analytical instrument technical field especially relates to ionization source structure and check out test set.

Background

electrospray-Ionization (EESI) Mass Spectrometry (MS) is a modern Ionization Mass Spectrometry technique. Research shows that factors such as ionization voltage, gas or liquid flow velocity, external environment, spatial position and angle relation between an EESI source and a sample inlet of a mass spectrometer and the like in an experiment have obvious influence on mass spectrometry signals.

During the detection and analysis of the mass spectrometer, the EESI source needs to be isolated from the external environment. In order to obtain a stronger signal, more light droplet ions with good physicochemical drying effect need to enter the cone mouth. Adjusting the relative position of the electrospray needle and the cone mouth of the ion source in space is one of the methods for achieving the purpose. Meanwhile, the existing technology cannot conveniently and quickly install and adjust the electrospray needle in place, so that an operator still has difficulty in operation.

SUMMERY OF THE UTILITY MODEL

In view of the above, it is necessary to provide an ionization source structure and a detection apparatus having a safe, reliable and stable structure.

An ionization source structure comprises an installation part and an adjusting component, wherein the installation part is used for installing detection equipment, an ionization cavity is formed in the installation part, a sample feeding channel communicated with the ionization cavity is formed in the installation part in a penetrating mode, a penetrating hole is formed in the installation part and communicated with the sample feeding channel, and the central axis of the penetrating hole is intersected with the central axis of the sample feeding channel; the adjusting component is movably arranged on the mounting component, an adjusting hole is formed in the adjusting component and communicated with the penetrating hole, and the adjusting hole is used for penetrating an electric spraying needle and enabling one end of the electric spraying needle to penetrate through the penetrating hole to be located in the ionization cavity.

In one embodiment, the ionization source structure further comprises a fixing component disposed at the adjustment hole, the fixing component configured to abut against the electrospray needle to limit movement of the electrospray needle within the adjustment hole.

In one embodiment, the fixing assembly is provided with a fixing hole, the fixing hole is communicated with the adjusting hole, the fixing hole is used for penetrating the electrospray needle, and the inner wall of the fixing hole is used for abutting against the outer surface of the electrospray needle.

In one embodiment, the fixing assembly comprises a fixing part and a rotating part, the fixing part is arranged at the position of the adjusting hole, a connecting hole is formed in the fixing part, the rotating part can be rotatably arranged in the connecting hole in a penetrating mode, the fixing hole is formed in the rotating part, and the rotating part can drive the electric spraying needle to move in the adjusting hole in a rotating mode.

In one embodiment, the adjusting assembly comprises a connecting piece and a first adjusting piece, the connecting piece is movably arranged on the mounting piece, the adjusting hole is formed in the connecting piece, the first adjusting piece is rotatably arranged on the mounting piece and connected with the connecting piece, and the first adjusting piece rotates to drive the connecting piece to move along the rotating axis direction of the first adjusting piece.

In one embodiment, the adjusting assembly further comprises a first elastic member, the first elastic member is disposed on the mounting member and abuts against a side of the connecting member facing away from the first adjusting member, and the first elastic member is capable of applying a pushing force to the connecting member in a direction toward the first adjusting member.

In one embodiment, the adjusting assembly further comprises a second adjusting member, the second adjusting member is rotatably disposed on the mounting member and connected to the connecting member, a rotation axis of the second adjusting member intersects with a rotation axis of the first adjusting member, and the second adjusting member rotates to drive the connecting member to move along the rotation axis of the second adjusting member.

In one embodiment, the adjusting assembly further comprises a second elastic member, the second elastic member is disposed on the mounting member and abuts against a side of the connecting member facing away from the second adjusting member, and the second elastic member is capable of applying a pushing force to the connecting member in a direction toward the second adjusting member.

In one embodiment, the mounting member is provided with a viewing port, the viewing port is communicated with the ionization chamber, and the viewing port upper cover is provided with a transparent member, so that the viewing port can be sealed and used for a worker to view the ionization chamber.

A detection apparatus comprising an ionization source structure as described above and a body on which the ionization source structure is mounted.

Above-mentioned ionization source structure and check out test set, when using the ionization source structure among the check out test set, the electrospray needle is worn to establish in the adjusting hole, and an end portion of electrospray needle can pass and wear to establish the hole and be located the ionization chamber, guarantees that the electrospray needle can be in the stable operation of ionization intracavity. When the sample enters the ionization chamber from the sample introduction channel, the sample can react under the action of the electrospray needle. When the position of the electrospray needle needs to be adjusted, the position of the adjusting component on the mounting part can be directly adjusted, so that the electrospray needle is driven to move, and the position adjustment of the electrospray needle in the ionization cavity is realized. Convenient and fast, has improved operating personnel's work efficiency.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification.

