CN218811694U - Conversion equipment is used in production of gamma-aminobutyric acid - Google Patents
Conversion equipment is used in production of gamma-aminobutyric acid Download PDFInfo
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- CN218811694U CN218811694U CN202320141852.7U CN202320141852U CN218811694U CN 218811694 U CN218811694 U CN 218811694U CN 202320141852 U CN202320141852 U CN 202320141852U CN 218811694 U CN218811694 U CN 218811694U
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Abstract
The utility model discloses a conversion device for producing gamma-aminobutyric acid, which comprises a base, wherein a tank body is fixed on the base, a stirring device is arranged in the tank body, an air inlet pipe is arranged at the side edge of the tank body, the air inlet pipe is close to the bottom of the tank body, one end of the air inlet pipe is connected with an air pump, and the other end of the air inlet pipe is positioned in the tank body; a first pipeline is arranged on the side wall of the tank body and is positioned above the air inlet pipe; one end of the first pipeline is positioned in the tank body, the other end of the first pipeline is connected with a second pipeline and a third pipeline, and the second pipeline and the third pipeline are arranged in parallel; the first pipeline is provided with a circulating pump, the second pipeline is connected with a material supplementing barrel, and the third pipeline is connected with the tank body and extends into the tank body; a first valve is arranged on the first pipeline, a second valve is arranged on the second pipeline, and a third valve is arranged on the third pipeline. The utility model discloses can realize the abundant mixing of conversion thalli and substrate, promote enzymatic reaction to go on, improve enzyme conversion efficiency.
Description
Technical Field
The utility model relates to a gamma-aminobutyric acid production facility technical field specifically is a conversion equipment is used in gamma-aminobutyric acid production.
Background
Gamma-aminobutyric acid is an important inhibitory neurotransmitter, has various physiological functions, and is widely applied to food, medicines and feed additives. The main production method at present is a biotransformation method, and the process of the method is to construct escherichia coli which can express glutamate decarboxylase efficiently by gene technology, and to perform high-density fermentation, and to perform biotransformation after obtaining thalli.
The biological conversion process of gamma-aminobutyric acid is to set thallus, substrate, converting liquid and stirrer inside a converting tank to disperse thallus homogeneously in the converting liquid and to promote the conversion.
In the existing conversion tank, the bottom end of a stirring shaft is a certain distance away from the bottom of the conversion tank, and the thallus has a weight, so that a vortex-shaped area can be formed at the lower part of a stirring paddle, and the thallus in the area is difficult to better participate in the conversion process, and in the conversion process of gamma-aminobutyric acid, the dispersion degree of the thallus in a conversion solution and the dissolution degree of a substrate glutamic acid or sodium glutamate in the conversion solution have important influence on the production conversion efficiency of the gamma-aminobutyric acid, so that the conversion device capable of uniformly dispersing the thallus and the substrate and improving the conversion efficiency has important significance.
Disclosure of Invention
In order to solve the technical problem, the utility model aims at providing a conversion equipment is used in gamma-aminobutyric acid production, and this conversion equipment can make the thallus fully dispersed in the conversion liquid and can make the substrate distribute evenly, and then improves gamma-aminobutyric acid conversion efficiency.
In order to achieve the technical purpose, the technical scheme of the utility model is as follows:
a conversion device for producing gamma-aminobutyric acid comprises a base, wherein a tank body is fixed on the base, and a stirring device is arranged in the tank body;
an air inlet pipe is arranged on the side edge of the tank body, the air inlet pipe is close to the bottom of the tank body, one end of the air inlet pipe is connected with an air pump, and the other end of the air inlet pipe is positioned in the tank body;
the air pump injects gas into the tank body through the air inlet pipe to disturb an area below the stirring device, so that the thalli are prevented from depositing in the area, and under the synergistic action of the air pump and the stirring device, the thalli are enabled to participate in the conversion of gamma-aminobutyric acid as much as possible, and the conversion rate is improved;
in order to further improve the conversion efficiency, a first pipeline is arranged on the side wall of the tank body and is positioned above the air inlet pipe;
one end of the first pipeline is positioned in the tank body, the other end of the first pipeline is connected with a second pipeline and a third pipeline, and the second pipeline and the third pipeline are arranged in parallel;
the first pipeline is provided with a circulating pump, the second pipeline is connected with a material supplementing barrel, and the third pipeline is connected with the tank body and extends into the tank body;
a first valve is arranged on the first pipeline, a second valve is arranged on the second pipeline, and a third valve is arranged on the third pipeline.