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained without creative efforts.

FIG. 1 is a schematic structural diagram of an ionization source configuration in one embodiment;

FIG. 2 is a front view of the ionization source structure of the embodiment of FIG. 1;

FIG. 3 is a cross-sectional view of the ionization source structure of the embodiment of FIG. 1;

fig. 4 is a cross-sectional view of another angle of the ionization source structure in the embodiment of fig. 1.

The elements in the figure are labeled as follows:

10. an ionization source structure; 100. a mounting member; 110. a sample introduction channel; 120. an ionization chamber; 130. a mounting cavity; 140. an observation port; 200. an adjustment assembly; 210. a connecting member; 211. an adjustment hole; 220. a first adjustment member; 230. a second adjustment member; 240. a first elastic member; 250. a second elastic member; 300. a fixing assembly; 310. a rotating member; 320. a fixing member; 330. a fixing hole; 400. an electrospray needle.

Detailed Description

In order to make the above objects, features and advantages of the present invention more comprehensible, embodiments of the present invention are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, as those skilled in the art will be able to make similar modifications without departing from the spirit and scope of the present invention.

Referring to fig. 1 and 2, the detection apparatus in one embodiment includes an ionization source structure 10 and a main body, and the ionization source structure 10 is mounted on the main body. The ionization source structure 10 comprises a mounting member 100 and an adjusting assembly 200, wherein the mounting member 100 is used for mounting detection equipment, an ionization chamber 120 is formed in the mounting member 100, a sample introduction channel 110 communicated with the ionization chamber 120 is formed in the mounting member 100 in a penetrating manner, a through hole is further formed in the mounting member 100, the through hole is communicated with the sample introduction channel 110, and the central axis of the through hole is intersected with the central axis of the sample introduction channel 110; the adjusting component 200 is movably disposed on the mounting member 100, an adjusting hole 211 is formed in the adjusting component 200, the adjusting hole 211 is communicated with the through hole, the adjusting hole 211 is used for allowing the electrospray needle 400 to penetrate therethrough, and one end of the electrospray needle 400 is located in the ionization chamber 120 through the through hole.

When the ionization source structure 10 in the detection device is used, the electrospray needle 400 is inserted into the adjusting hole 211, and one end of the electrospray needle 400 can penetrate through the inserting hole and be located in the ionization chamber 120, so that the electrospray needle 400 can stably run in the ionization chamber 120. After the sample enters the ionization chamber 120 from the sample inlet channel 110, the reaction can be performed by the electrospray needle 400. When the position of the electrospray needle 400 needs to be adjusted, the position of the electrospray needle 400 in the ionization chamber 120 can be adjusted by directly adjusting the position of the adjusting assembly 200 on the mounting member 100 to drive the electrospray needle 400 to move. Convenient and fast, improved operating personnel's work efficiency.

In one embodiment, the ionization source structure 10 further comprises a fixing member 300, the fixing member 300 is disposed at the adjusting hole 211, and the fixing member 300 is configured to abut against the electrospray needle 400 to limit the movement of the electrospray needle 400 within the adjusting hole 211. When the electrospray needle 400 is set to a proper position by the adjustment assembly 200, the position of the electrospray needle 400 in the adjustment hole 211 can be fixed by the fixing assembly 300, so as to ensure the stable structure of the electrospray needle 400 during the operation.

In one embodiment, the fixing assembly 300 is provided with a fixing hole 330, the fixing hole 330 is communicated with the adjusting hole 211, the fixing hole 330 is used for penetrating the electrospray needle 400, and the inner wall of the fixing hole 330 is used for abutting against the outer surface of the electrospray needle 400. The electrospray needle 400 is inserted into the adjustment hole 211 through the fixing hole 330. The fixing hole 330 increases a contact area between the fixing member 300 and the electrospray needle 400, further ensuring structural stability of the electrospray needle 400 on the fixing member 300.

In one embodiment, the fixing assembly 300 includes a fixing member 320 and a rotating member 310, the fixing member 320 is disposed at the adjusting hole 211, a connecting hole is formed on the fixing member 320, the rotating member 310 is rotatably disposed in the connecting hole, the fixing hole 330 is formed on the rotating member 310, and the rotating member 310 can drive the electrospray needle 400 to move in the adjusting hole 211 by rotating. Further, the rotating member 310 is formed with a first thread, and the fixed member 320 is formed with a second thread, the first thread and the second thread being engaged. The rotation of the rotor 310 enables the fine adjustment of the electrospray needle 400, and thus also enables the position adjustment of the electrospray needle 400.

In one embodiment, the adjusting assembly 200 includes a connecting member 210 and a first adjusting member 220, the connecting member 210 is movably disposed on the mounting member 100, the adjusting hole 211 is opened on the connecting member 210, the first adjusting member 220 is rotatably disposed on the mounting member 100 and connected to the connecting member 210, and the first adjusting member 220 rotates to drive the connecting member 210 to move along a rotation axis of the first adjusting member 220. The adjustment of the electrospray needle 400 is accomplished by rotating the first adjustment member 220 to push the connector 210 to move.

In one embodiment, the mounting member 100 has a third thread formed thereon and the first adjustment member 220 has a fourth thread formed thereon, the third thread and the fourth thread engaging. Fine adjustment of the connection member 210 is achieved by the first adjustment member 220. So that the connecting member 210 drives the electrospray needle 400 to achieve position adjustment in the ionization chamber 120.

In one embodiment, the moving direction of the rotating member 310 intersects with the rotating axis direction of the first adjusting member 220. The range of motion and the dimensions of the link 210 are broadened.

In one embodiment, the adjusting assembly 200 further comprises a first elastic member 240, the first elastic member 240 is disposed on the mounting member 100 and abuts against a side of the connecting member 210 facing away from the first adjusting member 220, and the first elastic member 240 is capable of applying a pushing force to the connecting member 210 in a direction towards the first adjusting member 220. When the first adjusting member 220 is rotated to move the link member 210 toward the first elastic member 240, the first elastic member 240 is compressed. When the first adjusting member 220 rotates away from the connecting member 210, the first elastic member 240 can push the connecting member 210 toward the first adjusting member 220, thereby achieving the movement or the restoration of the connecting member 210.

In one embodiment, the adjusting assembly 200 further includes a second adjusting member 230, the second adjusting member 230 is rotatably disposed on the mounting member 100 and connected to the connecting member 210, a rotation axis of the second adjusting member 230 intersects with a rotation axis of the first adjusting member 220, and the second adjusting member 230 rotates to drive the connecting member 210 to move along the rotation axis of the second adjusting member 230. The second adjusting member 230 is rotated to push the connecting member 210 to move, so that the electrospray needle 400 is adjusted. And the rotation axis of the second adjusting member 230 is intersected with the rotation axis of the first adjusting member 220, so that the adjusting dimension of the connecting member 210 is improved, and the application range and the use convenience of the ionization source structure 10 are enlarged.

In one embodiment, the mounting member 100 has a fifth thread formed thereon and the second adjustment member 230 has a sixth thread formed thereon, the fifth thread and the sixth thread being engaged. Fine adjustment of the connection member 210 is achieved by the second adjustment member 230. So that the connecting member 210 drives the electrospray needle 400 to achieve position adjustment in the ionization chamber 120. In cooperation with the fine adjustment of the first adjustment member 220. Further improving the reliability and utility of the ionization source structure 10.

In one embodiment, the adjusting assembly 200 further includes a second elastic member 250, the second elastic member 250 is disposed on the mounting member 100 and abuts against a side of the connecting member 210 facing away from the second adjusting member 230, and the second elastic member 250 can apply a pushing force to the connecting member 210 in a direction toward the second adjusting member 230. When the second adjusting member 230 rotates to move the link member 210 toward the second elastic member 250, the second elastic member 250 is compressed. When the second adjustment member 230 rotates away from the connection member 210, the second elastic member 250 can push the connection member 210 toward the second adjustment member 230, thereby achieving the movement or restoration of the connection member 210. The first elastic member 240 is matched to further improve the convenience of the ionization source structure 10.

In one embodiment, the mounting member 100 has a mounting cavity 130 formed therein, the connecting member 210 is movably disposed in the mounting cavity 130, one end of the first elastic member 240 abuts against an inner wall of the mounting cavity 130, and the other end of the first elastic member 240 abuts against a side of the connecting member 210 facing away from the first adjusting member 220. One end of the second elastic member 250 abuts against the inner wall of the other side of the installation cavity 130, and the other end of the second elastic member 250 abuts against the side of the connecting member 210 facing away from the second adjusting member 230.