Preferably, the top surface of the tank body is also provided with a feed inlet, the side wall of the tank body is provided with a discharge outlet, and the discharge outlet is close to the bottom of the tank body.
Preferably, the stirring device comprises a motor, and the motor is arranged on the top surface of the tank body; the motor is connected with the (mixing) shaft, and the bottom of (mixing) shaft stretches into the inside of jar body, installs the stirring rake on the (mixing) shaft.
Preferably, the extension line of the end part of the air inlet pipe positioned in the tank body is positioned below the stirring device.
Preferably, in order to monitor the conversion solution condition in the tank body, the side wall of the tank body is provided with a temperature electrode and a pH electrode, so that the change of the conversion solution can be better monitored.
Preferably, a spray header is arranged in the tank body, and the third pipeline is connected with the spray header; can spray liquid more uniformly, so that thalli and substrates can be distributed in the conversion solution more uniformly, and the conversion rate is further improved.
Preferably, the first valve is located after the circulation pump and before the second and third pipes.
1. Through setting up air pump and intake pipe, can produce the stirring area of agitating unit below and disturb, avoid the thallus to deposit in agitating unit's below, make the thallus participate in the process of changeing and then improve the conversion rate.
2. Through setting up first pipeline, second pipeline, third pipeline, circulating pump and feed supplement bucket, can enough make the thallus that drops into in the buffer solution distribute evenly, can realize dropping into the bed charge in turn again in the conversion process, further improve conversion efficiency.
3. The conversion device provided by the invention has the advantages of reasonable design and strong practicability; the conversion device can improve the biological conversion efficiency of the gamma-amino acid.
Drawings
Fig. 1 is a schematic structural diagram of a conversion device for producing gamma-aminobutyric acid according to the present invention.
Description of the main structure: 1. a tank body; 2. a feed inlet; 3. a stirring shaft; 4. a shower head; 5. a stirring paddle; 6. a temperature electrode; 7. a pH electrode; 8. a discharge outlet; 9. a base; 10. a motor; 11. a third valve; 12. a material supplementing barrel; 13. a second valve; 14. a first valve; 15. a circulation pump; 16. a first conduit; 17. a second conduit; 18. a third pipeline; 19. an air inlet pipe; 20. an air pump.
Detailed Description
In order to better understand the present invention for those skilled in the art, the technical solutions of the present invention are further explained below with reference to the drawings and the embodiments.
Example 1: the utility model relates to a conversion device for producing gamma-aminobutyric acid, which comprises a base 9, wherein a tank body 1 is arranged on the base 9, a feed inlet 2 is arranged at the top of the tank body 1, a discharge outlet 8 is arranged on the side surface of the tank body, and the discharge outlet 8 is close to the bottom of the tank body 1;
in order to facilitate the monitoring of the conversion solution in the tank body 1, a temperature electrode 6 and a pH electrode 7 are arranged on the side surface of the tank body 1, wherein in the embodiment, the temperature electrode 6 is positioned above the pH electrode 7;
a motor 10 is arranged at the top of the tank body 1, the motor 10 is connected with a stirring shaft 3, and a stirring paddle 5 is arranged on the stirring shaft 3;
an air inlet pipe 19 is arranged on the side wall of the tank body 1, the air inlet pipe 19 is close to the bottom of the tank body 1, one end of the air inlet pipe 19 is connected with an air pump 20, and the other end of the air inlet pipe is positioned in the tank body 1;
when the air pump 20 is started to ventilate into the tank body 1, gas sprayed out of the air inlet pipe 19 disturbs a liquid area below the stirring shaft 3, the movement law of thalli is changed, the air inlet pipe is matched with the stirring paddle 5 to act on the thalli, stirring dead angles are avoided, the thalli are promoted to participate in a conversion process as much as possible, and the conversion efficiency is improved;
in order to further improve the conversion efficiency, a first pipeline 16 is also arranged on the side wall of the tank body 1, and the first pipeline 16 is positioned above the air inlet pipe 19;
one end of the first pipeline 16 is positioned in the tank body 1, the other end of the first pipeline is connected with a second pipeline 17 and a third pipeline 18, and the second pipeline 17 and the third pipeline 18 are arranged in parallel;
a circulating pump 15 is arranged on the first pipeline 16, a material supplementing barrel 12 is connected on the second pipeline 17, and a third pipeline 18 is connected with the tank body 1, extends into the tank body 1 and is connected with a spray header 4 in the tank body 1;
a first valve 14 is installed on the first pipe 16, and the first valve 14 is positioned after the circulating pump 15 and before the second pipe 17 and the third pipe 18;
a second valve 13 is mounted on the second conduit 17 and a third valve 11 is mounted on the third conduit 18.