In one embodiment, the moving direction of the rotating member 310 can intersect the rotation axis of the second adjusting member 230 and the rotation axis of the first adjusting member 220.

In one embodiment, the mounting member 100 is provided with a viewing port 140, the viewing port 140 is communicated with the ionization chamber 120, and a transparent member is covered on the viewing port 140, so that the viewing port 140 can be sealed and used for a worker to view the ionization chamber 120. The enclosed ionization chamber 120 is provided with a viewing port 140 for easy viewing by the operator, and further, for easy adjustment of the electrospray needle 400 by the operator.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and for simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

In the present application, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may directly contradict the first and second features, or indirectly contradict the first and second features through intervening media. Also, a first feature "on," "above," and "over" a second feature may be directly on or obliquely above the second feature, or simply mean that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.

All possible combinations of the technical features of the above embodiments may not be described for the sake of brevity, but should be considered as within the scope of the present disclosure as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only represent several embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the invention. It should be noted that, for those skilled in the art, without departing from the concept of the present invention, several variations and modifications can be made, which all fall within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims

1. An ionization source structure, comprising:

the device comprises an installation part, a detection device and a control part, wherein the installation part is used for installing the detection device, an ionization cavity is formed in the installation part, a sample introduction channel communicated with the ionization cavity is arranged on the installation part in a penetrating manner, a penetrating hole is also arranged on the installation part and is communicated with the sample introduction channel, and the central axis of the penetrating hole is intersected with the central axis of the sample introduction channel; and

the adjusting component is movably arranged on the mounting component, an adjusting hole is formed in the adjusting component and communicated with the penetrating hole, and the adjusting hole is used for penetrating an electric spray needle and enabling one end of the electric spray needle to penetrate through the penetrating hole to be located in the ionization cavity.

2. The ionization source structure of claim 1, further comprising a securing assembly disposed at the adjustment aperture, the securing assembly configured to abut the electrospray needle to limit movement of the electrospray needle within the adjustment aperture.

3. The ionization source structure according to claim 2, wherein the fixing member has a fixing hole, the fixing hole is communicated with the adjusting hole, the fixing hole is used for penetrating the electrospray needle, and an inner wall of the fixing hole is used for abutting against an outer surface of the electrospray needle.

4. The ionization source structure according to claim 3, wherein the fixing member includes a fixing member and a rotating member, the fixing member is disposed at the adjusting hole, the fixing member has a connecting hole, the rotating member is rotatably disposed in the connecting hole, the rotating member has the fixing hole, and the rotating member rotates to drive the electrospray needle to move in the adjusting hole.

5. The ionization source structure according to claim 1, wherein the adjusting assembly includes a connecting member and a first adjusting member, the connecting member is movably disposed on the mounting member, the connecting member has the adjusting hole, the first adjusting member is rotatably disposed on the mounting member and connected to the connecting member, and the first adjusting member rotates to drive the connecting member to move along a rotation axis of the first adjusting member.

6. The ionization source structure according to claim 5, wherein the adjustment assembly further comprises a first elastic member disposed on the mounting member and abutting against a side of the connecting member facing away from the first adjustment member, the first elastic member being capable of applying a pushing force to the connecting member in a direction toward the first adjustment member.

7. The ionization source structure of claim 5, wherein the adjustment assembly further comprises a second adjustment member rotatably disposed on the mounting member and connected to the connecting member, wherein a rotation axis of the second adjustment member intersects with a rotation axis of the first adjustment member, and the second adjustment member rotates to move the connecting member along the rotation axis of the second adjustment member.

8. The ionization source structure according to claim 7, wherein the adjustment assembly further comprises a second elastic member disposed on the mounting member and abutting against a side of the connecting member facing away from the second adjustment member, the second elastic member being capable of applying a pushing force to the connecting member in a direction toward the second adjustment member.

9. The ionization source structure according to any one of claims 1 to 8, wherein the mounting member is provided with a viewing port, the viewing port is communicated with the ionization chamber, and a transparent member is provided on the viewing port upper cover, and the transparent member can seal the viewing port and is used for a worker to view the ionization chamber.

10. A detection device, characterized in that the detection device comprises:

the ionization source structure of any one of claims 1-9; and

a body on which the ionization source structure is mounted.