The specific working process is as follows:
the method comprises the following steps: before the conversion begins, the thalli and buffer solution are put into the tank body 1 through the feed inlet 2 of the conversion device, and the motor 10 is started;
opening the first valve 14 and the third valve 11, closing the second valve 13, pumping the mixed solution containing the buffer solution and the thalli in the tank body 1 into the spray head 4 by the circulating pump 15 for spraying, so that the thalli are uniformly distributed in the tank body 1 as far as possible;
step two: continuing stirring, opening a first valve 14 and a second valve 13, closing a third valve 11, pumping the mixed solution into a material supplementing barrel 12 by using a circulating pump 15, adding a conversion substrate of glutamic acid (sodium) into the material supplementing barrel 12 for full dissolution, then closing the first valve 14, opening the second valve 13 and the third valve 11, enabling the dissolved substrate to uniformly flow into the tank body 1 through a spray header 4, and starting conversion;
step three: in the conversion process, the air pump 20 is periodically started, and air is intermittently introduced into the tank body 1 through the air inlet pipe 19, wherein the air is introduced every 15 minutes in the embodiment;
step four: and (4) after the substrate in the conversion solution in the tank body 1 is completely consumed, continuously repeating the step two, adding the substrate, and repeating for multiple times until the conversion is finished.
Claims (7)
1. A conversion device for producing gamma-aminobutyric acid comprises a base, a tank body is fixed on the base, a stirring device is arranged in the tank body, and the conversion device is characterized in that,
an air inlet pipe is arranged on the side edge of the tank body, the air inlet pipe is close to the bottom of the tank body, one end of the air inlet pipe is connected with an air pump, and the other end of the air inlet pipe is positioned in the tank body;
a first pipeline is arranged on the side wall of the tank body and positioned above the air inlet pipe;
one end of the first pipeline is positioned in the tank body, the other end of the first pipeline is connected with a second pipeline and a third pipeline, and the second pipeline and the third pipeline are arranged in parallel;
the first pipeline is provided with a circulating pump, the second pipeline is connected with a material supplementing barrel, and the third pipeline is connected with the tank body and extends into the tank body;
a first valve is arranged on the first pipeline, a second valve is arranged on the second pipeline, and a third valve is arranged on the third pipeline.
2. The conversion apparatus for producing gamma-aminobutyric acid according to claim 1,
the top surface of the tank body is also provided with a feed inlet, the side wall of the tank body is provided with a discharge outlet, and the discharge outlet is close to the bottom of the tank body.
3. The apparatus for converting γ -aminobutyric acid production according to claim 1, wherein said stirring means comprises a motor installed on a top surface of said tank; the motor is connected with the (mixing) shaft, and the bottom of (mixing) shaft stretches into the inside of jar body, installs the stirring rake on the (mixing) shaft.
4. The apparatus for converting γ -aminobutyric acid according to claim 3, wherein an extension line of an end of the gas inlet pipe located inside the tank body is located below the stirring shaft.
5. The apparatus for converting γ -aminobutyric acid according to claim 1, wherein a temperature electrode and a pH electrode are provided on a sidewall of the tank.
6. The conversion apparatus for producing gamma-aminobutyric acid according to claim 1, wherein a shower head is provided in the tank, and the third pipe is connected to the shower head.
7. The apparatus of claim 1, wherein the first valve is located after the circulation pump and before the second and third pipes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320141852.7U CN218811694U (en) | 2023-02-07 | 2023-02-07 | Conversion equipment is used in production of gamma-aminobutyric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320141852.7U CN218811694U (en) | 2023-02-07 | 2023-02-07 | Conversion equipment is used in production of gamma-aminobutyric acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218811694U true CN218811694U (en) | 2023-04-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320141852.7U Active CN218811694U (en) | 2023-02-07 | 2023-02-07 | Conversion equipment is used in production of gamma-aminobutyric acid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218811694U (en) |
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2023
- 2023-02-07 CN CN202320141852.7U patent/CN218811694U/en active Active
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